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M. vanbaalenii PYR-1 Mvan_1569 (-)

annotation: hypothetical protein Mvan_1569
coordinates: 1658147 - 1659805
length: 552

MRLQYVGAVAVLSVGILTIPSIDVEPRTSVAIPPPDRSSDAVTPTGLIGRLLVPPVVPAGPPTPTPLALA
DLEPHGSSVTTKVITVEDASGVRRQVTVSELRLDKEGRSASRVIAADTDEPARGGNSSAAEPATLVIPSD
LDGDSVGRLAYLLGEVGGNIPIVALFVRNGSAEDPNAGLLIGNGGTGAAGVAGGTGGFLFGNGGAGGAGA
DGGAAGLLGRGGDGGGATAENPLAGHGGRGGWIAGDGGDGGDGLSDAGVGLPGTGGRGGDAGLLGGKGGR
GGAGGGASAQIGDTITGGAGGRGGNAGLLGTGGQGGAGGVARDTRANSGSETVIVEGGAGGQGGDGVLNA
GVGGAGGAAYTSGDDKAGDLAVGGPGGAGGSAQASSSGRGGAGGDAVATEGDALGGTGGQGGTSTRAGDG
GAGGIGGAGTSATGTGAGGTGGAGGSGATLGDGGRGGDAGYGEALDESGIAEGGTGGAGGLGGAFARGGD
GGRGGAAIGGSQESVGGDGGRGGDGGFGGLGGDGGDGASPGGQGGEGGSPGGRPGGDNGGDG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_1569--100% (552)hypothetical protein Mvan_1569
M. vanbaalenii PYR-1Mvan_3856-7e-7746.63% (401) hypothetical protein Mvan_3856
M. vanbaalenii PYR-1Mvan_3867-2e-7542.26% (452) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0545PE_PGRS6a4e-8148.56% (416) hypothetical protein Mb0545
M. gilvum PYR-GCKMflv_5091-4e-7944.44% (414) triple helix repeat-containing collagen
M. tuberculosis H37RvRv0834cPE_PGRS148e-8046.04% (454) PE-PGRS family protein
M. leprae Br4923MLBr_01556infB1e-0845.68% (81) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_4284c-1e-4034.38% (381) hypothetical protein MAB_4284c
M. marinum MMMAR_5344-2e-8347.09% (412) PE-PGRS family protein
M. avium 104MAV_4827-3e-1943.31% (157) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-5938.69% (473) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-2e-3537.82% (312) PUTATIVE -
M. ulcerans Agy99MUL_0740-8e-7746.15% (416) PE-PGRS family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0545|M.bovis_AF2122/97            --------------------------------------------------
Rv0834c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5344|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mvan_1569|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0545|M.bovis_AF2122/97            --------------------------------------------------
Rv0834c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0740|M.ulcerans_Agy99           --------------------------------------------------
MMAR_5344|M.marinum_M               --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mvan_1569|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0545|M.bovis_AF2122/97            ------------MSNLLVTPELVAAAAADLAGIGSAIGAANAAAGAPTMA
Rv0834c|M.tuberculosis_H37Rv        ------------MSFVIAAPDLVAMATEDLAGIGASLTAANAAAAVPTSG
MUL_0740|M.ulcerans_Agy99           ------------MSFVSVSPELVIDGAAALTQIGSSIDEANAAAGA-TRA
MMAR_5344|M.marinum_M               ------------MSYVFASPEVLNAAAAEVSTIGSSLQTANASAAAPTTA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mvan_1569|M.vanbaalenii_PYR-1       -----------MRLQYVGAVAVLSVGILTIPSIDVEPRTSVAIPPPDRSS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVS
MAV_4827|M.avium_104                -------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVT
MLBr_01556|M.leprae_Br4923          -----------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTV
                                                                                      

Mb0545|M.bovis_AF2122/97            LLAAG-ADEVSAAVAAVFSSYAQQYQALSAAAAAFHDQFVRALAAGAGAY
Rv0834c|M.tuberculosis_H37Rv        LLAAA-GDEVSAAIAALFSSHGQQYQAMSAQAAAFHARFVQALAGAMGAY
MUL_0740|M.ulcerans_Agy99           VLPPG-VDEVSVALAALFVAHGREYESLSAQVALFHRRFVQMLAAASGGY
MMAR_5344|M.marinum_M               LLSALGADEVSAAVTAMFGNHAQAYQAVSTQAAEFHDRFVAALTAGADAY
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mvan_1569|M.vanbaalenii_PYR-1       DAVTPTGLIGRLLVPPVVPAGPPTPTPLALADLEPHGSSVTTKVITVEDA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGP
MAV_4827|M.avium_104                GADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRD
MLBr_01556|M.leprae_Br4923          EAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKA
                                                                                      

Mb0545|M.bovis_AF2122/97            A------------------------GAEAAN---------VEQQLLNAIN
Rv0834c|M.tuberculosis_H37Rv        A------------------------AAEAANASPLQ---TLEQGLLGAIN
MUL_0740|M.ulcerans_Agy99           A------------------------EAEAANISAVAGLETVEQCVLDVIN
MMAR_5344|M.marinum_M               S------------------------SAEASTAATLQS---LPQDLLNVVN
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mvan_1569|M.vanbaalenii_PYR-1       S------------------------GVRRQVTVSELR---LDKEGRSASR
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      S-------------------------ILSPSLLSPRDNDFLSHNDTDFAS
MAV_4827|M.avium_104                A-----------------------LAARRIDNVMLVSAFLAAAALAQNVG
MLBr_01556|M.leprae_Br4923          VAG------------------------NGATTAAPVQVDHSAAVVPIVAG
                                                                                      

Mb0545|M.bovis_AF2122/97            APTLALLGRPLIGNGADGAAG-----TGQAGGAGG----LLYGNGGNGGS
Rv0834c|M.tuberculosis_H37Rv        APAAALSGRPFIGNGTNGAPG-----TGEAGGPGG----WLLGNGGNGGS
MUL_0740|M.ulcerans_Agy99           APTQALFGWSLIGNGTDGAPG-----SGQAGGNGG----LLWGNGGNGGS
MMAR_5344|M.marinum_M               APTQALLGRALIGNGANGADG-----TGQNGGDGG----LLWGNGGNGGT
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGG----LFGGNGGNGGN
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAG----LFG-NGGNGGV
Mvan_1569|M.vanbaalenii_PYR-1       VIAADTDEPARGGNSSAAEPATLVIPSDLDGDSVGRLAYLLGEVGGNIPI
TH_3810|M.thermoresistible__bu      --------------VDG---------DGGSGGRTG--LFSKLSRGGDGGD
MAB_4284c|M.abscessus_ATCC_199      HNPIASGNQVMSPSGNVDSFNR----GPLLDLSFG---DLQFGNRDTTAI
MAV_4827|M.avium_104                GAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQL
MLBr_01556|M.leprae_Br4923          EGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAP-------HPGHPGM
                                                                                      

Mb0545|M.bovis_AF2122/97            GAAGQAGGAGGAAG---LIGHGGTGGVGGT------GAAGG-AGGTGGWL
Rv0834c|M.tuberculosis_H37Rv        GAPGQTGGAGGAAG---LLGHGGTGGAGGT------GASGG-KGGTGGWL
MUL_0740|M.ulcerans_Agy99           GGVGQAGGAGGSAG---LLGHGGAGGAGGVSGVSAVGATGG-AGGNGGWL
MMAR_5344|M.marinum_M               GAAGQAGGNGGAAG---LIGNGGAGGAGGAG---ATGGAGG-TGGAGGWL
Mflv_5091|M.gilvum_PYR-GCK          GLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGAT
MSMEG_0868|M.smegmatis_MC2_155      GWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTG
Mvan_1569|M.vanbaalenii_PYR-1       VALFVRNGSAEDPNAGLLIGNGGTGAAGVAG-------------GTGGFL
TH_3810|M.thermoresistible__bu      GGLGGNGGHGGGTGIISLLSLAGNGGNGGNG------------YRTTDNN
MAB_4284c|M.abscessus_ATCC_199      GDGAVAVGGSNSGP--IASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQ
MAV_4827|M.avium_104                SAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETA
MLBr_01556|M.leprae_Br4923          PTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRPSASPSSMS
                                                                                      

Mb0545|M.bovis_AF2122/97            FGNGGAG-------------------------GTGGAVTGVST-------
Rv0834c|M.tuberculosis_H37Rv        WGSGGAGGAGGSGGGSGGAGGNALMFGIGGNGGAGGAASGVGNGG-----
MUL_0740|M.ulcerans_Agy99           YGNGGAGGLGGQG------------VLIGGNGGAGGAARFFGAGG-----
MMAR_5344|M.marinum_M               TGAGGTGGAGGTG-----------TSGGGGMGGAGGQAGWLSGAGG----
Mflv_5091|M.gilvum_PYR-GCK          GATGVTSGVVGGNGE------DAVGYGATGAAGAAGAAGAAGAAG-----
MSMEG_0868|M.smegmatis_MC2_155      GGTGGTGGIGGTGGG------LFGLLGHSGSTGAAGAAGNGGDGGNGGFG
Mvan_1569|M.vanbaalenii_PYR-1       FGNGGAGGAGADG----------------------GAAGLLGRGG-----
TH_3810|M.thermoresistible__bu      ALDGGHGGNG-------------------------GNVGFFSLFN-----
MAB_4284c|M.abscessus_ATCC_199      TRVGGDYTNVSGHG----------------SADIDKSVTVVDDHSQ----
MAV_4827|M.avium_104                LARGAALAAANAP------------------LFASSTAALAYAQD-----
MLBr_01556|M.leprae_Br4923          PRPGGAVGGGGPRPP------------RTGVPRPGGGRPGAPVGGR----
                                       *                                              

Mb0545|M.bovis_AF2122/97            ------------------TGGPGGHG------------GDAGLYG-----
Rv0834c|M.tuberculosis_H37Rv        ------------------VGGAGGAGGALVAIGGAGGAGGAATTG-----
MUL_0740|M.ulcerans_Agy99           ------------------TGGAGGLGLGDTGGIGGIGGNAGALFG-----
MMAR_5344|M.marinum_M               ------------------TGGAGGAGDNGSGGSGGSG-GAGGLFN-----
Mflv_5091|M.gilvum_PYR-GCK          ---------AVG--SAGAAGEAGETGTWGNAGLPGKAGDAGGAG----AV
MSMEG_0868|M.smegmatis_MC2_155      YVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILI
Mvan_1569|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------RNTTNINDSFNTDRSTNIGSGNTTNTEIG-----
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          -------------------SDAGGGNYRGGGVGALPGGGSGGFRG-----
                                                                                      

Mb0545|M.bovis_AF2122/97            -----------FGGAGGAG------------------------GFGQSGA
Rv0834c|M.tuberculosis_H37Rv        -----------TGGAGGAGSNALG----------------LFLGLGGSGG
MUL_0740|M.ulcerans_Agy99           -----------PGGAGGPGGAG---------------------GNGGAGG
MMAR_5344|M.marinum_M               -----------AGGAGGAGGTSLGNSGDAGGTGGAGGAGGIVAGVGGAGG
Mflv_5091|M.gilvum_PYR-GCK          GAAG---AAGTVGTAGATGGTG-------------------TGANGGAGG
MSMEG_0868|M.smegmatis_MC2_155      GANGGTVDGHAIGGNGGNGGNGSTT---------------AAGGNGGTGG
Mvan_1569|M.vanbaalenii_PYR-1       ------------DGGGATAENP----------------------LAGHGG
TH_3810|M.thermoresistible__bu      -----------LGGAGGWGGSG----------------------VDGVDV
MAB_4284c|M.abscessus_ATCC_199      -----------SHNQANIGTST---------------------SAGGSAA
MAV_4827|M.avium_104                ------------PGTGAVDQYS----------------------LPDYLY
MLBr_01556|M.leprae_Br4923          -----------RPGGGGHGGGGRPGQ--------------RGGAAGAFGR
                                                   .                                  

Mb0545|M.bovis_AF2122/97            AGG--------------AGGAG------GAGG------------------
Rv0834c|M.tuberculosis_H37Rv        QGGD---------SAMGSGGAG------GAGGSGGAASPFGID-------
MUL_0740|M.ulcerans_Agy99           SGG----------ALADDGGDG------GAGG------------------
MMAR_5344|M.marinum_M               AGGL---------SSSGDGGAG------GTGGDGGFLLGQG---------
Mflv_5091|M.gilvum_PYR-GCK          VG-----GVGGTGAAGAAGGAG------GLGETGTTG-------------
MSMEG_0868|M.smegmatis_MC2_155      TGRVIAEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSG
Mvan_1569|M.vanbaalenii_PYR-1       RGG-----------------------------------------------
TH_3810|M.thermoresistible__bu      VGG---------------NPDG----------------------------
MAB_4284c|M.abscessus_ATCC_199      VGGN----------AGLAGNAG----------------------------
MAV_4827|M.avium_104                VPVD-----------PEPGDDE----------------------------
MLBr_01556|M.leprae_Br4923          PGGAPRRGRKSKRQKRQEYDSMQAP-------------------------
                                                                                      

Mb0545|M.bovis_AF2122/97            -WLYGDGGDGGAGGNG----------------------------------
Rv0834c|M.tuberculosis_H37Rv        IGIGGAGGHGGAGTNGGAGGAGGAGGSSG---------------------
MUL_0740|M.ulcerans_Agy99           --AGGIGGNGGAGTTGLAG-------------------------------
MMAR_5344|M.marinum_M               -AAGGAGGNGGAGATGISGPAGQTGG------------------------
Mflv_5091|M.gilvum_PYR-GCK          -GAGGVGGQGTAGGTGGVGGIG-----------------------GAGST
MSMEG_0868|M.smegmatis_MC2_155      TATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSL
Mvan_1569|M.vanbaalenii_PYR-1       -WIAGDGGDGGDGLSDAG--------------------------------
TH_3810|M.thermoresistible__bu      ---GTPGAHGESHTPGVYT-------------------------------
MAB_4284c|M.abscessus_ATCC_199      -LAGNAGLAGNAGLAGNAGLAG----------------------------
MAV_4827|M.avium_104                LAYSAVGEEDAESPTVVIEKLFLPED------------------------
MLBr_01556|M.leprae_Br4923          -VVGGVRLPHGNGETIRLARGASLSDFAEKIDAN----------------
                                                                                      

Mb0545|M.bovis_AF2122/97            ------------------------------GNESGTGVSGVGGVG-----
Rv0834c|M.tuberculosis_H37Rv        ---------------TVFALDLSWGGAGGNGGAATTGTGGAGGTGGFAVA
MUL_0740|M.ulcerans_Agy99           ----------------------------HIGIDMNGGAGGVGGAGG----
MMAR_5344|M.marinum_M               ----------------------------DGGAAGNGGNGGAGGKGGLLLG
Mflv_5091|M.gilvum_PYR-GCK          GAVGG-----------VGGKGIQGGQGLQGGKGGDGGAGGKGGDADSMGS
MSMEG_0868|M.smegmatis_MC2_155      GGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAA
Mvan_1569|M.vanbaalenii_PYR-1       -----------------------------VGLPGTGGRGGDAG-------
TH_3810|M.thermoresistible__bu      ------------------------------DRQGEDGEDGTG--------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------NAGLAGNAGLAGNAGLAG----
MAV_4827|M.avium_104                ----------------------------SEPRRRPVLLVGSG--------
MLBr_01556|M.leprae_Br4923          ------------------PAALVQALFNLGEMVTATQSVGDETLELLGSE
                                                                           *          

Mb0545|M.bovis_AF2122/97            -----------------------GAGGAGG--------------------
Rv0834c|M.tuberculosis_H37Rv        PDFI------------GFGAAYGGAGGLGG--------------------
MUL_0740|M.ulcerans_Agy99           ---------------------NGGAGGTGG--------------------
MMAR_5344|M.marinum_M               ------------------GGGRGGAGGLGG--------------------
Mflv_5091|M.gilvum_PYR-GCK          ------------------AGATGGKGGNGGNGGRGGLFG-----------
MSMEG_0868|M.smegmatis_MC2_155      GATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGH
Mvan_1569|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------NAGLAGNAG--------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          MNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPP----------
                                                                                      

Mb0545|M.bovis_AF2122/97            ---LLFGNGGDG-------------------------GVGGDGGDGSSTQ
Rv0834c|M.tuberculosis_H37Rv        ---AATGAGGTGGTGGVGAGGFAA----------LGVGVGGAGGAGGAAT
MUL_0740|M.ulcerans_Agy99           ---DAGHAQAGG----------------------YSDGLQGAGGDGGHG-
MMAR_5344|M.marinum_M               ---AGGAGGNGGIGAAATTPGATG----------GDGGNGGLGGTGGTGG
Mflv_5091|M.gilvum_PYR-GCK          ----KGGNAGNG----------------------ADGGTGGAGGAGGTGG
MSMEG_0868|M.smegmatis_MC2_155      GGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGG
Mvan_1569|M.vanbaalenii_PYR-1       ----------------------------------LLGGKGGRGGAGGGAS
TH_3810|M.thermoresistible__bu      ------------------------------------TGIGGRGGNGGSSS
MAB_4284c|M.abscessus_ATCC_199      ---LAGNAGLAG-----------------------NAGLAGNAGLAGNAG
MAV_4827|M.avium_104                -----------------------------------LAVVGISAVLALEIA
MLBr_01556|M.leprae_Br4923          -VVTVMGHVDHGKTRLLDTIRKAN-----------VREAEAGGITQHIGA
                                                                              .       

Mb0545|M.bovis_AF2122/97            DSGGDGGAG--------------------------GAGGAGG-----WLL
Rv0834c|M.tuberculosis_H37Rv        ETGGIGGAGG------------------LGVGLLGGAGGAGGPGGA-ASA
MUL_0740|M.ulcerans_Agy99           GSGGVAGDGG------------------RGADAAAGSGLAGGDG---GRG
MMAR_5344|M.marinum_M               NGGAGGQAGL------------------FGAQGQQGAGGAGGNGGTGGIA
Mflv_5091|M.gilvum_PYR-GCK          -TGGAGGTGG-----------------TGGTGGIGGAGSTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      ATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNG
Mvan_1569|M.vanbaalenii_PYR-1       AQIGDTITGG--------------------------AGGRGGNAGLLGTG
TH_3810|M.thermoresistible__bu      GTHPMAEDGE---------------------HVKALDGRPGLDGGNGSHG
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAGN---------------------AGLAGNAGLAGNAGLAGNA
MAV_4827|M.avium_104                LAIGIRTTGT------------------VALQPTPNQHLIVPTEQAPAPP
MLBr_01556|M.leprae_Br4923          YQVGVDLDGSERLITFIDTPG------HEAFTAMRARGAKATDIAILVVA
                                            *                                         

Mb0545|M.bovis_AF2122/97            GNGGAGGA-------GGAAS--IKVATGGLGGDGGDA------GLFGFGG
Rv0834c|M.tuberculosis_H37Rv        GSGGHGGT-------GGDALGLIGAGIGGVGGVGGAA------TDTGGNG
MUL_0740|M.ulcerans_Agy99           GDPGAGGE-------GGAAGGGSVAGTAGLDGIGPNS------GGNGGNG
MMAR_5344|M.marinum_M               GDGGTGGAGDATHLDGGKGGNGGNPGLGGTGGAGGTG------ASTGTHG
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      GAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNG
Mvan_1569|M.vanbaalenii_PYR-1       GQGGAGGVARDTRANSGSETVIVEGGAGGQGGDGVLN------AGVGGAG
TH_3810|M.thermoresistible__bu      GNGGHGGR-------GGFLGIGGSGGWGGHGGNGGDT------DADGGNG
MAB_4284c|M.abscessus_ATCC_199      GLAGNAGLAG----NAGLAGNAAVAGNAAVAGNAAVAG----NAAVGGVL
MAV_4827|M.avium_104                PVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPA
MLBr_01556|M.leprae_Br4923          ADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLV
                                       .                             .                

Mb0545|M.bovis_AF2122/97            DGGWGG----------RGVDARFGAAG------------GAAGAGGAGG-
Rv0834c|M.tuberculosis_H37Rv        GAGGSG----------TGLLGGVGGAGG----HGGGASVGTGGSGGAGGD
MUL_0740|M.ulcerans_Agy99           GHGGSGA---------VGVEGGAGSAG------------GAGGRGGDGG-
MMAR_5344|M.marinum_M               SAGATP----------TTVAGNGGKGGD----GYTPTTPGADGGNGGAGG
Mflv_5091|M.gilvum_PYR-GCK          GTGGTG---------GTGGTGGTGGAG-----------DGTGGTGGTGG-
MSMEG_0868|M.smegmatis_MC2_155      GNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGN
Mvan_1569|M.vanbaalenii_PYR-1       GAAYTS---------------GDDKAGD----------LAVGGPGGAGG-
TH_3810|M.thermoresistible__bu      GDGGNG---------------------------------GSAGRGGTGG-
MAB_4284c|M.abscessus_ATCC_199      NTGVSG------------AIGGSSHVGG-------AINESLGGSGSVGG-
MAV_4827|M.avium_104                APPVVP----------VPVVVPPVPVPVP---------VRIPVPDPVSPP
MLBr_01556|M.leprae_Br4923          AEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAALDLRANSGMEAQGVA
                                                                                   .  

Mb0545|M.bovis_AF2122/97            --WLYGDGGAGG------------------------------VGGVGGAV
Rv0834c|M.tuberculosis_H37Rv        GFGFVGAGGNGGNAGTG-----VGVNGANGGNGGSATGALAAVGGAGAAG
MUL_0740|M.ulcerans_Agy99           ---AYGNGGVSGN------------------------------GGAGGAG
MMAR_5344|M.marinum_M               NGGLYGNGGNGGNGG----------NGTVGAAGVNPTPNPVLGQADPGTD
Mflv_5091|M.gilvum_PYR-GCK          ---TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG
MSMEG_0868|M.smegmatis_MC2_155      GDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTG
Mvan_1569|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -STAVGGGAHTGVGG----------------------------GVSTGVG
MAV_4827|M.avium_104                QLLAPPRLSVPQPVQPP---------------------------------
MLBr_01556|M.leprae_Br4923          IEAHLDRGRGPVATVLVQRG------------------------------
                                                                                      

Mb0545|M.bovis_AF2122/97            F---------------------SLSSGDGGAGGAGGGG--GWLFGNG---
Rv0834c|M.tuberculosis_H37Rv        G---------------------DATSGTGGFGGAGGSAR-GLIFALG---
MUL_0740|M.ulcerans_Agy99           --------------------------SPGAHGGTAGED--GFNAGDG---
MMAR_5344|M.marinum_M               G---------------------IDTTGIGGDGGPGSPG--AFAGQQG---
Mflv_5091|M.gilvum_PYR-GCK          -----------------------GQGGTGGTGGQGGTGGTGGTGGTG---
MSMEG_0868|M.smegmatis_MC2_155      GAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSA
Mvan_1569|M.vanbaalenii_PYR-1       ----------------------SAQASSSGRGGAGGDAVATEGDALG---
TH_3810|M.thermoresistible__bu      --------------------------LRGVFGINGGNG----RAGLG---
MAB_4284c|M.abscessus_ATCC_199      VG---------------------SHVGGGISESLGGSGSVGGSTAVG---
MAV_4827|M.avium_104                ----------------------VRVPQPPSPPQVGGTVPQSPPQHQTP--
MLBr_01556|M.leprae_Br4923          ----------------------TLRIGDSVVAGDAYGRVRRMVDEHG---
                                                                      .               

Mb0545|M.bovis_AF2122/97            -----GDGGAG-------GGGGGRFGSGSG---------AGGDGAVGGAG
Rv0834c|M.tuberculosis_H37Rv        -----GAGAAGGDASTGVGGPGGPGGTGTASSPFGIAIAIGGAGAQGGAG
MUL_0740|M.ulcerans_Agy99           -----GHGGAGG----AGGGGGAKGGVGGAG-------GSGGVGGQGGTG
MMAR_5344|M.marinum_M               -----GNGGEGGTG-VDVGGGGGDGQTGGPGTLGGNG-GNGGTASMGGSG
Mflv_5091|M.gilvum_PYR-GCK          -----GTGGAGGDG--GLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155      VASGIGAGGNGGDG--IDGGLGGNGGDGVVNTTANAANPGSATGTATGGD
Mvan_1569|M.vanbaalenii_PYR-1       -------------------GTGGQGGTSTRAG-------DGGAGGIGGAG
TH_3810|M.thermoresistible__bu      -------------------GRGXXXX-------------GGGVGAAVRSG
MAB_4284c|M.abscessus_ATCC_199      -----------------GGAHTGVGGGVSTGVGVGSHVGGGISESLGGSG
MAV_4827|M.avium_104                ------------------PGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSG
MLBr_01556|M.leprae_Br4923          ----VDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSAR
                                                       .                              

Mb0545|M.bovis_AF2122/97            GAGAWFGNG----GAG----------GVGGGGGRGTTAIGG--DGGAG--
Rv0834c|M.tuberculosis_H37Rv        TSGATGGAG----GDGVFEGIAVLGLGFGGAAGAGGAATGDGATGGAGGF
MUL_0740|M.ulcerans_Agy99           GDGATGLSG----KAG---------TGTDGESGGRGGHAGNGGNGGNGG-
MMAR_5344|M.marinum_M               GGGGSGGDGGGGGGAGGNGAIGGFSGGNGGAGGNGGSGGGAGGNGGDGG-
Mflv_5091|M.gilvum_PYR-GCK          G--QAGTAGKG--GLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQ
MSMEG_0868|M.smegmatis_MC2_155      GGKATGTASQG--GNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGV
Mvan_1569|M.vanbaalenii_PYR-1       TSATGTGAG------------------GTGGAGGSGATLGDGGRGGDAG-
TH_3810|M.thermoresistible__bu      NGVFSGGGG-------------------TPSAGFGVPTTIQFPAGSCTS-
MAB_4284c|M.abscessus_ATCC_199      SVGGSTAVG------------------GGAHTGVGGGVNTGVGVGSHVG-
MAV_4827|M.avium_104                GGHVPTPGA-------------------GGSGGSGGGHVPTPGTGGPGG-
MLBr_01556|M.leprae_Br4923          KRNALAARSRK-----------RISLEDLDSALKETSQLNLILKGDNAGT
                                            .                                   .     

Mb0545|M.bovis_AF2122/97            -------------------GAGGAGGWLYGDGGAGGAGGGGGR-------
Rv0834c|M.tuberculosis_H37Rv        GGAGA-GIANFLGFSVLHGGAGGAGGTATGTGGNGGAGGGGGLSSPVILG
MUL_0740|M.ulcerans_Agy99           -------------------RGGSAHASLVGKAGNGGFGGTGGNS------
MMAR_5344|M.marinum_M               NATDL-MFANGGNGGNGGTGGEGTAGSGGGSGGNGGAGGAGGLYG-----
Mflv_5091|M.gilvum_PYR-GCK          GATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG---------
MSMEG_0868|M.smegmatis_MC2_155      AGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIH
Mvan_1569|M.vanbaalenii_PYR-1       -------------------YGEALDESGIAEGGTGGAGGLGG--------
TH_3810|M.thermoresistible__bu      ---------------------RAVSREGIMPSSRAASARAG---------
MAB_4284c|M.abscessus_ATCC_199      ---------------------GGISESLGGSGSVGGSTAVGGG-------
MAV_4827|M.avium_104                --------------------TGGSGGGHVPTPGAGTPGGSGGG-------
MLBr_01556|M.leprae_Br4923          VEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIG----
                                                                            .         

Mb0545|M.bovis_AF2122/97            -----------------GGTGNDGGDGG----------------------
Rv0834c|M.tuberculosis_H37Rv        IGIGGAGGDGGGALGVLGGMGGDGGDGGEAVAVGIAVGGAGGAGGAAPTG
MUL_0740|M.ulcerans_Agy99           ----------------FGGVSGNGGNGG----------------------
MMAR_5344|M.marinum_M               -NGGNGGTGGSGAAGGVGAMGGNGGNGG----------------------
Mflv_5091|M.gilvum_PYR-GCK          --TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAG
MSMEG_0868|M.smegmatis_MC2_155      GAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAG
Mvan_1569|M.vanbaalenii_PYR-1       ----------------AFARGGDGGRGG----------------------
TH_3810|M.thermoresistible__bu      -----------------AACASSTSRSR----------------------
MAB_4284c|M.abscessus_ATCC_199      ----------AHTSAINDALGGSGSVGG----------------------
MAV_4827|M.avium_104                ----------------HLPFPGAGSTPG----------------------
MLBr_01556|M.leprae_Br4923          -------FNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKP
                                                                                      

Mb0545|M.bovis_AF2122/97            ---DGGRGGDAQ-LLGNGGDGG--------------------AGGAGG--
Rv0834c|M.tuberculosis_H37Rv        NGGAGGNGGDALGLVGVGGNGGNA-----------GTGFGANTGGNGGDT
MUL_0740|M.ulcerans_Agy99           ---DGGHALHGQ----PGGHGG--------------------QGGHGG--
MMAR_5344|M.marinum_M               ---SGGTGTTAG-ADGNGGNGGTG-----------GAGGNGGNGGTGG-A
Mflv_5091|M.gilvum_PYR-GCK          EDGDAGSGGSG-INGGAGGAGG-----------------AGGEGGEGGDG
MSMEG_0868|M.smegmatis_MC2_155      NGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDG
Mvan_1569|M.vanbaalenii_PYR-1       ----AAIGGSQESVGGDGGRGG--------------------DGGFGG--
TH_3810|M.thermoresistible__bu      ----RSFCCSRA--------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---STAVGGGAHTSAINESMNS------------------SINASHSS--
MAV_4827|M.avium_104                -----GSGGGHLPTPGAGTPGG-------------------GLGGFGG--
MLBr_01556|M.leprae_Br4923          IYEENQLGRAEIRALFRSSKVGIIAG------------CIISSGVVRRNA
                                                                                      

Mb0545|M.bovis_AF2122/97            -----------PAGFGASPGAGAAGGGG--GAGG--SLFGSPGTTGPHG-
Rv0834c|M.tuberculosis_H37Rv        TIVVNGMLAPSTLGYGGNGGNGVNGGAG--GTGGKAGVFGAPGQNGLP--
MUL_0740|M.ulcerans_Agy99           -----------VAHIDGSDYPGWPGLPG--DVGYQDGTGGGGGTGGAGGH
MMAR_5344|M.marinum_M               AGSGGMFGQMGDAGDGGDAGTGGEGGDG--GTGGSGAMSGQTGDQGAGGT
Mflv_5091|M.gilvum_PYR-GCK          GKGGAG--AEGGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGA
MSMEG_0868|M.smegmatis_MC2_155      SEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGT
Mvan_1569|M.vanbaalenii_PYR-1       ------------LGGDGGDGASPGGQGG---EGGSPGGRPGGDNGGDG--
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------SMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGA
MAV_4827|M.avium_104                --------GHAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGG
MLBr_01556|M.leprae_Br4923          KVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDV
                                                                                      

Mb0545|M.bovis_AF2122/97            ------------
Rv0834c|M.tuberculosis_H37Rv        ------------
MUL_0740|M.ulcerans_Agy99           AP----------
MMAR_5344|M.marinum_M               PGTAGASG----
Mflv_5091|M.gilvum_PYR-GCK          AGDSDD------
MSMEG_0868|M.smegmatis_MC2_155      TGANNP------
Mvan_1569|M.vanbaalenii_PYR-1       ------------
TH_3810|M.thermoresistible__bu      ------------
MAB_4284c|M.abscessus_ATCC_199      EHH---------
MAV_4827|M.avium_104                HK----------
MLBr_01556|M.leprae_Br4923          IESYELVEKQRA