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M. bovis AF2122 / 97 Mb0095 (ctpA)

annotation: cation transporter P-type ATPase A
coordinates: 100618 - 102903
length: 761

MTAAVTGEHHASVQRIQLRISGMSCSACAHRVESTLNKLPGVRAAVNFGTRVATIDTSEAVDAAALCQAV
RRAGYQADLCTDDGRSASDPDADHARQLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQWVLSALALP
VVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLYTVFGNHSPIERSGIWQALLGSDAIYFEVA
AGVTVFVLVGRYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPGQIVAAD
GLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVEAAAVGADTQFAGMVRLVEQAQAQKAD
AQRLADRISSVFVPAVLVIAALTAAGWLIAGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASGRGAQ
LGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGWEADQVLALAATVEAASEHSVALAIAA
ATTRRDAVTDFRAIPGRGVSGTVSGRAVRVGKPSWIGSSSCHPNMRAARRHAESLGETAVFVEVDGEPCG
VIAVADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGIDEVIADILPEGKVDVIEQLRDRGH
VVAMVGDGINDGPALARADLGMAIGRGTDVAIGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFG
YNIAAIPVAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0095ctpA-100% (761)cation transporter P-type ATPase A
M. bovis AF2122 / 97Mb0106cctpB0.068.29% (741) cation-transporter P-type ATPase B
M. bovis AF2122 / 97Mb0994ctpVe-15948.13% (667) metal cation transporter P-type ATPase CtpV

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0912-0.051.07% (748) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv0092ctpA0.099.87% (761) cation transporter P-type ATPase A
M. leprae Br4923MLBr_01987ctpA0.077.20% (715) putative cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-1e-17347.74% (752) putative metal transporter ATPase
M. marinum MMMAR_0264ctpA0.084.54% (744) cation transporter p-type ATPase a CtpA
M. avium 104MAV_5246-0.049.73% (752) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-0.051.76% (740) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-0.052.41% (746) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_4850ctpA0.083.87% (744) cation transporter p-type ATPase a CtpA
M. vanbaalenii PYR-1Mvan_3670-0.052.77% (741) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0912|M.gilvum_PYR-GCK          MALMT------TSTSTPVSGANVELRIGGMTCASCANRIERKLNKLDGVA
MAV_5246|M.avium_104                MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT
MSMEG_5014|M.smegmatis_MC2_155      ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT
TH_4361|M.thermoresistible__bu      --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV
Mvan_3670|M.vanbaalenii_PYR-1       -------MSLPNHIVGVDQPHSIELSIGGMTCASCAARIEKKLNKIDGVE
MAB_3984c|M.abscessus_ATCC_199      ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN
Mb0095|M.bovis_AF2122/97            ---MTAAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
Rv0092|M.tuberculosis_H37Rv         ---MTTAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
MMAR_0264|M.marinum_M               --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR
MUL_4850|M.ulcerans_Agy99           --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR
MLBr_01987|M.leprae_Br4923          --------------------------------MRAPNGWNNLPNKLSDFS
                                                                      ..   :   *:: .. 

Mflv_0912|M.gilvum_PYR-GCK          ATVNYATEKATVTVPDGYDPALLIAEVEKTGYTATLPTPRAPAPSDASGD
MAV_5246|M.avium_104                ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATPSPPR-------
MSMEG_5014|M.smegmatis_MC2_155      ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAPPQPETGGTEQD
TH_4361|M.thermoresistible__bu      ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGA
Mvan_3670|M.vanbaalenii_PYR-1       ASVNYATEKAKVDYPNSVDPAVLIAAVEATGYTATAPAAPNDAAPTDSGP
MAB_3984c|M.abscessus_ATCC_199      ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD
Mb0095|M.bovis_AF2122/97            AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDP---
Rv0092|M.tuberculosis_H37Rv         AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDP---
MMAR_0264|M.marinum_M               ASVNFGTRTATVEAGEDVDAAALCEVIQQAGYQAEVQPDDGQGAGDP---
MUL_4850|M.ulcerans_Agy99           ASVNFGTRTAIVEAGEDVDAAALCEVIQQAGYQAEVQPDDGQGAGDS---
MLBr_01987|M.leprae_Br4923          TLVNSATRVAAINLSEVTQTAEVCEAVRRAALCTDG--GEALQRRQA---
                                    : ** . . * :          :   :. ..  :                

