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MTESQHAVISRLSAEFDSLARQMARVSGELSQLDRLISDSVGAPQPAAAAPPQPQPQPVAPYWYPYWQQW APVAPAPAAAPPRQYAPPPTARPAPQGPPAPAPAAAPPVSAPRRPAESTESGWIGKLLAVAGVAVTLTGV ALLLVLAAQAGLLRPEIRVAGGTALSLALVGVAVRLRGRPGGRIGAIALAATGIATAYLDVIAATTIYQW VPAPAGLVLAALVGGAGLALARRWDSEHLGLLVLVPLIGLAPVLTRGADLLLVSFMLALSAAALPVQLGK DWVWLHAARVAAPTVPLLIALVAAGKHDNTWLLGAACGVAAILAIVSGLIVLPGGKNAAALAVLTVVGTL PVLAAAVAVDRVFAALLAGTLAAALLAIVLVGSELPTIFTRVLAAWSAISALVAVTVAFDGHVEGPILLA LAIVVAIAGRHDRMALWAAAGFGIVGLGLYYSYAPLHALLTATVMPTSIAVSTLAASLLSIAFVVAMSRA CAGIGGQNRDIRRILAAVGGVLVIYAVTAFTVTAGVLIAGTEAGFLAGHMAATICWIAVAAALFVYALRV ADRERRTAPIGAGLALTGAATAKLFLFDLATLDGIFRVAAFIVVGLVLLAMGTGYARSLAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3960 | - | - | 100% (621) | hypothetical protein MMAR_3960 |
| M. marinum M | MMAR_0602 | - | 2e-08 | 47.67% (86) | hypothetical protein MMAR_0602 |
| M. marinum M | MMAR_4294 | - | 3e-08 | 41.00% (100) | hypothetical protein MMAR_4294 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1031c | - | 8e-11 | 26.65% (364) | hypothetical protein Mb1031c |
| M. gilvum PYR-GCK | Mflv_3578 | - | 1e-178 | 56.62% (627) | hypothetical protein Mflv_3578 |
| M. tuberculosis H37Rv | Rv1004c | - | 9e-11 | 26.65% (364) | hypothetical protein Rv1004c |
| M. leprae Br4923 | MLBr_00431 | - | 2e-05 | 30.51% (118) | hypothetical protein MLBr_00431 |
| M. abscessus ATCC 19977 | MAB_4509c | - | 6e-79 | 33.97% (624) | hypothetical protein MAB_4509c |
| M. avium 104 | MAV_2254 | - | 2e-09 | 32.03% (128) | hypothetical protein MAV_2254 |
| M. smegmatis MC2 155 | MSMEG_3241 | - | 1e-155 | 49.92% (627) | hypothetical protein MSMEG_3241 |
| M. thermoresistible (build 8) | TH_4594 | - | 1e-104 | 54.98% (402) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4514 | - | 4e-09 | 48.78% (82) | membrane protein |
| M. vanbaalenii PYR-1 | Mvan_2837 | - | 0.0 | 57.69% (631) | hypothetical protein Mvan_2837 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1031c|M.bovis_AF2122/97 --------------------------------------------------
Rv1004c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3578|M.gilvum_PYR-GCK MADMTEPHSAVIARLSADFAAISHQLTRVSGDLAALDRILTD-----RAP
Mvan_2837|M.vanbaalenii_PYR-1 ---MTEPHTAVITRLSADFAAISRQLARVSTDLVELDRILAD-----RPQ
TH_4594|M.thermoresistible__bu --------------------------------------------------
MSMEG_3241|M.smegmatis_MC2_155 ---MTEPQRAVIARVTADLTAVSAYLNRMAGDLATLDRLVAQ-----QSA
MMAR_3960|M.marinum_M ---MTESQHAVISRLSAEFDSLARQMARVSGELSQLDRLISDSVGAPQPA
MAB_4509c|M.abscessus_ATCC_199 ----MFTSHRTASTLRGMSDPQLQQMTATLDELDGRERALRAEVDALRGR
MLBr_00431|M.leprae_Br4923 --------------------------------------------------
MUL_4514|M.ulcerans_Agy99 --------------------------------------------------
MAV_2254|M.avium_104 --------------------------------------------------
Mb1031c|M.bovis_AF2122/97 --------------------------------------------------
Rv1004c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3578|M.gilvum_PYR-GCK AAAAPR-------------------PAPQPAAYWPQYP-PQPAPFRPWPQ
Mvan_2837|M.vanbaalenii_PYR-1 SAPAPWPQPVSVP-------SPVPVPSPVPVAQPVPVPSPAPVPQPVAPY
TH_4594|M.thermoresistible__bu --------------------------------------------------
MSMEG_3241|M.smegmatis_MC2_155 APRPE-------------------AVAPQWSPQAPQQPPRQWTPQPVAPV
MMAR_3960|M.marinum_M AAAPPQPQPQPVAPYWYPYWQQWAPVAPAPAAAPPRQYAPPPTARPAPQG
MAB_4509c|M.abscessus_ATCC_199 MVEWTQAEYLKAQR------------YWDDYRRAQGVAQAVAPAPVVMPP
MLBr_00431|M.leprae_Br4923 --------------------------------------------------
MUL_4514|M.ulcerans_Agy99 --------------------------------------------------
MAV_2254|M.avium_104 --------------------------------------------------
Mb1031c|M.bovis_AF2122/97 ------------------------------MSISCRVREGFVMRLAIVGT
Rv1004c|M.tuberculosis_H37Rv ------------------------------MSISCRVREGFVMRLAIVGT
Mflv_3578|M.gilvum_PYR-GCK APAPAPTQALTPAP---RKERSE-GWIGKLLAVAGVAVTLIGVVLLLVLA
Mvan_2837|M.vanbaalenii_PYR-1 RPAYPAYPAYPPASARVRKERSD-GWIGKLLAVAGVAVTLIGVVLLLVLA
TH_4594|M.thermoresistible__bu --------------------------------------------------
MSMEG_3241|M.smegmatis_MC2_155 APVAVPARQPDTPP----KPRSE-GWIGKVLAMAGVAVTLVGVVSLLVLA
MMAR_3960|M.marinum_M PPAPAPAAAPPVSAPRRPAESTESGWIGKLLAVAGVAVTLTGVALLLVLA
MAB_4509c|M.abscessus_ATCC_199 ARMPVPARAPHPAPPQLEPWWMREGFASKAMALAGAVVTLAGVVMLLVLA
MLBr_00431|M.leprae_Br4923 --------------------------------------------------
MUL_4514|M.ulcerans_Agy99 ------------------------------MRIGGRWVAHPAVASVRQRA
MAV_2254|M.avium_104 --------------------------------------------------
Mb1031c|M.bovis_AF2122/97 AAAAAIGGTLAVAPLTLSTPERVAGGTCSAGQQCDRLAAVLMPDTATPSG
Rv1004c|M.tuberculosis_H37Rv AAAAAIGGTLAVAPLTLSTPERVAGGTCSAGQQCDRLAAVLMPDTATPSG
Mflv_3578|M.gilvum_PYR-GCK AQAGILRPEFRVSAGGALAAALVGAGWWLNTRPGGRVGAIALVATGVAAA
Mvan_2837|M.vanbaalenii_PYR-1 AQAGILRPEFRVAAGAVLAGALVAAGWWLNGRPGGRVGAIALVATGVAAA
TH_4594|M.thermoresistible__bu --------------------------------------------------
MSMEG_3241|M.smegmatis_MC2_155 AQAGILRPEVRVAAGAALAVALVAVAMWLDRRPGGRVGAVALAATGVAAA
MMAR_3960|M.marinum_M AQAGLLRPEIRVAGGTALSLALVGVAVRLRGRPGGRIGAIALAATGIATA
MAB_4509c|M.abscessus_ATCC_199 AKSGYFGPVPRMVSGAALAGGLVALGIRVYSRPGGRVGGIATAATGFAAA
MLBr_00431|M.leprae_Br4923 --------------------------------------------------
MUL_4514|M.ulcerans_Agy99 LRAKTPVFGIAMITPLVFAGAVGATAPASYGKTPAVRAAITPVAAVAPSP
MAV_2254|M.avium_104 --------------------------------MPATLSQIEAWSTEHLID
Mb1031c|M.bovis_AF2122/97 -------------------------PAAAEHA-VPAPFEP---VADTIAP
Rv1004c|M.tuberculosis_H37Rv -------------------------PAAAEHA-VPAPFEP---VADTIAP
Mflv_3578|M.gilvum_PYR-GCK YMDVIAVTTIYDWVPAPAGLVLAAVIAGAGLT-LARRWDSEHLGLLVLVP
Mvan_2837|M.vanbaalenii_PYR-1 YMDVIAVTTIYEWTSAPAGLVFASLIAGGGLT-LARRWDSEHLGLLVLVP
TH_4594|M.thermoresistible__bu -------------------------------M-LARRWDSEHLGLLVLVP
MSMEG_3241|M.smegmatis_MC2_155 YMDVIAVTAIYEWVPAPVGLALAGVVGACGLM-LARWWGSEQLGLLVFVP
MMAR_3960|M.marinum_M YLDVIAATTIYQWVPAPAGLVLAALVGGAGLA-LARRWDSEHLGLLVLVP
MAB_4509c|M.abscessus_ATCC_199 FFDVLALTVIYDRIPVVAGLVLGLGIAGVGLV-LARHWNSQPFASGVVAA
MLBr_00431|M.leprae_Br4923 ---------------------------MNNPR-RSEWLGPSLAGSGPIEP
MUL_4514|M.ulcerans_Agy99 AIDLSGPSIVAVERPPTNFHIAAGTTAAPPPARVVNAPGALGIPIMALTA
MAV_2254|M.avium_104 --------------------------AAAYWTQTADRWEDAFLTMRNQAQ
Mb1031c|M.bovis_AF2122/97 GLVPRPGVPAAAAVPR-VGPPAVPGLPNIPGAAG-------PALPPPPAL
Rv1004c|M.tuberculosis_H37Rv GLVPRPGVPAAAAVPR-VGPPAVPGLPNIPGAAG-------PALPPPPAL
Mflv_3578|M.gilvum_PYR-GCK LIVLAPIVTDGVSLLL-VGFMLALAAVSLPVQLGKDWIWLHAARIAAAVL
Mvan_2837|M.vanbaalenii_PYR-1 LIGLAPIVTDGISLLL-VGFMLALAAVSLPVQLGKDWIWLHAARIAAAAL
TH_4594|M.thermoresistible__bu LVLLAPVITDGITVVL-IGFMLALGAASLPVQLGRDWIWLHAARTASVTL
MSMEG_3241|M.smegmatis_MC2_155 LIALAPVITDGVTLLL-IGFMLALSAASLPVQFGRDWFWLHAARTAAVTI
MMAR_3960|M.marinum_M LIGLAPVLTRGADLLL-VSFMLALSAAALPVQLGKDWVWLHAARVAAPTV
MAB_4509c|M.abscessus_ATCC_199 ITVLAPFLTDGFTVEL-AAFALILLIASLTAQVGRNWPVLHAFRTVGVSL
MLBr_00431|M.leprae_Br4923 QVHQYPPLTDPAYAEQ-APYAPAYGASLPP----------WTPKKPPQQL
MUL_4514|M.ulcerans_Agy99 YRNAEQKMATAAPACG-ISWNLLAGIGRIESMHANG----GAVDERGTAV
MAV_2254|M.avium_104 SITWHGAGGDALRQRTGADLSVVSGKADLLRQAAG------IARNGASDI
:
Mb1031c|M.bovis_AF2122/97 PNLAAPSVPGVG--IPGIGIPGIGIPGIGIPGVPDPITGVNTAA--AVVN
Rv1004c|M.tuberculosis_H37Rv PNLAAPSVPGVG--IPGIGIPGIGIPGIGIPGVPDPITGVNTAA--AVVN
Mflv_3578|M.gilvum_PYR-GCK PLLVALAARHID-SREDLWLAGACGIAAVIALTAALILLPGTGN--RVVM
Mvan_2837|M.vanbaalenii_PYR-1 PVLTALLARHFESARQDLWLAGASGIAAAVALVAALILLPGTKN--RAAM
TH_4594|M.thermoresistible__bu PILGALLGASFAQDRVPALTA-ACGIAAVLALAAALLLAPSTRN--HTAL
MSMEG_3241|M.smegmatis_MC2_155 PLLVALVSAAIG-GREDLRLALVCALAAVPALVGGVTVSRFSTR--PVAT
MMAR_3960|M.marinum_M PLLIALVAAGKH--DNTWLLGAACGVAAILAIVSGLIVLPGGKN--AAAL
MAB_4509c|M.abscessus_ATCC_199 TLLTAIHVSYTA----SLALLAMSVMALLVTLVGSLWLLTGEHD--DITS
MLBr_00431|M.leprae_Br4923 PRYWQQDQPPPT----------------DIPPEGLTLPPPHEPK--SPHW
MUL_4514|M.ulcerans_Agy99 NPIYGPALDGTLPGNEVIIQSKVGNRVTYARAMGPMQFLPGTWARYASDG
MAV_2254|M.avium_104 SAAQRRVLYGVEDALNAGFTVGEDLSVTDTRSTSPAERAARQAQAEAFAA
Mb1031c|M.bovis_AF2122/97 GVLGVGGTAAGVVTASAVAVTYLVLAVNALESSGILPTARG------TAS
Rv1004c|M.tuberculosis_H37Rv GVLGVGGTAAGVVTASAVAVTYLVLAVNALESSGILPTARG------TAS
Mflv_3578|M.gilvum_PYR-GCK ALLTVAGIVPVLCVNLAVDRVVAALMAAALAAALLAVALLA--DRLPGV-
Mvan_2837|M.vanbaalenii_PYR-1 ALLTAAGVLPVLCVSLAVDRVVAALMAATLAAALLAIVLFG--ERLPGV-
TH_4594|M.thermoresistible__bu GLLTAAGTLPVLCVSWAERPAVSALMAAALSAALLAMAAGAGLIRVELVR
MSMEG_3241|M.smegmatis_MC2_155 TVVSALGTVPLLCVSATADRVPAVLLIAGLAAAALAVAAIG--DRLPGI-
MMAR_3960|M.marinum_M AVLTVVGTLPVLAAAVAVDRVFAALLAGTLAAALLAIVLVG--SELPTI-
MAB_4509c|M.abscessus_ATCC_199 SVMIAVASSPVLYGALFFPVWPLGVLVPVGVAVVMGAVLLL-----VGAL
MLBr_00431|M.leprae_Br4923 FLWVVAGASVVLVVGLVMALIIANGAIKTQTAVPPLPAITE---------
MUL_4514|M.ulcerans_Agy99 DSDGVPDPQNIFDSTLAAARYLCSGGLNLRDPGQVMAAILR---YNNSMP
MAV_2254|M.avium_104 DIRLRAEQLDGADTKVSGQLTAATAGLSGGGFAQNSTSNRG--------G
Mb1031c|M.bovis_AF2122/97 TVASLLLPGAQSAAAALPAVGLPALPGVTPASLLAMAAAAGLP-------
Rv1004c|M.tuberculosis_H37Rv TVASLLLPGAQSAAAALPAVGLPALPGVTPASLLAMAAAAGLP-------
Mflv_3578|M.gilvum_PYR-GCK DGVVRRVFAVTSAIAALIAVTTAFDGRVGGPVLLAMAVVVAIA--VGRDV
Mvan_2837|M.vanbaalenii_PYR-1 AGVVRQVFSATSAVAALIAVTVAFDGMIAGPVLLAMAVVVALV--GRRDE
TH_4594|M.thermoresistible__bu TGPLRRILSVWAAVAALIAVTVAFDAPVAAPVLLAMATVVAVA--GRHDR
MSMEG_3241|M.smegmatis_MC2_155 GAPVRRVWAATSAAAALIAVLVAFDGTVAAPVLLAMSIAIAVG--GQRDP
MMAR_3960|M.marinum_M ---FTRVLAAWSAISALVAVTVAFDGHVEGPILLALAIVVAIA--GRHDR
MAB_4509c|M.abscessus_ATCC_199 PVHARITVAAVAGVALLQASVDGARDALLAVVLLAIALSCCAIGYQLRDR
MLBr_00431|M.leprae_Br4923 --SSSATPTPTTKTSPTPTAGPAPSTTGSGTLTQTIGPSAMLD-------
MUL_4514|M.ulcerans_Agy99 YAQNVLGWAAAYATGVLPVDLPPITGPPPPIGDAHLEHPEGLG-------
MAV_2254|M.avium_104 RAQNSSGNGGQPQPGHNAGQPQPATTNHNGVRLVDFTQDNASG-------
. :
Mb1031c|M.bovis_AF2122/97 -----GVGFPSLPG---VSPTDLMAMAAAAGLPTSLPGLAGMSPAELTAL
Rv1004c|M.tuberculosis_H37Rv -----GVGFPSLPG---VSPTDLMAMAAAAGLPTSLPGLAGMSPAELTAL
Mflv_3578|M.gilvum_PYR-GCK VGRWVAIGFAVIGAAAHLSYAPLAVLLQPVEVSTATGISTLVSSLLLATA
Mvan_2837|M.vanbaalenii_PYR-1 VARWAAIGFAVVGAGVHLSYSPPSMLLEATRISAAAGISTLVSAVLLAAA
TH_4594|M.thermoresistible__bu TARWIALGFAVVGGLYYLGVAPPYRVLRPIAVAAPTAVAVLIASVLLICC
MSMEG_3241|M.smegmatis_MC2_155 VGRCAAIGFALIGAMFYLDHAAPAMLVEATPLDGPTVASVVIGSVMLIGA
MMAR_3960|M.marinum_M MALWAAAGFGIVGLGLYYSYAPLHALLTATVMPTSIAVSTLAASLLSIAF
MAB_4509c|M.abscessus_ATCC_199 VALVLGQVFGGLGAAVYLAYVRPELLTDSASAVLYAGPLLVIASVLMAAT
MLBr_00431|M.leprae_Br4923 ---------------VVYSITGQGRAISVTYMDTGDVIQTEFNVVLPWSK
MUL_4514|M.ulcerans_Agy99 --PNLPLNANGLEPADPLSHMPLIDFAPPQMPAPPPPMFPWMQPTPQPLA
MAV_2254|M.avium_104 --------------------PNPPPFAPWDNPDGAPPAPAPVQPGVIPQL
Mb1031c|M.bovis_AF2122/97 VAGGLPMLAAAG-----------LPAGLAGVDPATLAAALPALAAGGLPP
Rv1004c|M.tuberculosis_H37Rv VAGGLPMLAAAG-----------LPAGLAGVDPATLAAALPALAAGGLPP
Mflv_3578|M.gilvum_PYR-GCK AVTIVWMWDRT-------ETALWVGAAVVTVYAVTSCTVTAGMLVIGGDG
Mvan_2837|M.vanbaalenii_PYR-1 AVAVVWAWDHTG---GATGLAIWIVPAAVVVYAVTSFTVTAGMLIGGGDG
TH_4594|M.thermoresistible__bu VVAIVWTWRAHV---PAAGPLPWLGAATVLLYAVTTFTVTAGVLAGGVGG
MSMEG_3241|M.smegmatis_MC2_155 AAANGWTWSRTVS-DTEVVRLVWVAVSAVIGYAATALTVTVGVALGGAEV
MMAR_3960|M.marinum_M VVAMSRACAGIGGQNRDIRRILAAVGGVLVIYAVTAFTVTAGVLIAGTEA
MAB_4509c|M.abscessus_ATCC_199 VGMVLATMARVGWASPQSAPTRAVLAGVSMLYSGTAAVVLSGTALLGNND
MLBr_00431|M.leprae_Br4923 QVSLSKSAVHPAS-----------VTIVNIGHDVTCSVTVAGVQIRQHTG
MUL_4514|M.ulcerans_Agy99 PQPGCTLICVTNP----------PEAVPPPAPMPFGLMPPPPAPAAPPPP
MAV_2254|M.avium_104 EQSMTAPPAPKPG----------PPASPLPSPSVTPLPNPAAVGPAAAAP
Mb1031c|M.bovis_AF2122/97 GLPALPGVDPAALAAALPALAAGLPALP----AGLPPLPAVPALPAPPPL
Rv1004c|M.tuberculosis_H37Rv GLPALPGVDPAALAAALPALAAGLPALP----AGLPPLPAVPALPAPPPL
Mflv_3578|M.gilvum_PYR-GCK GFYAGHMVATILWIAMAAVLFWYAARLP-REDRSVPLGGGLGLVAAAMAK
Mvan_2837|M.vanbaalenii_PYR-1 GFYAGHMAATICWIAMAAALFGYAARLP-REDRSMLIGGGLGLVAAAMAK
TH_4594|M.thermoresistible__bu GFFAGHMAATICWIGLAAALLWYAARRP-RADRAMPLGGGLALVAAAVAK
MSMEG_3241|M.smegmatis_MC2_155 GFLAGHMAATLSWIVAAALAFGYAARRP-GASRSVLIGGGLVLVAAATGK
MMAR_3960|M.marinum_M GFLAGHMAATICWIAVAAALFVYALRVADRERRTAPIGAGLALTGAATAK
MAB_4509c|M.abscessus_ATCC_199 GFLLGHGLATVSWMAVSVALLLAGLRRY--RGRSWVTRTGFVLAAMAVAK
MLBr_00431|M.leprae_Br4923 --------------------------------------VGLTICDAPR--
MUL_4514|M.ulcerans_Agy99 DPLAPLGVPPVGGPPAAPAPAPAGPPVP-----GGPAPAGPAPAPAGPAP
MAV_2254|M.avium_104 AKPPCSPYDATKAILEPPIGMVGILT-------AVPESLTIAGIPAALTQ
Mb1031c|M.bovis_AF2122/97 PGPPPLPALPSRLCTPGFGPIGVCIP------------------------
Rv1004c|M.tuberculosis_H37Rv PGPPPLPALPSRLCTPGFGPIGVCIP------------------------
Mflv_3578|M.gilvum_PYR-GCK LFLFDLGTLDGIFRVVVFIVVGLTLLGIGAGYARLLERQDKQAATRTFDT
Mvan_2837|M.vanbaalenii_PYR-1 LFLFDLGTLDGIFRVAVFIVVGLILLGMGAGYARLLEKQDKKL-------
TH_4594|M.thermoresistible__bu LFLFDLGTLDGIFRVVVFIVVGLVLLGTGGGYARWLTHAAGESHPAGESR
MSMEG_3241|M.smegmatis_MC2_155 LFLFDLGTLDGMYRVVLFIVGGLVLLGMGAGYARFLAQQSDGRSDAQPGT
MMAR_3960|M.marinum_M LFLFDLATLDGIFRVAAFIVVGLVLLAMGTGYARSLAR------------
MAB_4509c|M.abscessus_ATCC_199 LFLFDLATLDGVARIGAFIVTGLLLLGGGTLYAREYATRSEEPSAERPVT
MLBr_00431|M.leprae_Br4923 --------------------------------------------------
MUL_4514|M.ulcerans_Agy99 APGAPAPAGPAPTPTPSGPAPGEPVLTPVH--------------------
MAV_2254|M.avium_104 IGVGTVAVADGLDAADKCLP------------------------------
Mb1031c|M.bovis_AF2122/97 ------------
Rv1004c|M.tuberculosis_H37Rv ------------
Mflv_3578|M.gilvum_PYR-GCK T-----------
Mvan_2837|M.vanbaalenii_PYR-1 ------------
TH_4594|M.thermoresistible__bu GTGKHQADNEPV
MSMEG_3241|M.smegmatis_MC2_155 DHEAHST-----
MMAR_3960|M.marinum_M ------------
MAB_4509c|M.abscessus_ATCC_199 ------------
MLBr_00431|M.leprae_Br4923 ------------
MUL_4514|M.ulcerans_Agy99 ------------
MAV_2254|M.avium_104 ------------