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MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIETHLPDVALLDYRMPRMDGA QVAAAVRSNGLPTRVLLISAHDESAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGL AGEIRQRAAPMAPVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTHVQRLYEKLGVSDRAAAVAEAM RQGLLD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0351 | narL | - | 100% (216) | nitrate/nitrite response regulator protein NarL |
| M. ulcerans Agy99 | MUL_3814 | - | 4e-30 | 37.33% (217) | two component transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_2423 | devR | 1e-22 | 31.22% (205) | two component transcriptional regulatory protein DevR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0867c | narL | 1e-104 | 92.13% (216) | nitrate/nitrite response transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0730 | - | 1e-83 | 74.30% (214) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0844c | narL | 1e-105 | 92.59% (216) | nitrate/nitrite response transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01286 | - | 5e-14 | 32.74% (113) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_0060 | - | 8e-85 | 74.76% (210) | nitrate/nitrite response transcriptional regulatory protein |
| M. marinum M | MMAR_4782 | narL | 1e-115 | 99.07% (216) | nitrate/nitrite response regulator protein NarL |
| M. avium 104 | MAV_0872 | - | 2e-87 | 90.11% (182) | DNA-binding response regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_0105 | - | 2e-86 | 76.78% (211) | DNA-binding response regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3563 | - | 1e-35 | 41.63% (209) | PUTATIVE DNA-binding response regulator, LuxR family protein |
| M. vanbaalenii PYR-1 | Mvan_2836 | - | 7e-32 | 38.83% (206) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0351|M.ulcerans_Agy99 -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MMAR_4782|M.marinum_M -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
Mb0867c|M.bovis_AF2122/97 -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
Rv0844c|M.tuberculosis_H37Rv -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MAV_0872|M.avium_104 --------------------------------------MNVVGEAEDGSA
Mflv_0730|M.gilvum_PYR-GCK -------MTGPGRVRVVVGDDHPMFRDGVVRALQSSGAIDVVAEADDGTA
MSMEG_0105|M.smegmatis_MC2_155 -----MLTRMSDKVRVVVGDDHPMFREGVVRALTSSGDIDVVAEADNGAD
MAB_0060|M.abscessus_ATCC_1997 -----MQVSG-ELVRVVVGDDHPLFREGVVRALTASGQITVVAEAENGTG
TH_3563|M.thermoresistible__bu -------MGEPQQPTVMVVDDHPIWREAVARDLAEAG-LSVVATADGVAA
Mvan_2836|M.vanbaalenii_PYR-1 ---------------MMVVDDHPIWRDAVARDLADDG-FDVVATADGVAS
MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLRDEG-YDIVGEAADGQE
:*. * .
MUL_0351|M.ulcerans_Agy99 ALELIETHLPDVALLDYRMPRMDGAQVAAAVRSNGLPTRVLLISAHDESA
MMAR_4782|M.marinum_M ALELIKTHLPDVALLDYRMPRMDGAQVAAAVRSNELPTRVLLISAHDESA
Mb0867c|M.bovis_AF2122/97 ALELIKAHLPDVALLDYRMPGMDGAQVPAAVRSYELPTRVLLISAHDEPA
Rv0844c|M.tuberculosis_H37Rv ALELIKAHLPDVALLDYRMPGMDGAQVAAAVRSYELPTRVLLISAHDEPA
MAV_0872|M.avium_104 ALELIKSHQPDVALLDYRMPGMDGAQVAAAVRADGLATRVLLISAHDESA
Mflv_0730|M.gilvum_PYR-GCK ALAAIREHRPAVALLDYRMPGMDGAEVAAAVQRGALPTRVLLISAHDESA
MSMEG_0105|M.smegmatis_MC2_155 ALELIKVHRPAVALLDYRMPQLDGAQVAAAVVRDELPTRVLLVSAHDESA
MAB_0060|M.abscessus_ATCC_1997 ALELIREHRPDVALVDYRMPELDGTQVAAAVRRDELPTRVLLLSAHDDAA
TH_3563|M.thermoresistible__bu ARRRAAAVRPDVVLMDMRLPDGDGARATAEVRAVSPDSRVLVLSASEERD
Mvan_2836|M.vanbaalenii_PYR-1 AKRRAAVVQPAVVLMDMRLADGDGAQATAEVLAVSPSSRVLVLSASDERD
MLBr_01286|M.leprae_Br4923 AVELAERHKPDLVIMDVKMPRRDGIDAASEIASKRIAP-IVVLTAFSQRD
* * :.::* ::. ** ..: : . :::::* .:
MUL_0351|M.ulcerans_Agy99 IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
MMAR_4782|M.marinum_M IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
Mb0867c|M.bovis_AF2122/97 IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
Rv0844c|M.tuberculosis_H37Rv IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
MAV_0872|M.avium_104 IVYQALQQGAAGFVLKDSTRSEIVKAVLDCAQGRDVVAPALVGGLAAEIR
Mflv_0730|M.gilvum_PYR-GCK IVYRALADGAAGFLPKESTRNELITAVLDCAKGRDVVAPSLAAGLAGEIR
MSMEG_0105|M.smegmatis_MC2_155 IVYSALQQGAAGFLSKESTRSELVSAVLSCAKGRDVITPHLAAGLAGEIR
MAB_0060|M.abscessus_ATCC_1997 IVYRALEEGAAGFLSKESTRTELVGAVLDCARGRDVVAASLTAGLAGEIR
TH_3563|M.thermoresistible__bu DVLEAVKAGATGYLVKSASKTELVDAVHATAQGRAVFTPGLAGLVLGEYR
Mvan_2836|M.vanbaalenii_PYR-1 DVLEAVKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEFR
MLBr_01286|M.leprae_Br4923 LVERARDAGAMAYLVKPFTISDLIPAIALAMSRFSELT-----ALEREVA
* * ** .:: * : :: *: .: : *
MUL_0351|M.ulcerans_Agy99 --QRAAPMA---PVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTHV
MMAR_4782|M.marinum_M --QRAAPMA---PVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTHV
Mb0867c|M.bovis_AF2122/97 --QRAAPVA---PVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHV
Rv0844c|M.tuberculosis_H37Rv --QRAAPVA---PVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHV
MAV_0872|M.avium_104 --QRAEPTG---PVLSAREREVLHRIARGQSIPAIAGELYVAPSTVKTHV
Mflv_0730|M.gilvum_PYR-GCK --RRAEPEG---PALSPREREVLVLIAAGSTIPAMARELFLAPSTVKTHV
MSMEG_0105|M.smegmatis_MC2_155 --RRNEPDV---PVLSPREREVLNLIAQGRSIPAMAKELYLAPSTVKTHV
MAB_0060|M.abscessus_ATCC_1997 --KRAQPAG---PSLSTREREVLRMIAAGQTVPAIARALFLAPSTVKTHV
TH_3563|M.thermoresistible__bu RISRQPGAGPDAPRLTERETEILRYVAKGLTAKQIAAQLSLSHRTVENHV
Mvan_2836|M.vanbaalenii_PYR-1 RIERDSPAG---PTLTERETEILRHVAKGLTAKQIASRLSLSHRTVENHV
MLBr_01286|M.leprae_Br4923 -------------TLADR-LETRKLVERAKGLLQVKQGMTEPEAFKWIQR
*: * * : . : : . :
MUL_0351|M.ulcerans_Agy99 QRLYEKLGVSDRAAAVAEAMRQGLLD
MMAR_4782|M.marinum_M QRLYEKLGVSDRAAAVAEAMRQGLLD
Mb0867c|M.bovis_AF2122/97 QRLYEKLGVSDRAAAVAEAMRQRLLD
Rv0844c|M.tuberculosis_H37Rv QRLYEKLGVSDRAAAVAEAMRQRLLD
MAV_0872|M.avium_104 QRLYEKLGVSDRAAAVAEAMRQGLLS
Mflv_0730|M.gilvum_PYR-GCK QRLYEKLGVSDRGAAVAEAMRRKLLD
MSMEG_0105|M.smegmatis_MC2_155 QRLYEKLGVSDRAAAVAEAMRRHLLD
MAB_0060|M.abscessus_ATCC_1997 QRLYEKLGVGDRAAAVAEAMRRGLLE
TH_3563|M.thermoresistible__bu QATFRKLQVANRVELARYAIEHGLDE
Mvan_2836|M.vanbaalenii_PYR-1 QATFRKLQIGNRVELARYAIEHGLDE
MLBr_01286|M.leprae_Br4923 AAMDRRTTMKRVAEVVLETLDTPKDT
.: : . ::