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PETTGLPATLSNVELDIAGMTCASCAMRIEKKLNKLDGVSATVNYATERATVTAPAGYDPQILITEVKKA GYAAALPQHRQQPAAAAKTDTHGVDPELASLRGRLVGAVVLAGPVILMAMLPALQFRYWQWASLALAAPV IVWAGRPFHQAAWVNLKHGTATMDTLISVGTLAAFLWSLYALFLGTAGEPGMRHPFELTITPGDGASNIY LEVAAGVIAFVLAGRYFEKRSKRRAGAALQALLELGAKDVAVLRNGAEIRVPVQELTVDDEFVVRPGEKI ATDGTVVAGSSAVDASMLTGESVPVEVGPGDTVTGATTNAGGRLVVRATRVGEHTQLAQMAKLVEAAQSG KADVQRLADRVSGVFVPIVIAIAVTTLGVWLGAGYPVSAALTAAVAVLIIACPCALGLATPTALLVGTGR AAALGVLIKGPEMLESTRRVDTIVLDKTGTVTTGKMTLLEVITVPDTDRATALRYAGGLEAASEHPIAAA IVKSARAELGALPEPADFANTEGQGVRGIIDGHAVIVGRASLLADWAQHLDPDLAAAKDRAESQGKTAVA VGWDGRARAILVIADTVKPTSAAAIREFKRLGLTPVLLTGDNPTVARHIADEVGIDEVIADVLPAGKVAA VRRLQSEGKIVAMVGDGVNDAAALATADLGLAMGTGADVAIEAADLTLVRGDLRAAADAIRLSRRTLNTI KTNLFWAFGYNVAALPLAAFGLLNPMLAGAAMAFSSVFVVGNSLRLRSFTSVITDAPPATGSPTRWDATP ESPAELSTLPGEPSGCPR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0231 | ctpA_1 | - | 100% (789) | cation transporter p-type ATPase CtpA_1 |
M. marinum M | MMAR_0264 | ctpA | 0.0 | 47.63% (758) | cation transporter p-type ATPase a CtpA |
M. marinum M | MMAR_0269 | ctpB | 0.0 | 50.00% (746) | cation-transporter p-type ATPase B CtpB |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0095 | ctpA | 0.0 | 49.13% (749) | cation transporter P-type ATPase A |
M. gilvum PYR-GCK | Mflv_2849 | - | 0.0 | 74.87% (756) | heavy metal translocating P-type ATPase |
M. tuberculosis H37Rv | Rv0092 | ctpA | 0.0 | 49.13% (749) | cation transporter P-type ATPase A |
M. leprae Br4923 | MLBr_02000 | ctpB | 1e-175 | 47.42% (757) | cation-transporting ATPase |
M. abscessus ATCC 19977 | MAB_3984c | - | 0.0 | 54.06% (751) | putative metal transporter ATPase |
M. avium 104 | MAV_5246 | - | 0.0 | 72.72% (755) | copper-translocating P-type ATPase |
M. smegmatis MC2 155 | MSMEG_5014 | - | 0.0 | 70.19% (738) | copper-translocating P-type ATPase |
M. thermoresistible (build 8) | TH_4361 | - | 0.0 | 63.47% (750) | PUTATIVE heavy metal translocating P-type ATPase |
M. ulcerans Agy99 | MUL_4850 | ctpA | 0.0 | 47.80% (751) | cation transporter p-type ATPase a CtpA |
M. vanbaalenii PYR-1 | Mvan_4449 | - | 0.0 | 68.02% (741) | heavy metal translocating P-type ATPase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0231|M.marinum_M -------MPETTG--LPATLSNVELDIAGMTCASCAMRIEKKLNKLDGVS MAV_5246|M.avium_104 MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT Mflv_2849|M.gilvum_PYR-GCK ---------MTTS--IPVSGPSIELRIGGMTCASCANRIERKLNKIDGVA MSMEG_5014|M.smegmatis_MC2_155 ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT Mvan_4449|M.vanbaalenii_PYR-1 -------------------MNTIELSIGGMTCASCAARVEKKLNKLDGVT TH_4361|M.thermoresistible__bu --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV MAB_3984c|M.abscessus_ATCC_199 ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN Mb0095|M.bovis_AF2122/97 ---MTAAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR Rv0092|M.tuberculosis_H37Rv ---MTTAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR MUL_4850|M.ulcerans_Agy99 --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR MLBr_02000|M.leprae_Br4923 ---MTASLVEDTNNN-HESVRRIQLDVAGMLCAACASRVETKLNKIPGVR * : ** * :** ::: **:: ** MMAR_0231|M.marinum_M ATVNYATERATVTAPAGYDPQILITEVKKAGYAAALPQHRQQPAAAAKTD MAV_5246|M.avium_104 ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATP------SPPRD Mflv_2849|M.gilvum_PYR-GCK ATVNYATEKATVTVPDGYDPALLIAEVQNAGYSAALPTPEKPALTGETGE MSMEG_5014|M.smegmatis_MC2_155 ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAPPQPETGGTEQD Mvan_4449|M.vanbaalenii_PYR-1 ATVNFATEKARVAFGDEVSPGQLVSAVESAGYQAELPERPD-----EPAE TH_4361|M.thermoresistible__bu ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGA MAB_3984c|M.abscessus_ATCC_199 ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD Mb0095|M.bovis_AF2122/97 AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDPDAD Rv0092|M.tuberculosis_H37Rv AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDPDAD MUL_4850|M.ulcerans_Agy99 ASVNFGTRTAIVEAGEDVDAAALCEVIQQAGYQAEVQPDDGQGAGDSDAE MLBr_02000|M.leprae_Br4923 ASVNFATRVATIDA-VDVAVDELRQVIEQAGYRATAHAESAVEEIDPDAD * ** . . * : * :. .** * MMAR_0231|M.marinum_M THGV------DPELASLRGRLVGAVVLAGPVILMAMLPALQFRYWQWASL MAV_5246|M.avium_104 ----------DPELASLRRRLVTAIALAGPVIAVAMIPALQFQHWHWAAL Mflv_2849|M.gilvum_PYR-GCK TE--------DPDLVSLRHRLTGSVLLSVPVIAMAMIPVLQFTYWQWASL MSMEG_5014|M.smegmatis_MC2_155 PE--------DRATDALRTRLLVSAVLTVPVIAMAMVPALQFTNWQWLSL Mvan_4449|M.vanbaalenii_PYR-1 PT--------DDPTAALKRRLLICVALSVPVIAMAMVPVLQFTYWQWLSL TH_4361|M.thermoresistible__bu ATGAAGDD-HDAEAERWRRRLTISAALSIPVVVLSMIPALQFTHWQWLAL MAB_3984c|M.abscessus_ATCC_199 GHDPHDHMNHDVPDDQLKSRLIGSLILAIPVVVISMAMPLHFSGWEILVA Mb0095|M.bovis_AF2122/97 HAR--------QLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQWVLS Rv0092|M.tuberculosis_H37Rv HAR--------QLLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQWVLS MUL_4850|M.ulcerans_Agy99 HAR--------HLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWEWVLT MLBr_02000|M.leprae_Br4923 YAR--------NLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGWGYLLT :: ..: :* * MMAR_0231|M.marinum_M ALAAPVIVWAGRPFHQAAWVNLKHGTATMDTLISVGTLAAFLWSLYALFL MAV_5246|M.avium_104 ALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLYALVL Mflv_2849|M.gilvum_PYR-GCK VLAAPVIVWAAWPFHRAAWANLRHATATMDTLISLGTLSAFLWSLYALFF MSMEG_5014|M.smegmatis_MC2_155 TLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLYALFW Mvan_4449|M.vanbaalenii_PYR-1 TLAAPVVVWGAWPFHQAAWTNLRHGTATMDTLISIGTLAALGWSIYALFW TH_4361|M.thermoresistible__bu TLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLWALFF MAB_3984c|M.abscessus_ATCC_199 ALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLWVLFA Mb0095|M.bovis_AF2122/97 ALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLYTVFG Rv0092|M.tuberculosis_H37Rv ALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLYTVFG MUL_4850|M.ulcerans_Agy99 ALALPVVTWAAWPFHRIALRNARHHGASMETLISVGITAATIWSLYTVFG MLBr_02000|M.leprae_Br4923 ALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLSTIFV .*: *:: * . *** * * :: ::*:**:* * :* **: .:. MMAR_0231|M.marinum_M GTAGEPGMRHPFELTITPGDGAS------NIYLEVAAGVIAFVLAGRYFE MAV_5246|M.avium_104 GAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFE Mflv_2849|M.gilvum_PYR-GCK GTAGTPGMKHPFELTLAPSHGAA------NIYLEVAAGVTTFILAGRYFE MSMEG_5014|M.smegmatis_MC2_155 GTAGVPGMTHPFSLVGSRTDGAG------NIYLEVAAGVTTFILAGRYFE Mvan_4449|M.vanbaalenii_PYR-1 GTAGIPGMTHPFELTIARTDGTS------NIYLEAAAGVTTFILAGRYFE TH_4361|M.thermoresistible__bu TAAGMPGMTMTFTLLPADTGEP-------HIYLEVAAAVTTFIIAGRYFE MAB_3984c|M.abscessus_ATCC_199 NAGHTHGDVH--------------------VYFEVVAAVTVFLLAGRFAE Mb0095|M.bovis_AF2122/97 NHSPIERSGIWQALLGSDA-----------IYFEVAAGVTVFVLVGRYFE Rv0092|M.tuberculosis_H37Rv NHSPIERSGIWQALLGSDA-----------IYFEVAAGVTVFVLVGRYFE MUL_4850|M.ulcerans_Agy99 SHQLADRKGIWQALLGSDA-----------IYFEVAAGVTVFVLAGRYFE MLBr_02000|M.leprae_Br4923 DKEPRQTHGIWQAILHSDS-----------IYFEVAAGVTVFVLAGRFFE :*:*..*.* *::.**: * MMAR_0231|M.marinum_M KRSKRRAGAALQALLELGAKDVAVL-RNGAEIRVPVQELTVDDEFVVRPG MAV_5246|M.avium_104 RRSKRTAGAALRALLALGAKDVAVL-RAGAETRIPIERLAVGDEFVVRPG Mflv_2849|M.gilvum_PYR-GCK KRSKRQAGAALRALLEMGAKEVSVL-RDGVESKIAVEDLVVGDEFVVRPG MSMEG_5014|M.smegmatis_MC2_155 AKSKRRASAALRALMELGAKDVAIL-RNGAEQRIPIDQLGVGDEFVVRPG Mvan_4449|M.vanbaalenii_PYR-1 ARAKRRAGAALRALLELGAREVTVR-RGGAEQRIPIEQLVIGDEFVVRPG TH_4361|M.thermoresistible__bu ARAKRQSGAALRALLDMGANDVAVL-RDGAEKRVPIGELHVGDVFVVRPG MAB_3984c|M.abscessus_ATCC_199 SRAKRSAGSALRALLSLGAKDVAVL-RGGHETRIPVDQLAVGDEFVVRPG Mb0095|M.bovis_AF2122/97 ARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPG Rv0092|M.tuberculosis_H37Rv ARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPG MUL_4850|M.ulcerans_Agy99 ARAKSKAGAALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFVVRPG MLBr_02000|M.leprae_Br4923 ARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFLVRPG ::* :.:**:** .*.:* : * * :. * : *:**** MMAR_0231|M.marinum_M EKIATDGTVVAGSSAVDASMLTGESVPVEVGPGDTVTGATTNAGGRLVVR MAV_5246|M.avium_104 ERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGRLVVR Mflv_2849|M.gilvum_PYR-GCK EKIATDGVVASGTSAVDASMLTGESVPVEVGPGDTVVGATVNAGGRLVVR MSMEG_5014|M.smegmatis_MC2_155 EKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGRLVVR Mvan_4449|M.vanbaalenii_PYR-1 EKIAADGTVVEGASAVDASMLTGESVPEEVQPGDQVVGATVNVDGRLVVR TH_4361|M.thermoresistible__bu EKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGHLQVR MAB_3984c|M.abscessus_ATCC_199 ERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGRIVVR Mb0095|M.bovis_AF2122/97 QIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVE Rv0092|M.tuberculosis_H37Rv QIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVE MUL_4850|M.ulcerans_Agy99 QTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGRLIVE MLBr_02000|M.leprae_Br4923 ETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGRLVIE : :::** . * :::* : :***: * .. .. * *. . *:: :. MMAR_0231|M.marinum_M ATRVGEHTQLAQMAKLVEAAQSGKADVQRLADRVSGVFVPIVIAIAVTTL MAV_5246|M.avium_104 ATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLAVATL Mflv_2849|M.gilvum_PYR-GCK AARVGSDTQLAQMAQLVENAQTGKAQVQRLADRISGVFVPIVLAIAVITL MSMEG_5014|M.smegmatis_MC2_155 ANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALAVATL Mvan_4449|M.vanbaalenii_PYR-1 ADRVGSDTQLAQMARMVEDAQNGKAQAQRLADRISGVFVPIVIALSVATL TH_4361|M.thermoresistible__bu ATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALSALTL MAB_3984c|M.abscessus_ATCC_199 ANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAISALTF Mb0095|M.bovis_AF2122/97 AAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTA Rv0092|M.tuberculosis_H37Rv AAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTA MUL_4850|M.ulcerans_Agy99 AAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIAALTA MLBr_02000|M.leprae_Br4923 ATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMVFVIAGLAG * :* .*::* *.::* ** ** .*:****::.**** *: :: : MMAR_0231|M.marinum_M GVWLG-AGYPVSAALTAAVAVLIIACPCALGLATPTALLVGTGRAAALGV MAV_5246|M.avium_104 AGWLA-AGGTLATALTAAVAVLIIACPCALGLATPTALLVGTGRAAQLGV Mflv_2849|M.gilvum_PYR-GCK GAWLG-AGFPVAAAFTAAVAVLVIACPCALGLATPTALLVGTGRGAQMGV MSMEG_5014|M.smegmatis_MC2_155 GFWLG-TGGSVAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGI Mvan_4449|M.vanbaalenii_PYR-1 GFWIG-SGFPVAAAFTAAVAVLIIACPCALGLATPTALMVGTGRGAQLGI TH_4361|M.thermoresistible__bu AGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGI MAB_3984c|M.abscessus_ATCC_199 VAWAA-LGNSLASAFTAAVAVLIIACPCALGLATPTAILVGTGRGAQLGV Mb0095|M.bovis_AF2122/97 AGWLI-AGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASGRGAQLGI Rv0092|M.tuberculosis_H37Rv AGWLI-AGGQPDRAVSAALAVLVIACPCALGLATPTAMMVASGRGAQLGI MUL_4850|M.ulcerans_Agy99 AGWLL-AGGSPDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGAQLGI MLBr_02000|M.leprae_Br4923 ASWLL-AGASPDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGAQLGI * . *.:..:.**:*****:********::*.:**.* :*: MMAR_0231|M.marinum_M LIKGPEMLESTRRVDTIVLDKTGTVTTGKMTLLEVITVPDT---DRATAL MAV_5246|M.avium_104 LIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT---DRATLL Mflv_2849|M.gilvum_PYR-GCK LIKGPEVLESTRKVDTVVLDKTGTVTTGKMTLVDVVTAPGT---DRGNLL MSMEG_5014|M.smegmatis_MC2_155 LIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE---DRDDVL Mvan_4449|M.vanbaalenii_PYR-1 LIKGPEVLEDTRRVDTVILDKTGTVTTGSMTLVDVFAAEGE---QPDEVL TH_4361|M.thermoresistible__bu LIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL---SETELL MAB_3984c|M.abscessus_ATCC_199 LIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGVADADEIL Mb0095|M.bovis_AF2122/97 FLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EADQVL Rv0092|M.tuberculosis_H37Rv FLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EADQVL MUL_4850|M.ulcerans_Agy99 FLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DADEVL MLBr_02000|M.leprae_Br4923 FIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGGW---CSGEVL ::** . ** . :**:::*****:* * : : * . * MMAR_0231|M.marinum_M RYAGGLEAASEHPIAAAIVKSARAELGALPEPADFANTEGQGVRGIIDGH MAV_5246|M.avium_104 RYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGRVDGH Mflv_2849|M.gilvum_PYR-GCK RLAGALENASEHPIAQAVATAATEELGTLPTPEDFANVEGKGVQGIVDGH MSMEG_5014|M.smegmatis_MC2_155 RVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQGTVEGR Mvan_4449|M.vanbaalenii_PYR-1 RVAGAVESSSEHPIARAIAAGAQEKFGELPAVTAFTNLRGLGVSGQVDGR TH_4361|M.thermoresistible__bu RLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGRVDGH MAB_3984c|M.abscessus_ATCC_199 RIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSGVVDGQ Mb0095|M.bovis_AF2122/97 ALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGTVSGR Rv0092|M.tuberculosis_H37Rv ALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGTVSGR MUL_4850|M.ulcerans_Agy99 AIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGTVSGR MLBr_02000|M.leprae_Br4923 ALASAVEAASEHSVATAIVAAYADPR----PVADFVAFAGCGVSGVVAEH *. :* :***.:* *:. * * ** * : : MMAR_0231|M.marinum_M AVIVGRASLLADWAQHLDPDLAAAKDRAESQGKTAVAVGWDGRARAILVI MAV_5246|M.avium_104 AVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAVGWDGRARGILAL Mflv_2849|M.gilvum_PYR-GCK AVVVGRESLLADWSQHLSPELARAKASAEAQGKTAVAVGWDGEARGVLVV MSMEG_5014|M.smegmatis_MC2_155 AVVVGRPRLFGDPEKSLPRKLADAMEAAQAQGRTAVVVGWDGTARGVLVV Mvan_4449|M.vanbaalenii_PYR-1 AVLLGRLRLLADRSHEIPSELEVAVARAESDGRTAVVVGWDGQARGVLMV TH_4361|M.thermoresistible__bu DVRVGRLAWLG---LSAGDRLRNAAAQAEAAGHTPVWVAVDGRIAGVIVV MAB_3984c|M.abscessus_ATCC_199 EVSI----------------------EAIEGQNTTAAVSWGGLRRGEIEV Mb0095|M.bovis_AF2122/97 AVRVGKPSWIG--SSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIAV Rv0092|M.tuberculosis_H37Rv AVRVGKPSWIG--SSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIAV MUL_4850|M.ulcerans_Agy99 SVRVGKPSWIG--SSSSDTALRAALRNAESLGETAVFVEIDGGPCGVIAV MLBr_02000|M.leprae_Br4923 HVKIGKPSWVTR-NAPCDVVLESARREGESRGETVVFVSVDGVACGAVAI * : . .* . * .* . : : MMAR_0231|M.marinum_M ADTVKPTSAAAIREFKRLGLTPVLLTGDNPTVARHIADEVGID--EVIAD MAV_5246|M.avium_104 ADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG--EVISG Mflv_2849|M.gilvum_PYR-GCK ADTVKPTSAQAISQMREIGLTPVLLTGDNEAVARQIAAEVGID--TVIAE MSMEG_5014|M.smegmatis_MC2_155 ADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID--DVYAE Mvan_4449|M.vanbaalenii_PYR-1 ADAVKPTSAEAISLLKRLGLTPIMVTGDNEAVARAVAAEVGID--EVIAG TH_4361|M.thermoresistible__bu SDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID--DVIAG MAB_3984c|M.abscessus_ATCC_199 ADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAAGDVIAG Mb0095|M.bovis_AF2122/97 ADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--EVIAD Rv0092|M.tuberculosis_H37Rv ADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--EVIAD MUL_4850|M.ulcerans_Agy99 ADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--EVIAN MLBr_02000|M.leprae_Br4923 ADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGID--TVIAD :*:** : *: : * .:::**** * * .:** * : MMAR_0231|M.marinum_M VLPAGKVAAVRRLQSEGKIVAMVGDGVNDAAALATADLGLAMGTGADVAI MAV_5246|M.avium_104 ALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTGTDVAI Mflv_2849|M.gilvum_PYR-GCK VMPKDKVDVIVRLQAEGKTVAMVGDGVNDAPALAQADLGLAMGTGTDVAI MSMEG_5014|M.smegmatis_MC2_155 VLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTGTDVAI Mvan_4449|M.vanbaalenii_PYR-1 VLPQDKVDTVKRLQRDGKVVAMVGDGVNDAAALAQADLGLAMGSGTDVAI TH_4361|M.thermoresistible__bu VLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTGTDVAI MAB_3984c|M.abscessus_ATCC_199 VKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGTGTDAAI Mb0095|M.bovis_AF2122/97 ILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAI Rv0092|M.tuberculosis_H37Rv ILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAI MUL_4850|M.ulcerans_Agy99 ILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRGTDVAI MLBr_02000|M.leprae_Br4923 MLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGLAMGRGTDVAI * *. : :*: *: ***:***:**..*** **:*:::* *:*.** MMAR_0231|M.marinum_M EAADLTLVRGDLRAAADAIRLSRRTLNTIKTNLFWAFGYNVAALPLAAFG MAV_5246|M.avium_104 EAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPLAALG Mflv_2849|M.gilvum_PYR-GCK EASDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFVYNVAAIPVAALG MSMEG_5014|M.smegmatis_MC2_155 EAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAALPLAAAG Mvan_4449|M.vanbaalenii_PYR-1 EASDLTLVSNDLRAVPDAIRLSRKTLSTIKGNLFWAFAYNVAALPLAAAG TH_4361|M.thermoresistible__bu EASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALPLAAAG MAB_3984c|M.abscessus_ATCC_199 EASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAIPLAALG Mb0095|M.bovis_AF2122/97 GAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAAG Rv0092|M.tuberculosis_H37Rv GAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAAG MUL_4850|M.ulcerans_Agy99 GAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIPIAAAG MLBr_02000|M.leprae_Br4923 GAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAIPIASSG *.*: :* . * . *: *. *: *:: *: *** ** **:*:*: * MMAR_0231|M.marinum_M LLNPMLAGAAMAFSSVFVVGNSLRLRSFTSVITDAPPATGSPTRWDATPE MAV_5246|M.avium_104 MLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA--------------- Mflv_2849|M.gilvum_PYR-GCK MLNPMLAGAAMAFSSVFVVGNSLRLRGFTSTSTSSAPTH----------- MSMEG_5014|M.smegmatis_MC2_155 LLNPMLAGAAMAFSSVFVVSNSLRLKRFR--------------------- Mvan_4449|M.vanbaalenii_PYR-1 LLNPMIAGAAMAFSSVFVVSNSLRLRAFTPSR------------------ TH_4361|M.thermoresistible__bu LLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR------------------ MAB_3984c|M.abscessus_ATCC_199 LLNPMIAGAAMAMSSVFVVLNSLRLRTFR--------------------- Mb0095|M.bovis_AF2122/97 LLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA- Rv0092|M.tuberculosis_H37Rv LLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVGGPQMTAPSSA- MUL_4850|M.ulcerans_Agy99 VLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQTTTSTTEPGATE MLBr_02000|M.leprae_Br4923 LLNPLIAGAAMAFSSFFVVSNSLRLSNFG-------------LSQTSD-- :***::******:**.:** ***:* * MMAR_0231|M.marinum_M SPAELSTLPGEPSGCPR MAV_5246|M.avium_104 ----------------- Mflv_2849|M.gilvum_PYR-GCK ----------------- MSMEG_5014|M.smegmatis_MC2_155 ----------------- Mvan_4449|M.vanbaalenii_PYR-1 ----------------- TH_4361|M.thermoresistible__bu ----------------- MAB_3984c|M.abscessus_ATCC_199 ----------------- Mb0095|M.bovis_AF2122/97 ----------------- Rv0092|M.tuberculosis_H37Rv ----------------- MUL_4850|M.ulcerans_Agy99 ----------------- MLBr_02000|M.leprae_Br4923 -----------------