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M. marinum M MMAR_3410 (-)

annotation: pyruvate dikinase
coordinates: 4207227 - 4209632
length: 801

MSSFSYVRFFEEFGIEDVPLVGGKNASLGEMFQKLSQQGVRVPHGFATTADAYKHMLDRAGAWDALHAEL
DDLDADDVTALARKGKRAREIVYGAGLPEDLASEIVAAYRIMQEEYGEDVSLAVRSSATAEDLPTASFAG
QQETFLNIKGEESLLDACRRCFASLFTDRAIHYRVDQGFDHFKVALSIGIMKMVRSDLASSGVMFTLDTE
SGFNDVVFVTGAYGLGENVVQGAVDPDEFYVHKPTYQAGHRAVLRRLIGDKAVKMVFVEGGTKQTTRNIP
TPKADRAHFCITDEDVLELAGYALAIEQHYGRPMDIEWAKDGLDGKLYIVQARPETAASQRSMTTVETYV
LEGSGEQREILTEGRSVGEKVASGVVKRIDDLERLSDFKPGQVLVADTTTPDWEPVMKIAAAIVTNRGGR
TCHAAIIARELGIPAVVGAGDATTNVPDGQLVTVSCVEGDTGRVYRGEVGFHVDRTEVADLARPRTEVMV
NLGNPDLAFKTSFLPNDGVGLARMEFIVGEYIKVHPLALLHPDKVDDPEARRTIERLTRGYSDGAEFFVQ
RLSEGIGTIAAAFWPKPVVVRMSDFKSNEYASLIGGSGFEPTESNPMIGFRGASRYAHPAYAEGFALECR
AMQRVRDQMGLTNVVIMLPFVRRVAEADLVLETMAEHGLRRGENGLKVYAMCEIPNNVILIDQFAKRFDG
FSIGSNDLTQLTLGVDRDSEIVAFDYDERDDGVKEMIRLAVEGCRRNGIHSGLCGQAPSDYPDMAEFLVR
AGIDSVSLNPDVVVKTTRQILDLEQQVVPLQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3410--100% (801)pyruvate dikinase
M. marinum MMMAR_3024-5e-1336.08% (158) hypothetical protein MMAR_3024
M. marinum MMMAR_4331ppdK3e-1029.65% (199) pyruvate, phosphate dikinase PpdK

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2073c-9e-1331.87% (182) hypothetical protein Mb2073c
M. gilvum PYR-GCKMflv_4990-1e-12739.00% (800) phosphoenolpyruvate synthase
M. tuberculosis H37RvRv2047c-9e-1331.87% (182) hypothetical protein Rv2047c
M. leprae Br4923MLBr_00955ppdK4e-0930.50% (141) pyruvate phosphate dikinase
M. abscessus ATCC 19977-----
M. avium 104MAV_5059-2e-1524.50% (498) pyruvate phosphate dikinase
M. smegmatis MC2 155MSMEG_3934-1e-12338.86% (808) phosphoenolpyruvate synthase
M. thermoresistible (build 8)TH_1154-1e-12939.36% (808) phosphoenolpyruvate synthase
M. ulcerans Agy99MUL_2265-2e-1335.44% (158) hypothetical protein MUL_2265
M. vanbaalenii PYR-1Mvan_4106-0.084.69% (797) phosphoenolpyruvate synthase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3410|M.marinum_M               --------------------------------MSS---FSYVR-------
Mvan_4106|M.vanbaalenii_PYR-1       --------------------------------MGT---SEYVR-------
Mflv_4990|M.gilvum_PYR-GCK          --------------------------------MESGTRNTHVC-------
TH_1154|M.thermoresistible__bu      --------------------------------MDH-VADRFVR-------
MSMEG_3934|M.smegmatis_MC2_155      --------------------------------MDI-MSDRYVR-------
MLBr_00955|M.leprae_Br4923          MPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAH
MAV_5059|M.avium_104                --------------------------------MSAPTDQATER-------
Mb2073c|M.bovis_AF2122/97           ---MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPS-------
Rv2047c|M.tuberculosis_H37Rv        ---MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPS-------
MUL_2265|M.ulcerans_Agy99           ---MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPS-------
                                                                    :                 

