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M. thermoresistible (build 8) TH_4594 (-)

annotation: putative conserved hypothetical protein
coordinates: 2113960 - 2115222
length: 421

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4594--100% (421)putative conserved hypothetical protein
M. thermoresistible (build 8)TH_1908-2e-0727.91% (258) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. thermoresistible (build 8)TH_3409-2e-0627.27% (286) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0086-2e-0526.96% (293) oxidoreductase
M. gilvum PYR-GCKMflv_3578-1e-12460.31% (393) hypothetical protein Mflv_3578
M. tuberculosis H37RvRv0083-2e-0526.96% (293) oxidoreductase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4509c-1e-4133.81% (420) hypothetical protein MAB_4509c
M. marinum MMMAR_3960-1e-10454.98% (402) hypothetical protein MMAR_3960
M. avium 104MAV_4863-7e-0726.28% (331) hypothetical protein MAV_4863
M. smegmatis MC2 155MSMEG_3241-1e-10350.96% (418) hypothetical protein MSMEG_3241
M. ulcerans Agy99MUL_1895hycQ5e-0725.89% (394) hydrogenase HycQ
M. vanbaalenii PYR-1Mvan_2837-1e-12861.77% (395) hypothetical protein Mvan_2837

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3578|M.gilvum_PYR-GCK          MADMTEPHSAVIARLSADFAAISHQLTRVSGDLAALDRILTD-----RAP
Mvan_2837|M.vanbaalenii_PYR-1       ---MTEPHTAVITRLSADFAAISRQLARVSTDLVELDRILAD-----RPQ
TH_4594|M.thermoresistible__bu      --------------------------------------------------
MMAR_3960|M.marinum_M               ---MTESQHAVISRLSAEFDSLARQMARVSGELSQLDRLISDSVGAPQPA
MSMEG_3241|M.smegmatis_MC2_155      ---MTEPQRAVIARVTADLTAVSAYLNRMAGDLATLDRLVAQQSAAPRPE
MAB_4509c|M.abscessus_ATCC_199      ----MFTSHRTASTLRGMSDPQLQQMTATLDELDGRERALRAEVDALRGR
Mb0086|M.bovis_AF2122/97            -----MTAAPTAGGVVTSGVGVAGVGVGLLGMFGPVRVVHVGWLLPLSGV
Rv0083|M.tuberculosis_H37Rv         -----MTAAPTAGGVVTSGVGVAGVGVGLLGMFGPVRVVHVGWLLPLSGV
MUL_1895|M.ulcerans_Agy99           --------------------------------------------------
MAV_4863|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3578|M.gilvum_PYR-GCK          AAAAPR-------------------PAPQPAAYWPQYP-PQPAPFRPWPQ
Mvan_2837|M.vanbaalenii_PYR-1       SAPAPWPQPVSVP-------SPVPVPSPVPVAQPVPVPSPAPVPQPVAPY
TH_4594|M.thermoresistible__bu      --------------------------------------------------
MMAR_3960|M.marinum_M               AAAPPQPQPQPVAPYWYPYWQQWAPVAPAPAAAPPRQYAPPPTARPAPQG
MSMEG_3241|M.smegmatis_MC2_155      AVAPQWS--------------------PQAPQQPPRQWTPQPVAPVAPVA
MAB_4509c|M.abscessus_ATCC_199      MVEWTQAEYLKAQR------------YWDDYRRAQGVAQAVAPAPVVMPP
Mb0086|M.bovis_AF2122/97            HIELDRLGG-----------------FFMALTGAVAAPVGCYLIGYVRRE
Rv0083|M.tuberculosis_H37Rv         HIELDRLGG-----------------FFMALTGAVAAPVGCYLIGYVRRE
MUL_1895|M.ulcerans_Agy99           --------------------------------------------------
MAV_4863|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_3578|M.gilvum_PYR-GCK          APAPAPTQALTPAP---RKERSE-GWIGKLLAVAGVAVTLIGVVLLLVLA
Mvan_2837|M.vanbaalenii_PYR-1       RPAYPAYPAYPPASARVRKERSD-GWIGKLLAVAGVAVTLIGVVLLLVLA
TH_4594|M.thermoresistible__bu      --------------------------------------------------
MMAR_3960|M.marinum_M               PPAPAPAAAPPVSAPRRPAESTESGWIGKLLAVAGVAVTLTGVALLLVLA
MSMEG_3241|M.smegmatis_MC2_155      VPARQPDTPP--------KPRSE-GWIGKVLAMAGVAVTLVGVVSLLVLA
MAB_4509c|M.abscessus_ATCC_199      ARMPVPARAPHPAPPQLEPWWMREGFASKAMALAGAVVTLAGVVMLLVLA
Mb0086|M.bovis_AF2122/97            HLGRVPMAVVPLFVAAMLLVPAAGSVTTFLLAWELMAIASLILVLSEHAR
Rv0083|M.tuberculosis_H37Rv         HLGRVPMAVVPLFVAAMLLVPAAGSVTTFLLAWELMAIASLILVLSEHAR
MUL_1895|M.ulcerans_Agy99           -----------------------------MTALILVPIVAPLVAAAFALA
MAV_4863|M.avium_104                ------------------------MTSGTVMPIVRVAILADSRLTEMALP
                                                                                      

Mflv_3578|M.gilvum_PYR-GCK          AQAGILRPEFRVSAGGALAAALVGAGWWLNTRPGGRVGAIALVATGVAAA
Mvan_2837|M.vanbaalenii_PYR-1       AQAGILRPEFRVAAGAVLAGALVAAGWWLNGRPGGRVGAIALVATGVAAA
TH_4594|M.thermoresistible__bu      --------------------------------------------------
MMAR_3960|M.marinum_M               AQAGLLRPEIRVAGGTALSLALVGVAVRLRGRPGGRIGAIALAATGIATA
MSMEG_3241|M.smegmatis_MC2_155      AQAGILRPEVRVAAGAALAVALVAVAMWLDRRPGGRVGAVALAATGVAAA
MAB_4509c|M.abscessus_ATCC_199      AKSGYFGPVPRMVSGAALAGGLVALGIRVYSRPGGRVGGIATAATGFAAA
Mb0086|M.bovis_AF2122/97            PQVRSAGLWYAVMTQLGFIAILVGLVVLAAAGGSDRFAGLGAVCDGVRVA
Rv0083|M.tuberculosis_H37Rv         PQVRSAGLWYAVMTQLGFIAILVGLVVLAAAGGSDRFAGLGAVCDGVRAA
MUL_1895|M.ulcerans_Agy99           GGWRRATAVLTVLSAVAVLGSGIALGLQATPQPHLVLGGLLRVDA-----
MAV_4863|M.avium_104                AELPLREILPAVQR------LVVPAAANGDSEDGAPSRGAAEVGGAVQLS
                                                                                      

Mflv_3578|M.gilvum_PYR-GCK          YMDVIAVTTIYDWVPAPAGLVLAAVIAGAGLTLARRWDSEHLGLLVLVPL
Mvan_2837|M.vanbaalenii_PYR-1       YMDVIAVTTIYEWTSAPAGLVFASLIAGGGLTLARRWDSEHLGLLVLVPL
TH_4594|M.thermoresistible__bu      -------------------------------MLARRWDSEHLGLLVLVPL
MMAR_3960|M.marinum_M               YLDVIAATTIYQWVPAPAGLVLAALVGGAGLALARRWDSEHLGLLVLVPL
MSMEG_3241|M.smegmatis_MC2_155      YMDVIAVTAIYEWVPAPVGLALAGVVGACGLMLARWWGSEQLGLLVFVPL
MAB_4509c|M.abscessus_ATCC_199      FFDVLALTVIYDRIPVVAGLVLGLGIAGVGLVLARHWNSQPFASGVVAAI
Mb0086|M.bovis_AF2122/97            VFMLTLVGFGSKAGLVPLHAWLPRAHPEAPSPVSALMSAAMVNLGIYGIV
Rv0083|M.tuberculosis_H37Rv         VFMLTLVGFGSKAGLVPLHAWLPRAHPEAPSPVSALMSAAMVNLGIYGIV
MUL_1895|M.ulcerans_Agy99           -LSVIMLIVIGAVGTLATWASIGYIDAELEHGHTDRRDARLYGALMPAFL
MAV_4863|M.avium_104                LAPIGGAPFSLDASLDTVGVVDGDLLALQPVPAGPAAPGIVEDIADAAMI
                                                                          .          :

Mflv_3578|M.gilvum_PYR-GCK          IVLAPIVTDG-----VSLLLVG---FMLALAAVSLPVQLGKDWIWLHAAR
Mvan_2837|M.vanbaalenii_PYR-1       IGLAPIVTDG-----ISLLLVG---FMLALAAVSLPVQLGKDWIWLHAAR
TH_4594|M.thermoresistible__bu      VLLAPVITDG-----ITVVLIG---FMLALGAASLPVQLGRDWIWLHAAR
MMAR_3960|M.marinum_M               IGLAPVLTRG-----ADLLLVS---FMLALSAAALPVQLGKDWVWLHAAR
MSMEG_3241|M.smegmatis_MC2_155      IALAPVITDG-----VTLLLIG---FMLALSAASLPVQFGRDWFWLHAAR
MAB_4509c|M.abscessus_ATCC_199      TVLAPFLTDG-----FTVELAA---FALILLIASLTAQVGRNWPVLHAFR
Mb0086|M.bovis_AF2122/97            RFDLQLLGPGPRWWGLALLAVGGTSALYGVLQASVAADLKRLLAYSTTEN
Rv0083|M.tuberculosis_H37Rv         RFDLQLLGPGPRWWGLALLAVGGTSALYGVLQASVAADLKRLLAYSTTEN
MUL_1895|M.ulcerans_Agy99           AAMAIAVSANNIGLIWVAVEATTVVTAFLVGHRRTRTALEATWKYVVICS
MAV_4863|M.avium_104                FSTSRLRPWG-------TTHIQRFALATVIAVALLATGLSVSYRVATGAL
                                             .                   :      . .           

Mflv_3578|M.gilvum_PYR-GCK          IAAAVLPLLVAL-AARHID-SREDLWLAGACGIAAVIALTAALILLPGTG
Mvan_2837|M.vanbaalenii_PYR-1       IAAAALPVLTAL-LARHFESARQDLWLAGASGIAAAVALVAALILLPGTK
TH_4594|M.thermoresistible__bu      TASVTLPILGAL-LGASFAQDRVPALTA-ACGIAAVLALAAALLLAPSTR
MMAR_3960|M.marinum_M               VAAPTVPLLIAL-VAAGKH--DNTWLLGAACGVAAILAIVSGLIVLPGGK
MSMEG_3241|M.smegmatis_MC2_155      TAAVTIPLLVAL-VSAAIG-GREDLRLALVCALAAVPALVGGVTVSRFST
MAB_4509c|M.abscessus_ATCC_199      TVGVSLTLLTAI-HVSYTA----SLALLAMSVMALLVTLVGSLWLLTGEH
Mb0086|M.bovis_AF2122/97            MGLITLALGAAT-LFADTGAYGPASIAAAAAMLHMIAHAAFKSLAFMAAG
Rv0083|M.tuberculosis_H37Rv         MGLITLALGAAT-LFADTGAYGPASIAAAAAMLHMIAHAAFKSLAFMAAG
MUL_1895|M.ulcerans_Agy99           VGIAVAFLGTVL-LYFAAQHAGADGANALNLDVLTACAAHLNPAVTRLAG
MAV_4863|M.avium_104                AGLVAVSAVAALTAIVGLLATARSPRNGMALSIAALVPIGAALALAVPGR
                                              .                     :                 

Mflv_3578|M.gilvum_PYR-GCK          NRVVMALLTVAGIVPVLCVNLAVDRVVAALMAAALAAALLAVALLA--DR
Mvan_2837|M.vanbaalenii_PYR-1       NRAAMALLTAAGVLPVLCVSLAVDRVVAALMAATLAAALLAIVLFG--ER
TH_4594|M.thermoresistible__bu      NHTALGLLTAAGTLPVLCVSWAERPAVSALMAAALSAALLAMAAGAGLIR
MMAR_3960|M.marinum_M               NAAALAVLTVVGTLPVLAAAVAVDRVFAALLAGTLAAALLAIVLVG--SE
MSMEG_3241|M.smegmatis_MC2_155      RPVATTVVSALGTVPLLCVSATADRVPAVLLIAGLAAAALAVAAIG--DR
MAB_4509c|M.abscessus_ATCC_199      DDITSSVMIAVASSPVLYGALFFPVWPLGVLVPVGVAVVMGAVLLL----
Mb0086|M.bovis_AF2122/97            SVLAATGLRDLDLLGGLARRMPATTVFFGVAALGACGLPLGAGFVSEWLL
Rv0083|M.tuberculosis_H37Rv         SVLAATGLRDLDLLGGLARRMPATTVFFGVAALGACGLPLGAGFVSEWLL
MUL_1895|M.ulcerans_Agy99           GLLLIGYGAKVGLAPFHGWLADAHSQAPAPVSALMSGVLLSVAFSV----
MAV_4863|M.avium_104                FGPAQVMLAAAGVTAWSLIALMAPSAERERLAGFFTATAVLGAAVL----
                                                                        .  :          

Mflv_3578|M.gilvum_PYR-GCK          LPGV-DGVVRRVFAVTSAIAALIAVTTAFDGRVGGPVLLAMAVVVAIAV-
Mvan_2837|M.vanbaalenii_PYR-1       LPGV-AGVVRQVFSATSAVAALIAVTVAFDGMIAGPVLLAMAVVVALVG-
TH_4594|M.thermoresistible__bu      VELVRTGPLRRILSVWAAVAALIAVTVAFDAPVAAPVLLAMATVVAVAG-
MMAR_3960|M.marinum_M               LPTI----FTRVLAAWSAISALVAVTVAFDGHVEGPILLALAIVVAIAG-
MSMEG_3241|M.smegmatis_MC2_155      LPGI-GAPVRRVWAATSAAAALIAVLVAFDGTVAAPVLLAMSIAIAVGG-
MAB_4509c|M.abscessus_ATCC_199      -VGALPVHARITVAAVAGVALLQASVDGARDALLAVVLLAIALSCCAIGY
Mb0086|M.bovis_AF2122/97            VQSLIHAAPGHDPIVALTTPLAVGVVALATGLSVAAMTKAFGIGFLARPR
Rv0083|M.tuberculosis_H37Rv         VQSLIHAAPGHDPIVALTTPLAVGVVALATGLSVAAMTKAFGIGFLARPR
MUL_1895|M.ulcerans_Agy99           -----------LIRLRPVIDAAVGPGYLRAGLLTVGLTTVLIAAFLLTV-
MAV_4863|M.avium_104                LAAGAELLWHITPVALGCGLIVAALLVTVEAAPLSALWARFPLPVIPAP-
                                                           .            :   :         

Mflv_3578|M.gilvum_PYR-GCK          ------GRDVVGRWVAIGFAVIGAAAHLSYAPLAVLLQPVEVSTATGIST
Mvan_2837|M.vanbaalenii_PYR-1       ------RRDEVARWAAIGFAVVGAGVHLSYSPPSMLLEATRISAAAGIST
TH_4594|M.thermoresistible__bu      ------RHDRTARWIALGFAVVGGLYYLGVAPPYRVLRPIAVAAPTAVAV
MMAR_3960|M.marinum_M               ------RHDRMALWAAAGFGIVGLGLYYSYAPLHALLTATVMPTSIAVST
MSMEG_3241|M.smegmatis_MC2_155      ------QRDPVGRCAAIGFALIGAMFYLDHAAPAMLVEATPLDGPTVASV
MAB_4509c|M.abscessus_ATCC_199      -----QLRDRVALVLGQVFGGLGAAVYLAYVRPELLTDSASAVLYAGPLL
Mb0086|M.bovis_AF2122/97            STQAEAAREAPASMRAGMAIAAGACLVLAVAPLLVAPMVRRAAATLPAAQ
Rv0083|M.tuberculosis_H37Rv         STQAEAAREAPASMRAGMAIAAGACLVLAVAPLLVAPMVRRAAATLPAAQ
MUL_1895|M.ulcerans_Agy99           ---------VTDLKRMLAYSSMENMGLIAIAAAAGTKLAIAALLLHVLAH
MAV_4863|M.avium_104                ------GDPTPSAPPLPVLEDLPRRVRIGDAHQSGFIAAAVLLSALGSVA
                                                                                      

Mflv_3578|M.gilvum_PYR-GCK          LVSSLLLATAAVTIVWMWDRT----ETALWVGAAV---VTVYAVTSCTVT
Mvan_2837|M.vanbaalenii_PYR-1       LVSAVLLAAAAVAVVWAWDHTGGATGLAIWIVPAA---VVVYAVTSFTVT
TH_4594|M.thermoresistible__bu      LIASVLLICCVVAIVWTWRAHVPAAGPLPWLGAAT---VLLYAVTTFTVT
MMAR_3960|M.marinum_M               LAASLLSIAFVVAMSRACAGIGGQNRDIRRILAAVGGVLVIYAVTAFTVT
MSMEG_3241|M.smegmatis_MC2_155      VIGSVMLIGAAAANGWTWSRTVSDTEVVRLVWVAVS-AVIGYAATALTVT
MAB_4509c|M.abscessus_ATCC_199      VIASVLMAATVGMVLATMARVGWASPQSAPTRAVLAGVSMLYSGTAAVVL
Mb0086|M.bovis_AF2122/97            AVKFTGLGAVVRLPAMSGSIAPGVIAAAVLAAALAVAVLARWRFRRRPAP
Rv0083|M.tuberculosis_H37Rv         AVKFTGLGAVVRLPAMSGSIAPGVIAAAVLAAALAVAVLARWRFRRRPAP
MUL_1895|M.ulcerans_Agy99           GIGKTVLFLAGGQLQSAHDSASIADITAVLSRSRVVGVSFAVGVVVLLGL
MAV_4863|M.avium_104                IALRPETLSAAGWYVVGATAATSVLRARVWDSAACK---AWLLAQPYLAA
                                                                                      

Mflv_3578|M.gilvum_PYR-GCK          AGMLVIGGDGGFYAGHMVATILWIAMAAVLFWYAARLP-REDRSVPLGGG
Mvan_2837|M.vanbaalenii_PYR-1       AGMLIGGGDGGFYAGHMAATICWIAMAAALFGYAARLP-REDRSMLIGGG
TH_4594|M.thermoresistible__bu      AGVLAGGVGGGFFAGHMAATICWIGLAAALLWYAARRP-RADRAMPLGGG
MMAR_3960|M.marinum_M               AGVLIAGTEAGFLAGHMAATICWIAVAAALFVYALRVADRERRTAPIGAG
MSMEG_3241|M.smegmatis_MC2_155      VGVALGGAEVGFLAGHMAATLSWIVAAALAFGYAARRP-GASRSVLIGGG
MAB_4509c|M.abscessus_ATCC_199      SGTALLGNNDGFLLGHGLATVSWMAVSVALLLAGLRRY--RGRSWVTRTG
Mb0086|M.bovis_AF2122/97            ARLPLWACGAADLTVRMQYTATSFAEPLQRVFGDVLRP-DTDIEVTHTAE
Rv0083|M.tuberculosis_H37Rv         ARLPLWACGAADLTVRMQYTATSFAEPLQRVFGDVLRP-DTDIEVTHTAE
MUL_1895|M.ulcerans_Agy99           PPFAMFSSEVSIARSLANSGLAWVLGVTLLLMVVAFAALVANSRRMLLGA
MAV_4863|M.avium_104                GVLLVLYTATGRYAGALGAVLVLLALVAVWIVVALNPG---------IAA
                                              .            .      .                   

Mflv_3578|M.gilvum_PYR-GCK          LGLVAAAMAKLFLFDLGTLDGIFRVVVFIVVGLTLLGIGAGYARLLERQD
Mvan_2837|M.vanbaalenii_PYR-1       LGLVAAAMAKLFLFDLGTLDGIFRVAVFIVVGLILLGMGAGYARLLEKQD
TH_4594|M.thermoresistible__bu      LALVAAAVAKLFLFDLGTLDGIFRVVVFIVVGLVLLGTGGGYARWLTHAA
MMAR_3960|M.marinum_M               LALTGAATAKLFLFDLATLDGIFRVAAFIVVGLVLLAMGTGYARSLAR--
MSMEG_3241|M.smegmatis_MC2_155      LVLVAAATGKLFLFDLGTLDGMYRVVLFIVGGLVLLGMGAGYARFLAQQS
MAB_4509c|M.abscessus_ATCC_199      FVLAAMAVAKLFLFDLATLDGVARIGAFIVTGLLLLGGGTLYAREYATRS
Mb0086|M.bovis_AF2122/97            SRYMAERITYRTAVADAIEQRLYTPVVGAVAAMAELLRRAHTGSVHRYLA
Rv0083|M.tuberculosis_H37Rv         SRYMAERITYRTAVADAIEQRLYTPVVGAVAAMAELLRRAHTGSVHRYLA
MUL_1895|M.ulcerans_Agy99           ASEGAPRIAVPATVAAALVTGVVACIALGVTAGPLGGLFDAAAGQFGAN-
MAV_4863|M.avium_104                PESYSLPVRRLVGFVATGLDASLIPVMAFVVGLFGWVLDR----------
                                        .        .               * .                  

Mflv_3578|M.gilvum_PYR-GCK          KQAATRTFDTT-----------
Mvan_2837|M.vanbaalenii_PYR-1       KKL-------------------
TH_4594|M.thermoresistible__bu      GESHPAGESRGTGKHQADNEPV
MMAR_3960|M.marinum_M               ----------------------
MSMEG_3241|M.smegmatis_MC2_155      DGRSDAQPGTDHEAHST-----
MAB_4509c|M.abscessus_ATCC_199      EEPSAERPVT------------
Mb0086|M.bovis_AF2122/97            YGALGVLIVLVVARCT------
Rv0083|M.tuberculosis_H37Rv         YGALGVLIVLVVAR--------
MUL_1895|M.ulcerans_Agy99           ----------------------
MAV_4863|M.avium_104                ----------------------