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AETTVLDVRGLHWASSEAIIESTLRRRPGVVAVNANAANQTATVTFDPAQTTLAQLTEWIRDCGFHCQGR AVPDHICEPIPMPDAAPSPHDMMGHGGHGAMSMDAMVRDMRNRFLVALLLSIPIMLWSPMGRDMFGFGVP APFGLRDDVFALILSLPVVFYSAWIFFDGAYRALRARTLDMMVLVAVAVGAGWLYSVGVTLTGGGEVFYE AASVLTTFVLLGHWFEMRARGGANDAIRALLELAPPLAVVLRDGEPVEVPTAEVATGDLLLIRPGAKIPV DGTVEQGHSEVDESMVTGESLPVAKDPGSTVIGASINTTGTLRVRATKVGSDTALAQIVQMVQEAQNSKA PGQRLADRAAFWLVLVALLGGTATFLVWWAVGAGVQSALLFAITVVVITCPDALGLATPTAIMVGTGLGA KRGVLFKNATALEISARIDTVVMDKTGTLTKGEPEVTDVVVEGISEEEFLALVAAVETESEHPLAAAIVR YAAERGVTPLPLSAFQNVPGQGATAEVDGRQVAVGNRKLMVDRRVDFGELMDRRDELAASGRTAVLVTVD GRGVGVIALADAARETSAAAVTALHDLGVEVVMLSGDNEATAKRIAAQLGIDTVIAEVLPGDKAANIAAL QRDGRKVAMVGDGVNDAPALAQADLGVAIGAGTDVAIETADLVLMRSDPLDVPIALRIGRGTLRKMRQNL AWAVGYNVIALPIAAGVFQPAFGLVLRPEIAALSMSGSSFIVAVNALTLKRLKLPGTPAGDERPGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5853 | - | - | 100% (767) | heavy metal translocating P-type ATPase |
| M. vanbaalenii PYR-1 | Mvan_3678 | - | 0.0 | 82.07% (792) | copper-translocating P-type ATPase |
| M. vanbaalenii PYR-1 | Mvan_4449 | - | e-143 | 41.04% (770) | heavy metal translocating P-type ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0994 | ctpV | 1e-144 | 46.48% (654) | metal cation transporter P-type ATPase CtpV |
| M. gilvum PYR-GCK | Mflv_3886 | - | 1e-141 | 44.54% (669) | copper-translocating P-type ATPase |
| M. tuberculosis H37Rv | Rv0969 | ctpV | 1e-144 | 46.48% (654) | metal cation transporter P-type ATPase CtpV |
| M. leprae Br4923 | MLBr_02000 | ctpB | 1e-117 | 38.05% (770) | cation-transporting ATPase |
| M. abscessus ATCC 19977 | MAB_0449 | - | 1e-129 | 43.25% (652) | copper-transporting ATPase |
| M. marinum M | MMAR_1448 | - | 1e-159 | 46.94% (671) | zinc cation transport ATPase |
| M. avium 104 | MAV_5246 | - | 1e-122 | 38.19% (775) | copper-translocating P-type ATPase |
| M. smegmatis MC2 155 | MSMEG_5014 | - | 1e-139 | 40.52% (770) | copper-translocating P-type ATPase |
| M. thermoresistible (build 8) | TH_4361 | - | 1e-144 | 42.67% (771) | PUTATIVE heavy metal translocating P-type ATPase |
| M. ulcerans Agy99 | MUL_0423 | ctpV | 1e-144 | 47.93% (603) | metal cation transporter p-type ATPase, CtpV |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0994|M.bovis_AF2122/97 ----------------MRVCVTGFNVDAVRAVAIEETVSQVTGVHAV---
Rv0969|M.tuberculosis_H37Rv ----------------MRVCVTGFNVDAVRAVAIEETVSQVTGVHAV---
MUL_0423|M.ulcerans_Agy99 ----------------MRVHANGFAIDATRAAAIEESVGRVGGVRAV---
MAV_5246|M.avium_104 ------------------MSTPPRHIDEGTFPDHTASTARIELEITG---
MSMEG_5014|M.smegmatis_MC2_155 ---------------------------------MTTATGHVELQIGG---
TH_4361|M.thermoresistible__bu --------------------------------MNTGGMNTVTLTVGG---
MLBr_02000|M.leprae_Br4923 -------------------MTASLVEDTN---NNHESVRRIQLDVAG---
