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PHPILATAMAVGIAATAGAGALGDAPPTVNVTANKHVSATRLTAVVTPNALYSAAPASDVVVLGAHGSLA VGEPRGVPQAGALAGASRAVPGGLELSTGLATSRVHPLPERVNTDIEMVSAPTTSGPALRLGRATTPSVG STGPAGAAAPGLFSLLIGNGDEPGENGGWLIGNGADGGPGQDGGRGGLLFGNGGRGGDALTSGGPAGRGG DAGLFGNGGDGGTGFVSSAAGTNAASGGTGGAGGNGGLLMGDGGKGGTGGRAISAEGPANGGNGGRGGNA GVLGGDAGGGGDGGRGYSEKGPASGGAGGAGAAASTVGNGGSGGKGGSAQGAGSANGGAGGSGGAGGFVS GDGGAGGGGGTALSAAGTGSGGSGGDGGNARGAGGGGRGGVGALGQSKDARGFGGVGGAGGRSGVTGTGG AGGAGGSGVSDTLDAAGGSGGDGGDGSRGGIGGTGGAAHSKSGNAQGGFAGDGGTGSRGSGGDGGDGGIG TSTTGKGRGGNGGNGGGGIRAAPVGKAAKARRAAAVAEATAPAPDGVVSLGPAYAQSRSATNALCCNEFS CAVTNSSEW*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3867 | - | - | 100% (570) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_3856 | - | e-101 | 44.02% (527) | hypothetical protein Mvan_3856 |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 5e-81 | 37.77% (564) | triple helix repeat-containing collagen |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 1e-85 | 40.39% (557) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 4e-79 | 39.71% (549) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 1e-85 | 40.39% (557) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 2e-07 | 32.39% (142) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_4284c | - | 3e-39 | 34.66% (401) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_2596 | - | 8e-84 | 49.09% (383) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 3e-21 | 42.35% (170) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_3202 | - | 7e-69 | 36.94% (536) | hypothetical protein MSMEG_3202 |
M. thermoresistible (build 8) | TH_3810 | - | 1e-40 | 36.49% (359) | PUTATIVE - |
M. ulcerans Agy99 | MUL_3507 | - | 9e-81 | 40.18% (565) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_3867|M.vanbaalenii_PYR-1 ----------------MPHPILATAMAVGIAATAGAGALGDAPPTVN--V MSMEG_3202|M.smegmatis_MC2_155 ---------------MTKHQRLTSAVAASIVATAGVAVSQAPAPASTGTP Mb1121|M.bovis_AF2122/97 -------MSF---VIAAPEALVAVASDLAGIGSALAEANAAALAPTTALL Rv1091|M.tuberculosis_H37Rv -------MSF---VIAAPEALVAVASDLAGIGSALAEANAAALAPTTALL MMAR_2596|M.marinum_M -------MSY---LTVAPEALSAATSDAAEIGSALAAANAAAAARTAGLL MUL_3507|M.ulcerans_Agy99 -------MSF---VSVTQEALAAAASDVGVIGSSLQAANMSVAAPTAGVL Mflv_5091|M.gilvum_PYR-GCK ------MVTFGGGATPTPTSLGAAAVDLSGTSCGLICNGQDGTGQNGGIL TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVV MAV_4827|M.avium_104 -------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAA MLBr_01556|M.leprae_Br4923 MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRES Mvan_3867|M.vanbaalenii_PYR-1 TANK-----------HVSATRLTAVVTPNA--------LYSAAPASDVVV MSMEG_3202|M.smegmatis_MC2_155 TAHQ-----------TPTSTSTPRWLTVTS--------TPEGAPATPNAL Mb1121|M.bovis_AF2122/97 AAGA-----------DEVSAAIAALFGAHG-------QAYQTVSAQASAF Rv1091|M.tuberculosis_H37Rv AAGA-----------DEVSAAIAALFGAHG-------QAYQTVSAQASAF MMAR_2596|M.marinum_M SAGG-----------DEVSAAIAAVFSAHG-------VQYQAISAQMAQF MUL_3507|M.ulcerans_Agy99 AAGA-----------DEVSVAMAALFSGHG-------QAYQTLSAQANAF Mflv_5091|M.gilvum_PYR-GCK FGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGGGNGGNGGNAGA TH_3810|M.thermoresistible__bu -VDG-----------DGGSGGRTGLFSKLS-------------------- MAB_4284c|M.abscessus_ATCC_199 AES------------VASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDG MAV_4827|M.avium_104 TASAP----------DRVISAILGTREGAADAG---LQLSSIGVTWTDQL MLBr_01556|M.leprae_Br4923 FGGIKPAADKG-AEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAA Mvan_3867|M.vanbaalenii_PYR-1 LGAHGSLAVGEPRG----VPQAGALAGASRAVPGGLELSTGLATSRVHPL MSMEG_3202|M.smegmatis_MC2_155 YGAI--LPSTSPGS----VTSTG--SGIGHREPG---ISGSPAFTAVRAV Mb1121|M.bovis_AF2122/97 HAQFVQALTGGGG------AYAAAEAANVSAAQSTDQRLLDLINGPTQAL Rv1091|M.tuberculosis_H37Rv HAQFVQALTGGGG------AYAAAEAANVSAAQSTDQRLLDLINGPTQAL MMAR_2596|M.marinum_M HRQFAQALSAANR------SYALAEAANASPLQAIEQQLLAAINAPTQTL MUL_3507|M.ulcerans_Agy99 HAQFLQALTNAGG------AYAAAEVANLSPLQGVEQGVLGVVNAPAQAL Mflv_5091|M.gilvum_PYR-GCK FALFGNGGNGGNGGVGVVGATGAVGAPGVAGATGATGVTSGVVGGNGEDA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 PSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGP MAV_4827|M.avium_104 EAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPD MLBr_01556|M.leprae_Br4923 PVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPA Mvan_3867|M.vanbaalenii_PYR-1 -PERVNTDIEMVSAPTTSGPALRLGR----------ATTPSVG------S MSMEG_3202|M.smegmatis_MC2_155 RPGSSTARLVFAPKTSTSGTALTVTP----------IAVGMVGNAKVTVA Mb1121|M.bovis_AF2122/97 LGRPLIGDGANG-GPGQDGGPGGL-------------LYGNGGNGG--TS Rv1091|M.tuberculosis_H37Rv LGRPLIGDGANG-GPGQDGGPGGL-------------LYGNGGNGG--TS MMAR_2596|M.marinum_M LGRPLIGNGADG-APGQNGAAGGL-------------LWGNGGAGG--AG MUL_3507|M.ulcerans_Agy99 LGRPLIGDGAAGTAASPNGGAGGL-------------LYGNGGAGYSYTS Mflv_5091|M.gilvum_PYR-GCK VGYGATGAAGAAGAAGAAGAAGAVGSAGAAGEAGETGTWGNAGLPGKAGD TH_3810|M.thermoresistible__bu --------------RGGDGGDGGLG--------------GNGGHGG---- MAB_4284c|M.abscessus_ATCC_199 LLDLSFGDLQFGNRDTTAIGDGAVA-------------VGGSNSGPIASG MAV_4827|M.avium_104 TATLAVVETSDGSIPDVYKQQIRAES------------YGDAAGQLSAMV MLBr_01556|M.leprae_Br4923 APHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPR Mvan_3867|M.vanbaalenii_PYR-1 TGPAGAAAPGLFSLLIGNGDEPGENGG----------------------- MSMEG_3202|M.smegmatis_MC2_155 VDSSGRPMIGPGGWLIGNGIEPGQNGG----------------------- Mb1121|M.bovis_AF2122/97 TTAGVAGGNGGAAGLIGNGGAGGGGGAGAAGGNGGAGGWLYGNGGAGGAG