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VPPDASATKKRLLDAAYAEFAEHGLAGARVDRIGAAAEANKRLLYVYYTNKETLFDIVVAHSIQQMSEAV PFTPEDLPGYAGALFDHLIKHPEHLRLATWAQLERPAAGPAETSAYAAKVAAIAQTGLSAGDVEPADILA LTLGLTTAWLGASPALRGLAASEPFSPERLATHRTALIAAVEALVSAAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3705 | - | - | 100% (190) | TetR family regulatory protein |
| M. abscessus ATCC 19977 | MAB_4389 | - | 1e-24 | 37.84% (185) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0483c | - | 1e-08 | 28.40% (162) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0244 | - | 3e-05 | 32.26% (62) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4072 | - | 2e-07 | 34.18% (79) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0238 | - | 3e-05 | 32.26% (62) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 3e-05 | 40.43% (47) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_3952 | - | 7e-26 | 35.45% (189) | hypothetical protein MMAR_3952 |
| M. avium 104 | MAV_0082 | - | 3e-25 | 34.57% (188) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1305 | - | 8e-25 | 36.41% (195) | TetR family protein regulatory protein |
| M. thermoresistible (build 8) | TH_1911 | - | 1e-05 | 37.29% (59) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1163 | - | 3e-06 | 35.48% (62) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4046 | - | 1e-23 | 37.50% (184) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0244|M.bovis_AF2122/97 --------------MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMD
Rv0238|M.tuberculosis_H37Rv --------------MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMD
MUL_1163|M.ulcerans_Agy99 --------------MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMD
MLBr_02568|M.leprae_Br4923 --------------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMD
TH_1911|M.thermoresistible__bu ------------------------------MLDAAVQMFSVNGYHETSMD
MMAR_3952|M.marinum_M --------------------MRTTAELRETILTAARSEFAQYGLAGARID
MAV_0082|M.avium_104 --------------------MRTATELRGEILQAAGAEFAQYGLAGARID
Mvan_4046|M.vanbaalenii_PYR-1 --------------------MRSTGELRDAILVAARAEFAQYGLAGARID
MAB_3705|M.abscessus_ATCC_1997 -------------------MPPDASATKKRLLDAAYAEFAEHGLAGARVD
MSMEG_1305|M.smegmatis_MC2_155 -------------------MAWDTARTKQKLLDAAVHEFSEHGPLGARVD
Mflv_4072|M.gilvum_PYR-GCK MRHSLIMDAVSGPKSGESLTVRRQRATKARIAAAAAEAVAAHGLAGATIE
: ** .: * : ::
Mb0244|M.bovis_AF2122/97 AIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPK
Rv0238|M.tuberculosis_H37Rv AIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPK
MUL_1163|M.ulcerans_Agy99 TIAAAAQISKPMLYLYYGSKEDLFGACLNREMSRFIDAVRADIDLSQSPK
MLBr_02568|M.leprae_Br4923 AIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPK
TH_1911|M.thermoresistible__bu AIAAQAEISKPMLYLYYGSKEELFGACLKRELSRFVETVRADIDFSQSPK
MMAR_3952|M.marinum_M RIARTAEASKERLYAHFQDKEALFRSVVAADMEEFFAAVTLRPD---AVP
MAV_0082|M.avium_104 RIARVAQASKERLYAHFRDKETLFREVVAAGNREFFSAVTLRPD---AVP
Mvan_4046|M.vanbaalenii_PYR-1 RIAKAAAASKERLYAHFRDKETLFREVLAADGAEFFAAVSLRPD---SVP
MAB_3705|M.abscessus_ATCC_1997 RIGAAAEANKRLLYVYYTNKETLFDIVVAHSIQQMSEAVPFTPE---DLP
MSMEG_1305|M.smegmatis_MC2_155 RVASRAGVNKERIYQYFGSKQNLFSAVLEQEMIKLAAAVPLTPELAHDLG
Mflv_4072|M.gilvum_PYR-GCK HIAAAAEVGRATFFRYFSAKE---DAVVEGMAAHWLDAIADAIAAQPPEL
:. * .: :: :: *: : . :
Mb0244|M.bovis_AF2122/97 DLLRNTIVSFLRYIDANRAS-WIVMYTQATSSQAFAHTVREGREQIVQLV
Rv0238|M.tuberculosis_H37Rv DLLRNTIVSFLRYIDANRAS-WIVMYTQATSSQAFAHTVREGREQIVQLV
MUL_1163|M.ulcerans_Agy99 DLLRNAIVSFLRYIDQNQAS-WIVMYTQAVSSQAFAQTVREGREQIVELV
MLBr_02568|M.leprae_Br4923 DLLRNTIVSFLRYIDANRAS-WIVMYIQAMSLPAFAQTVREARDQITELV
TH_1911|M.thermoresistible__bu DLLRNAVRSFLTYIDTNRAS-WLVLYTQATSSQAFAHTVREGRERIIDLV
MMAR_3952|M.marinum_M EFVGDIYDLACRRPEHLRMITWANLEGLVLDPPQVEGVESVQARDVG---
MAV_0082|M.avium_104 DFVGGIYDLAREHPEHHRMISWAQLEGIALDEPHAEG-QPAFAQHVA---
Mvan_4046|M.vanbaalenii_PYR-1 EFAGDIFDLSLSHPEHFRMINWGRLEGVSLDPPAGDDGRTAPAEALD---
MAB_3705|M.abscessus_ATCC_1997 GYAGALFDHLIKHPEHLRLATWAQLERPAAGP-------AETSAYAA---
MSMEG_1305|M.smegmatis_MC2_155 EFSGRIYDYHREYPHYLRLLLWEGLDRNPLDGNPPAARDERAEHYAGDRR
Mflv_4072|M.gilvum_PYR-GCK AADAAVVAAFQDLGHGFEAVSDQVRELAVMTRSSPVFSAWTLQLYLR--Y
. .
Mb0244|M.bovis_AF2122/97 AELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMI
Rv0238|M.tuberculosis_H37Rv AELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMI
MUL_1163|M.ulcerans_Agy99 AGMLRAGTRSPRSDAEIDMMAAALVGAGEAVANRLSAGDTDVDEAAEMMI
MLBr_02568|M.leprae_Br4923 AGLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMI
TH_1911|M.thermoresistible__bu ARLLRSGTRHPEPDTDFDMMAVALVGAGEAVATRVSAGDAEVDEAAELLI
MMAR_3952|M.marinum_M VIEAAQAAGHVDPHWHPMDLLVLLFGVGLAWAQSP-----HPDAVATDRA
MAV_0082|M.avium_104 AIEAAQADGHVDGAWQPDDLLIVLFGIALAWANSP-----HPDAATNDPD
Mvan_4046|M.vanbaalenii_PYR-1 AVRAAQRDGLVDTRWDPEELLILLFGLGLAWAHWP-----DPRSVTEDAG
MAB_3705|M.abscessus_ATCC_1997 KVAAIAQTGLSAGDVEPADILALTLGLTTAWLGASPALRGLAASEPFSPE
MSMEG_1305|M.smegmatis_MC2_155 VVALAQADKTLRDDVAPAYLLYVARSMAAWWLAVP-AAIDLMLGTTVAGE
Mflv_4072|M.gilvum_PYR-GCK EAAIADLVGIRMADPAPDDPRPRLLGA------------LAMASVRIALD
.
Mb0244|M.bovis_AF2122/97 NLFWLGLKGAPVDR-LETGH-----------------
Rv0238|M.tuberculosis_H37Rv NLFWLGLKGAPVDR-LETGH-----------------
MUL_1163|M.ulcerans_Agy99 DLLWRGLKGAPSDREIGSNFAAG--------------
MLBr_02568|M.leprae_Br4923 NLFWHGLKGAPADRDFGPSIVAG--------------
TH_1911|M.thermoresistible__bu NLFWRGLKGTPAESHEDTHRENGQDVDRDGVDQSTTV
MMAR_3952|M.marinum_M VIEGRRAAAVEAARRIVAPIRGIS-------------
MAV_0082|M.avium_104 ANARRRAAAVEAARRIIAPSK----------------
Mvan_4046|M.vanbaalenii_PYR-1 QIAQRRAAAVEAASRIVAVADGAADGSDRLATSPRSR
MAB_3705|M.abscessus_ATCC_1997 RLATHRTALIAAVEALVSAAAR---------------
MSMEG_1305|M.smegmatis_MC2_155 GPDVRRKALVTLVNDAVRYRKS---------------
Mflv_4072|M.gilvum_PYR-GCK DWLVHGGSLPERVRTALASLHVA--------------