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PKRSLLAQARPESGSGEYVLGTWRAAALSMAVIAPAAWYGLGALLGAAVMIPVIYALARLRRHAPQARST AELIGAMLGRKAGTAAGIVQLLAYLVLAAQFAATLGLQLLQLLSPGDDPAAIVSWLPVGAAAAALVVGAT ACWASTRAVASLAMPLVLAGLLLYVCLAVAVTALVTLSTDPVVIGSAATPRPLSGQLVGFGLGMVGVELL TVRTPRIARPGRSMSLATAVVAAAAVVLWVGDHRGVAGPWRWSATMLAEAVPEFYTDEGRRWMAAAGIAL AVAAALVTGWAATRAAAGLAAMRGATPNAGLRLTVMGLVAVVAVVVSAHGMRSIGMVILGAAPLLLMALY VLVAEANSRIPGDSVVAWWVRLVMPALAVVAVVKPLVDSQFAPVQVATVVAAAIGVGAAGAAPLLARHRE RTAKSE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4116 | - | - | 100% (427) | hypothetical protein MAV_4116 |
| M. avium 104 | MAV_4427 | - | 5e-06 | 26.39% (288) | efflux ABC transporter, permease protein |
| M. avium 104 | MAV_4611 | menA | 4e-05 | 28.57% (224) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0088 | hycP | 2e-05 | 25.13% (187) | hydrogenase HycP |
| M. gilvum PYR-GCK | Mflv_3578 | - | 1e-09 | 28.49% (358) | hypothetical protein Mflv_3578 |
| M. tuberculosis H37Rv | Rv0085 | hycP | 2e-05 | 25.13% (187) | hydrogenase HycP |
| M. leprae Br4923 | MLBr_02529 | - | 6e-05 | 26.00% (300) | hypothetical protein MLBr_02529 |
| M. abscessus ATCC 19977 | MAB_4909 | - | 1e-05 | 19.40% (397) | GABA permease GabP |
| M. marinum M | MMAR_2052 | - | 1e-06 | 24.88% (410) | amino acid transporter |
| M. smegmatis MC2 155 | MSMEG_5822 | - | 2e-43 | 33.73% (418) | hypothetical protein MSMEG_5822 |
| M. thermoresistible (build 8) | TH_3095 | - | 2e-06 | 26.50% (351) | PUTATIVE putative ABC transporter, membrane spanning protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2837 | - | 2e-09 | 27.32% (366) | hypothetical protein Mvan_2837 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3578|M.gilvum_PYR-GCK -MADMTEPHSAVIARLSADFAAISHQLTRVSGDLAALDRILTDRAPAAAA
Mvan_2837|M.vanbaalenii_PYR-1 ----MTEPHTAVITRLSADFAAISRQLARVSTDLVELDRILADRPQSAPA
Mb0088|M.bovis_AF2122/97 ----MSNANFSILVDFAAGGLVLASVLIVWRRDLRAIVRLLAWQ------
Rv0085|M.tuberculosis_H37Rv ----MSNANFSILVDFAAGGLVLASVLIVWRRDLRAIVRLLAWQ------
MLBr_02529|M.leprae_Br4923 -------MVYVFAEEFCEGPVTSGAVMPIVRVAILADSRLIEMALPTELP
TH_3095|M.thermoresistible__bu --------VSLAHRAWLLGAFGLAALLASIAVAVTIGPSTVGAG------
MAV_4116|M.avium_104 ------MPKRSLLAQARPESGSGEYVLGTWRAAALSMAVIAPAAWYG---
MSMEG_5822|M.smegmatis_MC2_155 -------MTKSARAAARSAAADHAPPVPMWCAVGLSLAMIGSAAFNG---
MMAR_2052|M.marinum_M MSEGPQRRAEAAPATLAASALRPRNVLAIAVSAISPTTSVFLIYGDGLQI
MAB_4909|M.abscessus_ATCC_1997 ------MATTAAPSEGGLQHSLQKRHLTMIAIGGVIGAGLFVGSGATIQA
:
Mflv_3578|M.gilvum_PYR-GCK PR------------PAPQPAAYWPQYP-PQPAPFRPWPQAPAPAPTQALT
Mvan_2837|M.vanbaalenii_PYR-1 PWPQPVSVPSPVPVPSPVPVAQPVPVPSPAPVPQPVAPYRPAYPAYPAYP
Mb0088|M.bovis_AF2122/97 --------------------------------------------------
Rv0085|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02529|M.leprae_Br4923 LR------------------------------------------------
TH_3095|M.thermoresistible__bu --------------------------------------------------
MAV_4116|M.avium_104 --------------------------------------------------
MSMEG_5822|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2052|M.marinum_M AG------------------------------------------------
MAB_4909|M.abscessus_ATCC_1997 AG------------------------------------------------
Mflv_3578|M.gilvum_PYR-GCK PAP---RKERSEGWIGKLLAVAGVAVTLIGVVLLLVLAAQAGILRPEFRV
Mvan_2837|M.vanbaalenii_PYR-1 PASARVRKERSDGWIGKLLAVAGVAVTLIGVVLLLVLAAQAGILRPEFRV
Mb0088|M.bovis_AF2122/97 --------------------------------------------------
Rv0085|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02529|M.leprae_Br4923 ---------------EILPAVKRLVVPAASDNDSPLAANASLHLSLAPIG
TH_3095|M.thermoresistible__bu ----------------------------------------------EVWA
MAV_4116|M.avium_104 -----------------------------------------------LGA
MSMEG_5822|M.smegmatis_MC2_155 -----------------------------------------------VGV
MMAR_2052|M.marinum_M -------------------------------------------TGVVWAF
MAB_4909|M.abscessus_ATCC_1997 -------------------------------------------PAAFLTY
Mflv_3578|M.gilvum_PYR-GCK SAGGALAAALVGAGWWLNTRPGGRVGAIALVATGVAAAYMDVIAVTTIYD
Mvan_2837|M.vanbaalenii_PYR-1 AAGAVLAGALVAAGWWLNGRPGGRVGAIALVATGVAAAYMDVIAVTTIYE
Mb0088|M.bovis_AF2122/97 --GAALAAIPLLRGIRDNDR--------ALIAVGIAVLALRALVLP----
Rv0085|M.tuberculosis_H37Rv --GAALAAIPLLRGIRDNDR--------ALIAVGIAVLALRALVLP----
MLBr_02529|M.leprae_Br4923 GAPFSLDASLDTVGVVDGDLLALQPVPVGPAAPGIVEDIADAAMIFSTAR
TH_3095|M.thermoresistible__bu VVRARLAGPPSGLTRIQEGIVWDLRLPRSLLAAACGAGLAVCGVILQS--
MAV_4116|M.avium_104 LLGAAVMIPVIYALARLRRHAPQARSTAELIGAMLGRKAGTAAGIVQLLA
MSMEG_5822|M.smegmatis_MC2_155 LCATVLVAVVIVALTRLHASAAGAATTSELLGSVLGPVSARFTGLVQLAA
MMAR_2052|M.marinum_M VIGSAIAVCMALCYAEVGSVFPSAGGAYTIVRRAIGPVAGGVTSVLFLLL
MAB_4909|M.abscessus_ATCC_1997 AITGVLIVLVMRMLGEMAVANPSTGSFADYSRRALGDWAGFSVGWLYWYF
:
Mflv_3578|M.gilvum_PYR-GCK WVPAPAGLVLAAVIAGAGLTLARRWDSEHLGLLVLVPLIVLAPIVTDGVS
Mvan_2837|M.vanbaalenii_PYR-1 WTSAPAGLVFASLIAGGGLTLARRWDSEHLGLLVLVPLIGLAPIVTDGIS
Mb0088|M.bovis_AF2122/97 ------------------WLLARAVGAEAAAQREATPLVN-----TASSL
Rv0085|M.tuberculosis_H37Rv ------------------WLLARAVGAEAAAQREATPLVN-----TASSL
MLBr_02529|M.leprae_Br4923 LQSWGPTHIRRGALAATTAVTFAATGLGVTYRAVTGALTGLLVVIVIAVL
TH_3095|M.thermoresistible__bu --------MLRNPLADPFLLGVSSGASTGAVSIVVLGVGAGSIGLAGGAF
MAV_4116|M.avium_104 Y------LVLAAQFAATLGLQLLQLLSPGDDPAAIVSWLPVGAAAAALVV
MSMEG_5822|M.smegmatis_MC2_155 Y------AALGVGAAVSLGLQPLGMAGVDPETVLTSWLWPMWAGIGVIVA
MMAR_2052|M.marinum_M G-----VVSTAAILVAAATYLSSLIGAAVPVRWLALGMMALITALSIGKI
MAB_4909|M.abscessus_ATCC_1997 W------VIVVGFEAVAGGKLIQDWLPHAPLWLIALLLMLAMTATNLFSV
Mflv_3578|M.gilvum_PYR-GCK LLLVGFMLALAAVSLPVQLGKDWIWLHAARIAAAVLPLLVALAARHID-S
Mvan_2837|M.vanbaalenii_PYR-1 LLLVGFMLALAAVSLPVQLGKDWIWLHAARIAAAALPVLTALLARHFESA
Mb0088|M.bovis_AF2122/97 LITAGLTLTAFAITQPVVNLEPGVTINAVPAAFAVVLIALFVMTTRLH--
Rv0085|M.tuberculosis_H37Rv LITAGLTLTAFAITQPVVNLEPGVTINAVPAAFAVVLIALFVMTTRLH--
MLBr_02529|M.leprae_Br4923 IALGGLVLRSRAARTGLVLSIAALVPIGAVFALAVPGIFGPAQVLLAS--
TH_3095|M.thermoresistible__bu IGAVGAFGLVLLLTVAAGGGTDRVILAGVATTQLFSALTSFIVFTAAD--
MAV_4116|M.avium_104 GATACWASTRAVASLAMPLVLAGLLLYVCLAVAVTALVTLSTDPVVIG--
MSMEG_5822|M.smegmatis_MC2_155 GTLVAVLPTRTVMAAVAVLAGLGLLAYFYLALAVIAKMASGSPQVMGG--
MMAR_2052|M.marinum_M APASWVVAAMLALELAVIIVFTVVAFAHASAVTKPFTQPVTAGPGGALVG
MAB_4909|M.abscessus_ATCC_1997 RSYGEFEYWFASVKVAAIVAFLVAGTCYVLGLWPGKKLDFSNLTVHEG--
Mflv_3578|M.gilvum_PYR-GCK REDLWLAGACGIAAVIALTAALILLPGTGNRVVMALLTVAGIVPVLCVNL
Mvan_2837|M.vanbaalenii_PYR-1 RQDLWLAGASGIAAAVALVAALILLPGTKNRAAMALLTAAGVLPVLCVSL
Mb0088|M.bovis_AF2122/97 --------------AVSQAAGFLMLDN--GIAATAFLLTAGVPLIVELGA
Rv0085|M.tuberculosis_H37Rv --------------AVSQAAGFLMLDN--GIAATAFLLTAGVPLIVELGA
MLBr_02529|M.leprae_Br4923 ------------AGVTAWSLIALIVPGPERVRIVAFFTATVVIGVAVMLE
TH_3095|M.thermoresistible__bu --------AEQTRGVLFWLLGSLASASWRDVAVVTALVAAGLVACLVWAS
MAV_4116|M.avium_104 -----------SAATPRPLSGQLVGFGLGMVGVELLTVRTPRIARPGRSM
MSMEG_5822|M.smegmatis_MC2_155 ----------TESISTVDMLAAALPLGLSLFGFEAPTAASDRLRSVARPL
MMAR_2052|M.marinum_M ---------VGIAGIFAAVGPALFAFNGYDWPLYFSEETAGSRRAIPHAV
MAB_4909|M.abscessus_ATCC_1997 ------FMPHGPGAIFSSIVIVIFSMVGAEIATIAAAESKDPAKAISQAT
Mflv_3578|M.gilvum_PYR-GCK AVDRVVAALMAAALAAALLAVALLADRLPGVDGVVRRVFAVTSAIAALIA
Mvan_2837|M.vanbaalenii_PYR-1 AVDRVVAALMAATLAAALLAIVLFGERLPGVAGVVRQVFSATSAVAALIA
Mb0088|M.bovis_AF2122/97 SLDVLFAVIVIGVLT-----------------GRLRRIFG-DADLDKLRE
Rv0085|M.tuberculosis_H37Rv SLDVLFAVIVIGVLT-----------------GRLRRIFG-DADLDKLRE
MLBr_02529|M.leprae_Br4923 AGAALLWQLTPLTIG----------------CGLILAALLVTVEAAQLSA
TH_3095|M.thermoresistible__bu SLDSFTFGEDAAAGLG---------------VRVGPTRLGLLLVTASMTA
MAV_4116|M.avium_104 SLATAVVAAAAVVLWVG-----------DHRGVAGPWRWSATMLAEAVPE
MSMEG_5822|M.smegmatis_MC2_155 GVAVGITAVCAVVLLVAVN-----------LSTIAGFSHRATDLPLIVPE
MMAR_2052|M.marinum_M VLSAVLAVVVECVAVIAAT-------------LAIRDIPAAITDGSAVEF
MAB_4909|M.abscessus_ATCC_1997 NSVIYRVAIFFVGSIFLIA----------VIVPWNSPELGTSPYVTAFKT
.
Mflv_3578|M.gilvum_PYR-GCK VTTAFDGRVGGPVLLAMAVVVAIAVGRDVVGRWVAIGFAVIGAAAHLSYA
Mvan_2837|M.vanbaalenii_PYR-1 VTVAFDGMIAGPVLLAMAVVVALVGRRDEVARWAAIGFAVVGAGVHLSYS
Mb0088|M.bovis_AF2122/97 LRD-----------------------------------------------
Rv0085|M.tuberculosis_H37Rv LRD-----------------------------------------------
MLBr_02529|M.leprae_Br4923 LWARFPLPVIPAPGDPTPSAPSFQVLEDLPRR---VRISSAHQSGFIAAA
TH_3095|M.thermoresistible__bu VIVSTSGAIG------------------------FVGLVLPHVARALVGV
MAV_4116|M.avium_104 FYTDEGRRWMAAAGIALAVAAALVTGWAATRAAAGLAAMRGATPNAGLRL
MSMEG_5822|M.smegmatis_MC2_155 LFGDMGRQSLNLASALLGVAVVLATMWAATR--VAARLFGGGVVTAVSVP
MMAR_2052|M.marinum_M LARQMMGPAGATVLVAGVVVAMFDTGLAANLG--YARVYYAAARDGMLPR
MAB_4909|M.abscessus_ATCC_1997 MGIPAADHIMRVVVLTAVLSCLNSAMYTASRMLFVLAGRGEAPRSWLKVN
.
Mflv_3578|M.gilvum_PYR-GCK PLAVLLQPVEVSTATGISTLVSSLLLATAAVTIVWMWDRT----ETALWV
Mvan_2837|M.vanbaalenii_PYR-1 PPSMLLEATRISAAAGISTLVSAVLLAAAAVAVVWAWDHTGGATGLAIWI
Mb0088|M.bovis_AF2122/97 --------------------------------------------------
Rv0085|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02529|M.leprae_Br4923 TLLSMLGSVAIALRPEAVSSVGWYLVAATAVAATLR---------ARVWD
TH_3095|M.thermoresistible__bu AHRRLLPLSAVIG-------------------------------------
MAV_4116|M.avium_104 TVMGLVAVVAVVVSAHGMRSIGMVILGAAP--------------------
MSMEG_5822|M.smegmatis_MC2_155 AVMCVLTVVACRFPEDIGELLFVVP-------------------------
MMAR_2052|M.marinum_M RLQPLFGRLSTRSRVPVHGFLFLFLGNGLLCVFMSLP-------------
MAB_4909|M.abscessus_ATCC_1997 ARGVPVQAILASSFIGFVCVILAYFFEHTVFLFLLNS-------------
Mflv_3578|M.gilvum_PYR-GCK GAAVVTVYAVTSCTVTAGMLVIGGDGGFYAGHMVATILWIAMAAVLFWYA
Mvan_2837|M.vanbaalenii_PYR-1 VPAAVVVYAVTSFTVTAGMLIGGGDGGFYAGHMAATICWIAMAAALFGYA
Mb0088|M.bovis_AF2122/97 --------------------------------------------------
Rv0085|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02529|M.leprae_Br4923 SVACKAWLLAQPYLVASVLLGLYTATGRYVAASAALLVLVVVVLAWAVVA
TH_3095|M.thermoresistible__bu ---------------------------------AVFLVWVDTVAR-----
MAV_4116|M.avium_104 --------LLLMALYVLVAEANSRIPGDSVVAWWVRLVMPALAVVAVVKP
MSMEG_5822|M.smegmatis_MC2_155 -------ALLLFVVYVAVGEANARVAGSPVAMQLPRAVLVVVLLAVLLIS
MMAR_2052|M.marinum_M KLITFTGVVIAIVYLLVALSAIVCRLRDRDLVRPFRMPLWPLPPLLAVVG
MAB_4909|M.abscessus_ATCC_1997 --SGAVILFVYLMIAISQYVLRRRTPEEKLLVKMWGYPALTILTAIGIVA
Mflv_3578|M.gilvum_PYR-GCK AR---LPREDRSVPLGGGLGLVAAAMAKLFLFDLGTLDGIFRVVVFIVVG
Mvan_2837|M.vanbaalenii_PYR-1 AR---LPREDRSMLIGGGLGLVAAAMAKLFLFDLGTLDGIFRVAVFIVVG
Mb0088|M.bovis_AF2122/97 --------------------------------------------------
Rv0085|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02529|M.leprae_Br4923 LNPRIASSDSYSLPLRRLLGMVASGLDASLIPAMAYLVSLFSWVLNR---
TH_3095|M.thermoresistible__bu -----VIIDPQELPVGVATALIGVPVFALILLRRRRAV------------
MAV_4116|M.avium_104 LVDSQFAPVQVATVVAAAIGVGAAGAAPLLARHRERTAKSE---------
MSMEG_5822|M.smegmatis_MC2_155 VREGYFILGSIWPLLVAAVITAAAAIFARTTPRPAHPPR-----------
MMAR_2052|M.marinum_M VVVTLATQEVKDLAIGAGLAAAAALGYRIARRRLPARLGGDPVTGRSTP-
MAB_4909|M.abscessus_ATCC_1997 ILVAMGFQDATRTQLWTSLLSWGVILLLFAILRLTRRRTPEPGERTTR--
Mflv_3578|M.gilvum_PYR-GCK LTLLGIGAGYARLLERQDKQAATRTFDTT
Mvan_2837|M.vanbaalenii_PYR-1 LILLGMGAGYARLLEKQDKKL--------
Mb0088|M.bovis_AF2122/97 -----------------------------
Rv0085|M.tuberculosis_H37Rv -----------------------------
MLBr_02529|M.leprae_Br4923 -----------------------------
TH_3095|M.thermoresistible__bu -----------------------------
MAV_4116|M.avium_104 -----------------------------
MSMEG_5822|M.smegmatis_MC2_155 -----------------------------
MMAR_2052|M.marinum_M -----------------------------
MAB_4909|M.abscessus_ATCC_1997 -----------------------------