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MRASPRRGHIDTGRSGRNMGIGCRCTFLSDHRPSVFMKNPTRQTALITAALTAGLLATAATGAAGETRPA AAGADFTPAATPAAPPALAPAPTPNALYAATGSSPILAPTSNVGLQNFATTLAAVPAHRGERGPATHEVG SGPAVDDRATDVRMPGIELLLAAARPNGDRDRAGADSATTADAVNPIAGVIGIFIGNGDEPGENGGLLFG NGADGAPGQNGGRGGLLFGNGGRGGDAVLPGQKGGDGGNAGLIGFGGAGGAGGDHMTSTGGVAAVGGAGG AGGDGGAVFGDGGSGGRGGIANQIGTDPNRFDPAKGGAGGKGGSAGLFGRPGSGGRGGDSHSRTDYAEGG AGGAGGAGVGGAGNGGAGGKGDAYFVAIGGNGGNGGRALLTGAGGDGGDGGTGFSQVSGAHGGDGGDGGG PGGDGGNGGDAGGKDEAYGGWGGDGGPAGVTGDGGKGGNGGNATSASATAYGGRGGNGRDGGLGGDGGAG GDGGTGKSSTGRGDGGNGGNGGNGGLGGRGADGGKGGAGSTNNGKPGGGGNDNGGPPGLAA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3856 | - | - | 100% (551) | hypothetical protein Mvan_3856 |
M. vanbaalenii PYR-1 | Mvan_3867 | - | e-101 | 44.02% (527) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1569 | - | 7e-77 | 46.63% (401) | hypothetical protein Mvan_1569 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1476c | PE_PGRS26 | 5e-82 | 42.08% (480) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_2178 | - | 6e-77 | 39.21% (556) | hypothetical protein Mflv_2178 |
M. tuberculosis H37Rv | Rv2162c | PE_PGRS38 | 6e-83 | 45.13% (421) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 7e-08 | 33.79% (145) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_4284c | - | 8e-36 | 31.47% (502) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_0837 | - | 2e-87 | 42.67% (525) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 2e-21 | 41.94% (186) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_3202 | - | 5e-67 | 34.51% (536) | hypothetical protein MSMEG_3202 |
M. thermoresistible (build 8) | TH_3810 | - | 5e-39 | 38.33% (300) | PUTATIVE - |
M. ulcerans Agy99 | MUL_3292 | - | 3e-80 | 40.62% (544) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0837|M.marinum_M --------------------MSYVIAAPELLAGAATDLAGLGSTLQIANR MUL_3292|M.ulcerans_Agy99 --------------------MSYVIAAPEMLAGAATDLAGIGAALQSANG Rv2162c|M.tuberculosis_H37Rv --------------------MSFVIAAPEVMAAAATDLANIGSSISAASA Mb1476c|M.bovis_AF2122/97 --------------------MSNVMVVPGMLSAAAADVASIGAALSAANG Mflv_2178|M.gilvum_PYR-GCK --------------------MSGTAHAPGKTRLFANVTVAVG--LGGAAL Mvan_3856|M.vanbaalenii_PYR-1 --------------------MRASPRRGHIDTGRSGRNMGIGCRCTFLSD MSMEG_3202|M.smegmatis_MC2_155 ----------------------MTKHQRLTSAVAASIVATAGVAVSQAPA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAE MAV_4827|M.avium_104 -------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAA MLBr_01556|M.leprae_Br4923 ---------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEA MMAR_0837|M.marinum_M AAAA--------------------TITGVPAAGADDVSAALA-AVFSGHA MUL_3292|M.ulcerans_Agy99 AAAA--------------------PITGVLAAGADEISAAVA-ALFSGHA Rv2162c|M.tuberculosis_H37Rv AAAG--------------------PTMGILAAGADEVSVAIS-ALFGSHA Mb1476c|M.bovis_AF2122/97 AAAP--------------------TTAGVLAAGADEVSAAIA-SLFSGYA Mflv_2178|M.gilvum_PYR-GCK GAAA--------------------LLAPQASAAPEEWLPAGP-SSECPPP Mvan_3856|M.vanbaalenii_PYR-1 HRPS--------------------VFMKNPTRQTALITAALT-AGLLATA MSMEG_3202|M.smegmatis_MC2_155 PAST--------------------GTPTAHQTPTSTSTPRWL-TVTSTPE TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSP-SLLSPRD MAV_4827|M.avium_104 TASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARR MLBr_01556|M.leprae_Br4923 PVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVA MMAR_0837|M.marinum_M LDYQALSAQMAGVHQRFVQALTASGS-SYAAAEAANTNPLQGVEEHLLGV MUL_3292|M.ulcerans_Agy99 LDYQALSTQMAGFHQQFVTALNSAGA-SYAAAEAASANPLQAVEQQLLGV Rv2162c|M.tuberculosis_H37Rv QGYQTLSAQLAAYHNQFVRALNAGAG-SYASAEAAN------VQQTLLNA Mb1476c|M.bovis_AF2122/97 RDYQALSAQMARFHQQFVQALTASVG-SYAAAEAANASPLQALEQQVLAA Mflv_2178|M.gilvum_PYR-GCK TDGCANVAAVGGVHG------AQGPA-NLATPQTSG-------------- Mvan_3856|M.vanbaalenii_PYR-1 ATGAAGETRPAAAGADFTPAATPAAPPALAPAPTPNALYAATGSSPILAP MSMEG_3202|M.smegmatis_MC2_155 GAPATPNALYGAILPSTSPGSVTSTGSGIGHREPGIS------GSPAFTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 NDFLSHNDTDFASHNPIASGNQVMSP--SGNVDSFNRGPLLDLSFGDLQF MAV_4827|M.avium_104 IDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS MLBr_01556|M.leprae_Br4923 GNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPL MMAR_0837|M.marinum_M LNSPTQALLGRPLIGDGAAG-----APGQDGGDGG--------------- MUL_3292|M.ulcerans_Agy99 INAPTQALLGRPLIGDGTAG-----APGQNGGDGG--------------- Rv2162c|M.tuberculosis_H37Rv INAPTQTLLGRPLIGNGADG-----GPGQNGGPGG--------------- Mb1476c|M.bovis_AF2122/97 INAPTQTLLGRPLIGNGADG-----LPGQNGGAGG--------------- Mflv_2178|M.gilvum_PYR-GCK ------SPLFRPLFGNGADAPADCVGNACNGRDGG--------------- Mvan_3856|M.vanbaalenii_PYR-1 TSNVGLQNFATTLAAVPAHRGER--GPATHEVGSGPAVDDRATDVRMPGI MSMEG_3202|M.smegmatis_MC2_155 VRAVRPGSSTARLVFAPKTS-----TSGTALTVTP--------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNV MAV_4827|M.avium_104 IPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPL MLBr_01556|M.leprae_Br4923 PGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARP MMAR_0837|M.marinum_M -LLLGNGGAGGTGSAANPDGGNGGAAG----------------------- MUL_3292|M.ulcerans_Agy99 -LLWGNGGAGGVGTAAHPTGGSGGSAG----------------------- Rv2162c|M.tuberculosis_H37Rv -LLYGNGGNGGAGDTANPNGGNGGSAG----------------------- Mb1476c|M.bovis_AF2122/97 -LLWGNGGNGGAGDAAHPNGGNGGDAG----------------------- Mflv_2178|M.gilvum_PYR-GCK -LIWGNGGAG-------ANGGHGGNAG----------------------- Mvan_3856|M.vanbaalenii_PYR-1 ELLLAAARPNGDRDRAGADSATTADAVNPIAGVI---------------- MSMEG_3202|M.smegmatis_MC2_155 -IAVGMVGNAKVTVAVDSSGRPMIGPG----------------------- TH_3810|M.thermoresistible__bu ---------------VDGDGGSGGRTG----------------------- MAB_4284c|M.abscessus_ATCC_199 GVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDR MAV_4827|M.avium_104 KQVLQTTTFLDVSVAEEPETALARGAALAAANAP---------------- MLBr_01556|M.leprae_Br4923 IPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTG-------------VP MMAR_0837|M.marinum_M -------LIGNGGAGGTGYSPTTGSGAVGGNGGAGGTGGWLYGSGGSGGI MUL_3292|M.ulcerans_Agy99 -------LIGTGGAGGAGYGPAAQTGATGGSGGVGGTG----GSGLDGPD Rv2162c|M.tuberculosis_H37Rv -------LIGNGGAGGAG--------AATGAGGAGGNGGWLYGNGGPGGA Mb1476c|M.bovis_AF2122/97 -------MFGNGGAGGAGYSPAAGTGAAGGAGGAGGAGGWLSGNGGAGGN Mflv_2178|M.gilvum_PYR-GCK -------LVGNGGRGGDATTP-------GRSGGHGGNGGRLWGNGGDGGN Mvan_3856|M.vanbaalenii_PYR-1 -----GIFIGNGDEPGENGGLLFGNGADGAPGQNGGRGGLLFGNGGRGGD MSMEG_3202|M.smegmatis_MC2_155 -----GWLIGNGIEPGQNGGLLIGNGADGGPGQKGGNGGFLLGNGGRGGD TH_3810|M.thermoresistible__bu -------LFSKLSRGGDG-----------GDGGLGGNGGHGGGTGIISLL MAB_4284c|M.abscessus_ATCC_199 STNIGSGNTTNTEIGSHNQANIGTSTSAGGSAAVGGNAGLAGNAGLAGNA MAV_4827|M.avium_104 LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGDDELAYSAVGEE MLBr_01556|M.leprae_Br4923 RPGGGRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGG . . . MMAR_0837|M.marinum_M GGVGGSGTIGAPSGHGGSGGLGGGTGLFGQGGAGGNGGQGGGENFASTAG MUL_3292|M.ulcerans_Agy99 SGAAG--------GAGGSGGSGGAARLFGNGGAGGSGGKGGNGGSAIETG Rv2162c|M.tuberculosis_H37Rv AGLGTAG------GVSPAGGAGGAAGLWGHGGAGGAGGSASG-----APG Mb1476c|M.bovis_AF2122/97 GGTGASG------ADGGGGLPPVPASPGGNGGGGGAGG-AAG-----MFG Mflv_2178|M.gilvum_PYR-GCK GAPGVLG-------PAGTAPIPPSSLPAATGTRGDSPPYGYGNLVGGDGG Mvan_3856|M.vanbaalenii_PYR-1 AVLPGQK--------GGDGGNAGLIGFGGAGGAGGDHMTSTGG----VAA MSMEG_3202|M.smegmatis_MC2_155 GLAGVNG---------GRAGDGGNAGLLGNGGDG-------------GNS TH_3810|M.thermoresistible__bu SLAGNGG--------NGGNGYRTTDNNALDGGHGGNGGNVGFFSLFNLGG MAB_4284c|M.abscessus_ATCC_199 GLAGNAG-------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG MAV_4827|M.avium_104 DAESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIG MLBr_01556|M.leprae_Br4923 GRPGQRG------GAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGG . MMAR_0837|M.marinum_M AGGPAGTG-----GHGGWLYGNGGAGGIGGAGGVVGSSEGG---VDGGVG MUL_3292|M.ulcerans_Agy99 NDGAAGAG-----GHGGWLVGNGGIGGDGGSGGVGGDAGAYGPPANGGAG Rv2162c|M.tuberculosis_H37Rv AGGAGGDG-----GRGGLLYGDGGAGGAGGNGSNG---------VTGVHG Mb1476c|M.bovis_AF2122/97 TGGAGGTG-----GDG----GAGGAGDSPNSGANG---------ARGGDG Mflv_2178|M.gilvum_PYR-GCK TGADGGRY-----AFGANWSLDLPVGGAGGAGGWANSIDGS---ATGGNG Mvan_3856|M.vanbaalenii_PYR-1 VGGAGGAG-----GDGGAVFGDGGSGGRGGIANQIGTDPNR---FDPAKG MSMEG_3202|M.smegmatis_MC2_155 VGGVEGAN-----GGNAGLIGNGGKGGDGSPNVISNG-------AHIANA TH_3810|M.thermoresistible__bu AGGWGGSG-----VDGVDVVGGNPDGGTPGAHGESHTPG-----VYTDRQ MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA MAV_4827|M.avium_104 IRTTGTVALQP--TPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAP MLBr_01556|M.leprae_Br4923 VRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVTATQSV . MMAR_0837|M.marinum_M GSGGSGGATG---------------------LLGNGGAGGTGGQGGDGGR MUL_3292|M.ulcerans_Agy99 GHGGMGGVGGDA-----------------GLLFGSGGAGGVGGNGAIGGT Rv2162c|M.tuberculosis_H37Rv GNGGAGGAAG---------------------LIGNGGAGGDGGNGGLSNT Mb1476c|M.bovis_AF2122/97 GNGAAGGAGG--------------------RLFGNGGAGGNGGTAGQGGD Mflv_2178|M.gilvum_PYR-GCK GDGGNGAFGG---------------------RGGNGGAGGSAYGRGGITT Mvan_3856|M.vanbaalenii_PYR-1 GAGGKGGSAG---------------------LFGRPGSGGRGGDSHSRTD MSMEG_3202|M.smegmatis_MC2_155 GRGGNGGNGG--------------------LLVGSGGDGGRGGDGDGEGP TH_3810|M.thermoresistible__bu GEDGEDGTGT-----------------------GIGGRGGNGGSSSGTHP MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAG---------------------LAGNAGLAGNAAVAGNAAV MAV_4827|M.avium_104 KPLSPPVAAP---------------------LPAAPPPAAPPLPEAPPIP MLBr_01556|M.leprae_Br4923 GDETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRP MMAR_0837|M.marinum_M GFDGSLGAGGAGGTGAVGGSGGWLVGDGGTGGDGGQGGGGHLGGAFAGGG MUL_3292|M.ulcerans_Agy99 GVMS--GAGGAGGDGGNGG-YAQLIGDGGGGGAGG-AGYSASGLPPAGIG Rv2162c|M.tuberculosis_H37Rv GASG--GAGGAGG--------AALIGNGGDGGHGGNGGHGNSGG-AGGAG Mb1476c|M.bovis_AF2122/97 GGTA-LGAGGIGG-------------DGGTGGAGGTGGTAGIGGSSAGAG Mflv_2178|M.gilvum_PYR-GCK GGNG--GAGGHGS-------------TGAAGGRGGDGASASGGYAVGGNG Mvan_3856|M.vanbaalenii_PYR-1 YAEG--GAGGAGG-----------AGVGGAGNGGAGGKGDAYFVAIGGNG MSMEG_3202|M.smegmatis_MC2_155 ETAGSHGADGGNG--------------GAGGVFGNGGRGGDGGDANNGTV TH_3810|M.thermoresistible__bu MAED-------------------------------GEHVKALDGRPGLDG MAB_4284c|M.abscessus_ATCC_199 AGNAAVAGNAAVG--------GVLNTGVSGAIGGSSHVGGAINESLGGSG MAV_4827|M.avium_104 AAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPV MLBr_01556|M.leprae_Br4923 PVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSE MMAR_0837|M.marinum_M GDGGAGAVGGTGGWLLGDGGAGGNG------------------GDGGDG- MUL_3292|M.ulcerans_Agy99 APGGAGGAGGSGGWLVGNGGAGGIGGIGASGSFGAP------SGQGGNGG Rv2162c|M.tuberculosis_H37Rv GAGGAGGAGGHVG-LIGNGGNGGAG------------------GNGGND- Mb1476c|M.bovis_AF2122/97 GAGGDGGAGGNGG---GSSMIGGKG------------------------- Mflv_2178|M.gilvum_PYR-GCK GDGGRGGAGATGG----TGGTGGAG------------------GDGGRG- Mvan_3856|M.vanbaalenii_PYR-1 GNGGRALLTGAGG----DGGDGGTG------------------------- MSMEG_3202|M.smegmatis_MC2_155 GTRNGNAAAGKGG----NGGSTGIG------------------------- TH_3810|M.thermoresistible__bu GNGSHGGNGGHGG----RGGFLGIG------------------------- MAB_4284c|M.abscessus_ATCC_199 SVGGSTAVGGGAHTGVGGGVSTGVG----------------------VGS MAV_4827|M.avium_104 RVPQPPSPPQVGGTVPQSPPQHQTP------------------------- MLBr_01556|M.leprae_Br4923 RLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQ MMAR_0837|M.marinum_M -GAASGFAGDGGRGGQGA-VGGASGWLLGNGGAGGDGGAGGEGGDSSG-- MUL_3292|M.ulcerans_Agy99 IGGAAGLFGQGGAGGNGG-QGGGDDFALS-GGAGGAGGAGGHGGQLYGDG Rv2162c|M.tuberculosis_H37Rv ---NSSTLADAGSGGAGA-AGGNGGLFYGNGGVGGRGGNGGFS------- Mb1476c|M.bovis_AF2122/97 --------GTGGNGGVGG-TGGASALTIGNGSSAGAGG------------ Mflv_2178|M.gilvum_PYR-GCK ----GLLGGHGGKGGNAG-LGGNGG-TGGTGGVGGDGGVGG--------- Mvan_3856|M.vanbaalenii_PYR-1 --------FSQVSGAHGG-DGGDGGGPGGDGGNGGDAGGKDE-------- MSMEG_3202|M.smegmatis_MC2_155 ---------TGGAGGNGGKATGTNAAYGGNGGNGGSGLAGGG-------- TH_3810|M.thermoresistible__bu -----------GSGGWGG-HGGNGGDTDADGGNGGDGG------------ MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGISE MAV_4827|M.avium_104 -----PGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVP-------- MLBr_01556|M.leprae_Br4923 AADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKV . * MMAR_0837|M.marinum_M -GAASAGGDGG---------AGGAGGAGANGG--LLIGHGGAG------- MUL_3292|M.ulcerans_Agy99 -GGGGAGGMGGSVDIAESGVTGGRGGSGSVGGGAGLWGAGGQG------- Rv2162c|M.tuberculosis_H37Rv ----SAGTSGG---------DGGIGGAGGIGG---LIGSGGGG------- Mb1476c|M.bovis_AF2122/97 --------------------AGGAGGTGGTGGYIESLDGKGQA------- Mflv_2178|M.gilvum_PYR-GCK -GILTATGVVG---------AGGSGGAGGTGG------RGGDG------- Mvan_3856|M.vanbaalenii_PYR-1 -------------------AYGGWGGDGGPAG---VTGDGGKG------- MSMEG_3202|M.smegmatis_MC2_155 --------------------NGGDGGDAQSSSNRARPGQGGQA------- TH_3810|M.thermoresistible__bu --------------------NGGSAGRGGTGGLRGVFGINGGN------- MAB_4284c|M.abscessus_ATCC_199 -SLGGSGSVGG------STAVGGGAHTGVGGGVNTGVGVGSHV------- MAV_4827|M.avium_104 --------------------TPGAGGSGGSGG--GHVPTPGTG------- MLBr_01556|M.leprae_Br4923 GTNIEALLEAVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLV . . . . MMAR_0837|M.marinum_M -------GGGGTGGNGHG---RPIGSGGAGGDGGGGGTGGWLYGNGGHGG MUL_3292|M.ulcerans_Agy99 -------GDGAQGGDGGAGVDTTTGAGGDGGAGAGGGTSGFLYGNGGAGG Rv2162c|M.tuberculosis_H37Rv -------GDGGNGGQAPT-----PGNAGDGGAGG----NARLIGDGGRGG Mb1476c|M.bovis_AF2122/97 -------GNGGNGGNGAA------GGAGGGGTGAG--------GNGGAGG Mflv_2178|M.gilvum_PYR-GCK -------GDGGQAGRGGAG-----GLAGRSGADGEAG----DAGTGGRGG Mvan_3856|M.vanbaalenii_PYR-1 -------GNGGNATSASAT-----AYGGRGGNGRDGG----LGGDGGAGG MSMEG_3202|M.smegmatis_MC2_155 -------GRGGFGRDGKTG----NPGNATDRSATRENVSNRVTGRSTPTR TH_3810|M.thermoresistible__bu -------GRAGLGGRGXXX--------XGGGVGAAVRSGNGVFSGGGGTP MAB_4284c|M.abscessus_ATCC_199 -------GGGISESLGGSG--SVGGSTAVGGGAHTSAINDALGGSGSVGG MAV_4827|M.avium_104 -------GPGGTGGSGGGH----VPTPGAGTPGGSGGGHLPFPGAGSTPG MLBr_01556|M.leprae_Br4923 QRGTLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPG * . . . . MMAR_0837|M.marinum_M T------------------------------------------------- MUL_3292|M.ulcerans_Agy99 A------------------------------------------------- Rv2162c|M.tuberculosis_H37Rv N------------------------------------------------- Mb1476c|M.bovis_AF2122/97 N------------------------------------------------- Mflv_2178|M.gilvum_PYR-GCK A------------------------------------------------- Mvan_3856|M.vanbaalenii_PYR-1 D------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 S------------------------------------------------- TH_3810|M.thermoresistible__bu S------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 S------------------------------------------------- MAV_4827|M.avium_104 G------------------------------------------------- MLBr_01556|M.leprae_Br4923 AGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETS MMAR_0837|M.marinum_M ------GATGGSG---RHSGASGDGGDGGDAQAIGDGGAGGSG------- MUL_3292|M.ulcerans_Agy99 ------GGHGGGGP--GMGGDGGDGGDGGRAQLIGTGGNGGAGGTAAPGG Rv2162c|M.tuberculosis_H37Rv ------GGEGGDGPP-GVKGDGGNGGNGGNAVVIGNGGNGGAGGFGIP-- Mb1476c|M.bovis_AF2122/97 ------GGDGGPSQ---GGGNPGFGGDGG------TGGPGGVG------- Mflv_2178|M.gilvum_PYR-GCK ------GGSGGKGGI-SGTGTPGGAGQSGQSATGRSGGAGGEG------- Mvan_3856|M.vanbaalenii_PYR-1 ------GGTGKSSTGRGDGGNGGNGGNGGLGGRGADGGKGGAG------- MSMEG_3202|M.smegmatis_MC2_155 ------ADKAGSRTSSSSESNSESNSESSSKTSSKAGGTKSSD------- TH_3810|M.thermoresistible__bu ------AGFGVPTTIQFPAGSCTSRAVSREGIMPSSRAASARAG------ MAB_4284c|M.abscessus_ATCC_199 ------TAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGT MAV_4827|M.avium_104 ------SGGGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGGGGGHAPAPG MLBr_01556|M.leprae_Br4923 QLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLA . MMAR_0837|M.marinum_M --GAGGAGGSGGLLFGAPGAHG---------------------------- MUL_3292|M.ulcerans_Agy99 TDGTAGAAGKGGVLFGTDGATG---------------------------- Rv2162c|M.tuberculosis_H37Rv -VGSGGAGGSRGVLFGTPGANGADG------------------------- Mb1476c|M.bovis_AF2122/97 --VPDGIGGAN----GAQGKHG---------------------------- Mflv_2178|M.gilvum_PYR-GCK --GAGGAGGTDD-------------------------------------- Mvan_3856|M.vanbaalenii_PYR-1 STNNGKPGGGGNDNGGPPGLAA---------------------------- MSMEG_3202|M.smegmatis_MC2_155 TKSGGGAAGTGSDSKDSE-------------------------------- TH_3810|M.thermoresistible__bu -AACASSTSRSRRSFCCSRA------------------------------ MAB_4284c|M.abscessus_ATCC_199 GFEAQGHAQGHASETAHTTLPGAEHH------------------------ MAV_4827|M.avium_104 GGLGGFGGGHSGGGLGGLGGGHK--------------------------- MLBr_01556|M.leprae_Br4923 SASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGML MMAR_0837|M.marinum_M -------------------------------------------------- MUL_3292|M.ulcerans_Agy99 -------------------------------------------------- Rv2162c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3856|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 KPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIV MMAR_0837|M.marinum_M -------------------------------------------------- MUL_3292|M.ulcerans_Agy99 -------------------------------------------------- Rv2162c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1476c|M.bovis_AF2122/97 -------------------------------------------------- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3856|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 VTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQ MMAR_0837|M.marinum_M -- MUL_3292|M.ulcerans_Agy99 -- Rv2162c|M.tuberculosis_H37Rv -- Mb1476c|M.bovis_AF2122/97 -- Mflv_2178|M.gilvum_PYR-GCK -- Mvan_3856|M.vanbaalenii_PYR-1 -- MSMEG_3202|M.smegmatis_MC2_155 -- TH_3810|M.thermoresistible__bu -- MAB_4284c|M.abscessus_ATCC_199 -- MAV_4827|M.avium_104 -- MLBr_01556|M.leprae_Br4923 RA