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GRPRIADRVVPRPDLLKRLESSAGGDLVVLTAPAGYGKTTVTAMWDAEDRRQFAWARIDHLDDDPGHLLL HIATAVVRLGAGDDHLLNYLRGPGREPEHLLPAVVRLLEEFGPIVVILDDVHKLSTPQSISALHAFVDAA PLTTTVALLGRFLLPLDIARRRLAGNLVEVDQDALRLTAEETVAALESVRGPSDDATVATVIDLCEGWAA GVILTAMALRDGTAPEALAGRNNLVVEYVVEEVIDRVDDDTRSFLLESAMLDRFTAEHLDAVLGRVDAAW MLEQLATSGNPFLISLDSQGDSFRYHHLFGDVLRARLRASEPARFRELASRAADLLEREGDIDGALVHAL EAGDRARAAALVGREAVRLGFDGRAGVLARRLGMLDARTFAEQPDAAVARAWLGVTTADAELIQRSLMLA LHSDHGGPLADGTPSVSVAVALISSLVGVGGVAEVIRHADTVRAAGDNLVNPWWGAATVMKGAAEAMRGQ GGRARLLLESALPVIEDLPGFHAAALAHLALLDLAAGDDEAAVERCDAARTLADKYDLSDVVPMIVVYST SAVMSARVGDVPAALHAVQITQTLLERLGNLSARTALLGHGLLAWTAAALQDRALLSRHLTAAERVRHRE PDAVALVQRVERVKAMAVGGTRPLTAAELRLLPHLATHLSLQRIAEELVIGRETAKSQATSIYRKLGVSS RGQAVSEAIRIGLLAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4809 | - | - | 100% (717) | regulatory protein, LuxR |
| M. gilvum PYR-GCK | Mflv_5014 | - | 5e-08 | 46.15% (65) | two component LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1156 | - | 9e-07 | 24.41% (553) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3107c | pknK | 2e-34 | 25.27% (744) | serine/threonine-protein kinase transcriptional regulatory |
| M. tuberculosis H37Rv | Rv3080c | pknK | 2e-34 | 25.27% (744) | serine/threonine-protein kinase transcriptional regulatory |
| M. leprae Br4923 | MLBr_01753 | - | 3e-05 | 24.47% (282) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0060 | - | 7e-05 | 31.91% (141) | nitrate/nitrite response transcriptional regulatory protein |
| M. marinum M | MMAR_2576 | pknK | 1e-37 | 28.71% (418) | serine/threonine-protein kinase transcriptional regulatory |
| M. avium 104 | MAV_0872 | - | 1e-06 | 43.55% (62) | DNA-binding response regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_4430 | - | 2e-63 | 30.85% (752) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3184 | - | 2e-09 | 44.71% (85) | PUTATIVE two component transcriptional regulator, LuxR family |
| M. ulcerans Agy99 | MUL_2876 | - | 7e-07 | 34.55% (110) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1633 | - | 0.0 | 76.46% (718) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ---------MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGG
Rv3080c|M.tuberculosis_H37Rv ---------MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGG
MMAR_2576|M.marinum_M ---------MAEDAPYTTQAHPAQRGGISGIPGELIDAGFENVAEVGRGG
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 FGVVYRCVQPSLDRAVAVKVLSTDLDRDNLERFLREQRAMGRLSGHPHIV
Rv3080c|M.tuberculosis_H37Rv FGVVYRCVQPSLDRAVAVKVLSTDLDRDNLERFLREQRAMGRLSGHPHIV
MMAR_2576|M.marinum_M FGIVYRAFQPSLDRTVAVKVLTADLDPDNLDRFLREQRAMGRLSGHPHIV
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 TVLQVGVLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLAGA
Rv3080c|M.tuberculosis_H37Rv TVLQVGVLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLAGA
MMAR_2576|M.marinum_M TILEVGTTATGRPFLVMPYHQNDSLEALVRRNGPLDWGEVVRLGVKVAGA
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LEAAHRVGTLHRDVKPGNILLTDYGEPQLTDFGIARIAGGFETATGVIAG
Rv3080c|M.tuberculosis_H37Rv LEAAHRVGTLHRDVKPGNILLTDYGEPQLTDFGIARIAGGFETATGVIAG
MMAR_2576|M.marinum_M LEAAHRVGTLHRDVKPGNILISDYGEPQLTDFGIARIAGGFQTSTGVITG
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 SPAFTAPEVLEGASPTPASDVYSLGATLFCVLTGHAAYERRSGERVIAQF
Rv3080c|M.tuberculosis_H37Rv SPAFTAPEVLEGASPTPASDVYSLGATLFCALTGHAAYERRSGERVIAQF
MMAR_2576|M.marinum_M SPAFTAPEVLEGAPPTPQSDVYSLGATLFSAITGHAAFERRRGEKVVAQF
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1633|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGEELRDVQ
Rv3080c|M.tuberculosis_H37Rv LRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGEELRDVQ
MMAR_2576|M.marinum_M LRITSQPIPNLREEGLPADVASVIEKAMARDPADRPDSAAAFGEQLRQVQ
MSMEG_4430|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDNL
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK -------------------------------------------------M
Mvan_1633|M.vanbaalenii_PYR-1 -----------------------------------MVAGDWLPRIPAATI
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 RRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKY
Rv3080c|M.tuberculosis_H37Rv RRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKY
MMAR_2576|M.marinum_M REHGVAVDEMAHPVELGAPRSDLATARSTYGHD---THATPAPPTPATKY
MSMEG_4430|M.smegmatis_MC2_155 --------------------------MDASEGPAAGHGDTERAVLLATKL
MLBr_01753|M.leprae_Br4923 RRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPSLTILATSREPIGVA
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK GRPRIADRVVPRPDLLKRLESSAGGDLVVLTAPAGYGKTTVTAMWD----
Mvan_1633|M.vanbaalenii_PYR-1 GRPRIADRVVQRPGVLRRLKAAGSGDLVVMSAPAGYGKTTAAALWD----
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 RPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWR----
Rv3080c|M.tuberculosis_H37Rv RPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWR----
MMAR_2576|M.marinum_M RPQVPARSRVSRRRLTDALSAAGRRRLILIYAPSGYGKSTLAAQWR----
MSMEG_4430|M.smegmatis_MC2_155 HIPAIAGQLVHRTALLDALSQSCRSRLILLSAPVGWGKTTLLSQWA----
MLBr_01753|M.leprae_Br4923 GEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLDG
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK ----AEDRR---QFAWARIDHLDDDPGHLLLHIATAVVRLG-AGDDHLLN
Mvan_1633|M.vanbaalenii_PYR-1 ----FEDDR---PFAWVRIDHLDDDPAHLLLHVATAVVRLT-ETDRTLLR
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ----EELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGH
Rv3080c|M.tuberculosis_H37Rv ----EELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGH
MMAR_2576|M.marinum_M ----EELVRAGVAVAWLTIDDDDNNPVWFLAHLLESIRRVHPGVAESLDH
MSMEG_4430|M.smegmatis_MC2_155 ----LGAGKD-QRFGWLSLDASDNDPVWFWMYVIAALQKISPGVGTRAVE
MLBr_01753|M.leprae_Br4923 MPLAIELAAARIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASMD
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK YLRGPGR-EPEHLLPAVVRLLEEFG-PIVVILDDVHKLSTPQSISALHAF
Mvan_1633|M.vanbaalenii_PYR-1 YLRGPGRPALTHLVPVVVQILEDCG-PLVLVLDDVHKLSAADAVTALQML
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 VLEEHGDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFL
Rv3080c|M.tuberculosis_H37Rv VLEEHGDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFL
MMAR_2576|M.marinum_M VLEEHGDDGSRYLLTSIIDALHDADEPTTLIVDDWQRVSDSQTIAALSFL
MSMEG_4430|M.smegmatis_MC2_155 LLT-MGADPIQVVLPTLLNDLDAVARPIVLILDDYHMVVNRAIHEQVAFA
MLBr_01753|M.leprae_Br4923 WSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRLTML
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK VDAAPLTTTVALLGRFLLPLDIARRRLAGNLVEVDQDALRLT--------
Mvan_1633|M.vanbaalenii_PYR-1 IDEAPATTTPALLGRHMLPVALARRRLQRSVVEVDQEALRLS--------
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LDNGCHHLQLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFD--------
Rv3080c|M.tuberculosis_H37Rv LDNGCHHLQLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFD--------
MMAR_2576|M.marinum_M LEHGCHHLQIIVTSWSRTGLPLSRLRLADELVEIDSAALRFD--------
MSMEG_4430|M.smegmatis_MC2_155 VGRMPANLHVVLATRSDPLLPLARLRANGELVEMRSDDLRFG--------
MLBr_01753|M.leprae_Br4923 IDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMA
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK ----AEETVAALESVRGPSDD-ATVATVIDLCEGWAAGVILTAMALRDG-
Mvan_1633|M.vanbaalenii_PYR-1 ----VEEAAEVLGSVSGPHSD-ATVAAVVDLCEGWAAGVILTAMALRDG-
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ----TDEAAALLNDAGGLRLPRADVQALTTSTDGWAAALRLAALSLRGGG
Rv3080c|M.tuberculosis_H37Rv ----TDEAAALLNDAGGLRLPRADVQALTTSTDGWAAALRLAALSLRGGG
MMAR_2576|M.marinum_M ----SGEATSFFDSLGGLSLTGNDVAALTESTDGWAAGLQLAGLSVRGGA
MSMEG_4430|M.smegmatis_MC2_155 ----VGEAGQLLNDVLGLDLTEEDVRLLHRRTEGWAAGLYLAALSLAGRA
MLBr_01753|M.leprae_Br4923 LGALLDTPGDIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSL
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK ---TAPEALAGRNNLVVEYVVEEVIDRVDDDTRSFLLESAMLDRFTAEHL
Mvan_1633|M.vanbaalenii_PYR-1 ---TALEALTRRNNLVVDYVVEEVIDRLDGDTATFLVESAVLDRFTAEQL
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 DATQLLRGLSGASDVIHEFLSENVLDTLEPELREFLLVASVTERTCGGLA
Rv3080c|M.tuberculosis_H37Rv DATQLLRGLSGASDVIHEFLSENVLDTLEPELREFLLVASVTERTCGGLA
MMAR_2576|M.marinum_M DASTLVGKLCGTSEVIGEFLAENVLASLEPEIVDFVLATSIPERICADLA
MSMEG_4430|M.smegmatis_MC2_155 QAAAFIRTFAGDNRHIVDYLMAEVLDRQSPRIRNFLLRTSVMRRFNGALC
MLBr_01753|M.leprae_Br4923 QPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAIL
MUL_2876|M.ulcerans_Agy99 --------------------------------MGFSPRRAIPERTVGGVI
Mflv_4809|M.gilvum_PYR-GCK DAVLGRVDAAWMLEQLATSGNPFLISLDSQGDSFRYHHLFGDVLRARLRA
Mvan_1633|M.vanbaalenii_PYR-1 DTVLGRDDSARMLEMLYGSGNPFLIAIDHHRVWYRYHHLFGDVLRGRLRD
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 SALAGITNGRAMLEEAEHRG-LFLQRTEDDPNWFRFHQMFADFLHRRLER
Rv3080c|M.tuberculosis_H37Rv SALAGITNGRAMLEEAEHRG-LFLQRTEDDPNWFRFHQMFADFLHRRLER
MMAR_2576|M.marinum_M SALAQVPRGQALLEQVAQRG-LFLQPVDGEPGWFHYHQMFAEFLRRRLER
MSMEG_4430|M.smegmatis_MC2_155 DAVLQSSDSVSVLEEMEREN-LFLVPLDMSRHWYRYHHLFGELLRAELHR
MLBr_01753|M.leprae_Br4923 ASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARP
MUL_2876|M.ulcerans_Agy99 DVVDMPDPPAFPTLADDEHPGWASRPIRESDATRHYREAFGDCN------
Mflv_4809|M.gilvum_PYR-GCK SEPARFRELASRAADLLEREGDIDGALVHALEAGDRARAAALVGREAVRL
Mvan_1633|M.vanbaalenii_PYR-1 LAPARFRELATRAADLLERDGDIDGALLQALDAGDRTRAAALVGREAVRL
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 GGSHRVAELHRRASAWFAENGYLHEAVDHALAAGDPARAVDLVEQDETNL
Rv3080c|M.tuberculosis_H37Rv GGSHRVAELHRRASAWFAENGYLHEAVDHALAAGDPARAVDLVEQDETNL
MMAR_2576|M.marinum_M DDPQRVAQLHRTAALWLKEHDRLHDAVKHALAAGDPALAVDFVEDDETNL
MSMEG_4430|M.smegmatis_MC2_155 CEPELVPGLHRRAAKWFEAEGLVDEALRHLVAAGDIAESADLIVEDWANE
MLBr_01753|M.leprae_Br4923 YFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAADDLAQ
MUL_2876|M.ulcerans_Agy99 ----------------VDPTDDPMAVVAEAIDVNAAAVRHALESQGDVHA
Mflv_4809|M.gilvum_PYR-GCK GFDGRAGVLARRLGMLDARTFAEQPDAAVARAWL----GVTTADAELIQR
Mvan_1633|M.vanbaalenii_PYR-1 GFDGRAGVLARRLAMLDARTFAEHPDAAVARAWL----GVTTADAELIHR
MAB_0060|M.abscessus_ATCC_1997 -----------------------------------------MQVSGELVR
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu ---------------------------------------MEPVAAPSPVR
Mb3107c|M.bovis_AF2122/97 PEQSKMTTLLAIVQKLPTSMVVSRARLQLAIAWANILLQRPAPATGALNR
Rv3080c|M.tuberculosis_H37Rv PEQSKMTTLLAIVQKLPTSMVVSRARLQLAIAWANILLQRPAPATGALNR
MMAR_2576|M.marinum_M LEQSKMTTLLEIVKKLPPRLIVSRERLQLAIAWANILLQRKVPADAALNL
MSMEG_4430|M.smegmatis_MC2_155 LAGGGLSTVSGWLDLLPEGTVRGDPRLSAIRAWVALN--VGLFDDARIWI
MLBr_01753|M.leprae_Br4923 EIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTF
MUL_2876|M.ulcerans_Agy99 VNALETLLDLSSLEREMIEDGAARRTLALLQVQEALSKLRAVDDVAMIVD
Mflv_4809|M.gilvum_PYR-GCK SLMLALHSDHGGPLADGTPSVSVAVALISSLVGV--GGVAEVIRHADTVR
Mvan_1633|M.vanbaalenii_PYR-1 SLMLATRSDHGQPLSDGTPSVKVAVALISSLVGA--GGVNDVIRQADVVR
MAB_0060|M.abscessus_ATCC_1997 VVVGDDHPLFREGVVRALTASG-QITVVAEAENG--TGALELIREHRPDV
MAV_0872|M.avium_104 ------------------------MNVVGEAEDG--SAALELIKSHQPDV
TH_3184|M.thermoresistible__bu IVLVDDHEMVIEGLKAMLAAFEDRVCVVGHAVGA--ERAVEVVAELDPDI
Mb3107c|M.bovis_AF2122/97 FETALGRAELPEATQADLRAEADVLRAVAEVFADRVERVDDLLAEAMSRP
Rv3080c|M.tuberculosis_H37Rv FETALGRAELPEATQADLRAEADVLRAVAEVFADRVERVDDLLAEAMSRP
MMAR_2576|M.marinum_M FTKALDHADP--ATQADLRVEADVLQAVADTFADRIDRVDTLVAEALSRP
MSMEG_4430|M.smegmatis_MC2_155 EAVAAGLEGVSAAEGSARAGLSEQLVALREVYAFKIGDVTNALDAARQAA
MLBr_01753|M.leprae_Br4923 GLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAM
MUL_2876|M.ulcerans_Agy99 RAPRELVESCGFDRAVLFRVHEGRLVMESAYFGEDREGAEKMVAFAQSVA
: :
Mflv_4809|M.gilvum_PYR-GCK AAGDNLVNPWWGAATVMKGAA-----------------EAMRGQGGRARL
Mvan_1633|M.vanbaalenii_PYR-1 AAGDRLVNPWWGAATVMKGAA-----------------EAMRGQVARARA
MAB_0060|M.abscessus_ATCC_1997 ALVDYRMPELDGTQVAAAVRR-----------------DELPTR------
MAV_0872|M.avium_104 ALLDYRMPGMDGAQVAAAVRA-----------------DGLATR------
TH_3184|M.thermoresistible__bu VLCDVRMQNTSGLDLCLTLRE-----------------QAPHRK------
Mb3107c|M.bovis_AF2122/97 DTLPPRVPGTAGNTAALAAICRFEFAEVYPLLDWAAPYQEMMGPFGTVYA
Rv3080c|M.tuberculosis_H37Rv DTLPPRVPGTAGNTAALAAICRFEFAEVYPLLDWAAPYQEMMGPFGTVYA
MMAR_2576|M.marinum_M QTFHPRVPAVAGNVSAFAALYRFQFDQVRRLLAWATPYREMMGPFVSVYA
MSMEG_4430|M.smegmatis_MC2_155 TLEVGEAPPARSAAHVTYGAALYFSG----------DIDEARTELQRAVE
MLBr_01753|M.leprae_Br4923 GDVAAAVEASEACRPHLGADHG------LVAIHLELMAAVALARGDVIVA
MUL_2876|M.ulcerans_Agy99 PLLDHMLIETQMIRRHAPAIVR-------------DARNDPRVNRPIVDF
Mflv_4809|M.gilvum_PYR-GCK LLESALPVIEDLPGFHAAALAHLALLDLAAGDDEAAVERCD---------
Mvan_1633|M.vanbaalenii_PYR-1 LLESALPVIEDLPGFQAAALAHLALLDLAAGDDDGAVARSE---------
MAB_0060|M.abscessus_ATCC_1997 --------VLLLSAHDDAAIVYRALEEGAAG-------------------
MAV_0872|M.avium_104 --------VLLISAHDESAIVYQALQQGAAG-------------------
TH_3184|M.thermoresistible__bu --------VVMLSVYDDEQYLYQALRVGASG-------------------
Mb3107c|M.bovis_AF2122/97 QCLRGMAARNRLDIVAALQNFRTAFEVGTAVGAHSHAARLAGSLLAELLY
Rv3080c|M.tuberculosis_H37Rv QCLRGMAARNRLDIVAALQNFRTAFEVGTAVGAHSHAARLAGSLLAELLY
MMAR_2576|M.marinum_M RCYLGLAAKFALDIATALAEFRRAVEIAQSCGTNSNATRIAGAFLGEMLH
MSMEG_4430|M.smegmatis_MC2_155 LTERTGDRRHRVYALGYLALIEAESGQLADAEHLIRRATGVGP-------
MLBr_01753|M.leprae_Br4923 RRLADNSVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACG---
MUL_2876|M.ulcerans_Agy99 SLTHSYVAAPVMPTGKMIGFLHADRLYSGRIVDEIDRDTVWAFAEG----
Mflv_4809|M.gilvum_PYR-GCK -------------AARTLADKYDLSDVVPMIVVYSTSAVMSARVGDVPAA
Mvan_1633|M.vanbaalenii_PYR-1 -------------EARTLVDKYDLCDVVPMIVVYATSAVMAARVGDEVGA
MAB_0060|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0872|M.avium_104 --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ETGDLAGAGRLMDESYLLGSEGGAVDYLAARYVIGARVKAAQGDHEGAAD
Rv3080c|M.tuberculosis_H37Rv ETGDLAGAGRLMDESYLLGSEGGAVDYLAARYVIGARVKAAQGDHEGAAD
MMAR_2576|M.marinum_M DVGELTEAKLLLDESYRLGPEGGGVDYLVARFVAGARVNAAHGDCAAAAE
MSMEG_4430|M.smegmatis_MC2_155 -------------DPAGTQNFIDVAVSLAVSVVLYASGEWAAAADAAHLA
MLBr_01753|M.leprae_Br4923 ------------ADIQASLGISDSMELLAELISQGDNHRQAGRLFGAASA
