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MVAGDWLPRIPAATIGRPRIADRVVQRPGVLRRLKAAGSGDLVVMSAPAGYGKTTAAALWDFEDDRPFAW VRIDHLDDDPAHLLLHVATAVVRLTETDRTLLRYLRGPGRPALTHLVPVVVQILEDCGPLVLVLDDVHKL SAADAVTALQMLIDEAPATTTPALLGRHMLPVALARRRLQRSVVEVDQEALRLSVEEAAEVLGSVSGPHS DATVAAVVDLCEGWAAGVILTAMALRDGTALEALTRRNNLVVDYVVEEVIDRLDGDTATFLVESAVLDRF TAEQLDTVLGRDDSARMLEMLYGSGNPFLIAIDHHRVWYRYHHLFGDVLRGRLRDLAPARFRELATRAAD LLERDGDIDGALLQALDAGDRTRAAALVGREAVRLGFDGRAGVLARRLAMLDARTFAEHPDAAVARAWLG VTTADAELIHRSLMLATRSDHGQPLSDGTPSVKVAVALISSLVGAGGVNDVIRQADVVRAAGDRLVNPWW GAATVMKGAAEAMRGQVARARALLESALPVIEDLPGFQAAALAHLALLDLAAGDDDGAVARSEEARTLVD KYDLCDVVPMIVVYATSAVMAARVGDEVGARRAVAVSETLLGRLGHLSARTALLGHGLLAWTAAVIQDPE LLGRHLGAAERACHREPDAVALVQRVDRVKAMAAGGTRPLTAAELRLLPHLASHLSLQRVAEELVIGRET VKSQATAIYRKLGVSSRGEAVAEAKRVGLIAD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1633 | - | - | 100% (732) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5653 | - | 8e-09 | 26.67% (285) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_1358 | - | 2e-08 | 41.18% (85) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3107c | pknK | 2e-35 | 25.69% (759) | serine/threonine-protein kinase transcriptional regulatory |
| M. gilvum PYR-GCK | Mflv_4809 | - | 0.0 | 76.46% (718) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv3080c | pknK | 2e-35 | 25.69% (759) | serine/threonine-protein kinase transcriptional regulatory |
| M. leprae Br4923 | MLBr_01753 | - | 9e-06 | 24.17% (360) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0060 | - | 3e-05 | 31.25% (160) | nitrate/nitrite response transcriptional regulatory protein |
| M. marinum M | MMAR_2576 | pknK | 1e-35 | 26.97% (456) | serine/threonine-protein kinase transcriptional regulatory |
| M. avium 104 | MAV_0872 | - | 5e-07 | 39.77% (88) | DNA-binding response regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_4430 | - | 1e-62 | 29.01% (748) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3184 | - | 3e-09 | 43.53% (85) | PUTATIVE two component transcriptional regulator, LuxR family |
| M. ulcerans Agy99 | MUL_0351 | narL | 3e-07 | 40.28% (72) | nitrate/nitrite response regulator protein NarL |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGGFGVVYRCVQ
Rv3080c|M.tuberculosis_H37Rv MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGGFGVVYRCVQ
MMAR_2576|M.marinum_M MAEDAPYTTQAHPAQRGGISGIPGELIDAGFENVAEVGRGGFGIVYRAFQ
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 --------------------------------------------MYSLGE
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 PSLDRAVAVKVLSTDLDRDNLERFLREQRAMGRLSGHPHIVTVLQVGVLA
Rv3080c|M.tuberculosis_H37Rv PSLDRAVAVKVLSTDLDRDNLERFLREQRAMGRLSGHPHIVTVLQVGVLA
MMAR_2576|M.marinum_M PSLDRTVAVKVLTADLDPDNLDRFLREQRAMGRLSGHPHIVTILEVGTTA
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEGLAELSE
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 GGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLAGALEAAHRVGT
Rv3080c|M.tuberculosis_H37Rv GGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLAGALEAAHRVGT
MMAR_2576|M.marinum_M TGRPFLVMPYHQNDSLEALVRRNGPLDWGEVVRLGVKVAGALEAAHRVGT
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 TQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFARASDATA
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LHRDVKPGNILLTDYGEPQLTDFGIARIAGGFETATGVIAGSPAFTAPEV
Rv3080c|M.tuberculosis_H37Rv LHRDVKPGNILLTDYGEPQLTDFGIARIAGGFETATGVIAGSPAFTAPEV
MMAR_2576|M.marinum_M LHRDVKPGNILISDYGEPQLTDFGIARIAGGFQTSTGVITGSPAFTAPEV
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 CALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGLLDLACG
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LEGASPTPASDVYSLGATLFCVLTGHAAYERRSGERVIAQFLRITSQPIP
Rv3080c|M.tuberculosis_H37Rv LEGASPTPASDVYSLGATLFCALTGHAAYERRSGERVIAQFLRITSQPIP
MMAR_2576|M.marinum_M LEGAPPTPQSDVYSLGATLFSAITGHAAFERRRGEKVVAQFLRITSQPIP
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 GQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLCHRNLRR
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 DLRKQGLPADVAAAIERAMARHPADRPATAADVGEELRDVQRRNGVSVDE
Rv3080c|M.tuberculosis_H37Rv DLRKQGLPADVAAAIERAMARHPADRPATAADVGEELRDVQRRNGVSVDE
MMAR_2576|M.marinum_M NLREEGLPADVASVIEKAMARDPADRPDSAAAFGEQLRQVQREHGVAVDE
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 NLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLTLVGPGG
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------MVAGDWLPRIPAATIGRPRIADRV
Mflv_4809|M.gilvum_PYR-GCK ----------------------------------------MGRPRIADRV
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 MPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRPSVPTGSL
Rv3080c|M.tuberculosis_H37Rv MPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRPSVPTGSL
MMAR_2576|M.marinum_M MAHPVELGAPRSDLATARSTYGHD---THATPAPPTPATKYRPQVPARSR
MSMEG_4430|M.smegmatis_MC2_155 -----------------MDASEGPAAGHGDTERAVLLATKLHIPAIAGQL
MLBr_01753|M.leprae_Br4923 VGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDNLRRCIGD
Mvan_1633|M.vanbaalenii_PYR-1 VQRPGVLRRLKAAGSGDLVVMSAPAGYGKTTAAALWDFEDDR---PFAWV
Mflv_4809|M.gilvum_PYR-GCK VPRPDLLKRLESSAGGDLVVLTAPAGYGKTTVTAMWDAEDRR---QFAWA
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 VTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRDGAAVAWL
Rv3080c|M.tuberculosis_H37Rv VTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRDGAAVAWL
MMAR_2576|M.marinum_M VSRRRLTDALSAAGRRRLILIYAPSGYGKSTLAAQWREELVRAGVAVAWL
MSMEG_4430|M.smegmatis_MC2_155 VHRTALLDALSQSCRSRLILLSAPVGWGKTTLLSQWALGAGKD-QRFGWL
MLBr_01753|M.leprae_Br4923 RRMLMVLDNCEYLLDVCANVMTTLLGACPSLTILATSREPIGVAGEVIWR
Mvan_1633|M.vanbaalenii_PYR-1 RIDHLDDDPAHLLLHVATAVVRLT-ETDRTLLRYLRGPGRPALTHLVPVV
Mflv_4809|M.gilvum_PYR-GCK RIDHLDDDPGHLLLHIATAVVRLG-AGDDHLLNYLRGPGR-EPEHLLPAV
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 TIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGDDAGRYVLTSL
Rv3080c|M.tuberculosis_H37Rv TIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGDDAGRYVLTSL
MMAR_2576|M.marinum_M TIDDDDNNPVWFLAHLLESIRRVHPGVAESLDHVLEEHGDDGSRYLLTSI
MSMEG_4430|M.smegmatis_MC2_155 SLDASDNDPVWFWMYVIAALQKISPGVGTRAVELLT-MGADPIQVVLPTL
MLBr_01753|M.leprae_Br4923 VSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLDGMPLAIE
Mvan_1633|M.vanbaalenii_PYR-1 VQILEDCG-PLVLVLDDVHKLSAADAVTALQMLIDEAPATTTPALLGRHM
Mflv_4809|M.gilvum_PYR-GCK VRLLEEFG-PIVVILDDVHKLSTPQSISALHAFVDAAPLTTTVALLGRFL
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 IDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQLIVTSWSR
Rv3080c|M.tuberculosis_H37Rv IDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQLIVTSWSR
MMAR_2576|M.marinum_M IDALHDADEPTTLIVDDWQRVSDSQTIAALSFLLEHGCHHLQIIVTSWSR
MSMEG_4430|M.smegmatis_MC2_155 LNDLDAVARPIVLILDDYHMVVNRAIHEQVAFAVGRMPANLHVVLATRSD
MLBr_01753|M.leprae_Br4923 LAAARIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALL
Mvan_1633|M.vanbaalenii_PYR-1 LPVALARRRLQRSVVEVDQEALRLSV--EEAAEVLGSVSGPHSD-ATVAA
Mflv_4809|M.gilvum_PYR-GCK LPLDIARRRLAGNLVEVDQDALRLTA--EETVAALESVRGPSDD-ATVAT
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 AGLPVGRLRIGDELAEIDSAALRFDT--DEAAALLNDAGGLRLPRADVQA
Rv3080c|M.tuberculosis_H37Rv AGLPVGRLRIGDELAEIDSAALRFDT--DEAAALLNDAGGLRLPRADVQA
MMAR_2576|M.marinum_M TGLPLSRLRLADELVEIDSAALRFDS--GEATSFFDSLGGLSLTGNDVAA
MSMEG_4430|M.smegmatis_MC2_155 PLLPLARLRANGELVEMRSDDLRFGV--GEAGQLLNDVLGLDLTEEDVRL
MLBr_01753|M.leprae_Br4923 TESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRLTMLIDKSLV
Mvan_1633|M.vanbaalenii_PYR-1 VVDLCEGWAAGVILTAMALRDG----TALEALTRRNNLVVDYVVEEVIDR
Mflv_4809|M.gilvum_PYR-GCK VIDLCEGWAAGVILTAMALRDG----TAPEALAGRNNLVVEYVVEEVIDR
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEFLSENVLDT
Rv3080c|M.tuberculosis_H37Rv LTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEFLSENVLDT
MMAR_2576|M.marinum_M LTESTDGWAAGLQLAGLSVRGGADASTLVGKLCGTSEVIGEFLAENVLAS
MSMEG_4430|M.smegmatis_MC2_155 LHRRTEGWAAGLYLAALSLAGRAQAAAFIRTFAGDNRHIVDYLMAEVLDR
MLBr_01753|M.leprae_Br4923 IVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLD
Mvan_1633|M.vanbaalenii_PYR-1 LDGDTATFLVESAVLDRFT--------AEQLDTVLGRDDSARMLEMLYGS
Mflv_4809|M.gilvum_PYR-GCK VDDDTRSFLLESAMLDRFT--------AEHLDAVLGRVDAAWMLEQLATS
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LEPELREFLLVASVTERTC--------GGLASALAGITNGRAMLEEAEHR
Rv3080c|M.tuberculosis_H37Rv LEPELREFLLVASVTERTC--------GGLASALAGITNGRAMLEEAEHR
MMAR_2576|M.marinum_M LEPEIVDFVLATSIPERIC--------ADLASALAQVPRGQALLEQVAQR
MSMEG_4430|M.smegmatis_MC2_155 QSPRIRNFLLRTSVMRRFN--------GALCDAVLQSSDSVSVLEEMERE
MLBr_01753|M.leprae_Br4923 TPGDIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFG
Mvan_1633|M.vanbaalenii_PYR-1 GNPFLIAIDHHRVWYRYHHLFGDVLRGRLRDLAPARFRELATRAADLLER