MMAR_1448|M.marinum_M MSSVDVIVPVGAALVIAGLAWYFFAPRRAHAASLSEGVQRILVTIRGGYS
Mflv_3886|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0449|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_5853|M.vanbaalenii_PYR-1 -----------------MAETTVLDVRGLHWASSEAIIESTLRRRPG---
Mb0994|M.bovis_AF2122/97 ----HAYPRTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSA
Rv0969|M.tuberculosis_H37Rv ----HAYPRTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSA
MUL_0423|M.ulcerans_Agy99 ----RAYPRTASVVIWYSPAHCDTAAIVSAIAEAEHAGDASAPAPAARVA
MAV_5246|M.avium_104 ----MTCASCAARIEKKLNKLDGVTATVNYATEKAAVSAPASYDPQTLIT
MSMEG_5014|M.smegmatis_MC2_155 ----MTCASCAARIERKLNKLDGVTASVNYATEKASVEVAGEVSPETLIE
TH_4361|M.thermoresistible__bu ----MTCASCAARVEKRLNRIDGVVATVNFATEQATVRYPDHVDPADLIA
MLBr_02000|M.leprae_Br4923 ----MLCAACASRVETKLNKIPGVRASVNFATRVATIDAVD-VAVDELRQ
MMAR_1448|M.marinum_M PNVVQVRQGAPVEIEFDRQESGDCSSRVVFPDLHLSAALPAHQRTTVRFT
Mflv_3886|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0449|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_5853|M.vanbaalenii_PYR-1 ----VVAVNANAANQTATVTFDPAQTTLAQLTEWIRDCGFHCQGRAVPDH
Mb0994|M.bovis_AF2122/97 GVRGVGVVRKITGGIRRMLS----------------RPPGVDKPLKASRC
Rv0969|M.tuberculosis_H37Rv GVRGVGVVRKITGGIRRMLS----------------RPPGVDKPLKASRC
MUL_0423|M.ulcerans_Agy99 GIADGGVVGRVIGGLARALLGMRTDDNDD------DPPPEIARLRAALDR
MAV_5246|M.avium_104 EIENAGYAAAVATP------------------------------------
MSMEG_5014|M.smegmatis_MC2_155 VVETAGYTAHLPAP------------------------------------
TH_4361|M.thermoresistible__bu AIEATGYTASLPAPQRDTGG------------------------------
MLBr_02000|M.leprae_Br4923 VIEQAGYRATAHAE------------------------------------
MMAR_1448|M.marinum_M PQQAGSFGFFCSMNMINGTLVVTPDGQAAGSAEPEQPNASIGYAATNSGD
Mflv_3886|M.gilvum_PYR-GCK ----------MTGN------------------------------------
MAB_0449|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_5853|M.vanbaalenii_PYR-1 ICEPIPMPDAAPSP------------------------------------
Mb0994|M.bovis_AF2122/97 GGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLG---LLALG-SSMF
Rv0969|M.tuberculosis_H37Rv GGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLG---LLALG-SSMF
MUL_0423|M.ulcerans_Agy99 IGYSPEQDTATQLSPSEQARSGIRFWSRRAWLAWPLG---LLASG-LTMF
MAV_5246|M.avium_104 --SPPRD-----DPE---LASLRRRLVTAIALAGPVI---AVA----MIP
MSMEG_5014|M.smegmatis_MC2_155 --PQPETGGTEQDPEDRATDALRTRLLVSAVLTVPVI---AMA----MVP
TH_4361|M.thermoresistible__bu -APAGAATGAAGDDHDAEAERWRRRLTISAALSIPVV---VLS----MIP
MLBr_02000|M.leprae_Br4923 ------SAVEEIDPDADYARNLLRRLIVAALLFVPLA---DLSTMFAIVP
MMAR_1448|M.marinum_M EPAAAEIEAAQAQERRAEITDLSRRVAFGAVLSAPVLYA-VMAQPLGAGW
Mflv_3886|M.gilvum_PYR-GCK -HDHHGHAGHGDH-----AAQFRKLFWLNLILAVPVVAFSGMFAMLVGYD
MAB_0449|M.abscessus_ATCC_1997 ----------------------------MLVVAVPVVVFDPMFAMLLGYQ
Mvan_5853|M.vanbaalenii_PYR-1 -HDMMGHGGHGAMSMDAMVRDMRNRFLVALLLSIPIMLWSPMGRDMFGFG
