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MESGTRNTHVCDISALSIGDAEEAGGKGANMGELVAAKLPVPPGFVLLRDCYRDSMRAGGVDAELASLHR EALDDVADTARLGELCERMQGLVRKAGVDDATAADMLAAYHAMGPGAVVAVRSSATGEDGADASFAGMNA TLTNITGDDGLVTAVTRCWMSLFSPRVITYRASRGFLGTPAMAVVVQKMIDSEKSGVAFTADPSTGARDR VVIEAAFGLGEVVVSGSVEPDTYVVSKETMEPIDVRLGNKTFKIVRGEDGSDTVVQLDDATAASRVLTDE ELHSVAELAVATERHNGCPQDTEWAIADGAAYLVQARPITTLGHTTPPARTEHVVLARGLAAAPGIASGK VRVLQTPDEGHRLQEGEILVAQMTNPDWLPTIRRAAALVTDTGGMTCHAAIVARELGVPCIVGTRTGTRD LHDGTTVTVDGARGEVASGVTEPAPQMTVSPRSAPAPVTAEVTGTRVYVNLAMPESAETVAAQPVDGVGL LRAEFMLTEALGGRHPRDLIARGEQNMLVEKMVDSVGRIAAAFSPRPVVYRATDFRSNEFRGLTGGAEYE PVEHNPMIGFRGCYRYVKEPELFALELEALARVRERSPNVALMIPFVRTRWELEECLSLVDASPLGRQRG LHRWVMAEVPSVVHWLPEYIGMGIDGVSIGSNDLTQLLLGVDRDSDVCAELFDESDPAVLHAIRRIVDTA NKFGITSSLCGQAPSTNPAFAEHLVRLGITSVSVNPDAVDATRRVIAAAERRIMLAAARSLPEDQ
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4990 | - | - | 100% (765) | phosphoenolpyruvate synthase |
M. gilvum PYR-GCK | Mflv_0749 | - | 4e-32 | 30.60% (402) | phosphoenolpyruvate-protein phosphotransferase |
M. gilvum PYR-GCK | Mflv_0493 | - | 2e-29 | 33.11% (299) | pyruvate, water dikinase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1158c | ppdK | 1e-19 | 26.12% (448) | pyruvate phosphate dikinase |
M. tuberculosis H37Rv | Rv1127c | ppdK | 2e-19 | 26.44% (450) | pyruvate phosphate dikinase |
M. leprae Br4923 | MLBr_00955 | ppdK | 3e-17 | 28.05% (303) | pyruvate phosphate dikinase |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_3410 | - | 1e-127 | 39.00% (800) | pyruvate dikinase |
M. avium 104 | MAV_1960 | - | 7e-23 | 27.59% (453) | pyruvate phosphate dikinase |
M. smegmatis MC2 155 | MSMEG_3934 | - | 0.0 | 70.84% (751) | phosphoenolpyruvate synthase |
M. thermoresistible (build 8) | TH_1154 | - | 0.0 | 76.42% (759) | phosphoenolpyruvate synthase |
M. ulcerans Agy99 | MUL_0141 | ppdK | 1e-19 | 27.69% (455) | pyruvate phosphate dikinase |
M. vanbaalenii PYR-1 | Mvan_4106 | - | 1e-127 | 40.05% (794) | phosphoenolpyruvate synthase |
CLUSTAL 2.0.9 multiple sequence alignment Mb1158c|M.bovis_AF2122/97 ---------------MTR-------------------------------- Rv1127c|M.tuberculosis_H37Rv ---------------MTR-------------------------------- MUL_0141|M.ulcerans_Agy99 MP------KTTRGCTTTR-------------------------------- MLBr_00955|M.leprae_Br4923 MPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAH MAV_1960|M.avium_104 ---------------MPR-------------------------------- Mflv_4990|M.gilvum_PYR-GCK ---------------MESG------------------------------- TH_1154|M.thermoresistible__bu ---------------MDH-------------------------------- MSMEG_3934|M.smegmatis_MC2_155 ---------------MDI-------------------------------- MMAR_3410|M.marinum_M ---------------MSS-------------------------------- Mvan_4106|M.vanbaalenii_PYR-1 ---------------MGT-------------------------------- Mb1158c|M.bovis_AF2122/97 ----ITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRR---- Rv1127c|M.tuberculosis_H37Rv ----ITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRR---- MUL_0141|M.ulcerans_Agy99 ----FSRAGGIP--FTGPAVVLLDGRAHQPREVLGNKGHGIDSMRR---- MLBr_00955|M.leprae_Br4923 DKVDITTSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYNINAMRR---- MAV_1960|M.avium_104 --------------TAHTSVVLLDGSAQLPRETLGNKGYGLNIMRR---- Mflv_4990|M.gilvum_PYR-GCK --------------TRNTHVCDISALSIGDAEEAGGKGANMGELVA---- TH_1154|M.thermoresistible__bu --------------VADRFVRDIAELRITDAEEAGGKGANMGEMVA---- MSMEG_3934|M.smegmatis_MC2_155 --------------MSDRYVRTLDILTIADAEEAGGKGANLGELVA---- MMAR_3410|M.marinum_M ----------------FSYVRFFEEFGIEDVPLVGGKNASLGEMFQKLSQ Mvan_4106|M.vanbaalenii_PYR-1 ----------------SEYVRFFEDFGIEDVPLVGGKNASLGEMIQNLSA : : *.*. .:. : Mb1158c|M.bovis_AF2122/97 HHLPVPPAFCITTEVGVRYLAAPESTIAAIWDDVLDRMSWLETETSCTFG Rv1127c|M.tuberculosis_H37Rv HHLPVPPAFCITTEVGVRYLAAPGSTIAAIWDDVLDRMSWLETETSCTFG MUL_0141|M.ulcerans_Agy99 NNLPVPPAFCITSEVGVRYLADPAPTLDAIWDDVVDRIRWLEAETGRTFG MLBr_00955|M.leprae_Br4923 HQLAVPPAFCITTEVGVRYLAAPTPTMEAIWNDVLDQMRWLEAETSRTFG MAV_1960|M.avium_104 NGLPVPPAFCITTEICAQWLDDPGTTIDGLSETLTQMIHCLEEQTSRTFG Mflv_4990|M.gilvum_PYR-GCK AKLPVPPGFVLLRDCYRDSMRAGG-VDAELASLHREALDDVADTARLGEL TH_1154|M.thermoresistible__bu AALPVPPGFVLLRDCYLESMQAGG-VRSELAALHDEALAKVPDTEQLPAL MSMEG_3934|M.smegmatis_MC2_155 ADLPVPHGFVVMRSAYLDSVRMGG-VEAELAALHTEALTHAADTARLSEL MMAR_3410|M.marinum_M QGVRVPHGFATTADAYKHMLDRAG-AWDALHAELDD--LDADDVTALARK Mvan_4106|M.vanbaalenii_PYR-1 QGVRVPHGFAITAAAYRHMLDEAG-AWERLHAELDD--LDPDDVAALARK : ** .* : . : : Mb1158c|M.bovis_AF2122/97 RGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPG----AADF Rv1127c|M.tuberculosis_H37Rv RGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPG----AADF MUL_0141|M.ulcerans_Agy99 SGPHPLLVSVRSGANQSMPGMMDTILDLGMNDTVEQALASPG----TGDF MLBr_00955|M.leprae_Br4923 WGPRPLLVSIRSGAVQSMPGMMDTILNLGINDPVEQALAAASPSPIPQTF MAV_1960|M.avium_104 RGPRPLLVSVRSGAALSMPGMMDTVLNLGMNDTVEQALAQTF----SARF Mflv_4990|M.gilvum_PYR-GCK CERMQGLVRKAGVDDATAADMLAAYHAM----GPGAVVAVRS----SATG TH_1154|M.thermoresistible__bu CERLQSLVRKAGMADEVRKSVLAAYRRL----GPDAVVAVRS----SATG MSMEG_3934|M.smegmatis_MC2_155 CRRMQSLVNKAGLSPSVRDATLAAYRAL----GTDVVVAVRS----SATG MMAR_3410|M.marinum_M GKRAREIVYGAGLPEDLASEIVAAYRIMQEEYGEDVSLAVRS----SATA Mvan_4106|M.vanbaalenii_PYR-1 AKRAREIVYGAGLPDDLAAEILDGYRALQREYGEEVSLAVRS----SATA :* . : : :* . Mb1158c|M.bovis_AF2122/97 AHDTRRRFTSMYRRIVGS---AGPITDDPYAQLRASIEAVFASWNSPRAV Rv1127c|M.tuberculosis_H37Rv AHDTRRRFTSMYRRIVGS---AGPITDDPYAQLRASIEAVFASWNSPRAV MUL_0141|M.ulcerans_Agy99 ARDTRRRFTRMYRRIVAG---SDPP-DDPYEQLRAGIGAVFASWNSPRAI MLBr_00955|M.leprae_Br4923 ARDTRLRFIRTYRRIVDP---LNPPPANTYDQLRAAIESIFSSWNSPRAV MAV_1960|M.avium_104 AMDTRARFADMYRRIVLDGDASAAVPDDPFLQLLGAIEAVFASWNSPRAV Mflv_4990|M.gilvum_PYR-GCK EDGADASFAGMNATLTNIT---------GDDGLVTAVTRCWMSLFSPRVI TH_1154|M.thermoresistible__bu EDGRDASFAGMNATMTNVA---------GEDALLEAVVRCWMSLFSPRVI MSMEG_3934|M.smegmatis_MC2_155 EDGRDASFAGMNRTITNVM---------GEVALLDAVTQCWMSLFSPRVI MMAR_3410|M.marinum_M EDLPTASFAGQQETFLNIK---------GEESLLDACRRCFASLFTDRAI Mvan_4106|M.vanbaalenii_PYR-1 EDLPTASFAGQQDSYLNIK---------GEESLLDTCRRCFASLFTDRAI * * : * : *.: Mb1158c|M.bovis_AF2122/97 AYRDHHGLDD-QGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFG Rv1127c|M.tuberculosis_H37Rv AYRDHHGLDD-QGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFG MUL_0141|M.ulcerans_Agy99 AYRNHYSLDD-QGGTAVVVQAMVFGNRSADSGAGVLSSRNPITGASEPFG MLBr_00955|M.leprae_Br4923 AYRTHYGLDD-QSGTAVIVQAMVFGNQGAYSGAGTLFSRNPITRESKLFG MAV_1960|M.avium_104 AYRKHHGRDD-LGGTAVVVQAMVFGNMESNSGTGVLFSRNPITGADEPFG Mflv_4990|M.gilvum_PYR-GCK TYRASRGFLG-TPAMAVVVQKMIDSEKS-----GVAFTADPSTGARDRVV TH_1154|M.thermoresistible__bu TYRASRGFTD-EPAMAVVVQQMIASEKS-----GVAFTADPSSGAQDRVV MSMEG_3934|M.smegmatis_MC2_155 TYRASRGFTA-APAMAVVVQQMLSADRA-----GVAFTSDPSTGDADHIV MMAR_3410|M.marinum_M HYRVDQGFDHFKVALSIGIMKMVRSDLAS---SGVMFTLDTESGFNDVVF Mvan_4106|M.vanbaalenii_PYR-1 HYRIDQGFDHFKVSLSIGVMKMVRSDIAS---SGVMFSIDTESGFRDAVF ** . . :: : *: .: *. : :. : . . Mb1158c|M.bovis_AF2122/97 EWLPGGQGDDVVSGLVAVAPITALRDQ---------QPAVYDQLMAAARS Rv1127c|M.tuberculosis_H37Rv EWLPGGQGDDVVSGLVAVAPITALRDQ---------QPAVYDQLMAAARS MUL_0141|M.ulcerans_Agy99 EWLPGGQGDDVVSGLLKVEPITALRDR---------LPKIYLELLDAARG MLBr_00955|M.leprae_Br4923 EWLPGGQGDDVVSGLVEVQPITSLRDE---------QPTVYDELVDTAGR MAV_1960|M.avium_104 EWLSSGQGEDVVSGTFDARPISVLAEE---------QPHVYDELVAAART Mflv_4990|M.gilvum_PYR-GCK IEAAFGLGEVVVSGSVEPDTYVVSKET-----MEPIDVRLGNKTFKIVRG TH_1154|M.thermoresistible__bu VEAAWGLGEVVVAGQVEPDTYVVAKED-----LGVLDVRIGHKPFKIVRG MSMEG_3934|M.smegmatis_MC2_155 IEAAFGQGEVVVSGKVEPDTYVIDKRT-----LEVRDVRIGFKAIKIVRG MMAR_3410|M.marinum_M VTGAYGLGENVVQGAVDPDEFYVHKPTYQAGHRAVLRRLIGDKAVKMVFV Mvan_4106|M.vanbaalenii_PYR-1 ITGAYGLGENVVQGAVDPDEFYVHKPTYLAGHRAVLRRLLGDKAVKMILV . * *: ** * . : : . Mb1158c|M.bovis_AF2122/97 LERMAGDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQLHH----EG Rv1127c|M.tuberculosis_H37Rv LERMAGDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQLHH----EG MUL_0141|M.ulcerans_Agy99 LERLAAEVQEVEFTVESGKLWLLQTRSAERSAQAAVRLALQLRG----AG MLBr_00955|M.leprae_Br4923 LERLGSDVQEIEFTTEDSKLWLLQTRVAERSAQVAVRLALQLWQ----EG MAV_1960|M.avium_104 LERLGSDVQDIEYTVEEGKLWLLQTRAAKRSAQAAVRLALKLRD----EG Mflv_4990|M.gilvum_PYR-GCK EDGSDTV---VQLDDATAASRVLTDEELHSVAELAVATERHNGCPQDTEW TH_1154|M.thermoresistible__bu PDGNDQR---VDLPDDQAHARVLDDRELRRIAELAIATEQHNGCPQDTEW MSMEG_3934|M.smegmatis_MC2_155 DDGADSM---VQLERSQAEARVLDDDALRKIATLAVATETHNGCPQDIEW MMAR_3410|M.marinum_M EGGTKQTTRNIPTPKADRAHFCITDEDVLELAGYALAIEQHYGRPMDIEW Mvan_4106|M.vanbaalenii_PYR-1 EGETKNTTRNIPTPKADRARFCLTDDDALELAGYACAIEAHYGRPMDMEW : : * * : Mb1158c|M.bovis_AF2122/97 LIDDTETLRRVTPTHIETLLRPSLQPETRLAAP--------LLAKGLPAC Rv1127c|M.tuberculosis_H37Rv LIDDTETLRRVTPTHIETLLRPSLQTETRLAAP--------LLAKGLPAC MUL_0141|M.ulcerans_Agy99 LIDDGETLRRITPTHVETLLLPTLHPDERLAAS--------LLAKGLPAC MLBr_00955|M.leprae_Br4923 LIDDAEALRRVTPVHVETVLLPVLQPENHLSAT--------LLAKGTPTC MAV_1960|M.avium_104 LIDDMETLRRVTPAHIETLLMPSLQPETRLAAP--------LLAKGLPAC Mflv_4990|M.gilvum_PYR-GCK AI--ADGAAYLVQARPITTLGHTTPPARTEHV---------VLARGLAAA TH_1154|M.thermoresistible__bu AID-AAGEAFLVQARPITTLRHAAAPTSEEHV---------TLARGLAAA MSMEG_3934|M.smegmatis_MC2_155 VI--ADGAVWLVQARPITTLGSAGSTAGDEPS---------VLIRGLPAA MMAR_3410|M.marinum_M AKDGLDGKLYIVQARPETAASQRSMTTVETYVLEGSGEQREILTEGRSVG Mvan_4106|M.vanbaalenii_PYR-1 AKDGLDGKLYIVQARPETVASQHSVTALESYVLDGHG---DILTEGRSVG :. .: * . * .* .. Mb1158c|M.bovis_AF2122/97 PGVVSGTAYTEVDEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEV Rv1127c|M.tuberculosis_H37Rv PGVVSGTAYTEVDEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEV MUL_0141|M.ulcerans_Agy99 PGVAAGLAYTDVDEALDAADRGEQVILVRDHTRPEDVSGMLAAQGIVTEI MLBr_00955|M.leprae_Br4923 PGVISGKAYTEVDEALDAAESAEQVILVRDHTRPDDVLGMLASQGVVTEV MAV_1960|M.avium_104 PGVVSGRAVTDVYDAIDAAEDGQDVILVRRSTSPDDVQGMIAALGIVTGI Mflv_4990|M.gilvum_PYR-GCK PGIASG-KVRVLQTPDEGHRLQEGEILVAQMTNPDWLPTIRRAAALVTDT TH_1154|M.thermoresistible__bu PGLASG-RVRVLRSPEEGSQLQDGEILVAPMTNPDWLPTIRRAAALVTDT MSMEG_3934|M.smegmatis_MC2_155 PGVASG-RVRVLLAPDDGDKLTDGEILVAPTTNPDWLPTIRRAAALVTET MMAR_3410|M.marinum_M EKVASG-VVKRIDDLERLSDFKPGQVLVADTTTPDWEPVMKIAAAIVTNR Mvan_4106|M.vanbaalenii_PYR-1 EKIASG-AVRRIEHLAQLSEFKPGEVLVADTTTPDWEPVMKTAAAIVTNR : :* : :** * *: : : .:** Mb1158c|M.bovis_AF2122/97 GGAASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVD---GYEGEVRQG Rv1127c|M.tuberculosis_H37Rv GGAASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVD---GYEGEVRQG MUL_0141|M.ulcerans_Agy99 GGAASHAAVVSRELGRVAVVGCGDGVAASLAGKRITVD---GYTGEVREG MLBr_00955|M.leprae_Br4923 GGAASHAAVVSRELSRVAVVGCGQGTAVSLAGKQITVD---GDKGEVRQG MAV_1960|M.avium_104 GGTTSHAAVVSRELGRPSVVGCGADVTDALAGKLITVD---GTEGEVREG Mflv_4990|M.gilvum_PYR-GCK GGMTCHAAIVARELGVPCIVGTRTGTRDLHDGTTVTV---DGARGEVASG TH_1154|M.thermoresistible__bu GGMTCHAAIVARELGVPCVVGTRTATRDLHNGTTVTV---DGTHGRVVSG MSMEG_3934|M.smegmatis_MC2_155 GGMTCHAAIVARELGVPCVVGARSATVALAVGSMVTV---DGTRGEVTTG MMAR_3410|M.marinum_M GGRTCHAAIIARELGIPAVVGAGDATTNVPDGQLVTVSCVEGDTGRVYRG Mvan_4106|M.vanbaalenii_PYR-1 GGRTCHASIIARELGIPAVVGTGDGTTSVPNGAVVTVSCAEGDTGRVYDG ** :.**::::***. .:** . * :** * *.* * Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0141|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_1960|M.avium_104 -------------------------------------------------- Mflv_4990|M.gilvum_PYR-GCK -VTEPAPQMTVSPRSAP--APVTAEVTGTRVYVNLAMPESAETVAAQPVD TH_1154|M.thermoresistible__bu RMASPAAAVTLAEPAARPALAAPAEVTATKIYVNLAMPDSAEEVAARGAD MSMEG_3934|M.smegmatis_MC2_155 RLPETVRTTTTPQEPAP---HITGEATGTKVYVNLAMPDSAEAVAAQDVD MMAR_3410|M.marinum_M EVGFHVDRTEVADLARP----------RTEVMVNLGNPDLAFKTSFLPND Mvan_4106|M.vanbaalenii_PYR-1 AVGFHVDRTEVGDIARP----------RTEIMLNLGNPDLAFKTSFLPND Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0141|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_1960|M.avium_104 -------------------------------------------------- Mflv_4990|M.gilvum_PYR-GCK GVGLLRAEFMLTEALGGR-----HPR-----------DLIARGEQNM--- TH_1154|M.thermoresistible__bu GVGLLRAEFMLTEALGGR-----HPR-----------DLIARGEQND--- MSMEG_3934|M.smegmatis_MC2_155 GVGLLRAEFMLTEALAGR-----HPR-----------DLITKGEQDT--- MMAR_3410|M.marinum_M GVGLARMEFIVGEYIKVHPLALLHPDKVDDPEARRTIERLTRGYSDGAEF Mvan_4106|M.vanbaalenii_PYR-1 GVGLARMEFIISEYIKVHPLALLHPERVADSEASRTIARLTQGYADGSEF Mb1158c|M.bovis_AF2122/97 ---------------------VLALSAWSESDTPELR------------- Rv1127c|M.tuberculosis_H37Rv ---------------------VLALSAWSESDTPELR------------- MUL_0141|M.ulcerans_Agy99 ---------------------ILAPSAWSEDDTPELR------------- MLBr_00955|M.leprae_Br4923 ---------------------NLTLSAWSENETPELR------------- MAV_1960|M.avium_104 ---------------------ILELTAWSEDDSSDLA------------- Mflv_4990|M.gilvum_PYR-GCK LVEKMVDSVGRIAAAFSPRPVVYRATDFRSNEFRGLTGGAEYEPVEHNPM TH_1154|M.thermoresistible__bu LVQGMVNAVGRIAAAFAPRPVVYRATDFRTNEFRGLAGGDRYEPEEHNPM MSMEG_3934|M.smegmatis_MC2_155 LVDAMAAAVTRIGTAFAPRPVIYRAMDFRTNEFRGLAGGEQFEPVEHNPM MMAR_3410|M.marinum_M FVQRLSEGIGTIAAAFWPKPVVVRMSDFKSNEYASLIGGSGFEPTESNPM Mvan_4106|M.vanbaalenii_PYR-1 FVERLSEGIGTIAAAFWPKPVVVRMSDFKTNEYASLVGGQSFEPLESNPM : .: * Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0141|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_1960|M.avium_104 -------------------------------------------------- Mflv_4990|M.gilvum_PYR-GCK IGFRGCYRYVK--EPELFALELEALARVRERS--PNVALMIPFVRTRWEL TH_1154|M.thermoresistible__bu IGYRGCYRYIK--EPDVFALELQALARVREEN--PNVALMIPFVRTRWEL MSMEG_3934|M.smegmatis_MC2_155 IGYRGCYRYIK--EPDLFALELSALARAREHT--PNIHLMIPFVRTRWEL MMAR_3410|M.marinum_M IGFRGASRYAHPAYAEGFALECRAMQRVRDQMGLTNVVIMLPFVRRVAEA Mvan_4106|M.vanbaalenii_PYR-1 LGFRGASRYAHPAYAEGFALECRAMRRVRDEMGLTNVIIMLPFVRRVAEA Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0141|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_1960|M.avium_104 -------------------------------------------------- Mflv_4990|M.gilvum_PYR-GCK EECLSLVDASPLGR-QRGLHRWVMAEVPSVVHWLPEYIGMGIDGVSIGSN TH_1154|M.thermoresistible__bu EECLELVDASPLGR-QRGLRRWVMAEVPSVVHWLPEYVGMGIDGVSIGSN MSMEG_3934|M.smegmatis_MC2_155 EECLALVDASPLRR-HRNLHRWVMAEVPSVVHWLPEYVGMGIDGVSIGSN MMAR_3410|M.marinum_M DLVLETMAEHGLRRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFSIGSN Mvan_4106|M.vanbaalenii_PYR-1 DLVLQTMADLGLKRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFSIGSN Mb1158c|M.bovis_AF2122/97 ELADIAQRISS--------------------------------------- Rv1127c|M.tuberculosis_H37Rv ELADIAQRISS--------------------------------------- MUL_0141|M.ulcerans_Agy99 DLTTIALKISPLRAHASGDYPKLDDPSEAGVLTAMAAG-----YTDVVSD MLBr_00955|M.leprae_Br4923 ELADIARRISPLRVHMTEDHTRLDDSSDTAVRLAINTG-----HADVVSA MAV_1960|M.avium_104 ELTRIALAVSPLRAHTTGDYPPLDAGSDDAVRAALAAG-----HTDVLSS Mflv_4990|M.gilvum_PYR-GCK DLTQLLLGVDRDSDVCAELFDESDPAVLHAIRRIVDTANKFGITSSLCGQ TH_1154|M.thermoresistible__bu DLTQLMLGVDRDSDICAELFDESDAAVLDAIGRIVGTARRLGITSSLCGQ MSMEG_3934|M.smegmatis_MC2_155 DLTQLMLGVDRDSETCAELFDESDAAVLDAISRIISTANRLGITSSLCGQ MMAR_3410|M.marinum_M DLTQLTLGVDRDSEIVAFDYDERDDGVKEMIRLAVEGCRRNGIHSGLCGQ Mvan_4106|M.vanbaalenii_PYR-1 DLTQLTLGVDRDSEVVAFDYDERDEGVKEMIRLAVEGCRRNGIHSGLCGQ :*: : :. Mb1158c|M.bovis_AF2122/97 -------------------------------------------------- Rv1127c|M.tuberculosis_H37Rv -------------------------------------------------- MUL_0141|M.ulcerans_Agy99 AP----------LITMLNALRVQDGL------------------------ MLBr_00955|M.leprae_Br4923 TP----------LIVMMTTLRLQDSKDSSAKS------------------ MAV_1960|M.avium_104 TP----------LITMLTAVRLAGTDTRELSR------------------ Mflv_4990|M.gilvum_PYR-GCK APSTNPAFAEHLVRLGITSVSVNPDAVDATRRVIAAAERRIMLAAARSLP TH_1154|M.thermoresistible__bu APSTDPAFAEHLVRMGITSVSVNPDALESARRTVAAAERRILLESARNVQ MSMEG_3934|M.smegmatis_MC2_155 APSTRPEFAEHLVRMGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHPR MMAR_3410|M.marinum_M APSDYPDMAEFLVRAGIDSVSLNPDVVVKTTRQILDLEQQVVPLQ----- Mvan_4106|M.vanbaalenii_PYR-1 APSDYPDMAEFLVRIGIDSMSLNPDTVVKTTRQVLELERQLASAR----- Mb1158c|M.bovis_AF2122/97 ----------- Rv1127c|M.tuberculosis_H37Rv ----------- MUL_0141|M.ulcerans_Agy99 ----------- MLBr_00955|M.leprae_Br4923 ----------- MAV_1960|M.avium_104 ----------- Mflv_4990|M.gilvum_PYR-GCK EDQ-------- TH_1154|M.thermoresistible__bu GDAPADAR--- MSMEG_3934|M.smegmatis_MC2_155 HAPTASPRNPL MMAR_3410|M.marinum_M ----------- Mvan_4106|M.vanbaalenii_PYR-1 -----------