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VELRQVEHFLAVAGEMSFTRAAERVHVVQSALSTSIAKLERELDVDLFDRSRQQIRLTAAGDRFLTHAYE VLRVSRAAADSVGEFRQSLMGTVEFGSLISFGPMDVGRALGDFHRAHPFVRLRLRLSQAGASAYLGALVE GSLDLALVSVPDRFPRQLEMRLLFAEPMVFVCRGDHAFADRGTLDLADVALEDIVGFPPEFGLRRLMEGA FRAVGVAPRTQYEVPAGFAAIADLVRNGLGTAFMPASEARRFSDLRPVELADHVLWQVYLASRPVDHLTP ATARLADALLDAAADARAQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0328 | - | - | 100% (299) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 4e-37 | 35.29% (289) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 3e-23 | 33.07% (251) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0121 | oxyS | 7e-20 | 28.67% (293) | oxidative stress response regulatory protein OXYS |
| M. gilvum PYR-GCK | Mflv_3565 | - | 1e-35 | 34.03% (288) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0117 | oxyS | 7e-20 | 28.67% (293) | oxidative stress response regulatory protein OXYS |
| M. leprae Br4923 | MLBr_02663 | oxyS | 2e-18 | 29.00% (269) | putative LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3308 | - | 3e-92 | 56.31% (293) | LysR family transcriptional regulator |
| M. marinum M | MMAR_0317 | oxyS | 1e-20 | 28.24% (301) | oxidative stress response regulatory protein OxyS |
| M. avium 104 | MAV_1538 | - | 4e-24 | 29.11% (292) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_6849 | - | 1e-119 | 73.58% (299) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 4e-15 | 26.19% (294) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4805 | oxyS | 8e-19 | 30.21% (235) | oxidative stress response regulatory protein OxyS |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0328|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6849|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3308|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3565|M.gilvum_PYR-GCK --------------------------------------------------
Mb0121|M.bovis_AF2122/97 --------------------------------------------------
Rv0117|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0317|M.marinum_M MKLLGAPKINPELTLAQIPGSDSLVVIPIPRTSGLARRAAPAVQPRCGVT
MUL_4805|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02663|M.leprae_Br4923 --------------------------------------------------
MAV_1538|M.avium_104 --------------------------------------------------
TH_3504|M.thermoresistible__bu --------------------------------------------------
Mvan_0328|M.vanbaalenii_PYR-1 ---------------------------------------------MELRQ
MSMEG_6849|M.smegmatis_MC2_155 ---------------------------------------------MELRQ
MAB_3308|M.abscessus_ATCC_1997 ---------------------------------------------MELRQ
Mflv_3565|M.gilvum_PYR-GCK ---------------------------------------------MELRQ
Mb0121|M.bovis_AF2122/97 ---------------------------------------------MLFRQ
Rv0117|M.tuberculosis_H37Rv ---------------------------------------------MLFRQ
MMAR_0317|M.marinum_M RTAQWRADLVATVQDLAAQSGTGGRQRSGGGGSLSESVPMTEEVSVLFRQ
MUL_4805|M.ulcerans_Agy99 ---------------------------------------------MLFRQ
MLBr_02663|M.leprae_Br4923 ---------------------------------------------MLFRQ
MAV_1538|M.avium_104 ---------------------------------------------MAVGD
TH_3504|M.thermoresistible__bu ----------------------------------------VPSPKIDLRR
: .
Mvan_0328|M.vanbaalenii_PYR-1 VEHFLAVAGEMSFTRAAERVHVVQSALSTSIAKLERELDVDLFDRSRQQI
MSMEG_6849|M.smegmatis_MC2_155 LEHFVAVAEELSFTRAAQRVHVVQSALSSSVAKLERELGVELLDRTRQQI
MAB_3308|M.abscessus_ATCC_1997 LEHFVAVAGEMSFSRAVQRAHVVQSALSTSVGKLEKELGVELFDRTRQQI
Mflv_3565|M.gilvum_PYR-GCK LEYFVAIVEEGGFTRAASRERVAQPAVSAQIRRLERSVGQPLLTRTSREV
Mb0121|M.bovis_AF2122/97 LEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFE
Rv0117|M.tuberculosis_H37Rv LEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFE
MMAR_0317|M.marinum_M LEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFE
MUL_4805|M.ulcerans_Agy99 LEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELHVTLINRGHSFE
MLBr_02663|M.leprae_Br4923 LEYFVAVAQERHFARAAERCYVSQPALSSAIAKLERELNVTLINRGHSFE
MAV_1538|M.avium_104 YEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRLGVALFDRHGRRL
TH_3504|M.thermoresistible__bu LAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDVGADLFTRDGRRI
*:::. .: *. : * ::: : **. : *: *
Mvan_0328|M.vanbaalenii_PYR-1 RLTAAGDRFLTHAYEVLRVSRAAADSVGEFRQSLMGTVEFGSLISFGPMD
MSMEG_6849|M.smegmatis_MC2_155 SLTAAGDRFRTYALGVLREARNAVDVVSEFRGELSGTVDFGSLISFGPMD
MAB_3308|M.abscessus_ATCC_1997 RLTPAGELFHTHATRVIQAARYAKDSIGNFRGELTGTVDLGALITFGPLD
Mflv_3565|M.gilvum_PYR-GCK RLTRAGEALLPHARAALAAVRDGRAAVDDVAGLLRGSVAIG-TVTLHPMN
Mb0121|M.bovis_AF2122/97 GLTREGERLVVWAKRILAEHAAFKAEVDAVRSGITGTLRLG-TVPTASTT
Rv0117|M.tuberculosis_H37Rv GLTREGERLVVWAKRILAEHAAFKAEVDAVRSGITGTLRLG-TVPTASTT
MMAR_0317|M.marinum_M GLTPEGERLVVWAKRIIAEHDAFKAEVDAVRSGITGTLRLG-TVPSASTT
MUL_4805|M.ulcerans_Agy99 GLTPEGERLVVWAKRIIAEHDAFKAEVDAVRSGITGTLRLG-TVRSASTT
MLBr_02663|M.leprae_Br4923 GLTPEGERLVVWAKRILAEHDAFKAEVHAVRSGITGTLRLG-TVPTASTT
MAV_1538|M.avium_104 SLNTYGRIFYEHARRAQLELDSARRAIADLADPAVGEIRLAYLSSFGSTV
TH_3504|M.thermoresistible__bu SLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAHYVIGHTPALSGAE
*. * : . : . :.
Mvan_0328|M.vanbaalenii_PYR-1 VGRALGDFHRAHPFVRLRLRLSQAGASAYLGALVEGSLDLALVSVP-DRF
MSMEG_6849|M.smegmatis_MC2_155 VARALGDFHRAHPHVRLRLRLSQSGASAYLSGLIEGSLDLALISVP-NRF
MAB_3308|M.abscessus_ATCC_1997 VPKMLGQFHREYPLVQIRLRQSQSGSNAYLSAIADGTLDLALVSAP-DRF
Mflv_3565|M.gilvum_PYR-GCK VAHLIAEFHADHPDVEITLG--TATSDVLIAELGDGRLDLAIVSIAVDED
Mb0121|M.bovis_AF2122/97 ASLVLSAFCSAHPLAKVQVCSRLAATELYR-RLREFELDAVIVHPE-TQD
Rv0117|M.tuberculosis_H37Rv ASLVLSAFCSAHPLAKVQVCSRLAATELYR-RLREFELDAVIVHPE-TQD
MMAR_0317|M.marinum_M ASLVLSDFCSAHPLVKAQICSRLAVTELYR-RLRDFELDAAIVYTS-SDD
MUL_4805|M.ulcerans_Agy99 ASLVLSDFCSAHPLVKAQICSRLAVTELYR-RLRDFERDAAIVYTS-SDD
MLBr_02663|M.leprae_Br4923 ASLVLSAFCSEHPLIKVQICSRLPVTELHR-RLGDFELDAVIVHSA-PDD
MAV_1538|M.avium_104 VPRLIARFKESSPRVTFTLEEGAAESIADR--VRSGGVDIGVVSPR--PV
TH_3504|M.thermoresistible__bu AYALIEPAVTAYPSTSFTLR--QLYPDALTDAVFDGTVQLGLRRGV--VP
. : * : . : . : :
Mvan_0328|M.vanbaalenii_PYR-1 PRQLEMRLLFAEPMVFVCRGDHAFADRGTLDLADVALEDIVGFPPEFG--
MSMEG_6849|M.smegmatis_MC2_155 PPQLEMRLLFEEPMVFVCRPDHPVARRRRVSLDVLGTEDLVGFPPEFG--
MAB_3308|M.abscessus_ATCC_1997 PAGIQMRLLCQEPMMFVCRPDHRLAQRRHVTVTELVDEHLIGFPPQFS--
Mflv_3565|M.gilvum_PYR-GCK LPGLEVAVITDEAVEAAVADGHPLAHRRSLSLEQLSRHPLISLPAGTG--
Mb0121|M.bovis_AF2122/97 SDDVDLVPLYEEQYVLLSPADMLPPGTSTLVWRDAAQLPLALLTADMR--
Rv0117|M.tuberculosis_H37Rv SDDVDLVPLYEEQYVLLSPADMLPPGTSTLVWRDAAQLPLALLTADMR--
MMAR_0317|M.marinum_M GHDVDLVPLYEERYVLLAPPEMLPPGVSTLSWLDAAQLPLALLSSDMR--
MUL_4805|M.ulcerans_Agy99 GHDVDLVPLYEERYVLLAPPEMLPPGVSTLSWLDAAQLPLALLSSDMR--
MLBr_02663|M.leprae_Br4923 THAVDLVPLYHEHYVLVSPADMLPPGASVLAWPEASQLPLALLTPDMR--
MAV_1538|M.avium_104 ERTLAWRSLFRQRLGVAVPDGHRFARGAAVSMVDLADEPFVTMHPGFG--
TH_3504|M.thermoresistible__bu TPELATAVIGYHRVRVAFVDSHPLAARESVDITELAREQVALWAPPGTSY
: : . . : . .
Mvan_0328|M.vanbaalenii_PYR-1 LRRLMEGAFRAVGVAPRTQYEVPAGFAAIADLVRNGLGTAFMPASEARRF
MSMEG_6849|M.smegmatis_MC2_155 LRRLTDDAFRAAGVQARTQYEVPAGFAAVADLVANGLGTALMPASEARRL
MAB_3308|M.abscessus_ATCC_1997 LRRIVEDAFTAAGVTAFTPHEVALEYAIAASLVHHGLGTIFMPASEAAQF
Mflv_3565|M.gilvum_PYR-GCK LRTRLDTACAAAGLRPRIAFEATS-PAELAELARHGLGVAILPQSMARGG
Mb0121|M.bovis_AF2122/97 DRQVIDAAFADHAVSAIPQVETDS-VASLFAQVATGNWASIVPHTWLWAM
Rv0117|M.tuberculosis_H37Rv DRQVIDAAFADHAVSAIPQVETDS-VASLFAQVATGNWASIVPHTWLWAM
MMAR_0317|M.marinum_M DRQIIDAAFADHAITVSPQVETDS-VASLFAQVATGNSASIVPHTWLWTT
MUL_4805|M.ulcerans_Agy99 DRQIIDAAFADHAITVSPQVETDS-VASLFAQVATGNSASIVPHTWLWTT
MLBr_02663|M.leprae_Br4923 DRQLIDRAFAGHAITATPQVETDS-VASLFAQVATGNWACIVPHTWLWTT
MAV_1538|M.avium_104 MRRLLDELCAAAQFRPRVALQAPN-LTTAASLVAAGLGISLVPIDGSSYP
TH_3504|M.thermoresistible__bu YSDFLMGACRRAGFEPDYVVSRVQGAATVAAPLTTG-GIAFVTAAAG---
. . : * ::.
Mvan_0328|M.vanbaalenii_PYR-1 SDLR--------PVELADHVLWQVYLASRPVDHLTPATARLADALLDAAA
MSMEG_6849|M.smegmatis_MC2_155 GNLT--------AVTLETAVIWQVYLASPPADRMTPATARLADTLLDEAV
MAB_3308|M.abscessus_ATCC_1997 PHLR--------ALAVRPAIIWKIYLASAEQSQLGPASAQLAEHLVASAH
Mflv_3565|M.gilvum_PYR-GCK SGLH--------ALRLAPELRGRLVWAWR-ADGANPAARVLGERARAMAV
Mb0121|M.bovis_AF2122/97 PMSGPTGGEIRAVELVDPVLKAQIALATNALGPGSPVARALITCAQALAL
Rv0117|M.tuberculosis_H37Rv PMSGPTGGEIRAVELVDPVLKAQIALATNALGPGSPVARALITCAQALAL
MMAR_0317|M.marinum_M PAGG----EIRPVQLVSPVVKAQVALATSSTGPGSPVARALMTSAQGLAL
MUL_4805|M.ulcerans_Agy99 PGR-----------------------------------------------
MLBr_02663|M.leprae_Br4923 PIGA----EIRAVEMVDPVLKADVALATNSAGPGSPVARALVASAKQLAL
MAV_1538|M.avium_104 SGVS-------VKPLADADAYRDVGMIWDSGRPLPRSARDFIAGAAAVGH
TH_3504|M.thermoresistible__bu -----------------PTMNGRVQVVDLTPPLLVPVQALWQRHTLSAIR
Mvan_0328|M.vanbaalenii_PYR-1 DARAQ-----------
MSMEG_6849|M.smegmatis_MC2_155 RARARRYGTRPGIDHP
MAB_3308|M.abscessus_ATCC_1997 AQTNSPKT--------
Mflv_3565|M.gilvum_PYR-GCK SPGSGAPAVVPGA---
Mb0121|M.bovis_AF2122/97 NEFFDTQLRGITRRR-
Rv0117|M.tuberculosis_H37Rv NEFFDTQLRGITRRR-
MMAR_0317|M.marinum_M DEFFQTRLMEISRRR-
MUL_4805|M.ulcerans_Agy99 ----------------
MLBr_02663|M.leprae_Br4923 NEFFEAQLAGITRRR-
MAV_1538|M.avium_104 GGW-------------
TH_3504|M.thermoresistible__bu DRILEGLG--------