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK LHAVQITQTLLERLGNLSARTALLGHGLLAWTAAALQDRALLSRHLTAAE
Mvan_1633|M.vanbaalenii_PYR-1 RRAVAVSETLLGRLGHLSARTALLGHGLLAWTAAVIQDPELLGRHLGAAE
MAB_0060|M.abscessus_ATCC_1997 ------------FLSKESTRTELVGAVLDCARGRDVVAASLTAGLAGEIR
MAV_0872|M.avium_104 ------------FVLKDSTRSEIVKAVLDCAQGRDVVAPALVGGLAAEIR
TH_3184|M.thermoresistible__bu ------------YLLKSISSDELVRQLEMVHRGQTALDPGMAARAVDTAA
Mb3107c|M.bovis_AF2122/97 RLSTGGDTAVQLGLPRLAARINNERIRLGIALPAAVAADLLAPRTIPRDN
Rv3080c|M.tuberculosis_H37Rv RLSTGGDTAVQLGLPRLAARINNERIRLGIALPAAVAADLLAPRTIPRDN
MMAR_2576|M.marinum_M RLEAGMAVADQLHLPRLSAAINHERVRLGIGLSPSVSARLRDTRHNSSDD
MSMEG_4430|M.smegmatis_MC2_155 VGLARKGAGILEVAKALMVRAKILNDFGDLEAAEKSRSEAGALLRRCPDN
MLBr_01753|M.leprae_Br4923 QREKTGEVRFKVWDAGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAIT
MUL_2876|M.ulcerans_Agy99 ------------FGYAYERTVLLERMRRQHAEVRSALASADEAARALQDA
Mflv_4809|M.gilvum_PYR-GCK RVRHREPDAVALVQRVERVKAMAVGGTRPLTAAELRLLPHLATHLSLQRI
Mvan_1633|M.vanbaalenii_PYR-1 RACHREPDAVALVQRVDRVKAMAAGGTRPLTAAELRLLPHLASHLSLQRV
MAB_0060|M.abscessus_ATCC_1997 KRAQP--------------------AGPSLSTREREVLRMIAAGQTVPAI
MAV_0872|M.avium_104 QRAEP--------------------TGPVLSAREREVLHRIARGQSIPAI
TH_3184|M.thermoresistible__bu RLQRDE---------------FWPGARHGLTQRESEILSYVVNGLSNRGI
Mb3107c|M.bovis_AF2122/97 GIATMTAELDEDSAVRLLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAA
Rv3080c|M.tuberculosis_H37Rv GIATMTAELDEDSAVRLLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAA
MMAR_2576|M.marinum_M GIVTLTYELDEASAIRLLSAGGSEQDRADAHRRARDLLTGIDATLRPWAA
MSMEG_4430|M.smegmatis_MC2_155 VAVHPMIGSAGQGRRVAVAAYNDEHIAEDLTSKELEVLRLLATRLSRRDI
MLBr_01753|M.leprae_Br4923 YAQRGRGN-----------RKRPTTGWESLTPAEHNVIRLVSEGLDTKDI
MUL_2876|M.ulcerans_Agy99 DLDLRKIEPVERSPAARSLAEVQTRVMAMLTRREVEVLRLMAAGRTNQQI
: :
Mflv_4809|M.gilvum_PYR-GCK AEELVIGRETAKSQATSIYRKLGVSSRGQAVSEAIRIGLLAD----
Mvan_1633|M.vanbaalenii_PYR-1 AEELVIGRETVKSQATAIYRKLGVSSRGEAVAEAKRVGLIAD----
MAB_0060|M.abscessus_ATCC_1997 ARALFLAPSTVKTHVQRLYEKLGVGDRAAAVAEAMRRGLLE-----
MAV_0872|M.avium_104 AGELYVAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQGLLS-----
TH_3184|M.thermoresistible__bu AAKLVIGDETVKSHLRSIYRKLGVSDRAAAVATALREGIYQ-----
Mb3107c|M.bovis_AF2122/97 LQAQILHIETLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA
Rv3080c|M.tuberculosis_H37Rv LQAQILHIETLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA
MMAR_2576|M.marinum_M LRAQLLLAETLRAAGLQPDP--ESAGLAQRCNELGLVRLAVDAGLT
MSMEG_4430|M.smegmatis_MC2_155 GQRLYVSLNTVKTHQRAIYRKLGVDNRNSAVARGRELGLL------
MLBr_01753|M.leprae_Br4923 AARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN--------
MUL_2876|M.ulcerans_Agy99 ADELVISAGTVKSHVKRVLRKLHATNRAEAASAYVRLASVSEVG--
: * :