Mflv_4809|M.gilvum_PYR-GCK GNPFLISLDSQGDSFRYHHLFGDVLRARLRASEPARFRELASRAADLLER
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 G-LFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAE
Rv3080c|M.tuberculosis_H37Rv G-LFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAE
MMAR_2576|M.marinum_M G-LFLQPVDGEPGWFHYHQMFAEFLRRRLERDDPQRVAQLHRTAALWLKE
MSMEG_4430|M.smegmatis_MC2_155 N-LFLVPLDMSRHWYRYHHLFGELLRAELHRCEPELVPGLHRRAAKWFEA
MLBr_01753|M.leprae_Br4923 RGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAILASSPPD
Mvan_1633|M.vanbaalenii_PYR-1 DGDIDGALLQALDAGDRTRAAALVGREAVRLGFDGRAGVLARRLAMLDAR
Mflv_4809|M.gilvum_PYR-GCK EGDIDGALVHALEAGDRARAAALVGREAVRLGFDGRAGVLARRLGMLDAR
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 NGYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTS
Rv3080c|M.tuberculosis_H37Rv NGYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTS
MMAR_2576|M.marinum_M HDRLHDAVKHALAAGDPALAVDFVEDDETNLLEQSKMTTLLEIVKKLPPR
MSMEG_4430|M.smegmatis_MC2_155 EGLVDEALRHLVAAGDIAESADLIVEDWANELAGGGLSTVSGWLDLLPEG
MLBr_01753|M.leprae_Br4923 GSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARPYFAEAV
Mvan_1633|M.vanbaalenii_PYR-1 TFAEHP--DAAVARAWL----GVTTADAELIHRSLMLATRSDHGQPLSDG
Mflv_4809|M.gilvum_PYR-GCK TFAEQP--DAAVARAWL----GVTTADAELIQRSLMLALHSDHGGPLADG
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 -----------------------MDVTKTEKVRVVVGDDHPLFREGVVRA
MAB_0060|M.abscessus_ATCC_1997 -----------------------MQVSG-ELVRVVVGDDHPLFREGVVRA
TH_3184|M.thermoresistible__bu ----------------------MEPVAAPSPVRIVLVDDHEMVIEGLKAM
Mb3107c|M.bovis_AF2122/97 MVVSRA--RLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQAD
Rv3080c|M.tuberculosis_H37Rv MVVSRA--RLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQAD
MMAR_2576|M.marinum_M LIVSRE--RLQLAIAWANILLQRKVPADAALNLFTKALDHADP--ATQAD
MSMEG_4430|M.smegmatis_MC2_155 TVRGDP--RLSAIRAWVALNVGLFDDARIWIEAVAAGLEGVSAAEGSARA
MLBr_01753|M.leprae_Br4923 ELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAADDLAQEIGDRF
Mvan_1633|M.vanbaalenii_PYR-1 TPSVKVAVALISSLVGA--GGVNDVIRQADVVRAAGDRLVNPWWGAATVM
Mflv_4809|M.gilvum_PYR-GCK TPSVSVAVALISSLVGV--GGVAEVIRHADTVRAAGDNLVNPWWGAATVM
MAV_0872|M.avium_104 -------MNVVGEAEDG--SAALELIKSHQPDVALLDYRMPGMDGAQVAA
MUL_0351|M.ulcerans_Agy99 LSLSGS-VNVVGEADDG--AAALELIETHLPDVALLDYRMPRMDGAQVAA
MAB_0060|M.abscessus_ATCC_1997 LTASGQ-ITVVAEAENG--TGALELIREHRPDVALVDYRMPELDGTQVAA
TH_3184|M.thermoresistible__bu LAAFEDRVCVVGHAVGA--ERAVEVVAELDPDIVLCDVRMQNTSGLDLCL
Mb3107c|M.bovis_AF2122/97 LRAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAAL
Rv3080c|M.tuberculosis_H37Rv LRAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAAL
MMAR_2576|M.marinum_M LRVEADVLQAVADTFADRIDRVDTLVAEALSRPQTFHPRVPAVAGNVSAF
MSMEG_4430|M.smegmatis_MC2_155 G--LSEQLVALREVYAFKIGDVTNALDAARQAATLEVGEAPPARSAAHVT
MLBr_01753|M.leprae_Br4923 VSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQT
: : . .
