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M. vanbaalenii PYR-1 Mvan_5207 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 5573719 - 5574828
length: 369

MDFKTTEASEDLGGLVRTITESVCTPEHQRELDGLRPEAGGRFDRDLWGKLIDADILSTTSPESLGGGGF
GVLEEVAVLVALGRQLAAVPYLESVMLAAGALATFGSASLQQDWAAQAIKGEKVLAVAFDGEMGEGPVLA
QGSGDGYTLTGSRTQVAFGVNADAFLVPAETDSGTAVFLVGSADDGVAVTALDTTGHGSVAGLQLQGVAI
GSDRRVGGPEVLDWLVTRHALGRSAYQLGVLERALELTASYAREREQFDRPIGSFQAVSSRLADGYIDIK
GLRLTLTQAAWRLSEDLPADLDVASAAFWAAEAGHRVAHTTVHVHGGVGIDIDHPVHRYFLAAKQTEFAV
GGATGQLLRIGRELADTPA

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_5207 - - 100% (369) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_0393 - 3e-33 33.43% (341) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_5257 - 1e-31 30.72% (319) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3535 fadE27 1e-153 72.41% (377) acyl-CoA dehydrogenase FADE27
M. gilvum PYR-GCK Mflv_1550 - 0.0 86.18% (369) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3505 fadE27 1e-152 72.41% (377) acyl-CoA dehydrogenase FADE27
M. leprae Br4923 MLBr_00737 fadE25 4e-18 26.37% (383) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_4159 - 1e-140 68.02% (369) acyl-CoA dehydrogenase
M. marinum M MMAR_4993 fadE27 1e-149 71.82% (369) acyl-CoA dehydrogenase FadE27
M. avium 104 MAV_0651 - 1e-152 73.71% (369) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_5907 - 1e-161 77.17% (368) acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_3575 - 1e-93 67.05% (264) PUTATIVE acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_4068 fadE27 1e-149 71.82% (369) acyl-CoA dehydrogenase FadE27

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_5207|M.vanbaalenii_PYR-1       ----------MDFKTTEASEDLGGLVRTITESVCTPEHQRELDGLRPEAG
Mflv_1550|M.gilvum_PYR-GCK          ----------MDFTTTEASEDLGGLVRTITESVCTPEHQRELDGLGPDAG
Mb3535|M.bovis_AF2122/97            ----------MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKL----E
Rv3505|M.tuberculosis_H37Rv         ----------MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKL----E
MMAR_4993|M.marinum_M               ----------MDFSTTEAAQDLGGLVDTIVDAVCTPEHQRQLDRL----E
MUL_4068|M.ulcerans_Agy99           ----------MDFSTTEAAQDLGGLVATIVDAVCTPEHQRQLDGL----E
MAV_0651|M.avium_104                ----------MDFTTTEAAHDLGNLVDTIVDSVCTPEHQRELDGL----D
MSMEG_5907|M.smegmatis_MC2_155      ----------MDFTTTEAAADLGGLVRTITESVCTPEHQRELDGLP----
MAB_4159|M.abscessus_ATCC_1997      ----------MDFSLTEAQTDLAGLTRTIASTISTPERQKELDKQ----D
TH_3575|M.thermoresistible__bu      ----------MDFTSTEAAEELGGLVRTITESVCTHEHQRELDKL----E
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAP-HAADVDQR-----
                                                *. .*   :*     ::..   :  :  ::*       

Mvan_5207|M.vanbaalenii_PYR-1       GRFDRDLWGKLIDADILSTTSPESLGGGGFGVLEEVAVLVALGRQLAAVP
Mflv_1550|M.gilvum_PYR-GCK          GRFDKTLWSKLIDADVLSTTAPESLGGGGFGVLEEVAVLVALGRQLAAVP
Mb3535|M.bovis_AF2122/97            QRFDRELWRKLIDAGILSSAAPESLGGDGFGVLEQVAVLVALGHQLAAVP
Rv3505|M.tuberculosis_H37Rv         QRFDRELWRKLIDAGILSSAAPESLGGDGFGVLEQVAVLVALGHQLAAVP
MMAR_4993|M.marinum_M               QRFDRELWRKLIDSDILSSAAATQVGGDGFGVLEQVAILVALGHQLAAVP
MUL_4068|M.ulcerans_Agy99           QRFDRELWRKLIDSDILSSAAATQVGGDGFGVLEQVAILVALGHQLAAVP
MAV_0651|M.avium_104                QRFDRDLWAKLIDAGILSSASATSLGGDGFGALEQIAILVALGHQLAAVP
MSMEG_5907|M.smegmatis_MC2_155      ERFDRDLWAKLVEADILSAAAPESVGGGGFGVLEQTSVLTALGRQLAAVP
MAB_4159|M.abscessus_ATCC_1997      SRFDRQLWTKLAEADILSTAAPESVGGAGFGVLEQSSILVELGRELAAVP
TH_3575|M.thermoresistible__bu      QRFDTELWAKLIDADVLSTAAPESIGGGGFGVLEQVAVLVALGRQLGAVP
MLBr_00737|M.leprae_Br4923          ARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASAS
                                     **       *  :.. :   . . ** * . :    ::  :.:  .:..

Mvan_5207|M.vanbaalenii_PYR-1       YLESV-MLAAGALATFGSASLQQDWAAQAIKGEKVLAVAFD-----GEMG
Mflv_1550|M.gilvum_PYR-GCK          YLESV-VLGAGALARFGDDGLQQQWAAPAVTGDKVLTVALD-----GEMG
Mb3535|M.bovis_AF2122/97            YLESV-VLAAGALARFGSPELQQGWGVSAVSGDRILTVALD-----GEMG
Rv3505|M.tuberculosis_H37Rv         YLESV-VLAAGALARFGSPELQQGWGVSAVSGDRILTVALD-----GEMG
MMAR_4993|M.marinum_M               YLESV-VLAAGALARFGSEELQQSWGAAAVGGEKILAVALD-----AEMG
MUL_4068|M.ulcerans_Agy99           YLESV-VLAAGALARFGSEELQQSWGAAAVGGEKILAVALD-----AEMG
MAV_0651|M.avium_104                YLESV-VLGAGALARFGTEELQQGWGVPAVSGEKTLTVALD-----PEMG
MSMEG_5907|M.smegmatis_MC2_155      YLESV-VAAAGAIAEFGSDAQRAEWGAPAVAGSKILTVALD-----GEMG
MAB_4159|M.abscessus_ATCC_1997      YLESV-VLAAGALAAFGSEAMRNDWAAPAVAGKKVLTIALE-----GEPG
TH_3575|M.thermoresistible__bu      YLESV-VLGAGALAEFGSDAQREQWAAPAVGGQRILTAALE-----GETG
MLBr_00737|M.leprae_Br4923          LIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAA
                                     : :*   .: .:   *    :              : *:.      : .

Mvan_5207|M.vanbaalenii_PYR-1       EGPVLAQGSGD-GYTLTGSRTQVAFGVNADAFLVPAETDS-----GTAVF
Mflv_1550|M.gilvum_PYR-GCK          EGPVRATTTAD-GVTLTGTRTQVPFAVGADAFLVPAETDS-----GVAVF
Mb3535|M.bovis_AF2122/97            EGPVQAAGTGH-GYRLTGTRTQVGYGPVADAFLVPAETDS-----GAAVF
Rv3505|M.tuberculosis_H37Rv         EGPVQAAGTGH-GYRLTGTRTQVGYGPVADAFLVPAETDS-----GAAVF
MMAR_4993|M.marinum_M               EGPVQAARSGA-GFRLTGTRTQVGYGPVADAFLVPAETDS-----GTVVF
MUL_4068|M.ulcerans_Agy99           EGPVQAARSGA-GFRLTGTRTQVGYGPVADAFLVPAETDS-----GTVVF
MAV_0651|M.avium_104                EGPVQAVSAGA-GYRLTGTRTQVGFGPVADAFLVPAETDS-----GTAVF
MSMEG_5907|M.smegmatis_MC2_155      QGPVQAQADGD-DHRLTGSRTLVSYGPVADAYLVPAETGS-----GVSVF
MAB_4159|M.abscessus_ATCC_1997      EGPVAARTEGT-GYVLTGNRVLVPFGVEADAYLVPAETET-----GTAVF
TH_3575|M.thermoresistible__bu      EGPVRAEVNADSGHTLTGTRTLVRFGPVADGFLVPAETDS-----GTRVF
MLBr_00737|M.leprae_Br4923          SMRTRAKADGD-DWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAF
                                    .  . *   .  .  *.* :  :  .  :  : * * * .     *  .*

Mvan_5207|M.vanbaalenii_PYR-1       LVGSADDGVAVTALDTTG--HGS-VAGLQLQGVAIGSDRRVGGPE-VLDW
Mflv_1550|M.gilvum_PYR-GCK          LVAAADAGVTVTPLDTTG--HGS-VAALDLQGVGITGDRRVGGSE-VLDW
Mb3535|M.bovis_AF2122/97            LVAAGDPGVAVTALATTG--LGS-VGHLELNGAKVDAARRVGGTD-VVVW
Rv3505|M.tuberculosis_H37Rv         LVAAGDPGVAVTALATTG--LGS-VGHLELNGAKVDAARRVGGTD-VAVW
MMAR_4993|M.marinum_M               LVAADDPGVSVTALQTTG--LGS-VGHLALDGTEVDAARGIGGSD-VTAW
MUL_4068|M.ulcerans_Agy99           LVAADDPGVSVTALQTTG--LGS-VGHLALDGTEVDAARGIGGSD-VTAW
MAV_0651|M.avium_104                LVAADDPGVTVTALETTG--LGS-VGHLALDGTQVDGTRQVGGAE-VAAW
MSMEG_5907|M.smegmatis_MC2_155      IVAADDAGVTETSLNTTG--KGS-VAHLDLQDVAVGADRVLGGTQ-VAEW
MAB_4159|M.abscessus_ATCC_1997      LVSADDAGVTQQALHTTG--KDS-SAELILSEVPVPAERKVGGAE-VVEW
TH_3575|M.thermoresistible__bu      LVAADDPGVTVTALNTTG--RGS-VGRLELAGTVLPPDRTVGADEAALRW
MLBr_00737|M.leprae_Br4923          IVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPG--TGF
                                    :*   * *.:  .  ..    .*    * :    :   * :*       :

Mvan_5207|M.vanbaalenii_PYR-1       LVTRHALGRS-----AYQLGVLERALELTASYAREREQFDRPIGSFQAVS
Mflv_1550|M.gilvum_PYR-GCK          LVTRNALARS-----AYQLGVVERALELTAQYAREREQFDRPIGSFQAVS
Mb3535|M.bovis_AF2122/97            LGTLSTLSRT-----AFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVG
Rv3505|M.tuberculosis_H37Rv         LGTLSTLSRT-----AFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVG
MMAR_4993|M.marinum_M               LRTINTLGRS-----AFQLGVLERGLRMTAEYARTREQFDRPIGSFQAVG
MUL_4068|M.ulcerans_Agy99           LRTINTLGRS-----AFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVG
MAV_0651|M.avium_104                LGTLGTLGRA-----AFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVS
MSMEG_5907|M.smegmatis_MC2_155      LTTRVTLGRT-----AYQLGVLERALELTASYAREREQFDRPIGSFQAVS
MAB_4159|M.abscessus_ATCC_1997      LRLRESLGHS-----AYQLGVLERALELTADYARTREQFGKPIGGFQAVA
TH_3575|M.thermoresistible__bu      IKIRNILGHS-----AFQLGVLERALEMTAAYAREREQFDRPLX---XXA
MLBr_00737|M.leprae_Br4923          KTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQ
                                          * ::     *  :*: : .*  :  *:: *:**...:       

