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SRWEPDARGRLERAALELYAERGFELTTVAEIAERAGLTERTFFRHYADKREVLFGGQHVLQELFVGAVA TAVGAPWASGPAVAALDAVAAGLDTVGEMFAGRHADARRRQAVVNANTALQERELIKLATLAAAIAEALR DRGIPRATAEVAGEAGIAVFKVAFARWVEVEHETDLRMVMREVLDDLRNLFVAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3469 | - | - | 100% (195) | TetR family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6862 | - | 3e-28 | 36.98% (192) | putative transcription regulator |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 1e-07 | 28.57% (133) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 3e-06 | 43.75% (48) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_0350 | - | 7e-08 | 31.21% (157) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 3e-06 | 43.75% (48) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_01733 | - | 5e-05 | 22.87% (188) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1525c | - | 2e-07 | 33.71% (89) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2812 | - | 1e-11 | 30.05% (183) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0586 | - | 9e-37 | 45.26% (190) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1899 | - | 2e-09 | 25.99% (177) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_2933 | - | 7e-12 | 29.12% (182) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1927 | - | 1e-48 | 53.93% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3860c|M.bovis_AF2122/97 ---------------------------------------------MVRPP
Rv3830c|M.tuberculosis_H37Rv ---------------------------------------------MVRPP
MMAR_2812|M.marinum_M ---------------------------------------------MTVPT
MUL_2933|M.ulcerans_Agy99 ---------------------------------------------MTVPT
MSMEG_3469|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1927|M.vanbaalenii_PYR-1 ----------------------------------------MSAAVIPGYD
MAV_0586|M.avium_104 --------------------------------------------------
Mflv_0350|M.gilvum_PYR-GCK -----------------------------------------MEGMNPEQP
TH_1899|M.thermoresistible__bu --------------------------------------------------
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
MAB_1525c|M.abscessus_ATCC_199 ------------------------------------------MSSSPSAL
Mb3860c|M.bovis_AF2122/97 --QTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHF
Rv3830c|M.tuberculosis_H37Rv --QTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHF
MMAR_2812|M.marinum_M NRHELRRRSTHEALRRAALKSFACKGFAQVTVTELAREAGVTERTFFRHF
MUL_2933|M.ulcerans_Agy99 NRHELRRRSTHEALRRAALKSFARKGFAQVTVTELAREAGVTERTFFRHF
MSMEG_3469|M.smegmatis_MC2_155 --MSRWEPDARGRLERAALELYAERGFELTTVAEIAERAGLTERTFFRHY
Mvan_1927|M.vanbaalenii_PYR-1 RRMSRWQPNARERLEQAALELYTRQGFDQTTVDDIAQRAGLTERTFFRHF
MAV_0586|M.avium_104 --MARWEPDARARLVAAALDLFNERGYDQTTVAEIAERAGLTKSTFFRHF
Mflv_0350|M.gilvum_PYR-GCK GLRERKKTRTRETVRREAFRLFELNGYAQTTVDQIAEAAFVSPRTFFRYF
TH_1899|M.thermoresistible__bu ----------------VALDLFADRGFDEVSVDDVAAAAGIGRRTLFRYY
MLBr_01733|M.leprae_Br4923 ERWREHRKKVRGEIVDAAFRALDRLG-PEVSVREIAEEAGTAKPKIYRHF
MAB_1525c|M.abscessus_ATCC_199 SRVERKKREMRQEILDSAFACFAEQGYHATGVADIAGRIGIGHGTFYRYF
*: * . . ::* .::*::
Mb3860c|M.bovis_AF2122/97 RSKHDLLFADYDAGLHWFRAALD-------ARPADESIIDSVQAAIFSFP
Rv3830c|M.tuberculosis_H37Rv RSKHDLLFADYDAGLHWFRAALD-------ARPADESIIDSVQAAIFSFP
MMAR_2812|M.marinum_M PTKEAVLFQDYENQLEWLAQALA-------QRPVSEPLFDAVLASVAAFP
MUL_2933|M.ulcerans_Agy99 PTKEAVLFQDYENQLEWLARALA-------QRPVSEPLFDAVLASVAAFP
MSMEG_3469|M.smegmatis_MC2_155 ADKREVLFGGQHVLQELFVGAVATAVGAPWASGPAVAALDAVAAGLDTVG
Mvan_1927|M.vanbaalenii_PYR-1 ADKREVLFSGQAALIDLVTASVA-------AQEDTDPPLDVVAAALTAAG
MAV_0586|M.avium_104 PDKRDVLAAGQDAIAQLLREGIA-------AAPADATPLALVCSGLKSAA
Mflv_0350|M.gilvum_PYR-GCK PTKESVLFS--DDLFNPIIEEFL-------AAPAELSPVAAYRHAAARVF
TH_1899|M.thermoresistible__bu PSKNAIPWGDFDAHLDRMRDLLD--------GIGPDVPIGAALRSMLLAF
MLBr_01733|M.leprae_Br4923 TDKSDLFEAIGIRLRDMLWAAIFP-----AIDLATDSAREIIRRSVDEYV
MAB_1525c|M.abscessus_ATCC_199 KSKRDIIEHVIDDVTGQIFEAIGAEN----AAGLADDIEQYRQQSVRIGA
* : . . .
