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M. avium 104 MAV_1977 (-)

annotation: TetR-family protein transcriptional regulator
coordinates: 1966739 - 1967332
length: 197

LTRRRAGEPRKGDLREAAILDAAEELLGAIGYDAMTIADIAARAGITRGALYFYFGSKQEVITALFARTV
AVLHEKSRAATEDAASGAKAIDTAMRRTEDLWREHGVVMRTAIDLAATVPQLDALWKQTADIFVVAITAI
LEHMGVPAGKGPDKSAAIAEALCWMIERNFYQASRVSPARLTRARQTCTEIWLRVAS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1977--100% (197)TetR-family protein transcriptional regulator
M. avium 104MAV_5064-6e-1229.38% (160) transcriptional regulator, TetR family protein, putative
M. avium 104MAV_0173-9e-1129.70% (202) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0080-4e-1039.42% (104) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_3103-6e-1627.75% (191) TetR family transcriptional regulator
M. tuberculosis H37RvRv0078-4e-1039.42% (104) transcriptional regulatory protein
M. leprae Br4923MLBr_01070-1e-1030.05% (203) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_0984c-4e-1131.47% (143) TetR family transcriptional regulator
M. marinum MMMAR_0224-2e-1140.38% (104) transcriptional regulatory protein
M. smegmatis MC2 155MSMEG_4022-2e-7773.47% (196) TetR-family protein transcriptional regulator
M. thermoresistible (build 8)TH_2600-5e-1527.86% (201) PUTATIVE putative transcriptional regulator, TetR family
M. ulcerans Agy99MUL_4890-1e-1038.10% (105) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_5684-2e-1232.87% (143) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MAV_1977|M.avium_104                --------------------MTRRRAGEPRKGDLREAAILDAAEELLGAI
MSMEG_4022|M.smegmatis_MC2_155      --------------------MTRRRSTAPSKGDRRREAVLDAAEALLSTT
Mflv_3103|M.gilvum_PYR-GCK          ---------------MRSPTDR----RQPQKSDLRRVAILESLNHHLRES
TH_2600|M.thermoresistible__bu      ---------------MSKPRVRNRYSSGPTRGEQRRERLLQALEDLLASR
MLBr_01070|M.leprae_Br4923          -----MIVVGNFTQSNYVPASRGRRSSQLS-GDDREQAILAVAERLLAER
Mvan_5684|M.vanbaalenii_PYR-1       MRSSTRCKVSPVTATSPTRPARGRRAARPS-GDDRELAILETAERLLADR
MAB_0984c|M.abscessus_ATCC_199      ---------------MTKPATRGRKTTRPS-GDERIQAILATAEELLGKR
Mb0080|M.bovis_AF2122/97            --------------------MEIKRRTQEERSAATREALITGARKLWGLR
Rv0078|M.tuberculosis_H37Rv         --------------------MEIKRRTQEERSAATREALITGARKLWGLR
MMAR_0224|M.marinum_M               --------------------MEIKRRTQEERSAATREALITAARKLWGSR
MUL_4890|M.ulcerans_Agy99           --------------------MESKRRTQEERSAATREALITAARKLWGSR
                                                                   .      ::   .      

MAV_1977|M.avium_104                GYDAMTIADIAARAGITRGALYFYFGSKQEVITALFARTVAVLHEKSRAA
MSMEG_4022|M.smegmatis_MC2_155      GYHAMTIADIADGAGITRGALYFYFGSKQEVITALFARCVEVLHEKSRAA
Mflv_3103|M.gilvum_PYR-GCK          GFDALNIAAVAKRAGVTRSAFYFYFENKAAAVAALLEPMY---DDGFLAS
TH_2600|M.thermoresistible__bu      PFAAIEVGDIARAAGLSRSAFYFYFPSKAAAVGAMLGDVFGEISDVLDKW
MLBr_01070|M.leprae_Br4923          PLGDFSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEAL
Mvan_5684|M.vanbaalenii_PYR-1       SLAEISVDDLAKGAGISRPTFYFYFASKDAVLLTLLERVIAEADAALAQL
MAB_0984c|M.abscessus_ATCC_199      PLADVSVDDLARGAGISRPTFYFYFSSKESVLLTLAERIIEEADANVASI
Mb0080|M.bovis_AF2122/97            GYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVEQDVMARMATL
Rv0078|M.tuberculosis_H37Rv         GYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVEQDVMARMATL
MMAR_0224|M.marinum_M               GYAEVGTPEIAAEAGVTRGAMYHQFADKAALFGEVVEAVEQDVMTRMATS
MUL_4890|M.ulcerans_Agy99           GYAEVGTPEIAAEAGVTRGAMYHQFADKAALFGEVVEAVEQDVMTRMATS
                                        .    :*  **::* ::*. * .*   .  :               

