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VSRITTDQLRDAVLDEGSFISWDTPPLEVPISESYARDLADARAATGRDESVLTGEGRVLGRRVAVVVCE FDFLAGSIGVAAAERITAAVERATRQRLPLLASPSSGGTRMQEGTVAFLQMVKIAAAVRLHKQAHLPYLV YLRHPTTGGVFASWGSLGHVTVAEPGALIGFLGPRVYELLYDEPFPAGIQTAENLQRHGVIDGVVTLDEL RRTLDRALTVLTDAPAPAPAAPAPTAIPDVPAWTSVLASRRPDRPGVEHLLRYGATDRVLLSGTGYGDAA TTLLALARMAGQPMVVLGQQGIGGGIIGPASLREARRGMALAAELRLPLVLVIDTAGPALSADAEQGGLA GQIAQCLAELVTLGTPTVSVLLGQGSGGPALAMVPADRVLAAQHGWLAPLPPEGASAIVFRDTTHAAELA AAQGIRSADLLAAGIVDVIVPELPDAAAEPVEFAQRLSIAIATEVAALREIPDAQRMTARLARYRSIGLP RDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4626 | accD3 | - | 100% (493) | acetyl-coenzyme A carboxylase carboxyl transferase (subunit beta) AccD3 |
| M. marinum M | MMAR_1256 | accD5 | 7e-14 | 23.42% (427) | propionyl-CoA carboxylase beta chain 5 AccD5 |
| M. marinum M | MMAR_3340 | accD6 | 2e-13 | 23.92% (439) | acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0928c | accD3 | 0.0 | 81.82% (495) | putative acetyl-coenzyme A carboxylase carboxyl transferase |
| M. gilvum PYR-GCK | Mflv_1754 | - | 0.0 | 76.07% (489) | carboxyl transferase |
| M. tuberculosis H37Rv | Rv0904c | accD3 | 0.0 | 81.82% (495) | putative acetyl-coenzyme A carboxylase carboxyl transferase |
| M. leprae Br4923 | MLBr_01657 | - | 7e-12 | 22.12% (434) | acetyl/propionyl CoA carboxylase beta subunit |
| M. abscessus ATCC 19977 | MAB_4676 | - | 3e-16 | 26.06% (495) | putative carboxyl transferase/pyruvate carboxylase |
| M. avium 104 | MAV_2190 | - | 4e-15 | 23.95% (430) | propionyl-CoA carboxylase beta chain |
| M. smegmatis MC2 155 | MSMEG_5642 | - | 0.0 | 77.91% (489) | acetyl-coenzyme a carboxylase carboxyl transferase |
| M. thermoresistible (build 8) | TH_0091 | accD3 | 0.0 | 74.80% (492) | PUTATIVE ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE |
| M. ulcerans Agy99 | MUL_0237 | accD3 | 0.0 | 98.38% (493) | acetyl-coenzyme a carboxylase carboxyl transferase (subunit |
| M. vanbaalenii PYR-1 | Mvan_4993 | - | 0.0 | 79.59% (490) | carboxyl transferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4626|M.marinum_M ----------------------------------MSRITTDQLRDAVLDE
MUL_0237|M.ulcerans_Agy99 ----------------------------------MSRITTDQLRDAVLDE
Mb0928c|M.bovis_AF2122/97 ----------------------------------MSRITTDQLRHAVLDR
Rv0904c|M.tuberculosis_H37Rv ----------------------------------MSRITTDQLRHAVLDR
Mflv_1754|M.gilvum_PYR-GCK ----------------------------------MSRIGALALRDAVLDE
Mvan_4993|M.vanbaalenii_PYR-1 ----------------------------------MSRIRALALRDALLDE
MSMEG_5642|M.smegmatis_MC2_155 ----------------------------------MSRIGALALRDAVLDE
TH_0091|M.thermoresistible__bu ----------------------------------MSRIGAVQFVETVLDT
MLBr_01657|M.leprae_Br4923 ----------------------------------MTITAPKVVGKSIDPR
MAV_2190|M.avium_104 ----------------------------------MTITAPETVGESLDPR
MAB_4676|M.abscessus_ATCC_1997 MADEQLREDHVELLARRALTEDAARPDAVARRHAAGGRTARENISDLVDA
. :
MMAR_4626|M.marinum_M GSFISWDTPPLEVPISESYARDLADARAATGRDESVLTGEGRVLGRR---
MUL_0237|M.ulcerans_Agy99 DSFISWDTPPLEVPISESYARDLADVRAATGRDESVLTGEGRVLGRR---
Mb0928c|M.bovis_AF2122/97 GSFVSWDSEPLAVPVADSYARELAAARAATGADESVQTGEGRVFGRR---
Rv0904c|M.tuberculosis_H37Rv GSFVSWDSEPLAVPVADSYARELAAARAATGADESVQTGEGRVFGRR---
Mflv_1754|M.gilvum_PYR-GCK GSFLSWDRPPIPVVTSAEYRAELAAAADATGLDESVVTGEGRVFGRR---
Mvan_4993|M.vanbaalenii_PYR-1 GSFVSWDGPPLAVPTSAEYRRELAEAEAATGLDESVLTGEGRVFGRR---
MSMEG_5642|M.smegmatis_MC2_155 GSFRSWDTAPLDVGADDEYRRELAEASAKTGLDESVLTGEGTVFGRR---
TH_0091|M.thermoresistible__bu GSFVSWDDPPLAIPADEDYRRELTDAAAVTGLDEAVLTGEGTIFGRR---
MLBr_01657|M.leprae_Br4923 DPLLRLSN------FFDDGRVEPLHERNQSG----VFAATGTVNGLR---
MAV_2190|M.avium_104 DPLLRLSN------FFDDGSVALLHERDRSG----VLAAAGTVNGVR---
MAB_4676|M.abscessus_ATCC_1997 GSFVEYGRFAIAAQRRRRELADLIARTPADGLVAGTARVNGNLFGADRSA
..: . * . * : *
MMAR_4626|M.marinum_M VAVVVCEFDFLAGSIGVAAAERITAAVERATRQRLPLLASPSSGGTRMQE
MUL_0237|M.ulcerans_Agy99 VAVVACEFDFLAGSIGVAAAERITAAMERATSQRLPLLASPSSGGTRMQE
Mb0928c|M.bovis_AF2122/97 VAVVACEFDFLGGSIGVAAAERITAAVERATAERLPLLASPSSGGTRMQE
Rv0904c|M.tuberculosis_H37Rv VAVVACEFDFLGGSIGVAAAERITAAVERATAERLPLLASPSSGGTRMQE
Mflv_1754|M.gilvum_PYR-GCK VALIACEFDFLAGSIGVAAAERITAAVQRATAEGLPLLASPSSGGTRMQE
Mvan_4993|M.vanbaalenii_PYR-1 VALIACEFDFLAGSIGVAAAERIIAAVQKATAERLPLLASPSSGGTRMQE
MSMEG_5642|M.smegmatis_MC2_155 VAVVACEFDFLAGSIGVAAAERITAAVQRATAERLPLLASPSSGGTRMQE
TH_0091|M.thermoresistible__bu VALVACEFDFLAGSIGVAAAERIVAAVQRATAERLPLVASPSSGGTRMQE
MLBr_01657|M.leprae_Br4923 TIAFCTDGTVMGGAMGIEGCAHIVNAYDTAIEEQSPIVGIWHSGGARLAE
MAV_2190|M.avium_104 TIAFCTDGTVMGGAMGIEGCSHIVDAYDTAIEEQSPIVGIWHSGGARLAE
MAB_4676|M.abscessus_ATCC_1997 CAVLSYDYTVLAGTQGALGHHKKDRLFDLIERMKLPTVFFAEGGGGRPGD
. : .:.*: * . : : * : .** * :
MMAR_4626|M.marinum_M GTVAFLQMVKI-AAAVRLHKQAHLPYLVYLRHPTTGGVFASWG-SLGHVT
MUL_0237|M.ulcerans_Agy99 GTVAFLQMVKI-AAAVRLHKQAHLPYLVYLRHPTTGGVFASWG-SLGHVT
Mb0928c|M.bovis_AF2122/97 GTVAFLQMVKI-AAAIQLHNQARLPYLVYLRHPTTGGVFASWG-SLGHLT
Rv0904c|M.tuberculosis_H37Rv GTVAFLQMVKI-AAAIQLHNQARLPYLVYLRHPTTGGVFASWG-SLGHLT
Mflv_1754|M.gilvum_PYR-GCK GTVAFLQMVKI-AAAVELHKKGNLPYLVYLRHPTTGGVFASWG-SLGHVT
Mvan_4993|M.vanbaalenii_PYR-1 GTVAFLQMVKI-AAAVELHKKAHLPYLVYLRHPTTGGVFASWG-SLGHVT
MSMEG_5642|M.smegmatis_MC2_155 GTVAFLQMVKI-AAAVELHKQAHLPYLVYLRHPTTGGVFASWG-SLGHVT
TH_0091|M.thermoresistible__bu GTVAFLQMVKI-AAAVQLHKLAHLSYLVYLRHPTTGGVFASWG-SLGHIT
MLBr_01657|M.leprae_Br4923 G-VRALHAVGQ-VFEAMIRASGYIPQISVVVGFAAGG--AAYGPALTDVV
MAV_2190|M.avium_104 G-VKALHAVGL-VFEAMIRASGYIPQISVVVGFAAGG--AAYGPALTDVV
MAB_4676|M.abscessus_ATCC_1997 TDYPVVSMLDVRAFKLWAALSGVVPRISVVNGRCFAGNAVIAG--CSDLI
: : . . :. : : .* . * .:
MMAR_4626|M.marinum_M VAEPGALIGFLGPRVYELLYDEPFPAG-IQTAENLQRHGVIDGVVTLDEL
MUL_0237|M.ulcerans_Agy99 VAEPGALIGFLGPRVYELLYDEPFPAG-VQTAENLQRHGVIDGVVTLDEL
Mb0928c|M.bovis_AF2122/97 VAEPGALIGFLGPRVYELLYGDPFPSG-VQTAENLRRHGIIDGVVALDRL
Rv0904c|M.tuberculosis_H37Rv VAEPGALIGFLGPRVYELLYGDPFPSG-VQTAENLRRHGIIDGVVALDRL
Mflv_1754|M.gilvum_PYR-GCK AAEPDALIGFLGPRVYEHLYGERFPSG-VQTSENLQRHGVIDAVVPLEVL
Mvan_4993|M.vanbaalenii_PYR-1 AAEPGALIGFLGPRVYEHLYGEPFPAG-IQTAENLHRHGVVDAVIPPGIL
MSMEG_5642|M.smegmatis_MC2_155 AAEPGALIGFLGPRVYEHLYGEPFPSG-VQTAENLHAHGVIDGVVPLALL
TH_0091|M.thermoresistible__bu IAEPNALIGFLGPRVYQHLYGEPFPPG-VQTAENLHRHGVIDSVVPLPRL
MLBr_01657|M.leprae_Br4923 IMAPEGRVFVTGPDVVRSVTGEDVDMASLGGPETHHKKSGVCHIVANDEL
MAV_2190|M.avium_104 VMAPESRVFVTGPDVVRSVTGEDVDMASLGGPETHHKKSGVCHIVADDEL
MAB_4676|M.abscessus_ATCC_1997 VATKDTSIGMGGPAMIAGGGLGEVHPDEVGPIAVQSTNGVVDVVVDDEEQ
: . ** : . : :. : ::
MMAR_4626|M.marinum_M RRTLDRALTVLTDAPAPAPAAPAPT-AIPDVPAWTSVLASRRPDRPGVEH
MUL_0237|M.ulcerans_Agy99 RRTLDRALTVLTDAPAPAPAAPAPP-AIPDVAAWTSVLASRRPDRPGVEH
Mb0928c|M.bovis_AF2122/97 RPMLDRALTVLIDAPEPLPAPQTPA-PVPDVPTWDSVVASRRPDRPGVRQ
Rv0904c|M.tuberculosis_H37Rv RPMLDRALTVLIDAPEPLPAPQTPA-PVPDVPTWDSVVASRRPDRPGVRQ
Mflv_1754|M.gilvum_PYR-GCK RATVDRTLKVVADAPGPPPAAPEPE-VLPDIPAWDSVEISRRPDRPGVSF
Mvan_4993|M.vanbaalenii_PYR-1 RATLDRALRVVSDAPDVPPAAPDAE-PLPDVPAWESVEISRRPDRPGVSA
MSMEG_5642|M.smegmatis_MC2_155 RETLDRTLRVVADPPGPAPAVIETE-DLPDVPAWDSVIASRRPDRPGVGF
TH_0091|M.thermoresistible__bu RSELDRALRVLVDEPGTPPAPPDVDTSQPDVPAWDSVIASRRPDRPGVGY
MLBr_01657|M.leprae_Br4923 DAYERGRRLVGLFCQQGHFDRSKAEAGDTNIQALLPESSRRAYD---VHP
MAV_2190|M.avium_104 DAYERGRRLVGLFCQQGHFDRTKAEAGDTDIHALLPESARRAYD---VRP
MAB_4676|M.abscessus_ATCC_1997 AVTVAKRLISYFQGAVAPGDGADQT----ALRTMIPERARRAYP---IRP
: : . * :
MMAR_4626|M.marinum_M LLRYGATDRVLLSGTGYGDAATTLLALARMAGQPMVVLGQQ-GIGGG--I
MUL_0237|M.ulcerans_Agy99 LLRYGATDRVLLSGTGYGDAATTLLALARMAGQPMVVLGQQ-GIGGG--I
Mb0928c|M.bovis_AF2122/97 LLRHGATDRVLLSGTDQGEAATTLLALARFGGQPTVVLGQQRAVGGGGST
Rv0904c|M.tuberculosis_H37Rv LLRHGATDRVLLSGTDQGEAATTLLALARFGGQPTVVLGQQRAVGGGGST
Mflv_1754|M.gilvum_PYR-GCK LLRHGATERVLLSGTGQGESATMMLALARFGNQPAVVLGQQ-RVVGG--L
Mvan_4993|M.vanbaalenii_PYR-1 LLRYGTTDRVLLSGTGQGEAATTLLALARFGGQPAVVLGQQ-RVVGG--L
MSMEG_5642|M.smegmatis_MC2_155 LLRHGATDQVLLSGTERGEAATTLLALARFGGQPAVVLGQR-RIVGG--L
TH_0091|M.thermoresistible__bu LLRHGATDTVLLSGSGGGEAATTLLALARFGGQPAVVLGQQ-RVIGA--M
MLBr_01657|M.leprae_Br4923 VVTAILDENTPFDEFQANWAPSMVVGLGRLSGRTVGVLANNPLRLGG--C
MAV_2190|M.avium_104 IVTAILDDETPFDEFQANWAPSMVIGLGRLSGRTVGVLANNPLRLGG--C
MAB_4676|M.abscessus_ATCC_1997 IIET-LADTGSVTFLREKFAPEMATALARIEGRPIGVLANNSMVMAG--A
:: : . :. .*.*: .:. **.:. ..
MMAR_4626|M.marinum_M IGPASLREARRGMALAAELRLPLVLVIDTAGPALSADAEQGGLAGQIAQC
MUL_0237|M.ulcerans_Agy99 IGPASLREARRGMALAAELRLPLVLVIDTAGPALSADAEQGGLAGQIAQC
Mb0928c|M.bovis_AF2122/97 VGPAALREARRGMALAAELCLPLVLVIDAAGPALSAAAEQGGLAGQIAHC
Rv0904c|M.tuberculosis_H37Rv VGPAALREARRGMALAAELCLPLVLVIDAAGPALSAAAEQGGLAGQIAHC
Mflv_1754|M.gilvum_PYR-GCK VGPAALREARRGMALAASLKLPLVLVIDTAGPALSTEAEEGGLAGEIARC
Mvan_4993|M.vanbaalenii_PYR-1 VGPAALREARRGMALAAGLKLPLVLVIDTAGPALSTEAEEGGLAGEIARC
MSMEG_5642|M.smegmatis_MC2_155 VGPGALREARRGMALAAGLQLPLVLVIDTAGPALSTEAEQGGLAGEIARC
TH_0091|M.thermoresistible__bu VGPAALREARRGMALAADLQLPLVLVIDTAGPALTAEAEQGGLASEIAHC
MLBr_01657|M.leprae_Br4923 LNSESAEKAARFVRLCDAFGIPLVVIVDVPGYLPGVDQEWGGVVRRGAKL
MAV_2190|M.avium_104 LNSESAEKAARFVRLCDAFGIPLVVIVDVPGYLPGVDQEWGGVVRRGAKL
MAB_4676|M.abscessus_ATCC_1997 ITAAASDKAARFLQLCDAFGLPVLSLVDCPGYMVGPAAEAEALVRRASRM
: . : :* * : *. : :*:: ::* .* * .:. . ::
MMAR_4626|M.marinum_M LAELVTLGTPTVSVLLGQGSGGPALAMVPADRVLAAQ-HGWLAPLPPEGA
MUL_0237|M.ulcerans_Agy99 LAELVTLGTPTVSVLLGQGSGGPALAMVPADRVLAAQ-HGWLAPLPPEGA
Mb0928c|M.bovis_AF2122/97 LAELVTLDTPTVSILLGQGSGGPALAMLPADRVLAAL-HGWLAPLPPEGA
Rv0904c|M.tuberculosis_H37Rv LAELVTLDTPTVSILLGQGSGGPALAMLPADRVLAAL-HGWLAPLPPEGA
Mflv_1754|M.gilvum_PYR-GCK LAELVTLDTPTVSVLLGQGSGGPALAMVPADRVLAAL-HGWLAPLPPEGA
Mvan_4993|M.vanbaalenii_PYR-1 LAELVTLDTPTVSVLLGQGSGGPALAMVPADRVLAAL-HGWLAPLPPEGA
MSMEG_5642|M.smegmatis_MC2_155 LAELVTLDTPTVSVLMGQGSGGPALAMVPADRVLAAS-NGWLAPLPPEGA
TH_0091|M.thermoresistible__bu LAELVTLDTATLSVLLGQGSGGPALAMVPADRVLAAR-HGWLAPLPPEGV
MLBr_01657|M.leprae_Br4923 LHAFGECTVPRVTLVTRKTYGGAYIAMNSRSLNATKV-FAWPD------A
MAV_2190|M.avium_104 LHAFGEATVPRVTLVTRKTYGGAYIAMNSRSLNATKV-FAWPD------A
MAB_4676|M.abscessus_ATCC_1997 LVAGAALRVPLVSVILRRGYGLGAQAMTGGSLHEPLLTVAWPN----AHL
* .. :::: : * ** . . .*
MMAR_4626|M.marinum_M SAIVFRDTTHAAELAAAQGIRSADLLAAGIVDVIVPELPDAAA--EPVEF
MUL_0237|M.ulcerans_Agy99 SAIVFRDTTHAAELAAAQGIRSADLLAAGIVDVIVPELPDAAA--EPVEF
Mb0928c|M.bovis_AF2122/97 SAIVFRDTAHAAELAAAQGIRSADLLKSGIVDTIVPEYPDAAD--EPIEF
Rv0904c|M.tuberculosis_H37Rv SAIVFRDTAHAAELAAAQGIRSADLLKSGIVDTIVPEYPDAAD--EPIEF
Mflv_1754|M.gilvum_PYR-GCK SAIVFRDVDHAPELAAAQGIRSVDLLRDGIVDAVVPEHPDAAD--EPRAF
Mvan_4993|M.vanbaalenii_PYR-1 SAIVFRDVDHAPELAAAQGIRSADLLRNGIVDAIVPEHPDAAD--EPQAF
MSMEG_5642|M.smegmatis_MC2_155 SAIVYRDTEHAPELAAAQGVRAVDLLRHGIVDVVVAEKPDAAD--EPRAF
TH_0091|M.thermoresistible__bu SAIVHRDLDHAPELAARQGIRSVDLLRHGIVDAIVDERPDAAD--EPMEF
MLBr_01657|M.leprae_Br4923 EVAVMGAKAAVGILHKRKLAAAPNDEREALHDDLAAEHERIAGGVDSAID
MAV_2190|M.avium_104 EVAVMGAKAAVGILHKKKLAAAPEHEREALHDQLAAEHEKIAGGVDSAIE
MAB_4676|M.abscessus_ATCC_1997 GPMGLEGAVRLGLRKELEAIADESAREEAVRQATAAAQENAKA--INAAQ
: . .: : .
MMAR_4626|M.marinum_M AQRLSIAIATEVAALREIPDAQRMTARLARYRSIGLPRDR
MUL_0237|M.ulcerans_Agy99 AQRLSIAIATEVAALREIPDAQRMTARLARYRSIGLPRDR
Mb0928c|M.bovis_AF2122/97 ALRLSNAIAAEVHALRKIPAPERLATRLQRYRRIGLPRD-
Rv0904c|M.tuberculosis_H37Rv ALRLSNAIAAEVHALRKIPAPERLATRLQRYRRIGLPRD-
Mflv_1754|M.gilvum_PYR-GCK VERLSATIAVELHRLRFAPEAERSASRLERYRRIGLA---
Mvan_4993|M.vanbaalenii_PYR-1 TQRLSATIAVELHRLRTVPDEQRLAARLERYRRIGLP---
MSMEG_5642|M.smegmatis_MC2_155 TARLSTAIAAELHNLRAVPDDERLQTRLQRYRRIGL----
TH_0091|M.thermoresistible__bu TARLADSIAVELHRLREMPAESRLETRLARYRRIGLPR--
MLBr_01657|M.leprae_Br4923 IGVVDEKINPAHTRSKLTEALAQSPVRRGRHKNIPL----
MAV_2190|M.avium_104 IGVVDEKIDPAHTRSKLTEALAQAPARRGRHKNIPL----
MAB_4676|M.abscessus_ATCC_1997 IFEIDDVIDPAETRSLVASTFAAAMREPLPLRRSVVDTW-
: * . : :