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MSYVIAAPEMLAGAATDLAGIGAALQSANGAAAAPITGVLAAGADEISAAVAALFSGHALDYQALSTQMA GFHQQFVTALNSAGASYAAAEAASANPLQAVEQQLLGVINAPTQALLGRPLIGDGTAGAPGQNGGDGGLL WGNGGAGGVGTAAHPTGGSGGSAGLIGTGGAGGAGYGPAAQTGATGGSGGVGGTGGSGLDGPDSGAAGGA GGSGGSGGAARLFGNGGAGGSGGKGGNGGSAIETGNDGAAGAGGHGGWLVGNGGIGGDGGSGGVGGDAGA YGPPANGGAGGHGGMGGVGGDAGLLFGSGGAGGVGGNGAIGGTGVMSGAGGAGGDGGNGGYAQLIGDGGG GGAGGAGYSASGLPPAGIGAPGGAGGAGGSGGWLVGNGGAGGIGGIGASGSFGAPSGQGGNGGIGGAAGL FGQGGAGGNGGQGGGDDFALSGGAGGAGGAGGHGGQLYGDGGGGGAGGMGGSVDIAESGVTGGRGGSGSV GGGAGLWGAGGQGGDGAQGGDGGAGVDTTTGAGGDGGAGAGGGTSGFLYGNGGAGGAGGHGGGGPGMGGD GGDGGDGGRAQLIGTGGNGGAGGTAAPGGTDGTAGAAGKGGVLFGTDGATG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3292 | - | - | 100% (611) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_4581 | - | e-165 | 58.10% (580) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_0212 | - | e-156 | 51.27% (669) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 1e-173 | 49.66% (745) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-112 | 47.41% (540) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 1e-172 | 49.47% (748) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-12 | 36.46% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-47 | 31.52% (533) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_2053 | - | 0.0 | 79.65% (737) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 1e-22 | 42.78% (180) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-90 | 39.76% (659) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 7e-42 | 41.44% (292) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-116 | 41.91% (649) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3292|M.ulcerans_Agy99 ----------------------------------MSYVIAAPEMLAGAAT
MMAR_2053|M.marinum_M ----------------------------------MSYVIAAPEMLAGAAT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mb1121|M.bovis_AF2122/97 ----------------------------------MSFVIAAPEALVAVAS
Rv1091|M.tuberculosis_H37Rv ----------------------------------MSFVIAAPEALVAVAS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------MSIIDFILNLFR
MAV_4827|M.avium_104 ------------------------------MNIVLGVSMAPSSIQMVVLE
MUL_3292|M.ulcerans_Agy99 DLAGIGAALQSANGAAAAPITGVLAAGADEISAAVAALFSGHALDYQALS
MMAR_2053|M.marinum_M DLAGIGAALQSANGAAAAPITGVLAAGADDISAAVAALFSGHALDYQALS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mb1121|M.bovis_AF2122/97 DLAGIGSALAEANAAALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVS
Rv1091|M.tuberculosis_H37Rv DLAGIGSALAEANAAALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQW
MAV_4827|M.avium_104 GEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLS
MUL_3292|M.ulcerans_Agy99 --------------------------TQMAGFHQQFVTALNSAGASYAAA
MMAR_2053|M.marinum_M --------------------------TQMAGFHQQFVTALNSAGASYAAA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mb1121|M.bovis_AF2122/97 --------------------------AQASAFHAQFVQALTGGGGAYAAA
Rv1091|M.tuberculosis_H37Rv --------------------------AQASAFHAQFVQALTGGGGAYAAA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VN------------------------------TGNPIHDLSGNLQNYYAA
MAV_4827|M.avium_104 SIG---------------------------VTWTDQLEAAALRDALAARR
MUL_3292|M.ulcerans_Agy99 EAASAN--------------------------------PLQAVEQQLLGV
MMAR_2053|M.marinum_M EAASAN--------------------------------PLQAVEQQLLGV
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mb1121|M.bovis_AF2122/97 EAAN--------------------------------VSAAQSTDQRLLDL
Rv1091|M.tuberculosis_H37Rv EAAN--------------------------------VSAAQSTDQRLLDL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 QPDG-----------------------------------PSILSPSLLSP
MAV_4827|M.avium_104 IDN-------------------------------------VMLVSAFLAA
MUL_3292|M.ulcerans_Agy99 IN--------------------APTQALLG--------------------
MMAR_2053|M.marinum_M IN--------------------APTQALLG--------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mb1121|M.bovis_AF2122/97 IN--------------------GPTQALLG--------RPLIGDGANG-G
Rv1091|M.tuberculosis_H37Rv IN--------------------GPTQALLG--------RPLIGDGANG-G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RD-----------------------------------------NDFLSHN
MAV_4827|M.avium_104 AA------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------RPLIGDG-------TAGAPGQNGGDGGLLWGNGGAGGVGTAA
MMAR_2053|M.marinum_M --------RPLIGDG-------TAGAPGQNGGDGGLLWGNGGAGGVGTAA
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
Mb1121|M.bovis_AF2122/97 PGQDGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIG-NGGAGGGGGAG
Rv1091|M.tuberculosis_H37Rv PGQDGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIG-NGGAGGGGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIG
MAV_4827|M.avium_104 -------LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQ
MUL_3292|M.ulcerans_Agy99 HPTGGSGGSAG---LIGTGGAGGAG---------------YGPAAQTGAT
MMAR_2053|M.marinum_M HPTGGSGGSAG---LIGTGGAGGAG---------------YGPAAQTGAT
TH_3810|M.thermoresistible__bu G-DGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGT
Mflv_5091|M.gilvum_PYR-GCK G-NGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGAT
Mvan_1264|M.vanbaalenii_PYR-1 G-DGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGAT
MSMEG_0868|M.smegmatis_MC2_155 L-DGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGT
Mb1121|M.bovis_AF2122/97 A-AGGNGGAGG--WLYGNGGAGGAGGTSVIP----------GVAGGNGGA
Rv1091|M.tuberculosis_H37Rv A-AGGNGGAGG--WLYGNGGAGGAGGTSVIP----------GVAGGNGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIIN-------ADHGSNVGV
MAV_4827|M.avium_104 IRAESYGDAAGQLSAMVAGLEKLESLPG-------------GLLLVGSGV
MUL_3292|M.ulcerans_Agy99 GGSGGVG----------------------GTGGS----------------
MMAR_2053|M.marinum_M GGSGGVGGTGG------WLYGNGGAGGIGGTGGS----------------
TH_3810|M.thermoresistible__bu GIIS--------------------LLSLAGNGGNGG--------------
Mflv_5091|M.gilvum_PYR-GCK GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 GVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNV
Mb1121|M.bovis_AF2122/97 GGSAGLWGTGG--AGGDGGNGRSGPVNVAGSAGGNGG-------------
Rv1091|M.tuberculosis_H37Rv GGSAGLWGTGG--AGGDGGNGRSGPVNVAGSAGGNGG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTN-----------
MAV_4827|M.avium_104 DVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAAN-------------
MUL_3292|M.ulcerans_Agy99 --GLDGPD-SGAAGGAGG--------------------------------
MMAR_2053|M.marinum_M --GLDGPD-SGAAGGAGG--------------------------------
TH_3810|M.thermoresistible__bu -NGYRTTDNNALDGGHGG--------------------------------
Mflv_5091|M.gilvum_PYR-GCK AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG---------------
Mvan_1264|M.vanbaalenii_PYR-1 AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG---------------
MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG
Mb1121|M.bovis_AF2122/97 AGGAAGLFGDAGAGGNGG--------KGGAGGAAFS--------------
Rv1091|M.tuberculosis_H37Rv AGGAAGLFGDAGAGGNGG--------KGGAGGAAFS--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -INDSFNTDRSTNIGSGN--------------------------------
MAV_4827|M.avium_104 ---APLFASSTAALAYAQ--------------------------------
MUL_3292|M.ulcerans_Agy99 -------------------------------------------SGGSGGA
MMAR_2053|M.marinum_M -------------------------------------------SGGSGGA
TH_3810|M.thermoresistible__bu -------------------------------------------NGGNVGF
Mflv_5091|M.gilvum_PYR-GCK -AVGAAGAAG------TVGTAGATGGTG---------------TGANGGA
Mvan_1264|M.vanbaalenii_PYR-1 -AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGA
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
Mb1121|M.bovis_AF2122/97 -----------------INFTAGDGGAG--------------GAGGSGGH
Rv1091|M.tuberculosis_H37Rv -----------------INFTAGDGGAG--------------GAGGSGGH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------TTNTEIGS
MAV_4827|M.avium_104 --------------------------------------------DPGTGA
MUL_3292|M.ulcerans_Agy99 ARLFGNGGAGGSG--------------GKGGNGGSAIETGNDGAAGAG--
MMAR_2053|M.marinum_M ARLFGNGGAGGSG--------------GQGGNGGSAIETGNGGAAGAGGT
TH_3810|M.thermoresistible__bu FSLFNLGG--------------------AGGWGGSG-VDG----------
Mflv_5091|M.gilvum_PYR-GCK GGVGGVGGTGAAG--------------AAGGAGGLG-ETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 GQAGGIGGTGAAG--------------AAGQAGTAG-ETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDG-IDGGTGGAGGMGE
Mb1121|M.bovis_AF2122/97 ALLWGAGGAGGNG--------------GSGGTGGAGGSTAGAGGNGGAGG
Rv1091|M.tuberculosis_H37Rv ALLWGAGGAGGNG--------------GSGGTGGAGGSTAGAGGNGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HNQANIGTSTSAG--------------GSAAVGGNAGLAGNAGLAGNAGL
MAV_4827|M.avium_104 VDQYSLPDYLYVP--------------VDPEPGDDELAYSAVGEEDAESP
MUL_3292|M.ulcerans_Agy99 ---------------GHGGWLVG---------------------------
MMAR_2053|M.marinum_M G-----------GAGGHGGWLVG---------------------------
TH_3810|M.thermoresistible__bu -----------VDVVGGNP-------------------------------
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
Mb1121|M.bovis_AF2122/97 G-GGTGGLLFGNGGAGGHGAAAGNGLAAGNGVSSSGGGGAG---------
Rv1091|M.tuberculosis_H37Rv G-GGTGGLLFGNGGAGGHGAAAGNGLAAGNGVSSSGGGGAG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AG--------NAGLAGNAGLAGN---------------------------
MAV_4827|M.avium_104 TVVIEKLFLPEDSEPRRRPVLLVG--------------------------
MUL_3292|M.ulcerans_Agy99 -----NGGIGGDGGSGGVGGDAGAYGP-------------------PANG
MMAR_2053|M.marinum_M -----NGGIGGDGGSGGVGGDAGAYGP-------------------PANG
TH_3810|M.thermoresistible__bu -----------DGGTPG------------------------------AHG
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
Mb1121|M.bovis_AF2122/97 ----GTGGAGGDGGAGGAGGNARLWGVGGAG-------------GAGGDG
Rv1091|M.tuberculosis_H37Rv ----GTGGAGGDGGAGGAGGNARLWGVGGAG-------------GAGGDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------AGLAGNAGLAGNAGLAGNAG-------------------LAGNA
MAV_4827|M.avium_104 ------SGLAVVGISAVLALEIALAIG------------------IRTTG
MUL_3292|M.ulcerans_Agy99 GAGGHGGMGGVGGDAG----------------------------------
MMAR_2053|M.marinum_M GAGGHGGMGGVGGDAG----------------------------------
TH_3810|M.thermoresistible__bu ESHTPGVYTDRQ--------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
Mb1121|M.bovis_AF2122/97 GAGGAGGKGGSGLSGN--------------ANGGAGGDSGR---------
Rv1091|M.tuberculosis_H37Rv GAGGAGGKGGSGLSGN--------------ANGGAGGDSGR---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAG----------------------------------
MAV_4827|M.avium_104 TVALQPTPNQHLIVPT----------------------------------
MUL_3292|M.ulcerans_Agy99 --------------LLFGSGGAGGVGG-NGAIGGTGV-------------
MMAR_2053|M.marinum_M --------------LLFGSGGAGGVGG-NGAIGGTGV-------------
TH_3810|M.thermoresistible__bu -----------------GEDGEDGTGTGIGGRGGNGG-------------
Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGAGGTGG-TGGAGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGNGGTGG-TGGNGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
Mb1121|M.bovis_AF2122/97 -------------GGTGGAGGEGGAAGLLVGTGGHGG-------------
Rv1091|M.tuberculosis_H37Rv -------------GGTGGAGGEGGAAGLLVGTGGHGG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------NAGLAGNAGLAGNAGLAGNAGLAGN-------------
MAV_4827|M.avium_104 -----------EQAPAPPPVQASAPQPKISVPEPVAAP------------
MUL_3292|M.ulcerans_Agy99 ----MSGAGGAGGDGGNGGYAQLIGDGGGGGAG-----------------
MMAR_2053|M.marinum_M ----MSGAGGAGGDGGNGGYAQLIGDGGGGGAGGAGASGAGDGDPGTAGG
TH_3810|M.thermoresistible__bu ---SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGG
Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGG
Mb1121|M.bovis_AF2122/97 ----DGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAG-GSGGSGGDGGGGA
Rv1091|M.tuberculosis_H37Rv ----DGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAG-GSGGSGGDGGGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGNAAV
MAV_4827|M.avium_104 ----KPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPV
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2053|M.marinum_M DGLLLSSASAAPLYAVEQQVLGAINAPTQALLGRPLIGDGATGAAGQNGG
TH_3810|M.thermoresistible__bu HG-------------------GRGGFLGIGGSG-------GWGGHGGNGG
Mflv_5091|M.gilvum_PYR-GCK KG-------------------GTGGTGGAGGTG----GDGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 KG-------------------GTGGTGGDGGTG----GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 RG-------------------GDGALGGNGGTGGVGLGNGGKGGNGGNGG
Mb1121|M.bovis_AF2122/97 AG-------------------PAGWLFGDGGAG----GNGGAAAAGGAGG
Rv1091|M.tuberculosis_H37Rv AG-------------------PAGWLFGDGGAG----GNGGAAAAGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AG--------------------NAAVGGVLNTG----VSGAIGGSSHVGG
MAV_4827|M.avium_104 PVP-------------------VRIPVPDPVSPPQLLAPPRLSVPQPVQP
MUL_3292|M.ulcerans_Agy99 ------------------------------------------GAGYSASG
MMAR_2053|M.marinum_M DGGLLW-----GNGGAGGTGTAAHPTGGSGGSAGLIGNGGAGGAGYSASG
TH_3810|M.thermoresistible__bu D-----------TDADGGNGGDG---------------GNGGSAG-----
Mflv_5091|M.gilvum_PYR-GCK TG---------GTGGTGGTGGAG-----------DGTGGTGGTGG----T
Mvan_1264|M.vanbaalenii_PYR-1 TG---------GTGGTGGTGGAG-----------DGLGGTGGTGG----T
MSMEG_0868|M.smegmatis_MC2_155 NGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDAD
Mb1121|M.bovis_AF2122/97 QAG--------GGGGNGGNGGNGG---------NGGNGGNGATGGWLYGN
Rv1091|M.tuberculosis_H37Rv QAG--------GGGGNGGNGGNGG---------NGGNGGNGATGGWLYGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AIN----------ESLGGSGSVG---------------GSTAVGG-----
MAV_4827|M.avium_104 PVR---------VPQPPSPPQVG-----------------GTVPQSPPQH
MUL_3292|M.ulcerans_Agy99 LPPAGIGAPGG-----------------AGGAGGSGGWLVGNGGAG----
MMAR_2053|M.marinum_M LPPAGIGAPGG-----------------AGGAGGSGGWLVGNGGAG----
TH_3810|M.thermoresistible__bu ----------------------------RGGTGGLRGVFGINGGNG----
Mflv_5091|M.gilvum_PYR-GCK GGQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG----
Mvan_1264|M.vanbaalenii_PYR-1 GGFGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG----
MSMEG_0868|M.smegmatis_MC2_155 GHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAAT
Mb1121|M.bovis_AF2122/97 GGAGGQGATAG-----------------AGGAGANGVSSTNGG-------
Rv1091|M.tuberculosis_H37Rv GGAGGQGATAG-----------------AGGAGANGVSSTNGGGTG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------GAHTGVGGGVSTGVGVG----
MAV_4827|M.avium_104 QTPPGEGTPPK-----------------PDGPGNYGGGHVPTPGAG----
MUL_3292|M.ulcerans_Agy99 -------------------GIGGIGASGSFGAPSGQGGNGGIG-------
MMAR_2053|M.marinum_M -------------------GIGGIGASGSFGAPSGQGGNGGIG-------
TH_3810|M.thermoresistible__bu --------------------RAGLGGRGXXXXGGGVGAAVRSG-------
Mflv_5091|M.gilvum_PYR-GCK -------------------GQGGTGGTGGQGGTGGTGGTGGTG-------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------GTGGTGGTGGQGGTGGTGGTGGTG-------
MSMEG_0868|M.smegmatis_MC2_155 IVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASG
Mb1121|M.bovis_AF2122/97 -------------------GNGGIGGTGGSGGAGGNAGLLGVG-------
Rv1091|M.tuberculosis_H37Rv -------------------GNGGIGGTGGSGGAGGNAGLLGVG-------
MLBr_01183|M.leprae_Br4923 --------------------MPLFLNAEPQALTAAANTLEGLS-------
MAB_4284c|M.abscessus_ATCC_199 -------------------SHVGGGISESLGGSGSVGGSTAVG-------
MAV_4827|M.avium_104 ---------------------GSGGSGGGHVPTPGAGGSGGSG-------
. .
MUL_3292|M.ulcerans_Agy99 ----GAAGLFGQGGAGGNGGQGGGDDFALSGGAGG-AGGAGGHGG-----
MMAR_2053|M.marinum_M ----GAAGLFGQGGAGGNGGQGGGDDFALSAGAGG-AGGAGGHGG-----
TH_3810|M.thermoresistible__bu --------NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG-----
Mflv_5091|M.gilvum_PYR-GCK -GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAG
Mvan_1264|M.vanbaalenii_PYR-1 -GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAG
MSMEG_0868|M.smegmatis_MC2_155 IGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATG
Mb1121|M.bovis_AF2122/97 -GAGGHGASGGAGDRGGAGGTGFISSDGGAGGDGG-DGGNGGAGG-----
Rv1091|M.tuberculosis_H37Rv -GAGGHGASGGAGDRGGAGGTGFISSDGGAGGDGG-DGGNGGAGG-----
MLBr_01183|M.leprae_Br4923 --------AATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHG-----
MAB_4284c|M.abscessus_ATCC_199 --------GGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGG-----
MAV_4827|M.avium_104 ---------GGHVPTPGTGGPGGTGGSGGGHVPTPGAGTPGGSGG-----
. . . *
MUL_3292|M.ulcerans_Agy99 -------------------QLYGDGGGGGAGGMGGSVDIAESGVTG----
MMAR_2053|M.marinum_M -------------------QLYGDGGGGGAGGVGGSVDIAESGVTG----
TH_3810|M.thermoresistible__bu -------------------IMPSSRAASARAG------------------
Mflv_5091|M.gilvum_PYR-GCK TAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG----
Mvan_1264|M.vanbaalenii_PYR-1 VAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG----
MSMEG_0868|M.smegmatis_MC2_155 TASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNAL
Mb1121|M.bovis_AF2122/97 ----------------TGGLLFGAGGNGGPGGSGGAADIGGNGGAG----
Rv1091|M.tuberculosis_H37Rv ----------------TGGLLFGAGGNGGPGGSGGAADIGGNGGAG----
MLBr_01183|M.leprae_Br4923 ------------------RQYQAHASQGATNHQDLIQS------------
MAB_4284c|M.abscessus_ATCC_199 -----------------STAVGGGAHTGVGGGVNTGVGVGSHVGGG----
MAV_4827|M.avium_104 ------------------GHLPFPGAGSTPGGSGGG--------------
MUL_3292|M.ulcerans_Agy99 -----------GRGGSGSVGGGAGLWGAGGQGG-----------------
MMAR_2053|M.marinum_M -----------GRGGSGGVGGSAGLWGAGGQGG-----------------
TH_3810|M.thermoresistible__bu ---------AACASSTSRSRRSFCCSRA----------------------
Mflv_5091|M.gilvum_PYR-GCK --AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQG
Mvan_1264|M.vanbaalenii_PYR-1 --AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQG
MSMEG_0868|M.smegmatis_MC2_155 VMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTA
Mb1121|M.bovis_AF2122/97 -----NGGGTDGNGGNGGSGGGAGSGGDGGGAGG-----------NGAWL
Rv1091|M.tuberculosis_H37Rv -----NGGGTDGNGGNGGSGGGAGSGGDGGGAGG-----------NGAWL
MLBr_01183|M.leprae_Br4923 -----------LLTSSSAYAGTETANHDSL--------------------
MAB_4284c|M.abscessus_ATCC_199 --------ISESLGGSGSVGGSTAVGGGAHTSAIN---------------
MAV_4827|M.avium_104 ---------HLPTPGAGTPGGGLGGFGGGHAPAP----------------
.
MUL_3292|M.ulcerans_Agy99 --------DGAQGGDGGAG-----VDTTTGAGG--------DGGAGAGGG
MMAR_2053|M.marinum_M --------DGAQGGDGGAG-----VDTTTGAGG--------DGGAGAGGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SAGTNGA-NGANGSQGAAG--KAGATGTTGATG--------AAGEDGDAG
Mvan_1264|M.vanbaalenii_PYR-1 SAGTNGA-NGANGSQGAAG--KAGATGTTGATG--------AAGDAGDPG
MSMEG_0868|M.smegmatis_MC2_155 ISGHGGAGNGGNGGKGADG--WVQAYDPAGPVGSKIANSSAVAGNGGDGG
Mb1121|M.bovis_AF2122/97 FGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNG--------SGGDGGDGG
Rv1091|M.tuberculosis_H37Rv FGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNG--------SGGDGGDGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------DALGGSGSVG------------------------GSTAVGG
MAV_4827|M.avium_104 -------------------------------------------GGGLGGG
MUL_3292|M.ulcerans_Agy99 TSGFLYGNGGAGGAGG----------HGGGGPGMGGDGGDGGDGGRAQLI
MMAR_2053|M.marinum_M TSGFLYGNGGAGGAGG----------HGGGGPGMGGDGGDGGDGGRAQLI
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE----
Mvan_1264|M.vanbaalenii_PYR-1 SEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE----
MSMEG_0868|M.smegmatis_MC2_155 VNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPG
Mb1121|M.bovis_AF2122/97 NGAPGGVLYGNGGAGGQGS-----SGGIGGPGATGGAGGKGGDGGDAQLI
Rv1091|M.tuberculosis_H37Rv NGAPGGVLYGNGGAGGQGS-----SGGIGGPGATGGAGGKGGDGGDAQLI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAHTSAINESMNSSIN-------------ASHSSSMNESFG---------
MAV_4827|M.avium_104 GGHAPAPGGGLGGFGG--------------GHSGGGLGGLGGGHK-----
MUL_3292|M.ulcerans_Agy99 GT-----GGNGGAGGTAAPGGTDGTAGAAGKGGVLFGTDGATG-------
MMAR_2053|M.marinum_M GN-----GGNGGAGGTAAPGGTDGTSGAAGKGGVLFGTDGATG-------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 ----GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
Mb1121|M.bovis_AF2122/97 GD--GGNGGNGGAGGTG-GTPGPGGPGGSGGLGG--LLFGQTGTAGVSP-
Rv1091|M.tuberculosis_H37Rv GD--GGNGGNGGAGGTG-GTPGPGGPGGSGGLGG--LLFGQTGTAGVSP-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------SSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MAV_4827|M.avium_104 --------------------------------------------------