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PTSRARRNWGDDRALLNDEEARDRLLDAAERCVARRGDTQIRMSEVADAANVVRSTVYRYYPSRDDLLLG LVLRRVDRACTRWIRELRRPQDAAASIRELVLLPAASVDSGDPVNLALYAGESTGLATVLEAGAQSVTEI VAGNLKPLFKAWKDEGQIYPDLDLNETVQWMSATSSFLLTPTWRHRSPAAKRRFVDRYLLRALIR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3399 | - | - | 100% (206) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4342 | - | 6e-13 | 29.45% (163) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4911 | - | 6e-12 | 29.32% (191) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 5e-06 | 38.98% (59) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_3024 | - | 9e-20 | 30.81% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 3e-08 | 46.67% (60) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01070 | - | 3e-06 | 30.77% (104) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2606c | - | 1e-12 | 26.23% (183) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3161 | - | 3e-18 | 28.34% (187) | transcriptional regulatory protein |
| M. avium 104 | MAV_5275 | - | 2e-58 | 52.53% (198) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2106 | - | 3e-12 | 29.35% (201) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_4364 | - | 2e-13 | 32.09% (187) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4487 | - | 8e-09 | 33.08% (130) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3399|M.vanbaalenii_PYR-1 -------MPTSRARRNWGDDRALLNDEEARDRLLDAAERCVARRGDTQIR
MAV_5275|M.avium_104 -------MEPS---RRWGDDRAILDDEEARRRILEAAGRCIVRRGNTQFR
Mflv_3024|M.gilvum_PYR-GCK ---------------------------MARDRLLDAAETCLQSKGLSGTT
MMAR_3161|M.marinum_M ---------------MRWGAAAPSDRDSARDRLLDAAERCLESCGVVGTT
Rv1255c|M.tuberculosis_H37Rv --------------MAGTDWLSARRTELAADRILDAAERLFTQRDPASIG
MUL_4487|M.ulcerans_Agy99 --------------MGRTDWLAAHRSEVAADRILDAAERLYTEHDPASIG
MSMEG_2106|M.smegmatis_MC2_155 -----------MARRRGWDGRPPANDEEASARIVEAAVALISETG-SDVS
TH_4364|M.thermoresistible__bu ------------MRTHGWRGTPPRSDDEAVERILAATHRCVAERG-GQTT
MAB_2606c|M.abscessus_ATCC_199 -----------MTAVFDEGSAPESDGDSVTTRLLDATEKLLADKGIRATT
Mb3605|M.bovis_AF2122/97 ------------MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQ
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
:: .:
Mvan_3399|M.vanbaalenii_PYR-1 MSEVADAANVVRSTVYRYYPSRDDLLLGLVLRRVDRACTRWIRELRRP-Q
MAV_5275|M.avium_104 MGEVADEAGVSRSTVYRYFPGRDDVLLGLMLRRVDHALAESVRSLPAP-E
Mflv_3024|M.gilvum_PYR-GCK MEDIARQAGVSRATVYRYFPSRESVVSGVIVRAAQRYLHRISGRISAH-T
MMAR_3161|M.marinum_M MEDIGRTAGVSRATVYRYFPNREAVMSGVIIRAAERYLDRINPRIAEH-T
Rv1255c|M.tuberculosis_H37Rv MNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADV-V
MUL_4487|M.ulcerans_Agy99 MNEIARAAGCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDI-D
MSMEG_2106|M.smegmatis_MC2_155 IADVAASLGVIRQTVYRYFPTADALMRAAAIASVDGFLDRLTAHVRGI-T
TH_4364|M.thermoresistible__bu IAHVAAELGVSRATVYRYFPSTSALLQAAAVEGTRRFLHRMAERLGRI-D
MAB_2606c|M.abscessus_ATCC_199 MTDVAEEAGVSRSWLYRHFPDKPTLVGAAIIRLIEVSWAQSAAELADI-D
Mb3605|M.bovis_AF2122/97 MRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAG-A
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
: :. . .* :: : .
