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MTDVDPHATRRDLVPNIPAELLEAGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDNLERFL REQRAMGRLSGHPHIVTVLQVGVLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLAGALEAA HRVGTLHRDVKPGNILLTDYGEPQLTDFGIARIAGGFETATGVIAGSPAFTAPEVLEGASPTPASDVYSL GATLFCVLTGHAAYERRSGERVIAQFLRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGE ELRDVQRRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRPSVPTGSLVTRSR LTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRP TLAESLGHVLEEHGDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQLIV TSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLRLPRADVQALTTSTDGWAAALRLAAL SLRGGGDATQLLRGLSGASDVIHEFLSENVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAMLE EAEHRGLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAENGYLHEAVDHALAAGD PARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSMVVSRARLQLAIAWANILLQRPAPATGALNRFETAL GRAELPEATQADLRAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAICRFEF AEVYPLLDWAAPYQEMMGPFGTVYAQCLRGMAARNRLDIVAALQNFRTAFEVGTAVGAHSHAARLAGSLL AELLYETGDLAGAGRLMDESYLLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLP RLAARINNERIRLGIALPAAVAADLLAPRTIPRDNGIATMTAELDEDSAVRLLSAGDSADRDQACQRAGA LAAAIDGTRRPLAALQAQILHIETLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3107c | pknK | - | 100% (1110) | serine/threonine-protein kinase transcriptional regulatory protein |
| M. bovis AF2122 / 97 | Mb2198 | pknL | 1e-35 | 34.62% (286) | transmembrane serine/threonine-protein kinase L |
| M. bovis AF2122 / 97 | Mb0014c | pknB | 8e-34 | 35.29% (306) | transmembrane serine/threonine-protein kinase B PKNB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5210 | - | 3e-37 | 35.60% (323) | protein kinase |
| M. tuberculosis H37Rv | Rv3080c | pknK | 0.0 | 99.91% (1110) | serine/threonine-protein kinase transcriptional regulatory |
| M. leprae Br4923 | MLBr_00897 | - | 1e-35 | 33.44% (299) | serine-threonine protein kinase |
| M. abscessus ATCC 19977 | MAB_1988c | - | 2e-35 | 36.26% (273) | serine/threonine protein kinase |
| M. marinum M | MMAR_2576 | pknK | 0.0 | 65.13% (1104) | serine/threonine-protein kinase transcriptional regulatory |
| M. avium 104 | MAV_2318 | - | 1e-38 | 35.05% (331) | serine-threonine protein kinase |
| M. smegmatis MC2 155 | MSMEG_0529 | - | 0.0 | 52.84% (1109) | serine/threonine-protein kinase PknK |
| M. thermoresistible (build 8) | TH_2610 | - | 1e-35 | 33.66% (306) | PUTATIVE serine/threonine protein kinase |
| M. ulcerans Agy99 | MUL_4753 | pknK_3 | 4e-88 | 38.38% (555) | serine/threonine-protein kinase transcriptional regulatory |
| M. vanbaalenii PYR-1 | Mvan_1076 | - | 2e-92 | 52.87% (331) | protein kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3107c|M.bovis_AF2122/97 -------MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGGFG
Rv3080c|M.tuberculosis_H37Rv -------MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGGFG
MMAR_2576|M.marinum_M -------MAEDAPYTTQAHPAQRGGISGIPGELIDAGFENVAEVGRGGFG
MSMEG_0529|M.smegmatis_MC2_155 -------MVRNDP-----LPTQRDLPAGIPAELVAAGFEDPDEIGRGGFG
MLBr_00897|M.leprae_Br4923 --------------------------------MLDGRYLLKAKIGNGGTA
MAV_2318|M.avium_104 MAQAESPGSSSGRPGPHRRQAQAESPGSFAGTLLDGRYLIESKIASGGTS
MAB_1988c|M.abscessus_ATCC_199 ---MTSPKSPTGRLDP------------MIGAVLDGRYRIEAPIATGGMS
TH_2610|M.thermoresistible__bu -------VETYQQSDP------------FAGTVLDGRYRIDTLIATGGMS
Mflv_5210|M.gilvum_PYR-GCK ---------------------MSTPQGGARLGTRFGPYELHSVIGVGGMG
MUL_4753|M.ulcerans_Agy99 ----------------------------------MDGFADAAEVGRGGFG
Mvan_1076|M.vanbaalenii_PYR-1 ------------------------MAGEIAYELAAAGFVDAVEVGRGGGG
: :. ** .
Mb3107c|M.bovis_AF2122/97 VVYRCVQPSLDRAVAVKVLSTDLDRDN--LERFLREQRAMGRLSGHPHIV
Rv3080c|M.tuberculosis_H37Rv VVYRCVQPSLDRAVAVKVLSTDLDRDN--LERFLREQRAMGRLSGHPHIV
MMAR_2576|M.marinum_M IVYRAFQPSLDRTVAVKVLTADLDPDN--LDRFLREQRAMGRLSGHPHIV
MSMEG_0529|M.smegmatis_MC2_155 VVYRCVQRALDRTVAVKVLTTDLEPDN--LERFMREQVAMGKLSGHPNIV
MLBr_00897|M.leprae_Br4923 TVYRGVDIRLDRPVAVKVMDSRYTGDEQLLTRFQLEARSVARLK-DPGLV
MAV_2318|M.avium_104 TVYRGVDTRLDRPVAVKVMDPRYAGDEQFLTRFQREARAVARLK-DPGLV
MAB_1988c|M.abscessus_ATCC_199 TVYRGLDTRLDRPVAVKVMDSRYASDSGFLARFRLEARAVARLR-HPGLV
TH_2610|M.thermoresistible__bu AVYRGLDLRLDRPVAVKVMDSRYAGDQQFLTRFQREARAAARLK-DPGLV
Mflv_5210|M.gilvum_PYR-GCK EVYRAYDTARERMVAIKLLRPEMAADHSFQERFRRESRVAARLQ-EPHVI
MUL_4753|M.ulcerans_Agy99 VVYRCRQVDLDRVVAIKVLTIDLDENR---PRFEREQRAMAKLTGHPNIV
Mvan_1076|M.vanbaalenii_PYR-1 VVYRCHQQSLGRTVAIKVLASSLDEDD--RERFLREGYAMGGLSGHPNIV
*** : * **:*:: : ** * . * .* ::
Mb3107c|M.bovis_AF2122/97 TVLQVG--VLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLA
Rv3080c|M.tuberculosis_H37Rv TVLQVG--VLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLA
MMAR_2576|M.marinum_M TILEVG--TTATGRPFLVMPYHQNDSLEALVRRNGPLDWGEVVRLGVKVA
MSMEG_0529|M.smegmatis_MC2_155 NIFQVG--TIASGRPYIVMQYHPHGSLSAKIQAAGPLGWRGALRIGVKMA
MLBr_00897|M.leprae_Br4923 AVYDQG--IDARHP-FLVMELIEGGTLRELLAERGPMPPHAVVAVLRPVL
MAV_2318|M.avium_104 AVYDQG--LDARHP-FLVMELIEGGTLRELLGERGPMPPYAVAAVLRPVL
MAB_1988c|M.abscessus_ATCC_199 AVFDQG--MDGRHP-FLVMELIDGGTLRELLRERGPMPPHAVAAVFNPLL
TH_2610|M.thermoresistible__bu AVYDQGPGSPASHPPYLVMELIEGGTLRELLRERGPMPPHAAAAVLAPVL
Mflv_5210|M.gilvum_PYR-GCK PVHNFG---EIDGVLYIDMRLVEGASLKEVLRSDGPLQPARAVSIIRQVA
MUL_4753|M.ulcerans_Agy99 SVLQIG--ETRDGHPYLVMPYCRRGSVQTEISRLGRLSLADILQLGVALA
Mvan_1076|M.vanbaalenii_PYR-1 NILQVG--MTEQDRPFIVMPYHARGSLADQVRREGRIPWPDALRIGVKLC
: : * :: * :: : * : : :
Mb3107c|M.bovis_AF2122/97 GALEAAHRVGTLHRDVKPGNILLTDYGEPQLTDFGIAR-IAGGFETATGV
Rv3080c|M.tuberculosis_H37Rv GALEAAHRVGTLHRDVKPGNILLTDYGEPQLTDFGIAR-IAGGFETATGV
MMAR_2576|M.marinum_M GALEAAHRVGTLHRDVKPGNILISDYGEPQLTDFGIAR-IAGGFQTSTGV
MSMEG_0529|M.smegmatis_MC2_155 GALETAHQRDTLHRDVKPANILLTEYGEPQLTDFGIAR-IAGGFETAEGA
MLBr_00897|M.leprae_Br4923 GGLAAAHRAGLVHRDVKPENILISDDGDVKIADFGLVRAVAAAGITSTSV
MAV_2318|M.avium_104 GGLAAAHRAGLVHRDVKPENVLISDDGEVKIADFGLVRAVAAAGITSASV
MAB_1988c|M.abscessus_ATCC_199 GGLAVAHRSGLVHRDVKPENVLISDDGEVKLADFGLVRAVAEAGITSTSV
TH_2610|M.thermoresistible__bu GGLAVAHRAGLVHRDIKPENVLISDDGEVKIADFGLVRAVAEAKITSDSV
Mflv_5210|M.gilvum_PYR-GCK AALDDAHANGLVHRDIKPENVLLTGDDFAYLVDFGIAHGGGEASVTSTGL
MUL_4753|M.ulcerans_Agy99 AGLESAHRLDILHRDIKPANVLLTDFGEPALTDFGLAH-MAGGFRTATGL
Mvan_1076|M.vanbaalenii_PYR-1 GALETAHRTGTLHRDIKPANVLVNDYGDPQLSDFGTAR-IVGGYKTVTGF
..* ** . :***:** *:*:. . : *** .: . * .
