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SYVIAAPELLAGAATDLAGLGSTLQIANRAAAATITGVPAAGADDVSAALAAVFSGHALDYQALSAQMAG VHQRFVQALTASGSSYAAAEAANTNPLQGVEEHLLGVLNSPTQALLGRPLIGDGAAGAPGQDGGDGGLLL GNGGAGGTGSAANPDGGNGGAAGLIGNGGAGGTGYSPTTGSGAVGGNGGAGGTGGWLYGSGGSGGIGGVG GSGTIGAPSGHGGSGGLGGGTGLFGQGGAGGNGGQGGGENFASTAGAGGPAGTGGHGGWLYGNGGAGGIG GAGGVVGSSEGGVDGGVGGSGGSGGATGLLGNGGAGGTGGQGGDGGRGFDGSLGAGGAGGTGAVGGSGGW LVGDGGTGGDGGQGGGGHLGGAFAGGGGDGGAGAVGGTGGWLLGDGGAGGNGGDGGDGGAASGFAGDGGR GGQGAVGGASGWLLGNGGAGGDGGAGGEGGDSSGGAASAGGDGGAGGAGGAGANGGLLIGHGGAGGGGGT GGNGHGRPIGSGGAGGDGGGGGTGGWLYGNGGHGGTGATGGSGRHSGASGDGGDGGDAQAIGDGGAGGSG GAGGAGGSGGLLFGAPGAHG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0837 | - | - | 100% (581) | PE-PGRS family protein |
| M. marinum M | MMAR_2053 | - | 0.0 | 53.37% (742) | PE-PGRS family protein |
| M. marinum M | MMAR_4223 | - | 0.0 | 56.52% (621) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 1e-172 | 52.44% (675) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-113 | 49.28% (483) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 1e-173 | 52.19% (684) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-14 | 42.71% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-49 | 31.09% (534) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 6e-23 | 43.53% (170) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 8e-92 | 41.90% (599) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 5e-42 | 40.14% (294) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4581 | - | 0.0 | 92.25% (581) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-109 | 49.02% (461) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0837|M.marinum_M ----------------------------------MSYVIAAPELLAGAAT
MUL_4581|M.ulcerans_Agy99 ----------------------------------MSYVIAAPELLAGAAT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mb1121|M.bovis_AF2122/97 ----------------------------------MSFVIAAPEALVAVAS
Rv1091|M.tuberculosis_H37Rv ----------------------------------MSFVIAAPEALVAVAS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------MSIIDFILNLFR
MAV_4827|M.avium_104 ------------------------------MNIVLGVSMAPSSIQMVVLE
MMAR_0837|M.marinum_M DLAGLGSTLQIANRAAAATITGVPAAGADDVSAALAAVFSGHALDYQALS
MUL_4581|M.ulcerans_Agy99 DLAGLGSTLQIANRAAAATITGVPAAGADDVSAALAAVFSGHALDYQALS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mb1121|M.bovis_AF2122/97 DLAGIGSALAEANAAALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVS
Rv1091|M.tuberculosis_H37Rv DLAGIGSALAEANAAALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQW
MAV_4827|M.avium_104 GEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLS
MMAR_0837|M.marinum_M --------------------------AQMAGVHQRFVQALTASGSSYAAA
MUL_4581|M.ulcerans_Agy99 --------------------------AQMAGVHQRFVQALTASGSSYAAA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mb1121|M.bovis_AF2122/97 --------------------------AQASAFHAQFVQALTGGGGAYAAA
Rv1091|M.tuberculosis_H37Rv --------------------------AQASAFHAQFVQALTGGGGAYAAA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VN------------------------------TGNPIHDLSGNLQNYYAA
MAV_4827|M.avium_104 ------------------------------------SIGVTWTDQLEAAA
MMAR_0837|M.marinum_M EAAN--------------------------------TNPLQGVEEHLLGV
MUL_4581|M.ulcerans_Agy99 EAAN--------------------------------TNPLQGVEEHLLGV
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mb1121|M.bovis_AF2122/97 EAAN--------------------------------VSAAQSTDQRLLDL
Rv1091|M.tuberculosis_H37Rv EAAN--------------------------------VSAAQSTDQRLLDL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 QPDG-----------------------------------PSILSPSLLSP
MAV_4827|M.avium_104 LR--------------------------------------DALAARRIDN
MMAR_0837|M.marinum_M LN--------------------SPTQALLG--------RPLIGDGAAG-A
MUL_4581|M.ulcerans_Agy99 LN--------------------SPTQALLG--------RPLIRDGAAG-A
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mb1121|M.bovis_AF2122/97 IN--------------------GPTQALLG--------RPLIGDGANG-G
Rv1091|M.tuberculosis_H37Rv IN--------------------GPTQALLG--------RPLIGDGANG-G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 RD------------------------------------NDFLSHNDTDFA
MAV_4827|M.avium_104 VMLVS---------------------------------AFLAAAALAQNV
MMAR_0837|M.marinum_M PGQDGGDGGLLLGNGGAGGTGSAANPDGGNGGAAGLIGNGGAGGTGYSPT
MUL_4581|M.ulcerans_Agy99 PGQDGGDGGLLLGNGGAG-------------------------GTGYSPT
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKL-----SRGGD
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG-------NGGN
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG-------NGGN
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG--------NGGN
Mb1121|M.bovis_AF2122/97 PGQDGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIG--------NGGA
Rv1091|M.tuberculosis_H37Rv PGQDGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIG--------NGGA
MLBr_01183|M.leprae_Br4923 --------MPLFLN-----------------AEPQALT--------AAAN
MAB_4284c|M.abscessus_ATCC_199 SHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNR-------DTTA
MAV_4827|M.avium_104 GGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIR-------AES
MMAR_0837|M.marinum_M TGSGAVGGNGGAGGTGG--WLYGSGGSGGIGGVG----------------
MUL_4581|M.ulcerans_Agy99 TGSGAVGGDGGAGGTGG--WLYGSGGSGGIGGVG----------------
TH_3810|M.thermoresistible__bu GGDGGLGGNGGHGGGTGIISLLSLAGNGGNGGNGYR--------------
Mflv_5091|M.gilvum_PYR-GCK GGNGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVA
Mvan_1264|M.vanbaalenii_PYR-1 GGNGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVA
MSMEG_0868|M.smegmatis_MC2_155 GGVGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTG
Mb1121|M.bovis_AF2122/97 GGGGGAGAAGGNGGAGG--WLYGNGGAGGAGG------------------
Rv1091|M.tuberculosis_H37Rv GGGGGAGAAGGNGGAGG--WLYGNGGAGGAGG------------------
MLBr_01183|M.leprae_Br4923 TLEGLSAATVASNAAAA--QLTTEIAPPAADDVS----------------
MAB_4284c|M.abscessus_ATCC_199 IGDGAVAVGGSNSGPIAS----GQGSTAVNGDVR----------------
MAV_4827|M.avium_104 YGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVS
. . .
MMAR_0837|M.marinum_M --GSGTIGAPSGHGGSGGLGGGTGLFG--QGGAGGNGGQGGGEN------
MUL_4581|M.ulcerans_Agy99 --GSGTIGAPSGHGGSCGLGGGTGLFG--QGGAGGNGGQGGGEN------
TH_3810|M.thermoresistible__bu --TTDNNALDGGHGGNGGNVGFFSLFN--LGGAGGWGGSGVDG-------
Mflv_5091|M.gilvum_PYR-GCK GATGATGVTSGVVGGNGEDAVGYGATG--AAGAAGAAGAAGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 GATGATGVTSNVTGGNGADAVGYGATG--AAGAAGAAGAAGKAG------
MSMEG_0868|M.smegmatis_MC2_155 GTGGGTGGTGGIGGTGGGLFGLLGHSG--STGAAGAAGNGGDGGNGGFGY
Mb1121|M.bovis_AF2122/97 -----TSVIPGVAGGNGGAGGSAGLWG--TGGAGGDGGNGRSGP------
Rv1091|M.tuberculosis_H37Rv -----TSVIPGVAGGNGGAGGSAGLWG--TGGAGGDGGNGRSGP------
MLBr_01183|M.leprae_Br4923 ------ILLAHFFSGHGRQYQAHASQG--ATNHQDLIQSLLTSS------
MAB_4284c|M.abscessus_ATCC_199 ----DSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKS------
MAV_4827|M.avium_104 VAEEPETALARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLP---
. .
MMAR_0837|M.marinum_M ---------FASTAGAGGPAGTGGHGG--WLYGNGGAGGIGGAG------
MUL_4581|M.ulcerans_Agy99 ---------FASTAGAGGPAGTGGHGG--WLYGNGGAGGIGGAG------
TH_3810|M.thermoresistible__bu ---------VDVVGGNP-DGGTPGAHG--ESHTPGVYTDR----------
Mflv_5091|M.gilvum_PYR-GCK --------AVGSAGAAG-EAGETGTWG--NAGLPGKAGDAGGAG------
Mvan_1264|M.vanbaalenii_PYR-1 --------AVGSAGTAG-SAGAPGVWG--NAGLPGAAGAAGGAG------
MSMEG_0868|M.smegmatis_MC2_155 VLIAGPNVTVGSETRGG-TGGAGGTGGQSTAAGPGKGGGGGGGGGGAILI
Mb1121|M.bovis_AF2122/97 ---------VNVAGSAGGNGGAGGAAGLFGDAGAGGNGGKGGAG------
Rv1091|M.tuberculosis_H37Rv ---------VNVAGSAGGNGGAGGAAGLFGDAGAGGNGGKGGAG------
MLBr_01183|M.leprae_Br4923 ------------SAYAGTETANHDSL------------------------
MAB_4284c|M.abscessus_ATCC_199 -------VTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIG-----
MAV_4827|M.avium_104 -----DYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLP------
.
MMAR_0837|M.marinum_M --------------------------------------------------
MUL_4581|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------AVGAAGAAG------TVGTAGATGGTG-------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------AIGTAGVAG------AAGTAGATGGTG-------------
MSMEG_0868|M.smegmatis_MC2_155 GANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEG
Mb1121|M.bovis_AF2122/97 ------------GAAFSIN---------FTAGDGGAG-------------
Rv1091|M.tuberculosis_H37Rv ------------GAAFSIN---------FTAGDGGAG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0837|M.marinum_M -GVVGSSEGGVDGGVGGSGGSGG---------------------------
MUL_4581|M.ulcerans_Agy99 -GVVGSSEGGVDGGVGGSGGSGG---------------------------
TH_3810|M.thermoresistible__bu --QGEDGEDGTGTGIGGRGGNG----------------------------
Mflv_5091|M.gilvum_PYR-GCK --TGANGGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTT
Mvan_1264|M.vanbaalenii_PYR-1 --VGGNGGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVT
MSMEG_0868|M.smegmatis_MC2_155 TATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGT
Mb1121|M.bovis_AF2122/97 -GAGGSGGHALLWGAGGAGGNGG-------------SGGTGGAGGSTAGA
Rv1091|M.tuberculosis_H37Rv -GAGGSGGHALLWGAGGAGGNGG-------------SGGTGGAGGSTAGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --SHNQANIGTSTSAGGSAAVGG-------------NAGLAGNAGLAGNA
MAV_4827|M.avium_104 --EDSEPRRRPVLLVGSGLAVVG------------ISAVLALEIALAIGI
MMAR_0837|M.marinum_M ----------------ATGLLGNGGAGGTGGQGGDGGRG----FDGSLG-
MUL_4581|M.ulcerans_Agy99 ----------------ATGLLGNSGAGGTGGQGGGGGRG----FDGSLG-
TH_3810|M.thermoresistible__bu --------------------------GSSSGTHPMAEDG-----------
Mflv_5091|M.gilvum_PYR-GCK GGAGGVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-
Mvan_1264|M.vanbaalenii_PYR-1 GGVGGIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-
MSMEG_0868|M.smegmatis_MC2_155 GGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGP
Mb1121|M.bovis_AF2122/97 GGNGGAGGG-GGTGGLLFGNGGAGGHGAAAGNGLAAGNGVSSSGGGGAG-
Rv1091|M.tuberculosis_H37Rv GGNGGAGGG-GGTGGLLFGNGGAGGHGAAAGNGLAAGNGVSSSGGGGAG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG-
MAV_4827|M.avium_104 RTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKP-
MMAR_0837|M.marinum_M -------------AGGAGGTGAVGGSGGWLVG------------------
MUL_4581|M.ulcerans_Agy99 -------------AGGAEGTGAVGGSGGWLVG------------------
TH_3810|M.thermoresistible__bu -------------EHVKALDGRPGLDGG----------------------
Mflv_5091|M.gilvum_PYR-GCK ------------LQGGKGGDGGAGGKGGDADSMGS---------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------LQGGQGGDGGTGGTGGDATSMGE---------------
MSMEG_0868|M.smegmatis_MC2_155 TTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGN
Mb1121|M.bovis_AF2122/97 ------------GTGGAGGDGGAGGAGGNARLWGVG--------------
Rv1091|M.tuberculosis_H37Rv ------------GTGGAGGDGGAGGAGGNARLWGVG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------LAGNAGLAGNAGLAGNAGLAG-----------------
MAV_4827|M.avium_104 ------------LSPPVAAPLPAAPPPAAPPLP-----------------
MMAR_0837|M.marinum_M ------DGGTGGDGGQGGGGHLGG-------------------AFAGG--
MUL_4581|M.ulcerans_Agy99 ------DGGTGGDGGQGGGGHLGG-------------------AFAGG--
TH_3810|M.thermoresistible__bu ------NGSHGGNGGHGGRGGFLG--------------------------
Mflv_5091|M.gilvum_PYR-GCK ---AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-
Mvan_1264|M.vanbaalenii_PYR-1 ---AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-
MSMEG_0868|M.smegmatis_MC2_155 GGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNG
Mb1121|M.bovis_AF2122/97 -----GAGGAGGDGGAGGAGGKGG----------------SGLSGNAN--
Rv1091|M.tuberculosis_H37Rv -----GAGGAGGDGGAGGAGGKGG----------------SGLSGNAN--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------NAGLAGNAGLAGNAGLAG------------------NAGLAGN-
MAV_4827|M.avium_104 -----EAPPIPAAPPVVPVPVVVP--------------------------
MMAR_0837|M.marinum_M ---------------------GGDGGAGAVGGTGGWLLGDGGAGG-----
MUL_4581|M.ulcerans_Agy99 ---------------------GGDGGAGAVGGTGGWLLGDGGAGG-----
TH_3810|M.thermoresistible__bu --------------------IGGSGGWGGHGGNGGDTDADGGNGG-----
Mflv_5091|M.gilvum_PYR-GCK ---------------------GGTGGAGGAGGTGG-TGGAGGTGG-----
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------GGTGGNGGNGGTGG-TGGNGGTGG-----
MSMEG_0868|M.smegmatis_MC2_155 WVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVW
Mb1121|M.bovis_AF2122/97 ---------------------GGAGGDSGRGGTGG-AGGEGGAAG-----
Rv1091|M.tuberculosis_H37Rv ---------------------GGAGGDSGRGGTGG-AGGEGGAAG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------AGLAGNAGLAGNAGLAGNAAVAGN-----
MAV_4827|M.avium_104 ---------------------PVPVPVPVRIPVPDPVSPPQLLAP-----
MMAR_0837|M.marinum_M -------------------------------------------------N
MUL_4581|M.ulcerans_Agy99 -------------------------------------------------D
TH_3810|M.thermoresistible__bu -------------------------------------------------D
Mflv_5091|M.gilvum_PYR-GCK ------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGT
MSMEG_0868|M.smegmatis_MC2_155 KANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGT
Mb1121|M.bovis_AF2122/97 -----------LLVGTGGHGGDGGAGGAAVKGGDGGAAAGTGIA----GA
Rv1091|M.tuberculosis_H37Rv -----------LLVGTGGHGGDGGAGGAAVKGGDGGAAAGTGIA----GA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------AAVAGNAAVAGNAAVGGVLNTGVSGAIGGSSHVG--GAIN
MAV_4827|M.avium_104 ------------PRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTP
MMAR_0837|M.marinum_M GGDGGDGG--AASGFAGDGGRG----------------------------
MUL_4581|M.ulcerans_Agy99 GGDGGDGG--AASGFAGDGGQG----------------------------
TH_3810|M.thermoresistible__bu GGNGGSAGRGGTGGLRGVFGIN----------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------
MSMEG_0868|M.smegmatis_MC2_155 GGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHT
Mb1121|M.bovis_AF2122/97 GGRGGAGGSGGSGGDGGGGAAG----PAGWLFGDGGAGGNG---------
Rv1091|M.tuberculosis_H37Rv GGRGGAGGSGGSGGDGGGGAAG----PAGWLFGDGGAGGNG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESLGGSGSVGGSTAVGGGAHTG----------------------------
MAV_4827|M.avium_104 PGEGTPPKPDGPGNYGGGHVPTP---------------------------
MMAR_0837|M.marinum_M ---GQGAVGGAS---------------------------GWLLGNGGAGG
MUL_4581|M.ulcerans_Agy99 ---GQGAVGGAS---------------------------GWLLGNGGAGG
TH_3810|M.thermoresistible__bu -----GGNGRAG-----------------------------LGGRGXXXX
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG
MSMEG_0868|M.smegmatis_MC2_155 GAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGG
Mb1121|M.bovis_AF2122/97 ---GAAAAGGAG--------------GQAGGGGG----NGGNGGNGGNGG
Rv1091|M.tuberculosis_H37Rv ---GAAAAGGAG--------------GQAGGGGG----NGGNGGNGGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --VGGGVSTGVG--------------------------VGSHVGGGISES
MAV_4827|M.avium_104 ---GAGGSGGSG------------------------------GGHVPTPG
MMAR_0837|M.marinum_M -----------------DGGAGGEGG------------------------
MUL_4581|M.ulcerans_Agy99 -----------------DGGAGGEGG------------------------
TH_3810|M.thermoresistible__bu -----------------GGGVG----------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------------TGGTGGQGG-LGGGGGTG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------TGGTGGQGG-LGGVGGTG---------------
MSMEG_0868|M.smegmatis_MC2_155 EALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANP
Mb1121|M.bovis_AF2122/97 -----------------NGGNGATGGWLYGNGGAG---------------
Rv1091|M.tuberculosis_H37Rv -----------------NGGNGATGGWLYGNGGAG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------LGGSGSVGG------------------------
MAV_4827|M.avium_104 -----------------AGGSGGSGG------------------------
MMAR_0837|M.marinum_M ---------------------------------------DSSGGAASAGG
MUL_4581|M.ulcerans_Agy99 ---------------------------------------DSSGGAASAGG
TH_3810|M.thermoresistible__bu -----------------------------------------AAVRSGNGV
Mflv_5091|M.gilvum_PYR-GCK --------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGG
Mvan_1264|M.vanbaalenii_PYR-1 --------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGG
MSMEG_0868|M.smegmatis_MC2_155 QASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGI
Mb1121|M.bovis_AF2122/97 --------GQGATAGAGGAGANGVSSTNGG----------GNGGIGGTGG
Rv1091|M.tuberculosis_H37Rv --------GQGATAGAGGAGANGVSSTNGGGTG-------GNGGIGGTGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------STAVGGGA
MAV_4827|M.avium_104 ----------------------------------------------GHVP
MMAR_0837|M.marinum_M DGGAGGAGGAGANGGLLIGHGGAGGGGGTGGNGHGRPIGSGGAGGDGG--
MUL_4581|M.ulcerans_Agy99 DGGAGGAGGAGANGGLLIGHGGAGGGG-TGGNGHGRPIGSGGAGGDGG--
TH_3810|M.thermoresistible__bu FSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREGIMPSSRAAS-------
Mflv_5091|M.gilvum_PYR-GCK LGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG--
Mvan_1264|M.vanbaalenii_PYR-1 LGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG--
MSMEG_0868|M.smegmatis_MC2_155 DGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPS
Mb1121|M.bovis_AF2122/97 SGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGFISSDGGAGGDGG--
Rv1091|M.tuberculosis_H37Rv SGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGFISSDGGAGGDGG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGG--
MAV_4827|M.avium_104 TPGTGGPGGTGGSGGGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGG--
MMAR_0837|M.marinum_M --------GGGTGGWLYGNGGHGGTGATGGS---------------GRHS
MUL_4581|M.ulcerans_Agy99 --------DGGTGGWLYGNGGHGGTGATGGS---------------GRHS
TH_3810|M.thermoresistible__bu -------ARAGAACASSTSRSRRSFCCSRA--------------------
Mflv_5091|M.gilvum_PYR-GCK --GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-AT
Mvan_1264|M.vanbaalenii_PYR-1 --GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-AT
MSMEG_0868|M.smegmatis_MC2_155 WVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVAT
Mb1121|M.bovis_AF2122/97 --DGGNGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNG---GAGNGGGTD
Rv1091|M.tuberculosis_H37Rv --DGGNGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNG---GAGNGGGTD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --GVNTGVGVGSHVGGGISESLGGSGSVGGSTAVG------GGAHTSAIN
MAV_4827|M.avium_104 -------GHLPTPGAGTPGGGLGGFGGGHAPAPGG---------------
MMAR_0837|M.marinum_M GASGDGGDGGDAQAIGD---------------------------------
MUL_4581|M.ulcerans_Agy99 GASGDGGDGGDAQAIGD---------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGA
Mvan_1264|M.vanbaalenii_PYR-1 GASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGA
MSMEG_0868|M.smegmatis_MC2_155 GNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGG
Mb1121|M.bovis_AF2122/97 GNGGNGGSGGGAGSGGDGGGAGG-----------NGAWLFGNGGAGGGGG
Rv1091|M.tuberculosis_H37Rv GNGGNGGSGGGAGSGGDGGGAGG-----------NGAWLFGNGGAGGGGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DALGGSGSVGGSTAVGGG------------------AHTSAINESMNSSI
MAV_4827|M.avium_104 ---GLGGGGGHAPAPGG---------------------------------
MMAR_0837|M.marinum_M --------------------------------------------------
MUL_4581|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK NGSQGAAG--KAGATGTTGATG--------AAGEDGDAGSGGSG-INGGA
Mvan_1264|M.vanbaalenii_PYR-1 NGSQGAAG--KAGATGTTGATG--------AAGDAGDPGSEAVD-INGGA
MSMEG_0868|M.smegmatis_MC2_155 NGGKGADG--WVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGD
Mb1121|M.bovis_AF2122/97 KGGNGAGGGLGGGSFGLPGLNG--------SGGDGGDGGNGAPGGVLYGN
Rv1091|M.tuberculosis_H37Rv KGGNGAGGGLGGGSFGLPGLNG--------SGGDGGDGGNGAPGGVLYGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NASHSSS-------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0837|M.marinum_M -------------------------------------------GGAGGSG
MUL_4581|M.ulcerans_Agy99 -------------------------------------------GGAGGSG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGAGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGG
Mvan_1264|M.vanbaalenii_PYR-1 GGAGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNG
Mb1121|M.bovis_AF2122/97 GGAGGQGS-----SGGIGGPGATGGAGGKGGDGGDAQLIGD--GGNGGNG
Rv1091|M.tuberculosis_H37Rv GGAGGQGS-----SGGIGGPGATGGAGGKGGDGGDAQLIGD--GGNGGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------MNESFGS
MAV_4827|M.avium_104 ----------------------------------------------GLGG
MMAR_0837|M.marinum_M GAGGAGGSGGLLFGAPGAHG-------------------
MUL_4581|M.ulcerans_Agy99 ---------GLLFGAPGAHG-------------------
TH_3810|M.thermoresistible__bu ---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
Mb1121|M.bovis_AF2122/97 GAGGTG-GTPGPGGPGGSGGLGG--LLFGQTGTAGVSP-
Rv1091|M.tuberculosis_H37Rv GAGGTG-GTPGPGGPGGSGGLGG--LLFGQTGTAGVSP-
MLBr_01183|M.leprae_Br4923 ---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MAV_4827|M.avium_104 FGGGHSGGGLGGLGGGHK---------------------