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MGTSEYVRFFEDFGIEDVPLVGGKNASLGEMIQNLSAQGVRVPHGFAITAAAYRHMLDEAGAWERLHAEL DDLDPDDVAALARKAKRAREIVYGAGLPDDLAAEILDGYRALQREYGEEVSLAVRSSATAEDLPTASFAG QQDSYLNIKGEESLLDTCRRCFASLFTDRAIHYRIDQGFDHFKVSLSIGVMKMVRSDIASSGVMFSIDTE SGFRDAVFITGAYGLGENVVQGAVDPDEFYVHKPTYLAGHRAVLRRLLGDKAVKMILVEGETKNTTRNIP TPKADRARFCLTDDDALELAGYACAIEAHYGRPMDMEWAKDGLDGKLYIVQARPETVASQHSVTALESYV LDGHGDILTEGRSVGEKIASGAVRRIEHLAQLSEFKPGEVLVADTTTPDWEPVMKTAAAIVTNRGGRTCH ASIIARELGIPAVVGTGDGTTSVPNGAVVTVSCAEGDTGRVYDGAVGFHVDRTEVGDIARPRTEIMLNLG NPDLAFKTSFLPNDGVGLARMEFIISEYIKVHPLALLHPERVADSEASRTIARLTQGYADGSEFFVERLS EGIGTIAAAFWPKPVVVRMSDFKTNEYASLVGGQSFEPLESNPMLGFRGASRYAHPAYAEGFALECRAMR RVRDEMGLTNVIIMLPFVRRVAEADLVLQTMADLGLKRGENGLKVYAMCEIPNNVILIDQFAKRFDGFSI GSNDLTQLTLGVDRDSEVVAFDYDERDEGVKEMIRLAVEGCRRNGIHSGLCGQAPSDYPDMAEFLVRIGI DSMSLNPDTVVKTTRQVLELERQLASAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4106 | - | - | 100% (798) | phosphoenolpyruvate synthase |
| M. vanbaalenii PYR-1 | Mvan_2632 | - | 4e-37 | 33.82% (340) | pyruvate, water dikinase |
| M. vanbaalenii PYR-1 | Mvan_1818 | - | 1e-21 | 29.93% (274) | pyruvate, water dikinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2073c | - | 1e-11 | 37.01% (127) | hypothetical protein Mb2073c |
| M. gilvum PYR-GCK | Mflv_4990 | - | 1e-127 | 40.05% (794) | phosphoenolpyruvate synthase |
| M. tuberculosis H37Rv | Rv2047c | - | 1e-11 | 37.01% (127) | hypothetical protein Rv2047c |
| M. leprae Br4923 | MLBr_00955 | ppdK | 6e-09 | 31.82% (132) | pyruvate phosphate dikinase |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3410 | - | 0.0 | 84.69% (797) | pyruvate dikinase |
| M. avium 104 | MAV_5056 | - | 4e-13 | 44.59% (74) | PEP-utilizing protein |
| M. smegmatis MC2 155 | MSMEG_3934 | - | 1e-121 | 37.79% (807) | phosphoenolpyruvate synthase |
| M. thermoresistible (build 8) | TH_1154 | - | 1e-126 | 38.86% (808) | phosphoenolpyruvate synthase |
| M. ulcerans Agy99 | MUL_2265 | - | 3e-12 | 37.04% (108) | hypothetical protein MUL_2265 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4106|M.vanbaalenii_PYR-1 ---MGT---SEYVRFFEDFGIEDVPLVGGKN-------ASLGEMIQNLSA
MMAR_3410|M.marinum_M ---MSS---FSYVRFFEEFGIEDVPLVGGKN-------ASLGEMFQKLSQ
Mflv_4990|M.gilvum_PYR-GCK ---MESGTRNTHVCDISALSIGDAEEAGGKG-------ANMGELVA----
TH_1154|M.thermoresistible__bu ---MDH-VADRFVRDIAELRITDAEEAGGKG-------ANMGEMVA----
MSMEG_3934|M.smegmatis_MC2_155 ---MDI-MSDRYVRTLDILTIADAEEAGGKG-------ANLGELVA----
Mb2073c|M.bovis_AF2122/97 MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
Rv2047c|M.tuberculosis_H37Rv MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
MUL_2265|M.ulcerans_Agy99 MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
MAV_5056|M.avium_104 --------------------------------------------------
MLBr_00955|M.leprae_Br4923 --------------------------------------------------
Mvan_4106|M.vanbaalenii_PYR-1 QGVRVPHGFAITAAAYRHMLDEAG-----------AWERLHAELDD--LD
MMAR_3410|M.marinum_M QGVRVPHGFATTADAYKHMLDRAG-----------AWDALHAELDD--LD
Mflv_4990|M.gilvum_PYR-GCK AKLPVPPGFVLLRDCYRDSMRAGG-----------VDAELASLHREALDD
