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MNTIELSIGGMTCASCAARVEKKLNKLDGVTATVNFATEKARVAFGDEVSPGQLVSAVESAGYQAELPER PDEPAEPTDDPTAALKRRLLICVALSVPVIAMAMVPVLQFTYWQWLSLTLAAPVVVWGAWPFHQAAWTNL RHGTATMDTLISIGTLAALGWSIYALFWGTAGIPGMTHPFELTIARTDGTSNIYLEAAAGVTTFILAGRY FEARAKRRAGAALRALLELGAREVTVRRGGAEQRIPIEQLVIGDEFVVRPGEKIAADGTVVEGASAVDAS MLTGESVPEEVQPGDQVVGATVNVDGRLVVRADRVGSDTQLAQMARMVEDAQNGKAQAQRLADRISGVFV PIVIALSVATLGFWIGSGFPVAAAFTAAVAVLIIACPCALGLATPTALMVGTGRGAQLGILIKGPEVLED TRRVDTVILDKTGTVTTGSMTLVDVFAAEGEQPDEVLRVAGAVESSSEHPIARAIAAGAQEKFGELPAVT AFTNLRGLGVSGQVDGRAVLLGRLRLLADRSHEIPSELEVAVARAESDGRTAVVVGWDGQARGVLMVADA VKPTSAEAISLLKRLGLTPIMVTGDNEAVARAVAAEVGIDEVIAGVLPQDKVDTVKRLQRDGKVVAMVGD GVNDAAALAQADLGLAMGSGTDVAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKGNLFWAFAYNVAALP LAAAGLLNPMIAGAAMAFSSVFVVSNSLRLRAFTPSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4449 | - | - | 100% (737) | heavy metal translocating P-type ATPase |
| M. vanbaalenii PYR-1 | Mvan_3670 | - | 0.0 | 68.33% (742) | heavy metal translocating P-type ATPase |
| M. vanbaalenii PYR-1 | Mvan_5853 | - | e-143 | 41.04% (770) | heavy metal translocating P-type ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0095 | ctpA | 0.0 | 52.30% (738) | cation transporter P-type ATPase A |
| M. gilvum PYR-GCK | Mflv_2244 | - | 0.0 | 87.52% (737) | heavy metal translocating P-type ATPase |
| M. tuberculosis H37Rv | Rv0092 | ctpA | 0.0 | 52.30% (738) | cation transporter P-type ATPase A |
| M. leprae Br4923 | MLBr_02000 | ctpB | 0.0 | 50.41% (736) | cation-transporting ATPase |
| M. abscessus ATCC 19977 | MAB_3984c | - | 0.0 | 56.86% (751) | putative metal transporter ATPase |
| M. marinum M | MMAR_0231 | ctpA_1 | 0.0 | 68.02% (741) | cation transporter p-type ATPase CtpA_1 |
| M. avium 104 | MAV_5246 | - | 0.0 | 65.67% (737) | copper-translocating P-type ATPase |
| M. smegmatis MC2 155 | MSMEG_5014 | - | 0.0 | 76.73% (735) | copper-translocating P-type ATPase |
| M. thermoresistible (build 8) | TH_4361 | - | 0.0 | 67.33% (750) | PUTATIVE heavy metal translocating P-type ATPase |
| M. ulcerans Agy99 | MUL_4850 | ctpA | 0.0 | 51.84% (735) | cation transporter p-type ATPase a CtpA |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4449|M.vanbaalenii_PYR-1 -------------------MNTIELSIGGMTCASCAARVEKKLNKLDGVT
Mflv_2244|M.gilvum_PYR-GCK -------------------MNTLELSIGGMTCASCAARVEKKLNKLDGVT
MSMEG_5014|M.smegmatis_MC2_155 ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT
MMAR_0231|M.marinum_M -------MPETTG--LPATLSNVELDIAGMTCASCAMRIEKKLNKLDGVS
MAV_5246|M.avium_104 MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT
TH_4361|M.thermoresistible__bu --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV
MAB_3984c|M.abscessus_ATCC_199 ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN
Mb0095|M.bovis_AF2122/97 ---MTAAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
Rv0092|M.tuberculosis_H37Rv ---MTTAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