Rv1091|M.tuberculosis_H37Rv TTAGVAGGNGGAAGLIGNGGAGGGGGAGAAGGNGGAGGWLYGNGGAGGAG MMAR_2596|M.marinum_M TATHTAGGNGGDAGLIGNGGAGGAG------------------------- MUL_3507|M.ulcerans_Agy99 GATAEAGGNGGAAGLIGNGGAGGSGWAGGAGGAGGNGGWLYGNGGAGGLG Mflv_5091|M.gilvum_PYR-GCK AGGAGAVGAAGAAGTVGTAGATGGTGTGANGGAGGVGG-VGGTGAAGAAG TH_3810|M.thermoresistible__bu -----GTGIISLLSLAGNGGNGGNGYR----------------------- MAB_4284c|M.abscessus_ATCC_199 QGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDK MAV_4827|M.avium_104 AGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVS------------ MLBr_01556|M.leprae_Br4923 PSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGGN . Mvan_3867|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 -------------------------------------------------- Mb1121|M.bovis_AF2122/97 GTSVIPGVAGGNGGAGGSAGLWGTGGAGGDGGNGRSGPVNVAGSAGGNGG Rv1091|M.tuberculosis_H37Rv GTSVIPGVAGGNGGAGGSAGLWGTGGAGGDGGNGRSGPVNVAGSAGGNGG MMAR_2596|M.marinum_M -------------------------------------------------- MUL_3507|M.ulcerans_Agy99 G------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK G-----------------------------------------------AG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 S------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 YR------------------------------------------------ Mvan_3867|M.vanbaalenii_PYR-1 ------------------------------WLIGNGADGGPGQDG----- MSMEG_3202|M.smegmatis_MC2_155 ------------------------------LLIGNGADGGPGQKG----- Mb1121|M.bovis_AF2122/97 AGGAAGLFGDAGAGGNGGKGGAGGAAFSINFTAGDGGAGGAGGSGGHALL Rv1091|M.tuberculosis_H37Rv AGGAAGLFGDAGAGGNGGKGGAGGAAFSINFTAGDGGAGGAGGSGGHALL MMAR_2596|M.marinum_M ------------------------------FNAGNGAAGGAGGAG----- MUL_3507|M.ulcerans_Agy99 ------------------------------AAAGDYTAGGVGGAGGNAGL Mflv_5091|M.gilvum_PYR-GCK GLGETGTTGGAGGVGGQGTAGGTGGVGGIGGAGSTGAVGGVGGKGIQGGQ TH_3810|M.thermoresistible__bu ------------------------------TTDNNALDGGHGGNG----- MAB_4284c|M.abscessus_ATCC_199 ------------------------------VTVVDDHSQRNTTNINDSFN MAV_4827|M.avium_104 ----------------------------VAEEPETALARGAALAAANAPL MLBr_01556|M.leprae_Br4923 -GGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGRPGGAPRR Mvan_3867|M.vanbaalenii_PYR-1 -----------------------------------GRGGL--LFGNGGRG MSMEG_3202|M.smegmatis_MC2_155 -----------------------------------GNGGF--LLGNGGRG Mb1121|M.bovis_AF2122/97 WGAGGAGGNGGSGGTGGAGGSTAGAGGNGGAGGGGGTGGL--LFGNGGAG Rv1091|M.tuberculosis_H37Rv WGAGGAGGNGGSGGTGGAGGSTAGAGGNGGAGGGGGTGGL--LFGNGGAG MMAR_2596|M.marinum_M -----------------------------------GHGGW--LYGNGGVG MUL_3507|M.ulcerans_Agy99 WGDGGAGGNGS--ATYDYDQNFSRLGALEGAGGNGGHGGL--LFGNGGGG Mflv_5091|M.gilvum_PYR-GCK GLQGGKGGDGGAGGKGGDADSMGSAGATGGKGGNGGNGGRGGLFGKGGNA