TH_1154|M.thermoresistible__bu AALPVPPGFVLLRDCYLESMQAGG-----------VRSELAALHDEALAK
MSMEG_3934|M.smegmatis_MC2_155 ADLPVPHGFVVMRSAYLDSVRMGG-----------VEAELAALHTEALTH
Mb2073c|M.bovis_AF2122/97 DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG
Rv2047c|M.tuberculosis_H37Rv DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG
MUL_2265|M.ulcerans_Agy99 DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG
MAV_5056|M.avium_104 --------------------------------------------------
MLBr_00955|M.leprae_Br4923 --------------------------------------------------
Mvan_4106|M.vanbaalenii_PYR-1 PDDVAALAR--------------------------KAKRAREIVYGAGLP
MMAR_3410|M.marinum_M ADDVTALAR--------------------------KGKRAREIVYGAGLP
Mflv_4990|M.gilvum_PYR-GCK VADTARLGE--------------------------LCERMQGLVRKAGVD
TH_1154|M.thermoresistible__bu VPDTEQLPA--------------------------LCERLQSLVRKAGMA
MSMEG_3934|M.smegmatis_MC2_155 AADTARLSE--------------------------LCRRMQSLVNKAGLS
Mb2073c|M.bovis_AF2122/97 TGRIVFTSS-------------------------GHQPRVEQMLADCGLE
Rv2047c|M.tuberculosis_H37Rv TGRIVFTSS-------------------------GHQPRVEQMLADCGLE
MUL_2265|M.ulcerans_Agy99 TGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQMLQESGAQ
MAV_5056|M.avium_104 -----------------------------------MTPRACETRRMLMAS
MLBr_00955|M.leprae_Br4923 --------------------------------------------MPGQSH
Mvan_4106|M.vanbaalenii_PYR-1 DDLAAEILDGYRALQREYGEEVSLAVRSSATAEDLPTASFAGQQDSYLNI
MMAR_3410|M.marinum_M EDLASEIVAAYRIMQEEYGEDVSLAVRSSATAEDLPTASFAGQQETFLNI
Mflv_4990|M.gilvum_PYR-GCK DATAADMLAAYHAM----GPGAVVAVRSSATGEDGADASFAGMNATLTNI
TH_1154|M.thermoresistible__bu DEVRKSVLAAYRRL----GPDAVVAVRSSATGEDGRDASFAGMNATMTNV
MSMEG_3934|M.smegmatis_MC2_155 PSVRDATLAAYRAL----GTDVVVAVRSSATGEDGRDASFAGMNRTITNV
Mb2073c|M.bovis_AF2122/97 WVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLLVR
Rv2047c|M.tuberculosis_H37Rv WVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLLVR
MUL_2265|M.ulcerans_Agy99 WVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVLQVVHLDDVLRLLTR
MAV_5056|M.avium_104 MPSASAILTAARTTASRLSPARLIRRHHLPRLAWTRPCGAATIRRRLHFL
MLBr_00955|M.leprae_Br4923 KEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAHDKVDIT
:
Mvan_4106|M.vanbaalenii_PYR-1 KGEESLLDTCRRCFAS--LFTDRAIHYRIDQGFDHFKVSLSIGVMKMVRS
MMAR_3410|M.marinum_M KGEESLLDACRRCFAS--LFTDRAIHYRVDQGFDHFKVALSIGIMKMVRS
Mflv_4990|M.gilvum_PYR-GCK TGDDGLVTAVTRCWMS--LFSPRVITYRASRGFLG-TPAMAVVVQKMIDS
TH_1154|M.thermoresistible__bu AGEDALLEAVVRCWMS--LFSPRVITYRASRGFTD-EPAMAVVVQQMIAS
MSMEG_3934|M.smegmatis_MC2_155 MGEVALLDAVTQCWMS--LFSPRVITYRASRGFTA-APAMAVVVQQMLSA
Mb2073c|M.bovis_AF2122/97 ALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAEL
Rv2047c|M.tuberculosis_H37Rv ALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAEL
MUL_2265|M.ulcerans_Agy99 AVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVG-AALRRIGSVAEF
MAV_5056|M.avium_104 SHVQKVTGVSMRSHSAPEHNAANALHSMSPPGATWSSVNLAEAVPGVMT-
MLBr_00955|M.leprae_Br4923 TSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYNINAMRRHQLAVPPAFC
: .
