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M. vanbaalenii PYR-1 Mvan_3670 (-)

annotation: heavy metal translocating P-type ATPase
coordinates: 3900118 - 3902466
length: 782

MSLPNHIVGVDQPHSIELSIGGMTCASCAARIEKKLNKIDGVEASVNYATEKAKVDYPNSVDPAVLIAAV
EATGYTATAPAAPNDAAPTDSGPDAGEADSLRSRLLISLVLTVPVIAMSMIPALQFTNWQWLALTLASPV
VVWGALPFHRAAWANARHRAATMDTLISLGVSAAYLWSLWALFIGHAGMPGMRMAFSLLPDAGSETEHIY
LEVAAAVTVFILAGRYFEARAKTRSGAALRALLDMGAKDVAVVRNGTEIRIPTAELSVGDVFVVRPGEKI
ATDGVVTDGSSAVDASMLTGESVPVEVRPGDHVTGATVNAGGRLLVRATRIGADTQLAQMARLVEDAQNG
KASVQRLADRVSAVFVPIVLALSVATLAAWLLTGHSATVAFTAAVAVLIIACPCALGLATPTALMVGTGR
GAQLGILIKGPQVLESTRRVDTIVLDKTGTVTTGRMSLVGVHPGAGQNSDELLEFAGALESASQHPIAEA
IAASAAAGGTLPAVEDFSNHNGYGVTGVVAGHAVLVGRLSWLTDDWSLTAPDDLTSAAEHAQSQGHTPVW
VAWDGAVRGVIVVADTVKGTSADAIGQFRKLGLRPFLLTGDNRRAALAVAAEVGIDPDDVIAEVLPADKV
DTIKCLQAQGRTVAMVGDGVNDAAALVQADLGLAMGTGSDVAIEASDLTLVRGDLRAAADAIRLARSTLR
TIKGNLFWAFAYNVAALPLAALGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTSSASPGQTEDVHVATVPP
GGDEYRRAHTAP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_3670--100% (782)heavy metal translocating P-type ATPase
M. vanbaalenii PYR-1Mvan_4449-0.068.33% (742) heavy metal translocating P-type ATPase
M. vanbaalenii PYR-1Mvan_5853-e-13339.51% (782) heavy metal translocating P-type ATPase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0095ctpA0.052.77% (741) cation transporter P-type ATPase A
M. gilvum PYR-GCKMflv_0912-0.070.27% (750) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv0092ctpA0.052.77% (741) cation transporter P-type ATPase A
M. leprae Br4923MLBr_02000ctpB0.051.85% (756) cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-0.057.09% (748) putative metal transporter ATPase
M. marinum MMMAR_0231ctpA_10.066.49% (743) cation transporter p-type ATPase CtpA_1
M. avium 104MAV_5246-0.063.03% (760) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-0.072.22% (738) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-0.072.70% (751) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_4850ctpA0.050.90% (776) cation transporter p-type ATPase a CtpA

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_3670|M.vanbaalenii_PYR-1       -------MSLPNHIVGVDQPHSIELSIGGMTCASCAARIEKKLNKIDGVE
TH_4361|M.thermoresistible__bu      --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV
MMAR_0231|M.marinum_M               -------MPETTG--LPATLSNVELDIAGMTCASCAMRIEKKLNKLDGVS
MAV_5246|M.avium_104                MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT
Mflv_0912|M.gilvum_PYR-GCK          ------MALMTTSTSTPVSGANVELRIGGMTCASCANRIERKLNKLDGVA
MSMEG_5014|M.smegmatis_MC2_155      ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT
MAB_3984c|M.abscessus_ATCC_199      ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN
Mb0095|M.bovis_AF2122/97            ---MTAAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
Rv0092|M.tuberculosis_H37Rv         ---MTTAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
MUL_4850|M.ulcerans_Agy99           --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR
MLBr_02000|M.leprae_Br4923          ---MTASLVEDTNNN-HESVRRIQLDVAGMLCAACASRVETKLNKIPGVR
                                                            * : ** * :** :::  **:: ** 

