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TASLVEDTNNNHESVRRIQLDVAGMLCAACASRVETKLNKIPGVRASVNFATRVATIDAVDVAVDELRQV IEQAGYRATAHAESAVEEIDPDADYARNLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGWGYLLTALAA PIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLSTIFVDKEPRQTHGIWQAILHSDSIYFEV AAGVTVFVLAGRFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFLVRPGETITA DGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGRLVIEATAVGGDTQFAAMVRLVEDAQVQKA RVQHLADRIAAVFVPMVFVIAGLAGASWLLAGASPDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGA QLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGGWCSGEVLALASAVEAASEHSVATAIV AAYADPRPVADFVAFAGCGVSGVVAEHHVKIGKPSWVTRNAPCDVVLESARREGESRGETVVFVSVDGVA CGAVAIADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGIDTVIADMLPEAKVDVIQRLRDQ GHTVAMVGDGINDGPALACADLGLAMGRGTDVAIGAADLILVRDSLGVVPVALDLARATMRTIRINMIWA FGYNVAAIPIASSGLLNPLIAGAAMAFSSFFVVSNSLRLSNFGLSQTSD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_02000 | ctpB | - | 100% (750) | cation-transporting ATPase |
M. leprae Br4923 | MLBr_01987 | ctpA | 0.0 | 63.60% (706) | putative cation-transporting ATPase |
M. leprae Br4923 | MLBr_00747 | ctpC | 1e-78 | 34.42% (552) | putative cation transport ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0106c | ctpB | 0.0 | 77.13% (752) | cation-transporter P-type ATPase B |
M. gilvum PYR-GCK | Mflv_2244 | - | 0.0 | 48.99% (739) | heavy metal translocating P-type ATPase |
M. tuberculosis H37Rv | Rv0103c | ctpB | 0.0 | 77.13% (752) | cation-transporter P-type ATPase B |
M. abscessus ATCC 19977 | MAB_3984c | - | 1e-165 | 46.45% (760) | putative metal transporter ATPase |
M. marinum M | MMAR_0269 | ctpB | 0.0 | 79.32% (730) | cation-transporter p-type ATPase B CtpB |
M. avium 104 | MAV_5246 | - | 1e-174 | 47.72% (746) | copper-translocating P-type ATPase |
M. smegmatis MC2 155 | MSMEG_5014 | - | 0.0 | 50.07% (741) | copper-translocating P-type ATPase |
M. thermoresistible (build 8) | TH_4361 | - | 0.0 | 50.26% (756) | PUTATIVE heavy metal translocating P-type ATPase |
M. ulcerans Agy99 | MUL_4845 | ctpB | 0.0 | 78.77% (730) | cation-transporter p-type ATPase B CtpB |
M. vanbaalenii PYR-1 | Mvan_3670 | - | 0.0 | 51.85% (756) | heavy metal translocating P-type ATPase |
CLUSTAL 2.0.9 multiple sequence alignment TH_4361|M.thermoresistible__bu --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV Mvan_3670|M.vanbaalenii_PYR-1 -------MSLPNHIVGVDQPHSIELSIGGMTCASCAARIEKKLNKIDGVE Mflv_2244|M.gilvum_PYR-GCK -------------------MNTLELSIGGMTCASCAARVEKKLNKLDGVT MSMEG_5014|M.smegmatis_MC2_155 ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT MAV_5246|M.avium_104 MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT MAB_3984c|M.abscessus_ATCC_199 ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN Mb0106c|M.bovis_AF2122/97 ----MAAPVVGDAD--LQSVRRIRLDVSGMSCAACASRVETKLNKIPGVR Rv0103c|M.tuberculosis_H37Rv ----MAAPVVGDAD--LQSVRRIRLDVLGMSCAACASRVETKLNKIPGVR MMAR_0269|M.marinum_M ----MAAPITGDLD--LGSARRIQLDVSGMSCAACASRVETKLNKVPGVR MUL_4845|M.ulcerans_Agy99 ----MAAPITGDLD--LGSARRIQLDVSGMSCAACASRVETKLNKVPGVR MLBr_02000|M.leprae_Br4923 ----MTASLVEDTNNNHESVRRIQLDVAGMLCAACASRVETKLNKIPGVR * : ** **:**:*:* **:: ** TH_4361|M.thermoresistible__bu ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGA Mvan_3670|M.vanbaalenii_PYR-1 ASVNYATEKAKVDYPNSVDPAVLIAAVEATGYTATAPAAPNDAAPTDSGP Mflv_2244|M.gilvum_PYR-GCK ATVNYATEKARVEFGDNVSTDQLVSAVESAGYQAALPEPPNP----PDVE MSMEG_5014|M.smegmatis_MC2_155 ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAPPQPETGGTEQD MAV_5246|M.avium_104 ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATPSPP-----RDD MAB_3984c|M.abscessus_ATCC_199 ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD Mb0106c|M.bovis_AF2122/97 ASVNFATRVATIDAVG-MAADELCGVVEKAGYHAAPHTETTVLDKRTKDP Rv0103c|M.tuberculosis_H37Rv ASVNFATRVATIDAVG-MAADELCGVVEKAGYHAAPHTETTVLDKRTKDP MMAR_0269|M.marinum_M ASVNFATRVATIDAVD-VAADQLCELVEKAGYQAVPHAESAADDR---DP MUL_4845|M.ulcerans_Agy99 ASVNFATRVATIDAVD-VAADELCELVEKAGYQAVPHAESAADDR---DP MLBr_02000|M.leprae_Br4923 ASVNFATRVATIDAVD-VAVDELRQVIEQAGYRATAHAESAVEEI---DP * ** * . * : * :* .** * TH_4361|M.thermoresistible__bu ATGAAGDD-HDAEAERWRRRLTISAALSIPVVVLS----MIPALQFTHWQ Mvan_3670|M.vanbaalenii_PYR-1 DAG---------EADSLRSRLLISLVLTVPVIAMS----MIPALQFTNWQ Mflv_2244|M.gilvum_PYR-GCK PAD---------PTAALRRRLIICVALSVPVIAMA----MAPPLQFTYWQ MSMEG_5014|M.smegmatis_MC2_155 PEDR--------ATDALRTRLLVSAVLTVPVIAMA----MVPALQFTNWQ MAV_5246|M.avium_104 P-----------ELASLRRRLVTAIALAGPVIAVA----MIPALQFQHWH MAB_3984c|M.abscessus_ATCC_199 GHDPHDHMNHDVPDDQLKSRLIGSLILAIPVVVIS----MAMPLHFSGWE Mb0106c|M.bovis_AF2122/97 DGAH---------ARRLLRRLLVAAVLFVPLADLSTLFAIVPSARVPGWG Rv0103c|M.tuberculosis_H37Rv DGAH---------ARRLLRRLLVAAVLFVPLADLSTLFAIVPSARVPGWG MMAR_0269|M.marinum_M DAEH---------ARTLLRRLLVAAVLFVPLADLSTMFALVPSTRFPGWG MUL_4845|M.ulcerans_Agy99 DAEH---------ARTLLRRLLVAAVLFVPLADLSTMFALVPSTRFPGWG MLBr_02000|M.leprae_Br4923 DADY---------ARNLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGWG ** . * *: :: : . :. * TH_4361|M.thermoresistible__bu WLALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLW Mvan_3670|M.vanbaalenii_PYR-1 WLALTLASPVVVWGALPFHRAAWANARHRAATMDTLISLGVSAAYLWSLW Mflv_2244|M.gilvum_PYR-GCK WLSLTLAAPVVVWGAWPFHRATWANLRHGTATMDTLISVGTLAAFGWSIY MSMEG_5014|M.smegmatis_MC2_155 WLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLY MAV_5246|M.avium_104 WAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLY MAB_3984c|M.abscessus_ATCC_199 ILVAALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLW Mb0106c|M.bovis_AF2122/97 YILTALAAPVVTWAAWPFHSVALRNARHRTTSMETLISVGIVAATAWSLS Rv0103c|M.tuberculosis_H37Rv YILTALAAPVVTWAAWPFHSVALRNARHRTTSMETLISVGIVAATAWSLS MMAR_0269|M.marinum_M YLLTALAAPIVTWAAWPFHSVAIRNARHRTASMETLISVGITAATVWSLS MUL_4845|M.ulcerans_Agy99 YLLTALAAPIVIWAAWPFHSVAIRNARHRTASMETLISVGITAATVWSLS MLBr_02000|M.leprae_Br4923 YLLTALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLS :*::*:: * . *** .: * :: .::*:**:* * ** **: TH_4361|M.thermoresistible__bu ALFFTAAGMPGMTMTFTLLP-ADTGEP------HIYLEVAAAVTTFIIAG Mvan_3670|M.vanbaalenii_PYR-1 ALFIGHAGMPGMRMAFSLLPDAGSETE------HIYLEVAAAVTVFILAG Mflv_2244|M.gilvum_PYR-GCK ALFWGTAGVPGMTHPFELTIARTDGSG------NIYLEAAAGVTTFILAG MSMEG_5014|M.smegmatis_MC2_155 ALFWGTAGVPGMTHPFSLVGSRTDGAG------NIYLEVAAGVTTFILAG MAV_5246|M.avium_104 ALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAG MAB_3984c|M.abscessus_ATCC_199 VLFANAGHTHGDVH--------------------VYFEVVAAVTVFLLAG Mb0106c|M.bovis_AF2122/97 SVFGDQPPREGSGIWRAILNSDS-----------IYLEVAAGVTVFVLAG Rv0103c|M.tuberculosis_H37Rv SVFGDQPPREGSGIWRAILNSDS-----------IYLEVAAGVTVFVLAG MMAR_0269|M.marinum_M TVFVDRQPRHSRGIWQAILNSDS-----------IYLEVAAGVTVFVLAG MUL_4845|M.ulcerans_Agy99 TVFVDRQPRQSRGIWQAILNSDS-----------IYLEVAAGVTVFVLAG MLBr_02000|M.leprae_Br4923 TIFVDKEPRQTHGIWQAILHSDS-----------IYFEVAAGVTVFVLAG :. :*:*..*.** *::** TH_4361|M.thermoresistible__bu RYFEARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPIGELHVGDVFV Mvan_3670|M.vanbaalenii_PYR-1 RYFEARAKTRSGAALRALLDMGAKDVAVVR-NGTEIRIPTAELSVGDVFV Mflv_2244|M.gilvum_PYR-GCK RYFEARAKRRAGAALRALLELGVRDVTVRR-GAAEHRIPIDQLRVDDEFV MSMEG_5014|M.smegmatis_MC2_155 RYFEAKSKRRASAALRALMELGAKDVAILR-NGAEQRIPIDQLGVGDEFV MAV_5246|M.avium_104 RYFERRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPIERLAVGDEFV MAB_3984c|M.abscessus_ATCC_199 RFAESRAKRSAGSALRALLSLGAKDVAVLR-GGHETRIPVDQLAVGDEFV Mb0106c|M.bovis_AF2122/97 RYFEARAKSKAGSALRALAELGAKNVAVLLPDGAELVIPASELKKRQRFV Rv0103c|M.tuberculosis_H37Rv RYFEARAKSKAGSALRALAELGAKNVAVLLPDGAELVIPASELKKRQRFV MMAR_0269|M.marinum_M RYFEARAKSKAGGALRALAALGAKDVTVLLPDGAELVIPAAELKKRQRFV MUL_4845|M.ulcerans_Agy99 RYFEARAKSKAGGALRALAALGAKDVTVLLPDGAELVIPAAELKKRQRFV MLBr_02000|M.leprae_Br4923 RFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFL *: * ::* :..***** *..:* : . * :* .* : *: TH_4361|M.thermoresistible__bu VRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGH Mvan_3670|M.vanbaalenii_PYR-1 VRPGEKIATDGVVTDGSSAVDASMLTGESVPVEVRPGDHVTGATVNAGGR Mflv_2244|M.gilvum_PYR-GCK VRPGEKVAADGIIVEGASAVDASMLTGESVPLEVKPGDRVVGATVNVDGR MSMEG_5014|M.smegmatis_MC2_155 VRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGR MAV_5246|M.avium_104 VRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGR MAB_3984c|M.abscessus_ATCC_199 VRPGERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGR Mb0106c|M.bovis_AF2122/97 TRPGETIAADGVVVDGSAAIDMSAMTGEAKPVRAYPAASVVGGTVVMDGR Rv0103c|M.tuberculosis_H37Rv TRPGETIAADGVVVDGSAAIDMSAMTGEAKPVRAYPAASVVGGTVVMDGR MMAR_0269|M.marinum_M TRPGQTIAADGVVIDGTAAIDMSAMTGESKPVRATADAPVIGGTIVLDGR MUL_4845|M.ulcerans_Agy99 TRPGQTIAADGVVIDGTAAIDMSAMTGESKPVRATADAPVIGGTIVLDGR MLBr_02000|M.leprae_Br4923 VRPGETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGR .***: :::** : * :::* : :***: *:.. * *. *: TH_4361|M.thermoresistible__bu LQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALS Mvan_3670|M.vanbaalenii_PYR-1 LLVRATRIGADTQLAQMARLVEDAQNGKASVQRLADRVSAVFVPIVLALS Mflv_2244|M.gilvum_PYR-GCK LVVRAERVGADTQLAQMARLVEDAQNGKAQAQRLADRISGVFVPVVLGLA MSMEG_5014|M.smegmatis_MC2_155 LVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALA MAV_5246|M.avium_104 LVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLA MAB_3984c|M.abscessus_ATCC_199 IVVRANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAIS Mb0106c|M.bovis_AF2122/97 LVIEATAVGADTQFAAMVRLVEQAQTQKARAQRLADHIAGVFVPVVFVIA Rv0103c|M.tuberculosis_H37Rv LVIEATAVGADTQFAAMVRLVEQAQTQKARAQRLADHIAGVFVPVVFVIA MMAR_0269|M.marinum_M LVIEATAVGADTQFAAMVRLVEEAQAQKARAQRLADRISAVFVPVVFAIA MUL_4845|M.ulcerans_Agy99 LVIEATAVGADTQFAAMVRLVEEAQAQKARAQRLADRISAVFVPVVFAIA MLBr_02000|M.leprae_Br4923 LVIEATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMVFVIA : :.* :* ***:* *.:** ** ** .*:***:::.****:*: :: TH_4361|M.thermoresistible__bu ALTLAGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA Mvan_3670|M.vanbaalenii_PYR-1 VATLAAWLLTGHS-ATVAFTAAVAVLIIACPCALGLATPTALMVGTGRGA Mflv_2244|M.gilvum_PYR-GCK VATLGFWIGSGYP-VAAAFTAAVAVLIIACPCALGLATPMALMVGTGRGA MSMEG_5014|M.smegmatis_MC2_155 VATLGFWLGTGGS-VAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA MAV_5246|M.avium_104 VATLAGWLAAGGT-LATALTAAVAVLIIACPCALGLATPTALLVGTGRAA MAB_3984c|M.abscessus_ATCC_199 ALTFVAWAALGNS-LASAFTAAVAVLIIACPCALGLATPTAILVGTGRGA Mb0106c|M.bovis_AF2122/97 GLAGAAWLVSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA Rv0103c|M.tuberculosis_H37Rv GLAGAAWLVSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA MMAR_0269|M.marinum_M GLAGAAWLLSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA MUL_4845|M.ulcerans_Agy99 GVAGVAWMLSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA MLBr_02000|M.leprae_Br4923 GLAGASWLLAGAS-PDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGA : * *::..:.**:*****:****** *::*.:**.* TH_4361|M.thermoresistible__bu QLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL----S Mvan_3670|M.vanbaalenii_PYR-1 QLGILIKGPQVLESTRRVDTIVLDKTGTVTTGRMSLVGVHPGAGQ----N Mflv_2244|M.gilvum_PYR-GCK QLGILIKGPEVLESTRRVDTVIVDKTGTVTTGDMTLVDVFAADGE----Q MSMEG_5014|M.smegmatis_MC2_155 QLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE----D MAV_5246|M.avium_104 QLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT----D MAB_3984c|M.abscessus_ATCC_199 QLGVLIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGV-AD Mb0106c|M.bovis_AF2122/97 QLGIFIKGYRALETIRSIDTVVFDKTGTLTVGQLAVSTVTMAGSGTSERD Rv0103c|M.tuberculosis_H37Rv QLGIFIKGYRALETIRSIDTVVFDKTGTLTVGQLAVSTVTMAGSGTSERD MMAR_0269|M.marinum_M QLGIFIKGYQALETIHGIDAVVFDKTGTLTVGKLTVNTVTTTGG----RV MUL_4845|M.ulcerans_Agy99 QLGIFIKGYQALETIHGIDAVVFEKTGTLTVGKLTVNTVTTTGG----RV MLBr_02000|M.leprae_Br4923 QLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGG----WC ***::*** ..**. . :*:::.:****:* * ::: * . TH_4361|M.thermoresistible__bu ETELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSG Mvan_3670|M.vanbaalenii_PYR-1 SDELLEFAGALESASQHPIAEAIAASAAAGG-TLPAVEDFSNHNGYGVTG Mflv_2244|M.gilvum_PYR-GCK PDEVLRMAGAVESPSEHPIAAAIAGGARDKLGDLPAVDGFANLRGLGVEG MSMEG_5014|M.smegmatis_MC2_155 RDDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQG MAV_5246|M.avium_104 RATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHG MAB_3984c|M.abscessus_ATCC_199 ADEILRIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSG Mb0106c|M.bovis_AF2122/97 REEVLGLAAAVESASEHAMAAAIVAASPDPG----PVNGFVAVAGCGVSG Rv0103c|M.tuberculosis_H37Rv REEVLGLAAAVESASEHAMAAAIVAASPDPG----PVNGFVAVAGCGVSG MMAR_0269|M.marinum_M REEVLALASAVEAASEHAVATAIVAASPHPA----PVTDFVAVAGCGVSG MUL_4845|M.ulcerans_Agy99 REEVLALASAVEAASEHAVATAIVAASPHPA----PVTDFVAVAGCGVSR MLBr_02000|M.leprae_Br4923 SGEVLALASAVEAASEHSVATAIVAAYADPR----PVADFVAFAGCGVSG :* *.::* .*:*.:* *:. .* * ** TH_4361|M.thermoresistible__bu RVDGHDVRVGRLAWLG----LSAGDRLRNAAAQAEAAGHTPVWVAVDGRI Mvan_3670|M.vanbaalenii_PYR-1 VVAGHAVLVGRLSWLTDDWSLTAPDDLTSAAEHAQSQGHTPVWVAWDGAV Mflv_2244|M.gilvum_PYR-GCK DVEGRRLTLGRLRLLSDR-SFEIPDDLASAVARAEAGGSTAVTVGWDGRA MSMEG_5014|M.smegmatis_MC2_155 TVEGRAVVVGRPRLFGDP-EKSLPRKLADAMEAAQAQGRTAVVVGWDGTA MAV_5246|M.avium_104 RVDGHAVAIGRPSWLAER-GLRPDAALAAAAARAEHDGKTVVAVGWDGRA MAB_3984c|M.abscessus_ATCC_199 VVDGQEVSI-----------------------EAIEGQNTTAAVSWGGLR Mb0106c|M.bovis_AF2122/97 EVGGHHVEVGKPSWIT-RTTPCHDAALVSARLDGESRGETVVFVSVDGVV Rv0103c|M.tuberculosis_H37Rv EVGGHHVEVGKPSWIT-RTTPCHDAALVSARLDGESRGETVVFVSVDGVV MMAR_0269|M.marinum_M IVDGHRIEVGKPSWIT-RNT-AADEVLDTARAQGESRGETIVFVSVDGEV MUL_4845|M.ulcerans_Agy99 IVDGHRIEVGKPSWIT-RNT-AADEVLDTARAQGESRGETIVFVSVDGEV MLBr_02000|M.leprae_Br4923 VVAEHHVKIGKPSWVT-RNA-PCDVVLESARREGESRGETVVFVSVDGVA * : : : . * . *. .* TH_4361|M.thermoresistible__bu AGVIVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID- Mvan_3670|M.vanbaalenii_PYR-1 RGVIVVADTVKGTSADAIGQFRKLGLRPFLLTGDNRRAALAVAAEVGIDP Mflv_2244|M.gilvum_PYR-GCK RGVLMVADAVKPTSAEAISLLKRAGLTPIMVTGDNEAVARTVAAQVGID- MSMEG_5014|M.smegmatis_MC2_155 RGVLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID- MAV_5246|M.avium_104 RGILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG- MAB_3984c|M.abscessus_ATCC_199 RGEIEVADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAA Mb0106c|M.bovis_AF2122/97 RAALTIADTLKDSAAAAVAALRSRGLRTILLTGDNRAAADAVAAQVGID- Rv0103c|M.tuberculosis_H37Rv RAALTIADTLKDSAAAAVAALRSRGLRTILLTGDNRAAADAVAAQVGID- MMAR_0269|M.marinum_M CAAVTISDTVKDSAADAIAALRSRGLRTILLTGDNQAAADSVATQLGID- MUL_4845|M.ulcerans_Agy99 CAAVTISDTVKDSAADAIAALRSRGLRTILLTGDNQAVADSVATQLGID- MLBr_02000|M.leprae_Br4923 CGAVAIADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGID- . : ::*::* : *: : * ..::**** .* * ::** TH_4361|M.thermoresistible__bu -DVIAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGT Mvan_3670|M.vanbaalenii_PYR-1 DDVIAEVLPADKVDTIKCLQAQGRTVAMVGDGVNDAAALVQADLGLAMGT Mflv_2244|M.gilvum_PYR-GCK -EVVAGVLPQDKVDTVTRLQRDGRVVAMVGDGVNDAAALAQADLGMAMGS MSMEG_5014|M.smegmatis_MC2_155 -DVYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGT MAV_5246|M.avium_104 -EVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGT MAB_3984c|M.abscessus_ATCC_199 GDVIAGVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGT Mb0106c|M.bovis_AF2122/97 -SAVADMLPEGKVDVIQRLREEGHTVAMVGDGINDGPALVGADLGLAIGR Rv0103c|M.tuberculosis_H37Rv -SAVADMLPEGKVDVIQRLREEGHTVAMVGDGINDGPALVGADLGLAIGR MMAR_0269|M.marinum_M -TAIADVLPDGKVNVIRQLRDQGHTVAMVGDGINDGPALVSADLGLAIGR MUL_4845|M.ulcerans_Agy99 -TAIADVLPDGKVNVIRQLRDQGHTVAMVGDGINDGPALVSADLGLAIGR MLBr_02000|M.leprae_Br4923 -TVIADMLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGLAMGR . : * *.: : *: *: ***:***:**..**. **:*:::* TH_4361|M.thermoresistible__bu GTDVAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAAL Mvan_3670|M.vanbaalenii_PYR-1 GSDVAIEASDLTLVRGDLRAAADAIRLARSTLRTIKGNLFWAFAYNVAAL Mflv_2244|M.gilvum_PYR-GCK GTDVAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKSNLFWAFAYNVAAL MSMEG_5014|M.smegmatis_MC2_155 GTDVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAAL MAV_5246|M.avium_104 GTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAI MAB_3984c|M.abscessus_ATCC_199 GTDAAIEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAI Mb0106c|M.bovis_AF2122/97 GTDVALGAADIILVRDDLNTVPQALDLARATMRTIRMNMIWAFGYNVAAI Rv0103c|M.tuberculosis_H37Rv GTDVALGAADIILVRDDLNTVPQALDLARATMRTIRMNMIWAFGYNVAAI MMAR_0269|M.marinum_M GTDVAIGAADIILVRDDLHIVGQALDLARATLRTIRTNMIWAFGYNVAAI MUL_4845|M.ulcerans_Agy99 GTDVAIGAADIILVRDDLHIVGQALDLARATMRTIRTNMIWAFGYNVAAI MLBr_02000|M.leprae_Br4923 GTDVAIGAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAI *:*.*: *.*: :* ..* . *: *.* *: **: *:.***.** **: TH_4361|M.thermoresistible__bu PLAAAGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR------------ Mvan_3670|M.vanbaalenii_PYR-1 PLAALGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTSSASPGQTEDVHVAT Mflv_2244|M.gilvum_PYR-GCK PLAAAGLLNPMIAGAAMAFSSVFVVTNSLRLRAFTPSR------------ MSMEG_5014|M.smegmatis_MC2_155 PLAAAGLLNPMLAGAAMAFSSVFVVSNSLRLKRFR--------------- MAV_5246|M.avium_104 PLAALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA--------- MAB_3984c|M.abscessus_ATCC_199 PLAALGLLNPMIAGAAMAMSSVFVVLNSLRLRTFR--------------- Mb0106c|M.bovis_AF2122/97 PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGAQ------------- Rv0103c|M.tuberculosis_H37Rv PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGAQ------------- MMAR_0269|M.marinum_M PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGPPTARIVASNGEIDD MUL_4845|M.ulcerans_Agy99 PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGPPTARIVASNGEIDD MLBr_02000|M.leprae_Br4923 PIASSGLLNPLIAGAAMAFSSFFVVSNSLRLSNFGLSQTSD--------- *:*: *:***::******:**.:** ***** * TH_4361|M.thermoresistible__bu --------------- Mvan_3670|M.vanbaalenii_PYR-1 VPPGGDEYRRAHTAP Mflv_2244|M.gilvum_PYR-GCK --------------- MSMEG_5014|M.smegmatis_MC2_155 --------------- MAV_5246|M.avium_104 --------------- MAB_3984c|M.abscessus_ATCC_199 --------------- Mb0106c|M.bovis_AF2122/97 --------------- Rv0103c|M.tuberculosis_H37Rv --------------- MMAR_0269|M.marinum_M --------------- MUL_4845|M.ulcerans_Agy99 --------------- MLBr_02000|M.leprae_Br4923 ---------------