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MSSFSYVRFFEEFGIEDVPLVGGKNASLGEMFQKLSQQGVRVPHGFATTADAYKHMLDRAGAWDALHAEL DDLDADDVTALARKGKRAREIVYGAGLPEDLASEIVAAYRIMQEEYGEDVSLAVRSSATAEDLPTASFAG QQETFLNIKGEESLLDACRRCFASLFTDRAIHYRVDQGFDHFKVALSIGIMKMVRSDLASSGVMFTLDTE SGFNDVVFVTGAYGLGENVVQGAVDPDEFYVHKPTYQAGHRAVLRRLIGDKAVKMVFVEGGTKQTTRNIP TPKADRAHFCITDEDVLELAGYALAIEQHYGRPMDIEWAKDGLDGKLYIVQARPETAASQRSMTTVETYV LEGSGEQREILTEGRSVGEKVASGVVKRIDDLERLSDFKPGQVLVADTTTPDWEPVMKIAAAIVTNRGGR TCHAAIIARELGIPAVVGAGDATTNVPDGQLVTVSCVEGDTGRVYRGEVGFHVDRTEVADLARPRTEVMV NLGNPDLAFKTSFLPNDGVGLARMEFIVGEYIKVHPLALLHPDKVDDPEARRTIERLTRGYSDGAEFFVQ RLSEGIGTIAAAFWPKPVVVRMSDFKSNEYASLIGGSGFEPTESNPMIGFRGASRYAHPAYAEGFALECR AMQRVRDQMGLTNVVIMLPFVRRVAEADLVLETMAEHGLRRGENGLKVYAMCEIPNNVILIDQFAKRFDG FSIGSNDLTQLTLGVDRDSEIVAFDYDERDDGVKEMIRLAVEGCRRNGIHSGLCGQAPSDYPDMAEFLVR AGIDSVSLNPDVVVKTTRQILDLEQQVVPLQ
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_3410 | - | - | 100% (801) | pyruvate dikinase |
M. marinum M | MMAR_3024 | - | 5e-13 | 36.08% (158) | hypothetical protein MMAR_3024 |
M. marinum M | MMAR_4331 | ppdK | 3e-10 | 29.65% (199) | pyruvate, phosphate dikinase PpdK |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2073c | - | 9e-13 | 31.87% (182) | hypothetical protein Mb2073c |
M. gilvum PYR-GCK | Mflv_4990 | - | 1e-127 | 39.00% (800) | phosphoenolpyruvate synthase |
M. tuberculosis H37Rv | Rv2047c | - | 9e-13 | 31.87% (182) | hypothetical protein Rv2047c |
M. leprae Br4923 | MLBr_00955 | ppdK | 4e-09 | 30.50% (141) | pyruvate phosphate dikinase |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. avium 104 | MAV_5059 | - | 2e-15 | 24.50% (498) | pyruvate phosphate dikinase |
M. smegmatis MC2 155 | MSMEG_3934 | - | 1e-123 | 38.86% (808) | phosphoenolpyruvate synthase |
M. thermoresistible (build 8) | TH_1154 | - | 1e-129 | 39.36% (808) | phosphoenolpyruvate synthase |
M. ulcerans Agy99 | MUL_2265 | - | 2e-13 | 35.44% (158) | hypothetical protein MUL_2265 |
M. vanbaalenii PYR-1 | Mvan_4106 | - | 0.0 | 84.69% (797) | phosphoenolpyruvate synthase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_3410|M.marinum_M --------------------------------MSS---FSYVR------- Mvan_4106|M.vanbaalenii_PYR-1 --------------------------------MGT---SEYVR------- Mflv_4990|M.gilvum_PYR-GCK --------------------------------MESGTRNTHVC------- TH_1154|M.thermoresistible__bu --------------------------------MDH-VADRFVR------- MSMEG_3934|M.smegmatis_MC2_155 --------------------------------MDI-MSDRYVR------- MLBr_00955|M.leprae_Br4923 MPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAH MAV_5059|M.avium_104 --------------------------------MSAPTDQATER------- Mb2073c|M.bovis_AF2122/97 ---MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPS------- Rv2047c|M.tuberculosis_H37Rv ---MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPS------- MUL_2265|M.ulcerans_Agy99 ---MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPS------- : MMAR_3410|M.marinum_M ---------------------FFEEFGIEDVPLVGGKNASLGEMFQKL-- Mvan_4106|M.vanbaalenii_PYR-1 ---------------------FFEDFGIEDVPLVGGKNASLGEMIQNL-- Mflv_4990|M.gilvum_PYR-GCK ---------------------DISALSIGDAEEAGGKGANMGELVA---- TH_1154|M.thermoresistible__bu ---------------------DIAELRITDAEEAGGKGANMGEMVA---- MSMEG_3934|M.smegmatis_MC2_155 ---------------------TLDILTIADAEEAGGKGANLGELVA---- MLBr_00955|M.leprae_Br4923 DKVDITTSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYNINAMRR---- MAV_5059|M.avium_104 -------------------VQALVGDGQLTRAQAGGKAWSIQHMLS---- Mb2073c|M.bovis_AF2122/97 --------------SADFIAADIRDATAVESAMTGADVVAHCAWVRGR-- Rv2047c|M.tuberculosis_H37Rv --------------SADFIAADIRDATAVESAMTGADVVAHCAWVRGR-- MUL_2265|M.ulcerans_Agy99 --------------QADFVAGDIRDAAAVRRAITGADVVAHCAWARNPGP : *.. MMAR_3410|M.marinum_M ---------SQQGVRVPHGFATTADAYKHMLDRAG--------------- Mvan_4106|M.vanbaalenii_PYR-1 ---------SAQGVRVPHGFAITAAAYRHMLDEAG--------------- Mflv_4990|M.gilvum_PYR-GCK -----------AKLPVPPGFVLLRDCYRDSMRAGG--------------- TH_1154|M.thermoresistible__bu -----------AALPVPPGFVLLRDCYLESMQAGG--------------- MSMEG_3934|M.smegmatis_MC2_155 -----------ADLPVPHGFVVMRSAYLDSVRMGG--------------- MLBr_00955|M.leprae_Br4923 -----------HQLAVPPAFCITTEVGVRYLAAPTP-------------- MAV_5059|M.avium_104 -----------LNIPVPPGFVLTTDVCREYHDRGRV-------------- Mb2073c|M.bovis_AF2122/97 ----NDHINIDGTANVLKAMAETGTGRIVFTSS----------------- Rv2047c|M.tuberculosis_H37Rv ----NDHINIDGTANVLKAMAETGTGRIVFTSS----------------- MUL_2265|M.ulcerans_Agy99 DGRISQQINIDGTRNVLDAMAACGTGRIVFPSSPHVYRPGLPMPATEHGA * .: MMAR_3410|M.marinum_M ---------AWDALHAELDD--LDADDVTALARKGKRAREIVYGAGLPED Mvan_4106|M.vanbaalenii_PYR-1 ---------AWERLHAELDD--LDPDDVAALARKAKRAREIVYGAGLPDD Mflv_4990|M.gilvum_PYR-GCK ---------VDAELASLHREALDDVADTARLGELCERMQGLVRKAGVDDA TH_1154|M.thermoresistible__bu ---------VRSELAALHDEALAKVPDTEQLPALCERLQSLVRKAGMADE MSMEG_3934|M.smegmatis_MC2_155 ---------VEAELAALHTEALTHAADTARLSELCRRMQSLVNKAGLSPS MLBr_00955|M.leprae_Br4923 --------TMEAIWNDVLDQMRWLEAETSRTFGWGPRPLLVSIRSGAVQS MAV_5059|M.avium_104 --------LPAGVTRDIARAMENLESRSGRRFGHVDHPLLVSVRSGAAIS Mb2073c|M.bovis_AF2122/97 --------GHQPRVEQMLADCGLEWVAVRCALIFGRNVDNWVQRLFALPV Rv2047c|M.tuberculosis_H37Rv --------GHQPRVEQMLADCGLEWVAVRCALIFGRNVDNWVQRLFALPV MUL_2265|M.ulcerans_Agy99 VAPASAEGRHKAGVEQMLQESGAQWVAVRSALIVGRNIDNWVRRLFALPA . MMAR_3410|M.marinum_M LA-SEIVAAYRIMQEEYGEDVSLAVRSSATAEDLPTASFAGQQETFLNIK Mvan_4106|M.vanbaalenii_PYR-1 LA-AEILDGYRALQREYGEEVSLAVRSSATAEDLPTASFAGQQDSYLNIK Mflv_4990|M.gilvum_PYR-GCK TA-ADMLAAYHAM----GPGAVVAVRSSATGEDGADASFAGMNATLTNIT TH_1154|M.thermoresistible__bu VR-KSVLAAYRRL----GPDAVVAVRSSATGEDGRDASFAGMNATMTNVA MSMEG_3934|M.smegmatis_MC2_155 VR-DATLAAYRAL----GTDVVVAVRSSATGEDGRDASFAGMNRTITNVM MLBr_00955|M.leprae_Br4923 MP-GMMDTILNLGINDPVEQALAAASPSPIPQTFARDTRLRFIRTYRRIV MAV_5059|M.avium_104 MP-GMMDTILNLGMNSSIEEALAAETG---DARYAADTRHRFTEQFTRVV Mb2073c|M.bovis_AF2122/97 LPAGYADRVVQVVHSDDAQRLLVRALLDTVIDSGPVNLAAPGELTFRRIA Rv2047c|M.tuberculosis_H37Rv LPAGYADRVVQVVHSDDAQRLLVRALLDTVIDSGPVNLAAPGELTFRRIA MUL_2265|M.ulcerans_Agy99 FPDGSADDVLQVVHLDDVLRLLTRAVSDVGAGTGPVNLAAPGLPTLREIA . .: MMAR_3410|M.marinum_M GE---------ESLLDACRRCFASLFTDRAIHYRVDQGFDHFKVALSIGI Mvan_4106|M.vanbaalenii_PYR-1 GE---------ESLLDTCRRCFASLFTDRAIHYRIDQGFDHFKVSLSIGV Mflv_4990|M.gilvum_PYR-GCK GD---------DGLVTAVTRCWMSLFSPRVITYRASRGFLG-TPAMAVVV TH_1154|M.thermoresistible__bu GE---------DALLEAVVRCWMSLFSPRVITYRASRGFTD-EPAMAVVV MSMEG_3934|M.smegmatis_MC2_155 GE---------VALLDAVTQCWMSLFSPRVITYRASRGFTA-APAMAVVV MLBr_00955|M.leprae_Br4923 DPLNPPPANTYDQLRAAIESIFSSWNSPRAVAYRTHYGLDD-QSGTAVIV MAV_5059|M.avium_104 G--VEPPENHWEQLDLAIRAVLESWNSKRALAYRRSHGIPD-DGGTAVTV Mb2073c|M.bovis_AF2122/97 AALGRPMVPIGSPVLRRVTSFAELELLHSAPLMDVTLLRDRWGFQPAWNA Rv2047c|M.tuberculosis_H37Rv AALGRPMVPIGSPVLRRVTSFAELELLHSAPLMDVTLLRDRWGFQPAWNA MUL_2265|M.ulcerans_Agy99 TALRRPILPVG-AALRRIGSVAEFQLVQGVPVMDTARLHDEWKFQPAFTA . : MMAR_3410|M.marinum_M MKMVRS------DLASSGVMFTLDTESGFNDVVFVTGAYGLGENVVQGAV Mvan_4106|M.vanbaalenii_PYR-1 MKMVRS------DIASSGVMFSIDTESGFRDAVFITGAYGLGENVVQGAV Mflv_4990|M.gilvum_PYR-GCK QKMIDS------EKS--GVAFTADPSTGARDRVVIEAAFGLGEVVVSGSV TH_1154|M.thermoresistible__bu QQMIAS------EKS--GVAFTADPSSGAQDRVVVEAAWGLGEVVVAGQV MSMEG_3934|M.smegmatis_MC2_155 QQMLSA------DRA--GVAFTSDPSTGDADHIVIEAAFGQGEVVVSGKV MLBr_00955|M.leprae_Br4923 QAMVFGN---QGAYSGAGTLFSRNPITRESKLFGEWLPGGQGDDVVSGLV MAV_5059|M.avium_104 QAMVFGN---LDDRSGTGVLFSRDPLSGAAQPYGEWLPRGQGEDVVSGRK Mb2073c|M.bovis_AF2122/97 EECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLA Rv2047c|M.tuberculosis_H37Rv EECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLA MUL_2265|M.ulcerans_Agy99 EESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRLA : * . : *. MMAR_3410|M.marinum_M DPDEFYVHKPTYQAGHRAVLRRLIGDKAVKMVFVEGGTKQTTRNIPTPKA Mvan_4106|M.vanbaalenii_PYR-1 DPDEFYVHKPTYLAGHRAVLRRLLGDKAVKMILVEGETKNTTRNIPTPKA Mflv_4990|M.gilvum_PYR-GCK EPDTYVVSKET-----MEPIDVRLGNKTFKIVRGEDGSDTV---VQLDDA TH_1154|M.thermoresistible__bu EPDTYVVAKED-----LGVLDVRIGHKPFKIVRGPDGNDQR---VDLPDD MSMEG_3934|M.smegmatis_MC2_155 EPDTYVIDKRT-----LEVRDVRIGFKAIKIVRGDDGADSM---VQLERS MLBr_00955|M.leprae_Br4923 EVQPITSLRDE-----QPTVYDELVDTAGRLER--LGSDVQEIEFTTEDS MAV_5059|M.avium_104 DALHLDHLAAT-----MPSVHRDLLAAAATLER--HGRDMQDIEFTVQSG Mb2073c|M.bovis_AF2122/97 GPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGV Rv2047c|M.tuberculosis_H37Rv GPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGV MUL_2265|M.ulcerans_Agy99 GPEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGV . . . MMAR_3410|M.marinum_M DRAHFCITDEDVLELAGYALAIEQHYGRPMDIEWAKDGLDGKLYIVQARP Mvan_4106|M.vanbaalenii_PYR-1 DRARFCLTDDDALELAGYACAIEAHYGRPMDMEWAKDGLDGKLYIVQARP Mflv_4990|M.gilvum_PYR-GCK TAASRVLTDEELHSVAELAVATERHNGCPQDTEWAI--ADGAAYLVQARP TH_1154|M.thermoresistible__bu QAHARVLDDRELRRIAELAIATEQHNGCPQDTEWAID-AAGEAFLVQARP MSMEG_3934|M.smegmatis_MC2_155 QAEARVLDDDALRKIATLAVATETHNGCPQDIEWVI--ADGAVWLVQARP MLBr_00955|M.leprae_Br4923 KLWLLQTRVAERSAQVAVRLALQLWQEGLIDDAEALRRVTPVHVETVLLP MAV_5059|M.avium_104 KLWLLQSRAAKRSPQAALRCAVQLQREGVISTKEALDRLTAEHVRALQRP Mb2073c|M.bovis_AF2122/97 GIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATI Rv2047c|M.tuberculosis_H37Rv GIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATI MUL_2265|M.ulcerans_Agy99 GIAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAMI . . MMAR_3410|M.marinum_M ETAASQRSMTTVETYVLEGSGEQREILTEGRSVGEKVASG-VVKRIDDL- Mvan_4106|M.vanbaalenii_PYR-1 ETVASQHSVTALESYVLDGHG---DILTEGRSVGEKIASG-AVRRIEHL- Mflv_4990|M.gilvum_PYR-GCK ITTLGHTTPPARTEHV---------VLARGLAAAPGIASG-KVRVLQTP- TH_1154|M.thermoresistible__bu ITTLRHAAAPTSEEHV---------TLARGLAAAPGLASG-RVRVLRSP- MSMEG_3934|M.smegmatis_MC2_155 ITTLGSAGSTAGDEPS---------VLIRGLPAAPGVASG-RVRVLLAP- MLBr_00955|M.leprae_Br4923 VLQPENHLSAT--------------LLAKGTPTCPGVISGKAYTEVDEA- MAV_5059|M.avium_104 TLDPAAVAASP--------------PVASGKPASPGIATGLVVIDADEA- Mb2073c|M.bovis_AF2122/97 VSNSGFFGPSMASLP----------IFGAQRPPSESSRARRWLRTLRNIG Rv2047c|M.tuberculosis_H37Rv VSNSGFFGPSMASLP----------IFGAQRPPSESSRARRWLRTLRNIG MUL_2265|M.ulcerans_Agy99 VSNSGFFGPSMGSLP----------IFGEERPPAESSFVRRQLCTVRNIG . . . MMAR_3410|M.marinum_M ---ERLSDFKPGQVLVADTTTPDWEPVMKIAAAIVTNRGGRTCHAAIIAR Mvan_4106|M.vanbaalenii_PYR-1 ---AQLSEFKPGEVLVADTTTPDWEPVMKTAAAIVTNRGGRTCHASIIAR Mflv_4990|M.gilvum_PYR-GCK ---DEGHRLQEGEILVAQMTNPDWLPTIRRAAALVTDTGGMTCHAAIVAR TH_1154|M.thermoresistible__bu ---EEGSQLQDGEILVAPMTNPDWLPTIRRAAALVTDTGGMTCHAAIVAR MSMEG_3934|M.smegmatis_MC2_155 ---DDGDKLTDGEILVAPTTNPDWLPTIRRAAALVTETGGMTCHAAIVAR MLBr_00955|M.leprae_Br4923 ---LDAAESAEQVILVRDHTRPDDVLGMLASQGVVTEVGGAASHAAVVSR MAV_5059|M.avium_104 ---EDLADKGRAVILARPTTDPDDVAAMSASVAVVTELGGSTSHAAVVCR Mb2073c|M.bovis_AF2122/97 VFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLA Rv2047c|M.tuberculosis_H37Rv VFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLA MUL_2265|M.ulcerans_Agy99 VFGVNLVGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLA .* : :: .. : :: MMAR_3410|M.marinum_M ELGIPAVVGAGDATTNVPDGQLVTVSCVEGDTGRVYRGEVGFHVDRTEVA Mvan_4106|M.vanbaalenii_PYR-1 ELGIPAVVGTGDGTTSVPNGAVVTVSCAEGDTGRVYDGAVGFHVDRTEVG Mflv_4990|M.gilvum_PYR-GCK ELGVPCIVGTRTGTRDLHDGTTVTV---DGARGEVASG-VTEPAPQMTVS TH_1154|M.thermoresistible__bu ELGVPCVVGTRTATRDLHNGTTVTV---DGTHGRVVSGRMASPAAAVTLA MSMEG_3934|M.smegmatis_MC2_155 ELGVPCVVGARSATVALAVGSMVTV---DGTRGEVTTGRLPETVRTTTTP MLBr_00955|M.leprae_Br4923 ELSRVAVVGCGQGTAVSLAGKQITV---DGDKGEVRQGNLTLSAWSENET MAV_5059|M.avium_104 EMAVPCVVGCGMDSVTALAGRVVTV---DADTGTVHLGELPVRPLLEADD Mb2073c|M.bovis_AF2122/97 RDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAV Rv2047c|M.tuberculosis_H37Rv RDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAV MUL_2265|M.ulcerans_Agy99 RDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAV . : . : : . * MMAR_3410|M.marinum_M DLARP----------RTEVMVNLGNPDLAFKTSFLPNDGVGLARMEFIVG Mvan_4106|M.vanbaalenii_PYR-1 DIARP----------RTEIMLNLGNPDLAFKTSFLPNDGVGLARMEFIIS Mflv_4990|M.gilvum_PYR-GCK PRSAP--APVTAEVTGTRVYVNLAMPESAETVAAQPVDGVGLLRAEFMLT TH_1154|M.thermoresistible__bu EPAARPALAAPAEVTATKIYVNLAMPDSAEEVAARGADGVGLLRAEFMLT MSMEG_3934|M.smegmatis_MC2_155 QEPAP---HITGEATGTKVYVNLAMPDSAEAVAAQDVDGVGLLRAEFMLT MLBr_00955|M.leprae_Br4923 PELRE----------LADIARRISPLRVHMTEDHTRLDDSSDTAVRLAIN MAV_5059|M.avium_104 EDLRT----------IERWLR----------DDLENYDPSYD-------- Mb2073c|M.bovis_AF2122/97 QRLVA---AARRDPVVIRLLAEPGERLDKLAVEAPEFHSAVLAELTLIGH Rv2047c|M.tuberculosis_H37Rv QRLVA---AARRDPVVIRLLAEPGERLDKLAVEAPEFHSAVLAELTLIGH MUL_2265|M.ulcerans_Agy99 QRLVD---AARHDEAVIRLLSEPGDRLGKLAVAAPHFYDAVRQELSLIGH MMAR_3410|M.marinum_M EYIKVHPLALLHPDKVDDPEARRTIERLTRGYSDGAEFFVQRLSEGIGTI Mvan_4106|M.vanbaalenii_PYR-1 EYIKVHPLALLHPERVADSEASRTIARLTQGYADGSEFFVERLSEGIGTI Mflv_4990|M.gilvum_PYR-GCK EALGGR-----HPR-----------DLIARGEQNM---LVEKMVDSVGRI TH_1154|M.thermoresistible__bu EALGGR-----HPR-----------DLIARGEQND---LVQGMVNAVGRI MSMEG_3934|M.smegmatis_MC2_155 EALAGR-----HPR-----------DLITKGEQDT---LVDAMAAAVTRI MLBr_00955|M.leprae_Br4923 TGHADV-------------------------------------------- MAV_5059|M.avium_104 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 RGPAEV-------------------EMAATSYADNPELLVRMVAKTLRAV Rv2047c|M.tuberculosis_H37Rv RGPAEV-------------------EMAATSYADNPELLVRMVAKTLRAV MUL_2265|M.ulcerans_Agy99 RGPAEV-------------------EMMSTSYADNPELLVGMVAKTLSTS MMAR_3410|M.marinum_M AAAFWPKPVVVRMSD-FKSNEYASLIGGSGFEPTESNPMIGFRGASRYAH Mvan_4106|M.vanbaalenii_PYR-1 AAAFWPKPVVVRMSD-FKTNEYASLVGGQSFEPLESNPMLGFRGASRYAH Mflv_4990|M.gilvum_PYR-GCK AAAFSPRPVVYRATD-FRSNEFRGLTGGAEYEPVEHNPMIGFRGCYRYVK TH_1154|M.thermoresistible__bu AAAFAPRPVVYRATD-FRTNEFRGLAGGDRYEPEEHNPMIGYRGCYRYIK MSMEG_3934|M.smegmatis_MC2_155 GTAFAPRPVIYRAMD-FRTNEFRGLAGGEQFEPVEHNPMIGYRGCYRYIK MLBr_00955|M.leprae_Br4923 ---VSATPLIVMMTT-LRLQDSKDSSAKS--------------------- MAV_5059|M.avium_104 ---------VVALIE-RRQQRGATR------------------------- Mb2073c|M.bovis_AF2122/97 PAPQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYG Rv2047c|M.tuberculosis_H37Rv PAPQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYG MUL_2265|M.ulcerans_Agy99 SVPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHG : MMAR_3410|M.marinum_M P--AYAEGFALECRAMQRVRDQMGLTNVVIMLPFVRRVAEADLVLETMAE Mvan_4106|M.vanbaalenii_PYR-1 P--AYAEGFALECRAMRRVRDEMGLTNVIIMLPFVRRVAEADLVLQTMAD Mflv_4990|M.gilvum_PYR-GCK ----EPELFALELEALARVRERS--PNVALMIPFVRTRWELEECLSLVDA TH_1154|M.thermoresistible__bu ----EPDVFALELQALARVREEN--PNVALMIPFVRTRWELEECLELVDA MSMEG_3934|M.smegmatis_MC2_155 ----EPDLFALELSALARAREHT--PNIHLMIPFVRTRWELEECLALVDA MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_5059|M.avium_104 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 RRLTEAGVFDTPDDVFYLLVDEIDALPADVSGLVARRRAEQRRLAGIVPP Rv2047c|M.tuberculosis_H37Rv RRLTEAGVFDTPDDVFYLLVDEIDALPADVSGLVARRRAEQRRLAGIVPP MUL_2265|M.ulcerans_Agy99 RRLAEAGVLHASDDVFYLLVDEVDALPADVAELVARRRAEQRRLTAVVPP MMAR_3410|M.marinum_M HGLRRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFS--IGSNDLTQLTL Mvan_4106|M.vanbaalenii_PYR-1 LGLKRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFS--IGSNDLTQLTL Mflv_4990|M.gilvum_PYR-GCK SPLGR-QRGLHRWVMAEVPSVVHWLPEYIGMGIDGVS--IGSNDLTQLLL TH_1154|M.thermoresistible__bu SPLGR-QRGLRRWVMAEVPSVVHWLPEYVGMGIDGVS--IGSNDLTQLML MSMEG_3934|M.smegmatis_MC2_155 SPLRR-HRNLHRWVMAEVPSVVHWLPEYVGMGIDGVS--IGSNDLTQLML MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_5059|M.avium_104 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 TVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVRPETIDDLQP Rv2047c|M.tuberculosis_H37Rv TVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVRPETIDDLQP MUL_2265|M.ulcerans_Agy99 TVFSGKWEPSTASAAALTAEGTLRGVGVCGGRVRGRVRIVRPETIDELEP MMAR_3410|M.marinum_M GVDRDSEIVAFDYDERDDGVKEMIRLAVEGCRRNGIHSGLCGQAPSDYPD Mvan_4106|M.vanbaalenii_PYR-1 GVDRDSEVVAFDYDERDEGVKEMIRLAVEGCRRNGIHSGLCGQAPSDYPD Mflv_4990|M.gilvum_PYR-GCK GVDRDSDVCAELFDESDPAVLHAIRRIVDTANKFGITSSLCGQAPSTNPA TH_1154|M.thermoresistible__bu GVDRDSDICAELFDESDAAVLDAIGRIVGTARRLGITSSLCGQAPSTDPA MSMEG_3934|M.smegmatis_MC2_155 GVDRDSETCAELFDESDAAVLDAISRIISTANRLGITSSLCGQAPSTRPE MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_5059|M.avium_104 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 GEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQ Rv2047c|M.tuberculosis_H37Rv GEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQ MUL_2265|M.ulcerans_Agy99 GEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQ MMAR_3410|M.marinum_M MAEFLVRAGIDSVSLNPDVVVKTTRQILDLEQQVVPLQ------------ Mvan_4106|M.vanbaalenii_PYR-1 MAEFLVRIGIDSMSLNPDTVVKTTRQVLELERQLASAR------------ Mflv_4990|M.gilvum_PYR-GCK FAEHLVRLGITSVSVNPDAVDATRRVIAAAERRIMLAAARSLPEDQ---- TH_1154|M.thermoresistible__bu FAEHLVRMGITSVSVNPDALESARRTVAAAERRILLESARNVQGDAPADA MSMEG_3934|M.smegmatis_MC2_155 FAEHLVRMGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHPRHAPTASP MLBr_00955|M.leprae_Br4923 -------------------------------------------------- MAV_5059|M.avium_104 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 GATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR--------- Rv2047c|M.tuberculosis_H37Rv GATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR--------- MUL_2265|M.ulcerans_Agy99 GATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPADLA------- MMAR_3410|M.marinum_M ---- Mvan_4106|M.vanbaalenii_PYR-1 ---- Mflv_4990|M.gilvum_PYR-GCK ---- TH_1154|M.thermoresistible__bu R--- MSMEG_3934|M.smegmatis_MC2_155 RNPL MLBr_00955|M.leprae_Br4923 ---- MAV_5059|M.avium_104 ---- Mb2073c|M.bovis_AF2122/97 ---- Rv2047c|M.tuberculosis_H37Rv ---- MUL_2265|M.ulcerans_Agy99 ----