For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSNVMVVPGMLSAAAADVASIGAALSAANGAAAPTTAGVLAAGADEVSAAIASLFSGYARDYQALSAQMA RFHQQFVQALTASVGSYAAAEAANASPLQALEQQVLAAINAPTQTLLGRPLIGNGADGLPGQNGGAGGLL WGNGGNGGAGDAAHPNGGNGGDAGMFGNGGAGGAGYSPAAGTGAAGGAGGAGGAGGWLSGNGGAGGNGGT GASGADGGGGLPPVPASPGGNGGGGGAGGAAGMFGTGGAGGTGGDGGAGGAGDSPNSGANGARGGDGGNG AAGGAGGRLFGNGGAGGNGGTAGQGGDGGTALGAGGIGGDGGTGGAGGTGGTAGIGGSSAGAGGAGGDGG AGGNGGGSSMIGGKGGTGGNGGVGGTGGASALTIGNGSSAGAGGAGGAGGTGGTGGYIESLDGKGQAGNG GNGGNGAAGGAGGGGTGAGGNGGAGGNGGDGGPSQGGGNPGFGGDGGTGGPGGVGVPDGIGGANGAQGKH G
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1476c | PE_PGRS26 | - | 100% (491) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | e-145 | 50.78% (577) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb3621c | PE_PGRS58 | e-143 | 53.70% (568) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-99 | 48.07% (491) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1441c | PE_PGRS26 | 0.0 | 99.59% (491) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-13 | 41.76% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-48 | 38.61% (373) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_2596 | - | 1e-171 | 61.48% (514) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 2e-24 | 42.47% (186) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-72 | 40.43% (517) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-46 | 40.56% (323) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3292 | - | 1e-148 | 52.47% (587) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 6e-96 | 48.64% (442) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2596|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2596|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2596|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2596|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mb1476c|M.bovis_AF2122/97 --------------------------------------------------
Rv1441c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2596|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------MSIIDFILN
MAV_4827|M.avium_104 ----------------------------------------------MNIV
TH_3810|M.thermoresistible__bu ------------VDGDGGSGGRTGLFSKLS---------RGGDGGD----
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
Mb1476c|M.bovis_AF2122/97 -------MS-NVMVVPGMLSAAAADVASIG---AALSAANGAAAPT----
Rv1441c|M.tuberculosis_H37Rv -------MS-NVMVVPGMLSAAAADVASIG---AALSAANGAAAPT----
MMAR_2596|M.marinum_M -------MS-YLTVAPEALSAATSDAAEIG---SALAAANAAAAAR----
MUL_3292|M.ulcerans_Agy99 -------MS-YVIAAPEMLAGAATDLAGIG---AALQSANGAAAAP----
MLBr_01183|M.leprae_Br4923 -------MPLFLNAEPQALTAAANTLEGLS---AATVASNAAAAQL----
MAB_4284c|M.abscessus_ATCC_199 LFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASN----
MAV_4827|M.avium_104 LGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDR----
.
TH_3810|M.thermoresistible__bu --------------------GGLGGNGGHGGGTGIISLLSLAG--NGGNG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
Mb1476c|M.bovis_AF2122/97 -------------------TAGVLAAGADEVSAAIASLFSGYA--RDYQA
Rv1441c|M.tuberculosis_H37Rv -------------------TAGVLAAGADEVSAAIASLFSGYA--RDYQA
MMAR_2596|M.marinum_M -------------------TAGLLSAGGDEVSAAIAAVFSAHG--VQYQA
MUL_3292|M.ulcerans_Agy99 -------------------ITGVLAAGADEISAAVAALFSGHA--LDYQA
MLBr_01183|M.leprae_Br4923 -------------------TTEIAPPAADDVSILLAHFFSGHG--RQYQA
MAB_4284c|M.abscessus_ATCC_199 --------------YGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILS
MAV_4827|M.avium_104 ------------------VISAILGTREGAADAGLQLSSIGVTWTDQLEA
: .
TH_3810|M.thermoresistible__bu GNGYRTTDNNALDGGHGGNGGNVGFFSLFN--------------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
Mb1476c|M.bovis_AF2122/97 LSAQMARFHQQFVQALTASVGSYAAAEAAN--------------------
Rv1441c|M.tuberculosis_H37Rv LSAQMARFHQQFVQALTASVGSYAAAEAAN--------------------
MMAR_2596|M.marinum_M ISAQMAQFHRQFAQALSAANRSYALAEAAN--------------------
MUL_3292|M.ulcerans_Agy99 LSTQMAGFHQQFVTALNSAGASYAAAEAAS--------------------
MLBr_01183|M.leprae_Br4923 HASQGATNHQDLIQSLLTSSSAYAGTETAN--------------------
MAB_4284c|M.abscessus_ATCC_199 PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSP----------------
MAV_4827|M.avium_104 AALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMG-----------YER
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
Mb1476c|M.bovis_AF2122/97 -ASPLQALEQQVLAAINAPTQTLLGRPLIGNGADG---------------
Rv1441c|M.tuberculosis_H37Rv -ASPLQALEQQVLAAINAPTQTLLGRPLIGNGADG---------------
MMAR_2596|M.marinum_M -ASPLQAIEQQLLAAINAPTQTLLGRPLIGNGADG---------------
MUL_3292|M.ulcerans_Agy99 -ANPLQAVEQQLLGVINAPTQALLGRPLIGDGTAG---------------
MLBr_01183|M.leprae_Br4923 -HDSL---------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -SGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG----------------
MAV_4827|M.avium_104 TAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYG-----------DA
TH_3810|M.thermoresistible__bu ----------------LGGAGGWGGSG-----------------------
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
Mb1476c|M.bovis_AF2122/97 LPGQNGGAGG-----LLWGNGGNGGAG-------------DAAHPNGGNG
Rv1441c|M.tuberculosis_H37Rv LPGQNGGAGG-----LLWGNGGNGGAG-------------DAAHPNGGNG
MMAR_2596|M.marinum_M APGQNGAAGG-----LLWGNGGAGGAG-------------TATHTAGGNG
MUL_3292|M.ulcerans_Agy99 APGQNGGDGG-----LLWGNGGAGGVG-------------TAAHPTGGSG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AVAVGGSNSG----PIASGQGSTAVNG--------DVRDSNIINADHGSN
MAV_4827|M.avium_104 AGQLSAMVAGLEKLESLPGGLLLVGSG-------------VDVAPLKQVL
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
Mb1476c|M.bovis_AF2122/97 GDAGMFGNGGAG----------------------GAGYSP----------
Rv1441c|M.tuberculosis_H37Rv GDAGMFGNGGAG----------------------GAGYSP----------
MMAR_2596|M.marinum_M GDAGLIGNGGAG----------------------GAGFN-----------
MUL_3292|M.ulcerans_Agy99 GSAGLIGTGGAG----------------------GAGYGPAAQTGATGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGVDQSQTRVGG---------------DYTNVSGHGSADIDKSVTVVDDH
MAV_4827|M.avium_104 QTTTFLDVSVAE-----------------------EPETALARGAALAAA
TH_3810|M.thermoresistible__bu ------------VDGVDVVGGNPD--------------------------
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
Mb1476c|M.bovis_AF2122/97 ------------AAGTGAAGGAGGAGGAGG--WLSGNGG-----------
Rv1441c|M.tuberculosis_H37Rv ------------AAGTGAAGGAGGAGGAGG--WLSGNGG-----------
MMAR_2596|M.marinum_M -------------AGNGAAGGAGGAGGHGG--WLYGNGG-----------
MUL_3292|M.ulcerans_Agy99 GGVGGTGGSGLDGPDSGAAGGAGGSGGSGGAARLFGNGG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIG----------T
MAV_4827|M.avium_104 NAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPE-----------
TH_3810|M.thermoresistible__bu -----------------------------------------------GGT
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
Mb1476c|M.bovis_AF2122/97 AGGNGGTGASGADGGGGLPPVPASP----------------------GGN
Rv1441c|M.tuberculosis_H37Rv AGGNGGTGASGADGGGGLPPVPASP----------------------GGN
MMAR_2596|M.marinum_M VGGVGGT------GGAGVPAVPT------------------------GGD
MUL_3292|M.ulcerans_Agy99 AGGSGGK------GGNGGSAIET------------------------GND
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 STSAGGSAAVGGNAGLAGNAGLAGN----------------------AGL
MAV_4827|M.avium_104 PGDDELAYSAVGEEDAESPTVVIEK----------------------LFL
TH_3810|M.thermoresistible__bu PGAHGESHTPGVYTD-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
Mb1476c|M.bovis_AF2122/97 GGGGGAGGAAGMFGT-----------------------------------
Rv1441c|M.tuberculosis_H37Rv GGGGDAGGAAGMFGT-----------------------------------
MMAR_2596|M.marinum_M GGAGGVGGAAGLWGD-----------------------------------
MUL_3292|M.ulcerans_Agy99 GAAGAGGHGGWLVGN-----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGN-----------------------------------
MAV_4827|M.avium_104 PEDSEPRRRPVLLVG-----------------------------------
TH_3810|M.thermoresistible__bu -------------RQGEDGEDGTGTGIGGRGGNGG---------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
Mb1476c|M.bovis_AF2122/97 -----------GGAGGTGGDGGAG---GAGDSPNS---------------
Rv1441c|M.tuberculosis_H37Rv -----------GGAGGTGGDGGAG---GAGDSPNS---------------
MMAR_2596|M.marinum_M -----------GGAGGAGGQGGAG-RVGAAGGASS---------------
MUL_3292|M.ulcerans_Agy99 -----------GGIGGDGGSGGVGGDAGAYGPPAN---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------AGLAGNAGLAGNAGLAGNAGLAGNAG-------------
MAV_4827|M.avium_104 -----------SGLAVVGISAVLALEIALAIGIRTTG------------T
TH_3810|M.thermoresistible__bu ---SSSGTHPMAEDGEHVKALDGRPGLDGGNGSHGGNGGHGGRGGFLGIG
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
Mb1476c|M.bovis_AF2122/97 ---GANGARGGDGGNG---------AAGGAGGRLFGNGGAGGNG---GTA
Rv1441c|M.tuberculosis_H37Rv ---GANGARGGDGGNG---------AAGGAGGRLFGNGGAGGNG---GTA
MMAR_2596|M.marinum_M ---GGTGGHGGVGGIG---------GSGGAGGWVAGNGGAG------GAG
MUL_3292|M.ulcerans_Agy99 ---GGAGGHGGMGGVGGDA--GLLFGSGGAGG-VGGNGAIGGTGVMSGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGNAGLAGNAG-LAGNAGLAGNAGLAGNA
MAV_4827|M.avium_104 VALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPPVA
TH_3810|M.thermoresistible__bu GSGGWGGHGGNGGDTDADGGNGGDGGNG------------GSAGRGGTGG
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
Mb1476c|M.bovis_AF2122/97 GQGGDGGTALGAG-GIG--GDGGTGGAG---------------GTGGTAG
Rv1441c|M.tuberculosis_H37Rv GQGGDGGTALGAG-GIG--GDGGTGGAG---------------GTGGTAG
MMAR_2596|M.marinum_M GAGGMGGMGGTGA-SIG--GGGGTGGAG---------------GTGAAGG
MUL_3292|M.ulcerans_Agy99 GAGGDGGNGGYAQ-LIGDGGGGGAGGAGYSASGLPPAGIGAPGGAGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAG-LAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGVLN
MAV_4827|M.avium_104 APLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPV
TH_3810|M.thermoresistible__bu LR---------------------------GVFGINGGNGR----------
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
Mb1476c|M.bovis_AF2122/97 IG---------------------------GSSAGAGGAGG----------
Rv1441c|M.tuberculosis_H37Rv IG---------------------------GSSAGAGGAGG----------
MMAR_2596|M.marinum_M DG---------------------------GWLFGDGGSGG----------
MUL_3292|M.ulcerans_Agy99 SG---------------------------GWLVGNGGAGG----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TG-------------------------VSGAIGGSSHVGG----------
MAV_4827|M.avium_104 SP--------------------------PQLLAPPRLSVPQPVQPPVRVP
TH_3810|M.thermoresistible__bu --------AGLGGRGX----------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
Mb1476c|M.bovis_AF2122/97 -------DGGAGGNG-----------------------------------
Rv1441c|M.tuberculosis_H37Rv -------DGGAGGTG-----------------------------------
MMAR_2596|M.marinum_M -------AGGAGGQG-----------------------------------
MUL_3292|M.ulcerans_Agy99 -------IGGIGASGS----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --AINESLGGSGSVGG----------------------------------
MAV_4827|M.avium_104 QPPSPPQVGGTVPQSP----------------------------------
TH_3810|M.thermoresistible__bu ----------------------------------------------XXXG
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
Mb1476c|M.bovis_AF2122/97 ---------GGSSMIG--------------GKGG------------TGGN
Rv1441c|M.tuberculosis_H37Rv ---------GGSSMIG--------------GKGG------------TGGN
MMAR_2596|M.marinum_M -------GAGRGSEIG-------------GGAGG------------AGSV
MUL_3292|M.ulcerans_Agy99 --FGAPSGQGGNGGIGGAAGLF-----GQGGAGGNGGQGGGDDFALSGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---STAVGGGAHTGVGGGVSTG-------VGVGSHVGGGISESLGGSGSV
MAV_4827|M.avium_104 ------PQHQTPPGEGTPPKPD--------GPGNYGG-----GHVPTPGA
TH_3810|M.thermoresistible__bu GGVGAAVRSGNGVFSGGGGTPSAG--------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
Mb1476c|M.bovis_AF2122/97 GGVGGTGGASALTIGNGSSAGAGG--------------------------
Rv1441c|M.tuberculosis_H37Rv GGVGGTGGASALTIGNGSSAGAGG--------------------------
MMAR_2596|M.marinum_M GGAGGAGGTGAWLFGNGGSGGAGG--------------------------
MUL_3292|M.ulcerans_Agy99 GGAGGAGGHGGQLYGDGGGGGAGG--------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSTAVGGGAHTGVGGGVSTGVGVG-------------------------
MAV_4827|M.avium_104 GGSGGSGGGHVPTPGAGGSGGSGGG-------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
Mb1476c|M.bovis_AF2122/97 --------AGG------AGGTGGTG---------------------GYIE
Rv1441c|M.tuberculosis_H37Rv --------AGG------AGGTGGTG---------------------GYIE
MMAR_2596|M.marinum_M --------AGG---------MGGNG---------------------GNG-
MUL_3292|M.ulcerans_Agy99 --------MGGSVDIAESGVTGGRG---------------------GSGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------SHVGGGISESLGGSGSVG---------------------GSTA
MAV_4827|M.avium_104 --------------HVPTPGTGGPG---------------------GTGG
TH_3810|M.thermoresistible__bu FGVPTTIQFPAG--------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
Mb1476c|M.bovis_AF2122/97 SLDGKGQAGNGG-------------------------NGGNGAAGGAGGG
Rv1441c|M.tuberculosis_H37Rv SLDGKGQAGNGG-------------------------NGGNGAAGGAGGG
MMAR_2596|M.marinum_M VGN-PGDGGDGG-------------------------GGGAGASGGDGG-
MUL_3292|M.ulcerans_Agy99 VGGGAGLWGAGG-------------------------QGGDGAQGGDGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGAHTGVGGG------------------------VNTGVGVGSHVGGG
MAV_4827|M.avium_104 SGGGHVPTPGAG-------------------------TPGGSGGGHLPFP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
Mb1476c|M.bovis_AF2122/97 G----TGAGG--------NGGAG---------------------------
Rv1441c|M.tuberculosis_H37Rv G----TGAGG--------NGGAG---------------------------
MMAR_2596|M.marinum_M ---WLWGSGG--------NGGSGGAGRDG----ADGGVDPKSGRTG----
MUL_3292|M.ulcerans_Agy99 GVDTTTGAGG--------DGGAGAGGGTSGFLYGNGGAGGAGGHGGG---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ISESLGGSGS--------VGGSTAVGGGAHTSAINDALG-----------
MAV_4827|M.avium_104 GAGSTPGGSG---------GGHLPTPG-----------------------
TH_3810|M.thermoresistible__bu -------SCTSRAVSREGIMPSSR--------AASARAGAACASSTSRSR
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
Mb1476c|M.bovis_AF2122/97 ------GNGGDGGPSQGGGNPGFG--------GDGGTGGPGG---VGVPD
Rv1441c|M.tuberculosis_H37Rv ------GNGGDGGPSQGGGNPGFG--------GDGGTGGPGG---VGVPD
MMAR_2596|M.marinum_M ----ATGDGGDGGDGGDGGDAALV--------GNGGNGGAGG---SGVTD
MUL_3292|M.ulcerans_Agy99 ----GPGMGGDGGDGGDGGRAQLI--------GTGGNGGAGGTAAPGGTD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------GSGSVGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSSM
MAV_4827|M.avium_104 -----AGTPGGGLGGFGGGHAPAP--------GGGLGGGGGHAPAPGGGL
TH_3810|M.thermoresistible__bu RSFCCSRA--------------------------
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD-------
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD--------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP-------
Mb1476c|M.bovis_AF2122/97 GIGGANG-------AQGKHG--------------
Rv1441c|M.tuberculosis_H37Rv GIGGANG-------AQGKHG--------------
MMAR_2596|M.marinum_M GAGGRGGAGGGLYGTPGMSG--------------
MUL_3292|M.ulcerans_Agy99 GTAGAAGKGGVLFGTDGATG--------------
MLBr_01183|M.leprae_Br4923 ----------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH
MAV_4827|M.avium_104 GGFGGGHSGGGLGGLGGGHK--------------