Mvan_4106|M.vanbaalenii_PYR-1 DIASSGVMFSI---DTESGFRDAVFITGAYGLGENVVQGAVDPDEFYVHK
MMAR_3410|M.marinum_M DLASSGVMFTL---DTESGFNDVVFVTGAYGLGENVVQGAVDPDEFYVHK
Mflv_4990|M.gilvum_PYR-GCK EKS--GVAFTA---DPSTGARDRVVIEAAFGLGEVVVSGSVEPDTYVVSK
TH_1154|M.thermoresistible__bu EKS--GVAFTA---DPSSGAQDRVVVEAAWGLGEVVVAGQVEPDTYVVAK
MSMEG_3934|M.smegmatis_MC2_155 DRA--GVAFTS---DPSTGDADHIVIEAAFGQGEVVVSGKVEPDTYVIDK
Mb2073c|M.bovis_AF2122/97 ELLHSAPLMDVTLLRDRWGFQPAWNAEECLEDFTLAVRGRIGLGKRTFSL
Rv2047c|M.tuberculosis_H37Rv ELLHSAPLMDVTLLRDRWGFQPAWNAEECLEDFTLAVRGRIGLGKRTFSL
MUL_2265|M.ulcerans_Agy99 QLVQGVPVMDTARLHDEWKFQPAFTAEESVEDFALAVRGRVSLGRRVVSL
MAV_5056|M.avium_104 -----PLCASVWVPASELGLREPFVAMGALP----VDRGGIPADPAERIT
MLBr_00955|M.leprae_Br4923 ITTEVGVRYLAAPTPTMEAIWNDVLDQMRWLEAETSRTFGWGPRPLLVSI
Mvan_4106|M.vanbaalenii_PYR-1 PTYLA--GHRAVLRRLLGDKAVKMILVEGET-----KNTTRNIPTPKADR
MMAR_3410|M.marinum_M PTYQA--GHRAVLRRLIGDKAVKMVFVEGGT-----KQTTRNIPTPKADR
Mflv_4990|M.gilvum_PYR-GCK ET-------MEPIDVRLGNKTFKIVRGEDGS-----DTV---VQLDDATA
TH_1154|M.thermoresistible__bu ED-------LGVLDVRIGHKPFKIVRGPDGN-----DQR---VDLPDDQA
MSMEG_3934|M.smegmatis_MC2_155 RT-------LEVRDVRIGFKAIKIVRGDDGA-----DSM---VQLERSQA
Mb2073c|M.bovis_AF2122/97 PWRLANIQDLPAVDSPADDGVAPRLAGPEGANGEFDTPIDPRFPTYLATN
Rv2047c|M.tuberculosis_H37Rv PWRLANIQDLPAVDSPADDGVAPRLAGPEGANGEFDTPIDPRFPTYLATN
MUL_2265|M.ulcerans_Agy99 PWRLANIQDLPAIDASAQDGVVPRLAGPEGVNGEFDTPIDPRFPTFLATN
MAV_5056|M.avium_104 NAFFG---------------------------------------RMAVRV
MLBr_00955|M.leprae_Br4923 RSG----------------------------------------AVQSMPG
Mvan_4106|M.vanbaalenii_PYR-1 ARFCLTDDDALELAGYACAIEAHYGRPMDMEWAKDGLDGKLYIVQARPET
MMAR_3410|M.marinum_M AHFCITDEDVLELAGYALAIEQHYGRPMDIEWAKDGLDGKLYIVQARPET
Mflv_4990|M.gilvum_PYR-GCK ASRVLTDEELHSVAELAVATERHNGCPQDTEWAI--ADGAAYLVQARPIT
TH_1154|M.thermoresistible__bu HARVLDDRELRRIAELAIATEQHNGCPQDTEWAID-AAGEAFLVQARPIT
MSMEG_3934|M.smegmatis_MC2_155 EARVLDDDALRKIATLAVATETHNGCPQDIEWVI--ADGAVWLVQARPIT
Mb2073c|M.bovis_AF2122/97 LSEALPGPFSPSSASVTVRGLRAGGVGIAERLRPSGVIQREIAMRTVAVF
Rv2047c|M.tuberculosis_H37Rv LSEALPGPFSPSSASVTVRGLRAGGVGIAERLRPSGVIQREIAMRTVAVF
MUL_2265|M.ulcerans_Agy99 LSEALPGPFSPSSASVTVRGLRAGGVGIAERLRPGGVIQREIAMRTVAVF
MAV_5056|M.avium_104 DFLCEMGDLIPGQSGEALSRDFFGFVPADFRSRPS--------ARRLPFI
MLBr_00955|M.leprae_Br4923 MMDTILNLGINDPVEQALAAASPSPIPQTFARDT----------RLRFIR
. : :
Mvan_4106|M.vanbaalenii_PYR-1 VASQHSVTALESYVLDGHG-----DILTEGRSVGEKIASGAVRRIEHLAQ
MMAR_3410|M.marinum_M AASQRSMTTVETYVLEGSGEQR--EILTEGRSVGEKVASGVVKRIDDLER
Mflv_4990|M.gilvum_PYR-GCK TLGHTTPPARTEHV-----------VLARGLAAAPGIASGKVRVLQTPDE
TH_1154|M.thermoresistible__bu TLRHAAAPTSEEHV-----------TLARGLAAAPGLASGRVRVLRSPEE
MSMEG_3934|M.smegmatis_MC2_155 TLGSAGSTAGDEPS-----------VLIRGLPAAPGVASGRVRVLLAPDD
Mb2073c|M.bovis_AF2122/97 AHRLYGAITSAHFMAATVPFAKPATIVSNSGFFGPSMASLPIFGAQRPPS
Rv2047c|M.tuberculosis_H37Rv AHRLYGAITSAHFMAATVPFAKPATIVSNSGFFGPSMASLPIFGAQRPPS
MUL_2265|M.ulcerans_Agy99 AHRLYGAITSAHFMAETVPFAKPAMIVSNSGFFGPSMGSLPIFGEERPPA
MAV_5056|M.avium_104 LARYPRTFAG----------------IGRRIARLRSETDAWWRHEIAAVS
MLBr_00955|M.leprae_Br4923 TYRR----------------------IVDPLNPPPANTYDQLRAAIES--
:
Mvan_4106|M.vanbaalenii_PYR-1 LSEFKPGEVLVADTTTPDWEPVMKTAAAIVTNRGGRTCHASIIARELG-I
MMAR_3410|M.marinum_M LSDFKPGQVLVADTTTPDWEPVMKIAAAIVTNRGGRTCHAAIIARELG-I
Mflv_4990|M.gilvum_PYR-GCK GHRLQEGEILVAQMTNPDWLPTIRRAAALVTDTGGMTCHAAIVARELG-V
TH_1154|M.thermoresistible__bu GSQLQDGEILVAPMTNPDWLPTIRRAAALVTDTGGMTCHAAIVARELG-V
MSMEG_3934|M.smegmatis_MC2_155 GDKLTDGEILVAPTTNPDWLPTIRRAAALVTETGGMTCHAAIVARELG-V
Mb2073c|M.bovis_AF2122/97 ESSRARRWLRTLRNIGVFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDN
Rv2047c|M.tuberculosis_H37Rv ESSRARRWLRTLRNIGVFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDN
MUL_2265|M.ulcerans_Agy99 ESSFVRRQLCTVRNIGVFGVNLVGLSAGSALDTNDFIADVDRLEQLAGGD
MAV_5056|M.avium_104 RLDLRLAQRLAAEARDRFFTTLAAQAVISATVIQPVQEQLSTLCKAAGVD
MLBr_00955|M.leprae_Br4923 ----------IFSSWNSPRAVAYRTHYGLDDQSGTAVIVQAMVFGNQG-A
:
Mvan_4106|M.vanbaalenii_PYR-1 PAVVGTGDGTTSVPNGAVVTVSCAEGDTGRVYDGAVGFHVDRTEVGDIAR
MMAR_3410|M.marinum_M PAVVGAGDATTNVPDGQLVTVSCVEGDTGRVYRGEVGFHVDRTEVADLAR
Mflv_4990|M.gilvum_PYR-GCK PCIVGTRTGTRDLHDGTTVTV---DGARGEVASG-VTEPAPQMTVSPRSA
TH_1154|M.thermoresistible__bu PCVVGTRTATRDLHNGTTVTV---DGTHGRVVSGRMASPAAAVTLAEPAA
MSMEG_3934|M.smegmatis_MC2_155 PCVVGARSATVALAVGSMVTV---DGTRGEVTTGRLPETVRTTTTPQEPA
Mb2073c|M.bovis_AF2122/97 LATHDDRRLLSLILLARDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTA
Rv2047c|M.tuberculosis_H37Rv LATHDDRRLLSLILLARDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTA
MUL_2265|M.ulcerans_Agy99 VTTLDDRRLLSLILLARDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTA
MAV_5056|M.avium_104 PAVLLRG----ASHEENAVLHDLWAASRGALEVDEFVKRHGYHGPGE---
MLBr_00955|M.leprae_Br4923 YSGAGTLFSRNPITRESKLFGEWLPGGQGDDVVSGLVEVQPITSLRDE--
*
Mvan_4106|M.vanbaalenii_PYR-1 P----------RTEIMLNLGNPDLAFKTSFLPNDGVG-----LARMEFII
MMAR_3410|M.marinum_M P----------RTEVMVNLGNPDLAFKTSFLPNDGVG-----LARMEFIV
Mflv_4990|M.gilvum_PYR-GCK P--APVTAEVTGTRVYVNLAMPESAETVAAQPVDGVG-----LLRAEFML
TH_1154|M.thermoresistible__bu RPALAAPAEVTATKIYVNLAMPDSAEEVAARGADGVG-----LLRAEFML
MSMEG_3934|M.smegmatis_MC2_155 P---HITGEATGTKVYVNLAMPDSAEAVAAQDVDGVG-----LLRAEFML
Mb2073c|M.bovis_AF2122/97 PAAGPELVSARSVEAVQRLVAAARRDPVVIRLLAEPGERLDKLAVEAPEF
Rv2047c|M.tuberculosis_H37Rv PAAGPELVSARSVEAVQRLVAAARRDPVVIRLLAEPGERLDKLAVEAPEF
MUL_2265|M.ulcerans_Agy99 PAAGPELVSARSVEAVQRLVDAARHDEAVIRLLSEPGDRLGKLAVAAPHF
MAV_5056|M.avium_104 ----------GELETRVWREDPGAVAGLVRRYSARSD-------------
MLBr_00955|M.leprae_Br4923 -----------QPTVYDELVDTAGRLERLGSDVQEIE-------------
.