Mvan_3670|M.vanbaalenii_PYR-1       ASVNYATEKAKVDYPNSVDPAVLIAAVEATGYTATAPAAPNDAAPTDSGP
TH_4361|M.thermoresistible__bu      ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGA
MMAR_0231|M.marinum_M               ATVNYATERATVTAPAGYDPQILITEVKKAGYAAALPQHRQQPAAAAKTD
MAV_5246|M.avium_104                ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATP------SPPRD
Mflv_0912|M.gilvum_PYR-GCK          ATVNYATEKATVTVPDGYDPALLIAEVEKTGYTATLPTPRAPAPSDASGD
MSMEG_5014|M.smegmatis_MC2_155      ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAPPQPETGGTEQD
MAB_3984c|M.abscessus_ATCC_199      ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD
Mb0095|M.bovis_AF2122/97            AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDPDAD
Rv0092|M.tuberculosis_H37Rv         AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDPDAD
MUL_4850|M.ulcerans_Agy99           ASVNFGTRTAIVEAGEDVDAAALCEVIQQAGYQAEVQPDDGQGAGDSDAE
MLBr_02000|M.leprae_Br4923          ASVNFATRVATIDA-VDVAVDELRQVIEQAGYRATAHAESAVEEIDPDAD
                                    * ** . . * :          *   :. .** *                

Mvan_3670|M.vanbaalenii_PYR-1       DAG---------EADSLRSRLLISLVLTVPVIAMSMIPALQFTNWQWLAL
TH_4361|M.thermoresistible__bu      ATGAAGDD-HDAEAERWRRRLTISAALSIPVVVLSMIPALQFTHWQWLAL
MMAR_0231|M.marinum_M               TH-----G-VDPELASLRGRLVGAVVLAGPVILMAMLPALQFRYWQWASL
MAV_5246|M.avium_104                ----------DPELASLRRRLVTAIALAGPVIAVAMIPALQFQHWHWAAL
Mflv_0912|M.gilvum_PYR-GCK          TPNADG-I-DDPELASLRHRLRASTVLTVPVIAMAMIPALQFTYWQWASL
MSMEG_5014|M.smegmatis_MC2_155      PE--------DRATDALRTRLLVSAVLTVPVIAMAMVPALQFTNWQWLSL
MAB_3984c|M.abscessus_ATCC_199      GHDPHDHMNHDVPDDQLKSRLIGSLILAIPVVVISMAMPLHFSGWEILVA
Mb0095|M.bovis_AF2122/97            HAR--------QLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQWVLS
Rv0092|M.tuberculosis_H37Rv         HAR--------QLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQWVLS
MUL_4850|M.ulcerans_Agy99           HAR--------HLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWEWVLT
MLBr_02000|M.leprae_Br4923          YAR--------NLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGWGYLLT
                                                              ::     ..:  . :*  *     

Mvan_3670|M.vanbaalenii_PYR-1       TLASPVVVWGALPFHRAAWANARHRAATMDTLISLGVSAAYLWSLWALFI
TH_4361|M.thermoresistible__bu      TLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLWALFF
MMAR_0231|M.marinum_M               ALAAPVIVWAGRPFHQAAWVNLKHGTATMDTLISVGTLAAFLWSLYALFL
MAV_5246|M.avium_104                ALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLYALVL
Mflv_0912|M.gilvum_PYR-GCK          TLAAPVIVWAAWPFHRAAWANLRHGTATMDTLISLGTVSAFLWSLYALFF
MSMEG_5014|M.smegmatis_MC2_155      TLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLYALFW
MAB_3984c|M.abscessus_ATCC_199      ALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLWVLFA
Mb0095|M.bovis_AF2122/97            ALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLYTVFG
Rv0092|M.tuberculosis_H37Rv         ALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLYTVFG
MUL_4850|M.ulcerans_Agy99           ALALPVVTWAAWPFHRIALRNARHHGASMETLISVGITAATIWSLYTVFG
MLBr_02000|M.leprae_Br4923          ALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLSTIFV
                                    :*: *:: * . ***  *  * ::  ::*:**:* *  :*  *** .:. 

