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ARWEPDARARLVAAALDLFNERGYDQTTVAEIAERAGLTKSTFFRHFPDKRDVLAAGQDAIAQLLREGIA AAPADATPLALVCSGLKSAAAAFTPFNKELAPRLRAAIAASAELQERNALKQIGLALAVSEALQARGVPE PAAALAAELGALAFKTAYARWAEPDESGDLGDMACQALRELHAAAADLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0586 | - | - | 100% (190) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2788 | - | 4e-13 | 32.24% (183) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2657 | - | 7e-13 | 29.94% (157) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3323 | - | 7e-09 | 40.58% (69) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5008 | - | 1e-10 | 34.48% (116) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3295 | - | 7e-09 | 40.58% (69) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 6e-09 | 45.10% (51) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4946 | - | 1e-08 | 50.00% (54) | putative transcriptional regulator, TetR |
| M. marinum M | MMAR_2812 | - | 7e-10 | 28.02% (182) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3469 | - | 1e-36 | 45.26% (190) | TetR family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3524 | - | 7e-14 | 32.76% (174) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2933 | - | 3e-10 | 28.02% (182) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1927 | - | 1e-35 | 42.78% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3469|M.smegmatis_MC2_155 ---------------MSRWEPDARGRLERAALELYAERGFELTTVAEIAE
Mvan_1927|M.vanbaalenii_PYR-1 ---MSAAVIPGYDRRMSRWQPNARERLEQAALELYTRQGFDQTTVDDIAQ
MAV_0586|M.avium_104 ---------------MARWEPDARARLVAAALDLFNERGYDQTTVAEIAE
MMAR_2812|M.marinum_M --------MTVPTNRHELRRRSTHEALRRAALKSFACKGFAQVTVTELAR
MUL_2933|M.ulcerans_Agy99 --------MTVPTNRHELRRRSTHEALRRAALKSFARKGFAQVTVTELAR
Mb3323|M.bovis_AF2122/97 ----------MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAE
Rv3295|M.tuberculosis_H37Rv ----------MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAE
MLBr_00717|M.leprae_Br4923 ----------MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAE
TH_3524|M.thermoresistible__bu -----------------VRGHRNREALIAAAIDLFTVNGYEQTTVEQIAE
Mflv_5008|M.gilvum_PYR-GCK ---------MTAPVRGRPRDPDADRAILQAALDLFIERGVEGSSIEQIAK
MAB_4946|M.abscessus_ATCC_1997 MEDPAEPPIRMADRQRARRSELVKEEVVEAALAEFSERGYHQTSIAHIAE
: . : . : .:*.
MSMEG_3469|M.smegmatis_MC2_155 RAGLTERTFFRHYADKREVLFGGQHVLQELFVGAVATAVGA--PWASGPA
Mvan_1927|M.vanbaalenii_PYR-1 RAGLTERTFFRHFADKREVLFSGQAALIDLVTASVA---------AQEDT
MAV_0586|M.avium_104 RAGLTKSTFFRHFPDKRDVLAAGQDAIAQLLREGIA---------AAPAD
MMAR_2812|M.marinum_M EAGVTERTFFRHFPTKEAVLFQDYENQLEWLAQALA---------QRPVS
MUL_2933|M.ulcerans_Agy99 EAGVTERTFFRHFPTKEAVLFQDYENQLEWLARALA---------QRPVS
Mb3323|M.bovis_AF2122/97 RAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNKAPAPGMTMFEEIR
Rv3295|M.tuberculosis_H37Rv RAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNKAPAPGMTMFEEIR
MLBr_00717|M.leprae_Br4923 RAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMFEEVR
TH_3524|M.thermoresistible__bu AAGVAPRTFFRHFAAKEDILFHGYADRLAEATRRFR----------AARS
Mflv_5008|M.gilvum_PYR-GCK RAGVGKPTVYRRWGTKEELIAAAMETLVAEEVGWTS-------PEAIETR
MAB_4946|M.abscessus_ATCC_1997 RLGTGHSMFYRYFTNKRDILEHVVQHATQRTIETLS--------HTLPGR
* .:: : *. .:
MSMEG_3469|M.smegmatis_MC2_155 VAALDAVAAGLDTVGEMFAGR-HADARRRQAVVNANTALQERELIKLATL
Mvan_1927|M.vanbaalenii_PYR-1 DPPLDVVAAALTAAGSALDGR-GDRARQRQAVIDANPGLRERELIKLATL
MAV_0586|M.avium_104 ATPLALVCSGLKSAAAAFTPFNKELAPRLRAAIAASAELQERNALKQIGL
MMAR_2812|M.marinum_M EPLFDAVLASVAAFPHDLEVVRQAATARSELISADRIANHLR--VVQSSF
MUL_2933|M.ulcerans_Agy99 EPLFDAVLASVAAFPHDLEVVRQAATARSELISADRIANHLR--VVQSSF
Mb3323|M.bovis_AF2122/97 TGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRI
Rv3295|M.tuberculosis_H37Rv TGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRI
MLBr_00717|M.leprae_Br4923 VGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRI
TH_3524|M.thermoresistible__bu GSLWKALAEASEAVATAIAENPGIFLVR-ARMYGELPALRATMLRINDDW
Mflv_5008|M.gilvum_PYR-GCK SPHVLVEAAIDSAAAATAAPYYRALVARVYGSAVSHPELMTVYWDRYILP
MAB_4946|M.abscessus_ATCC_1997 ITSLNEFHDFSVNLGLAYIDLVVADPRLSRLLLQQGAAVDAEMTAQFCGV
MSMEG_3469|M.smegmatis_MC2_155 AAAIAEALRDRGIPRATAEVAGEAG----IAVFKVAFARWVEVEHETD-L
Mvan_1927|M.vanbaalenii_PYR-1 ADTLAEALRQRGVEAPAARLAAEVG----LAVFRVAFERWVQSPGGAP-L
MAV_0586|M.avium_104 ALAVSEALQARGVPEPAAALAAELG----ALAFKTAYARWAEPDESGD-L
MMAR_2812|M.marinum_M AQVLTAFVRDRYADVANVDLVAEVAGATIAAALVVAVENWGRNGCAVD-L
MUL_2933|M.ulcerans_Agy99 AQVLTAFVRNRYADVANVDLVAEVAGATIAAALVVAVENWGRYGCAED-L
Mb3323|M.bovis_AF2122/97 AEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPSTDAERL
Rv3295|M.tuberculosis_H37Rv AEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPSTDAERL
MLBr_00717|M.leprae_Br4923 GDVVSVVP-ESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDADRL
TH_3524|M.thermoresistible__bu IDQMTTEVARWLGSDAAVDVRPRLAATVINGANRTAIDLWVSADGKGD-L
Mflv_5008|M.gilvum_PYR-GCK RRVQATRLLERARELGTVAADTDLDVAIDMMVGAITYRVLRPNPPDVDEM
MAB_4946|M.abscessus_ATCC_1997 FDAGAAVLGGLLRDGIESGYVREDIDVEAVADSVVGIPLGILARYGHEPN
:
MSMEG_3469|M.smegmatis_MC2_155 RMVMREVLDDLRNLFVAG-----------------
Mvan_1927|M.vanbaalenii_PYR-1 PTLIAAAFADLRRIVA-------------------
MAV_0586|M.avium_104 GDMACQALRELHAAAADLG----------------
MMAR_2812|M.marinum_M GELVAASLDLVRSGLAPLS----------------
MUL_2933|M.ulcerans_Agy99 GELVAASLDLVRSGLAPLS----------------
Mb3323|M.bovis_AF2122/97 ADACAHALLDAISRLPQIPAELADAMATARM----
Rv3295|M.tuberculosis_H37Rv ADACAHALLDAISRLPQIPAELADAMATARM----
MLBr_00717|M.leprae_Br4923 ADSCAHALLDAIARVPEISKELADAMAIARQPPQ-
TH_3524|M.thermoresistible__bu VELMADAVRLVRPTLDRIERESRTVANPVRRRDVV
Mflv_5008|M.gilvum_PYR-GCK RRYLREVYRQAGLLPPG------------------
MAB_4946|M.abscessus_ATCC_1997 QDILAARVRATADLVCRGIAP--------------