MUL_4850|M.ulcerans_Agy99 --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR
MLBr_02000|M.leprae_Br4923 ---MTASLVEDTNNN-HESVRRIQLDVAGMLCAACASRVETKLNKIPGVR
* : ** * :** ::: **:: **
Mvan_4449|M.vanbaalenii_PYR-1 ATVNFATEKARVAFGDEVSPGQLVSAVESAGYQAELPER--------PDE
Mflv_2244|M.gilvum_PYR-GCK ATVNYATEKARVEFGDNVSTDQLVSAVESAGYQAALPEP--------PNP
MSMEG_5014|M.smegmatis_MC2_155 ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAP--------PQP
MMAR_0231|M.marinum_M ATVNYATERATVTAPAGYDPQILITEVKKAGYAAALPQHRQQPA-A-AAK
MAV_5246|M.avium_104 ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATP--------SPP
TH_4361|M.thermoresistible__bu ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGA-PAG
MAB_3984c|M.abscessus_ATCC_199 ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD
Mb0095|M.bovis_AF2122/97 AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTD--------DGR
Rv0092|M.tuberculosis_H37Rv AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTD--------DGR
MUL_4850|M.ulcerans_Agy99 ASVNFGTRTAIVEAGEDVDAAALCEVIQQAGYQAEVQPD--------DGQ
MLBr_02000|M.leprae_Br4923 ASVNFATRVATIDA-VDVAVDELRQVIEQAGYRATAHAE--------SAV
* ** . . * : * :. .** *
Mvan_4449|M.vanbaalenii_PYR-1 PA-----EPTDDPTAALKRRLLICVALSVP----VIAMAMVPVLQFTYWQ
Mflv_2244|M.gilvum_PYR-GCK PD-----VEPADPTAALRRRLIICVALSVP----VIAMAMAPPLQFTYWQ
MSMEG_5014|M.smegmatis_MC2_155 ETGGTEQDPEDRATDALRTRLLVSAVLTVP----VIAMAMVPALQFTNWQ
MMAR_0231|M.marinum_M TDT----HGVDPELASLRGRLVGAVVLAGP----VILMAMLPALQFRYWQ
MAV_5246|M.avium_104 RD--------DPELASLRRRLVTAIALAGP----VIAVAMIPALQFQHWH
TH_4361|M.thermoresistible__bu AATGAAGDDHDAEAERWRRRLTISAALSIP----VVVLSMIPALQFTHWQ
MAB_3984c|M.abscessus_ATCC_199 GHDPHDHMNHDVPDDQLKSRLIGSLILAIP----VVVISMAMPLHFSGWE
Mb0095|M.bovis_AF2122/97 SAS----DPDADHARQLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQ
Rv0092|M.tuberculosis_H37Rv SAS----DPDADHARQLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQ
MUL_4850|M.ulcerans_Agy99 GAG----DSDAEHARHLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWE
MLBr_02000|M.leprae_Br4923 EEI----DPDADYARNLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGWG
** . * * ..: :* *
Mvan_4449|M.vanbaalenii_PYR-1 WLSLTLAAPVVVWGAWPFHQAAWTNLRHGTATMDTLISIGTLAALGWSIY
Mflv_2244|M.gilvum_PYR-GCK WLSLTLAAPVVVWGAWPFHRATWANLRHGTATMDTLISVGTLAAFGWSIY
MSMEG_5014|M.smegmatis_MC2_155 WLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLY
MMAR_0231|M.marinum_M WASLALAAPVIVWAGRPFHQAAWVNLKHGTATMDTLISVGTLAAFLWSLY
MAV_5246|M.avium_104 WAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLY
TH_4361|M.thermoresistible__bu WLALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLW
MAB_3984c|M.abscessus_ATCC_199 ILVAALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLW
Mb0095|M.bovis_AF2122/97 WVLSALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLY
Rv0092|M.tuberculosis_H37Rv WVLSALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLY
MUL_4850|M.ulcerans_Agy99 WVLTALALPVVTWAAWPFHRIALRNARHHGASMETLISVGITAATIWSLY
MLBr_02000|M.leprae_Br4923 YLLTALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLS
:*: *:: * . *** : * :: ::*:**:* * ** **:
Mvan_4449|M.vanbaalenii_PYR-1 ALFWGTAGIPGMTHPFELTIARTDGTS------NIYLEAAAGVTTFILAG
Mflv_2244|M.gilvum_PYR-GCK ALFWGTAGVPGMTHPFELTIARTDGSG------NIYLEAAAGVTTFILAG
MSMEG_5014|M.smegmatis_MC2_155 ALFWGTAGVPGMTHPFSLVGSRTDGAG------NIYLEVAAGVTTFILAG
MMAR_0231|M.marinum_M ALFLGTAGEPGMRHPFELTITPGDGAS------NIYLEVAAGVIAFVLAG
MAV_5246|M.avium_104 ALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAG
TH_4361|M.thermoresistible__bu ALFFTAAGMPGMTMTFTLLPADTGEPH-------IYLEVAAAVTTFIIAG
MAB_3984c|M.abscessus_ATCC_199 VLFANAGHTHGDVH--------------------VYFEVVAAVTVFLLAG
Mb0095|M.bovis_AF2122/97 TVFGNHSPIERSGIWQALLGSDA-----------IYFEVAAGVTVFVLVG
Rv0092|M.tuberculosis_H37Rv TVFGNHSPIERSGIWQALLGSDA-----------IYFEVAAGVTVFVLVG
MUL_4850|M.ulcerans_Agy99 TVFGSHQLADRKGIWQALLGSDA-----------IYFEVAAGVTVFVLAG
MLBr_02000|M.leprae_Br4923 TIFVDKEPRQTHGIWQAILHSDS-----------IYFEVAAGVTVFVLAG
.:. :*:*..*.* *::.*
Mvan_4449|M.vanbaalenii_PYR-1 RYFEARAKRRAGAALRALLELGAREVTVR-RGGAEQRIPIEQLVIGDEFV
Mflv_2244|M.gilvum_PYR-GCK RYFEARAKRRAGAALRALLELGVRDVTVR-RGAAEHRIPIDQLRVDDEFV
MSMEG_5014|M.smegmatis_MC2_155 RYFEAKSKRRASAALRALMELGAKDVAIL-RNGAEQRIPIDQLGVGDEFV
MMAR_0231|M.marinum_M RYFEKRSKRRAGAALQALLELGAKDVAVL-RNGAEIRVPVQELTVDDEFV
MAV_5246|M.avium_104 RYFERRSKRTAGAALRALLALGAKDVAVL-RAGAETRIPIERLAVGDEFV
TH_4361|M.thermoresistible__bu RYFEARAKRQSGAALRALLDMGANDVAVL-RDGAEKRVPIGELHVGDVFV
MAB_3984c|M.abscessus_ATCC_199 RFAESRAKRSAGSALRALLSLGAKDVAVL-RGGHETRIPVDQLAVGDEFV
Mb0095|M.bovis_AF2122/97 RYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFV
Rv0092|M.tuberculosis_H37Rv RYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFV
MUL_4850|M.ulcerans_Agy99 RYFEARAKSKAGAALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFV
MLBr_02000|M.leprae_Br4923 RFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFL
*: * ::* :.:**:** ...:* : . * :* .* : *:
Mvan_4449|M.vanbaalenii_PYR-1 VRPGEKIAADGTVVEGASAVDASMLTGESVPEEVQPGDQVVGATVNVDGR
Mflv_2244|M.gilvum_PYR-GCK VRPGEKVAADGIIVEGASAVDASMLTGESVPLEVKPGDRVVGATVNVDGR
MSMEG_5014|M.smegmatis_MC2_155 VRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGR
MMAR_0231|M.marinum_M VRPGEKIATDGTVVAGSSAVDASMLTGESVPVEVGPGDTVTGATTNAGGR
MAV_5246|M.avium_104 VRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGR
TH_4361|M.thermoresistible__bu VRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGH
MAB_3984c|M.abscessus_ATCC_199 VRPGERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGR
Mb0095|M.bovis_AF2122/97 VRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGR
Rv0092|M.tuberculosis_H37Rv VRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGR
MUL_4850|M.ulcerans_Agy99 VRPGQTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGR
MLBr_02000|M.leprae_Br4923 VRPGETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGR
****: :::** : * :::* : :***: * .. .. * *. . *:
Mvan_4449|M.vanbaalenii_PYR-1 LVVRADRVGSDTQLAQMARMVEDAQNGKAQAQRLADRISGVFVPIVIALS
Mflv_2244|M.gilvum_PYR-GCK LVVRAERVGADTQLAQMARLVEDAQNGKAQAQRLADRISGVFVPVVLGLA
MSMEG_5014|M.smegmatis_MC2_155 LVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALA
MMAR_0231|M.marinum_M LVVRATRVGEHTQLAQMAKLVEAAQSGKADVQRLADRVSGVFVPIVIAIA
MAV_5246|M.avium_104 LVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLA
TH_4361|M.thermoresistible__bu LQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALS
MAB_3984c|M.abscessus_ATCC_199 IVVRANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAIS
Mb0095|M.bovis_AF2122/97 LIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIA
Rv0092|M.tuberculosis_H37Rv LIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIA
MUL_4850|M.ulcerans_Agy99 LIVEAAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIA
MLBr_02000|M.leprae_Br4923 LVIEATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMVFVIA
: :.* :* .*::* *.::* ** ** .*:****::.**** *: ::
Mvan_4449|M.vanbaalenii_PYR-1 VATLGFWIG-SGFPVAAAFTAAVAVLIIACPCALGLATPTALMVGTGRGA
Mflv_2244|M.gilvum_PYR-GCK VATLGFWIG-SGYPVAAAFTAAVAVLIIACPCALGLATPMALMVGTGRGA
MSMEG_5014|M.smegmatis_MC2_155 VATLGFWLG-TGGSVAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
MMAR_0231|M.marinum_M VTTLGVWLG-AGYPVSAALTAAVAVLIIACPCALGLATPTALLVGTGRAA
MAV_5246|M.avium_104 VATLAGWLA-AGGTLATALTAAVAVLIIACPCALGLATPTALLVGTGRAA
TH_4361|M.thermoresistible__bu ALTLAGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
MAB_3984c|M.abscessus_ATCC_199 ALTFVAWAA-LGNSLASAFTAAVAVLIIACPCALGLATPTAILVGTGRGA
Mb0095|M.bovis_AF2122/97 ALTAAGWLI-AGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASGRGA
Rv0092|M.tuberculosis_H37Rv ALTAAGWLI-AGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASGRGA
MUL_4850|M.ulcerans_Agy99 ALTAAGWLL-AGGSPDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGA
MLBr_02000|M.leprae_Br4923 GLAGASWLL-AGASPDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGA
: * . *.:..:.**:*****:****** *::*.:**.*
Mvan_4449|M.vanbaalenii_PYR-1 QLGILIKGPEVLEDTRRVDTVILDKTGTVTTGSMTLVDVFAAEGE---QP
Mflv_2244|M.gilvum_PYR-GCK QLGILIKGPEVLESTRRVDTVIVDKTGTVTTGDMTLVDVFAADGE---QP
MSMEG_5014|M.smegmatis_MC2_155 QLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE---DR
MMAR_0231|M.marinum_M ALGVLIKGPEMLESTRRVDTIVLDKTGTVTTGKMTLLEVITVPDT---DR
MAV_5246|M.avium_104 QLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT---DR
TH_4361|M.thermoresistible__bu QLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL---SE
MAB_3984c|M.abscessus_ATCC_199 QLGVLIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGVADA
Mb0095|M.bovis_AF2122/97 QLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EA
Rv0092|M.tuberculosis_H37Rv QLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EA
MUL_4850|M.ulcerans_Agy99 QLGIFLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DA
MLBr_02000|M.leprae_Br4923 QLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGGW---CS
**:::** . ** . :**::.*****:* * : : * .
Mvan_4449|M.vanbaalenii_PYR-1 DEVLRVAGAVESSSEHPIARAIAAGAQEKFGELPAVTAFTNLRGLGVSGQ
Mflv_2244|M.gilvum_PYR-GCK DEVLRMAGAVESPSEHPIAAAIAGGARDKLGDLPAVDGFANLRGLGVEGD
MSMEG_5014|M.smegmatis_MC2_155 DDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQGT
MMAR_0231|M.marinum_M ATALRYAGGLEAASEHPIAAAIVKSARAELGALPEPADFANTEGQGVRGI
MAV_5246|M.avium_104 ATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGR
TH_4361|M.thermoresistible__bu TELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGR
MAB_3984c|M.abscessus_ATCC_199 DEILRIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSGV
Mb0095|M.bovis_AF2122/97 DQVLALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGT
Rv0092|M.tuberculosis_H37Rv DQVLALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGT
MUL_4850|M.ulcerans_Agy99 DEVLAIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGT
MLBr_02000|M.leprae_Br4923 GEVLALASAVEAASEHSVATAIVAAYADPR----PVADFVAFAGCGVSGV
* *. :* .***.:* *:. * * ** *
Mvan_4449|M.vanbaalenii_PYR-1 VDGRAVLLGRLRLLADRSHEIPSELEVAVARAESDGRTAVVVGWDGQARG
Mflv_2244|M.gilvum_PYR-GCK VEGRRLTLGRLRLLSDRSFEIPDDLASAVARAEAGGSTAVTVGWDGRARG
MSMEG_5014|M.smegmatis_MC2_155 VEGRAVVVGRPRLFGDPEKSLPRKLADAMEAAQAQGRTAVVVGWDGTARG
MMAR_0231|M.marinum_M IDGHAVIVGRASLLADWAQHLDPDLAAAKDRAESQGKTAVAVGWDGRARA
MAV_5246|M.avium_104 VDGHAVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAVGWDGRARG
TH_4361|M.thermoresistible__bu VDGHDVRVGRLAWLG---LSAGDRLRNAAAQAEAAGHTPVWVAVDGRIAG
MAB_3984c|M.abscessus_ATCC_199 VDGQEVSI----------------------EAIEGQNTTAAVSWGGLRRG
Mb0095|M.bovis_AF2122/97 VSGRAVRVGKPSWIG--SSSCHPNMRAARRHAESLGETAVFVEVDGEPCG
Rv0092|M.tuberculosis_H37Rv VSGRAVRVGKPSWIG--SSSCHPNMRAARRHAESLGETAVFVEVDGEPCG
MUL_4850|M.ulcerans_Agy99 VSGRSVRVGKPSWIG--SSSSDTALRAALRNAESLGETAVFVEIDGGPCG
MLBr_02000|M.leprae_Br4923 VAEHHVKIGKPSWVTR-NAPCDVVLESARREGESRGETVVFVSVDGVACG
: : : : . * . * .* .
Mvan_4449|M.vanbaalenii_PYR-1 VLMVADAVKPTSAEAISLLKRLGLTPIMVTGDNEAVARAVAAEVGID--E
Mflv_2244|M.gilvum_PYR-GCK VLMVADAVKPTSAEAISLLKRAGLTPIMVTGDNEAVARTVAAQVGID--E
MSMEG_5014|M.smegmatis_MC2_155 VLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID--D
MMAR_0231|M.marinum_M ILVIADTVKPTSAAAIREFKRLGLTPVLLTGDNPTVARHIADEVGID--E
MAV_5246|M.avium_104 ILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG--E
TH_4361|M.thermoresistible__bu VIVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID--D
MAB_3984c|M.abscessus_ATCC_199 EIEVADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAAGD
Mb0095|M.bovis_AF2122/97 VIAVADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--E
Rv0092|M.tuberculosis_H37Rv VIAVADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--E
MUL_4850|M.ulcerans_Agy99 VIAVADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--E
MLBr_02000|M.leprae_Br4923 AVAIADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGID--T
: ::*:** : *: : * .:::**** * * .:**
Mvan_4449|M.vanbaalenii_PYR-1 VIAGVLPQDKVDTVKRLQRDGKVVAMVGDGVNDAAALAQADLGLAMGSGT
Mflv_2244|M.gilvum_PYR-GCK VVAGVLPQDKVDTVTRLQRDGRVVAMVGDGVNDAAALAQADLGMAMGSGT
MSMEG_5014|M.smegmatis_MC2_155 VYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTGT
MMAR_0231|M.marinum_M VIADVLPAGKVAAVRRLQSEGKIVAMVGDGVNDAAALATADLGLAMGTGA
MAV_5246|M.avium_104 VISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTGT
TH_4361|M.thermoresistible__bu VIAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTGT
MAB_3984c|M.abscessus_ATCC_199 VIAGVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGTGT
Mb0095|M.bovis_AF2122/97 VIADILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGT
Rv0092|M.tuberculosis_H37Rv VIADILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGT
MUL_4850|M.ulcerans_Agy99 VIANILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRGT
MLBr_02000|M.leprae_Br4923 VIADMLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGLAMGRGT
* : * *. : :*: *: ***:***:**..*** **:*:::* *:
Mvan_4449|M.vanbaalenii_PYR-1 DVAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKGNLFWAFAYNVAALPL
Mflv_2244|M.gilvum_PYR-GCK DVAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKSNLFWAFAYNVAALPL
MSMEG_5014|M.smegmatis_MC2_155 DVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAALPL
MMAR_0231|M.marinum_M DVAIEAADLTLVRGDLRAAADAIRLSRRTLNTIKTNLFWAFGYNVAALPL
MAV_5246|M.avium_104 DVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPL
TH_4361|M.thermoresistible__bu DVAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALPL
MAB_3984c|M.abscessus_ATCC_199 DAAIEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAIPL
Mb0095|M.bovis_AF2122/97 DVAIGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPV
Rv0092|M.tuberculosis_H37Rv DVAIGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPV
MUL_4850|M.ulcerans_Agy99 DVAIGAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIPI
MLBr_02000|M.leprae_Br4923 DVAIGAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAIPI
*.** *.*: :* . * .. *: *. *: *:: *: ***.** **:*:
Mvan_4449|M.vanbaalenii_PYR-1 AAAGLLNPMIAGAAMAFSSVFVVSNSLRLRAFTPSR--------------
Mflv_2244|M.gilvum_PYR-GCK AAAGLLNPMIAGAAMAFSSVFVVTNSLRLRAFTPSR--------------
MSMEG_5014|M.smegmatis_MC2_155 AAAGLLNPMLAGAAMAFSSVFVVSNSLRLKRFR-----------------
MMAR_0231|M.marinum_M AAFGLLNPMLAGAAMAFSSVFVVGNSLRLRSFTSVITDAPPATGSPTRWD
MAV_5246|M.avium_104 AALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA-----------
TH_4361|M.thermoresistible__bu AAAGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR--------------
MAB_3984c|M.abscessus_ATCC_199 AALGLLNPMIAGAAMAMSSVFVVLNSLRLRTFR-----------------
Mb0095|M.bovis_AF2122/97 AAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAP
Rv0092|M.tuberculosis_H37Rv AAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAP
MUL_4850|M.ulcerans_Agy99 AAAGVLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQTTTSTTEP
MLBr_02000|M.leprae_Br4923 ASSGLLNPLIAGAAMAFSSFFVVSNSLRLSNFG-------------LSQT
*: *:***::******:**.:** ***:* *
Mvan_4449|M.vanbaalenii_PYR-1 ---------------------
Mflv_2244|M.gilvum_PYR-GCK ---------------------
MSMEG_5014|M.smegmatis_MC2_155 ---------------------
MMAR_0231|M.marinum_M ATPESPAELSTLPGEPSGCPR
MAV_5246|M.avium_104 ---------------------
TH_4361|M.thermoresistible__bu ---------------------
MAB_3984c|M.abscessus_ATCC_199 ---------------------
Mb0095|M.bovis_AF2122/97 SSA------------------
Rv0092|M.tuberculosis_H37Rv SSA------------------
MUL_4850|M.ulcerans_Agy99 GATE-----------------
MLBr_02000|M.leprae_Br4923 SD-------------------