TH_3810|M.thermoresistible__bu -----------------------------------GNVGFFSLFNLGGAG MAB_4284c|M.abscessus_ATCC_199 TDRSTNIGSGNTTNTEIGSHNQANIGTSTSAGGSAAVGGNAGLAGNAGLA MAV_4827|M.avium_104 FAS------------------------------STAALAYAQDPGTGAVD MLBr_01556|M.leprae_Br4923 GRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKIDA . . Mvan_3867|M.vanbaalenii_PYR-1 ------------GDALT--SGGPAGRG----------GDAGLFGNGGDGG MSMEG_3202|M.smegmatis_MC2_155 ------------GDGLAGVNGGRAGDG----------GNAGLLGNGGDGG Mb1121|M.bovis_AF2122/97 ------------GHGAAAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGG Rv1091|M.tuberculosis_H37Rv ------------GHGAAAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGG MMAR_2596|M.marinum_M ------------GVGGTGGAGVPAVP---------------TGGDGGAGG MUL_3507|M.ulcerans_Agy99 ------------GDAGANNKFVTAQA----------------TPNGAAGG Mflv_5091|M.gilvum_PYR-GCK ------------GNGADGGTGGAGGAG-------------GTGGTGGAGG TH_3810|M.thermoresistible__bu ------------GWGGSGVDGVDVVGG---------------NPDGGTPG MAB_4284c|M.abscessus_ATCC_199 ------------GNAGLAGNAGLAGNAG----------LAGNAGLAGNAG MAV_4827|M.avium_104 ------------QYSLPDYLYVPVDPEPGD-------DELAYSAVGEEDA MLBr_01556|M.leprae_Br4923 NPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDREL Mvan_3867|M.vanbaalenii_PYR-1 TGFVSSAAGTNAASGGTGGAGGNGGLLMGDGGKGGTGGRAISAEGPANGG MSMEG_3202|M.smegmatis_MC2_155 N----SVGGVEGANGGNAG-------LIGNGGKGGDGSPNVISNG-AHIA Mb1121|M.bovis_AF2122/97 AGGNARLWGV--GGAGGAGGDGGAGGAGGKGGSGLSGNANGGAGGDSGRG Rv1091|M.tuberculosis_H37Rv AGGNARLWGV--GGAGGAGGDGGAGGAGGKGGSGLSGNANGGAGGDSGRG MMAR_2596|M.marinum_M VGGAAGLWGD--GGAGGAGGQGGAGRVGAAGG--------ASSGGTGGHG MUL_3507|M.ulcerans_Agy99 YGGNAGLWGN--GGAGGDGGFGGTATVIGDGGTGGNGGLLSGDGGAGGVG Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGGI--GGAGSTGGTGGTGGTGGTGGTGGTGG-TGGTGGTGGTG TH_3810|M.thermoresistible__bu AHGESHTPGVYTDRQGEDGEDGTGTGIGGRGGNG------GSSSGTHPMA MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGN--AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG MAV_4827|M.avium_104 ESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIR MLBr_01556|M.leprae_Br4923 LEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREA . Mvan_3867|M.vanbaalenii_PYR-1 NGG-----RGGNAGVLGGDAGGGGDGGRGYSEKGPASGGAGGAGAAASTV MSMEG_3202|M.smegmatis_MC2_155 NAG-----RGGN----------GGNGG--------------------LLV Mb1121|M.bovis_AF2122/97 GTG-GAGGEGGAAGLLVGTGGHGGDGGAG--------GAAVKGGDGGAA- Rv1091|M.tuberculosis_H37Rv GTG-GAGGEGGAAGLLVGTGGHGGDGGAG--------GAAVKGGDGGAA- MMAR_2596|M.marinum_M GVG-GIGGSGGAGGWVAGNGGAGGAGGAG--------GMGGMGG------ MUL_3507|M.ulcerans_Agy99 GTG-GIQIYSGGG--IGGVGGIGGNGGAG--------GTSGLIGDGG--- Mflv_5091|M.gilvum_PYR-GCK GKG-GTGGTGGAGG-TGGDGGTGGTGGTG--------GTGGTGGTGGTGG TH_3810|M.thermoresistible__bu EDGEHVKALDGRPGLDGGNGSHGGNGGHG--------GRGGFLG------ MAB_4284c|M.abscessus_ATCC_199 LAG--NAGLAGNAGLAGNAGLAGNAGLAG---------NAGLAGNAG-LA MAV_4827|M.avium_104 TTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLS MLBr_01556|M.leprae_Br4923 EAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGAKATDIA * Mvan_3867|M.vanbaalenii_PYR-1 GNGGSGGKGGSAQGAGSANGGAGGSGGAGGFVSGDGGAGGGGGTALSAAG MSMEG_3202|M.smegmatis_MC2_155 GSGGDGGRGGDGDGEGPETAGSHG---------ADGGNGGAGG------V Mb1121|M.bovis_AF2122/97 AGTGIAGAGGRGGAGGSGGSGGDGGGGAAGPAGWLFGDGGAGGNGGAAAA Rv1091|M.tuberculosis_H37Rv AGTGIAGAGGRGGAGGSGGSGGDGGGGAAGPAGWLFGDGGAGGNGGAAAA MMAR_2596|M.marinum_M TGASIGGGGGTGGAGGTGAAGGDGG--------WLFGDGGSGG------A MUL_3507|M.ulcerans_Agy99 AGGAGGTGGGNAGVGGVGGVGGTGG------AARLFGSGGSGG------I Mflv_5091|M.gilvum_PYR-GCK AGDGTGGTGGTGGTGGQGGQGGQGGTGGTGGQGGLGGGGGTGGQGGTGGT TH_3810|M.thermoresistible__bu -------IGGSGGWGGHGGNGGDTD-----------ADGGNGG------D MAB_4284c|M.abscessus_ATCC_199 GNAAVAGNAAVAGNAAVAGNAAVGGVLNTGVSGAIGGSSHVGG-AINESL MAV_4827|M.avium_104 PPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPV MLBr_01556|M.leprae_Br4923 ILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLT . . Mvan_3867|M.vanbaalenii_PYR-1 TGSGGSGGDG-------------------------------GNARGAGGG MSMEG_3202|M.smegmatis_MC2_155 FGNGGRGGDG-------------------------------GDANNGTVG Mb1121|M.bovis_AF2122/97 GGAGGQAGGG--GGNGGNGGNGGNGGNGGNGATGGWLYGNGGAGGQGATA Rv1091|M.tuberculosis_H37Rv GGAGGQAGGG--GGNGGNGGNGGNGGNGGNGATGGWLYGNGGAGGQGATA MMAR_2596|M.marinum_M GGAGGQGGAG--RGS----------------EIG------GGAGGAGSVG MUL_3507|M.ulcerans_Agy99 GGTGGHSLIN--SGG--------------------------GIGGKGGGG Mflv_5091|M.gilvum_PYR-GCK GGQGGTGGTGGTGGTGGTGGAGGDGGLGGLGGFGG----SGGTGGQGGLG TH_3810|M.thermoresistible__bu GGNGGSAGRG-------------------------------GTGGLRGVF MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGST-----------------------------AVGGGAHTGVG MAV_4827|M.avium_104 PDPVSPPQLLAPPRLS------------------------VPQPVQPPVR MLBr_01556|M.leprae_Br4923 EYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAALDLRANSGME Mvan_3867|M.vanbaalenii_PYR-1 GRGGV--------------------------------------------- MSMEG_3202|M.smegmatis_MC2_155 TRNGN--------------------------------------------- Mb1121|M.bovis_AF2122/97 GAGGAGANGVSSTNGG---GNGGIGGTGGSGGAGGNAGLLGVGGAGGHGA Rv1091|M.tuberculosis_H37Rv GAGGAGANGVSSTNGGGTGGNGGIGGTGGSGGAGGNAGLLGVGGAGGHGA MMAR_2596|M.marinum_M GAG----------------------------------------------- MUL_3507|M.ulcerans_Agy99 GAAG---------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GPGGS--------------------------------------------- TH_3810|M.thermoresistible__bu GING---------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGVSTG-------------------------------------------- MAV_4827|M.avium_104 VPQPPS-------------------------------------------- MLBr_01556|M.leprae_Br4923 AQGVAIEAHLDRGRGP------------------------VATVLVQRGT Mvan_3867|M.vanbaalenii_PYR-1 -----------------------------GALGQSKDARGFGGVGGAGGR MSMEG_3202|M.smegmatis_MC2_155 -----------------------------AAAGK----------GGNGGS Mb1121|M.bovis_AF2122/97 SGGAGDRGGAGGTGFISSDGGAGGDGGDGGNGGAGGTGGLLFGAGGNGGP Rv1091|M.tuberculosis_H37Rv SGGAGDRGGAGGTGFISSDGGAGGDGGDGGNGGAGGTGGLLFGAGGNGGP MMAR_2596|M.marinum_M --------------------------------GAGGTGAWLFGNGGSGGA MUL_3507|M.ulcerans_Agy99 ------------------------------LIGDGGAG----GAGGNGGD Mflv_5091|M.gilvum_PYR-GCK ---------------------TGGAGGAGGQAGTAGKGGLFGGSGSAGKA TH_3810|M.thermoresistible__bu --------------------------------GNGRAG-----LGGRGXX MAB_4284c|M.abscessus_ATCC_199 -----------------------------VGVGSHVGGGISESLGGSGSV MAV_4827|M.avium_104 ----------------------------PPQVGGTVPQSPPQHQTPPGEG MLBr_01556|M.leprae_Br4923 LRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDN . * Mvan_3867|M.vanbaalenii_PYR-1 S-----------------GVTGTGGAGGAGGSGVSDTLDAAGGSGGDGGD MSMEG_3202|M.smegmatis_MC2_155 T-----------------GIG-TGGAGGNGGK-ATGTNAAYGGNGGNGGS Mb1121|M.bovis_AF2122/97 G-----------------GSGGAADIGGNGGAGNGGGTDGNGGNGGSGGG Rv1091|M.tuberculosis_H37Rv G-----------------GSGGAADIGGNGGAGNGGGTDGNGGNGGSGGG MMAR_2596|M.marinum_M G-----------------GAGG---MGGNG--GNGVGNPGDGGDGGGGGA MUL_3507|M.ulcerans_Agy99 GT----------------GAGG---LGGNGASADWIGNGGSGGAGGSGGL Mflv_5091|M.gilvum_PYR-GCK G-----------------ATGAAGASGGKGAQGATGAQGATGAQGATGAT TH_3810|M.thermoresistible__bu X------------------------XGGGVGAAVRSGNGVFSGGGGTPSA MAB_4284c|M.abscessus_ATCC_199 GGST--------------AVGGGAHTGVGGGVSTGVGVGSHVGGGISESL MAV_4827|M.avium_104 TP-----------------PKPDGPGNYGGGHVPTPGAGGSGGSGGGHVP MLBr_01556|M.leprae_Br4923 FLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNL Mvan_3867|M.vanbaalenii_PYR-1 GSRGG-IGGTGGAAHSKSGNAQG--GFAGDGGTGSRGSGGDGGDGGIGTS MSMEG_3202|M.smegmatis_MC2_155 GLAGGGNGGDGGDAQSSSNRARP--GQGGQAGRG--GFGRDGKTGNPGNA Mb1121|M.bovis_AF2122/97 AGSGGDGGGAGGNGAWLFGNGGA----GGGGGKGGNGAGGG-LGGGSFGL Rv1091|M.tuberculosis_H37Rv AGSGGDGGGAGGNGAWLFGNGGA----GGGGGKGGNGAGGG-LGGGSFGL MMAR_2596|M.marinum_M GASGGDGG-------WLWGSGGN----GGSGGAGRDGADGG-VDPK---- MUL_3507|M.ulcerans_Agy99 GAHAGAGG----NGGSLYGNDGS----GGAGGTGASGAGGN-GGGG--GA Mflv_5091|M.gilvum_PYR-GCK GAAGKAGATGAAGAAGAAGSAGTTGAQGSAGTNGANGANGSQGAAGKAGA TH_3810|M.thermoresistible__bu G----------------FGVPTT---IQFPAGSCTSRAVSR--------- MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGGGISESLGGSGSVGG MAV_4827|M.avium_104 TPGAGGSGGSGGGHVPTPGTGGP----GGTGGSGGGHVPTPGAGTPGGSG MLBr_01556|M.leprae_Br4923 ILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASD . Mvan_3867|M.vanbaalenii_PYR-1 TTGKGRGGNGGNGGGGI--------------------------------- MSMEG_3202|M.smegmatis_MC2_155 TDRSATRENVSNRVTG---------------------------------- Mb1121|M.bovis_AF2122/97 PGLNGSGGDGGDGGNGAPG------------------------------- Rv1091|M.tuberculosis_H37Rv PGLNGSGGDGGDGGNGAPG------------------------------- MMAR_2596|M.marinum_M SGRTGATGDGGDGGD----------------------------------- MUL_3507|M.ulcerans_Agy99 AGMMGDGGAGGDGGDGS--------------------------------- Mflv_5091|M.gilvum_PYR-GCK TGTTGATGAAGEDGDAG--------------------------------- TH_3810|M.thermoresistible__bu EGIMPSSRAAS--------------------------------------- MAB_4284c|M.abscessus_ATCC_199 STAVGGGAHTSAINDALG-------------------------------- MAV_4827|M.avium_104 GGHLPFPGAGSTPGGSGG-------------------------------- MLBr_01556|M.leprae_Br4923 AIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIY Mvan_3867|M.vanbaalenii_PYR-1 ---------------------------RAAPVGKAAKAR-RAAAVAEATA MSMEG_3202|M.smegmatis_MC2_155 ---------------------------RSTPTRSADKAGSRTSSSSESNS Mb1121|M.bovis_AF2122/97 --GVLYGNGGAGGQGSSGGIGGPGATGGAGGKGGDGGDAQLIGDGGNGGN Rv1091|M.tuberculosis_H37Rv --GVLYGNGGAGGQGSSGGIGGPGATGGAGGKGGDGGDAQLIGDGGNGGN MMAR_2596|M.marinum_M --------------------------------GGDGGDAALVG---NGGN MUL_3507|M.ulcerans_Agy99 ---------------------------AAGGLGGDGGNADWLG----NGG Mflv_5091|M.gilvum_PYR-GCK ----------SGGSGINGGAGGAGGAGGEGGEGGDGGKGGAGAEGGAGGG TH_3810|M.thermoresistible__bu -----------------------------------------------ARA MAB_4284c|M.abscessus_ATCC_199 ---------------------GSGSVGGSTAVGGGAHTSAINESMNSSIN MAV_4827|M.avium_104 ---------------------------GHLPTPGAGTPGGGLGGFGGGHA MLBr_01556|M.leprae_Br4923 EENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDN Mvan_3867|M.vanbaalenii_PYR-1 PAPDGVVSLGPAYAQSRSATNALCCNEFSCAVTNSSEW----------- MSMEG_3202|M.smegmatis_MC2_155 ESNSESSSKTSSKAGGTKSSDTKSGGGAAGTGSDSKDSE---------- Mb1121|M.bovis_AF2122/97 GGAGGT--GGTPGPGGPGGSGGLGGLLFGQTGTAGVSP----------- Rv1091|M.tuberculosis_H37Rv GGAGGT--GGTPGPGGPGGSGGLGGLLFGQTGTAGVSP----------- MMAR_2596|M.marinum_M GGAGGS--GVTDGAGGRGGAGGG---LYGTPGMSG-------------- MUL_3507|M.ulcerans_Agy99 GGTGGF--GLPPATGGFGGRGGR---LFGSPGAQGRRALMCLSAACRC- Mflv_5091|M.gilvum_PYR-GCK GGAGGSGAGGAGGAGGSGGSGGSGG-SGGSGGAAGDSDD---------- TH_3810|M.thermoresistible__bu GAACAS--STSRSRRSFCCSRA--------------------------- MAB_4284c|M.abscessus_ATCC_199 ASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH MAV_4827|M.avium_104 PAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-------- MLBr_01556|M.leprae_Br4923 LTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA-