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M. abscessus ATCC 19977 MAB_0594c (-)

annotation: acyl-CoA dehydrogenase FadE
coordinates: 594454 - 595419
length: 321

KFDLDTQQRDFAASIDAALSVADVPAAARAWAAGNHGPGLAVWSTLAELGVTALAVSEKYDGIGAHPVDL
VVALEGLGKWAVPGPVVESVAVAPVLLSSHEDGAEPSTRLASGELIATVAAPPIAPRALDADIAGLVLIA
DDIGIREAQAGAQHESIDATRRVFDVQPKEAGISLDTSRAIDFGVLAISAQLIGAGQALLDRAVAYAKQR
SQFGRPIGSYQAVKHKLADVHIALELARPLVYGAALSLADQSPTAARDASAAKVAAAKAAYLAARSALQT
HGAIGFTAEYDLSLWILKVRALTSAWGTSEWHRARVLEAL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_0594c--100% (321)acyl-CoA dehydrogenase FadE
M. abscessus ATCC 19977MAB_4336-1e-3131.70% (306) acyl-CoA dehydrogenase FadE
M. abscessus ATCC 19977MAB_0593c-2e-2932.87% (286) acyl-CoA dehydrogenase FadE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3593fadE321e-11164.74% (329) acyl-CoA dehydrogenase FADE32
M. gilvum PYR-GCKMflv_1478-1e-11365.84% (322) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv3563fadE321e-11064.44% (329) acyl-CoA dehydrogenase FADE32
M. leprae Br4923MLBr_00737fadE254e-1530.26% (152) putative acyl-CoA dehydrogenase
M. marinum MMMAR_5052fadE321e-11468.22% (321) acyl-CoA dehydrogenase FadE32
M. avium 104MAV_0598-1e-11366.98% (321) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_6015-1e-11567.39% (322) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_2067fadE321e-11867.38% (325) PROBABLE ACYL-CoA DEHYDROGENASE FADE32
M. ulcerans Agy99MUL_4128fadE321e-11468.22% (321) acyl-CoA dehydrogenase FadE32
M. vanbaalenii PYR-1Mvan_5288-1e-11566.98% (321) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3593|M.bovis_AF2122/97            --------MTMEFALNEQQRDFAASIDAALGAADLPGVVRAWAAGDVAPG
Rv3563|M.tuberculosis_H37Rv         --------MTMEFALNEQQRDFAASIDAALGAADLPGVVRAWAAGDVAPG
MMAR_5052|M.marinum_M               ----------MEFALDEQQRDFAASIDAALAAADLPAAVRAWSAGDVAPG
MUL_4128|M.ulcerans_Agy99           ----------MEFALDEQQRDFAASIDAALAAADLPAAVRAWSAGDVAPG
MAV_0598|M.avium_104                ----------MKFALDEQQRDFAASIDAALGAADLPAAVRAWAVGDTAPG
Mflv_1478|M.gilvum_PYR-GCK          ----------MNFEIDDQQRDFAASIDAALGAADLPAAVRAWGEGDTAPG
Mvan_5288|M.vanbaalenii_PYR-1       ----------MNFEIDEQQRDFAASIDAALGAADVPAAVRAWGEGDTAPG
MSMEG_6015|M.smegmatis_MC2_155      ----------MNFETDEQQRDFAASIDAALGASDVPAAVRAWGEGDTAPG
TH_2067|M.thermoresistible__bu      ----------VNFELDEQQRDFAASIDAALSAADVPAAVRAWAEGDASPG
MAB_0594c|M.abscessus_ATCC_199      ----------MKFDLDTQQRDFAASIDAALSVADVPAAARAWAAGNHGPG
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFP--
                                                *    ::.:: *:* *       * .. .   .     

Mb3593|M.bovis_AF2122/97            RKVWQQLANLGVTALGVAEKFDGLGASPVDLVVALERLGRWCVPG---PV
Rv3563|M.tuberculosis_H37Rv         RKVWQQLANLGVTALGVAEKFDGLGASPVDLVVALERLGRWCVPG---PV
MMAR_5052|M.marinum_M               HKVWEQLANLGVTALTVSEKFDGLGAHPIDLVVALERLGRWCVPG---PV
MUL_4128|M.ulcerans_Agy99           HKVWEQLANLGVTALTVSEKFDGLGAHPIDLVVALERLGRWCVPG---PV
MAV_0598|M.avium_104                RKVWEQLANLGVTALAVPEKFDGIEAEPIDLVVAIERLGRWCVPG---PV
Mflv_1478|M.gilvum_PYR-GCK          RKVWSQLTDLGVTALMVPEKFDGIEAHPVDLVVALERLGRWNVPG---PV
Mvan_5288|M.vanbaalenii_PYR-1       RKVWSQLADLGVTALMVPEKFDGIEAHPVDLVVALERLGRWNVPG---PV
MSMEG_6015|M.smegmatis_MC2_155      RKVWAQLTDLGVTALLVPEKFDGIEAHPTDLVVALERLGYWGVPG---PV
TH_2067|M.thermoresistible__bu      RKIWFQLGELGVTALMVPERFDGIEAHPVDLVVALERLGRWCVPG---PV
MAB_0594c|M.abscessus_ATCC_199      LAVWSTLAELGVTALAVSEKYDGIGAHPVDLVVALEGLGKWAVPG---PV
MLBr_00737|M.leprae_Br4923          EEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPA
                                          *   *..*: *.*.:.*  * .    :.:* :.   ...   *.

Mb3593|M.bovis_AF2122/97            TESIAVAPILLA-HDDRAERSHGLASGELIATVAMPPRVPRAVDADTAGL
Rv3563|M.tuberculosis_H37Rv         TESIAVAPILLA-HDDQAERSHGLASGELIATVAMPPRVPRAVDADTAGL
MMAR_5052|M.marinum_M               AESIAVAPVLLA-DDD---RSAGLACGELIATVALPPHAPRAVDADTAGL
MUL_4128|M.ulcerans_Agy99           AESIAVAPVLLA-DDD---RSAGLACGELIATVALPPHAPRAVDADTAGL
MAV_0598|M.avium_104                VESIAVAPVLLA-GDEHAERCAALASGELIATVALPPQVPRAVDAEEAGL
Mflv_1478|M.gilvum_PYR-GCK          TESIAVAPILLG----DDDRVGALASGELIATVAAPPLVSRAVDADTAGL
Mvan_5288|M.vanbaalenii_PYR-1       AESVAVAPVLLA----DDDRSAALAAGELIATVAAPPLVPRAVNADTAGL
MSMEG_6015|M.smegmatis_MC2_155      TESIAVAPILLA----DDERCGALASGELIATVALPPQVPRAVDADTAGL
TH_2067|M.thermoresistible__bu      TESIAVAPVLLAGSAQEADRYPALAAGELIATVAAPPHTPRAVDADTAGL
MAB_0594c|M.abscessus_ATCC_199      VESVAVAPVLLSSHEDGAEPSTRLASGELIATVAAPPIAPRALDADIAGL
MLBr_00737|M.leprae_Br4923          VNKLGTMGLILR--GSEELKKQVLPSLAAEGAMASYALSEREAGSDAASM
                                    .:.:..  ::*            *..    .::*  .   *  .:: *.:

Mb3593|M.bovis_AF2122/97            VLLAGDGS-------------------------VTEGTPGD---------
Rv3563|M.tuberculosis_H37Rv         VLLAGDGS-------------------------VTEGTPGD---------
MMAR_5052|M.marinum_M               VLVAGESG-------------------------VSEAAVAN---------
MUL_4128|M.ulcerans_Agy99           VLVAGESG-------------------------VCEAAVAD---------
MAV_0598|M.avium_104                VLLADQDG-------------------------VAEAAAGR---------
Mflv_1478|M.gilvum_PYR-GCK          ILLATEGA-------------------------VADAEMGT---------
Mvan_5288|M.vanbaalenii_PYR-1       ILLAEDGS-------------------------VSNASAGA---------
MSMEG_6015|M.smegmatis_MC2_155      ILLAQDGQ-------------------------VHDGSAGA---------
TH_2067|M.thermoresistible__bu      ILLAADGQ-------------------------VQDATAGA---------
MAB_0594c|M.abscessus_ATCC_199      VLIADDIG-------------------------IREAQAGA---------
MLBr_00737|M.leprae_Br4923          RTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVH
                                       *                             : :   .          

Mb3593|M.bovis_AF2122/97            ---CHRSVDPSRRLYEVAAS-------------GQAWRAPKDV----VAR
Rv3563|M.tuberculosis_H37Rv         ---CHRSVDPSRRLYEVAAS-------------GQAWRAPKDV----VAR
MMAR_5052|M.marinum_M               ---CHESIDPSRRSYDVTAT-------------GATWQAD-------VKR
MUL_4128|M.ulcerans_Agy99           ---CHESIDPSRRSYDVTAT-------------GAAWQAD-------VKR
MAV_0598|M.avium_104                ---QHASVDPSRRLYDVEPT-------------GDRWQAD-------VGR
Mflv_1478|M.gilvum_PYR-GCK          ---QHESVDPARKLFEVTAS-------------GEARAAD-------VER
Mvan_5288|M.vanbaalenii_PYR-1       ---EHESVDPSRKLFEVSAY-------------GDRKAAD-------VAR
MSMEG_6015|M.smegmatis_MC2_155      ---SHESVDPTRKLFDVAAS-------------GDARTAD-------TAT
TH_2067|M.thermoresistible__bu      ---AHESVDPSRKLFDVNGT-------------GVTHSAD-------TGR
MAB_0594c|M.abscessus_ATCC_199      ---QHESIDATRRVFDVQPK-------------EAGISLD-------TSR
MLBr_00737|M.leprae_Br4923          KDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALA
                                          *:.. .:   :                              .  

Mb3593|M.bovis_AF2122/97            AYEFGALATAAQLVGAGQALLEAAVNYAKQRTQFGRAIGSYQAIKHKLAD
Rv3563|M.tuberculosis_H37Rv         AYEFGALATAAQLVGAGQALLEAAVNYAKQRTQFGRAIGSYQAIKHKLAD
MMAR_5052|M.marinum_M               AYEFGALATAAQLIGAAEALLDATVDYAKQRTQFGRVIGSYQAIKHKLAD
MUL_4128|M.ulcerans_Agy99           AYEFGALATAAQLIGAAEALLDATVDYAKQRTQFGRVIGSYQAIKHKLAD
MAV_0598|M.avium_104                GYEFGALATAAQLVGAAEALRDAAVDYAKQRTQFGRVIGSYQAIKHKLAD
Mflv_1478|M.gilvum_PYR-GCK          AFEFGALATAAQLVGAAQAMLDASVEYAKQRSQFGTIIGTYQAIKHKLAD
Mvan_5288|M.vanbaalenii_PYR-1       AFEFGALATSALLVGAAQAMLDASVEYAKQRSQFGTVIGTYQAIKHKLAD
MSMEG_6015|M.smegmatis_MC2_155      AYEFGVLATAAQLVGAGQAMLDQAVEYAKQRTQFGRVIGSYQAIKHKLAD
TH_2067|M.thermoresistible__bu      AFEFGALGTAAQLIGAAQAMLDMSVDYAKQRSQFGNVIGSYQAIKHKLAD
MAB_0594c|M.abscessus_ATCC_199      AIDFGVLAISAQLIGAGQALLDRAVAYAKQRSQFGRPIGSYQAVKHKLAD
MLBr_00737|M.leprae_Br4923          TLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLAD
                                      :.     .*  :* .:.  : :: *:*:*.***  *.::*:::. ***

Mb3593|M.bovis_AF2122/97            VHIAIELACPLVYGAAVSLEP----------RDVSAAKAAASEAALLAAR
Rv3563|M.tuberculosis_H37Rv         VHIAIELACPLVYGAAVSLEP----------RDVSAAKAAASEAALLAAR
MMAR_5052|M.marinum_M               VHIAIELARPLVHGAALSLQP----------RDVSAAKVAAGDAALLAAR
MUL_4128|M.ulcerans_Agy99           VHIAIELARPLVHGAALSLQP----------RDVSAAKVAAGGAARLAAR
MAV_0598|M.avium_104                VHIAIELARPLVYGAALTLQP----------RDVSAAKAAASDAALLAAR
Mflv_1478|M.gilvum_PYR-GCK          VLIAVELARPLVYGAALSLAD----GSQDTARDVSAAKVAAADAALLAAR
Mvan_5288|M.vanbaalenii_PYR-1       VLIAVELARPLVYGAALSLAD----GSTDTGRDVSAAKVAAADAALLAAR
MSMEG_6015|M.smegmatis_MC2_155      VHIAVELARPLVYGAALSLAD----GSSDTARDVSAAKVAAADAALLAAR
TH_2067|M.thermoresistible__bu      VHIAVELARPLVYGAALSLAGRKEEASPDTARDVSAAKVAAGEAALLAAR
MAB_0594c|M.abscessus_ATCC_199      VHIALELARPLVYGAALSLAD----QSPTAARDASAAKVAAAKAAYLAAR
MLBr_00737|M.leprae_Br4923          MAMKVEAARLIVYAAAARAER----GEPDLGFISAASKCFASDIAMEVTT
                                    : : :* *  :*:.**                  :*:*  *.  *  .: 

Mb3593|M.bovis_AF2122/97            SALQTHGAIGFTCEHDLSLWLLRVQALHSAWGTPQEHRRRVLEAL--
Rv3563|M.tuberculosis_H37Rv         WALQTHGAIGFTCEHDLSLWLLRVQALHSAWGTPQEHRRRVLEAL--
MMAR_5052|M.marinum_M               SALQTHGAIGFTQEHDLSLWLLRVQALRSAWGTPEVHRRRVLEAL--
MUL_4128|M.ulcerans_Agy99           SALQTHGAIGFTQEHDLSLWLLRVQALRSAWGTPEVHRRRVLEAL--
MAV_0598|M.avium_104                SALQTHGAIGFTQEHDLSLLLLRVQAVRSAWGPPQVHRRRVLEAL--
Mflv_1478|M.gilvum_PYR-GCK          SSLQTHGAIGFTQEHDLSLLLLRVQALRPAWGDPTWHRHRVLEALTK
Mvan_5288|M.vanbaalenii_PYR-1       SSLQTHGAIGFTQEHDLSLLLLRVQALRPAWGDPTWHRRRVLEALTK
MSMEG_6015|M.smegmatis_MC2_155      SALQTHGAIGFTQEHDLSLLLLRVQALRPAWGDPALHRRRVLEGLS-
TH_2067|M.thermoresistible__bu      SSLQTHGAIGFTAEHDLSLWLLRVQALRTAWGDPTTHRRRVLEGIS-
MAB_0594c|M.abscessus_ATCC_199      SALQTHGAIGFTAEYDLSLWILKVRALTSAWGTSEWHRARVLEAL--
MLBr_00737|M.leprae_Br4923          DAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
                                     ::* .*. *:* :. :.  :  .:      *    :*  : ..: