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MRRHGWAGNIPVDDDEAVSRIVAAARASIDARGTVSVSEVATELGITRQTVYRYFPTLDALLTGTALSAV GGFLDRLAQDLASITDPAEAVVEGIAYTLEQLPHDRYLGLVMQPGKASAFAAGVTSDVAISFGRSILERL NVDWAGAGFSGQSLDELVEFMLRTLQSFILDPGGPDRHRGELRAFLHRWVAPAVELHHRSGFPEQA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4911 | - | - | 100% (206) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5152 | - | 1e-56 | 53.81% (197) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0372 | - | 7e-42 | 41.03% (195) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1606 | - | 3e-54 | 52.82% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 9e-07 | 24.59% (183) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4765 | - | 1e-46 | 48.97% (194) | putative regulatory protein TetR |
| M. marinum M | MMAR_0226 | - | 2e-40 | 43.59% (195) | hypothetical protein MMAR_0226 |
| M. avium 104 | MAV_1115 | - | 1e-78 | 73.10% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5854 | - | 1e-59 | 55.61% (196) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1262 | - | 1e-57 | 54.36% (195) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4888 | - | 4e-35 | 41.85% (184) | hypothetical protein MUL_4888 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4911|M.vanbaalenii_PYR-1 ------MRRHGWAGNIPVDDDEAVSRIVAAARASIDARGT--VSVSEVAT
MAV_1115|M.avium_104 ------MRRHGWSGDIPADDEEAVARILTATRRAIDERGT--VSVSQVAS
MSMEG_5854|M.smegmatis_MC2_155 ------MRTHGWSGSAPATDEEAIARILAAAGKAIDERGAD-FSIADVAR
TH_1262|M.thermoresistible__bu ------MRTHGWGGSAPASDEEAIARILEAAKRTIEERGAE-FSIADVAR
Mflv_1606|M.gilvum_PYR-GCK MAYSAFVRTHGWSGAKPASDDEAVARILEAAGKAIEERGAD-FSISDVAR
MMAR_0226|M.marinum_M -----MARRRGWNGAPPASDEEASRRIVDTAVRLIAETGSD-VSLAQVAA
MUL_4888|M.ulcerans_Agy99 -----MVSRPKRRGVSRIG------RGVRRHRRGIAETGSD-VSLAQVAA
MAB_4765|M.abscessus_ATCC_1997 -----MARRRGWDGQPPSSDEEAAERIVAAAVKLIGETGSA-VSLADVAA
Rv1255c|M.tuberculosis_H37Rv ------MAGTDWLS--ARRTELAADRILDAAERLFTQRDPASIGMNEIAK
. * : : .. ..: ::*
Mvan_4911|M.vanbaalenii_PYR-1 ELGITRQTVYRYFPTLDALLTGTALSAVGGFLDRLAQDLASITDPAEAVV
MAV_1115|M.avium_104 TLGVTRQTIYRYFPTHEALLGATALSAVEGFLDRLAAHLGSITDPTEAVV
MSMEG_5854|M.smegmatis_MC2_155 TLGVTRQTVYRYFPSTDALLVAAAVHAASGFLDRLAAHLSGITDPVEAVT
TH_1262|M.thermoresistible__bu AVGVTRQTVYRYFPSTDALLVAAAMHAAGDFLDRLAVHLQGITDPVEAVA
Mflv_1606|M.gilvum_PYR-GCK TVGVTRQTVYRYFSSTEALLVAAAVHAVDGFLDRLAAHLVGVTDPPEAVT
MMAR_0226|M.marinum_M SLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLTEAVRGMRDPAEAMA
MUL_4888|M.ulcerans_Agy99 SLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLTEAVRGMRDPAEAMA
MAB_4765|M.abscessus_ATCC_1997 ELGVIRQTVYRYFPTADALMHAASLASVDGFLDRLTHVVRGITDPAEALT
Rv1255c|M.tuberculosis_H37Rv AAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEPAERLL
* * *:***: : :** . . : .: : .: :* * :
Mvan_4911|M.vanbaalenii_PYR-1 EGIAYTLEQLPHDRYLGLVMQPGKASAFAAGVT-SDVAISFGRSILERLN
MAV_1115|M.avium_104 EGIAYTFEQLAHDRYLSLVFQPGKASAFTAGVT-SDIAISFGRSILQRFE
MSMEG_5854|M.smegmatis_MC2_155 EAIATALEWVPQDKHLGLLISPGRADAHTESVT-SDVAVDFARAMLRKFD
TH_1262|M.thermoresistible__bu EAIATTLEWLPEDTHIGLLVAPGRPTAHTESVT-SDVAIDFANRMLRRFD
Mflv_1606|M.gilvum_PYR-GCK EAVATALEWLPREKYIGLIMAPG-GSTHVQSVT-SDIALRFARDMVGRLD
MMAR_0226|M.marinum_M EAVMFTLRDVVRTPHLGILIAQPYAHTHPENLT-SEEAQVFGVRMLERFD
MUL_4888|M.ulcerans_Agy99 EAVMFTLRDVVRTPHLGILIAQPYAHTHPENLT-SEEAQVFGVRMLERFD
MAB_4765|M.abscessus_ATCC_1997 EGVLYTLEEVTRTPHLGIMMSEPYAHSHTSDMT-SDEAQAFGLRMLDRFD
Rv1255c|M.tuberculosis_H37Rv VSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAALAAAFLN---
.: ::. : :. . *: :. ::
Mvan_4911|M.vanbaalenii_PYR-1 VDWAGAGFSGQSLD-ELVEFMLRTLQSFILDPGG-PDRHRGELRAFLHRW
MAV_1115|M.avium_104 VDWGAAGFADAGLD-ELVEVMLRTLQSLIVDPGR-PPRTGAELRRFLQDW
MSMEG_5854|M.smegmatis_MC2_155 VDWAGLGFGDDDLD-ELAEHLLRIIQSFIIDPGR-PPRTGATLRSYLRRW
TH_1262|M.thermoresistible__bu VDWAAVGYSDADLD-ELAEHLLRVIQSFVIDPGR-PPRDGQSLRAYLRRW
Mflv_1606|M.gilvum_PYR-GCK VDWTAAGFDEAELD-QLSEHLLRIIQSFVLDPGR-PPRRGDELRSYLRRW
MMAR_0226|M.marinum_M VDWAEYGFADESARHDLVEFLLRVLLSFFVAPNV-PSRSDDELKSFIKRW
MUL_4888|M.ulcerans_Agy99 VDWAEYGFADESARHDLVEFLLRVLLSFFVAPNV-PSRSDDELKSFIRRW
MAB_4765|M.abscessus_ATCC_1997 VDWVQYGY-DDAAKRELVEFALRIMLSFFVSPNE-ATRSRDELRGFLKRW
Rv1255c|M.tuberculosis_H37Rv ----SLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAEFVVPI
* . :* : *:.: *. : ::
Mvan_4911|M.vanbaalenii_PYR-1 VAPAVELHHRSGFPEQA
MAV_1115|M.avium_104 VAPAVRAHAISR-----
MSMEG_5854|M.smegmatis_MC2_155 VGAAVKPAQASVQSPRV
TH_1262|M.thermoresistible__bu VGAAVTGAR--------
Mflv_1606|M.gilvum_PYR-GCK VGNALLRR---------
MMAR_0226|M.marinum_M VGGAILAQKR-------
MUL_4888|M.ulcerans_Agy99 VGGAIVAQKR-------
MAB_4765|M.abscessus_ATCC_1997 LGGAVLAQGR-------
Rv1255c|M.tuberculosis_H37Rv VTPASAAARKAGHPGPE
: *