Mvan_3670|M.vanbaalenii_PYR-1       GHAGMPGMRMAFSLLPDAGSETE------HIYLEVAAAVTVFILAGRYFE
TH_4361|M.thermoresistible__bu      TAAGMPGMTMTFTLLP-ADTGEP------HIYLEVAAAVTTFIIAGRYFE
MMAR_0231|M.marinum_M               GTAGEPGMRHPFELTITPGDGAS------NIYLEVAAGVIAFVLAGRYFE
MAV_5246|M.avium_104                GAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFE
Mflv_0912|M.gilvum_PYR-GCK          GTAGTPGMKHPFELTLAPSHGAA------NIYLEVAAGVTTFILAGRYFE
MSMEG_5014|M.smegmatis_MC2_155      GTAGVPGMTHPFSLVGSRTDGAG------NIYLEVAAGVTTFILAGRYFE
MAB_3984c|M.abscessus_ATCC_199      NAGHTHGDVH--------------------VYFEVVAAVTVFLLAGRFAE
Mb0095|M.bovis_AF2122/97            NHSPIERSGIWQALLGSDA-----------IYFEVAAGVTVFVLVGRYFE
Rv0092|M.tuberculosis_H37Rv         NHSPIERSGIWQALLGSDA-----------IYFEVAAGVTVFVLVGRYFE
MUL_4850|M.ulcerans_Agy99           SHQLADRKGIWQALLGSDA-----------IYFEVAAGVTVFVLAGRYFE
MLBr_02000|M.leprae_Br4923          DKEPRQTHGIWQAILHSDS-----------IYFEVAAGVTVFVLAGRFFE
                                                                  :*:**.*.*  *::.**: *

Mvan_3670|M.vanbaalenii_PYR-1       ARAKTRSGAALRALLDMGAKDVAVVR-NGTEIRIPTAELSVGDVFVVRPG
TH_4361|M.thermoresistible__bu      ARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPIGELHVGDVFVVRPG
MMAR_0231|M.marinum_M               KRSKRRAGAALQALLELGAKDVAVLR-NGAEIRVPVQELTVDDEFVVRPG
MAV_5246|M.avium_104                RRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPIERLAVGDEFVVRPG
Mflv_0912|M.gilvum_PYR-GCK          KRSKRQAGAALRALLNLGAKDVSVLR-DGVETKIAIEELMVGDEFVVRPG
MSMEG_5014|M.smegmatis_MC2_155      AKSKRRASAALRALMELGAKDVAILR-NGAEQRIPIDQLGVGDEFVVRPG
MAB_3984c|M.abscessus_ATCC_199      SRAKRSAGSALRALLSLGAKDVAVLR-GGHETRIPVDQLAVGDEFVVRPG
Mb0095|M.bovis_AF2122/97            ARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPG
Rv0092|M.tuberculosis_H37Rv         ARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPG
MUL_4850|M.ulcerans_Agy99           ARAKSKAGAALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFVVRPG
MLBr_02000|M.leprae_Br4923          ARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFLVRPG
                                     ::*  :.:**:**   .*::* ::   * *  :.  .*   : *:****

Mvan_3670|M.vanbaalenii_PYR-1       EKIATDGVVTDGSSAVDASMLTGESVPVEVRPGDHVTGATVNAGGRLLVR
TH_4361|M.thermoresistible__bu      EKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGHLQVR
MMAR_0231|M.marinum_M               EKIATDGTVVAGSSAVDASMLTGESVPVEVGPGDTVTGATTNAGGRLVVR
MAV_5246|M.avium_104                ERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGRLVVR
Mflv_0912|M.gilvum_PYR-GCK          EKIATDGVVTSGSSAVDASMLTGESVPVEVAAGDTVVGATVNAGGRLVVR
MSMEG_5014|M.smegmatis_MC2_155      EKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGRLVVR
MAB_3984c|M.abscessus_ATCC_199      ERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGRIVVR
Mb0095|M.bovis_AF2122/97            QIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVE
Rv0092|M.tuberculosis_H37Rv         QIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVE
MUL_4850|M.ulcerans_Agy99           QTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGRLIVE
MLBr_02000|M.leprae_Br4923          ETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGRLVIE
                                    : :::** .  * :::* : :***: * ..  .. * *. .   *:: :.

