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M. gilvum PYR-GCK Mflv_2244 (-)

annotation: heavy metal translocating P-type ATPase
coordinates: 2326309 - 2328522
length: 737

NTLELSIGGMTCASCAARVEKKLNKLDGVTATVNYATEKARVEFGDNVSTDQLVSAVESAGYQAALPEPP
NPPDVEPADPTAALRRRLIICVALSVPVIAMAMAPPLQFTYWQWLSLTLAAPVVVWGAWPFHRATWANLR
HGTATMDTLISVGTLAAFGWSIYALFWGTAGVPGMTHPFELTIARTDGSGNIYLEAAAGVTTFILAGRYF
EARAKRRAGAALRALLELGVRDVTVRRGAAEHRIPIDQLRVDDEFVVRPGEKVAADGIIVEGASAVDASM
LTGESVPLEVKPGDRVVGATVNVDGRLVVRAERVGADTQLAQMARLVEDAQNGKAQAQRLADRISGVFVP
VVLGLAVATLGFWIGSGYPVAAAFTAAVAVLIIACPCALGLATPMALMVGTGRGAQLGILIKGPEVLEST
RRVDTVIVDKTGTVTTGDMTLVDVFAADGEQPDEVLRMAGAVESPSEHPIAAAIAGGARDKLGDLPAVDG
FANLRGLGVEGDVEGRRLTLGRLRLLSDRSFEIPDDLASAVARAEAGGSTAVTVGWDGRARGVLMVADAV
KPTSAEAISLLKRAGLTPIMVTGDNEAVARTVAAQVGIDEVVAGVLPQDKVDTVTRLQRDGRVVAMVGDG
VNDAAALAQADLGMAMGSGTDVAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKSNLFWAFAYNVAALPL
AAAGLLNPMIAGAAMAFSSVFVVTNSLRLRAFTPSR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2244--100% (737)heavy metal translocating P-type ATPase
M. gilvum PYR-GCKMflv_2849-0.070.15% (737) heavy metal translocating P-type ATPase
M. gilvum PYR-GCKMflv_0912-0.069.41% (742) heavy metal translocating P-type ATPase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0095ctpA0.051.15% (741) cation transporter P-type ATPase A
M. tuberculosis H37RvRv0092ctpA0.051.15% (741) cation transporter P-type ATPase A
M. leprae Br4923MLBr_02000ctpB0.048.99% (739) cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-0.055.93% (751) putative metal transporter ATPase
M. marinum MMMAR_0231ctpA_10.067.48% (741) cation transporter p-type ATPase CtpA_1
M. avium 104MAV_5246-0.064.86% (737) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-0.075.37% (735) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-0.065.73% (750) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_4850ctpA0.050.20% (739) cation transporter p-type ATPase a CtpA
M. vanbaalenii PYR-1Mvan_4449-0.087.52% (737) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2244|M.gilvum_PYR-GCK          -------------------MNTLELSIGGMTCASCAARVEKKLNKLDGVT
Mvan_4449|M.vanbaalenii_PYR-1       -------------------MNTIELSIGGMTCASCAARVEKKLNKLDGVT
MSMEG_5014|M.smegmatis_MC2_155      ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT
MMAR_0231|M.marinum_M               -------MPETTG--LPATLSNVELDIAGMTCASCAMRIEKKLNKLDGVS
MAV_5246|M.avium_104                MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT
TH_4361|M.thermoresistible__bu      --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV
MAB_3984c|M.abscessus_ATCC_199      ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN
Mb0095|M.bovis_AF2122/97            ---MTAAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
Rv0092|M.tuberculosis_H37Rv         ---MTTAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
MUL_4850|M.ulcerans_Agy99           --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR
MLBr_02000|M.leprae_Br4923          ---MTASLVEDTNNN-HESVRRIQLDVAGMLCAACASRVETKLNKIPGVR
                                                            * : ** * :** :::  **:: ** 