Mvan_3399|M.vanbaalenii_PYR-1 DAAASIRELVLLPAASVDSGDPVNLALYAGESTGLATVLEAGAQSVT--E
MAV_5275|M.avium_104 DPVRSVPQMVLARVESVD-GNPLNEALFAAESTAMASALQKGSEPLV--E
Mflv_3024|M.gilvum_PYR-GCK DLGSAILDFVAVTVRAARREPIIGVLFGSDDELAGVGLAEGTSVALF--E
MMAR_3161|M.marinum_M DLGSALVDFVEYTVEAARREEIIGLLFGSDEELAGVGLAAGTSTSLF--E
Rv1255c|M.tuberculosis_H37Rv EPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIG-GEMAGRSEVIA--A
MUL_4487|M.ulcerans_Agy99 DPRDQLITSITATLRMVRQRPALAAWFASTRPPIG-GELAGQSEVIA--G
MSMEG_2106|M.smegmatis_MC2_155 DPAEAMTDGVLYTLEEVSRTPHLGIVLSEPYLHANSGSLASDEAQDFGMR
TH_4364|M.thermoresistible__bu DVADAIIEGVVQTVAAVPNEPYLRLLLDEP-SHVLLRDVTSESAREIGKS
MAB_2606c|M.abscessus_ATCC_199 GFEARLVAGVKIGRRAYDDPGTLLMRIRLREPEEFMACAGTGVQGLVP--
Mb3605|M.bovis_AF2122/97 TPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEK---
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWID
: :
Mvan_3399|M.vanbaalenii_PYR-1 IVAGNLKPLFKAWKDEGQIYPDLDLNETVQWMS-ATSSFLLTPTWRH--R
MAV_5275|M.avium_104 LLLRHYGPLLERWKAAGLLYPDVDFRSVVQWLH-TATLFLLAPSWRY--R
Mflv_3024|M.gilvum_PYR-GCK LVADFLRPVFAAHWD--QLEAGVSVDDAAEWILRTILSLLSVRGPRH--R
MMAR_3161|M.marinum_M LVTEFLRPIFRRHWS--YVEPGVSVDDAAEWVLRTILSLLTVRGPRE--R
Rv1255c|M.tuberculosis_H37Rv LAAAFLNSLGP--------DDPTTVERRARWVVRMLTSLLMFPG-----R
MUL_4487|M.ulcerans_Agy99 LAAAFLQSLGP--------EAPAAVERRARWTVRVIVSLLMFPG-----Q
MSMEG_2106|M.smegmatis_MC2_155 MLKR-FDVDWAAYG---YDEAAQR--ELVEFTLRIMLSFFVAPNEAT--R
TH_4364|M.thermoresistible__bu MLLESTSVDWARLRP--AAEIVDELDELIEWSLRIVQSFLTDPGDPP--R
MAB_2606c|M.abscessus_ATCC_199 DLAGFWRPYLEAARDTGEIHALTDIEEASEWIARVMISLGSVPGNRIDPD
Mb3605|M.bovis_AF2122/97 LIDSMFARAMANG------EPTEDQYHIARVISDVWLSNLLAWLTRR--A
MLBr_01070|M.leprae_Br4923 YNTAAIQAERKCG-----VAPDTIPAEDLAVALQLMTERVMAATFSDE-K
Mvan_3399|M.vanbaalenii_PYR-1 SPAAKRRFVDRYLLRALIR---------------
MAV_5275|M.avium_104 PHADKRRFVEQFVVRALVPQIRQ-----------
Mflv_3024|M.gilvum_PYR-GCK SPEGLDAFLRRFLLPALLADTQRCVTATIAE---
MMAR_3161|M.marinum_M SRDGLRTFLSRFLLPAILAS-DHCRPM-------
Rv1255c|M.tuberculosis_H37Rv DEADERAMIAEFVVPIVTPASAAARKAGHPGPE-
MUL_4487|M.ulcerans_Agy99 DEADERAMLEEFVAPVVTPFPTRR----------
MSMEG_2106|M.smegmatis_MC2_155 SREELRRFIRRWLGGAL---LAQPRATAAPSSST
TH_4364|M.thermoresistible__bu SPDALRAHLHRWLGPAIREWVASVGIDAEQSPPE
MAB_2606c|M.abscessus_ATCC_199 DPASLRRHFRRYVLPALRIAPVK-----------
Mb3605|M.bovis_AF2122/97 SATDVSKRLDLAVRLLIGDQDSA-----------
MLBr_01070|M.leprae_Br4923 PLIPDKKVIDTLVHIWLASIYGS-----------
. : :