Mvan_3670|M.vanbaalenii_PYR-1       ATRIGADTQLAQMARLVEDAQNGKASVQRLADRVSAVFVPIVLALSVATL
TH_4361|M.thermoresistible__bu      ATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALSALTL
MMAR_0231|M.marinum_M               ATRVGEHTQLAQMAKLVEAAQSGKADVQRLADRVSGVFVPIVIAIAVTTL
MAV_5246|M.avium_104                ATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLAVATL
Mflv_0912|M.gilvum_PYR-GCK          ASRVGSDTQLAQMAELVERAQTGKAEVQRLADRISGVFVPIVIAIAVITL
MSMEG_5014|M.smegmatis_MC2_155      ANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALAVATL
MAB_3984c|M.abscessus_ATCC_199      ANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAISALTF
Mb0095|M.bovis_AF2122/97            AAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTA
Rv0092|M.tuberculosis_H37Rv         AAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTA
MUL_4850|M.ulcerans_Agy99           AAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIAALTA
MLBr_02000|M.leprae_Br4923          ATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMVFVIAGLAG
                                    *  :* .*::* *..**  **  ** .*:****::.**** *: ::  : 

Mvan_3670|M.vanbaalenii_PYR-1       AAWLLTGHS-ATVAFTAAVAVLIIACPCALGLATPTALMVGTGRGAQLGI
TH_4361|M.thermoresistible__bu      AGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGI
MMAR_0231|M.marinum_M               GVWLGAGYP-VSAALTAAVAVLIIACPCALGLATPTALLVGTGRAAALGV
MAV_5246|M.avium_104                AGWLAAGGT-LATALTAAVAVLIIACPCALGLATPTALLVGTGRAAQLGV
Mflv_0912|M.gilvum_PYR-GCK          GAWLGAGFS-VTAAFTAAVAVLVIACPCALGLATPTALLVGTGRGAQMGV
MSMEG_5014|M.smegmatis_MC2_155      GFWLGTGGS-VAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGI
MAB_3984c|M.abscessus_ATCC_199      VAWAALGNS-LASAFTAAVAVLIIACPCALGLATPTAILVGTGRGAQLGV
Mb0095|M.bovis_AF2122/97            AGWLIAGGQ-PDRAVSAALAVLVIACPCALGLATPTAMMVASGRGAQLGI
Rv0092|M.tuberculosis_H37Rv         AGWLIAGGQ-PDRAVSAALAVLVIACPCALGLATPTAMMVASGRGAQLGI
MUL_4850|M.ulcerans_Agy99           AGWLLAGGS-PDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGAQLGI
MLBr_02000|M.leprae_Br4923          ASWLLAGAS-PDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGAQLGI
                                      *          *.:..:.**:*****:********::*.:**.* :*:

Mvan_3670|M.vanbaalenii_PYR-1       LIKGPQVLESTRRVDTIVLDKTGTVTTGRMSLVGVHPGAGQ---NSDELL
TH_4361|M.thermoresistible__bu      LIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL---SETELL
MMAR_0231|M.marinum_M               LIKGPEMLESTRRVDTIVLDKTGTVTTGKMTLLEVITVPDT---DRATAL
MAV_5246|M.avium_104                LIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT---DRATLL
Mflv_0912|M.gilvum_PYR-GCK          LIKGPEVLESTRKVDTVVLDKTGTVTTGKMALVDVIAAPGT---ERAELL
MSMEG_5014|M.smegmatis_MC2_155      LIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE---DRDDVL
MAB_3984c|M.abscessus_ATCC_199      LIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGVADADEIL
Mb0095|M.bovis_AF2122/97            FLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EADQVL
Rv0092|M.tuberculosis_H37Rv         FLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EADQVL
MUL_4850|M.ulcerans_Agy99           FLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DADEVL
MLBr_02000|M.leprae_Br4923          FIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGGW---CSGEVL
                                    ::** . **  . :**:*:*****:* * : :  *    .         *

Mvan_3670|M.vanbaalenii_PYR-1       EFAGALESASQHPIAEAIAASAAAGG-TLPAVEDFSNHNGYGVTGVVAGH
TH_4361|M.thermoresistible__bu      RLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGRVDGH
MMAR_0231|M.marinum_M               RYAGGLEAASEHPIAAAIVKSARAELGALPEPADFANTEGQGVRGIIDGH
MAV_5246|M.avium_104                RYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGRVDGH
Mflv_0912|M.gilvum_PYR-GCK          RLAGALENASEHPIAHAIATAAAEEVGTLPTPEGFANVEGKGVQGVVDGH
MSMEG_5014|M.smegmatis_MC2_155      RVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQGTVEGR
MAB_3984c|M.abscessus_ATCC_199      RIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSGVVDGQ
Mb0095|M.bovis_AF2122/97            ALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGTVSGR
Rv0092|M.tuberculosis_H37Rv         ALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGTVSGR
MUL_4850|M.ulcerans_Agy99           AIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGTVSGR
MLBr_02000|M.leprae_Br4923          ALASAVEAASEHSVATAIVAAYADPR----PVADFVAFAGCGVSGVVAEH
                                      *. :* **:*.:* *:.               *    * ** * :  :

Mvan_3670|M.vanbaalenii_PYR-1       AVLVGRLSWLTDDWSLTAPDDLTSAAEHAQSQGHTPVWVAWDGAVRGVIV
TH_4361|M.thermoresistible__bu      DVRVGRLAWLG----LSAGDRLRNAAAQAEAAGHTPVWVAVDGRIAGVIV
MMAR_0231|M.marinum_M               AVIVGRASLLAD-WAQHLDPDLAAAKDRAESQGKTAVAVGWDGRARAILV
MAV_5246|M.avium_104                AVAIGRPSWLAE-RGLRPDAALAAAAARAEHDGKTVVAVGWDGRARGILA
Mflv_0912|M.gilvum_PYR-GCK          AVVVGRESLLAD-WAQHLSPDLSRAKAGAEAQGKTVVAVGWDGQARGVLV
MSMEG_5014|M.smegmatis_MC2_155      AVVVGRPRLFGD-PEKSLPRKLADAMEAAQAQGRTAVVVGWDGTARGVLV
MAB_3984c|M.abscessus_ATCC_199      EVSI-----------------------EAIEGQNTTAAVSWGGLRRGEIE
Mb0095|M.bovis_AF2122/97            AVRVGKPSWIG---SSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIA
Rv0092|M.tuberculosis_H37Rv         AVRVGKPSWIG---SSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIA
MUL_4850|M.ulcerans_Agy99           SVRVGKPSWIG---SSSSDTALRAALRNAESLGETAVFVEIDGGPCGVIA
MLBr_02000|M.leprae_Br4923          HVKIGKPSWVTR--NAPCDVVLESARREGESRGETVVFVSVDGVACGAVA
                                     * :                        .    .* . *  .*   . : 

Mvan_3670|M.vanbaalenii_PYR-1       VADTVKGTSADAIGQFRKLGLRPFLLTGDNRRAALAVAAEVGIDPDDVIA
TH_4361|M.thermoresistible__bu      VSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID--DVIA
MMAR_0231|M.marinum_M               IADTVKPTSAAAIREFKRLGLTPVLLTGDNPTVARHIADEVGID--EVIA
MAV_5246|M.avium_104                LADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG--EVIS
Mflv_0912|M.gilvum_PYR-GCK          VADTVKPTSAQAISQMRDLGLTPVLLTGDNEAVARQIAAEVGID--TVIA
MSMEG_5014|M.smegmatis_MC2_155      VADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID--DVYA
MAB_3984c|M.abscessus_ATCC_199      VADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAAGDVIA
Mb0095|M.bovis_AF2122/97            VADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--EVIA
Rv0092|M.tuberculosis_H37Rv         VADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--EVIA
MUL_4850|M.ulcerans_Agy99           VADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--EVIA
MLBr_02000|M.leprae_Br4923          IADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGID--TVIA
                                    ::*:**  :  *:  :   *  ..:*****   *   * .:**    * :

Mvan_3670|M.vanbaalenii_PYR-1       EVLPADKVDTIKCLQAQGRTVAMVGDGVNDAAALVQADLGLAMGTGSDVA
TH_4361|M.thermoresistible__bu      GVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTGTDVA
MMAR_0231|M.marinum_M               DVLPAGKVAAVRRLQSEGKIVAMVGDGVNDAAALATADLGLAMGTGADVA
MAV_5246|M.avium_104                GALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTGTDVA
Mflv_0912|M.gilvum_PYR-GCK          EVMPKDKVDVIARLQSEGKTVAMVGDGVNDAPALAQADLGLAMGTGTDVA
MSMEG_5014|M.smegmatis_MC2_155      EVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTGTDVA
MAB_3984c|M.abscessus_ATCC_199      GVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGTGTDAA
Mb0095|M.bovis_AF2122/97            DILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVA
Rv0092|M.tuberculosis_H37Rv         DILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVA
MUL_4850|M.ulcerans_Agy99           NILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRGTDVA
MLBr_02000|M.leprae_Br4923          DMLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGLAMGRGTDVA
                                       *  *.  :  *:  *: ***:***:**..**. **:*:::* *:*.*

Mvan_3670|M.vanbaalenii_PYR-1       IEASDLTLVRGDLRAAADAIRLARSTLRTIKGNLFWAFAYNVAALPLAAL
TH_4361|M.thermoresistible__bu      IEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALPLAAA
MMAR_0231|M.marinum_M               IEAADLTLVRGDLRAAADAIRLSRRTLNTIKTNLFWAFGYNVAALPLAAF
MAV_5246|M.avium_104                IEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPLAAL
Mflv_0912|M.gilvum_PYR-GCK          IEASDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFAYNVAAIPVAAL
MSMEG_5014|M.smegmatis_MC2_155      IEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAALPLAAA
MAB_3984c|M.abscessus_ATCC_199      IEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAIPLAAL
Mb0095|M.bovis_AF2122/97            IGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAA
Rv0092|M.tuberculosis_H37Rv         IGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAA
MUL_4850|M.ulcerans_Agy99           IGAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIPIAAA
MLBr_02000|M.leprae_Br4923          IGAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAIPIASS
                                    * *.*: :* . *  .  *: *.  *: *:: *: ***.** **:*:*: 

Mvan_3670|M.vanbaalenii_PYR-1       GLLNPLIAGAAMAFSSVFVVSNSLRLRRFTSSASPGQTEDVHVATVPPGG
TH_4361|M.thermoresistible__bu      GLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR-----------------
MMAR_0231|M.marinum_M               GLLNPMLAGAAMAFSSVFVVGNSLRLRSFTSVITDAPPATGSPTRWDATP
MAV_5246|M.avium_104                GMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA--------------
Mflv_0912|M.gilvum_PYR-GCK          GMLNPMLAGAAMAFSSVFVVGNSLRLRGFTSTSSAPTH------------
MSMEG_5014|M.smegmatis_MC2_155      GLLNPMLAGAAMAFSSVFVVSNSLRLKRFR--------------------
MAB_3984c|M.abscessus_ATCC_199      GLLNPMIAGAAMAMSSVFVVLNSLRLRTFR--------------------
Mb0095|M.bovis_AF2122/97            GLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA
Rv0092|M.tuberculosis_H37Rv         GLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA
MUL_4850|M.ulcerans_Agy99           GVLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQTTTSTTEPGAT
MLBr_02000|M.leprae_Br4923          GLLNPLIAGAAMAFSSFFVVSNSLRLSNFG-------------LSQTSD-
                                    *:***::******:**.:** ***:*  *                     

Mvan_3670|M.vanbaalenii_PYR-1       DEYRRAHTAP--------
TH_4361|M.thermoresistible__bu      ------------------
MMAR_0231|M.marinum_M               ESPAELSTLPGEPSGCPR
MAV_5246|M.avium_104                ------------------
Mflv_0912|M.gilvum_PYR-GCK          ------------------
MSMEG_5014|M.smegmatis_MC2_155      ------------------
MAB_3984c|M.abscessus_ATCC_199      ------------------
Mb0095|M.bovis_AF2122/97            ------------------
Rv0092|M.tuberculosis_H37Rv         ------------------
MUL_4850|M.ulcerans_Agy99           E-----------------
MLBr_02000|M.leprae_Br4923          ------------------