MMAR_3410|M.marinum_M               ---------------------FFEEFGIEDVPLVGGKNASLGEMFQKL--
Mvan_4106|M.vanbaalenii_PYR-1       ---------------------FFEDFGIEDVPLVGGKNASLGEMIQNL--
Mflv_4990|M.gilvum_PYR-GCK          ---------------------DISALSIGDAEEAGGKGANMGELVA----
TH_1154|M.thermoresistible__bu      ---------------------DIAELRITDAEEAGGKGANMGEMVA----
MSMEG_3934|M.smegmatis_MC2_155      ---------------------TLDILTIADAEEAGGKGANLGELVA----
MLBr_00955|M.leprae_Br4923          DKVDITTSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYNINAMRR----
MAV_5059|M.avium_104                -------------------VQALVGDGQLTRAQAGGKAWSIQHMLS----
Mb2073c|M.bovis_AF2122/97           --------------SADFIAADIRDATAVESAMTGADVVAHCAWVRGR--
Rv2047c|M.tuberculosis_H37Rv        --------------SADFIAADIRDATAVESAMTGADVVAHCAWVRGR--
MUL_2265|M.ulcerans_Agy99           --------------QADFVAGDIRDAAAVRRAITGADVVAHCAWARNPGP
                                                          :           *..             

MMAR_3410|M.marinum_M               ---------SQQGVRVPHGFATTADAYKHMLDRAG---------------
Mvan_4106|M.vanbaalenii_PYR-1       ---------SAQGVRVPHGFAITAAAYRHMLDEAG---------------
Mflv_4990|M.gilvum_PYR-GCK          -----------AKLPVPPGFVLLRDCYRDSMRAGG---------------
TH_1154|M.thermoresistible__bu      -----------AALPVPPGFVLLRDCYLESMQAGG---------------
MSMEG_3934|M.smegmatis_MC2_155      -----------ADLPVPHGFVVMRSAYLDSVRMGG---------------
MLBr_00955|M.leprae_Br4923          -----------HQLAVPPAFCITTEVGVRYLAAPTP--------------
MAV_5059|M.avium_104                -----------LNIPVPPGFVLTTDVCREYHDRGRV--------------
Mb2073c|M.bovis_AF2122/97           ----NDHINIDGTANVLKAMAETGTGRIVFTSS-----------------
Rv2047c|M.tuberculosis_H37Rv        ----NDHINIDGTANVLKAMAETGTGRIVFTSS-----------------
MUL_2265|M.ulcerans_Agy99           DGRISQQINIDGTRNVLDAMAACGTGRIVFPSSPHVYRPGLPMPATEHGA
                                                   *  .:                              

MMAR_3410|M.marinum_M               ---------AWDALHAELDD--LDADDVTALARKGKRAREIVYGAGLPED
Mvan_4106|M.vanbaalenii_PYR-1       ---------AWERLHAELDD--LDPDDVAALARKAKRAREIVYGAGLPDD
Mflv_4990|M.gilvum_PYR-GCK          ---------VDAELASLHREALDDVADTARLGELCERMQGLVRKAGVDDA
TH_1154|M.thermoresistible__bu      ---------VRSELAALHDEALAKVPDTEQLPALCERLQSLVRKAGMADE
MSMEG_3934|M.smegmatis_MC2_155      ---------VEAELAALHTEALTHAADTARLSELCRRMQSLVNKAGLSPS
MLBr_00955|M.leprae_Br4923          --------TMEAIWNDVLDQMRWLEAETSRTFGWGPRPLLVSIRSGAVQS
MAV_5059|M.avium_104                --------LPAGVTRDIARAMENLESRSGRRFGHVDHPLLVSVRSGAAIS
Mb2073c|M.bovis_AF2122/97           --------GHQPRVEQMLADCGLEWVAVRCALIFGRNVDNWVQRLFALPV
Rv2047c|M.tuberculosis_H37Rv        --------GHQPRVEQMLADCGLEWVAVRCALIFGRNVDNWVQRLFALPV
MUL_2265|M.ulcerans_Agy99           VAPASAEGRHKAGVEQMLQESGAQWVAVRSALIVGRNIDNWVRRLFALPA
                                                                        .             

MMAR_3410|M.marinum_M               LA-SEIVAAYRIMQEEYGEDVSLAVRSSATAEDLPTASFAGQQETFLNIK
Mvan_4106|M.vanbaalenii_PYR-1       LA-AEILDGYRALQREYGEEVSLAVRSSATAEDLPTASFAGQQDSYLNIK
Mflv_4990|M.gilvum_PYR-GCK          TA-ADMLAAYHAM----GPGAVVAVRSSATGEDGADASFAGMNATLTNIT
TH_1154|M.thermoresistible__bu      VR-KSVLAAYRRL----GPDAVVAVRSSATGEDGRDASFAGMNATMTNVA
MSMEG_3934|M.smegmatis_MC2_155      VR-DATLAAYRAL----GTDVVVAVRSSATGEDGRDASFAGMNRTITNVM
MLBr_00955|M.leprae_Br4923          MP-GMMDTILNLGINDPVEQALAAASPSPIPQTFARDTRLRFIRTYRRIV
MAV_5059|M.avium_104                MP-GMMDTILNLGMNSSIEEALAAETG---DARYAADTRHRFTEQFTRVV
Mb2073c|M.bovis_AF2122/97           LPAGYADRVVQVVHSDDAQRLLVRALLDTVIDSGPVNLAAPGELTFRRIA
Rv2047c|M.tuberculosis_H37Rv        LPAGYADRVVQVVHSDDAQRLLVRALLDTVIDSGPVNLAAPGELTFRRIA
MUL_2265|M.ulcerans_Agy99           FPDGSADDVLQVVHLDDVLRLLTRAVSDVGAGTGPVNLAAPGLPTLREIA
                                              .                                    .: 

MMAR_3410|M.marinum_M               GE---------ESLLDACRRCFASLFTDRAIHYRVDQGFDHFKVALSIGI
Mvan_4106|M.vanbaalenii_PYR-1       GE---------ESLLDTCRRCFASLFTDRAIHYRIDQGFDHFKVSLSIGV
Mflv_4990|M.gilvum_PYR-GCK          GD---------DGLVTAVTRCWMSLFSPRVITYRASRGFLG-TPAMAVVV
TH_1154|M.thermoresistible__bu      GE---------DALLEAVVRCWMSLFSPRVITYRASRGFTD-EPAMAVVV
MSMEG_3934|M.smegmatis_MC2_155      GE---------VALLDAVTQCWMSLFSPRVITYRASRGFTA-APAMAVVV
MLBr_00955|M.leprae_Br4923          DPLNPPPANTYDQLRAAIESIFSSWNSPRAVAYRTHYGLDD-QSGTAVIV
MAV_5059|M.avium_104                G--VEPPENHWEQLDLAIRAVLESWNSKRALAYRRSHGIPD-DGGTAVTV
Mb2073c|M.bovis_AF2122/97           AALGRPMVPIGSPVLRRVTSFAELELLHSAPLMDVTLLRDRWGFQPAWNA
Rv2047c|M.tuberculosis_H37Rv        AALGRPMVPIGSPVLRRVTSFAELELLHSAPLMDVTLLRDRWGFQPAWNA
MUL_2265|M.ulcerans_Agy99           TALRRPILPVG-AALRRIGSVAEFQLVQGVPVMDTARLHDEWKFQPAFTA
                                                                 .                :   

MMAR_3410|M.marinum_M               MKMVRS------DLASSGVMFTLDTESGFNDVVFVTGAYGLGENVVQGAV
Mvan_4106|M.vanbaalenii_PYR-1       MKMVRS------DIASSGVMFSIDTESGFRDAVFITGAYGLGENVVQGAV
Mflv_4990|M.gilvum_PYR-GCK          QKMIDS------EKS--GVAFTADPSTGARDRVVIEAAFGLGEVVVSGSV
TH_1154|M.thermoresistible__bu      QQMIAS------EKS--GVAFTADPSSGAQDRVVVEAAWGLGEVVVAGQV
MSMEG_3934|M.smegmatis_MC2_155      QQMLSA------DRA--GVAFTSDPSTGDADHIVIEAAFGQGEVVVSGKV
MLBr_00955|M.leprae_Br4923          QAMVFGN---QGAYSGAGTLFSRNPITRESKLFGEWLPGGQGDDVVSGLV
MAV_5059|M.avium_104                QAMVFGN---LDDRSGTGVLFSRDPLSGAAQPYGEWLPRGQGEDVVSGRK
Mb2073c|M.bovis_AF2122/97           EECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLA
Rv2047c|M.tuberculosis_H37Rv        EECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLA
MUL_2265|M.ulcerans_Agy99           EESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRLA
                                       :             *      .                 : *.    

