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ARRRGWDGRPPANDEEASARIVEAAVALISETGSDVSIADVAASLGVIRQTVYRYFPTADALMRAAAIAS VDGFLDRLTAHVRGITDPAEAMTDGVLYTLEEVSRTPHLGIVLSEPYLHANSGSLASDEAQDFGMRMLKR FDVDWAAYGYDEAAQRELVEFTLRIMLSFFVAPNEATRSREELRRFIRRWLGGALLAQPRATAAPSSST*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2106 | - | - | 100% (210) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5854 | - | 4e-51 | 49.02% (204) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5040 | - | 3e-09 | 28.12% (192) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 3e-05 | 32.39% (71) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3011 | - | 5e-77 | 70.73% (205) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 3e-05 | 26.42% (106) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4765 | - | 9e-89 | 77.61% (201) | putative regulatory protein TetR |
| M. marinum M | MMAR_0226 | - | 6e-80 | 70.79% (202) | hypothetical protein MMAR_0226 |
| M. avium 104 | MAV_2960 | - | 2e-49 | 47.42% (194) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1262 | - | 8e-51 | 50.00% (194) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4888 | - | 6e-67 | 69.94% (173) | hypothetical protein MUL_4888 |
| M. vanbaalenii PYR-1 | Mvan_3496 | - | 3e-71 | 68.53% (197) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2106|M.smegmatis_MC2_155 ------------------MAR-RRGWDGRPPANDEEASARIVEAAVALIS
MAB_4765|M.abscessus_ATCC_1997 ------------------MAR-RRGWDGQPPSSDEEAAERIVAAAVKLIG
MMAR_0226|M.marinum_M ------------------MAR-RRGWNGAPPASDEEASRRIVDTAVRLIA
MUL_4888|M.ulcerans_Agy99 ------------------MVS-RPKRRGVSRIG------RGVRRHRRGIA
Mflv_3011|M.gilvum_PYR-GCK ------------------MARKRRGWGGNPPETDEEATRRIVAAAVDLIA
Mvan_3496|M.vanbaalenii_PYR-1 MVTASPVRRQRLCYRRATMARKRRGWGGDPPATDSEAAQRIVVAAVDLIA
MAV_2960|M.avium_104 ------------------MRS--HGWAGNTPASDAEAIERILDAADRIIA
TH_1262|M.thermoresistible__bu ------------------MRT--HGWGGSAPASDEEAIARILEAAKRTIE
Rv1255c|M.tuberculosis_H37Rv ------------------MAG--TDWLS--ARRTELAADRILDAAERLFT
Mb0068c|M.bovis_AF2122/97 ------------------MAP----TDRRVRADAARNRARVLEVAYQTFA
* * : :
MSMEG_2106|M.smegmatis_MC2_155 ETG-SDVSIADVAASLGVIRQTVYRYFPTADALMRAAAIASVDGFLDRLT
MAB_4765|M.abscessus_ATCC_1997 ETG-SAVSLADVAAELGVIRQTVYRYFPTADALMHAASLASVDGFLDRLT
MMAR_0226|M.marinum_M ETG-SDVSLAQVAASLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLT
MUL_4888|M.ulcerans_Agy99 ETG-SDVSLAQVAASLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLT
Mflv_3011|M.gilvum_PYR-GCK ETG-SAITIADVAESLGVIRQTVYRYFPTAQDLMREAAIASVDGFLDQLE
Mvan_3496|M.vanbaalenii_PYR-1 RTG-AAITIADVAESLEVTRQTVYRYFSTADELMRAAAIASVDGFLDQLA
MAV_2960|M.avium_104 ERG-SALRIADVARALGVTRQTVYRYFPGTQALLVASAMRSADGFLDRMA
TH_1262|M.thermoresistible__bu ERG-AEFSIADVARAVGVTRQTVYRYFPSTDALLVAAAMHAAGDFLDRLA
Rv1255c|M.tuberculosis_H37Rv QRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIM
Mb0068c|M.bovis_AF2122/97 ADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGH
. . : ::* *:**:: : * : .
MSMEG_2106|M.smegmatis_MC2_155 AHVRGITDPAEAMTDGVLYTLEEVSRTPHLGIVLSEPYL-HANSGSLASD
MAB_4765|M.abscessus_ATCC_1997 HVVRGITDPAEALTEGVLYTLEEVTRTPHLGIMMSEPYA-HSHTSDMTSD
MMAR_0226|M.marinum_M EAVRGMRDPAEAMAEAVMFTLRDVVRTPHLGILIAQPYA-HTHPENLTSE
MUL_4888|M.ulcerans_Agy99 EAVRGMRDPAEAMAEAVMFTLRDVVRTPHLGILIAQPYA-HTHPENLTSE
Mflv_3011|M.gilvum_PYR-GCK ARVRGITDPADAMTEGFLFTLDAVVAIPHLGILLSSPSS-AATPGEVASA
Mvan_3496|M.vanbaalenii_PYR-1 AHVRGIHDPADAMTEGVMFTLDAVAAIPHLAILLSAPSE-AARPSEVTSD
MAV_2960|M.avium_104 AHLDGVTDPVVAITEGMAFAVEELASDHQVEFVLNQRHR-GGQKVSIISD
TH_1262|M.thermoresistible__bu VHLQGITDPVEAVAEAIATTLEWLPEDTHIGLLVAPGRP-TAHTESVTSD
Rv1255c|M.tuberculosis_H37Rv VKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSE
Mb0068c|M.bovis_AF2122/97 ALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVGIEISSAAPEAEA
: . . .: : . .
MSMEG_2106|M.smegmatis_MC2_155 EAQDFGMRMLKRFDVDWAAYGY-DEAAQRELVEFTLRIMLSFFVAPNEAT
MAB_4765|M.abscessus_ATCC_1997 EAQAFGLRMLDRFDVDWVQYGY-DDAAKRELVEFALRIMLSFFVSPNEAT
MMAR_0226|M.marinum_M EAQVFGVRMLERFDVDWAEYGFADESARHDLVEFLLRVLLSFFVAPNVPS
MUL_4888|M.ulcerans_Agy99 EAQVFGVRMLERFDVDWAEYGFADESARHDLVEFLLRVLLSFFVAPNVPS
Mflv_3011|M.gilvum_PYR-GCK LAQDVGMRMITRFDVDWQRYGY-DDAALRDLVEFTLRTMLSFFVAPNDPS
Mvan_3496|M.vanbaalenii_PYR-1 LAQDFGMRMITRFDVDWQRYGY-DDAALRDLVEFTLRTMLSFFVAPN--V
MAV_2960|M.avium_104 TALAFGRSMLHRYDIDWESYGF-DEAGLEELNEFSLRVLHSFLTDPGRPP
TH_1262|M.thermoresistible__bu VAIDFANRMLRRFDVDWAAVGY-SDADLDELAEHLLRVIQSFVIDPGRPP
Rv1255c|M.tuberculosis_H37Rv VIAALAAAFLN-------SLGPDDPTTVERRARWVVRMLTSLLMFPG---
Mb0068c|M.bovis_AF2122/97 DFLDLLTDLLR-----------AAQRAGTVRPDVDVLEVKTLLVGCQAMQ
. :: : : ::.
MSMEG_2106|M.smegmatis_MC2_155 RSREELRRFIRRWLGGALLAQPRATAAPSSST---------------
MAB_4765|M.abscessus_ATCC_1997 RSRDELRGFLKRWLGGAVLAQGR------------------------
MMAR_0226|M.marinum_M RSDDELKSFIKRWVGGAILAQKR------------------------
MUL_4888|M.ulcerans_Agy99 RSDDELKSFIRRWVGGAIVAQKR------------------------
Mflv_3011|M.gilvum_PYR-GCK RSREELRRFLRRWLGSAILAQASPSRISPSISSTG------------
Mvan_3496|M.vanbaalenii_PYR-1 RPPEELRRFLTRWLGSAILAQSVKA----------------------
MAV_2960|M.avium_104 RTGADLRRYLTRWIGPAIAYPQLLRAMDALGAAEPQQRPRRRASKAS
TH_1262|M.thermoresistible__bu RDGQSLRAYLRRWVGAAVTGAR-------------------------
Rv1255c|M.tuberculosis_H37Rv RDEADERAMIAEFVVPIVTPASAAARKAGHPGPE-------------
Mb0068c|M.bovis_AF2122/97 SYNAELAAKVTDVALDGLRANRK------------------------
. : :