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M. gilvum PYR-GCK Mflv_4990 (-)

annotation: phosphoenolpyruvate synthase
coordinates: 5312408 - 5314705
length: 765

MESGTRNTHVCDISALSIGDAEEAGGKGANMGELVAAKLPVPPGFVLLRDCYRDSMRAGGVDAELASLHR
EALDDVADTARLGELCERMQGLVRKAGVDDATAADMLAAYHAMGPGAVVAVRSSATGEDGADASFAGMNA
TLTNITGDDGLVTAVTRCWMSLFSPRVITYRASRGFLGTPAMAVVVQKMIDSEKSGVAFTADPSTGARDR
VVIEAAFGLGEVVVSGSVEPDTYVVSKETMEPIDVRLGNKTFKIVRGEDGSDTVVQLDDATAASRVLTDE
ELHSVAELAVATERHNGCPQDTEWAIADGAAYLVQARPITTLGHTTPPARTEHVVLARGLAAAPGIASGK
VRVLQTPDEGHRLQEGEILVAQMTNPDWLPTIRRAAALVTDTGGMTCHAAIVARELGVPCIVGTRTGTRD
LHDGTTVTVDGARGEVASGVTEPAPQMTVSPRSAPAPVTAEVTGTRVYVNLAMPESAETVAAQPVDGVGL
LRAEFMLTEALGGRHPRDLIARGEQNMLVEKMVDSVGRIAAAFSPRPVVYRATDFRSNEFRGLTGGAEYE
PVEHNPMIGFRGCYRYVKEPELFALELEALARVRERSPNVALMIPFVRTRWELEECLSLVDASPLGRQRG
LHRWVMAEVPSVVHWLPEYIGMGIDGVSIGSNDLTQLLLGVDRDSDVCAELFDESDPAVLHAIRRIVDTA
NKFGITSSLCGQAPSTNPAFAEHLVRLGITSVSVNPDAVDATRRVIAAAERRIMLAAARSLPEDQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4990--100% (765)phosphoenolpyruvate synthase
M. gilvum PYR-GCKMflv_0749-4e-3230.60% (402) phosphoenolpyruvate-protein phosphotransferase
M. gilvum PYR-GCKMflv_0493-2e-2933.11% (299) pyruvate, water dikinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1158cppdK1e-1926.12% (448) pyruvate phosphate dikinase
M. tuberculosis H37RvRv1127cppdK2e-1926.44% (450) pyruvate phosphate dikinase
M. leprae Br4923MLBr_00955ppdK3e-1728.05% (303) pyruvate phosphate dikinase
M. abscessus ATCC 19977-----
M. marinum MMMAR_3410-1e-12739.00% (800) pyruvate dikinase
M. avium 104MAV_1960-7e-2327.59% (453) pyruvate phosphate dikinase
M. smegmatis MC2 155MSMEG_3934-0.070.84% (751) phosphoenolpyruvate synthase
M. thermoresistible (build 8)TH_1154-0.076.42% (759) phosphoenolpyruvate synthase
M. ulcerans Agy99MUL_0141ppdK1e-1927.69% (455) pyruvate phosphate dikinase
M. vanbaalenii PYR-1Mvan_4106-1e-12740.05% (794) phosphoenolpyruvate synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1158c|M.bovis_AF2122/97           ---------------MTR--------------------------------
Rv1127c|M.tuberculosis_H37Rv        ---------------MTR--------------------------------
MUL_0141|M.ulcerans_Agy99           MP------KTTRGCTTTR--------------------------------
MLBr_00955|M.leprae_Br4923          MPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAH
MAV_1960|M.avium_104                ---------------MPR--------------------------------
Mflv_4990|M.gilvum_PYR-GCK          ---------------MESG-------------------------------
TH_1154|M.thermoresistible__bu      ---------------MDH--------------------------------
MSMEG_3934|M.smegmatis_MC2_155      ---------------MDI--------------------------------
MMAR_3410|M.marinum_M               ---------------MSS--------------------------------
Mvan_4106|M.vanbaalenii_PYR-1       ---------------MGT--------------------------------
                                                                                      

Mb1158c|M.bovis_AF2122/97           ----ITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRR----
Rv1127c|M.tuberculosis_H37Rv        ----ITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRR----
MUL_0141|M.ulcerans_Agy99           ----FSRAGGIP--FTGPAVVLLDGRAHQPREVLGNKGHGIDSMRR----
MLBr_00955|M.leprae_Br4923          DKVDITTSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYNINAMRR----
MAV_1960|M.avium_104                --------------TAHTSVVLLDGSAQLPRETLGNKGYGLNIMRR----
Mflv_4990|M.gilvum_PYR-GCK          --------------TRNTHVCDISALSIGDAEEAGGKGANMGELVA----
TH_1154|M.thermoresistible__bu      --------------VADRFVRDIAELRITDAEEAGGKGANMGEMVA----
MSMEG_3934|M.smegmatis_MC2_155      --------------MSDRYVRTLDILTIADAEEAGGKGANLGELVA----
MMAR_3410|M.marinum_M               ----------------FSYVRFFEEFGIEDVPLVGGKNASLGEMFQKLSQ
Mvan_4106|M.vanbaalenii_PYR-1       ----------------SEYVRFFEDFGIEDVPLVGGKNASLGEMIQNLSA
                                                       :  :           *.*. .:. :      

Mb1158c|M.bovis_AF2122/97           HHLPVPPAFCITTEVGVRYLAAPESTIAAIWDDVLDRMSWLETETSCTFG
Rv1127c|M.tuberculosis_H37Rv        HHLPVPPAFCITTEVGVRYLAAPGSTIAAIWDDVLDRMSWLETETSCTFG
MUL_0141|M.ulcerans_Agy99           NNLPVPPAFCITSEVGVRYLADPAPTLDAIWDDVVDRIRWLEAETGRTFG
MLBr_00955|M.leprae_Br4923          HQLAVPPAFCITTEVGVRYLAAPTPTMEAIWNDVLDQMRWLEAETSRTFG
MAV_1960|M.avium_104                NGLPVPPAFCITTEICAQWLDDPGTTIDGLSETLTQMIHCLEEQTSRTFG
Mflv_4990|M.gilvum_PYR-GCK          AKLPVPPGFVLLRDCYRDSMRAGG-VDAELASLHREALDDVADTARLGEL
TH_1154|M.thermoresistible__bu      AALPVPPGFVLLRDCYLESMQAGG-VRSELAALHDEALAKVPDTEQLPAL
MSMEG_3934|M.smegmatis_MC2_155      ADLPVPHGFVVMRSAYLDSVRMGG-VEAELAALHTEALTHAADTARLSEL
MMAR_3410|M.marinum_M               QGVRVPHGFATTADAYKHMLDRAG-AWDALHAELDD--LDADDVTALARK
Mvan_4106|M.vanbaalenii_PYR-1       QGVRVPHGFAITAAAYRHMLDEAG-AWERLHAELDD--LDPDDVAALARK
                                      : ** .*          :     .   :     :              

Mb1158c|M.bovis_AF2122/97           RGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPG----AADF
Rv1127c|M.tuberculosis_H37Rv        RGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPG----AADF
MUL_0141|M.ulcerans_Agy99           SGPHPLLVSVRSGANQSMPGMMDTILDLGMNDTVEQALASPG----TGDF
MLBr_00955|M.leprae_Br4923          WGPRPLLVSIRSGAVQSMPGMMDTILNLGINDPVEQALAAASPSPIPQTF
MAV_1960|M.avium_104                RGPRPLLVSVRSGAALSMPGMMDTVLNLGMNDTVEQALAQTF----SARF
Mflv_4990|M.gilvum_PYR-GCK          CERMQGLVRKAGVDDATAADMLAAYHAM----GPGAVVAVRS----SATG
TH_1154|M.thermoresistible__bu      CERLQSLVRKAGMADEVRKSVLAAYRRL----GPDAVVAVRS----SATG
MSMEG_3934|M.smegmatis_MC2_155      CRRMQSLVNKAGLSPSVRDATLAAYRAL----GTDVVVAVRS----SATG
MMAR_3410|M.marinum_M               GKRAREIVYGAGLPEDLASEIVAAYRIMQEEYGEDVSLAVRS----SATA
Mvan_4106|M.vanbaalenii_PYR-1       AKRAREIVYGAGLPDDLAAEILDGYRALQREYGEEVSLAVRS----SATA
                                          :*   .         :     :         :*       .   

Mb1158c|M.bovis_AF2122/97           AHDTRRRFTSMYRRIVGS---AGPITDDPYAQLRASIEAVFASWNSPRAV
Rv1127c|M.tuberculosis_H37Rv        AHDTRRRFTSMYRRIVGS---AGPITDDPYAQLRASIEAVFASWNSPRAV
MUL_0141|M.ulcerans_Agy99           ARDTRRRFTRMYRRIVAG---SDPP-DDPYEQLRAGIGAVFASWNSPRAI
MLBr_00955|M.leprae_Br4923          ARDTRLRFIRTYRRIVDP---LNPPPANTYDQLRAAIESIFSSWNSPRAV
MAV_1960|M.avium_104                AMDTRARFADMYRRIVLDGDASAAVPDDPFLQLLGAIEAVFASWNSPRAV
Mflv_4990|M.gilvum_PYR-GCK          EDGADASFAGMNATLTNIT---------GDDGLVTAVTRCWMSLFSPRVI
TH_1154|M.thermoresistible__bu      EDGRDASFAGMNATMTNVA---------GEDALLEAVVRCWMSLFSPRVI
MSMEG_3934|M.smegmatis_MC2_155      EDGRDASFAGMNRTITNVM---------GEVALLDAVTQCWMSLFSPRVI
MMAR_3410|M.marinum_M               EDLPTASFAGQQETFLNIK---------GEESLLDACRRCFASLFTDRAI
Mvan_4106|M.vanbaalenii_PYR-1       EDLPTASFAGQQDSYLNIK---------GEESLLDTCRRCFASLFTDRAI
                                           *                        *       : *  : *.:

Mb1158c|M.bovis_AF2122/97           AYRDHHGLDD-QGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFG
Rv1127c|M.tuberculosis_H37Rv        AYRDHHGLDD-QGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFG
MUL_0141|M.ulcerans_Agy99           AYRNHYSLDD-QGGTAVVVQAMVFGNRSADSGAGVLSSRNPITGASEPFG
MLBr_00955|M.leprae_Br4923          AYRTHYGLDD-QSGTAVIVQAMVFGNQGAYSGAGTLFSRNPITRESKLFG
MAV_1960|M.avium_104                AYRKHHGRDD-LGGTAVVVQAMVFGNMESNSGTGVLFSRNPITGADEPFG
Mflv_4990|M.gilvum_PYR-GCK          TYRASRGFLG-TPAMAVVVQKMIDSEKS-----GVAFTADPSTGARDRVV
TH_1154|M.thermoresistible__bu      TYRASRGFTD-EPAMAVVVQQMIASEKS-----GVAFTADPSSGAQDRVV
MSMEG_3934|M.smegmatis_MC2_155      TYRASRGFTA-APAMAVVVQQMLSADRA-----GVAFTSDPSTGDADHIV
MMAR_3410|M.marinum_M               HYRVDQGFDHFKVALSIGIMKMVRSDLAS---SGVMFTLDTESGFNDVVF
Mvan_4106|M.vanbaalenii_PYR-1       HYRIDQGFDHFKVSLSIGVMKMVRSDIAS---SGVMFSIDTESGFRDAVF
                                     **   .      . :: :  *: .:       *.  : :. :   . . 

Mb1158c|M.bovis_AF2122/97           EWLPGGQGDDVVSGLVAVAPITALRDQ---------QPAVYDQLMAAARS
Rv1127c|M.tuberculosis_H37Rv        EWLPGGQGDDVVSGLVAVAPITALRDQ---------QPAVYDQLMAAARS
MUL_0141|M.ulcerans_Agy99           EWLPGGQGDDVVSGLLKVEPITALRDR---------LPKIYLELLDAARG
MLBr_00955|M.leprae_Br4923          EWLPGGQGDDVVSGLVEVQPITSLRDE---------QPTVYDELVDTAGR
MAV_1960|M.avium_104                EWLSSGQGEDVVSGTFDARPISVLAEE---------QPHVYDELVAAART
Mflv_4990|M.gilvum_PYR-GCK          IEAAFGLGEVVVSGSVEPDTYVVSKET-----MEPIDVRLGNKTFKIVRG
TH_1154|M.thermoresistible__bu      VEAAWGLGEVVVAGQVEPDTYVVAKED-----LGVLDVRIGHKPFKIVRG
MSMEG_3934|M.smegmatis_MC2_155      IEAAFGQGEVVVSGKVEPDTYVIDKRT-----LEVRDVRIGFKAIKIVRG
MMAR_3410|M.marinum_M               VTGAYGLGENVVQGAVDPDEFYVHKPTYQAGHRAVLRRLIGDKAVKMVFV
Mvan_4106|M.vanbaalenii_PYR-1       ITGAYGLGENVVQGAVDPDEFYVHKPTYLAGHRAVLRRLLGDKAVKMILV
                                       . * *: ** * .                       :  : .     

Mb1158c|M.bovis_AF2122/97           LERMAGDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQLHH----EG
Rv1127c|M.tuberculosis_H37Rv        LERMAGDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQLHH----EG
MUL_0141|M.ulcerans_Agy99           LERLAAEVQEVEFTVESGKLWLLQTRSAERSAQAAVRLALQLRG----AG
MLBr_00955|M.leprae_Br4923          LERLGSDVQEIEFTTEDSKLWLLQTRVAERSAQVAVRLALQLWQ----EG
MAV_1960|M.avium_104                LERLGSDVQDIEYTVEEGKLWLLQTRAAKRSAQAAVRLALKLRD----EG
Mflv_4990|M.gilvum_PYR-GCK          EDGSDTV---VQLDDATAASRVLTDEELHSVAELAVATERHNGCPQDTEW
TH_1154|M.thermoresistible__bu      PDGNDQR---VDLPDDQAHARVLDDRELRRIAELAIATEQHNGCPQDTEW
MSMEG_3934|M.smegmatis_MC2_155      DDGADSM---VQLERSQAEARVLDDDALRKIATLAVATETHNGCPQDIEW
MMAR_3410|M.marinum_M               EGGTKQTTRNIPTPKADRAHFCITDEDVLELAGYALAIEQHYGRPMDIEW
Mvan_4106|M.vanbaalenii_PYR-1       EGETKNTTRNIPTPKADRARFCLTDDDALELAGYACAIEAHYGRPMDMEW
                                              :           :        *  *     :         

Mb1158c|M.bovis_AF2122/97           LIDDTETLRRVTPTHIETLLRPSLQPETRLAAP--------LLAKGLPAC
Rv1127c|M.tuberculosis_H37Rv        LIDDTETLRRVTPTHIETLLRPSLQTETRLAAP--------LLAKGLPAC
MUL_0141|M.ulcerans_Agy99           LIDDGETLRRITPTHVETLLLPTLHPDERLAAS--------LLAKGLPAC
MLBr_00955|M.leprae_Br4923          LIDDAEALRRVTPVHVETVLLPVLQPENHLSAT--------LLAKGTPTC
MAV_1960|M.avium_104                LIDDMETLRRVTPAHIETLLMPSLQPETRLAAP--------LLAKGLPAC
Mflv_4990|M.gilvum_PYR-GCK          AI--ADGAAYLVQARPITTLGHTTPPARTEHV---------VLARGLAAA
TH_1154|M.thermoresistible__bu      AID-AAGEAFLVQARPITTLRHAAAPTSEEHV---------TLARGLAAA
MSMEG_3934|M.smegmatis_MC2_155      VI--ADGAVWLVQARPITTLGSAGSTAGDEPS---------VLIRGLPAA
MMAR_3410|M.marinum_M               AKDGLDGKLYIVQARPETAASQRSMTTVETYVLEGSGEQREILTEGRSVG
Mvan_4106|M.vanbaalenii_PYR-1       AKDGLDGKLYIVQARPETVASQHSVTALESYVLDGHG---DILTEGRSVG
                                              :. .:  *       .                * .* .. 

Mb1158c|M.bovis_AF2122/97           PGVVSGTAYTEVDEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEV
Rv1127c|M.tuberculosis_H37Rv        PGVVSGTAYTEVDEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEV
MUL_0141|M.ulcerans_Agy99           PGVAAGLAYTDVDEALDAADRGEQVILVRDHTRPEDVSGMLAAQGIVTEI
MLBr_00955|M.leprae_Br4923          PGVISGKAYTEVDEALDAAESAEQVILVRDHTRPDDVLGMLASQGVVTEV
MAV_1960|M.avium_104                PGVVSGRAVTDVYDAIDAAEDGQDVILVRRSTSPDDVQGMIAALGIVTGI
Mflv_4990|M.gilvum_PYR-GCK          PGIASG-KVRVLQTPDEGHRLQEGEILVAQMTNPDWLPTIRRAAALVTDT
TH_1154|M.thermoresistible__bu      PGLASG-RVRVLRSPEEGSQLQDGEILVAPMTNPDWLPTIRRAAALVTDT
MSMEG_3934|M.smegmatis_MC2_155      PGVASG-RVRVLLAPDDGDKLTDGEILVAPTTNPDWLPTIRRAAALVTET
MMAR_3410|M.marinum_M               EKVASG-VVKRIDDLERLSDFKPGQVLVADTTTPDWEPVMKIAAAIVTNR
Mvan_4106|M.vanbaalenii_PYR-1       EKIASG-AVRRIEHLAQLSEFKPGEVLVADTTTPDWEPVMKTAAAIVTNR
                                      : :*     :             :**   * *:    :  : .:**  

Mb1158c|M.bovis_AF2122/97           GGAASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVD---GYEGEVRQG
Rv1127c|M.tuberculosis_H37Rv        GGAASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVD---GYEGEVRQG
MUL_0141|M.ulcerans_Agy99           GGAASHAAVVSRELGRVAVVGCGDGVAASLAGKRITVD---GYTGEVREG
MLBr_00955|M.leprae_Br4923          GGAASHAAVVSRELSRVAVVGCGQGTAVSLAGKQITVD---GDKGEVRQG
MAV_1960|M.avium_104                GGTTSHAAVVSRELGRPSVVGCGADVTDALAGKLITVD---GTEGEVREG
Mflv_4990|M.gilvum_PYR-GCK          GGMTCHAAIVARELGVPCIVGTRTGTRDLHDGTTVTV---DGARGEVASG
TH_1154|M.thermoresistible__bu      GGMTCHAAIVARELGVPCVVGTRTATRDLHNGTTVTV---DGTHGRVVSG
MSMEG_3934|M.smegmatis_MC2_155      GGMTCHAAIVARELGVPCVVGARSATVALAVGSMVTV---DGTRGEVTTG
MMAR_3410|M.marinum_M               GGRTCHAAIIARELGIPAVVGAGDATTNVPDGQLVTVSCVEGDTGRVYRG
Mvan_4106|M.vanbaalenii_PYR-1       GGRTCHASIIARELGIPAVVGTGDGTTSVPNGAVVTVSCAEGDTGRVYDG
                                    ** :.**::::***.  .:**    .     *  :**    *  *.*  *

Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_1960|M.avium_104                --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          -VTEPAPQMTVSPRSAP--APVTAEVTGTRVYVNLAMPESAETVAAQPVD
TH_1154|M.thermoresistible__bu      RMASPAAAVTLAEPAARPALAAPAEVTATKIYVNLAMPDSAEEVAARGAD
MSMEG_3934|M.smegmatis_MC2_155      RLPETVRTTTTPQEPAP---HITGEATGTKVYVNLAMPDSAEAVAAQDVD
MMAR_3410|M.marinum_M               EVGFHVDRTEVADLARP----------RTEVMVNLGNPDLAFKTSFLPND
Mvan_4106|M.vanbaalenii_PYR-1       AVGFHVDRTEVGDIARP----------RTEIMLNLGNPDLAFKTSFLPND
                                                                                      

Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_1960|M.avium_104                --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          GVGLLRAEFMLTEALGGR-----HPR-----------DLIARGEQNM---
TH_1154|M.thermoresistible__bu      GVGLLRAEFMLTEALGGR-----HPR-----------DLIARGEQND---
MSMEG_3934|M.smegmatis_MC2_155      GVGLLRAEFMLTEALAGR-----HPR-----------DLITKGEQDT---
MMAR_3410|M.marinum_M               GVGLARMEFIVGEYIKVHPLALLHPDKVDDPEARRTIERLTRGYSDGAEF
Mvan_4106|M.vanbaalenii_PYR-1       GVGLARMEFIISEYIKVHPLALLHPERVADSEASRTIARLTQGYADGSEF
                                                                                      

Mb1158c|M.bovis_AF2122/97           ---------------------VLALSAWSESDTPELR-------------
Rv1127c|M.tuberculosis_H37Rv        ---------------------VLALSAWSESDTPELR-------------
MUL_0141|M.ulcerans_Agy99           ---------------------ILAPSAWSEDDTPELR-------------
MLBr_00955|M.leprae_Br4923          ---------------------NLTLSAWSENETPELR-------------
MAV_1960|M.avium_104                ---------------------ILELTAWSEDDSSDLA-------------
Mflv_4990|M.gilvum_PYR-GCK          LVEKMVDSVGRIAAAFSPRPVVYRATDFRSNEFRGLTGGAEYEPVEHNPM
TH_1154|M.thermoresistible__bu      LVQGMVNAVGRIAAAFAPRPVVYRATDFRTNEFRGLAGGDRYEPEEHNPM
MSMEG_3934|M.smegmatis_MC2_155      LVDAMAAAVTRIGTAFAPRPVIYRAMDFRTNEFRGLAGGEQFEPVEHNPM
MMAR_3410|M.marinum_M               FVQRLSEGIGTIAAAFWPKPVVVRMSDFKSNEYASLIGGSGFEPTESNPM
Mvan_4106|M.vanbaalenii_PYR-1       FVERLSEGIGTIAAAFWPKPVVVRMSDFKTNEYASLVGGQSFEPLESNPM
                                                               :  .:   *              

Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_1960|M.avium_104                --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          IGFRGCYRYVK--EPELFALELEALARVRERS--PNVALMIPFVRTRWEL
TH_1154|M.thermoresistible__bu      IGYRGCYRYIK--EPDVFALELQALARVREEN--PNVALMIPFVRTRWEL
MSMEG_3934|M.smegmatis_MC2_155      IGYRGCYRYIK--EPDLFALELSALARAREHT--PNIHLMIPFVRTRWEL
MMAR_3410|M.marinum_M               IGFRGASRYAHPAYAEGFALECRAMQRVRDQMGLTNVVIMLPFVRRVAEA
Mvan_4106|M.vanbaalenii_PYR-1       LGFRGASRYAHPAYAEGFALECRAMRRVRDEMGLTNVIIMLPFVRRVAEA
                                                                                      

Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_1960|M.avium_104                --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          EECLSLVDASPLGR-QRGLHRWVMAEVPSVVHWLPEYIGMGIDGVSIGSN
TH_1154|M.thermoresistible__bu      EECLELVDASPLGR-QRGLRRWVMAEVPSVVHWLPEYVGMGIDGVSIGSN
MSMEG_3934|M.smegmatis_MC2_155      EECLALVDASPLRR-HRNLHRWVMAEVPSVVHWLPEYVGMGIDGVSIGSN
MMAR_3410|M.marinum_M               DLVLETMAEHGLRRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFSIGSN
Mvan_4106|M.vanbaalenii_PYR-1       DLVLQTMADLGLKRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFSIGSN
                                                                                      

Mb1158c|M.bovis_AF2122/97           ELADIAQRISS---------------------------------------
Rv1127c|M.tuberculosis_H37Rv        ELADIAQRISS---------------------------------------
MUL_0141|M.ulcerans_Agy99           DLTTIALKISPLRAHASGDYPKLDDPSEAGVLTAMAAG-----YTDVVSD
MLBr_00955|M.leprae_Br4923          ELADIARRISPLRVHMTEDHTRLDDSSDTAVRLAINTG-----HADVVSA
MAV_1960|M.avium_104                ELTRIALAVSPLRAHTTGDYPPLDAGSDDAVRAALAAG-----HTDVLSS
Mflv_4990|M.gilvum_PYR-GCK          DLTQLLLGVDRDSDVCAELFDESDPAVLHAIRRIVDTANKFGITSSLCGQ
TH_1154|M.thermoresistible__bu      DLTQLMLGVDRDSDICAELFDESDAAVLDAIGRIVGTARRLGITSSLCGQ
MSMEG_3934|M.smegmatis_MC2_155      DLTQLMLGVDRDSETCAELFDESDAAVLDAISRIISTANRLGITSSLCGQ
MMAR_3410|M.marinum_M               DLTQLTLGVDRDSEIVAFDYDERDDGVKEMIRLAVEGCRRNGIHSGLCGQ
Mvan_4106|M.vanbaalenii_PYR-1       DLTQLTLGVDRDSEVVAFDYDERDEGVKEMIRLAVEGCRRNGIHSGLCGQ
                                    :*: :   :.                                        

Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           AP----------LITMLNALRVQDGL------------------------
MLBr_00955|M.leprae_Br4923          TP----------LIVMMTTLRLQDSKDSSAKS------------------
MAV_1960|M.avium_104                TP----------LITMLTAVRLAGTDTRELSR------------------
Mflv_4990|M.gilvum_PYR-GCK          APSTNPAFAEHLVRLGITSVSVNPDAVDATRRVIAAAERRIMLAAARSLP
TH_1154|M.thermoresistible__bu      APSTDPAFAEHLVRMGITSVSVNPDALESARRTVAAAERRILLESARNVQ
MSMEG_3934|M.smegmatis_MC2_155      APSTRPEFAEHLVRMGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHPR
MMAR_3410|M.marinum_M               APSDYPDMAEFLVRAGIDSVSLNPDVVVKTTRQILDLEQQVVPLQ-----
Mvan_4106|M.vanbaalenii_PYR-1       APSDYPDMAEFLVRIGIDSMSLNPDTVVKTTRQVLELERQLASAR-----
                                                                                      

Mb1158c|M.bovis_AF2122/97           -----------
Rv1127c|M.tuberculosis_H37Rv        -----------
MUL_0141|M.ulcerans_Agy99           -----------
MLBr_00955|M.leprae_Br4923          -----------
MAV_1960|M.avium_104                -----------
Mflv_4990|M.gilvum_PYR-GCK          EDQ--------
TH_1154|M.thermoresistible__bu      GDAPADAR---
MSMEG_3934|M.smegmatis_MC2_155      HAPTASPRNPL
MMAR_3410|M.marinum_M               -----------
Mvan_4106|M.vanbaalenii_PYR-1       -----------