Mvan_5207|M.vanbaalenii_PYR-1       SRLADGYIDIKGLRLTLTQAAWRLSED--------LPADLDVASAAFWAA
Mflv_1550|M.gilvum_PYR-GCK          SRLADGYIDIKGLRLTVTQAAWRVSED--------LPADVDVASAAFWAA
Mb3535|M.bovis_AF2122/97            QRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAA
Rv3505|M.tuberculosis_H37Rv         QRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAA
MMAR_4993|M.marinum_M               QRLADGYIDVKGLRLTLTQAAWRVSED--------LPAEIDVASAGFWAA
MUL_4068|M.ulcerans_Agy99           QRLADGYIDVKGLRLTLTQAAWRVSED--------LPAEIDVASAGFCAA
MAV_0651|M.avium_104                QRLADGYIDVKGLRLTLTQAAWRVSED--------LPAEVDVATAAFWAA
MSMEG_5907|M.smegmatis_MC2_155      SRLADGYIDVKGLRLTLTQAAWRLSED--------LPADVDVASAAFWAA
MAB_4159|M.abscessus_ATCC_1997      QRLADGYIDVKGLCLTLWQAAWRVSED--------LPSDVDVATAKFWAA
TH_3575|M.thermoresistible__bu      GGCAGGGVPAG------------------------RPGHRGAAVGGGRAG
MLBr_00737|M.leprae_Br4923          FMLADMAMKVEAARLIVYAAAARAERGE-------PDLGFISAASKCFAS
                                       *.  :                                  * .   *.

Mvan_5207|M.vanbaalenii_PYR-1       EAGHRVAHTTVHVHGGVGIDIDHPVHRYFLAAKQTEFAVGGATGQLLRIG
Mflv_1550|M.gilvum_PYR-GCK          EAGHRVAHTAVHVHGGVGIDIDHPVHRYFLAAKQTEFAVGGATGQLLRIG
Mb3535|M.bovis_AF2122/97            EAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQLRRIG
Rv3505|M.tuberculosis_H37Rv         EAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQLRRIG
MMAR_4993|M.marinum_M               EAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKEAEFALGGATTALRQIG
MUL_4068|M.ulcerans_Agy99           EAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKEAEFALGGATTALRQIG
MAV_0651|M.avium_104                DAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKQAEFALGGATGQLRRIG
MSMEG_5907|M.smegmatis_MC2_155      EAGHRVAHTAVHVHGGVGIDMDHPVHRYFLAAKQSEFALGSATGQLLRIG
MAB_4159|M.abscessus_ATCC_1997      DAGHRVAHTAVHVHGGVGIDEDHPVHRYFLAAKRGEFASGSATEQLRRIG
TH_3575|M.thermoresistible__bu      PSG-RTAHPGRPGH----------LRRRARDGVQDAAGRCADGGGARRW-
MLBr_00737|M.leprae_Br4923          DIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMS
                                      . ..:      .          :.*    .                  

Mvan_5207|M.vanbaalenii_PYR-1       RELADTPA
Mflv_1550|M.gilvum_PYR-GCK          RELADTPA
Mb3535|M.bovis_AF2122/97            RELAETPA
Rv3505|M.tuberculosis_H37Rv         RELAETPA
MMAR_4993|M.marinum_M               RELAETPA
MUL_4068|M.ulcerans_Agy99           RELAETPA
MAV_0651|M.avium_104                RELAETPA
MSMEG_5907|M.smegmatis_MC2_155      RELADTPV
MAB_4159|M.abscessus_ATCC_1997      RELADTPA
TH_3575|M.thermoresistible__bu      --------
MLBr_00737|M.leprae_Br4923          RALLR---

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_5207	-	-	100% (369)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_0393	-	3e-33	33.43% (341)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_5257	-	1e-31	30.72% (319)	acyl-CoA dehydrogenase domain-containing protein