Mvan_4106|M.vanbaalenii_PYR-1 SEYIKVHPLALLHPERVADSEASRTIARLTQGYADGSEFFVERLSEGIGT
MMAR_3410|M.marinum_M GEYIKVHPLALLHPDKVDDPEARRTIERLTRGYSDGAEFFVQRLSEGIGT
Mflv_4990|M.gilvum_PYR-GCK TEALGGR-----HPR-----------DLIARGEQNM---LVEKMVDSVGR
TH_1154|M.thermoresistible__bu TEALGGR-----HPR-----------DLIARGEQND---LVQGMVNAVGR
MSMEG_3934|M.smegmatis_MC2_155 TEALAGR-----HPR-----------DLITKGEQDT---LVDAMAAAVTR
Mb2073c|M.bovis_AF2122/97 HSAVLAELTLIGHRG-------PAEVEMAATSYADNPELLVRMVAKTLRA
Rv2047c|M.tuberculosis_H37Rv HSAVLAELTLIGHRG-------PAEVEMAATSYADNPELLVRMVAKTLRA
MUL_2265|M.ulcerans_Agy99 YDAVRQELSLIGHRG-------PAEVEMMSTSYADNPELLVGMVAKTLST
MAV_5056|M.avium_104 -----------------------------AESPDADAAEHHRRRSEAERD
MLBr_00955|M.leprae_Br4923 -----------------------------FTTEDSKLWLLQTRVAERSAQ
Mvan_4106|M.vanbaalenii_PYR-1 IAAAFWPKP-VVVRMSDFKTNEYASLVGGQSFEPLESNPMLGFRGASRYA
MMAR_3410|M.marinum_M IAAAFWPKP-VVVRMSDFKSNEYASLIGGSGFEPTESNPMIGFRGASRYA
Mflv_4990|M.gilvum_PYR-GCK IAAAFSPRP-VVYRATDFRSNEFRGLTGGAEYEPVEHNPMIGFRGCYRYV
TH_1154|M.thermoresistible__bu IAAAFAPRP-VVYRATDFRTNEFRGLAGGDRYEPEEHNPMIGYRGCYRYI
MSMEG_3934|M.smegmatis_MC2_155 IGTAFAPRP-VIYRAMDFRTNEFRGLAGGEQFEPVEHNPMIGYRGCYRYI
Mb2073c|M.bovis_AF2122/97 VPAPQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREY
Rv2047c|M.tuberculosis_H37Rv VPAPQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREY
MUL_2265|M.ulcerans_Agy99 SSVPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREH
MAV_5056|M.avium_104 LMSSLGPAARVRARLVLRLARNYIPLRGTG--KVAYLQSLDVLRAAARRI
MLBr_00955|M.leprae_Br4923 VAVRLALQLWQEGLIDDAEALRRVTPVHVETVLLPVLQPENHLSATLLAK
.. .
Mvan_4106|M.vanbaalenii_PYR-1 HP--AYAEGFALECRAMRRVRDEMG-----LTNVIIMLPFVRRVAEADLV
MMAR_3410|M.marinum_M HP--AYAEGFALECRAMQRVRDQMG-----LTNVVIMLPFVRRVAEADLV
Mflv_4990|M.gilvum_PYR-GCK K----EPELFALELEALARVRERS-------PNVALMIPFVRTRWELEEC
TH_1154|M.thermoresistible__bu K----EPDVFALELQALARVREEN-------PNVALMIPFVRTRWELEEC
MSMEG_3934|M.smegmatis_MC2_155 K----EPDLFALELSALARAREHT-------PNIHLMIPFVRTRWELEEC
Mb2073c|M.bovis_AF2122/97 GRRLTEAGVFDTPDDVFYLLVDEID-----ALPADVSGLVARRRAEQRRL
Rv2047c|M.tuberculosis_H37Rv GRRLTEAGVFDTPDDVFYLLVDEID-----ALPADVSGLVARRRAEQRRL
MUL_2265|M.ulcerans_Agy99 GRRLAEAGVLHASDDVFYLLVDEVD-----ALPADVAELVARRRAEQRRL
MAV_5056|M.avium_104 GSLLVEQQRLTDPDDAFYLTIDELTGAPLADAATDLRGTISERREIRAHY
MLBr_00955|M.leprae_Br4923 G---TPTCPGVISGKAYTEVDEALD-----AAESAEQVILVRDHTRPDDV
. : . .
Mvan_4106|M.vanbaalenii_PYR-1 LQTMADLGLKRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFS--IGSND
MMAR_3410|M.marinum_M LETMAEHGLRRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFS--IGSND
Mflv_4990|M.gilvum_PYR-GCK LSLVDASPLGR-QRGLHRWVMAEVPSVVHWLPEYIGMGIDGVS--IGSND
TH_1154|M.thermoresistible__bu LELVDASPLGR-QRGLRRWVMAEVPSVVHWLPEYVGMGIDGVS--IGSND
MSMEG_3934|M.smegmatis_MC2_155 LALVDASPLRR-HRNLHRWVMAEVPSVVHWLPEYVGMGIDGVS--IGSND
Mb2073c|M.bovis_AF2122/97 AGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVRPET
Rv2047c|M.tuberculosis_H37Rv AGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVRPET
MUL_2265|M.ulcerans_Agy99 TAVVPPTVFSGKWEPSTASAAALTAEGTLRGVGVCGGRVRGRVRIVRPET
MAV_5056|M.avium_104 QSLTLPSAWTGQPEPLAPSASAETSVRSLRGIGACAGVAEGRAVVVTDPT
MLBr_00955|M.leprae_Br4923 LGMLASQGVVTEVGGAAS--HAAVVSRELSRVAVVGCGQGTAVSLAGKQI
.
Mvan_4106|M.vanbaalenii_PYR-1 LTQLTLGVDRDSEVVAFDYDERDEGVKEMIRLAVEGCRRNGIHSGLCGQA
MMAR_3410|M.marinum_M LTQLTLGVDRDSEIVAFDYDERDDGVKEMIRLAVEGCRRNGIHSGLCGQA
Mflv_4990|M.gilvum_PYR-GCK LTQLLLGVDRDSDVCAELFDESDPAVLHAIRRIVDTANKFGITSSLCGQA
TH_1154|M.thermoresistible__bu LTQLMLGVDRDSDICAELFDESDAAVLDAIGRIVGTARRLGITSSLCGQA
MSMEG_3934|M.smegmatis_MC2_155 LTQLMLGVDRDSETCAELFDESDAAVLDAISRIISTANRLGITSSLCGQA
Mb2073c|M.bovis_AF2122/97 IDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFP
Rv2047c|M.tuberculosis_H37Rv IDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFP
MUL_2265|M.ulcerans_Agy99 IDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFP
MAV_5056|M.avium_104 ETEIADGDILIAQTTDPSWVSLMFLSAALVVDIGGLMSHAAVMARELGIP
MLBr_00955|M.leprae_Br4923 TVDGDKGEVRQGNLTLSAWSENETPELRELADIARRISPLRVHMTEDHTR
: * .: : : :
Mvan_4106|M.vanbaalenii_PYR-1 PSDYPDMAEFLVRIGIDSMSLNPDTVVKTTRQVLELERQLASAR------
MMAR_3410|M.marinum_M PSDYPDMAEFLVRAGIDSVSLNPDVVVKTTRQILDLEQQVVPLQ------
Mflv_4990|M.gilvum_PYR-GCK PSTNPAFAEHLVRLGITSVSVNPDAVDATRRVIAAAERRIMLAAARSLPE
TH_1154|M.thermoresistible__bu PSTDPAFAEHLVRMGITSVSVNPDALESARRTVAAAERRILLESARNVQG
MSMEG_3934|M.smegmatis_MC2_155 PSTRPEFAEHLVRMGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHPRH
Mb2073c|M.bovis_AF2122/97 CVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR---
Rv2047c|M.tuberculosis_H37Rv CVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR---
MUL_2265|M.ulcerans_Agy99 CVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPADLA-
MAV_5056|M.avium_104 CVMNTGTGTTALRTGDTIRVDGAAGTVEILSRNIQQSSIPERTH------
MLBr_00955|M.leprae_Br4923 LDDSSDTAVRLAINTGHADVVSATPLIVMMTTLRLQDSKDSSAKS-----
. . ..
Mvan_4106|M.vanbaalenii_PYR-1 ----------
MMAR_3410|M.marinum_M ----------
Mflv_4990|M.gilvum_PYR-GCK DQ--------
TH_1154|M.thermoresistible__bu DAPADAR---
MSMEG_3934|M.smegmatis_MC2_155 APTASPRNPL
Mb2073c|M.bovis_AF2122/97 ----------
Rv2047c|M.tuberculosis_H37Rv ----------
MUL_2265|M.ulcerans_Agy99 ----------
MAV_5056|M.avium_104 ----------
MLBr_00955|M.leprae_Br4923 ----------