Mb3860c|M.bovis_AF2122/97 YDVDAVTKIASLRRGELEPSRIVRHMR---EVEADFADAIQAQLRRRNCD
Rv3830c|M.tuberculosis_H37Rv YDVDAVTKIASLRRGELEPSRIVRHMR---EVEADFADAIQAQLRRRNCD
MMAR_2812|M.marinum_M HDLEVVRQAATARSELISADRIANHLR---VVQSSFAQVLTAFVRDRYAD
MUL_2933|M.ulcerans_Agy99 HDLEVVRQAATARSELISADRIANHLR---VVQSSFAQVLTAFVRNRYAD
MSMEG_3469|M.smegmatis_MC2_155 EMFAGR-HADARRRQAVVNANTALQERE-LIKLATLAAAIAEALRDRGIP
Mvan_1927|M.vanbaalenii_PYR-1 SALDGR-GDRARQRQAVIDANPGLRERE-LIKLATLADTLAEALRQRGVE
MAV_0586|M.avium_104 AAFTPFNKELAPRLRAAIAASAELQERN-ALKQIGLALAVSEALQARGVP
Mflv_0350|M.gilvum_PYR-GCK ETMAGSDYDYIIARQRLLYDLPEAKGAL-WNEHVGAIRRLTSAIAKRLGR
TH_1899|M.thermoresistible__bu NDFGEDETGRHRRRMRVILQTDALQAHS-MTMYAGWRAVVADFVARRLGL
MLBr_01733|M.leprae_Br4923 SLVDKHPNVLRVFIQGRFSAQSEATVRT-LDEGREITLTMAEMFNNELRE
MAB_1525c|M.abscessus_ATCC_199 ALAHLFRENPHLPLLLLEAGSVDSELRERVFGMLSTSDHLTEAYLRHGVE
: .
Mb3860c|M.bovis_AF2122/97 IAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELA-RVCHVALE
Rv3830c|M.tuberculosis_H37Rv IAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELA-RVCHVALE
MMAR_2812|M.marinum_M VA---NVDLVAEVAGATIAAALVVAVENWGR--NGCAVDLG-ELVAASLD
MUL_2933|M.ulcerans_Agy99 VA---NVDLVAEVAGATIAAALVVAVENWGR--YGCAEDLG-ELVAASLD
MSMEG_3469|M.smegmatis_MC2_155 RA-------TAEVAGEAGIAVFKVAFARWVE--VEHETDLR-MVMREVLD
Mvan_1927|M.vanbaalenii_PYR-1 AP-------AARLAAEVGLAVFRVAFERWVQ--SPGGAPLP-TLIAAAFA
MAV_0586|M.avium_104 EP-------AAALAAELGALAFKTAYARWAE--PDESGDLG-DMACQALR
Mflv_0350|M.gilvum_PYR-GCK PE--------DDYQARVTAGAIIGVFMAASD----DEPMSG-EAFLEALD
TH_1899|M.thermoresistible__bu AP-------SDLVPQTVAWTMLGVALSAYAYWLADESVPLA-QALADAFD
MLBr_01733|M.leprae_Br4923 MELN---RAASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLT
MAB_1525c|M.abscessus_ATCC_199 KG-----YLRADLDTEYTARAVTGMILANGLHASRGGEVQDTERFSAAVI
. .
Mb3860c|M.bovis_AF2122/97 SLRVGISDTWTTLTVSS------------------
Rv3830c|M.tuberculosis_H37Rv SLRVGISDTWTTLTVSS------------------
MMAR_2812|M.marinum_M LVRSGLAPLS-------------------------
MUL_2933|M.ulcerans_Agy99 LVRSGLAPLS-------------------------
MSMEG_3469|M.smegmatis_MC2_155 DLRNLFVAG--------------------------
Mvan_1927|M.vanbaalenii_PYR-1 DLRRIVA----------------------------
MAV_0586|M.avium_104 ELHAAAADLG-------------------------
Mflv_0350|M.gilvum_PYR-GCK LLDQALPR---------------------------
TH_1899|M.thermoresistible__bu AIRPGLDALDGKKFA--------------------
MLBr_01733|M.leprae_Br4923 IIMMAVIVGTAETLGISMNPDRPIHDAVPLDRSAS
MAB_1525c|M.abscessus_ATCC_199 ALMYGGIGP--------------------------
: