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ILDLSDDALEYGLQALHAFENAGGDRLVEQAEADPTARHGLVRPVLDGLGAWDLDPRTDADGLEAAAALC RSAGYWALPYPLAERLAKPADLDVDGLVVVGGPRPAAALGGLDLRWAAVDLDGRRALVTGQGVTGPGFVA ELELSPVDSDGSRDVALALVLPCWTLLGILDRAVALTVAHVSLRKQFGQTLSSFQGVQFQLTDAEVERSG VDILAKHALWSIATDQSHVVDDALALRMAAIEAADVVFRVCHQLHGAVGFCDETTLSWLSRYSLPLRRLP FGLSSTRDHLTRVAGRRGLTGLFI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4957 | - | - | 100% (305) | acyl-CoA dehydrogenase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_5207 | - | 2e-11 | 30.00% (180) | acyl-CoA dehydrogenase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3918 | - | 2e-10 | 37.84% (111) | acyl-CoA dehydrogenase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3574c | fadE28 | 4e-12 | 30.04% (283) | acyl-CoA dehydrogenase FADE28 |
| M. gilvum PYR-GCK | Mflv_1793 | - | 1e-146 | 83.55% (304) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3544c | fadE28 | 4e-12 | 30.04% (283) | acyl-CoA dehydrogenase FADE28 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0594c | - | 3e-12 | 27.37% (274) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_3982 | - | 6e-42 | 37.99% (308) | acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1628 | - | 9e-41 | 39.30% (285) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5621 | - | 1e-134 | 78.69% (305) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_0680 | - | 1e-124 | 72.37% (304) | putative acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_3843 | - | 2e-39 | 36.69% (308) | acyl-CoA dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4957|M.vanbaalenii_PYR-1 -------------------MILDLSDDALEYG-LQALHAFENAGGD---R
Mflv_1793|M.gilvum_PYR-GCK -------------------MILDLSDDALEFG-RQALHAFENAGGD---R
MSMEG_5621|M.smegmatis_MC2_155 -------------------MILDLSDDAEEFG-HQALRAFESAGGD---E
TH_0680|M.thermoresistible__bu ---------------MDGPMILDLSDDALEYG-RQALRAFEAAGGD---E
MMAR_3982|M.marinum_M -------------------MNTELPQDIIEFA-RVAAKRLARVGGP---P
MUL_3843|M.ulcerans_Agy99 -------------------MNTELPQDVIDFA-RVAAKRLARVGGP---P
MAV_1628|M.avium_104 -------------------MKTDLPQDISDFA-TVAAKRFTRLGGP---P
Mb3574c|M.bovis_AF2122/97 MDFDPTAEQQAVADVVTSVLERDISWEALVCGGVTALPVPERLGGDGVGL
Rv3544c|M.tuberculosis_H37Rv MDFDPTAEQQAVADVVTSVLERDISWEALVCGGVTALPVPERLGGDGVGL
MAB_0594c|M.abscessus_ATCC_199 ---------MKFDLDTQQRDFAASIDAALSVADVPAAARAWAAGNHGPGL
. * *.