: *: :
Mb0994|M.bovis_AF2122/97 FGAYPWAG--WLAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALG
Rv0969|M.tuberculosis_H37Rv FGAYPWAG--WLAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALG
MUL_0423|M.ulcerans_Agy99 FGAYPWAG--WLAFAATIPVQFIAGWPFLVGAVQQARARSANMNTLISLG
MAV_5246|M.avium_104 ALQFQHWH--WAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIG
MSMEG_5014|M.smegmatis_MC2_155 ALQFTNWQ--WLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMG
TH_4361|M.thermoresistible__bu ALQFTHWQ--WLALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLG
MLBr_02000|M.leprae_Br4923 TNRFPGWG--YLLTALAAPIVTWAAWPFHRVALRNARYRAASMETLISAG
MMAR_1448|M.marinum_M VPAVLLHH--WLQLALITPVMFYVGWPIHRTGWLALAHRSADMNSLITLG
Mflv_3886|M.gilvum_PYR-GCK VPDVPGAR--WVAPLLGTVMYVVGGRPFLSGALDEIRSRKPAMMLLIGLA
MAB_0449|M.abscessus_ATCC_1997 LPDAGWAR--WVFPVLGTVVYLWGGKPFLVGAVSEIRSRTPGMMLLIGLA
Mvan_5853|M.vanbaalenii_PYR-1 VPAPFGLRDDVFALILSLPVVFYSAWIFFDGAYRALRARTLDMMVLVAVA
: . : . * *: .
Mb0994|M.bovis_AF2122/97 TLTAFVYSTYQLFAGGP---------------------------LFFDTS
Rv0969|M.tuberculosis_H37Rv TLTAFVYSTYQLFAGGP---------------------------LFFDTS
MUL_0423|M.ulcerans_Agy99 TLTAFIYSTYQLFAGGP---------------------------LFFDTA
MAV_5246|M.avium_104 TLAAFLWSLYALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVA
MSMEG_5014|M.smegmatis_MC2_155 TLAAFGWSLYALFWGTAGVPGMTHPFSLVG------SRTDGAGNIYLEVA
TH_4361|M.thermoresistible__bu VTAAYLWSLWALFFTAAGMPGMTMTFTLLP-------ADTGEPHIYLEVA
MLBr_02000|M.leprae_Br4923 ILAATGWSLSTIFVDKE--PRQTHGIWQAI---------LHSDSIYFEVA
MMAR_1448|M.marinum_M TFAAYGYSLLVTAASTALP--------------------AELQDVYYEAV
Mflv_3886|M.gilvum_PYR-GCK ITVAFVASWGASLGLLHHEL------------------------EFWWEL
MAB_0449|M.abscessus_ATCC_1997 ITVAFTASWGASIGVLDHQL------------------------SFWWEL
Mvan_5853|M.vanbaalenii_PYR-1 VGAGWLYSVGVTL--TGGGE------------------------VFYEAA
.. * :
Mb0994|M.bovis_AF2122/97 ALIIAFVVLGRHLEARATGKASEAISKLLELGAKEATLLV-DGQELLVPV
Rv0969|M.tuberculosis_H37Rv ALIIAFVVLGRHLEARATGKASEAISKLLELGAKEATLLV-DGQELLVPV
MUL_0423|M.ulcerans_Agy99 ALIIAFVVLGRYFEATAHGKTREAISKLLDMGAKETRLIV-DGEEHLVPV
MAV_5246|M.avium_104 AGVTLFVLAGRYFERRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPI
MSMEG_5014|M.smegmatis_MC2_155 AGVTTFILAGRYFEAKSKRRASAALRALMELGAKDVAILR-NGAEQRIPI
TH_4361|M.thermoresistible__bu AAVTTFIIAGRYFEARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPI
MLBr_02000|M.leprae_Br4923 AGVTVFVLAGRFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPA
MMAR_1448|M.marinum_M GVILTLIMLGRLLEARAKAGTGEAIRALLGLQARTARVIR-NGTQAEIPV
Mflv_3886|M.gilvum_PYR-GCK ALLIVIMLLGHWVEMRSLAQTTSALDSLAALLPDEAEKVD-GDRTITVAP
MAB_0449|M.abscessus_ATCC_1997 ALLVVIMLAGHWIEMRSLAQTTSALDSLAALLPDTAERVQ-GQQVVTVPL
Mvan_5853|M.vanbaalenii_PYR-1 SVLTTFVLLGHWFEMRARGGANDAIRALLELAPPLAVVLR-DGEPVEVPT
. : ::: *: .* : : *: * . . : :.