Mflv_2244|M.gilvum_PYR-GCK          ATVNYATEKARVEFGDNVSTDQLVSAVESAGYQAALPEP--------PNP
Mvan_4449|M.vanbaalenii_PYR-1       ATVNFATEKARVAFGDEVSPGQLVSAVESAGYQAELPER--------PDE
MSMEG_5014|M.smegmatis_MC2_155      ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAP--------PQP
MMAR_0231|M.marinum_M               ATVNYATERATVTAPAGYDPQILITEVKKAGYAAALPQHRQQPA-A-AAK
MAV_5246|M.avium_104                ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATP--------SPP
TH_4361|M.thermoresistible__bu      ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGA-PAG
MAB_3984c|M.abscessus_ATCC_199      ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD
Mb0095|M.bovis_AF2122/97            AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTD--------DGR
Rv0092|M.tuberculosis_H37Rv         AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTD--------DGR
MUL_4850|M.ulcerans_Agy99           ASVNFGTRTAIVEAGEDVDAAALCEVIQQAGYQAEVQPD--------DGQ
MLBr_02000|M.leprae_Br4923          ASVNFATRVATIDA-VDVAVDELRQVIEQAGYRATAHAE--------SAV
                                    * ** . . * :          *   :. .** *                

Mflv_2244|M.gilvum_PYR-GCK          PD-----VEPADPTAALRRRLIICVALSVP----VIAMAMAPPLQFTYWQ
Mvan_4449|M.vanbaalenii_PYR-1       PA-----EPTDDPTAALKRRLLICVALSVP----VIAMAMVPVLQFTYWQ
MSMEG_5014|M.smegmatis_MC2_155      ETGGTEQDPEDRATDALRTRLLVSAVLTVP----VIAMAMVPALQFTNWQ
MMAR_0231|M.marinum_M               TDT----HGVDPELASLRGRLVGAVVLAGP----VILMAMLPALQFRYWQ
MAV_5246|M.avium_104                RD--------DPELASLRRRLVTAIALAGP----VIAVAMIPALQFQHWH
TH_4361|M.thermoresistible__bu      AATGAAGDDHDAEAERWRRRLTISAALSIP----VVVLSMIPALQFTHWQ
MAB_3984c|M.abscessus_ATCC_199      GHDPHDHMNHDVPDDQLKSRLIGSLILAIP----VVVISMAMPLHFSGWE
Mb0095|M.bovis_AF2122/97            SAS----DPDADHARQLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQ
Rv0092|M.tuberculosis_H37Rv         SAS----DPDADHARQLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQ
MUL_4850|M.ulcerans_Agy99           GAG----DSDAEHARHLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWE
MLBr_02000|M.leprae_Br4923          EEI----DPDADYARNLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGWG
                                                       **  .  *  *       ..:    :*  * 

Mflv_2244|M.gilvum_PYR-GCK          WLSLTLAAPVVVWGAWPFHRATWANLRHGTATMDTLISVGTLAAFGWSIY
Mvan_4449|M.vanbaalenii_PYR-1       WLSLTLAAPVVVWGAWPFHQAAWTNLRHGTATMDTLISIGTLAALGWSIY
MSMEG_5014|M.smegmatis_MC2_155      WLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLY
MMAR_0231|M.marinum_M               WASLALAAPVIVWAGRPFHQAAWVNLKHGTATMDTLISVGTLAAFLWSLY
MAV_5246|M.avium_104                WAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLY
TH_4361|M.thermoresistible__bu      WLALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLW
MAB_3984c|M.abscessus_ATCC_199      ILVAALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLW
Mb0095|M.bovis_AF2122/97            WVLSALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLY
Rv0092|M.tuberculosis_H37Rv         WVLSALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLY
MUL_4850|M.ulcerans_Agy99           WVLTALALPVVTWAAWPFHRIALRNARHHGASMETLISVGITAATIWSLY
MLBr_02000|M.leprae_Br4923          YLLTALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLS
                                        :*: *:: * . ***  :  * ::  ::*:**:* *  **  **: 

Mflv_2244|M.gilvum_PYR-GCK          ALFWGTAGVPGMTHPFELTIARTDGSG------NIYLEAAAGVTTFILAG
Mvan_4449|M.vanbaalenii_PYR-1       ALFWGTAGIPGMTHPFELTIARTDGTS------NIYLEAAAGVTTFILAG
MSMEG_5014|M.smegmatis_MC2_155      ALFWGTAGVPGMTHPFSLVGSRTDGAG------NIYLEVAAGVTTFILAG
MMAR_0231|M.marinum_M               ALFLGTAGEPGMRHPFELTITPGDGAS------NIYLEVAAGVIAFVLAG
MAV_5246|M.avium_104                ALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAG
TH_4361|M.thermoresistible__bu      ALFFTAAGMPGMTMTFTLLPADTGEPH-------IYLEVAAAVTTFIIAG
MAB_3984c|M.abscessus_ATCC_199      VLFANAGHTHGDVH--------------------VYFEVVAAVTVFLLAG
Mb0095|M.bovis_AF2122/97            TVFGNHSPIERSGIWQALLGSDA-----------IYFEVAAGVTVFVLVG
Rv0092|M.tuberculosis_H37Rv         TVFGNHSPIERSGIWQALLGSDA-----------IYFEVAAGVTVFVLVG
MUL_4850|M.ulcerans_Agy99           TVFGSHQLADRKGIWQALLGSDA-----------IYFEVAAGVTVFVLAG
MLBr_02000|M.leprae_Br4923          TIFVDKEPRQTHGIWQAILHSDS-----------IYFEVAAGVTVFVLAG
                                    .:.                               :*:*..*.*  *::.*

Mflv_2244|M.gilvum_PYR-GCK          RYFEARAKRRAGAALRALLELGVRDVTVR-RGAAEHRIPIDQLRVDDEFV
Mvan_4449|M.vanbaalenii_PYR-1       RYFEARAKRRAGAALRALLELGAREVTVR-RGGAEQRIPIEQLVIGDEFV
MSMEG_5014|M.smegmatis_MC2_155      RYFEAKSKRRASAALRALMELGAKDVAIL-RNGAEQRIPIDQLGVGDEFV
MMAR_0231|M.marinum_M               RYFEKRSKRRAGAALQALLELGAKDVAVL-RNGAEIRVPVQELTVDDEFV
MAV_5246|M.avium_104                RYFERRSKRTAGAALRALLALGAKDVAVL-RAGAETRIPIERLAVGDEFV
TH_4361|M.thermoresistible__bu      RYFEARAKRQSGAALRALLDMGANDVAVL-RDGAEKRVPIGELHVGDVFV
MAB_3984c|M.abscessus_ATCC_199      RFAESRAKRSAGSALRALLSLGAKDVAVL-RGGHETRIPVDQLAVGDEFV
Mb0095|M.bovis_AF2122/97            RYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFV
Rv0092|M.tuberculosis_H37Rv         RYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFV
MUL_4850|M.ulcerans_Agy99           RYFEARAKSKAGAALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFV
MLBr_02000|M.leprae_Br4923          RFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFL
                                    *: * ::*  :.:**:**   ...:* :    . *  :*  .*   : *:

Mflv_2244|M.gilvum_PYR-GCK          VRPGEKVAADGIIVEGASAVDASMLTGESVPLEVKPGDRVVGATVNVDGR
Mvan_4449|M.vanbaalenii_PYR-1       VRPGEKIAADGTVVEGASAVDASMLTGESVPEEVQPGDQVVGATVNVDGR
MSMEG_5014|M.smegmatis_MC2_155      VRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGR
MMAR_0231|M.marinum_M               VRPGEKIATDGTVVAGSSAVDASMLTGESVPVEVGPGDTVTGATTNAGGR
MAV_5246|M.avium_104                VRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGR
TH_4361|M.thermoresistible__bu      VRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGH
MAB_3984c|M.abscessus_ATCC_199      VRPGERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGR
Mb0095|M.bovis_AF2122/97            VRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGR
Rv0092|M.tuberculosis_H37Rv         VRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGR
MUL_4850|M.ulcerans_Agy99           VRPGQTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGR
MLBr_02000|M.leprae_Br4923          VRPGETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGR
                                    ****: :::**  : * :::* : :***: * ..  .. * *. .   *:

Mflv_2244|M.gilvum_PYR-GCK          LVVRAERVGADTQLAQMARLVEDAQNGKAQAQRLADRISGVFVPVVLGLA
Mvan_4449|M.vanbaalenii_PYR-1       LVVRADRVGSDTQLAQMARMVEDAQNGKAQAQRLADRISGVFVPIVIALS
MSMEG_5014|M.smegmatis_MC2_155      LVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALA
MMAR_0231|M.marinum_M               LVVRATRVGEHTQLAQMAKLVEAAQSGKADVQRLADRVSGVFVPIVIAIA
MAV_5246|M.avium_104                LVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLA
TH_4361|M.thermoresistible__bu      LQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALS
MAB_3984c|M.abscessus_ATCC_199      IVVRANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAIS
Mb0095|M.bovis_AF2122/97            LIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIA
Rv0092|M.tuberculosis_H37Rv         LIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIA
MUL_4850|M.ulcerans_Agy99           LIVEAAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIA
MLBr_02000|M.leprae_Br4923          LVIEATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMVFVIA
                                    : :.*  :* .*::* *.::*  **  ** .*:****::.**** *: ::

Mflv_2244|M.gilvum_PYR-GCK          VATLGFWIG-SGYPVAAAFTAAVAVLIIACPCALGLATPMALMVGTGRGA
Mvan_4449|M.vanbaalenii_PYR-1       VATLGFWIG-SGFPVAAAFTAAVAVLIIACPCALGLATPTALMVGTGRGA
MSMEG_5014|M.smegmatis_MC2_155      VATLGFWLG-TGGSVAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
MMAR_0231|M.marinum_M               VTTLGVWLG-AGYPVSAALTAAVAVLIIACPCALGLATPTALLVGTGRAA
MAV_5246|M.avium_104                VATLAGWLA-AGGTLATALTAAVAVLIIACPCALGLATPTALLVGTGRAA
TH_4361|M.thermoresistible__bu      ALTLAGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
MAB_3984c|M.abscessus_ATCC_199      ALTFVAWAA-LGNSLASAFTAAVAVLIIACPCALGLATPTAILVGTGRGA
Mb0095|M.bovis_AF2122/97            ALTAAGWLI-AGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASGRGA
Rv0092|M.tuberculosis_H37Rv         ALTAAGWLI-AGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASGRGA
MUL_4850|M.ulcerans_Agy99           ALTAAGWLL-AGGSPDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGA
MLBr_02000|M.leprae_Br4923          GLAGASWLL-AGASPDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGA
                                      :   *    .     *.:..:.**:*****:****** *::*.:**.*

Mflv_2244|M.gilvum_PYR-GCK          QLGILIKGPEVLESTRRVDTVIVDKTGTVTTGDMTLVDVFAADGE---QP
Mvan_4449|M.vanbaalenii_PYR-1       QLGILIKGPEVLEDTRRVDTVILDKTGTVTTGSMTLVDVFAAEGE---QP
MSMEG_5014|M.smegmatis_MC2_155      QLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE---DR
MMAR_0231|M.marinum_M               ALGVLIKGPEMLESTRRVDTIVLDKTGTVTTGKMTLLEVITVPDT---DR
MAV_5246|M.avium_104                QLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT---DR
TH_4361|M.thermoresistible__bu      QLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL---SE
MAB_3984c|M.abscessus_ATCC_199      QLGVLIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGVADA
Mb0095|M.bovis_AF2122/97            QLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EA
Rv0092|M.tuberculosis_H37Rv         QLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EA
MUL_4850|M.ulcerans_Agy99           QLGIFLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DA
MLBr_02000|M.leprae_Br4923          QLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGGW---CS
                                     **:::** . **  . :**::.*****:* * : :  *    .      

Mflv_2244|M.gilvum_PYR-GCK          DEVLRMAGAVESPSEHPIAAAIAGGARDKLGDLPAVDGFANLRGLGVEGD
Mvan_4449|M.vanbaalenii_PYR-1       DEVLRVAGAVESSSEHPIARAIAAGAQEKFGELPAVTAFTNLRGLGVSGQ
MSMEG_5014|M.smegmatis_MC2_155      DDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQGT
MMAR_0231|M.marinum_M               ATALRYAGGLEAASEHPIAAAIVKSARAELGALPEPADFANTEGQGVRGI
MAV_5246|M.avium_104                ATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGR
TH_4361|M.thermoresistible__bu      TELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGR
MAB_3984c|M.abscessus_ATCC_199      DEILRIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSGV
Mb0095|M.bovis_AF2122/97            DQVLALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGT
Rv0092|M.tuberculosis_H37Rv         DQVLALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGT
MUL_4850|M.ulcerans_Agy99           DEVLAIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGT
MLBr_02000|M.leprae_Br4923          GEVLALASAVEAASEHSVATAIVAAYADPR----PVADFVAFAGCGVSGV
                                       *  *. :* .***.:* *:.               *    * ** * 

Mflv_2244|M.gilvum_PYR-GCK          VEGRRLTLGRLRLLSDRSFEIPDDLASAVARAEAGGSTAVTVGWDGRARG
Mvan_4449|M.vanbaalenii_PYR-1       VDGRAVLLGRLRLLADRSHEIPSELEVAVARAESDGRTAVVVGWDGQARG
MSMEG_5014|M.smegmatis_MC2_155      VEGRAVVVGRPRLFGDPEKSLPRKLADAMEAAQAQGRTAVVVGWDGTARG
MMAR_0231|M.marinum_M               IDGHAVIVGRASLLADWAQHLDPDLAAAKDRAESQGKTAVAVGWDGRARA
MAV_5246|M.avium_104                VDGHAVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAVGWDGRARG
TH_4361|M.thermoresistible__bu      VDGHDVRVGRLAWLG---LSAGDRLRNAAAQAEAAGHTPVWVAVDGRIAG
MAB_3984c|M.abscessus_ATCC_199      VDGQEVSI----------------------EAIEGQNTTAAVSWGGLRRG
Mb0095|M.bovis_AF2122/97            VSGRAVRVGKPSWIG--SSSCHPNMRAARRHAESLGETAVFVEVDGEPCG
Rv0092|M.tuberculosis_H37Rv         VSGRAVRVGKPSWIG--SSSCHPNMRAARRHAESLGETAVFVEVDGEPCG
MUL_4850|M.ulcerans_Agy99           VSGRSVRVGKPSWIG--SSSSDTALRAALRNAESLGETAVFVEIDGGPCG
MLBr_02000|M.leprae_Br4923          VAEHHVKIGKPSWVTR-NAPCDVVLESARREGESRGETVVFVSVDGVACG
                                    :  : : :                       .     * . *  .*   .

Mflv_2244|M.gilvum_PYR-GCK          VLMVADAVKPTSAEAISLLKRAGLTPIMVTGDNEAVARTVAAQVGID--E
Mvan_4449|M.vanbaalenii_PYR-1       VLMVADAVKPTSAEAISLLKRLGLTPIMVTGDNEAVARAVAAEVGID--E
MSMEG_5014|M.smegmatis_MC2_155      VLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID--D
MMAR_0231|M.marinum_M               ILVIADTVKPTSAAAIREFKRLGLTPVLLTGDNPTVARHIADEVGID--E
MAV_5246|M.avium_104                ILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG--E
TH_4361|M.thermoresistible__bu      VIVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID--D
MAB_3984c|M.abscessus_ATCC_199      EIEVADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAAGD
Mb0095|M.bovis_AF2122/97            VIAVADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--E
Rv0092|M.tuberculosis_H37Rv         VIAVADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--E
MUL_4850|M.ulcerans_Agy99           VIAVADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--E
MLBr_02000|M.leprae_Br4923          AVAIADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGID--T
                                     : ::*:**  :  *:  :   *  .:::****   *   * .:**    