Mflv_0912|M.gilvum_PYR-GCK          TPNADGI--DDPELASLRHRLRASTVLTVP----VIAMAMIPALQFTYWQ
MAV_5246|M.avium_104                ---------DDPELASLRRRLVTAIALAGP----VIAVAMIPALQFQHWH
MSMEG_5014|M.smegmatis_MC2_155      P--------EDRATDALRTRLLVSAVLTVP----VIAMAMVPALQFTNWQ
TH_4361|M.thermoresistible__bu      ATGAAGDD-HDAEAERWRRRLTISAALSIP----VVVLSMIPALQFTHWQ
Mvan_3670|M.vanbaalenii_PYR-1       DAG---------EADSLRSRLLISLVLTVP----VIAMSMIPALQFTNWQ
MAB_3984c|M.abscessus_ATCC_199      GHDPHDHMNHDVPDDQLKSRLIGSLILAIP----VVVISMAMPLHFSGWE
Mb0095|M.bovis_AF2122/97            ---------DADHARQLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQ
Rv0092|M.tuberculosis_H37Rv         ---------DADHARQLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQ
MMAR_0264|M.marinum_M               ---------DAEHARHLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWE
MUL_4850|M.ulcerans_Agy99           ---------DAEHARHLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWE
MLBr_01987|M.leprae_Br4923          ---------DADNARYLLIRLAVAAALFVPLAHLSVMFAVLPSTHFPGWE
                                                       **  :  *  *     : ..:  . :*  *.

Mflv_0912|M.gilvum_PYR-GCK          WASLTLAAPVIVWAAWPFHRAAWANLRHGTATMDTLISLGTVSAFLWSLY
MAV_5246|M.avium_104                WAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLY
MSMEG_5014|M.smegmatis_MC2_155      WLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLY
TH_4361|M.thermoresistible__bu      WLALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLW
Mvan_3670|M.vanbaalenii_PYR-1       WLALTLASPVVVWGALPFHRAAWANARHRAATMDTLISLGVSAAYLWSLW
MAB_3984c|M.abscessus_ATCC_199      ILVAALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLW
Mb0095|M.bovis_AF2122/97            WVLSALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLY
Rv0092|M.tuberculosis_H37Rv         WVLSALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLY
MMAR_0264|M.marinum_M               WVLTALALPVVTWAAWPFHRVALRNARHHGASMETLISVGITAATIWSLY
MUL_4850|M.ulcerans_Agy99           WVLTALALPVVTWAAWPFHRIALRNARHHGASMETLISVGITAATIWSLY
MLBr_01987|M.leprae_Br4923          WMLTALAIPVVTWAAWPFHRVAIHNARYHGASMETLISTGITAATIWSLY
                                        :*: *:: * . ***  *  * ::  ::*:**:* *  :*  ***:

Mflv_0912|M.gilvum_PYR-GCK          ALFFGTAGTPGMKHPFELTLAP----SHGAA--NIYLEVAAGVTTFILAG
MAV_5246|M.avium_104                ALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAG
MSMEG_5014|M.smegmatis_MC2_155      ALFWGTAGVPGMTHPFSLVGSR----TDGAG--NIYLEVAAGVTTFILAG
TH_4361|M.thermoresistible__bu      ALFFTAAGMPGMTMTFTLLP-AD------TGEPHIYLEVAAAVTTFIIAG
Mvan_3670|M.vanbaalenii_PYR-1       ALFIGHAGMPGMRMAFSLLPDAG------SETEHIYLEVAAAVTVFILAG
MAB_3984c|M.abscessus_ATCC_199      VLFANAGHTHGDVH--------------------VYFEVVAAVTVFLLAG
Mb0095|M.bovis_AF2122/97            TVFGNHSPIERSGIWQALLGSD-----------AIYFEVAAGVTVFVLVG
Rv0092|M.tuberculosis_H37Rv         TVFGNHSPIERSGIWQALLGSD-----------AIYFEVAAGVTVFVLVG
MMAR_0264|M.marinum_M               TVFGSHQLADRKGIWQALLGSD-----------AIYFEVAAGVTVFVLAG
MUL_4850|M.ulcerans_Agy99           TVFGSHQLADRKGIWQALLGSD-----------AIYFEVAAGVTVFVLAG
MLBr_01987|M.leprae_Br4923          TVFGHHQSTEHRGVWRALLGSD-----------AIYFEVAAGITVFVLAG
                                    .:.                               :*:**.*.:* *::.*

Mflv_0912|M.gilvum_PYR-GCK          RYFEKRSKRQAGAALRALLNLGAKDVSVLR-DGVETKIAIEELMVGDEFV
MAV_5246|M.avium_104                RYFERRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPIERLAVGDEFV
MSMEG_5014|M.smegmatis_MC2_155      RYFEAKSKRRASAALRALMELGAKDVAILR-NGAEQRIPIDQLGVGDEFV
TH_4361|M.thermoresistible__bu      RYFEARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPIGELHVGDVFV
Mvan_3670|M.vanbaalenii_PYR-1       RYFEARAKTRSGAALRALLDMGAKDVAVVR-NGTEIRIPTAELSVGDVFV
MAB_3984c|M.abscessus_ATCC_199      RFAESRAKRSAGSALRALLSLGAKDVAVLR-GGHETRIPVDQLAVGDEFV
Mb0095|M.bovis_AF2122/97            RYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFV
Rv0092|M.tuberculosis_H37Rv         RYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFV
MMAR_0264|M.marinum_M               RYFEARAKSKAGSALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFV
MUL_4850|M.ulcerans_Agy99           RYFEARAKSKAGAALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFV
MLBr_01987|M.leprae_Br4923          KYYTARAKSHASIALLALAALSAKDAAVLQPDGSEMVIPANELNEQQRFV
                                    ::   ::*  :. ** **  :.*::.:::   * *  :.  .*   : **

Mflv_0912|M.gilvum_PYR-GCK          VRPGEKIATDGVVTSGSSAVDASMLTGESVPVEVAAGDTVVGATVNAGGR
MAV_5246|M.avium_104                VRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGR
MSMEG_5014|M.smegmatis_MC2_155      VRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGR
TH_4361|M.thermoresistible__bu      VRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGH
Mvan_3670|M.vanbaalenii_PYR-1       VRPGEKIATDGVVTDGSSAVDASMLTGESVPVEVRPGDHVTGATVNAGGR
MAB_3984c|M.abscessus_ATCC_199      VRPGERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGR
Mb0095|M.bovis_AF2122/97            VRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGR
Rv0092|M.tuberculosis_H37Rv         VRPGQIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGR
MMAR_0264|M.marinum_M               VRPGQTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGR
MUL_4850|M.ulcerans_Agy99           VRPGQTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGR
MLBr_01987|M.leprae_Br4923          VRPGQTIAADGLVIDGSATVSMSPITGEAKPVRVNPGAQVIGGTVVLNGR
                                    ****: :*:** .  * :::. : :***: * .*  *  * *. .   *:

Mflv_0912|M.gilvum_PYR-GCK          LVVRASRVGSDTQLAQMAELVERAQTGKAEVQRLADRISGVFVPIVIAIA
MAV_5246|M.avium_104                LVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLA
MSMEG_5014|M.smegmatis_MC2_155      LVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALA
TH_4361|M.thermoresistible__bu      LQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALS
Mvan_3670|M.vanbaalenii_PYR-1       LLVRATRIGADTQLAQMARLVEDAQNGKASVQRLADRVSAVFVPIVLALS
MAB_3984c|M.abscessus_ATCC_199      IVVRANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAIS
Mb0095|M.bovis_AF2122/97            LIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIA
Rv0092|M.tuberculosis_H37Rv         LIVEAAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIA
MMAR_0264|M.marinum_M               LIVEAAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIA
MUL_4850|M.ulcerans_Agy99           LIVEAAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIA
MLBr_01987|M.leprae_Br4923          LIVEAAAVGDETQLAGMVRLVEQAQQQNANAQRLADRIASVFVPCVFAVA
                                    : *.*  :* :*::* *..**  **  :*..******::.**** *: ::

Mflv_0912|M.gilvum_PYR-GCK          VITLGAWLGAGFS-VTAAFTAAVAVLVIACPCALGLATPTALLVGTGRGA
MAV_5246|M.avium_104                VATLAGWLAAGGT-LATALTAAVAVLIIACPCALGLATPTALLVGTGRAA
MSMEG_5014|M.smegmatis_MC2_155      VATLGFWLGTGGS-VAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
TH_4361|M.thermoresistible__bu      ALTLAGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
Mvan_3670|M.vanbaalenii_PYR-1       VATLAAWLLTGHS-ATVAFTAAVAVLIIACPCALGLATPTALMVGTGRGA
MAB_3984c|M.abscessus_ATCC_199      ALTFVAWAALGNS-LASAFTAAVAVLIIACPCALGLATPTAILVGTGRGA
Mb0095|M.bovis_AF2122/97            ALTAAGWLIAGGQ-PDRAVSAALAVLVIACPCALGLATPTAMMVASGRGA
Rv0092|M.tuberculosis_H37Rv         ALTAAGWLIAGGQ-PDRAVSAALAVLVIACPCALGLATPTAMMVASGRGA
MMAR_0264|M.marinum_M               ALTAAGWLLAGGS-PDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGA
MUL_4850|M.ulcerans_Agy99           ALTAAGWLLAGGS-PDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGA
MLBr_01987|M.leprae_Br4923          ALTAVGWLIAGSG-PDRVFSAAIAVLVIACPCALGLATPTAMMVASGRGA
                                    . *   *          ..:**:***:**************::*.:**.*

Mflv_0912|M.gilvum_PYR-GCK          QMGVLIKGPEVLESTRKVDTVVLDKTGTVTTGKMALVDVIAAPGT---ER
MAV_5246|M.avium_104                QLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT---DR
MSMEG_5014|M.smegmatis_MC2_155      QLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE---DR
TH_4361|M.thermoresistible__bu      QLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL---SE
Mvan_3670|M.vanbaalenii_PYR-1       QLGILIKGPQVLESTRRVDTIVLDKTGTVTTGRMSLVGVHPGAGQ---NS
MAB_3984c|M.abscessus_ATCC_199      QLGVLIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGVADA
Mb0095|M.bovis_AF2122/97            QLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EA
Rv0092|M.tuberculosis_H37Rv         QLGIFLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EA
MMAR_0264|M.marinum_M               QLGIFLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DA
MUL_4850|M.ulcerans_Agy99           QLGIFLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DA
MLBr_01987|M.leprae_Br4923          QLGILLKGHESFEATRAVDTVVFDKTGTLTTGQLKVSAVTAAPGW---QA
                                    *:*:::** : :* .: :**:*:*****:*:* : :  *  . *    . 

Mflv_0912|M.gilvum_PYR-GCK          AELLRLAGALENASEHPIAHAIATAAAEEVGTLPTPEGFANVEGKGVQGV
MAV_5246|M.avium_104                ATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGR
MSMEG_5014|M.smegmatis_MC2_155      DDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQGT
TH_4361|M.thermoresistible__bu      TELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGR
Mvan_3670|M.vanbaalenii_PYR-1       DELLEFAGALESASQHPIAEAIAASAAAGG-TLPAVEDFSNHNGYGVTGV
MAB_3984c|M.abscessus_ATCC_199      DEILRIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSGV
Mb0095|M.bovis_AF2122/97            DQVLALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGT
Rv0092|M.tuberculosis_H37Rv         DQVLALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGT
MMAR_0264|M.marinum_M               DEVLAIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGT
MUL_4850|M.ulcerans_Agy99           DEVLAIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGT
MLBr_01987|M.leprae_Br4923          NEVLQMAATVESASEHAVALAIAASTTHRE----PVANFRAVPGHGVSGT
                                      :*  *.::* **:*.:* *:.  :            *    * ** * 

Mflv_0912|M.gilvum_PYR-GCK          VDGHAVVVGRESLLAD-WAQHLSPDLSRAKAGAEAQGKTVVAVGWDGQAR
MAV_5246|M.avium_104                VDGHAVAIGRPSWLAE-RGLRPDAALAAAAARAEHDGKTVVAVGWDGRAR
MSMEG_5014|M.smegmatis_MC2_155      VEGRAVVVGRPRLFGD-PEKSLPRKLADAMEAAQAQGRTAVVVGWDGTAR
TH_4361|M.thermoresistible__bu      VDGHDVRVGRLAWLG----LSAGDRLRNAAAQAEAAGHTPVWVAVDGRIA
Mvan_3670|M.vanbaalenii_PYR-1       VAGHAVLVGRLSWLTDDWSLTAPDDLTSAAEHAQSQGHTPVWVAWDGAVR
MAB_3984c|M.abscessus_ATCC_199      VDGQEVSI-----------------------EAIEGQNTTAAVSWGGLRR
Mb0095|M.bovis_AF2122/97            VSGRAVRVGKPSWIGS---SSCHPNMRAARRHAESLGETAVFVEVDGEPC
Rv0092|M.tuberculosis_H37Rv         VSGRAVRVGKPSWIGS---SSCHPNMRAARRHAESLGETAVFVEVDGEPC
MMAR_0264|M.marinum_M               VSGRSVRVGKPSWIGS---SSSDAALRAARRNAESLGETAVFVEIDGAPC
MUL_4850|M.ulcerans_Agy99           VSGRSVRVGKPSWIGS---SSSDTALRAALRNAESLGETAVFVEIDGGPC
MLBr_01987|M.leprae_Br4923          VAERAVRVGKPSWIAS---RCNSTTLVTARRNAELRGETAVFVEIDGEQC
                                    *  : * :                        *    .* . *  .*   

Mflv_0912|M.gilvum_PYR-GCK          GVLVVADTVKPTSAQAISQMRDLGLTPVLLTGDNEAVARQIAAEVGID--
MAV_5246|M.avium_104                GILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG--
MSMEG_5014|M.smegmatis_MC2_155      GVLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID--
TH_4361|M.thermoresistible__bu      GVIVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID--
Mvan_3670|M.vanbaalenii_PYR-1       GVIVVADTVKGTSADAIGQFRKLGLRPFLLTGDNRRAALAVAAEVGIDPD
MAB_3984c|M.abscessus_ATCC_199      GEIEVADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAAG
Mb0095|M.bovis_AF2122/97            GVIAVADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--
Rv0092|M.tuberculosis_H37Rv         GVIAVADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--
MMAR_0264|M.marinum_M               GVIAVADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--
MUL_4850|M.ulcerans_Agy99           GVIAVADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--
MLBr_01987|M.leprae_Br4923          GVIAVADAVKASAADAVAALHDRGFRTALLTGDNPASAAAVASRIGID--
                                    * : ::*:**  :  *:  :   *  . :*****   *   * .:**   

Mflv_0912|M.gilvum_PYR-GCK          TVIAEVMPKDKVDVIARLQSEGKTVAMVGDGVNDAPALAQADLGLAMGTG
MAV_5246|M.avium_104                EVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTG
MSMEG_5014|M.smegmatis_MC2_155      DVYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTG
TH_4361|M.thermoresistible__bu      DVIAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTG
Mvan_3670|M.vanbaalenii_PYR-1       DVIAEVLPADKVDTIKCLQAQGRTVAMVGDGVNDAAALVQADLGLAMGTG
MAB_3984c|M.abscessus_ATCC_199      DVIAGVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGTG
Mb0095|M.bovis_AF2122/97            EVIADILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRG
Rv0092|M.tuberculosis_H37Rv         EVIADILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRG
MMAR_0264|M.marinum_M               EVIANILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRG
MUL_4850|M.ulcerans_Agy99           EVIANILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRG
MLBr_01987|M.leprae_Br4923          EVIADILPEDKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRG
                                     * :   *  *.: :  *:  *: ***:***:**..**. **:*:::* *

Mflv_0912|M.gilvum_PYR-GCK          TDVAIEASDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFAYNVAAIP
MAV_5246|M.avium_104                TDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIP
MSMEG_5014|M.smegmatis_MC2_155      TDVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAALP
TH_4361|M.thermoresistible__bu      TDVAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALP
Mvan_3670|M.vanbaalenii_PYR-1       SDVAIEASDLTLVRGDLRAAADAIRLARSTLRTIKGNLFWAFAYNVAALP
MAB_3984c|M.abscessus_ATCC_199      TDAAIEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAIP
Mb0095|M.bovis_AF2122/97            TDVAIGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIP
Rv0092|M.tuberculosis_H37Rv         TDVAIGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIP
MMAR_0264|M.marinum_M               TDVAIGAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIP
MUL_4850|M.ulcerans_Agy99           TDVAIGAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIP
MLBr_01987|M.leprae_Br4923          TDVAIGAADIILVRDNLDVVPITLDLAAATMRTIKFNMVWAFGYNIAAIP
                                    :*.** *.*: :* ..*  .  :: *.  *: *:* *: ***.** **:*

Mflv_0912|M.gilvum_PYR-GCK          VAALGMLNPMLAGAAMAFSSVFVVGNSLRLRGFTSTSSAPTH--------
MAV_5246|M.avium_104                LAALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA----------
MSMEG_5014|M.smegmatis_MC2_155      LAAAGLLNPMLAGAAMAFSSVFVVSNSLRLKRFR----------------
TH_4361|M.thermoresistible__bu      LAAAGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR-------------
Mvan_3670|M.vanbaalenii_PYR-1       LAALGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTSSASPGQTEDVHVATV
MAB_3984c|M.abscessus_ATCC_199      LAALGLLNPMIAGAAMAMSSVFVVLNSLRLRTFR----------------
Mb0095|M.bovis_AF2122/97            VAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVG------
Rv0092|M.tuberculosis_H37Rv         VAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVG------
MMAR_0264|M.marinum_M               IAAAGVLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQT------
MUL_4850|M.ulcerans_Agy99           IAAAGVLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQT------
MLBr_01987|M.leprae_Br4923          IAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRNFGAILSCGTSRHRTVKRW
                                    :** *:***::******:**.:** ***:*: *                 

Mflv_0912|M.gilvum_PYR-GCK          ------------------------------------
MAV_5246|M.avium_104                ------------------------------------
MSMEG_5014|M.smegmatis_MC2_155      ------------------------------------
TH_4361|M.thermoresistible__bu      ------------------------------------
Mvan_3670|M.vanbaalenii_PYR-1       PPGGDEYRRAHTAP----------------------
MAB_3984c|M.abscessus_ATCC_199      ------------------------------------
Mb0095|M.bovis_AF2122/97            -GPQMTAPSSA-------------------------
Rv0092|M.tuberculosis_H37Rv         -GPQMTAPSSA-------------------------
MMAR_0264|M.marinum_M               -TTSTTEPGATE------------------------
MUL_4850|M.ulcerans_Agy99           -TTSTTEPGATE------------------------
MLBr_01987|M.leprae_Br4923          RCPPPTRLRSTACSPVDASPLRPVAHRTGVKPPTHR