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M. ulcerans Agy99 MUL_4850 (ctpA)

annotation: cation transporter p-type ATPase a CtpA
coordinates: 5373007 - 5375298
length: 763

MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVRASVNFGTRTAIVEAGEDVDAAA
LCEVIQQAGYQAEVQPDDGQGAGDSDAEHARHLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWEWVLT
ALALPVVTWAAWPFHRIALRNARHHGASMETLISVGITAATIWSLYTVFGSHQLADRKGIWQALLGSDAI
YFEVAAGVTVFVLAGRYFEARAKSKAGAALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFVVRPGQ
TIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGRLIVEAAAVGADTRFAGMVRLVEQAQ
AQKADAQRLADRIASVFVPCVFVIAALTAAGWLLAGGSPDRAFSAAIAVLVIACPCALGLATPTAMMVAS
GRGAQLGIFLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGWDADEVLAIAATVEAASEHSVA
LAIAAATTQHDTVTEFRAIPGRGVSGTVSGRSVRVGKPSWIGSSSSDTALRAALRNAESLGETAVFVEID
GGPCGVIAVADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGIDEVIANILPEGKVDVIEQL
RDRGHVVAMVGDGINDGPALASADLGMAMGRGTDVAIGAADIILVRDNLDVVPLALGLAAATMRTVKLNL
AWAFGYNIAAIPIAAAGVLNPVVAGAAMAFSSFFVVSNSLQLRNFGAATSQTTTSTTEPGATE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4850ctpA-100% (763)cation transporter p-type ATPase a CtpA
M. ulcerans Agy99MUL_4845ctpB0.067.34% (741) cation-transporter p-type ATPase B CtpB
M. ulcerans Agy99MUL_0423ctpVe-15646.16% (717) metal cation transporter p-type ATPase, CtpV

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0095ctpA0.083.87% (744) cation transporter P-type ATPase A
M. gilvum PYR-GCKMflv_0912-0.050.33% (755) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv0092ctpA0.084.01% (744) cation transporter P-type ATPase A
M. leprae Br4923MLBr_01987ctpA0.076.64% (715) putative cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-1e-17447.98% (744) putative metal transporter ATPase
M. marinum MMMAR_0264ctpA0.099.08% (763) cation transporter p-type ATPase a CtpA
M. avium 104MAV_5246-0.050.00% (748) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-0.052.77% (739) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-0.052.49% (743) PUTATIVE heavy metal translocating P-type ATPase
M. vanbaalenii PYR-1Mvan_3670-0.050.90% (776) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0912|M.gilvum_PYR-GCK          MALMT------TSTSTPVSGANVELRIGGMTCASCANRIERKLNKLDGVA
MAV_5246|M.avium_104                MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT
MSMEG_5014|M.smegmatis_MC2_155      ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT
TH_4361|M.thermoresistible__bu      --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV
Mvan_3670|M.vanbaalenii_PYR-1       -------MSLPNHIVGVDQPHSIELSIGGMTCASCAARIEKKLNKIDGVE
MAB_3984c|M.abscessus_ATCC_199      ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN
MUL_4850|M.ulcerans_Agy99           --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR
MMAR_0264|M.marinum_M               --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR
Mb0095|M.bovis_AF2122/97            ---MTAAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
Rv0092|M.tuberculosis_H37Rv         ---MTTAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
MLBr_01987|M.leprae_Br4923          --------------------------------MRAPNGWNNLPNKLSDFS
                                                                      ..   :   *:: .. 

Mflv_0912|M.gilvum_PYR-GCK          ATVNYATEKATVTVPDGYDPALLIAEVEKTGYTATLPTPRAPAPSDASGD
MAV_5246|M.avium_104                ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATPSPPR-------
MSMEG_5014|M.smegmatis_MC2_155      ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAPPQPETGGTEQD
TH_4361|M.thermoresistible__bu      ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGA
Mvan_3670|M.vanbaalenii_PYR-1       ASVNYATEKAKVDYPNSVDPAVLIAAVEATGYTATAPAAPNDAAPTDSGP
MAB_3984c|M.abscessus_ATCC_199      ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD
MUL_4850|M.ulcerans_Agy99           ASVNFGTRTAIVEAGEDVDAAALCEVIQQAGYQAEVQPDDGQGAGDS---
MMAR_0264|M.marinum_M               ASVNFGTRTATVEAGEDVDAAALCEVIQQAGYQAEVQPDDGQGAGDP---
Mb0095|M.bovis_AF2122/97            AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDP---
Rv0092|M.tuberculosis_H37Rv         AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDP---
MLBr_01987|M.leprae_Br4923          TLVNSATRVAAINLSEVTQTAEVCEAVRRAALCTDG--GEALQRRQA---
                                    : ** . . * :          :   :. ..  :                

Mflv_0912|M.gilvum_PYR-GCK          TPNADGI--DDPELASLRHRLRASTVLTVP----VIAMAMIPALQFTYWQ
MAV_5246|M.avium_104                ---------DDPELASLRRRLVTAIALAGP----VIAVAMIPALQFQHWH
MSMEG_5014|M.smegmatis_MC2_155      P--------EDRATDALRTRLLVSAVLTVP----VIAMAMVPALQFTNWQ
TH_4361|M.thermoresistible__bu      ATGAAGDD-HDAEAERWRRRLTISAALSIP----VVVLSMIPALQFTHWQ
Mvan_3670|M.vanbaalenii_PYR-1       DAG---------EADSLRSRLLISLVLTVP----VIAMSMIPALQFTNWQ
MAB_3984c|M.abscessus_ATCC_199      GHDPHDHMNHDVPDDQLKSRLIGSLILAIP----VVVISMAMPLHFSGWE
MUL_4850|M.ulcerans_Agy99           ---------DAEHARHLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWE
MMAR_0264|M.marinum_M               ---------DAEHARHLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWE
Mb0095|M.bovis_AF2122/97            ---------DADHARQLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQ
Rv0092|M.tuberculosis_H37Rv         ---------DADHARQLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQ
MLBr_01987|M.leprae_Br4923          ---------DADNARYLLIRLAVAAALFVPLAHLSVMFAVLPSTHFPGWE
                                                       **  :  *  *     : ..:  . :*  *.

Mflv_0912|M.gilvum_PYR-GCK          WASLTLAAPVIVWAAWPFHRAAWANLRHGTATMDTLISLGTVSAFLWSLY
MAV_5246|M.avium_104                WAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLY
MSMEG_5014|M.smegmatis_MC2_155      WLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLY
TH_4361|M.thermoresistible__bu      WLALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLW
Mvan_3670|M.vanbaalenii_PYR-1       WLALTLASPVVVWGALPFHRAAWANARHRAATMDTLISLGVSAAYLWSLW
MAB_3984c|M.abscessus_ATCC_199      ILVAALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLW
MUL_4850|M.ulcerans_Agy99           WVLTALALPVVTWAAWPFHRIALRNARHHGASMETLISVGITAATIWSLY
MMAR_0264|M.marinum_M               WVLTALALPVVTWAAWPFHRVALRNARHHGASMETLISVGITAATIWSLY
Mb0095|M.bovis_AF2122/97            WVLSALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLY
Rv0092|M.tuberculosis_H37Rv         WVLSALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLY
MLBr_01987|M.leprae_Br4923          WMLTALAIPVVTWAAWPFHRVAIHNARYHGASMETLISTGITAATIWSLY
                                        :*: *:: * . ***  *  * ::  ::*:**:* *  :*  ***:

Mflv_0912|M.gilvum_PYR-GCK          ALFFGTAGTPGMKHPFELTLAP----SHGAA--NIYLEVAAGVTTFILAG
MAV_5246|M.avium_104                ALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAG
MSMEG_5014|M.smegmatis_MC2_155      ALFWGTAGVPGMTHPFSLVGSR----TDGAG--NIYLEVAAGVTTFILAG
TH_4361|M.thermoresistible__bu      ALFFTAAGMPGMTMTFTLLP-AD------TGEPHIYLEVAAAVTTFIIAG
Mvan_3670|M.vanbaalenii_PYR-1       ALFIGHAGMPGMRMAFSLLPDAG------SETEHIYLEVAAAVTVFILAG
MAB_3984c|M.abscessus_ATCC_199      VLFANAGHTHGDVH--------------------VYFEVVAAVTVFLLAG
MUL_4850|M.ulcerans_Agy99           TVFGSHQLADRKGIWQALLGSD-----------AIYFEVAAGVTVFVLAG
MMAR_0264|M.marinum_M               TVFGSHQLADRKGIWQALLGSD-----------AIYFEVAAGVTVFVLAG
Mb0095|M.bovis_AF2122/97            TVFGNHSPIERSGIWQALLGSD-----------AIYFEVAAGVTVFVLVG
Rv0092|M.tuberculosis_H37Rv         TVFGNHSPIERSGIWQALLGSD-----------AIYFEVAAGVTVFVLVG
MLBr_01987|M.leprae_Br4923          TVFGHHQSTEHRGVWRALLGSD-----------AIYFEVAAGITVFVLAG
                                    .:.                               :*:**.*.:* *::.*

Mflv_0912|M.gilvum_PYR-GCK          RYFEKRSKRQAGAALRALLNLGAKDVSVLR-DGVETKIAIEELMVGDEFV
MAV_5246|M.avium_104                RYFERRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPIERLAVGDEFV
MSMEG_5014|M.smegmatis_MC2_155      RYFEAKSKRRASAALRALMELGAKDVAILR-NGAEQRIPIDQLGVGDEFV
TH_4361|M.thermoresistible__bu      RYFEARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPIGELHVGDVFV
Mvan_3670|M.vanbaalenii_PYR-1       RYFEARAKTRSGAALRALLDMGAKDVAVVR-NGTEIRIPTAELSVGDVFV
MAB_3984c|M.abscessus_ATCC_199      RFAESRAKRSAGSALRALLSLGAKDVAVLR-GGHETRIPVDQLAVGDEFV
MUL_4850|M.ulcerans_Agy99           RYFEARAKSKAGAALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFV
MMAR_0264|M.marinum_M               RYFEARAKSKAGSALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFV
Mb0095|M.bovis_AF2122/97            RYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFV
Rv0092|M.tuberculosis_H37Rv         RYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFV
MLBr_01987|M.leprae_Br4923          KYYTARAKSHASIALLALAALSAKDAAVLQPDGSEMVIPANELNEQQRFV
                                    ::   ::*  :. ** **  :.*::.:::   * *  :.  .*   : **

Mflv_0912|M.gilvum_PYR-GCK          VRPGEKIATDGVVTSGSSAVDASMLTGESVPVEVAAGDTVVGATVNAGGR
MAV_5246|M.avium_104                VRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGR
MSMEG_5014|M.smegmatis_MC2_155      VRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGR
TH_4361|M.thermoresistible__bu      VRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGH
Mvan_3670|M.vanbaalenii_PYR-1       VRPGEKIATDGVVTDGSSAVDASMLTGESVPVEVRPGDHVTGATVNAGGR
MAB_3984c|M.abscessus_ATCC_199      VRPGERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGR
MUL_4850|M.ulcerans_Agy99           VRPGQTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGR
MMAR_0264|M.marinum_M               VRPGQTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGR
Mb0095|M.bovis_AF2122/97            VRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGR
Rv0092|M.tuberculosis_H37Rv         VRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGR
MLBr_01987|M.leprae_Br4923          VRPGQTIAADGLVIDGSATVSMSPITGEAKPVRVNPGAQVIGGTVVLNGR
                                    ****: :*:** .  * :::. : :***: * .*  *  * *. .   *:

Mflv_0912|M.gilvum_PYR-GCK          LVVRASRVGSDTQLAQMAELVERAQTGKAEVQRLADRISGVFVPIVIAIA
MAV_5246|M.avium_104                LVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLA
MSMEG_5014|M.smegmatis_MC2_155      LVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALA
TH_4361|M.thermoresistible__bu      LQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALS
Mvan_3670|M.vanbaalenii_PYR-1       LLVRATRIGADTQLAQMARLVEDAQNGKASVQRLADRVSAVFVPIVLALS
MAB_3984c|M.abscessus_ATCC_199      IVVRANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAIS
MUL_4850|M.ulcerans_Agy99           LIVEAAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIA
MMAR_0264|M.marinum_M               LIVEAAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIA
Mb0095|M.bovis_AF2122/97            LIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIA
Rv0092|M.tuberculosis_H37Rv         LIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIA
MLBr_01987|M.leprae_Br4923          LIVEAAAVGDETQLAGMVRLVEQAQQQNANAQRLADRIASVFVPCVFAVA
                                    : *.*  :* :*::* *..**  **  :*..******::.**** *: ::

Mflv_0912|M.gilvum_PYR-GCK          VITLGAWLGAGFS-VTAAFTAAVAVLVIACPCALGLATPTALLVGTGRGA
MAV_5246|M.avium_104                VATLAGWLAAGGT-LATALTAAVAVLIIACPCALGLATPTALLVGTGRAA
MSMEG_5014|M.smegmatis_MC2_155      VATLGFWLGTGGS-VAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
TH_4361|M.thermoresistible__bu      ALTLAGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
Mvan_3670|M.vanbaalenii_PYR-1       VATLAAWLLTGHS-ATVAFTAAVAVLIIACPCALGLATPTALMVGTGRGA
MAB_3984c|M.abscessus_ATCC_199      ALTFVAWAALGNS-LASAFTAAVAVLIIACPCALGLATPTAILVGTGRGA
MUL_4850|M.ulcerans_Agy99           ALTAAGWLLAGGS-PDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGA
MMAR_0264|M.marinum_M               ALTAAGWLLAGGS-PDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGA
Mb0095|M.bovis_AF2122/97            ALTAAGWLIAGGQ-PDRAVSAALAVLVIACPCALGLATPTAMMVASGRGA
Rv0092|M.tuberculosis_H37Rv         ALTAAGWLIAGGQ-PDRAVSAALAVLVIACPCALGLATPTAMMVASGRGA
MLBr_01987|M.leprae_Br4923          ALTAVGWLIAGSG-PDRVFSAAIAVLVIACPCALGLATPTAMMVASGRGA
                                    . *   *          ..:**:***:**************::*.:**.*

Mflv_0912|M.gilvum_PYR-GCK          QMGVLIKGPEVLESTRKVDTVVLDKTGTVTTGKMALVDVIAAPGT---ER
MAV_5246|M.avium_104                QLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT---DR
MSMEG_5014|M.smegmatis_MC2_155      QLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE---DR
TH_4361|M.thermoresistible__bu      QLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL---SE
Mvan_3670|M.vanbaalenii_PYR-1       QLGILIKGPQVLESTRRVDTIVLDKTGTVTTGRMSLVGVHPGAGQ---NS
MAB_3984c|M.abscessus_ATCC_199      QLGVLIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGVADA
MUL_4850|M.ulcerans_Agy99           QLGIFLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DA
MMAR_0264|M.marinum_M               QLGIFLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DA
Mb0095|M.bovis_AF2122/97            QLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EA
Rv0092|M.tuberculosis_H37Rv         QLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EA
MLBr_01987|M.leprae_Br4923          QLGILLKGHESFEATRAVDTVVFDKTGTLTTGQLKVSAVTAAPGW---QA
                                    *:*:::** : :* .: :**:*:*****:*:* : :  *  . *    . 

