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FTSHRTASTLRGMSDPQLQQMTATLDELDGRERALRAEVDALRGRMVEWTQAEYLKAQRYWDDYRRAQGV AQAVAPAPVVMPPARMPVPARAPHPAPPQLEPWWMREGFASKAMALAGAVVTLAGVVMLLVLAAKSGYFG PVPRMVSGAALAGGLVALGIRVYSRPGGRVGGIATAATGFAAAFFDVLALTVIYDRIPVVAGLVLGLGIA GVGLVLARHWNSQPFASGVVAAITVLAPFLTDGFTVELAAFALILLIASLTAQVGRNWPVLHAFRTVGVS LTLLTAIHVSYTASLALLAMSVMALLVTLVGSLWLLTGEHDDITSSVMIAVASSPVLYGALFFPVWPLGV LVPVGVAVVMGAVLLLVGALPVHARITVAAVAGVALLQASVDGARDALLAVVLLAIALSCCAIGYQLRDR VALVLGQVFGGLGAAVYLAYVRPELLTDSASAVLYAGPLLVIASVLMAATVGMVLATMARVGWASPQSAP TRAVLAGVSMLYSGTAAVVLSGTALLGNNDGFLLGHGLATVSWMAVSVALLLAGLRRYRGRSWVTRTGFV LAAMAVAKLFLFDLATLDGVARIGAFIVTGLLLLGGGTLYAREYATRSEEPSAERPVT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4509c | - | - | 100% (619) | hypothetical protein MAB_4509c |
| M. abscessus ATCC 19977 | MAB_0636c | - | 2e-05 | 26.80% (291) | putative monovalent cation/H+ antiporter subunit A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3714 | - | 5e-05 | 30.83% (133) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_3578 | - | 2e-75 | 36.92% (577) | hypothetical protein Mflv_3578 |
| M. tuberculosis H37Rv | Rv3689 | - | 5e-05 | 30.83% (133) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3960 | - | 9e-79 | 33.97% (624) | hypothetical protein MMAR_3960 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3241 | - | 4e-76 | 37.05% (610) | hypothetical protein MSMEG_3241 |
| M. thermoresistible (build 8) | TH_4594 | - | 2e-41 | 33.81% (420) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2837 | - | 1e-77 | 38.29% (551) | hypothetical protein Mvan_2837 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3578|M.gilvum_PYR-GCK MADMTEPHSAVIARLSADFAAISHQLTRVSGDLAALDRILTD-----RAP
Mvan_2837|M.vanbaalenii_PYR-1 ---MTEPHTAVITRLSADFAAISRQLARVSTDLVELDRILAD-----RPQ
TH_4594|M.thermoresistible__bu --------------------------------------------------
MMAR_3960|M.marinum_M ---MTESQHAVISRLSAEFDSLARQMARVSGELSQLDRLISDSVGAPQPA
MSMEG_3241|M.smegmatis_MC2_155 ---MTEPQRAVIARVTADLTAVSAYLNRMAGDLATLDRLVAQQSAAPRPE
MAB_4509c|M.abscessus_ATCC_199 ----MFTSHRTASTLRGMSDPQLQQMTATLDELDGRERALRAEVDALRGR
Mb3714|M.bovis_AF2122/97 --------------------------------------------------
Rv3689|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3578|M.gilvum_PYR-GCK AAAAPR-------------------PAPQPAAYWPQYP-PQPAPFRPWPQ
Mvan_2837|M.vanbaalenii_PYR-1 SAPAPWPQPVSVP-------SPVPVPSPVPVAQPVPVPSPAPVPQPVAPY
TH_4594|M.thermoresistible__bu --------------------------------------------------
MMAR_3960|M.marinum_M AAAPPQPQPQPVAPYWYPYWQQWAPVAPAPAAAPPRQYAPPPTARPAPQG
MSMEG_3241|M.smegmatis_MC2_155 AVAPQWS--------------------PQAPQQPPRQWTPQPVAPVAPVA
MAB_4509c|M.abscessus_ATCC_199 MVEWTQAEYLKAQR------------YWDDYRRAQGVAQAVAPAPVVMPP
Mb3714|M.bovis_AF2122/97 ----------------------------MHKRYAPQRPKPDTETYIEKCT
Rv3689|M.tuberculosis_H37Rv ----------------------------MHKRYAPQRPKPDTETYIEKCT
Mflv_3578|M.gilvum_PYR-GCK APAPAPTQALTPAP---RKERSE-GWIGKLLAVAGVAVTLIGVVLLLVLA
Mvan_2837|M.vanbaalenii_PYR-1 RPAYPAYPAYPPASARVRKERSD-GWIGKLLAVAGVAVTLIGVVLLLVLA
TH_4594|M.thermoresistible__bu --------------------------------------------------
MMAR_3960|M.marinum_M PPAPAPAAAPPVSAPRRPAESTESGWIGKLLAVAGVAVTLTGVALLLVLA
MSMEG_3241|M.smegmatis_MC2_155 VPARQPDTPP--------KPRSE-GWIGKVLAMAGVAVTLVGVVSLLVLA
MAB_4509c|M.abscessus_ATCC_199 ARMPVPARAPHPAPPQLEPWWMREGFASKAMALAGAVVTLAGVVMLLVLA
Mb3714|M.bovis_AF2122/97 DRRQDG-----------------------------------------GHD
Rv3689|M.tuberculosis_H37Rv DRRQDG-----------------------------------------GHD
Mflv_3578|M.gilvum_PYR-GCK AQAGILRPEFRVSAGGALAAALVGAGWWLNTRPGGRVGAIALVATGVAAA
Mvan_2837|M.vanbaalenii_PYR-1 AQAGILRPEFRVAAGAVLAGALVAAGWWLNGRPGGRVGAIALVATGVAAA
TH_4594|M.thermoresistible__bu --------------------------------------------------
MMAR_3960|M.marinum_M AQAGLLRPEIRVAGGTALSLALVGVAVRLRGRPGGRIGAIALAATGIATA
MSMEG_3241|M.smegmatis_MC2_155 AQAGILRPEVRVAAGAALAVALVAVAMWLDRRPGGRVGAVALAATGVAAA
MAB_4509c|M.abscessus_ATCC_199 AKSGYFGPVPRMVSGAALAGGLVALGIRVYSRPGGRVGGIATAATGFAAA
Mb3714|M.bovis_AF2122/97 ERRQLLRPVSMLPPGYPVEPPPVAPGYAPAGYPPYPATPPGYGPPGYGAP
Rv3689|M.tuberculosis_H37Rv ERRQLLRPVSMLPPGYPVEPPPVAPGYAPAGYPPYPATPPGYGPPGYGAP
Mflv_3578|M.gilvum_PYR-GCK YMDVIAVTTIYDWVPAPAGLVLAAVIAGAGLTLARRWDSEHLGLLVLVPL
Mvan_2837|M.vanbaalenii_PYR-1 YMDVIAVTTIYEWTSAPAGLVFASLIAGGGLTLARRWDSEHLGLLVLVPL
TH_4594|M.thermoresistible__bu -------------------------------MLARRWDSEHLGLLVLVPL
MMAR_3960|M.marinum_M YLDVIAATTIYQWVPAPAGLVLAALVGGAGLALARRWDSEHLGLLVLVPL
MSMEG_3241|M.smegmatis_MC2_155 YMDVIAVTAIYEWVPAPVGLALAGVVGACGLMLARWWGSEQLGLLVFVPL
MAB_4509c|M.abscessus_ATCC_199 FFDVLALTVIYDRIPVVAGLVLGLGIAGVGLVLARHWNSQPFASGVVAAI
Mb3714|M.bovis_AF2122/97 ---------PSYGPPPGYGPPLGYPAAPPGCGPPPGYG----------PP
Rv3689|M.tuberculosis_H37Rv ---------PSYGPPPGYGPPLGYPAAPPGCGPPPGYG----------PP
. :. .
Mflv_3578|M.gilvum_PYR-GCK IVLAPIVTDGVSLLLVGFMLALAAVSLPVQLGKDWIWLHAARIAAAVLPL
Mvan_2837|M.vanbaalenii_PYR-1 IGLAPIVTDGISLLLVGFMLALAAVSLPVQLGKDWIWLHAARIAAAALPV
TH_4594|M.thermoresistible__bu VLLAPVITDGITVVLIGFMLALGAASLPVQLGRDWIWLHAARTASVTLPI
MMAR_3960|M.marinum_M IGLAPVLTRGADLLLVSFMLALSAAALPVQLGKDWVWLHAARVAAPTVPL
MSMEG_3241|M.smegmatis_MC2_155 IALAPVITDGVTLLLIGFMLALSAASLPVQFGRDWFWLHAARTAAVTIPL
MAB_4509c|M.abscessus_ATCC_199 TVLAPFLTDGFTVELAAFALILLIASLTAQVGRNWPVLHAFRTVGVSLTL
Mb3714|M.bovis_AF2122/97 LGYGPPLAPG---AVKPGIIPLRPLTLSDIFNGAVGYIRANPKATLGLTA
Rv3689|M.tuberculosis_H37Rv LGYGPPVAPG---AVKPGIIPLRPLTLSDIFNGAVGYIRANPKATLGLTA
.* :: * : : * :*. .. ::* . :.
Mflv_3578|M.gilvum_PYR-GCK LVALAARHID-SREDLWLAGACGIAAVIALTAALILLPGTGNRVVMALLT
Mvan_2837|M.vanbaalenii_PYR-1 LTALLARHFESARQDLWLAGASGIAAAVALVAALILLPGTKNRAAMALLT
TH_4594|M.thermoresistible__bu LGALLGASFAQDRVPALTA-ACGIAAVLALAAALLLAPSTRNHTALGLLT
MMAR_3960|M.marinum_M LIALVAAGKH--DNTWLLGAACGVAAILAIVSGLIVLPGGKNAAALAVLT
MSMEG_3241|M.smegmatis_MC2_155 LVALVSAAIG-GREDLRLALVCALAAVPALVGGVTVSRFSTRPVATTVVS
MAB_4509c|M.abscessus_ATCC_199 LTAIHVSYTA----SLALLAMSVMALLVTLVGSLWLLTGEHDDITSSVMI
Mb3714|M.bovis_AF2122/97 MVVVTLQIIS------------LVALFGPMTAFGDIVTGEPDELTG---A
Rv3689|M.tuberculosis_H37Rv MVVVTLQIIS------------LVALFGPMTAFGDIVTGEPDELTG---A
: .: :* .:.. : .
Mflv_3578|M.gilvum_PYR-GCK VAGIVPVLCVNLAVDRVVAALMAAALAAALLAVALLA--DRLPGV-DGVV
Mvan_2837|M.vanbaalenii_PYR-1 AAGVLPVLCVSLAVDRVVAALMAATLAAALLAIVLFG--ERLPGV-AGVV
TH_4594|M.thermoresistible__bu AAGTLPVLCVSWAERPAVSALMAAALSAALLAMAAGAGLIRVELVRTGPL
MMAR_3960|M.marinum_M VVGTLPVLAAAVAVDRVFAALLAGTLAAALLAIVLVG--SELPTI----F
MSMEG_3241|M.smegmatis_MC2_155 ALGTVPLLCVSATADRVPAVLLIAGLAAAALAVAAIG--DRLPGI-GAPV
MAB_4509c|M.abscessus_ATCC_199 AVASSPVLYGALFFPVWPLGVLVPVGVAVVMGAVLLL-----VGALPVHA
Mb3714|M.bovis_AF2122/97 VVGGWSASFGASLLVSWLAGVLLSGMLTVIVGRAVFG-------------
Rv3689|M.tuberculosis_H37Rv VVGGWSASFGASLLVSWLAGVLLSGMLTVIVGRAVFG-------------
. . . :: :. :. .
Mflv_3578|M.gilvum_PYR-GCK RRVFAVTSAIAALIAVTTAFDGRVGGPVLLAMAVVVAIAV--GRDVVGRW
Mvan_2837|M.vanbaalenii_PYR-1 RQVFSATSAVAALIAVTVAFDGMIAGPVLLAMAVVVALVG--RRDEVARW
TH_4594|M.thermoresistible__bu RRILSVWAAVAALIAVTVAFDAPVAAPVLLAMATVVAVAG--RHDRTARW
MMAR_3960|M.marinum_M TRVLAAWSAISALVAVTVAFDGHVEGPILLALAIVVAIAG--RHDRMALW
MSMEG_3241|M.smegmatis_MC2_155 RRVWAATSAAAALIAVLVAFDGTVAAPVLLAMSIAIAVGG--QRDPVGRC
MAB_4509c|M.abscessus_ATCC_199 RITVAAVAGVALLQASVDGARDALLAVVLLAIALSCCAIGYQLRDRVALV
Mb3714|M.bovis_AF2122/97 -----SPITVGEAWAKVRGRLLALFGLALLEAAGVVAVLG------LAVV
Rv3689|M.tuberculosis_H37Rv -----SPITVGEAWAKVRGRLLALFGLALLEAAGVVAVLG------LAVV
. * . : . ** : . .
Mflv_3578|M.gilvum_PYR-GCK VAIGFAVIGAAAHLSYAPLAVLLQPVEVSTATGISTLVSSLLLATAAVTI
Mvan_2837|M.vanbaalenii_PYR-1 AAIGFAVVGAGVHLSYSPPSMLLEATRISAAAGISTLVSAVLLAAAAVAV
TH_4594|M.thermoresistible__bu IALGFAVVGGLYYLGVAPPYRVLRPIAVAAPTAVAVLIASVLLICCVVAI
MMAR_3960|M.marinum_M AAAGFGIVGLGLYYSYAPLHALLTATVMPTSIAVSTLAASLLSIAFVVAM
MSMEG_3241|M.smegmatis_MC2_155 AAIGFALIGAMFYLDHAAPAMLVEATPLDGPTVASVVIGSVMLIGAAAAN
MAB_4509c|M.abscessus_ATCC_199 LGQVFGGLGAAVYLAYVRPELLTDSASAVLYAGPLLVIASVLMAATVGMV
Mb3714|M.bovis_AF2122/97 ILSGVAAAANEAAAALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPI
Rv3689|M.tuberculosis_H37Rv ILSGVAAAANEAAAALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPI
.. . : : ..::
Mflv_3578|M.gilvum_PYR-GCK VWMWDRT----ETALWVGAAV---VTVYAVTSCTVTAGMLVIGGDGGFYA
Mvan_2837|M.vanbaalenii_PYR-1 VWAWDHTGGATGLAIWIVPAA---VVVYAVTSFTVTAGMLIGGGDGGFYA
TH_4594|M.thermoresistible__bu VWTWRAHVPAAGPLPWLGAAT---VLLYAVTTFTVTAGVLAGGVGGGFFA
MMAR_3960|M.marinum_M SRACAGIGGQNRDIRRILAAVGGVLVIYAVTAFTVTAGVLIAGTEAGFLA
MSMEG_3241|M.smegmatis_MC2_155 GWTWSRTVSDTEVVRLVWVAVS-AVIGYAATALTVTVGVALGGAEVGFLA
MAB_4509c|M.abscessus_ATCC_199 LATMARVGWASPQSAPTRAVLAGVSMLYSGTAAVVLSGTALLGNNDGFLL
Mb3714|M.bovis_AF2122/97 VEAITRSFALVRHGFWR-------VLGIRLLTVLVVGVVGNAIAAPFMIV
Rv3689|M.tuberculosis_H37Rv VEAITRSFALVRHGFWR-------VLGIRLLTVLVVGVVGNAIAAPFMIV
: * :
Mflv_3578|M.gilvum_PYR-GCK GHMVATILWIAMAAVLFWYAARLP-REDRSVPLGGGLGLVAAAMAKLFLF
Mvan_2837|M.vanbaalenii_PYR-1 GHMAATICWIAMAAALFGYAARLP-REDRSMLIGGGLGLVAAAMAKLFLF
TH_4594|M.thermoresistible__bu GHMAATICWIGLAAALLWYAARRP-RADRAMPLGGGLALVAAAVAKLFLF
MMAR_3960|M.marinum_M GHMAATICWIAVAAALFVYALRVADRERRTAPIGAGLALTGAATAKLFLF
MSMEG_3241|M.smegmatis_MC2_155 GHMAATLSWIVAAALAFGYAARRP-GASRSVLIGGGLVLVAAATGKLFLF
MAB_4509c|M.abscessus_ATCC_199 GHGLATVSWMAVSVALLLAGLRRY--RGRSWVTRTGFVLAAMAVAKLFLF
Mb3714|M.bovis_AF2122/97 GEIVTAVTASDGSVTMRLVGATLS-------AIGVTIGQIVTAPFSAGVV
Rv3689|M.tuberculosis_H37Rv GEIVTAVTASDGSVTMRLVGATLS-------AIGVTIGQIVTAPFSAGVV
*. ::: :. . : * . :.
Mflv_3578|M.gilvum_PYR-GCK DLGTLDGIFRVVVFIVVGLTLLGIGAGYARLLERQDKQAATRTFDTT---
Mvan_2837|M.vanbaalenii_PYR-1 DLGTLDGIFRVAVFIVVGLILLGMGAGYARLLEKQDKKL-----------
TH_4594|M.thermoresistible__bu DLGTLDGIFRVVVFIVVGLVLLGTGGGYARWLTHAAGESHPAGESRGTGK
MMAR_3960|M.marinum_M DLATLDGIFRVAAFIVVGLVLLAMGTGYARSLAR----------------
MSMEG_3241|M.smegmatis_MC2_155 DLGTLDGMYRVVLFIVGGLVLLGMGAGYARFLAQQSDGRSDAQPGTDHEA
MAB_4509c|M.abscessus_ATCC_199 DLATLDGVARIGAFIVTGLLLLGGGTLYAREYATRSEEPSAERPVT----
Mb3714|M.bovis_AF2122/97 VLLYTDRRIRAEAFDLVLQTGLEAGPAGGPAPVESTDNLWLTRPF-----
Rv3689|M.tuberculosis_H37Rv VLLYTDRRIRAEAFDLVLQTGLEAGPAGGPAPVESTDNLWLTRPF-----
* * * * : * * .
Mflv_3578|M.gilvum_PYR-GCK --------
Mvan_2837|M.vanbaalenii_PYR-1 --------
TH_4594|M.thermoresistible__bu HQADNEPV
MMAR_3960|M.marinum_M --------
MSMEG_3241|M.smegmatis_MC2_155 HST-----
MAB_4509c|M.abscessus_ATCC_199 --------
Mb3714|M.bovis_AF2122/97 --------
Rv3689|M.tuberculosis_H37Rv --------