MAV_1977|M.avium_104                TED---AASGAKAIDTAMRRTEDLWREHGVVMRTAIDLAATVPQLDALWK
MSMEG_4022|M.smegmatis_MC2_155      AAD---AASGAAAIDMAMERTEALWREHGVVMRTAIDLASTVEELDRLWA
Mflv_3103|M.gilvum_PYR-GCK          DILTDTTQPPARRVRAMLEALLDTVDEHRYLLQAMLEARATSAAIRHVWD
TH_2600|M.thermoresistible__bu      TELGDSVAARRREVYDSFERVVAIWRQHAPLMAAMFDAASTDAEVRAMFE
MLBr_01070|M.leprae_Br4923          AEQ--LPADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWS
Mvan_5684|M.vanbaalenii_PYR-1       IAE--RSSDRRTIWRRGINVFFETFGAHRAVCATTVGVKSTNSEARELWS
MAB_0984c|M.abscessus_ATCC_199      DPA--AMTSPAQYWRAVIKAYFDAFGSHRALTVALSSMQGTSPELDQRWS
Mb0080|M.bovis_AF2122/97            VAAS-GAATPADAIRAAVDAWLEVSGDPEVRQLVLLDAPVVLGWAG--FR
Rv0078|M.tuberculosis_H37Rv         VAAS-GAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPVVLGWAG--FR
MMAR_0224|M.marinum_M               VAAS-GAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPAVLGWAG--FR
MUL_4890|M.ulcerans_Agy99           VTTS-GAATPADAIRAAVDAWLEVSGDPEVRQLILLDAPAVLGWAG--FC
                                                     .                      .       : 

MAV_1977|M.avium_104                QTADIFVVAITAILEHMG----VPAGKGPDKSAAIAEALCWMIERNFYQA
MSMEG_4022|M.smegmatis_MC2_155      DTADLFIDAIRAILENMG----VPAGSGVDESSSLAKTLCWMIERNFYQA
Mflv_3103|M.gilvum_PYR-GCK          EARETFVPTVAQMIASERAAGRAPDGPGPEMIAGILLEFNDRLMERHT--
TH_2600|M.thermoresistible__bu      GHIDSFVDGSAARIRHERAVGEAPDGPDPEALARVLVGMNVKALERDMRA
MLBr_01070|M.leprae_Br4923          TVMQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSD
Mvan_5684|M.vanbaalenii_PYR-1       RSMQRWIDHIAAVIEAERADGAAPVTVPARELSTALNLMNESVMTATFTG
MAB_0984c|M.abscessus_ATCC_199      EVTENWVANTTVGIEAERARGAAPSVVPARDIAIALNLINQAMMRATFTG
Mb0080|M.bovis_AF2122/97            DVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATA
Rv0078|M.tuberculosis_H37Rv         DVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATA
MMAR_0224|M.marinum_M               DVAQRYSLGMTEQLITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATA
MUL_4890|M.ulcerans_Agy99           DVAQRYSLGMTEQLITEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATA
                                       : :       :                  :                 

MAV_1977|M.avium_104                SRVSPARLTRARQTCTEIWLRVAS--------
MSMEG_4022|M.smegmatis_MC2_155      SRISNAELAKASRTCAEIWRRAARSA------
Mflv_3103|M.gilvum_PYR-GCK          -LGGRLSRDELLTAAQSVWLRTIYANDGDELQ
TH_2600|M.thermoresistible__bu      ITSGAPADADLPRVLAFVWGRVLYDA------
MLBr_01070|M.leprae_Br4923          -EKPLIPDKKVIDTLVHIWLASIYGS------
Mvan_5684|M.vanbaalenii_PYR-1       -HQPAIPDDRVLDNLVHIWTTSIYGKTD----
MAB_0984c|M.abscessus_ATCC_199      -QQPAVDDGKVVDTLLHVWLNAIYGGVCANS-
Mb0080|M.bovis_AF2122/97            -DDPKRARRETRQVLRRLIDGMLNG-------
Rv0078|M.tuberculosis_H37Rv         -DDPKRARRETRQVLRRLIDGMLNG-------
MMAR_0224|M.marinum_M               -DDPKRARRESRQVLRRLIDGMLND-------
MUL_4890|M.ulcerans_Agy99           -DDPKRARRESRQVLRRLIDGMLND-------
                                                     :