MMAR_3410|M.marinum_M               DPDEFYVHKPTYQAGHRAVLRRLIGDKAVKMVFVEGGTKQTTRNIPTPKA
Mvan_4106|M.vanbaalenii_PYR-1       DPDEFYVHKPTYLAGHRAVLRRLLGDKAVKMILVEGETKNTTRNIPTPKA
Mflv_4990|M.gilvum_PYR-GCK          EPDTYVVSKET-----MEPIDVRLGNKTFKIVRGEDGSDTV---VQLDDA
TH_1154|M.thermoresistible__bu      EPDTYVVAKED-----LGVLDVRIGHKPFKIVRGPDGNDQR---VDLPDD
MSMEG_3934|M.smegmatis_MC2_155      EPDTYVIDKRT-----LEVRDVRIGFKAIKIVRGDDGADSM---VQLERS
MLBr_00955|M.leprae_Br4923          EVQPITSLRDE-----QPTVYDELVDTAGRLER--LGSDVQEIEFTTEDS
MAV_5059|M.avium_104                DALHLDHLAAT-----MPSVHRDLLAAAATLER--HGRDMQDIEFTVQSG
Mb2073c|M.bovis_AF2122/97           GPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGV
Rv2047c|M.tuberculosis_H37Rv        GPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGV
MUL_2265|M.ulcerans_Agy99           GPEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGV
                                                               .          .     .     

MMAR_3410|M.marinum_M               DRAHFCITDEDVLELAGYALAIEQHYGRPMDIEWAKDGLDGKLYIVQARP
Mvan_4106|M.vanbaalenii_PYR-1       DRARFCLTDDDALELAGYACAIEAHYGRPMDMEWAKDGLDGKLYIVQARP
Mflv_4990|M.gilvum_PYR-GCK          TAASRVLTDEELHSVAELAVATERHNGCPQDTEWAI--ADGAAYLVQARP
TH_1154|M.thermoresistible__bu      QAHARVLDDRELRRIAELAIATEQHNGCPQDTEWAID-AAGEAFLVQARP
MSMEG_3934|M.smegmatis_MC2_155      QAEARVLDDDALRKIATLAVATETHNGCPQDIEWVI--ADGAVWLVQARP
MLBr_00955|M.leprae_Br4923          KLWLLQTRVAERSAQVAVRLALQLWQEGLIDDAEALRRVTPVHVETVLLP
MAV_5059|M.avium_104                KLWLLQSRAAKRSPQAALRCAVQLQREGVISTKEALDRLTAEHVRALQRP
Mb2073c|M.bovis_AF2122/97           GIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATI
Rv2047c|M.tuberculosis_H37Rv        GIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATI
MUL_2265|M.ulcerans_Agy99           GIAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAMI
                                                        .             .               

MMAR_3410|M.marinum_M               ETAASQRSMTTVETYVLEGSGEQREILTEGRSVGEKVASG-VVKRIDDL-
Mvan_4106|M.vanbaalenii_PYR-1       ETVASQHSVTALESYVLDGHG---DILTEGRSVGEKIASG-AVRRIEHL-
Mflv_4990|M.gilvum_PYR-GCK          ITTLGHTTPPARTEHV---------VLARGLAAAPGIASG-KVRVLQTP-
TH_1154|M.thermoresistible__bu      ITTLRHAAAPTSEEHV---------TLARGLAAAPGLASG-RVRVLRSP-
MSMEG_3934|M.smegmatis_MC2_155      ITTLGSAGSTAGDEPS---------VLIRGLPAAPGVASG-RVRVLLAP-
MLBr_00955|M.leprae_Br4923          VLQPENHLSAT--------------LLAKGTPTCPGVISGKAYTEVDEA-
MAV_5059|M.avium_104                TLDPAAVAASP--------------PVASGKPASPGIATGLVVIDADEA-
Mb2073c|M.bovis_AF2122/97           VSNSGFFGPSMASLP----------IFGAQRPPSESSRARRWLRTLRNIG
Rv2047c|M.tuberculosis_H37Rv        VSNSGFFGPSMASLP----------IFGAQRPPSESSRARRWLRTLRNIG
MUL_2265|M.ulcerans_Agy99           VSNSGFFGPSMGSLP----------IFGEERPPAESSFVRRQLCTVRNIG
                                             .                .    .                  

MMAR_3410|M.marinum_M               ---ERLSDFKPGQVLVADTTTPDWEPVMKIAAAIVTNRGGRTCHAAIIAR
Mvan_4106|M.vanbaalenii_PYR-1       ---AQLSEFKPGEVLVADTTTPDWEPVMKTAAAIVTNRGGRTCHASIIAR
Mflv_4990|M.gilvum_PYR-GCK          ---DEGHRLQEGEILVAQMTNPDWLPTIRRAAALVTDTGGMTCHAAIVAR
TH_1154|M.thermoresistible__bu      ---EEGSQLQDGEILVAPMTNPDWLPTIRRAAALVTDTGGMTCHAAIVAR
MSMEG_3934|M.smegmatis_MC2_155      ---DDGDKLTDGEILVAPTTNPDWLPTIRRAAALVTETGGMTCHAAIVAR
MLBr_00955|M.leprae_Br4923          ---LDAAESAEQVILVRDHTRPDDVLGMLASQGVVTEVGGAASHAAVVSR
MAV_5059|M.avium_104                ---EDLADKGRAVILARPTTDPDDVAAMSASVAVVTELGGSTSHAAVVCR
Mb2073c|M.bovis_AF2122/97           VFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLA
Rv2047c|M.tuberculosis_H37Rv        VFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLA
MUL_2265|M.ulcerans_Agy99           VFGVNLVGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLA
                                                         .*       :   ::  ..    : ::  

MMAR_3410|M.marinum_M               ELGIPAVVGAGDATTNVPDGQLVTVSCVEGDTGRVYRGEVGFHVDRTEVA
Mvan_4106|M.vanbaalenii_PYR-1       ELGIPAVVGTGDGTTSVPNGAVVTVSCAEGDTGRVYDGAVGFHVDRTEVG
Mflv_4990|M.gilvum_PYR-GCK          ELGVPCIVGTRTGTRDLHDGTTVTV---DGARGEVASG-VTEPAPQMTVS
TH_1154|M.thermoresistible__bu      ELGVPCVVGTRTATRDLHNGTTVTV---DGTHGRVVSGRMASPAAAVTLA
MSMEG_3934|M.smegmatis_MC2_155      ELGVPCVVGARSATVALAVGSMVTV---DGTRGEVTTGRLPETVRTTTTP
MLBr_00955|M.leprae_Br4923          ELSRVAVVGCGQGTAVSLAGKQITV---DGDKGEVRQGNLTLSAWSENET
MAV_5059|M.avium_104                EMAVPCVVGCGMDSVTALAGRVVTV---DADTGTVHLGELPVRPLLEADD
Mb2073c|M.bovis_AF2122/97           RDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAV
Rv2047c|M.tuberculosis_H37Rv        RDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAV
MUL_2265|M.ulcerans_Agy99           RDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAV
                                    .            :     .  : :    .       *            

MMAR_3410|M.marinum_M               DLARP----------RTEVMVNLGNPDLAFKTSFLPNDGVGLARMEFIVG
Mvan_4106|M.vanbaalenii_PYR-1       DIARP----------RTEIMLNLGNPDLAFKTSFLPNDGVGLARMEFIIS
Mflv_4990|M.gilvum_PYR-GCK          PRSAP--APVTAEVTGTRVYVNLAMPESAETVAAQPVDGVGLLRAEFMLT
TH_1154|M.thermoresistible__bu      EPAARPALAAPAEVTATKIYVNLAMPDSAEEVAARGADGVGLLRAEFMLT
MSMEG_3934|M.smegmatis_MC2_155      QEPAP---HITGEATGTKVYVNLAMPDSAEAVAAQDVDGVGLLRAEFMLT
MLBr_00955|M.leprae_Br4923          PELRE----------LADIARRISPLRVHMTEDHTRLDDSSDTAVRLAIN
MAV_5059|M.avium_104                EDLRT----------IERWLR----------DDLENYDPSYD--------
Mb2073c|M.bovis_AF2122/97           QRLVA---AARRDPVVIRLLAEPGERLDKLAVEAPEFHSAVLAELTLIGH
Rv2047c|M.tuberculosis_H37Rv        QRLVA---AARRDPVVIRLLAEPGERLDKLAVEAPEFHSAVLAELTLIGH
MUL_2265|M.ulcerans_Agy99           QRLVD---AARHDEAVIRLLSEPGDRLGKLAVAAPHFYDAVRQELSLIGH
                                                                                      

MMAR_3410|M.marinum_M               EYIKVHPLALLHPDKVDDPEARRTIERLTRGYSDGAEFFVQRLSEGIGTI
Mvan_4106|M.vanbaalenii_PYR-1       EYIKVHPLALLHPERVADSEASRTIARLTQGYADGSEFFVERLSEGIGTI
Mflv_4990|M.gilvum_PYR-GCK          EALGGR-----HPR-----------DLIARGEQNM---LVEKMVDSVGRI
TH_1154|M.thermoresistible__bu      EALGGR-----HPR-----------DLIARGEQND---LVQGMVNAVGRI
MSMEG_3934|M.smegmatis_MC2_155      EALAGR-----HPR-----------DLITKGEQDT---LVDAMAAAVTRI
MLBr_00955|M.leprae_Br4923          TGHADV--------------------------------------------
MAV_5059|M.avium_104                --------------------------------------------------
Mb2073c|M.bovis_AF2122/97           RGPAEV-------------------EMAATSYADNPELLVRMVAKTLRAV
Rv2047c|M.tuberculosis_H37Rv        RGPAEV-------------------EMAATSYADNPELLVRMVAKTLRAV
MUL_2265|M.ulcerans_Agy99           RGPAEV-------------------EMMSTSYADNPELLVGMVAKTLSTS
                                                                                      

MMAR_3410|M.marinum_M               AAAFWPKPVVVRMSD-FKSNEYASLIGGSGFEPTESNPMIGFRGASRYAH
Mvan_4106|M.vanbaalenii_PYR-1       AAAFWPKPVVVRMSD-FKTNEYASLVGGQSFEPLESNPMLGFRGASRYAH
Mflv_4990|M.gilvum_PYR-GCK          AAAFSPRPVVYRATD-FRSNEFRGLTGGAEYEPVEHNPMIGFRGCYRYVK
TH_1154|M.thermoresistible__bu      AAAFAPRPVVYRATD-FRTNEFRGLAGGDRYEPEEHNPMIGYRGCYRYIK
MSMEG_3934|M.smegmatis_MC2_155      GTAFAPRPVIYRAMD-FRTNEFRGLAGGEQFEPVEHNPMIGYRGCYRYIK
MLBr_00955|M.leprae_Br4923          ---VSATPLIVMMTT-LRLQDSKDSSAKS---------------------
MAV_5059|M.avium_104                ---------VVALIE-RRQQRGATR-------------------------
Mb2073c|M.bovis_AF2122/97           PAPQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYG
Rv2047c|M.tuberculosis_H37Rv        PAPQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYG
MUL_2265|M.ulcerans_Agy99           SVPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHG
                                             :                                        

MMAR_3410|M.marinum_M               P--AYAEGFALECRAMQRVRDQMGLTNVVIMLPFVRRVAEADLVLETMAE
Mvan_4106|M.vanbaalenii_PYR-1       P--AYAEGFALECRAMRRVRDEMGLTNVIIMLPFVRRVAEADLVLQTMAD
Mflv_4990|M.gilvum_PYR-GCK          ----EPELFALELEALARVRERS--PNVALMIPFVRTRWELEECLSLVDA
TH_1154|M.thermoresistible__bu      ----EPDVFALELQALARVREEN--PNVALMIPFVRTRWELEECLELVDA
MSMEG_3934|M.smegmatis_MC2_155      ----EPDLFALELSALARAREHT--PNIHLMIPFVRTRWELEECLALVDA
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_5059|M.avium_104                --------------------------------------------------
Mb2073c|M.bovis_AF2122/97           RRLTEAGVFDTPDDVFYLLVDEIDALPADVSGLVARRRAEQRRLAGIVPP
Rv2047c|M.tuberculosis_H37Rv        RRLTEAGVFDTPDDVFYLLVDEIDALPADVSGLVARRRAEQRRLAGIVPP
MUL_2265|M.ulcerans_Agy99           RRLAEAGVLHASDDVFYLLVDEVDALPADVAELVARRRAEQRRLTAVVPP
                                                                                      

MMAR_3410|M.marinum_M               HGLRRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFS--IGSNDLTQLTL
Mvan_4106|M.vanbaalenii_PYR-1       LGLKRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFS--IGSNDLTQLTL
Mflv_4990|M.gilvum_PYR-GCK          SPLGR-QRGLHRWVMAEVPSVVHWLPEYIGMGIDGVS--IGSNDLTQLLL
TH_1154|M.thermoresistible__bu      SPLGR-QRGLRRWVMAEVPSVVHWLPEYVGMGIDGVS--IGSNDLTQLML
MSMEG_3934|M.smegmatis_MC2_155      SPLRR-HRNLHRWVMAEVPSVVHWLPEYVGMGIDGVS--IGSNDLTQLML
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_5059|M.avium_104                --------------------------------------------------
Mb2073c|M.bovis_AF2122/97           TVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVRPETIDDLQP
Rv2047c|M.tuberculosis_H37Rv        TVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVRPETIDDLQP
MUL_2265|M.ulcerans_Agy99           TVFSGKWEPSTASAAALTAEGTLRGVGVCGGRVRGRVRIVRPETIDELEP
                                                                                      

MMAR_3410|M.marinum_M               GVDRDSEIVAFDYDERDDGVKEMIRLAVEGCRRNGIHSGLCGQAPSDYPD
Mvan_4106|M.vanbaalenii_PYR-1       GVDRDSEVVAFDYDERDEGVKEMIRLAVEGCRRNGIHSGLCGQAPSDYPD
Mflv_4990|M.gilvum_PYR-GCK          GVDRDSDVCAELFDESDPAVLHAIRRIVDTANKFGITSSLCGQAPSTNPA
TH_1154|M.thermoresistible__bu      GVDRDSDICAELFDESDAAVLDAIGRIVGTARRLGITSSLCGQAPSTDPA
MSMEG_3934|M.smegmatis_MC2_155      GVDRDSETCAELFDESDAAVLDAISRIISTANRLGITSSLCGQAPSTRPE
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_5059|M.avium_104                --------------------------------------------------
Mb2073c|M.bovis_AF2122/97           GEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQ
Rv2047c|M.tuberculosis_H37Rv        GEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQ
MUL_2265|M.ulcerans_Agy99           GEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQ
                                                                                      

MMAR_3410|M.marinum_M               MAEFLVRAGIDSVSLNPDVVVKTTRQILDLEQQVVPLQ------------
Mvan_4106|M.vanbaalenii_PYR-1       MAEFLVRIGIDSMSLNPDTVVKTTRQVLELERQLASAR------------
Mflv_4990|M.gilvum_PYR-GCK          FAEHLVRLGITSVSVNPDAVDATRRVIAAAERRIMLAAARSLPEDQ----
TH_1154|M.thermoresistible__bu      FAEHLVRMGITSVSVNPDALESARRTVAAAERRILLESARNVQGDAPADA
MSMEG_3934|M.smegmatis_MC2_155      FAEHLVRMGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHPRHAPTASP
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_5059|M.avium_104                --------------------------------------------------
Mb2073c|M.bovis_AF2122/97           GATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR---------
Rv2047c|M.tuberculosis_H37Rv        GATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR---------
MUL_2265|M.ulcerans_Agy99           GATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPADLA-------
                                                                                      

MMAR_3410|M.marinum_M               ----
Mvan_4106|M.vanbaalenii_PYR-1       ----
Mflv_4990|M.gilvum_PYR-GCK          ----
TH_1154|M.thermoresistible__bu      R---
MSMEG_3934|M.smegmatis_MC2_155      RNPL
MLBr_00955|M.leprae_Br4923          ----
MAV_5059|M.avium_104                ----
Mb2073c|M.bovis_AF2122/97           ----
Rv2047c|M.tuberculosis_H37Rv        ----
MUL_2265|M.ulcerans_Agy99           ----