Mvan_4957|M.vanbaalenii_PYR-1 LVEQAEADPTARHGLVRPVLDGLGAWDLDPRTDADGL----EAAAALCRS
Mflv_1793|M.gilvum_PYR-GCK LAEQAEADPAARQTLVAPVLDGLGAWDLDPRTDPDGL----EAAAALCRS
MSMEG_5621|M.smegmatis_MC2_155 LLQQAEAKPDARQGLVGPVLDGLGAWDLDPRSDADAL----EAAAALCRS
TH_0680|M.thermoresistible__bu LVLQADAKPENREALVGPVLTGLDAWDLDPRTDLDGA----EAAAALCRS
MMAR_3982|M.marinum_M AALRAETDDGIRRAAR-AALDDLGAFELDVRSGPDDL----LAAAVLCRA
MUL_3843|M.ulcerans_Agy99 AALRAETDDGIRRAAC-AALDDLGAFELDVRSGPDDL----LAAAVLCRA
MAV_1628|M.avium_104 AALRAETDDTVREAAR-TALAEVGAFDLDVRTAPDDL----LAAAVLCQA
Mb3574c|M.bovis_AF2122/97 FEVGALLTEVGRHGAVTPALATLGLGVVPLLELASAE----QQDRFLAGV
Rv3544c|M.tuberculosis_H37Rv FEVGALLTEVGRHGAVTPALATLGLGVVPLLELASAE----QQDRFLAGV
MAB_0594c|M.abscessus_ATCC_199 AVWSTLAELGVTALAVSEKYDGIGAHPVDLVVALEGLGKWAVPGPVVESV
: :. : . :
Mvan_4957|M.vanbaalenii_PYR-1 AGYWALPYPLAERLAKPADLDVDGLVVVGGPRPAAALG-GLDLRWAAVDL
Mflv_1793|M.gilvum_PYR-GCK AGYWAVPYPLAERLAAPTDLDVDGLLVIPATRPSAPVA-GLDLRWAAVDL
MSMEG_5621|M.smegmatis_MC2_155 AGYWALPYPVAERLARPTDLDVDGLIVVADGTPEAALA-GLDLRWAAVTL
TH_0680|M.thermoresistible__bu AGYWALPYPVAERLSRPTDLDVDGLIVVDAAAPLGGVA-GVRLRWATVDL
MMAR_3982|M.marinum_M AGALAIPYPLVEELLS---VDGARLALVNPDLPRIDHG-DLPGSWIAADL
MUL_3843|M.ulcerans_Agy99 AGTVALPYPLVEELLS---IDGARLALVNPDLPRIDHG-DLPGSWIAADL
MAV_1628|M.avium_104 AGAAALPYPLVEELLA---IDGARLTLVNPAAPRIDHG-DLAGDWIAADI
Mb3574c|M.bovis_AF2122/97 AKGGVLTAALNEPGAALPDRPATSFVGGRLSGTKVGVGYAEQADWMLVTA
Rv3544c|M.tuberculosis_H37Rv AKGGVLTAALNEPGAALPDRPATSFVGGRLSGTKVGVGYAEQADWMLVTA
MAB_0594c|M.abscessus_ATCC_199 AVAPVLLSSHEDGAEPSTRLASGELIATVAAPPIAPRALDADIAGLVLIA
* .: . : : . .
Mvan_4957|M.vanbaalenii_PYR-1 DGRRA----LVTGQGVTGP--------------GFVAELELSPVDSDGSR
Mflv_1793|M.gilvum_PYR-GCK DGRRS----TVTGHGEPGP--------------AFVAELELSPVDDAGGP
MSMEG_5621|M.smegmatis_MC2_155 DGTRS----TVTRLGATGP--------------AFTTALDLVEIDAQGAG
TH_0680|M.thermoresistible__bu TGRRA----DVTQVVGAGP--------------GFTARLETTPLDEAGGD
MMAR_3982|M.marinum_M DGARYRPQPAARTAAKLGP--------------FLVPATLGAPEGTVAAS
MUL_3843|M.ulcerans_Agy99 DGARYRPQPAARTAAKLGP--------------FLVPATLGAPEGTVAAS
MAV_1628|M.avium_104 DGNRYRPRPGSRTGAKLGP--------------FLVPATLSAPEGTVPGA
Mb3574c|M.bovis_AF2122/97 DNAVVVVSPTADGVRMVRTPTSNGSDEYVMTMDGVAVADCDILADVAAHR
Rv3544c|M.tuberculosis_H37Rv DNAVVVVSPTADGVRMVRTPTSNGSDEYVMTMDGVAVADCDILADVAAHR
MAB_0594c|M.abscessus_ATCC_199 DDIGIREAQAGAQHESIDATRR-----------VFDVQPKEAGISLDTSR
. . . .
Mvan_4957|M.vanbaalenii_PYR-1 DVALALVLPCWTLLGILDRAVALTVAHVSLRKQFGQTLSSFQGVQFQLTD
Mflv_1793|M.gilvum_PYR-GCK ELALALVLPSWTLLGMLDRALALTVSHVGLRKQFGQTLSSFQGVQFQLTD
MSMEG_5621|M.smegmatis_MC2_155 DVALGLVLGSWTLLGLLDRAVDLTVAHVSLRKQFGQTLSSFQGVQFQLTD
TH_0680|M.thermoresistible__bu DIALALVLSGWTLLGMLDRAIGLTVEHVRLREQFGQPLARFQGVQFQLTD
MMAR_3982|M.marinum_M DIDLHLVLGSWRILGAVQQSLDIVTAHVRTRIQFGKALADFQAVRFCVAD
MUL_3843|M.ulcerans_Agy99 DIDLHLVLGSWRILGAVQQTLDIVTAHVRTRIQLGKALADFQTVRFCVAN
MAV_1628|M.avium_104 DVNLHLVLGAWRILGAVQQSLRIVTDHVQARIQFGKPLADFQAVRFAVAD
Mb3574c|M.bovis_AF2122/97 VNQLALAVMGAYADGLVAGALRLTADYVANRKQFGKPLSTFQTVAAQLAE
Rv3544c|M.tuberculosis_H37Rv VNQLALAVMGAYADGLVAGALRLTADYVANRKQFGKPLSTFQTVAAQLAE
MAB_0594c|M.abscessus_ATCC_199 AIDFGVLAISAQLIGAGQALLDRAVAYAKQRSQFGRPIGSYQAVKHKLAD
: : * : .. :. * *:*:.:. :* * :::
Mvan_4957|M.vanbaalenii_PYR-1 AEVERSGVDILAKHALWSIA-TDQSHVVDDALALRMAAIEAADVVFRVCH
Mflv_1793|M.gilvum_PYR-GCK AEVERSGVDILAKHALWSIA-TDQPQAVDDALALRLAALEAAEVVFRVCH
MSMEG_5621|M.smegmatis_MC2_155 AEVERSGVDILAKHALWGLTRHDTTEVVDDALALRLAAIEAAEVVFRVCH
TH_0680|M.thermoresistible__bu AEVERSGTDILAKHALWSVS-TGQPGALEDALSFRMAALEAAEVVFRVCH
MMAR_3982|M.marinum_M AAVAVRGLAELAKYTISRTESYAARVRSADALLLRLKAADTARQVLRISH
MUL_3843|M.ulcerans_Agy99 AAVAVRGLAELAKYTISRTESYAARVRSADALLLRLKAADTARQVLRISH
MAV_1628|M.avium_104 AAVMVRGLHELAKYTICRPESLPAQVHSADALVLRLKAADTARQVMRTSH
Mb3574c|M.bovis_AF2122/97 VYIASRTIDLVAKSVIWRLA--EDLDAGDDLGVLGYWVTSQAPPAMQICH
Rv3544c|M.tuberculosis_H37Rv VYIASRTIDLVAKSVIWRLA--EDLDAGDDLGVLGYWVTSQAPPAMQICH
MAB_0594c|M.abscessus_ATCC_199 VHIALELARPLVYGAALSLA-DQSPTAARDASAAKVAAAKAAYLAARSAL
. : :. . * . . * . : .
Mvan_4957|M.vanbaalenii_PYR-1 QLHGAVGFCDETTLSWLSRYSLPLRRLPFGLSSTRDHLTRVAGRRGLTGL
Mflv_1793|M.gilvum_PYR-GCK QLHGAAGFCDETTLSWLSRYSQPLRRLPFGLSATRDHLTRLAGRRGLAGL
MSMEG_5621|M.smegmatis_MC2_155 QLHGAVGFCDETTLSWLSRHSQPLRRLPFGISTTRDILTRRVGRRGLTGL
TH_0680|M.thermoresistible__bu QLHGAVGFCDETTLSWLSRYSQPLRRLPLGVSATRAELSRRLGRRGLTGL
MMAR_3982|M.marinum_M QLLGALGFCDESDISVLDRHTQPLIRLPLCAEALAIRLIPDAADGSLETL
MUL_3843|M.ulcerans_Agy99 QLLGALGFCDESDISVLDRHTQPLIRLPLCAEALAIRLIPDAADGSLETL
MAV_1628|M.avium_104 QLLGALGFCDESDVSVLDRHTQPLIRLPLSTEELALRLIPSVADGAFETL
Mb3574c|M.bovis_AF2122/97 HLHGGMGMD---VTYPMHRYYSTIKDLTRLLGGPSHRLELLGARCSLT--
Rv3544c|M.tuberculosis_H37Rv HLHGGMGMD---VTYPMHRYYSTIKDLTRLLGGPSHRLELLGARCSLT--
MAB_0594c|M.abscessus_ATCC_199 QTHGAIGFTAEYDLSLWILKVRALTSAWGTSEWHRARVLEAL--------
: *. *: .: :
Mvan_4957|M.vanbaalenii_PYR-1 FI-----
Mflv_1793|M.gilvum_PYR-GCK YT-----
MSMEG_5621|M.smegmatis_MC2_155 FS-----
TH_0680|M.thermoresistible__bu YA-----
MMAR_3982|M.marinum_M FSAPVSA
MUL_3843|M.ulcerans_Agy99 FSAPVSA
MAV_1628|M.avium_104 FSEPVSA
Mb3574c|M.bovis_AF2122/97 -------
Rv3544c|M.tuberculosis_H37Rv -------
MAB_0594c|M.abscessus_ATCC_199 -------