Mb0994|M.bovis_AF2122/97 DQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRV
Rv0969|M.tuberculosis_H37Rv DQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRV
MUL_0423|M.ulcerans_Agy99 DRVQVGDLVRVRPGEKIPVDGEVIDGRAAVDESMLTGESVPVEKGVGDWV
MAV_5246|M.avium_104 ERLAVGDEFVVRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGV
MSMEG_5014|M.smegmatis_MC2_155 DQLGVGDEFVVRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQV
TH_4361|M.thermoresistible__bu GELHVGDVFVVRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQV
MLBr_02000|M.leprae_Br4923 GELKKQQHFLVRPGETITADGVVIDGTATIDMSAITGEARPVHASPASTV
MMAR_1448|M.marinum_M DEVVVGDDILVRPGEKIAVDATVVSGQSTVDESMVTGESMPVTKHTGDTV
Mflv_3886|M.gilvum_PYR-GCK ADLRVGDVVVVRPGGSIPADGRIIDGRAEVDESMITGESRPVGRGVGDAV
MAB_0449|M.abscessus_ATCC_1997 ADLRVGDIVVVRPGGSVPADGRVVEGSASLDESMVTGESAPVRRGVGEQV
Mvan_5853|M.vanbaalenii_PYR-1 AEVATGDLLLIRPGAKIPVDGTVEQGHSEVDESMVTGESLPVAKDPGSTV
: : . :*** :..*. : * : :* : :***: ** .. *
Mb0994|M.bovis_AF2122/97 AGATVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSA
Rv0969|M.tuberculosis_H37Rv AGATVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSA
MUL_0423|M.ulcerans_Agy99 AGATVNTDGLLTVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADRVSA
MAV_5246|M.avium_104 TGGTVNAGGRLVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSG
MSMEG_5014|M.smegmatis_MC2_155 VGATVNVGGRLVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSA
TH_4361|M.thermoresistible__bu VGATVNVGGHLQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSA
MLBr_02000|M.leprae_Br4923 VGGTTVLDGRLVIEATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAA
MMAR_1448|M.marinum_M IGATVNTTGSLRIRAAKVGADTMLAQIIGMVQQAQASRAPIQRLADAISA
Mflv_3886|M.gilvum_PYR-GCK TAGTVATDSGLRVQVTAIGEDTALAGIRRLVTEAQNSSSRAQRLADRAAG
MAB_0449|M.abscessus_ATCC_1997 VAGTVATDSGLRVQVSAVGADTALAGIQRLVADAQASTSRAQRVADTAAG
Mvan_5853|M.vanbaalenii_PYR-1 IGASINTTGTLRVRATKVGSDTALAQIVQMVQEAQNSKAPGQRLADRAAF
..: . * :.. :* ** :* : :* ** : *::** :
Mb0994|M.bovis_AF2122/97 VFVPAVIGVAVATFAGWTL--IAANPVAGMTAAVAVLIIACPCALGLATP
Rv0969|M.tuberculosis_H37Rv VFVPAVIGVAVATFAGWTL--IAANPVAGMTAAVAVLIIACPCALGLATP
MUL_0423|M.ulcerans_Agy99 VFVPVVVRIAAATFAGWTL--LAANPVAGMTAAVSVLIIACPYALGLATP
MAV_5246|M.avium_104 VFVPVVLLLAVATLAGWLA--AGGTLATALTAAVAVLIIACPCALGLATP
MSMEG_5014|M.smegmatis_MC2_155 VFVPIVIALAVATLGFWLG--TGGSVAAAFTAAVAVLIIACPCALGLATP
TH_4361|M.thermoresistible__bu VFVPIVIALSALTLAGWLLL-TDAPVSAAFTAAVAVLIIACPCALGLATP
MLBr_02000|M.leprae_Br4923 VFVPMVFVIAGLAGASWLL--AGASPDRAFSVVLGVLVIACPCTLGLATP
MMAR_1448|M.marinum_M YFVPVVIAIAIATFAVWFVAGPTPELTQALVSAVAVLIIACPCALGLATP
Mflv_3886|M.gilvum_PYR-GCK WLFWFALVTALVTAAAWSA--IGD-VDAAVIRAITVLVIACPHALGLAIP
MAB_0449|M.abscessus_ATCC_1997 WLFWFALAAAIITAVTWTA--LGH-PDAAVVRAITVLVIACPHALGLAIP
Mvan_5853|M.vanbaalenii_PYR-1 WLVLVALLGGTATFLVWWA--VGAGVQSALLFAITVVVITCPDALGLATP
:. .. . : * .. .: *::*:** :**** *
Mb0994|M.bovis_AF2122/97 TAIMVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDV
Rv0969|M.tuberculosis_H37Rv TAIMVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDV
MUL_0423|M.ulcerans_Agy99 TAIIVGTGRGADMGILVKGGEVLEASKKIDTVVFDKTGTLTRAQMELTDV
MAV_5246|M.avium_104 TALLVGTGRAAQLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDV
MSMEG_5014|M.smegmatis_MC2_155 TALLVGTGRGAQLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDV
TH_4361|M.thermoresistible__bu TALLVGTGRGAQLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSV
MLBr_02000|M.leprae_Br4923 TAMMVASGRGAQLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTV
MMAR_1448|M.marinum_M LSIMVGTGKGARAGILIRSAEALETAHKLDTIVLDKTGTVTAGRPALTDV
Mflv_3886|M.gilvum_PYR-GCK LVISIATERAARGGVLIKDRLALEGMRTVDAVLFDKTGTLTRGEPTVTAV
MAB_0449|M.abscessus_ATCC_1997 LVVSIATERAARGGVLVKDRLALEQMRTVDVVLFDKTGTLTKGTPTLTGI
Mvan_5853|M.vanbaalenii_PYR-1 TAIMVGTGLGAKRGVLFKNATALEISARIDTVVMDKTGTLTKGEPEVTDV
: :.: .* *::.:. .** :*.:::*****:* . : :
Mb0994|M.bovis_AF2122/97 IAGQRRQPNQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAV
Rv0969|M.tuberculosis_H37Rv IAGQRRQPDQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAV
MUL_0423|M.ulcerans_Agy99 IAGKRRQPDVVLRIAAAVESGSEHPIGAAIVAGARERELEVPPATEFTNL
MAV_5246|M.avium_104 VAADGTDRATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAV
MSMEG_5014|M.smegmatis_MC2_155 VVADGEDRDDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANI
TH_4361|M.thermoresistible__bu HVADGLSETELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENH
MLBr_02000|M.leprae_Br4923 TSTGGWCSGEVLALASAVEAASEHSVATAIVAAYADPR----PVADFVAF
MMAR_1448|M.marinum_M EVTGTLQQNELLALVAAAEANSEHPVATAVLAGSRDRGIDHSAADDFASI
Mflv_3886|M.gilvum_PYR-GCK DAVAGLGSDTVLALAAAAEADSEHPLARAIVRAAQKRRITVPTAAGFTSS
MAB_0449|M.abscessus_ATCC_1997 EAAPGHDGDAVLALAAAAETDSEHPLARAIVAAARQRGLDIPAASGFTSE
Mvan_5853|M.vanbaalenii_PYR-1 -VVEGISEEEFLALVAAVETESEHPLAAAIVRYAAERGVTPLPLSAFQNV
.* ..* * ***.:. *: *
Mb0994|M.bovis_AF2122/97 AGHGVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFV
Rv0969|M.tuberculosis_H37Rv AGHGVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFV
MUL_0423|M.ulcerans_Agy99 AGHGVRGEVGGKSVLVGRRKLVDEQHLRLPEQLAAAAADLEERGRTAVYV
MAV_5246|M.avium_104 GGGGVHGRVDGHAVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAV
MSMEG_5014|M.smegmatis_MC2_155 EGLGVQGTVEGRAVVVGRPRLFGDPEKSLPRKLADAMEAAQAQGRTAVVV
TH_4361|M.thermoresistible__bu GGNGVSGRVDGHDVRVGRLAWLG---LSAGDRLRNAAAQAEAAGHTPVWV
MLBr_02000|M.leprae_Br4923 AGCGVSGVVAEHHVKIGKPSWVTRN-APCDVVLESARREGESRGETVVFV
MMAR_1448|M.marinum_M TGKGVRATVAGRTVLVGTATLLAEN-NVTTSELERIGADLAAKGKTPILA
Mflv_3886|M.gilvum_PYR-GCK PAVGVAATVEGHDIRVGGPRLLQEVDADE---VAEAD-RWRAEGAIILHV
MAB_0449|M.abscessus_ATCC_1997 PALGVSAQVAETRVQVGGPALLDARGSRE---LAVAA-QWRTEGAIILHV
Mvan_5853|M.vanbaalenii_PYR-1 PGQGATAEVDGRQVAVGNRKLMVDRRVDFGELMDRRD-ELAASGRTAVLV
. *. . * : :* . : * : .
Mb0994|M.bovis_AF2122/97 GQDGQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAK
Rv0969|M.tuberculosis_H37Rv GQDGQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAK
MUL_0423|M.ulcerans_Agy99 GQDGQVVGVLAVADTVKDDAADVVSQLHAMGLQVALITGDNARTAAAIAA
MAV_5246|M.avium_104 GWDGRARGILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAG
MSMEG_5014|M.smegmatis_MC2_155 GWDGTARGVLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIAD
TH_4361|M.thermoresistible__bu AVDGRIAGVIVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAA
MLBr_02000|M.leprae_Br4923 SVDGVACGAVAIADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAA
MMAR_1448|M.marinum_M AVDGRPAGVLAVADTVKDDSMAAIAALGKLGLQVVMITGDNARTAKAIAR
Mflv_3886|M.gilvum_PYR-GCK VRDGAVVGGLRLADEIRPESRDAVDALHTLGVEVVMITGDAEAVAMSVGR
MAB_0449|M.abscessus_ATCC_1997 LLDGQVAAALRLADDIRPESADTVKALHKLGVRVVMITGDAQAVADTVAG
Mvan_5853|M.vanbaalenii_PYR-1 TVDGRGVGVIALADAARETSAAAVTALHDLGVEVVMLSGDNEATAKRIAA
** . : ::* : : .: : * :::** .* .
Mb0994|M.bovis_AF2122/97 QVGIEKVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADLGI
Rv0969|M.tuberculosis_H37Rv QVGIEKVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADLGI
MUL_0423|M.ulcerans_Agy99 QVGIDRVLAEVLPADKVNEVRRLQDEGRIVAMVGDGVNDAPALVQADLGI
MAV_5246|M.avium_104 ELGIGEVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGL
MSMEG_5014|M.smegmatis_MC2_155 QVGIDDVYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGL
TH_4361|M.thermoresistible__bu QVGIDDVIAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGL
MLBr_02000|M.leprae_Br4923 QVGIDTVIADMLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGL
MMAR_1448|M.marinum_M QVGVSRVLAEVLPEHKAGEIRRLQAEGRTVGMVGDGINDAPALAQADVGL
Mflv_3886|M.gilvum_PYR-GCK ELGIDRVFAGVRPEDKATKVAALQHEGKKVAMVGDGVNDAPALAQADVGI
MAB_0449|M.abscessus_ATCC_1997 RLGVDRVFAQVRPQDKAAAVAQLQQEGHTVAMVGDGVNDAPALAQADVGI
Mvan_5853|M.vanbaalenii_PYR-1 QLGIDTVIAEVLPGDKAANIAALQRDGRKVAMVGDGVNDAPALAQADLGV
.:*: * : * *. : *: *: *.*:***:**..**. **:*:
Mb0994|M.bovis_AF2122/97 AIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYN
Rv0969|M.tuberculosis_H37Rv AIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYN
MUL_0423|M.ulcerans_Agy99 AIGTGTDVAIEASDITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAFGYN
MAV_5246|M.avium_104 AMGTGTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYN
MSMEG_5014|M.smegmatis_MC2_155 SMGTGTDVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYN
TH_4361|M.thermoresistible__bu AIGTGTDVAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYN
MLBr_02000|M.leprae_Br4923 AMGRGTDVAIGAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYN
MMAR_1448|M.marinum_M AIGTGTDVAIEAADITLISGSLAGVVTAIQLSRATMRNIRENLFFALIYN
Mflv_3886|M.gilvum_PYR-GCK AIGAGTDVAIASAGVILASSDPRSVLSVIELSRATYRKMKQNLWWGAGYN
MAB_0449|M.abscessus_ATCC_1997 AIGAGTDVAIASAGVILASSDPRSVLSVIELSRASYRKMKQNLWWAAGYN
Mvan_5853|M.vanbaalenii_PYR-1 AIGAGTDVAIETADLVLMRSDPLDVPIALRIGRGTLRKMRQNLAWAVGYN
::* ****** :..: : . . .: :.* : .: *: :. **
Mb0994|M.bovis_AF2122/97 TAAIPLAA------LGA-LNPVVAGAAMGFSSVSVVTNSLRLRRFGRDGR
Rv0969|M.tuberculosis_H37Rv TAAIPLAA------LGA-LNPVVAGAAMGFSSVSVVTNSLRLRRFGRDGR
MUL_0423|M.ulcerans_Agy99 TAAIPLAA------LGV-LNPVVAGAAMGLSSVSVVTNSLRLRRFGRDV-
MAV_5246|M.avium_104 LAAIPLAA------LGM-LNPMLAGAAMALSSVLVVGNSLRLRSFASIIP
MSMEG_5014|M.smegmatis_MC2_155 VAALPLAA------AGL-LNPMLAGAAMAFSSVFVVSNSLRLKRFR----
TH_4361|M.thermoresistible__bu VAALPLAA------AGL-LNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR-
MLBr_02000|M.leprae_Br4923 VAAIPIAS------SGL-LNPLIAGAAMAFSSFFVVSNSLRLSNFGLSQT
MMAR_1448|M.marinum_M AIGIPLAAGVLYPTLGLRLSPMIAAAAMALSSLSVVGNANRLRRYRVEPL
Mflv_3886|M.gilvum_PYR-GCK LVSVPLAAGVLAP-VGFILPMSVGAVLMSLSTIVVALNAQLLRRLDLSPE
MAB_0449|M.abscessus_ATCC_1997 LISVPLAAGVAAP-IGFVMPMSAGAVLMSLSTVVVALNSQLLRRLDLRPQ
Mvan_5853|M.vanbaalenii_PYR-1 VIALPIAAGVFQPAFGLVLRPEIAALSMSGSSFIVAVNALTLKRLKLPGT
.:*:*: * : .. *. *:. *. *: *
Mb0994|M.bovis_AF2122/97 TA----------------------------------------
Rv0969|M.tuberculosis_H37Rv TA----------------------------------------
MUL_0423|M.ulcerans_Agy99 ------------------------------------------
MAV_5246|M.avium_104 GA----------------------------------------
MSMEG_5014|M.smegmatis_MC2_155 ------------------------------------------
TH_4361|M.thermoresistible__bu ------------------------------------------
MLBr_02000|M.leprae_Br4923 SD----------------------------------------
MMAR_1448|M.marinum_M PPAEAPTTEPRVETVTAQSESGDR------------------
Mflv_3886|M.gilvum_PYR-GCK AGTRAVLSGDGRGRRTAPAAPRQPRGTEGAEASAPRGRSRSS
MAB_0449|M.abscessus_ATCC_1997 TSARNMLNS---------------------------------
Mvan_5853|M.vanbaalenii_PYR-1 PAGDERPGR---------------------------------