Mflv_0912|M.gilvum_PYR-GCK          AELLRLAGALENASEHPIAHAIATAAAEEVGTLPTPEGFANVEGKGVQGV
MAV_5246|M.avium_104                ATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGR
MSMEG_5014|M.smegmatis_MC2_155      DDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQGT
TH_4361|M.thermoresistible__bu      TELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGR
Mvan_3670|M.vanbaalenii_PYR-1       DELLEFAGALESASQHPIAEAIAASAAAGG-TLPAVEDFSNHNGYGVTGV
MAB_3984c|M.abscessus_ATCC_199      DEILRIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSGV
MUL_4850|M.ulcerans_Agy99           DEVLAIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGT
MMAR_0264|M.marinum_M               DEVLAIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGT
Mb0095|M.bovis_AF2122/97            DQVLALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGT
Rv0092|M.tuberculosis_H37Rv         DQVLALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGT
MLBr_01987|M.leprae_Br4923          NEVLQMAATVESASEHAVALAIAASTTHRE----PVANFRAVPGHGVSGT
                                      :*  *.::* **:*.:* *:.  :            *    * ** * 

Mflv_0912|M.gilvum_PYR-GCK          VDGHAVVVGRESLLAD-WAQHLSPDLSRAKAGAEAQGKTVVAVGWDGQAR
MAV_5246|M.avium_104                VDGHAVAIGRPSWLAE-RGLRPDAALAAAAARAEHDGKTVVAVGWDGRAR
MSMEG_5014|M.smegmatis_MC2_155      VEGRAVVVGRPRLFGD-PEKSLPRKLADAMEAAQAQGRTAVVVGWDGTAR
TH_4361|M.thermoresistible__bu      VDGHDVRVGRLAWLG----LSAGDRLRNAAAQAEAAGHTPVWVAVDGRIA
Mvan_3670|M.vanbaalenii_PYR-1       VAGHAVLVGRLSWLTDDWSLTAPDDLTSAAEHAQSQGHTPVWVAWDGAVR
MAB_3984c|M.abscessus_ATCC_199      VDGQEVSI-----------------------EAIEGQNTTAAVSWGGLRR
MUL_4850|M.ulcerans_Agy99           VSGRSVRVGKPSWIGS---SSSDTALRAALRNAESLGETAVFVEIDGGPC
MMAR_0264|M.marinum_M               VSGRSVRVGKPSWIGS---SSSDAALRAARRNAESLGETAVFVEIDGAPC
Mb0095|M.bovis_AF2122/97            VSGRAVRVGKPSWIGS---SSCHPNMRAARRHAESLGETAVFVEVDGEPC
Rv0092|M.tuberculosis_H37Rv         VSGRAVRVGKPSWIGS---SSCHPNMRAARRHAESLGETAVFVEVDGEPC
MLBr_01987|M.leprae_Br4923          VAERAVRVGKPSWIAS---RCNSTTLVTARRNAELRGETAVFVEIDGEQC
                                    *  : * :                        *    .* . *  .*   

Mflv_0912|M.gilvum_PYR-GCK          GVLVVADTVKPTSAQAISQMRDLGLTPVLLTGDNEAVARQIAAEVGID--
MAV_5246|M.avium_104                GILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG--
MSMEG_5014|M.smegmatis_MC2_155      GVLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID--
TH_4361|M.thermoresistible__bu      GVIVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID--
Mvan_3670|M.vanbaalenii_PYR-1       GVIVVADTVKGTSADAIGQFRKLGLRPFLLTGDNRRAALAVAAEVGIDPD
MAB_3984c|M.abscessus_ATCC_199      GEIEVADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAAG
MUL_4850|M.ulcerans_Agy99           GVIAVADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--
MMAR_0264|M.marinum_M               GVIAVADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--
Mb0095|M.bovis_AF2122/97            GVIAVADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--
Rv0092|M.tuberculosis_H37Rv         GVIAVADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--
MLBr_01987|M.leprae_Br4923          GVIAVADAVKASAADAVAALHDRGFRTALLTGDNPASAAAVASRIGID--
                                    * : ::*:**  :  *:  :   *  . :*****   *   * .:**   