Mflv_2244|M.gilvum_PYR-GCK          VVAGVLPQDKVDTVTRLQRDGRVVAMVGDGVNDAAALAQADLGMAMGSGT
Mvan_4449|M.vanbaalenii_PYR-1       VIAGVLPQDKVDTVKRLQRDGKVVAMVGDGVNDAAALAQADLGLAMGSGT
MSMEG_5014|M.smegmatis_MC2_155      VYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTGT
MMAR_0231|M.marinum_M               VIADVLPAGKVAAVRRLQSEGKIVAMVGDGVNDAAALATADLGLAMGTGA
MAV_5246|M.avium_104                VISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTGT
TH_4361|M.thermoresistible__bu      VIAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTGT
MAB_3984c|M.abscessus_ATCC_199      VIAGVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGTGT
Mb0095|M.bovis_AF2122/97            VIADILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGT
Rv0092|M.tuberculosis_H37Rv         VIADILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGT
MUL_4850|M.ulcerans_Agy99           VIANILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRGT
MLBr_02000|M.leprae_Br4923          VIADMLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGLAMGRGT
                                    * :   *  *.  : :*:  *: ***:***:**..*** **:*:::* *:

Mflv_2244|M.gilvum_PYR-GCK          DVAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKSNLFWAFAYNVAALPL
Mvan_4449|M.vanbaalenii_PYR-1       DVAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKGNLFWAFAYNVAALPL
MSMEG_5014|M.smegmatis_MC2_155      DVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAALPL
MMAR_0231|M.marinum_M               DVAIEAADLTLVRGDLRAAADAIRLSRRTLNTIKTNLFWAFGYNVAALPL
MAV_5246|M.avium_104                DVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPL
TH_4361|M.thermoresistible__bu      DVAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALPL
MAB_3984c|M.abscessus_ATCC_199      DAAIEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAIPL
Mb0095|M.bovis_AF2122/97            DVAIGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPV
Rv0092|M.tuberculosis_H37Rv         DVAIGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPV
MUL_4850|M.ulcerans_Agy99           DVAIGAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIPI
MLBr_02000|M.leprae_Br4923          DVAIGAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAIPI
                                    *.** *.*: :* . * ..  *: *.  *: *:: *: ***.** **:*:

Mflv_2244|M.gilvum_PYR-GCK          AAAGLLNPMIAGAAMAFSSVFVVTNSLRLRAFTPSR--------------
Mvan_4449|M.vanbaalenii_PYR-1       AAAGLLNPMIAGAAMAFSSVFVVSNSLRLRAFTPSR--------------
MSMEG_5014|M.smegmatis_MC2_155      AAAGLLNPMLAGAAMAFSSVFVVSNSLRLKRFR-----------------
MMAR_0231|M.marinum_M               AAFGLLNPMLAGAAMAFSSVFVVGNSLRLRSFTSVITDAPPATGSPTRWD
MAV_5246|M.avium_104                AALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA-----------
TH_4361|M.thermoresistible__bu      AAAGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR--------------
MAB_3984c|M.abscessus_ATCC_199      AALGLLNPMIAGAAMAMSSVFVVLNSLRLRTFR-----------------
Mb0095|M.bovis_AF2122/97            AAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAP
Rv0092|M.tuberculosis_H37Rv         AAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAP
MUL_4850|M.ulcerans_Agy99           AAAGVLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQTTTSTTEP
MLBr_02000|M.leprae_Br4923          ASSGLLNPLIAGAAMAFSSFFVVSNSLRLSNFG-------------LSQT
                                    *: *:***::******:**.:** ***:*  *                  

Mflv_2244|M.gilvum_PYR-GCK          ---------------------
Mvan_4449|M.vanbaalenii_PYR-1       ---------------------
MSMEG_5014|M.smegmatis_MC2_155      ---------------------
MMAR_0231|M.marinum_M               ATPESPAELSTLPGEPSGCPR
MAV_5246|M.avium_104                ---------------------
TH_4361|M.thermoresistible__bu      ---------------------
MAB_3984c|M.abscessus_ATCC_199      ---------------------
Mb0095|M.bovis_AF2122/97            SSA------------------
Rv0092|M.tuberculosis_H37Rv         SSA------------------
MUL_4850|M.ulcerans_Agy99           GATE-----------------
MLBr_02000|M.leprae_Br4923          SD-------------------