Mb3107c|M.bovis_AF2122/97 IAGSPAFTAPEVLEGASPTPASDVYSLGATLFCVLTGHAAYERRSGERVI
Rv3080c|M.tuberculosis_H37Rv IAGSPAFTAPEVLEGASPTPASDVYSLGATLFCALTGHAAYERRSGERVI
MMAR_2576|M.marinum_M ITGSPAFTAPEVLEGAPPTPQSDVYSLGATLFSAITGHAAFERRRGEKVV
MSMEG_0529|M.smegmatis_MC2_155 IMGSPAYTAPEVLLGESPTVASDVYSLASTVFTASTGHAVFERGKGEQMV
MLBr_00897|M.leprae_Br4923 ILGTVAYLSPEQVRDGDASPRSDVYSAGIMTYELLTGHTPFTGDSALSIA
MAV_2318|M.avium_104 ILGTAAYLSPEQVRDGAATPRSDVYAAGILAYELLTGRTPFTGDSTLAIA
MAB_1988c|M.abscessus_ATCC_199 ILGTAAYLSPEQVRTGSAGPRSDVYSAGILMYELLTGSTPFTGDTPLALA
TH_2610|M.thermoresistible__bu ILGTAAYLSPEQVATGDATPRSDVYAVGILTYEMLTGNTPFTGDNALALA
Mflv_5210|M.gilvum_PYR-GCK VVGSSAYMAPERFSGERGGPASDIYSLACLLYESLTGRAPFEAADVRQVW
MUL_4753|M.ulcerans_Agy99 FTASPAFTASELARGGEPDRASDVYGVGATLFCALTGHPPFERRKGESVI
Mvan_1076|M.vanbaalenii_PYR-1 FTGTLSYTAPEVLTGKPPTVEADVYSLGATLYAMIAGKAAHERNTDEELI
. .: :: :.* :*:*. . : :* . . :
Mb3107c|M.bovis_AF2122/97 AQFLRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGEELR
Rv3080c|M.tuberculosis_H37Rv AQFLRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGEELR
MMAR_2576|M.marinum_M AQFLRITSQPIPNLREEGLPADVASVIEKAMARDPADRPDSAAAFGEQLR
MSMEG_0529|M.smegmatis_MC2_155 AQFLRITRHPAPNLRDADLPADLSAAIEQAMSRTISDRPESAQAFGEQLR
MLBr_00897|M.leprae_Br4923 YQRLEID-VPRASTVITGVPQQFDELVARATVRDPSGRYADAIEMAAQVD
MAV_2318|M.avium_104 YRRLDAD-VPPPSAAIDGVPAQFDDFVQRATARDPADRYADAVEMGADLD
MAB_1988c|M.abscessus_ATCC_199 YQRIDRD-VQAPSEAIDGVPEEFDELVLRATSRDPDARYADAAQFGAELD
TH_2610|M.thermoresistible__bu YQRLDND-VPPPSSAISGVPPQFDELVATATARDPADRFADAHDMAAAVA
Mflv_5210|M.gilvum_PYR-GCK SAHMFAA-PPRPSIMRRGVSRAFDDVIARGMAKNPTERYATAGELARAAA
MUL_4753|M.ulcerans_Agy99 AQILRVANDPVPDLAEYDVAEDVASVVNRALSRDPAARP-TMVELGEAIQ
Mvan_1076|M.vanbaalenii_PYR-1 AHYLRITSQPVPDLRHLGIPSDVCSAIEKAMSLESAARFDSAAEFGRALQ
: .. .:. . : . * ..
Mb3107c|M.bovis_AF2122/97 DVQRRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPA
Rv3080c|M.tuberculosis_H37Rv DVQRRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPA
MMAR_2576|M.marinum_M QVQREHGVAVDEMAHPVELGAPRSDLATARSTYGHD---THATPAPPTPA
MSMEG_0529|M.smegmatis_MC2_155 ELQRRHGLPVDDMPIPIAPPTDR---PSSIASPTPSSGYPVRTLTPPAPA
MLBr_00897|M.leprae_Br4923 SIAEELALPPFRVPAPRNT-------------------------------
MAV_2318|M.avium_104 AIADELALPGFRVPAPRNS-------------------------------
MAB_1988c|M.abscessus_ATCC_199 AISSELRLPPFRVPAPRDS-------------------------------
TH_2610|M.thermoresistible__bu DLVAELELPPFRVPAPRNS-------------------------------
Mflv_5210|M.gilvum_PYR-GCK AAASAAPVAEPVPPVTPPS------------------------------T
MUL_4753|M.ulcerans_Agy99 SLQAAHGQAVDAMALEGGKRSTSVS-------------SESAWHVSARQT
Mvan_1076|M.vanbaalenii_PYR-1 EAQRHNGLTADTMAIGEPTPAAAPP-----------------------EG
. .
Mb3107c|M.bovis_AF2122/97 TKYRPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWRE
Rv3080c|M.tuberculosis_H37Rv TKYRPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWRE
MMAR_2576|M.marinum_M TKYRPQVPARSRVSRRRLTDALSAAGRRRLILIYAPSGYGKSTLAAQWRE
MSMEG_0529|M.smegmatis_MC2_155 TRFQMPSSAKRLVERARLIDVLRAQRDKKLTVIHGPTGFGKSTLAVQWAK
MLBr_00897|M.leprae_Br4923 AQYRSAALHRGHMVE-------RPVEQQVQPVVNAPMPHSTRQFTRRL--
MAV_2318|M.avium_104 ALHRSAALHR--------------EAGRRAPGAEPPARHPTRHLTRGP--
MAB_1988c|M.abscessus_ATCC_199 KQHVAEQLYRSRLIDSGGNTTGNLSAPGQADAADAASAAAALGVSARP--
TH_2610|M.thermoresistible__bu AQHLSAIRQHS-------------QSARPTTTLQPPXXXGAGGRARVA--
Mflv_5210|M.gilvum_PYR-GCK RQFSGVHPAMTPPPAPAPIAAARRPGRGQGALVAGIVVMFVAAAVLALVL
MUL_4753|M.ulcerans_Agy99 RGNLPAKLAGFVGRQAELAELGALISTSRPVTLTGVGGVGKTSLAVQAAG
Mvan_1076|M.vanbaalenii_PYR-1 TQALPLSVPSDSVVLPPIPAAAPPASPPAPPPPPPPDMFARSPSNSPPIT
Mb3107c|M.bovis_AF2122/97 ELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEH
Rv3080c|M.tuberculosis_H37Rv ELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEH
MMAR_2576|M.marinum_M ELVRAGVAVAWLTIDDDDNNPVWFLAHLLESIRRVHPGVAESLDHVLEEH
MSMEG_0529|M.smegmatis_MC2_155 QLAADGVAVAWLTVDDDDNNVVWFLSHVIEAIRSVMPALASDLGDVLEEH
MLBr_00897|M.leprae_Br4923 ----------------------------RDCSAPRRP------ARPDIDS
MAV_2318|M.avium_104 ----------------------------EEWPQPEPP------AHVGAEP
MAB_1988c|M.abscessus_ATCC_199 ----------------------------STPPRPRVPNPTRMMDPVPAYD
TH_2610|M.thermoresistible__bu ----------------------------TEIG-----------DRIGIVD
Mflv_5210|M.gilvum_PYR-GCK VFTGG-----------------------SDPQPPRIAAPPSSSSDTSTPP
MUL_4753|M.ulcerans_Agy99 EHVSHFHDG----------------VWLVDIGELSDGALLAGLAARMLGI
Mvan_1076|M.vanbaalenii_PYR-1 PWPVAPPPYP-----------------ASVAPAKNRKKTLIALAAAAAAV
Mb3107c|M.bovis_AF2122/97 GDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGC
Rv3080c|M.tuberculosis_H37Rv GDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGC
MMAR_2576|M.marinum_M GDDGSRYLLTSIIDALHDADEPTTLIVDDWQRVSDSQTIAALSFLLEHGC
MSMEG_0529|M.smegmatis_MC2_155 GDDAERYVLTSLINDIHSSGRRMTLVIDDWHRVTDPATIAALRYLLDNVA
MLBr_00897|M.leprae_Br4923 ---PEEYEYEP-VPDRFAG-----IAISEFIWARQHARRMVLIWVGVVVA
MAV_2318|M.avium_104 DDDEDDYEYQS-VTGEFAG-----IPISEFVWARQHNRRMVLVWLALVLA
MAB_1988c|M.abscessus_ATCC_199 AGYDEEFDGEPDESAFFAD-----IDDSDYRYERQQSRRAIFIWLVIVLI
TH_2610|M.thermoresistible__bu --------QPPTARGRHAN-----AVRTAFRNDE----------------
Mflv_5210|M.gilvum_PYR-GCK STSAVEGVSGTDSQGFVGHTARCDSGDTPAALIRTSLSLAIICDRGDGDY
MUL_4753|M.ulcerans_Agy99 RDQGARPLTEVLTDALAERDALVIFDGCEHVIDHAAQLIDTLLQGCPQLH
Mvan_1076|M.vanbaalenii_PYR-1 LLVIGTVVIVASRDNRSGEAGGVTTAARPTAEAQPGWRPIADSRIPLAAA
Mb3107c|M.bovis_AF2122/97 HHLQLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGG
Rv3080c|M.tuberculosis_H37Rv HHLQLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGG
MMAR_2576|M.marinum_M HHLQIIVTSWSRTGLPLSRLRLADELVEIDSAALRFDSGEATSFFDSLGG
MSMEG_0529|M.smegmatis_MC2_155 SGLTVVVTSRTQSGLPMSRMRMQGEIVEIDATALRFDVSESGSFLVDLAG
MLBr_00897|M.leprae_Br4923 IAGLVATVAWTIGSHLSGLL------------------------------
MAV_2318|M.avium_104 VTGMVATAAWTIGRNLNGLF------------------------------
MAB_1988c|M.abscessus_ATCC_199 LTSSVAAGCWSLGANITNLL------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK YYRGERLRDGANREIDGARR-SGDGFTVTGSDGARYDVQPDQLTISSGGS
MUL_4753|M.ulcerans_Agy99 ILATSRELLGIGGEAVLALSPLPYPDAASVSSRSSVARYDAVALFVERAR
Mvan_1076|M.vanbaalenii_PYR-1 AATEADGTIWIFGGMGADNRVSGAHEGYDPAIDSWKGGEALPVPVQRAMS
Mb3107c|M.bovis_AF2122/97 LRLPRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIH
Rv3080c|M.tuberculosis_H37Rv LRLPRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIH
MMAR_2576|M.marinum_M LSLTGNDVAALTESTDGWAAGLQLAGLSVRGGADASTLVGKLCGTSEVIG
MSMEG_0529|M.smegmatis_MC2_155 LDLDQTDVEELTEKTDGWVAALQLASLTLRDRDDPVQLIETMTGRHHVIS
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK VDSAEPALEYGSAQ------------------------------------
MUL_4753|M.ulcerans_Agy99 TARPGFTLTQRNAAAVARICERLDGLPLAIELAAARLRAVSVEQIADRLS
Mvan_1076|M.vanbaalenii_PYR-1 VTWQDTPVVLGGWRSEGADTKVATDQVWRVVNSRWVQLPPLLQPRAAAAA
Mb3107c|M.bovis_AF2122/97 EFLSENVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAMLEEAE
Rv3080c|M.tuberculosis_H37Rv EFLSENVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAMLEEAE
MMAR_2576|M.marinum_M EFLAENVLASLEPEIVDFVLATSIPERICADLASALAQVPRGQALLEQVA
MSMEG_0529|M.smegmatis_MC2_155 EFLAENVLETLEPSTLDFLLATSIPERICGGLASALTDVPDGQAILEKIE
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 DRFGLLTRGQRGAPTRQQTLSYCIDWSYDHCTPIQQQLWARLSVFAGSFD
Mvan_1076|M.vanbaalenii_PYR-1 AVVGDRIVVTGGVDAAGKVLDTTEVYDGSGWTQAAPMPTPRQLLAAASDG
Mb3107c|M.bovis_AF2122/97 HRGLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFA
Rv3080c|M.tuberculosis_H37Rv HRGLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFA
MMAR_2576|M.marinum_M QRGLFLQPVDGEPGWFHYHQMFAEFLRRRLERDDPQRVAQLHRTAALWLK
MSMEG_0529|M.smegmatis_MC2_155 ERDLFLRRIDDQ--WFRYHQLFRDFLRHRLSR---ERVCDLHRRACRWYA
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 LDAAQYVAPQDMDADDLLDELCALVDKSILIRTEDDGAVRFRLLSTMREY
Mvan_1076|M.vanbaalenii_PYR-1 ELVYAIGGTNGTADLATVEAYDPAADTWTAMPALPEPRSDFG--------
Mb3107c|M.bovis_AF2122/97 ENGYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPT
Rv3080c|M.tuberculosis_H37Rv ENGYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPT
MMAR_2576|M.marinum_M EHDRLHDAVKHALAAGDPALAVDFVEDDETNLLEQSKMTTLLEIVKKLPP
MSMEG_0529|M.smegmatis_MC2_155 GQRLVREAVDHALAAGDETEAVRLVENDGLYLVSGGQMATLIGLTAKLPQ
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 GNSRIDAEQYQGLQQSHFDWCERLVTQAHLEWFSRKQVDWIHRLRSELPN
Mvan_1076|M.vanbaalenii_PYR-1 --VAVTDARLVAVGGTAAGRPLKTVTALDLTTSTWSDLPDLGTARRGAAV
Mb3107c|M.bovis_AF2122/97 SMVVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQADL
Rv3080c|M.tuberculosis_H37Rv SMVVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQADL
MMAR_2576|M.marinum_M RLIVSRERLQLAIAWANILLQRKVPADAALNLFTKALDHADP--ATQADL
MSMEG_0529|M.smegmatis_MC2_155 DIVRSNPRLQLALAWANIVLHRVPAARDALARVEATMADAGLSEDEIADM
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 IEEALQFGLEKAPESVLLMAAKLRNLFVVSGKLQVGRLWVERALSTTTSA
Mvan_1076|M.vanbaalenii_PYR-1 AAVGKSVYVIGGSTGAGDGQATSSAEALKLAPRTPQPAAQWRSLPDAPTA
Mb3107c|M.bovis_AF2122/97 RAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALA
Rv3080c|M.tuberculosis_H37Rv RAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALA
MMAR_2576|M.marinum_M RVEADVLQAVADTFADRIDRVDTLVAEALSRPQTFHPRVPAVAGNVSAFA
MSMEG_0529|M.smegmatis_MC2_155 RAEADVVRAIADLRSDRLSGIDEHVAACLQRRDRMPPFSVATAATVATFA
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 QPSGARIAALAALAMFAVLQTDWPTAQSCVAQAHEHGAAVPDPIAESLLG
Mvan_1076|M.vanbaalenii_PYR-1 RLMMAYTVLDDQIWIAGGIREGETLDTVETYDTRTQQWQSQPSLPIPLNH
Mb3107c|M.bovis_AF2122/97 AICRFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAA
Rv3080c|M.tuberculosis_H37Rv AICRFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAA
MMAR_2576|M.marinum_M ALYRFQFDQVRRLLAWATPYREMMG-PFVSVYARCYLGLAAKFALDIATA
MSMEG_0529|M.smegmatis_MC2_155 AAYRYDLDEVERIQTWAAPYYERSGDAFSIVNGLCFCGIAHHLMLNNAVA
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 VARGLGALLQGQVEQVQTDAEQGLAAGDFELQVLGMWLMPLRHLAVGDPE
Mvan_1076|M.vanbaalenii_PYR-1 AVAATYRGEVVVIGGATDTITQASDKVFAFRDGTWVELASLQHARAAPAA
Mb3107c|M.bovis_AF2122/97 LQNFRTAFEVGTAVG-AHSHAARLAGSLLAELLYETGDLAGAGRLMDESY
Rv3080c|M.tuberculosis_H37Rv LQNFRTAFEVGTAVG-AHSHAARLAGSLLAELLYETGDLAGAGRLMDESY
MMAR_2576|M.marinum_M LAEFRRAVEIAQSCG-TNSNATRIAGAFLGEMLHDVGELTEAKLLLDESY
MSMEG_0529|M.smegmatis_MC2_155 EQTLRRALRIAKRSGGIHSYAGRLASSLLGEILYEKGDLAEAERLLDEGY
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 PALRWAEKAHSVSESRVEVQMRTYSLSALAVSHLMLGDTGSAERSLREGL
Mvan_1076|M.vanbaalenii_PYR-1 AVVDDKLVVVGGQNDKQVVPQTEVFDGQSWTQAADMPTPREHLAAVSDGV
Mb3107c|M.bovis_AF2122/97 LLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPR
Rv3080c|M.tuberculosis_H37Rv LLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPR
MMAR_2576|M.marinum_M RLGPEGGGVDYLVARFVAGARVNAAHGDCAAAAERLEAGMAVADQLHLPR
MSMEG_0529|M.smegmatis_MC2_155 KLGPEGGSVDFKIARYVISARIKALQGDRLGAAQRLDEATRVARSLSLNR
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 KLCQVIDDPWSGASYLEGLAWTAGANGNLRRAVVLMAAAAALSRSSGAG-
Mvan_1076|M.vanbaalenii_PYR-1 YVYTVGGRLLSADENLAAFERFDPESGNWEKLPDMPTPRGSYGAAYLDGR
Mb3107c|M.bovis_AF2122/97 LAARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATMTAELDEDSA
Rv3080c|M.tuberculosis_H37Rv LAARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATMTAELDEDSA
MMAR_2576|M.marinum_M LSAAINHERVRLGIGLSPSVSARLRDTRHNSSD--DGIVTLTYELDEASA
MSMEG_0529|M.smegmatis_MC2_155 LQALAEHERIRLGLPPHPEFGPMPVVSYDARREPVDAMDAIALQFEEASA
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 ------STVIALVGSMHQQCERAAREELSDAVFETARVEGESLSFDDAAD
Mvan_1076|M.vanbaalenii_PYR-1 IVVVGGEEPTRVLPTVEIYDIANRKWSTQAPVNTPVHGQAVAAVGSTVYC
Mb3107c|M.bovis_AF2122/97 VRLLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAAT
Rv3080c|M.tuberculosis_H37Rv VRLLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAAT
MMAR_2576|M.marinum_M IRLLSAGGSEQDRADAHRRARDLLTGIDATLRPWAALRAQLLLAETLRAA
MSMEG_0529|M.smegmatis_MC2_155 IRRLMASDDPAARDLACRWAREWVDRLSALNRPQALLRARRLLGACLAAD
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 VALTEP--------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 IGGADRPTHEGPVATVEALDFT----------------------------
Mb3107c|M.bovis_AF2122/97 GRESDARNELAPVATKCAELGLSRLLVDAGLA------------------
Rv3080c|M.tuberculosis_H37Rv GRESDARNELAPVATKCAELGLSRLLVDAGLA------------------
MMAR_2576|M.marinum_M GLQPDP--ESAGLAQRCNELGLVRLAVDAGLT------------------
MSMEG_0529|M.smegmatis_MC2_155 GRTAEAKAMVATVAAQCAQLRMLRYLVDGGPQVVATLVELRADQEAGRWS
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 -----------------------
Rv3080c|M.tuberculosis_H37Rv -----------------------
MMAR_2576|M.marinum_M -----------------------
MSMEG_0529|M.smegmatis_MC2_155 PEWPEVPADFLQDAINSVAPQRY
MLBr_00897|M.leprae_Br4923 -----------------------
MAV_2318|M.avium_104 -----------------------
MAB_1988c|M.abscessus_ATCC_199 -----------------------
TH_2610|M.thermoresistible__bu -----------------------
Mflv_5210|M.gilvum_PYR-GCK -----------------------
MUL_4753|M.ulcerans_Agy99 -----------------------
Mvan_1076|M.vanbaalenii_PYR-1 -----------------------