Mflv_0912|M.gilvum_PYR-GCK          TVIAEVMPKDKVDVIARLQSEGKTVAMVGDGVNDAPALAQADLGLAMGTG
MAV_5246|M.avium_104                EVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTG
MSMEG_5014|M.smegmatis_MC2_155      DVYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTG
TH_4361|M.thermoresistible__bu      DVIAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTG
Mvan_3670|M.vanbaalenii_PYR-1       DVIAEVLPADKVDTIKCLQAQGRTVAMVGDGVNDAAALVQADLGLAMGTG
MAB_3984c|M.abscessus_ATCC_199      DVIAGVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGTG
MUL_4850|M.ulcerans_Agy99           EVIANILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRG
MMAR_0264|M.marinum_M               EVIANILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRG
Mb0095|M.bovis_AF2122/97            EVIADILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRG
Rv0092|M.tuberculosis_H37Rv         EVIADILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRG
MLBr_01987|M.leprae_Br4923          EVIADILPEDKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRG
                                     * :   *  *.: :  *:  *: ***:***:**..**. **:*:::* *

Mflv_0912|M.gilvum_PYR-GCK          TDVAIEASDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFAYNVAAIP
MAV_5246|M.avium_104                TDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIP
MSMEG_5014|M.smegmatis_MC2_155      TDVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAALP
TH_4361|M.thermoresistible__bu      TDVAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALP
Mvan_3670|M.vanbaalenii_PYR-1       SDVAIEASDLTLVRGDLRAAADAIRLARSTLRTIKGNLFWAFAYNVAALP
MAB_3984c|M.abscessus_ATCC_199      TDAAIEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAIP
MUL_4850|M.ulcerans_Agy99           TDVAIGAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIP
MMAR_0264|M.marinum_M               TDVAIGAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIP
Mb0095|M.bovis_AF2122/97            TDVAIGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIP
Rv0092|M.tuberculosis_H37Rv         TDVAIGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIP
MLBr_01987|M.leprae_Br4923          TDVAIGAADIILVRDNLDVVPITLDLAAATMRTIKFNMVWAFGYNIAAIP
                                    :*.** *.*: :* ..*  .  :: *.  *: *:* *: ***.** **:*

Mflv_0912|M.gilvum_PYR-GCK          VAALGMLNPMLAGAAMAFSSVFVVGNSLRLRGFTSTSSAPTH--------
MAV_5246|M.avium_104                LAALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA----------
MSMEG_5014|M.smegmatis_MC2_155      LAAAGLLNPMLAGAAMAFSSVFVVSNSLRLKRFR----------------
TH_4361|M.thermoresistible__bu      LAAAGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR-------------
Mvan_3670|M.vanbaalenii_PYR-1       LAALGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTSSASPGQTEDVHVATV
MAB_3984c|M.abscessus_ATCC_199      LAALGLLNPMIAGAAMAMSSVFVVLNSLRLRTFR----------------
MUL_4850|M.ulcerans_Agy99           IAAAGVLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQT------
MMAR_0264|M.marinum_M               IAAAGVLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQT------
Mb0095|M.bovis_AF2122/97            VAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVG------
Rv0092|M.tuberculosis_H37Rv         VAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVG------
MLBr_01987|M.leprae_Br4923          IAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRNFGAILSCGTSRHRTVKRW
                                    :** *:***::******:**.:** ***:*: *                 

Mflv_0912|M.gilvum_PYR-GCK          ------------------------------------
MAV_5246|M.avium_104                ------------------------------------
MSMEG_5014|M.smegmatis_MC2_155      ------------------------------------
TH_4361|M.thermoresistible__bu      ------------------------------------
Mvan_3670|M.vanbaalenii_PYR-1       PPGGDEYRRAHTAP----------------------
MAB_3984c|M.abscessus_ATCC_199      ------------------------------------
MUL_4850|M.ulcerans_Agy99           -TTSTTEPGATE------------------------
MMAR_0264|M.marinum_M               -TTSTTEPGATE------------------------
Mb0095|M.bovis_AF2122/97            -GPQMTAPSSA-------------------------
Rv0092|M.tuberculosis_H37Rv         -GPQMTAPSSA-------------------------
MLBr_01987|M.leprae_Br4923          RCPPPTRLRSTACSPVDASPLRPVAHRTGVKPPTHR