Mvan_1633|M.vanbaalenii_PYR-1 KGAAE-AMRGQVARARALLESALPVIEDLP--GFQAAALAHLALLDLAAG
Mflv_4809|M.gilvum_PYR-GCK KGAAE-AMRGQGGRARLLLESALPVIEDLP--GFHAAALAHLALLDLAAG
MAV_0872|M.avium_104 AVRAD-GLATR--------------VLLIS--AHDESAIVYQALQQGAAG
MUL_0351|M.ulcerans_Agy99 AVRSN-GLPTR--------------VLLIS--AHDESAIVYQALQQGAAG
MAB_0060|M.abscessus_ATCC_1997 AVRRD-ELPTR--------------VLLLS--AHDDAAIVYRALEEGAAG
TH_3184|M.thermoresistible__bu TLREQ-APHRK--------------VVMLS--VYDDEQYLYQALRVGASG
Mb3107c|M.bovis_AF2122/97 AAICR-FEFAEVYPLLDWAAPYQEMMGPFG--TVYAQCLRGMAARNRLDI
Rv3080c|M.tuberculosis_H37Rv AAICR-FEFAEVYPLLDWAAPYQEMMGPFG--TVYAQCLRGMAARNRLDI
MMAR_2576|M.marinum_M AALYR-FQFDQVRRLLAWATPYREMMGPFV--SVYARCYLGLAAKFALDI
MSMEG_4430|M.smegmatis_MC2_155 YGAAL-YFSGDIDEARTELQRAVELTERTGDRRHRVYALGYLALIEAESG
MLBr_01753|M.leprae_Br4923 RALVHRDVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAA
*
Mvan_1633|M.vanbaalenii_PYR-1 DDDGAVARSEEAR---TLVDKYDLCDVVPMIVVYATSAVMAARVGDEVGA
Mflv_4809|M.gilvum_PYR-GCK DDEAAVERCDAAR---TLADKYDLSDVVPMIVVYSTSAVMSARVGDVPAA
MAV_0872|M.avium_104 --------------------------------------------------
MUL_0351|M.ulcerans_Agy99 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 VAALQNFRTAFEV---GTAVGAHSHAARLAGSLLAELLYETGDLAGAGRL
Rv3080c|M.tuberculosis_H37Rv VAALQNFRTAFEV---GTAVGAHSHAARLAGSLLAELLYETGDLAGAGRL
MMAR_2576|M.marinum_M ATALAEFRRAVEI---AQSCGTNSNATRIAGAFLGEMLHDVGELTEAKLL
MSMEG_4430|M.smegmatis_MC2_155 QLADAEHLIRRATGVGPDPAGTQNFIDVAVSLAVSVVLYASGEWAAAADA
MLBr_01753|M.leprae_Br4923 VEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRLADNSVSATT
Mvan_1633|M.vanbaalenii_PYR-1 RRAVAVSETLLGRLGHLSARTALLGHGLLAWTAA----------------
Mflv_4809|M.gilvum_PYR-GCK LHAVQITQTLLERLGNLSARTALLGHGLLAWTAA----------------
MAV_0872|M.avium_104 ------------FVLKDSTRSEIVKAVLDCAQGR----------------
MUL_0351|M.ulcerans_Agy99 ------------FLLKDSTRTEIVKAVLDCAKGR----------------
MAB_0060|M.abscessus_ATCC_1997 ------------FLSKESTRTELVGAVLDCARGR----------------
TH_3184|M.thermoresistible__bu ------------YLLKSISSDELVRQLEMVHRGQ----------------
Mb3107c|M.bovis_AF2122/97 MDESYLLGSEGGAVDYLAAR-YVIGARVKAAQGD----------------
Rv3080c|M.tuberculosis_H37Rv MDESYLLGSEGGAVDYLAAR-YVIGARVKAAQGD----------------
MMAR_2576|M.marinum_M LDESYRLGPEGGGVDYLVAR-FVAGARVNAAHGD----------------
MSMEG_4430|M.smegmatis_MC2_155 AHLAVGLARKGAGILEVAKALMVRAKILNDFGDL----------------
MLBr_01753|M.leprae_Br4923 GWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGISDSMEL
: :
Mvan_1633|M.vanbaalenii_PYR-1 -----VIQDPELLGRHLGAAERACHREPDAVALVQRVDRVKAMAAGGTRP
Mflv_4809|M.gilvum_PYR-GCK -----ALQDRALLSRHLTAAERVRHREPDAVALVQRVERVKAMAVGGTRP
MAV_0872|M.avium_104 -----DVVAPALVG-GLAAEIRQRAEP---------------TGP----V
MUL_0351|M.ulcerans_Agy99 -----DVVAPSLVG-GLAGEIRQRAAP---------------MAP----V
MAB_0060|M.abscessus_ATCC_1997 -----DVVAASLTA-GLAGEIRKRAQP---------------AGP----S
TH_3184|M.thermoresistible__bu -----TALDPGMAARAVDTAARLQRDE---------------FWPGARHG
Mb3107c|M.bovis_AF2122/97 -----HEGAADRLSTGGDTAVQLGLPRLAARINNERIRLGIALPAAVAAD
Rv3080c|M.tuberculosis_H37Rv -----HEGAADRLSTGGDTAVQLGLPRLAARINNERIRLGIALPAAVAAD
MMAR_2576|M.marinum_M -----CAAAAERLEAGMAVADQLHLPRLSAAINHERVRLGIGLSPSVSAR
MSMEG_4430|M.smegmatis_MC2_155 -----EAAEKSRSEAGALLRRCPDNVAVHPMIGSAGQGRRVAVAAYNDEH
MLBr_01753|M.leprae_Br4923 LAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGA
Mvan_1633|M.vanbaalenii_PYR-1 LTAA-----------------------------------------ELRLL
Mflv_4809|M.gilvum_PYR-GCK LTAA-----------------------------------------ELRLL
MAV_0872|M.avium_104 LSAR-----------------------------------------EREVL
MUL_0351|M.ulcerans_Agy99 LSAR-----------------------------------------EREVL
MAB_0060|M.abscessus_ATCC_1997 LSTR-----------------------------------------EREVL
TH_3184|M.thermoresistible__bu LTQR-----------------------------------------ESEIL
Mb3107c|M.bovis_AF2122/97 LLAPRTIPRDNG------------------------IATMTAELDEDSAV
Rv3080c|M.tuberculosis_H37Rv LLAPRTIPRDNG------------------------IATMTAELDEDSAV
MMAR_2576|M.marinum_M LRDTRHNSSDDG------------------------IVTLTYELDEASAI
MSMEG_4430|M.smegmatis_MC2_155 IAEDLTS-------------------------------------KELEVL
MLBr_01753|M.leprae_Br4923 MGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVI
: * :
Mvan_1633|M.vanbaalenii_PYR-1 PHLASHLS------LQRVAEELVIGRETVKSQATAIYRKLGVSS------
Mflv_4809|M.gilvum_PYR-GCK PHLATHLS------LQRIAEELVIGRETAKSQATSIYRKLGVSS------
MAV_0872|M.avium_104 HRIARGQS------IPAIAGELYVAPSTVKTHVQRLYEKLGVSD------
MUL_0351|M.ulcerans_Agy99 HRIAKGQS------IPAIAGELYVAPSTVKTHVQRLYEKLGVSD------
MAB_0060|M.abscessus_ATCC_1997 RMIAAGQT------VPAIARALFLAPSTVKTHVQRLYEKLGVGD------
TH_3184|M.thermoresistible__bu SYVVNGLS------NRGIAAKLVIGDETVKSHLRSIYRKLGVSD------
Mb3107c|M.bovis_AF2122/97 RLLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATG
Rv3080c|M.tuberculosis_H37Rv RLLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATG
MMAR_2576|M.marinum_M RLLSAGGSEQDRADAHRRARDLLTGIDATLRPWAALRAQLLLAETLRAAG
MSMEG_4430|M.smegmatis_MC2_155 RLLATRLS------RRDIGQRLYVSLNTVKTHQRAIYRKLGVDN------
MLBr_01753|M.leprae_Br4923 RLVSEGLD------TKDIAARLFVSVRTVHTHLTRIYSKLGLTS------
: . * . . : :: .
Mvan_1633|M.vanbaalenii_PYR-1 --------RGEAVAEAKRVGLIAD-------
Mflv_4809|M.gilvum_PYR-GCK --------RGQAVSEAIRIGLLAD-------
MAV_0872|M.avium_104 --------RAAAVAEAMRQGLLS--------
MUL_0351|M.ulcerans_Agy99 --------RAAAVAEAMRQGLLD--------
MAB_0060|M.abscessus_ATCC_1997 --------RAAAVAEAMRRGLLE--------
TH_3184|M.thermoresistible__bu --------RAAAVATALREGIYQ--------
Mb3107c|M.bovis_AF2122/97 RESDARNELAPVATKCAELGLSRLLVDAGLA
Rv3080c|M.tuberculosis_H37Rv RESDARNELAPVATKCAELGLSRLLVDAGLA
MMAR_2576|M.marinum_M LQPDP--ESAGLAQRCNELGLVRLAVDAGLT
MSMEG_4430|M.smegmatis_MC2_155 --------RNSAVARGRELGLL---------
MLBr_01753|M.leprae_Br4923 --------RVQLVQEAARHN-----------
. . .