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AEDAPYTTQAHPAQRGGISGIPGELIDAGFENVAEVGRGGFGIVYRAFQPSLDRTVAVKVLTADLDPDNL DRFLREQRAMGRLSGHPHIVTILEVGTTATGRPFLVMPYHQNDSLEALVRRNGPLDWGEVVRLGVKVAGA LEAAHRVGTLHRDVKPGNILISDYGEPQLTDFGIARIAGGFQTSTGVITGSPAFTAPEVLEGAPPTPQSD VYSLGATLFSAITGHAAFERRRGEKVVAQFLRITSQPIPNLREEGLPADVASVIEKAMARDPADRPDSAA AFGEQLRQVQREHGVAVDEMAHPVELGAPRSDLATARSTYGHDTHATPAPPTPATKYRPQVPARSRVSRR RLTDALSAAGRRRLILIYAPSGYGKSTLAAQWREELVRAGVAVAWLTIDDDDNNPVWFLAHLLESIRRVH PGVAESLDHVLEEHGDDGSRYLLTSIIDALHDADEPTTLIVDDWQRVSDSQTIAALSFLLEHGCHHLQII VTSWSRTGLPLSRLRLADELVEIDSAALRFDSGEATSFFDSLGGLSLTGNDVAALTESTDGWAAGLQLAG LSVRGGADASTLVGKLCGTSEVIGEFLAENVLASLEPEIVDFVLATSIPERICADLASALAQVPRGQALL EQVAQRGLFLQPVDGEPGWFHYHQMFAEFLRRRLERDDPQRVAQLHRTAALWLKEHDRLHDAVKHALAAG DPALAVDFVEDDETNLLEQSKMTTLLEIVKKLPPRLIVSRERLQLAIAWANILLQRKVPADAALNLFTKA LDHADPATQADLRVEADVLQAVADTFADRIDRVDTLVAEALSRPQTFHPRVPAVAGNVSAFAALYRFQFD QVRRLLAWATPYREMMGPFVSVYARCYLGLAAKFALDIATALAEFRRAVEIAQSCGTNSNATRIAGAFLG EMLHDVGELTEAKLLLDESYRLGPEGGGVDYLVARFVAGARVNAAHGDCAAAAERLEAGMAVADQLHLPR LSAAINHERVRLGIGLSPSVSARLRDTRHNSSDDGIVTLTYELDEASAIRLLSAGGSEQDRADAHRRARD LLTGIDATLRPWAALRAQLLLAETLRAAGLQPDPESAGLAQRCNELGLVRLAVDAGLT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2576 | pknK | - | 100% (1109) | serine/threonine-protein kinase transcriptional regulatory protein PknK |
| M. marinum M | MMAR_3547 | - | 3e-92 | 45.43% (438) | serine/threonine-protein kinase transcriptional regulatory |
| M. marinum M | MMAR_0366 | pknK_3 | 1e-91 | 39.86% (567) | serine/threonine-protein kinase transcriptional regulatory |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3107c | pknK | 0.0 | 65.13% (1104) | serine/threonine-protein kinase transcriptional regulatory |
| M. gilvum PYR-GCK | Mflv_4809 | - | 2e-37 | 28.71% (418) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv3080c | pknK | 0.0 | 65.22% (1104) | serine/threonine-protein kinase transcriptional regulatory |
| M. leprae Br4923 | MLBr_00897 | - | 2e-39 | 34.63% (335) | serine-threonine protein kinase |
| M. abscessus ATCC 19977 | MAB_0034c | - | 1e-38 | 33.63% (333) | putative serine/threonine-protein kinase PknA |
| M. avium 104 | MAV_2318 | - | 1e-40 | 36.14% (332) | serine-threonine protein kinase |
| M. smegmatis MC2 155 | MSMEG_0529 | - | 0.0 | 50.63% (1108) | serine/threonine-protein kinase PknK |
| M. thermoresistible (build 8) | TH_2610 | - | 7e-37 | 33.44% (317) | PUTATIVE serine/threonine protein kinase |
| M. ulcerans Agy99 | MUL_4753 | pknK_3 | 9e-91 | 39.89% (554) | serine/threonine-protein kinase transcriptional regulatory |
| M. vanbaalenii PYR-1 | Mvan_1076 | - | 2e-94 | 54.21% (321) | protein kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3107c|M.bovis_AF2122/97 -------MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGGFG
Rv3080c|M.tuberculosis_H37Rv -------MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGGFG
MMAR_2576|M.marinum_M -------MAEDAPYTTQAHPAQRGGISGIPGELIDAGFENVAEVGRGGFG
MSMEG_0529|M.smegmatis_MC2_155 -------MVRNDP-----LPTQRDLPAGIPAELVAAGFEDPDEIGRGGFG
MLBr_00897|M.leprae_Br4923 --------------------------------MLDGRYLLKAKIGNGGTA
MAV_2318|M.avium_104 MAQAESPGSSSGRPGPHRRQAQAESPGSFAGTLLDGRYLIESKIASGGTS
TH_2610|M.thermoresistible__bu -------------------VETYQQSDPFAGTVLDGRYRIDTLIATGGMS
MAB_0034c|M.abscessus_ATCC_199 -------------------------MTVRVGETLSGRYRLQRLIATGGMG
MUL_4753|M.ulcerans_Agy99 ----------------------------------MDGFADAAEVGRGGFG
Mvan_1076|M.vanbaalenii_PYR-1 ------------------------MAGEIAYELAAAGFVDAVEVGRGGGG
Mflv_4809|M.gilvum_PYR-GCK ----------MGRPRIADRVVPRPDLLKRLESSAGGDLVVLTAPAGYGKT
. *
Mb3107c|M.bovis_AF2122/97 VVYRCVQPSLDRAVAVKVLSTDLDRDN--LERFLREQRAMGRLSGHPHIV
Rv3080c|M.tuberculosis_H37Rv VVYRCVQPSLDRAVAVKVLSTDLDRDN--LERFLREQRAMGRLSGHPHIV
MMAR_2576|M.marinum_M IVYRAFQPSLDRTVAVKVLTADLDPDN--LDRFLREQRAMGRLSGHPHIV
MSMEG_0529|M.smegmatis_MC2_155 VVYRCVQRALDRTVAVKVLTTDLEPDN--LERFMREQVAMGKLSGHPNIV
MLBr_00897|M.leprae_Br4923 TVYRGVDIRLDRPVAVKVMDSRYTGDEQLLTRFQLEARSVARLK-DPGLV
MAV_2318|M.avium_104 TVYRGVDTRLDRPVAVKVMDPRYAGDEQFLTRFQREARAVARLK-DPGLV
TH_2610|M.thermoresistible__bu AVYRGLDLRLDRPVAVKVMDSRYAGDQQFLTRFQREARAAARLK-DPGLV
MAB_0034c|M.abscessus_ATCC_199 QVWEGTDSRLGRKVAVKVLKAEFSSDPEFIERFRAEARTVAMLN-HPGIA
MUL_4753|M.ulcerans_Agy99 VVYRCRQVDLDRVVAIKVLTIDLDENR---PRFEREQRAMAKLTGHPNIV
Mvan_1076|M.vanbaalenii_PYR-1 VVYRCHQQSLGRTVAIKVLASSLDEDD--RERFLREGYAMGGLSGHPNIV
Mflv_4809|M.gilvum_PYR-GCK TVTAMWDAEDRRQFAWARIDHLDDDPG---HLLLHIATAVVRLGAGDDHL
* : * .* : : : *
Mb3107c|M.bovis_AF2122/97 TVLQVG----VLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVK
Rv3080c|M.tuberculosis_H37Rv TVLQVG----VLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVK
MMAR_2576|M.marinum_M TILEVG----TTATGRPFLVMPYHQNDSLEALVRRNGPLDWGEVVRLGVK
MSMEG_0529|M.smegmatis_MC2_155 NIFQVG----TIASGRPYIVMQYHPHGSLSAKIQAAGPLGWRGALRIGVK
MLBr_00897|M.leprae_Br4923 AVYDQG----IDARHP-FLVMELIEGGTLRELLAERGPMPPHAVVAVLRP
MAV_2318|M.avium_104 AVYDQG----LDARHP-FLVMELIEGGTLRELLGERGPMPPYAVAAVLRP
TH_2610|M.thermoresistible__bu AVYDQGP--GSPASHPPYLVMELIEGGTLRELLRERGPMPPHAAAAVLAP
MAB_0034c|M.abscessus_ATCC_199 SVYDYGETDIDSEGRTAYLVMELIHGEPLNSVLKRTGRLSLRHSLDMLEQ
MUL_4753|M.ulcerans_Agy99 SVLQIG----ETRDGHPYLVMPYCRRGSVQTEISRLGRLSLADILQLGVA
Mvan_1076|M.vanbaalenii_PYR-1 NILQVG----MTEQDRPFIVMPYHARGSLADQVRREGRIPWPDALRIGVK
Mflv_4809|M.gilvum_PYR-GCK LNYLRGP-GREPEHLLPAVVRLLEEFGPIVVILDDVHKLSTPQSISALHA
* :* .: : :
Mb3107c|M.bovis_AF2122/97 LAGALEAAHRVGTLHRDVKPGNILLTDYGEPQLTDFGIAR-IAGGFETAT
Rv3080c|M.tuberculosis_H37Rv LAGALEAAHRVGTLHRDVKPGNILLTDYGEPQLTDFGIAR-IAGGFETAT
MMAR_2576|M.marinum_M VAGALEAAHRVGTLHRDVKPGNILISDYGEPQLTDFGIAR-IAGGFQTST
MSMEG_0529|M.smegmatis_MC2_155 MAGALETAHQRDTLHRDVKPANILLTEYGEPQLTDFGIAR-IAGGFETAE
MLBr_00897|M.leprae_Br4923 VLGGLAAAHRAGLVHRDVKPENILISDDGDVKIADFGLVRAVAAAGITST
MAV_2318|M.avium_104 VLGGLAAAHRAGLVHRDVKPENVLISDDGEVKIADFGLVRAVAAAGITSA
TH_2610|M.thermoresistible__bu VLGGLAVAHRAGLVHRDIKPENVLISDDGEVKIADFGLVRAVAEAKITSD
MAB_0034c|M.abscessus_ATCC_199 TGRALQVAHAAGLVHRDVKPGNILITPTGQVKLTDFGIAKAVDAAPVTQT
MUL_4753|M.ulcerans_Agy99 LAAGLESAHRLDILHRDIKPANVLLTDFGEPALTDFGLAH-MAGGFRTAT
Mvan_1076|M.vanbaalenii_PYR-1 LCGALETAHRTGTLHRDIKPANVLVNDYGDPQLSDFGTAR-IVGGYKTVT
Mflv_4809|M.gilvum_PYR-GCK FVDAAPLTTTVALLGRFLLP-----LDIARRRLAGNLVEVDQDALRLTAE
. : : * : * . ::. *
Mb3107c|M.bovis_AF2122/97 GVIAGSPAFTAPEVLEGASPTPASDVYSLGATLFCVLTGHAAYERRSGER
Rv3080c|M.tuberculosis_H37Rv GVIAGSPAFTAPEVLEGASPTPASDVYSLGATLFCALTGHAAYERRSGER
MMAR_2576|M.marinum_M GVITGSPAFTAPEVLEGAPPTPQSDVYSLGATLFSAITGHAAFERRRGEK
MSMEG_0529|M.smegmatis_MC2_155 GAIMGSPAYTAPEVLLGESPTVASDVYSLASTVFTASTGHAVFERGKGEQ
MLBr_00897|M.leprae_Br4923 SVILGTVAYLSPEQVRDGDASPRSDVYSAGIMTYELLTGHTPFTGDSALS
MAV_2318|M.avium_104 SVILGTAAYLSPEQVRDGAATPRSDVYAAGILAYELLTGRTPFTGDSTLA
TH_2610|M.thermoresistible__bu SVILGTAAYLSPEQVATGDATPRSDVYAVGILTYEMLTGNTPFTGDNALA
MAB_0034c|M.abscessus_ATCC_199 GMVMGTAQYIAPEQALGHDATPASDVYSLGVVGYEAVSGKRPFSGDGALT
MUL_4753|M.ulcerans_Agy99 GLFTASPAFTASELARGGEPDRASDVYGVGATLFCALTGHPPFERRKGES
Mvan_1076|M.vanbaalenii_PYR-1 GFFTGTLSYTAPEVLTGKPPTVEADVYSLGATLYAMIAGKAAHERNTDEE
Mflv_4809|M.gilvum_PYR-GCK ETVAALESVRGPS---DDATVATVIDLCEGWAAGVILTAMALRDGTAPEA
. . ... . . :.
Mb3107c|M.bovis_AF2122/97 VIAQFLRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGEE
Rv3080c|M.tuberculosis_H37Rv VIAQFLRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGEE
MMAR_2576|M.marinum_M VVAQFLRITSQPIPNLREEGLPADVASVIEKAMARDPADRPDSAAAFGEQ
MSMEG_0529|M.smegmatis_MC2_155 MVAQFLRITRHPAPNLRDADLPADLSAAIEQAMSRTISDRPESAQAFGEQ
MLBr_00897|M.leprae_Br4923 IAYQRLEIDVPRASTVI-TGVPQQFDELVARATVRDPSGRYADAIEMAAQ
MAV_2318|M.avium_104 IAYRRLDADVPPPSAAI-DGVPAQFDDFVQRATARDPADRYADAVEMGAD
TH_2610|M.thermoresistible__bu LAYQRLDNDVPPPSSAI-SGVPPQFDELVATATARDPADRFADAHDMAAA
MAB_0034c|M.abscessus_ATCC_199 VAMKHIKETPSPLP----ADLPPNVRELIEITLVKNPQNRYTSGGPFADA
MUL_4753|M.ulcerans_Agy99 VIAQILRVANDPVPDLAEYDVAEDVASVVNRALSRDPAARP-TMVELGEA
Mvan_1076|M.vanbaalenii_PYR-1 LIAHYLRITSQPVPDLRHLGIPSDVCSAIEKAMSLESAARFDSAAEFGRA
Mflv_4809|M.gilvum_PYR-GCK LAGRNNLVVEYVVEEVIDRVDDDTRSFLLESAMLDRFTAEHLDAVLGRVD
: : : : .
Mb3107c|M.bovis_AF2122/97 LRDVQRRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPT
Rv3080c|M.tuberculosis_H37Rv LRDVQRRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPT
MMAR_2576|M.marinum_M LRQVQREHGVAVDEMAHPVELGAPRSDLATARSTYGHD---THATPAPPT
MSMEG_0529|M.smegmatis_MC2_155 LRELQRRHGLPVDDMPIPIAPPTDR---PSSIASPTPSSGYPVRTLTPPA
MLBr_00897|M.leprae_Br4923 VDSIAEELALPPFRVPAPRNT-----------AQYRSAALHRGHMVERPV
MAV_2318|M.avium_104 LDAIADELALPGFRVPAPRNS-----------ALHRSAALHR-------E
TH_2610|M.thermoresistible__bu VADLVAELELPPFRVPAPRNS-----------AQHLSA------------
MAB_0034c|M.abscessus_ATCC_199 VAAVRAGRRPPRPNQAPTISR-----------ATPAAIPPAT--------
MUL_4753|M.ulcerans_Agy99 IQSLQAAHGQAVDAMALEGGK----------RSTSVSSESAWHVSARQTR
Mvan_1076|M.vanbaalenii_PYR-1 LQEAQRHNGLTADTMAIGEPTPAAAP--PEGTQALPLSVPSDSVVLPPIP
Mflv_4809|M.gilvum_PYR-GCK AAWMLEQLATSGNPFLISLDS--------------------------QGD
.
Mb3107c|M.bovis_AF2122/97 PATKYRPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQW
Rv3080c|M.tuberculosis_H37Rv PATKYRPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQW
MMAR_2576|M.marinum_M PATKYRPQVPARSRVSRRRLTDALSAAGRRRLILIYAPSGYGKSTLAAQW
MSMEG_0529|M.smegmatis_MC2_155 PATRFQMPSSAKRLVERARLIDVLRAQRDKKLTVIHGPTGFGKSTLAVQW
MLBr_00897|M.leprae_Br4923 EQQVQPVVNAPMPHSTRQFTRRLRDCSAPRRPARPDIDS---PEEYEYEP
MAV_2318|M.avium_104 AGRRAPGAEPPARHPTRHLTRGPEEWPQPEPPAHVGAEPDDDEDDYEYQS
TH_2610|M.thermoresistible__bu ---------------IRQHSQSARPTTTLQPPXXXGAGG----RARVATE
MAB_0034c|M.abscessus_ATCC_199 --QVRPAVGAPSRVAPPTSRTRQPTGSHRPPPPRRGTFSPGQKALMWAAA
MUL_4753|M.ulcerans_Agy99 GNLPAKLAGFVGRQAELAELGALISTSRPVTLTGVGGVGKTSLAVQAAGE
Mvan_1076|M.vanbaalenii_PYR-1 AAAPPASPPAPPPPPPPDMFARSPSNSPPITPWPVAPPPYPASVAPAKNR
Mflv_4809|M.gilvum_PYR-GCK SFRYHHLFGDVLRARLRASEPARFRELASRAADLLEREGDIDGALVHALE
Mb3107c|M.bovis_AF2122/97 REELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLE
Rv3080c|M.tuberculosis_H37Rv REELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLE
MMAR_2576|M.marinum_M REELVRAGVAVAWLTIDDDDNNPVWFLAHLLESIRRVHPGVAESLDHVLE
MSMEG_0529|M.smegmatis_MC2_155 AKQLAADGVAVAWLTVDDDDNNVVWFLSHVIEAIRSVMPALASDLGDVLE
MLBr_00897|M.leprae_Br4923 VPDRFAGIAISEFIWARQHARRMVLIWVGVVVAIAGLVATVAWTIGSHLS
MAV_2318|M.avium_104 VTGEFAGIPISEFVWARQHNRRMVLVWLALVLAVTGMVATAAWTIGRNLN
TH_2610|M.thermoresistible__bu IGDRIG-------IVDQPPTAR-------------GRHANAVRTAFRNDE
MAB_0034c|M.abscessus_ATCC_199 VLGIFAIIIAALILLQASEKKNQTPSIPATVSGSETPSSPGSASPGALAP
MUL_4753|M.ulcerans_Agy99 HVSHFHDGVWLVDIGELSDGALLAGLAARMLGIRDQGARPLTEVLTDALA
Mvan_1076|M.vanbaalenii_PYR-1 KKTLIALAAAAAAVLLVIGTVVIVASRDNRSGEAGGVTTAARPTAEAQPG
Mflv_4809|M.gilvum_PYR-GCK AGDRARAAALVGREAVRLGFDGRAGVLARRLGMLDARTFAEQPDAAVARA
Mb3107c|M.bovis_AF2122/97 EHGDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDN
Rv3080c|M.tuberculosis_H37Rv EHGDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDN
MMAR_2576|M.marinum_M EHGDDGSRYLLTSIIDALHDADEPTTLIVDDWQRVSDSQTIAALSFLLEH
MSMEG_0529|M.smegmatis_MC2_155 EHGDDAERYVLTSLINDIHSSGRRMTLVIDDWHRVTDPATIAALRYLLDN
MLBr_00897|M.leprae_Br4923 GLL-----------------------------------------------
MAV_2318|M.avium_104 GLF-----------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 ANIVALLPDAEPDPIPGTKSP-----------------------------
MUL_4753|M.ulcerans_Agy99 ERDALVIFDGCEHVIDHAAQLIDTLLQGCPQLHILATSRELLGIGGEAVL
Mvan_1076|M.vanbaalenii_PYR-1 WRPIADSRIPLAAAAATEADGTIWIFGGMGADNRVSGAHEGYDPAIDSWK
Mflv_4809|M.gilvum_PYR-GCK WLGVTTADAELIQRSLMLALHSDHGGPLADGTPSVSVAVALISSLVGVGG
Mb3107c|M.bovis_AF2122/97 GCHHLQLIVTSWSRAGLPVGRLRIGDELAEIDSAALR------FDTDEAA
Rv3080c|M.tuberculosis_H37Rv GCHHLQLIVTSWSRAGLPVGRLRIGDELAEIDSAALR------FDTDEAA
MMAR_2576|M.marinum_M GCHHLQIIVTSWSRTGLPLSRLRLADELVEIDSAALR------FDSGEAT
MSMEG_0529|M.smegmatis_MC2_155 VASGLTVVVTSRTQSGLPMSRMRMQGEIVEIDATALR------FDVSESG
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 ALSPLPYPDAASVSSRSSVARYDAVALFVERARTARPGFTLTQRNAAAVA
Mvan_1076|M.vanbaalenii_PYR-1 GGEALPVPVQRAMSVTWQDTPVVLGGWRSEGADTKVATDQVWRVVNSRWV
Mflv_4809|M.gilvum_PYR-GCK VAEVIRHADTVRAAGDNLVNPWWGAATVMKGAAEAMR-------------
Mb3107c|M.bovis_AF2122/97 ALLNDAGG-LRLPRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRG
Rv3080c|M.tuberculosis_H37Rv ALLNDAGG-LRLPRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRG
MMAR_2576|M.marinum_M SFFDSLGG-LSLTGNDVAALTESTDGWAAGLQLAGLSVRGGADASTLVGK
MSMEG_0529|M.smegmatis_MC2_155 SFLVDLAG-LDLDQTDVEELTEKTDGWVAALQLASLTLRDRDDPVQLIET
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 RICERLDG-LPLAIELAAARLRAVSVEQIADRLSDRFGLLTRGQRGAPTR
Mvan_1076|M.vanbaalenii_PYR-1 QLPPLLQPRAAAAAAVVGDRIVVTGGVDAAGKVLDTTEVYDGSGWTQAAP
Mflv_4809|M.gilvum_PYR-GCK ---GQGGRARLLLESALPVIEDLPGFHAAALAHLALLDLAAGDDEAAVER
Mb3107c|M.bovis_AF2122/97 LSGASDVIHEFLSENVLDTLEPELREFLLVASVTERTCGGLASALAGITN
Rv3080c|M.tuberculosis_H37Rv LSGASDVIHEFLSENVLDTLEPELREFLLVASVTERTCGGLASALAGITN
MMAR_2576|M.marinum_M LCGTSEVIGEFLAENVLASLEPEIVDFVLATSIPERICADLASALAQVPR
MSMEG_0529|M.smegmatis_MC2_155 MTGRHHVISEFLAENVLETLEPSTLDFLLATSIPERICGGLASALTDVPD
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 QQTLSYCIDWSYDHCTPIQQQLWARLSVFAGSFDLDAAQYVAPQDMDADD
Mvan_1076|M.vanbaalenii_PYR-1 MPTPRQLLAAASDGELVYAIGGTNGTADLATVEAYDPAADTWTAMPALPE
Mflv_4809|M.gilvum_PYR-GCK CDAARTLADKYDLSDVVPMIVVYSTSAVMSARVG-----DVPAALHAVQI
Mb3107c|M.bovis_AF2122/97 GRAMLEEAEHRGLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAEL
Rv3080c|M.tuberculosis_H37Rv GRAMLEEAEHRGLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAEL
MMAR_2576|M.marinum_M GQALLEQVAQRGLFLQPVDGEPGWFHYHQMFAEFLRRRLERDDPQRVAQL
MSMEG_0529|M.smegmatis_MC2_155 GQAILEKIEERDLFLRRIDDQ--WFRYHQLFRDFLRHRLSR---ERVCDL
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 LLDELCALVDKSILIRTEDDGAVRFRLLSTMREYGNSRIDAEQYQGLQQS
Mvan_1076|M.vanbaalenii_PYR-1 PRSDFGVAVTDARLVAVGGTAAGRPLKTVTALDLTTSTWSDLPDLGTARR
Mflv_4809|M.gilvum_PYR-GCK TQTLLERLGN----------------------------------------
Mb3107c|M.bovis_AF2122/97 HRRASAWFAENGYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTL
Rv3080c|M.tuberculosis_H37Rv HRRASAWFAENGYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTL
MMAR_2576|M.marinum_M HRTAALWLKEHDRLHDAVKHALAAGDPALAVDFVEDDETNLLEQSKMTTL
MSMEG_0529|M.smegmatis_MC2_155 HRRACRWYAGQRLVREAVDHALAAGDETEAVRLVENDGLYLVSGGQMATL
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 HFDWCERLVTQAHLEWFSRKQVDWIHRLRSELPNIEEALQFGLEKAPESV
Mvan_1076|M.vanbaalenii_PYR-1 G----------AAVAAVGKSVYVIGGSTGAGDGQATSSAEALKLAPRTPQ
Mflv_4809|M.gilvum_PYR-GCK ---------------------LSARTALLGHGLLAWTAAALQDRALLSRH
Mb3107c|M.bovis_AF2122/97 LAIVQKLPTSMVVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAE
Rv3080c|M.tuberculosis_H37Rv LAIVQKLPTSMVVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAE
MMAR_2576|M.marinum_M LEIVKKLPPRLIVSRERLQLAIAWANILLQRKVPADAALNLFTKALDHAD
MSMEG_0529|M.smegmatis_MC2_155 IGLTAKLPQDIVRSNPRLQLALAWANIVLHRVPAARDALARVEATMADAG
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 LLMAAKLRN-LFVVSGKLQVGRLWVERALSTTTSAQPSGARIAALAALAM
Mvan_1076|M.vanbaalenii_PYR-1 PAAQWRSLPDAPTARLMMAYTVLDDQIWIAGGIREGETLDTVETYDTRTQ
Mflv_4809|M.gilvum_PYR-GCK LTAAERVRHREPDAVALVQRVERVKAMAVGGTRPLTAAELRLLPHLATHL
Mb3107c|M.bovis_AF2122/97 LPEATQADLRAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPG
Rv3080c|M.tuberculosis_H37Rv LPEATQADLRAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPG
MMAR_2576|M.marinum_M P--ATQADLRVEADVLQAVADTFADRIDRVDTLVAEALSRPQTFHPRVPA
MSMEG_0529|M.smegmatis_MC2_155 LSEDEIADMRAEADVVRAIADLRSDRLSGIDEHVAACLQRRDRMPPFSVA
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 FAVLQTDWPTAQSCVAQAHEHGAAVPDPIAESLLGVARGLGALLQGQVEQ
Mvan_1076|M.vanbaalenii_PYR-1 QWQSQPSLPIPLNHAVAATYRGEVVVIGGATDTITQASDKVFAFRDGTWV
Mflv_4809|M.gilvum_PYR-GCK SLQRIAEELVIGRETAKSQATSIYRKLGVSSRGQAVSEAIRIGLLAD---
Mb3107c|M.bovis_AF2122/97 TAGNTAALAAICRFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAA
Rv3080c|M.tuberculosis_H37Rv TAGNTAALAAICRFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAA
MMAR_2576|M.marinum_M VAGNVSAFAALYRFQFDQVRRLLAWATPYREMMG-PFVSVYARCYLGLAA
MSMEG_0529|M.smegmatis_MC2_155 TAATVATFAAAYRYDLDEVERIQTWAAPYYERSGDAFSIVNGLCFCGIAH
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 VQTDAEQGLAAGDFELQVLG---MWLMPLRHLAVGDPEPALRWAEKAHSV
Mvan_1076|M.vanbaalenii_PYR-1 ELASLQHARAAPAAAVVDDKLVVVGGQNDKQVVPQTEVFDGQSWTQAADM
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 RNRLDIVAALQNFRTAFEVGTAVG-AHSHAARLAGSLLAELLYETGDLAG
Rv3080c|M.tuberculosis_H37Rv RNRLDIVAALQNFRTAFEVGTAVG-AHSHAARLAGSLLAELLYETGDLAG
MMAR_2576|M.marinum_M KFALDIATALAEFRRAVEIAQSCG-TNSNATRIAGAFLGEMLHDVGELTE
MSMEG_0529|M.smegmatis_MC2_155 HLMLNNAVAEQTLRRALRIAKRSGGIHSYAGRLASSLLGEILYEKGDLAE
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 SESRVEVQMRTYSLSALAVSHLMLGDTGSAERSLREGLKLCQVIDDPWSG
Mvan_1076|M.vanbaalenii_PYR-1 PTPREHLAAVSDGVYVYTVGGRLLSADENLAAFER-----FDPESGNWEK
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 AGRLMDESYLLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGD
Rv3080c|M.tuberculosis_H37Rv AGRLMDESYLLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGD
MMAR_2576|M.marinum_M AKLLLDESYRLGPEGGGVDYLVARFVAGARVNAAHGDCAAAAERLEAGMA
MSMEG_0529|M.smegmatis_MC2_155 AERLLDEGYKLGPEGGSVDFKIARYVISARIKALQGDRLGAAQRLDEATR
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 ASYLEGLAWTAGANGNLRRAVVLMAAAAALSRSSGAGSTVIALVGSMHQQ
Mvan_1076|M.vanbaalenii_PYR-1 LPDMPTPRGSYGAAYLDGRIVVVGGEEPTRVLPTVEIYDIANRKWSTQAP
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 TAVQLGLPRLAARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATM
Rv3080c|M.tuberculosis_H37Rv TAVQLGLPRLAARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATM
MMAR_2576|M.marinum_M VADQLHLPRLSAAINHERVRLGIGLSPSVSARLRDTRHNSSD--DGIVTL
MSMEG_0529|M.smegmatis_MC2_155 VARSLSLNRLQALAEHERIRLGLPPHPEFGPMPVVSYDARREPVDAMDAI
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 CERAAREELSDAVFETARVEGESLSFDDAADVALTEP-------------
Mvan_1076|M.vanbaalenii_PYR-1 VNTPVHGQAVAAVGSTVYCIGGADRPTHEGPVATVEALDFT---------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 TAELDEDSAVRLLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAALQAQI
Rv3080c|M.tuberculosis_H37Rv TAELDEDSAVRLLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAALQAQI
MMAR_2576|M.marinum_M TYELDEASAIRLLSAGGSEQDRADAHRRARDLLTGIDATLRPWAALRAQL
MSMEG_0529|M.smegmatis_MC2_155 ALQFEEASAIRRLMASDDPAARDLACRWAREWVDRLSALNRPQALLRARR
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LHIETLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA---------
Rv3080c|M.tuberculosis_H37Rv LHIETLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA---------
MMAR_2576|M.marinum_M LLAETLRAAGLQPDP--ESAGLAQRCNELGLVRLAVDAGLT---------
MSMEG_0529|M.smegmatis_MC2_155 LLGACLAADGRTAEAKAMVATVAAQCAQLRMLRYLVDGGPQVVATLVELR
MLBr_00897|M.leprae_Br4923 --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 --------------------------------
Rv3080c|M.tuberculosis_H37Rv --------------------------------
MMAR_2576|M.marinum_M --------------------------------
MSMEG_0529|M.smegmatis_MC2_155 ADQEAGRWSPEWPEVPADFLQDAINSVAPQRY
MLBr_00897|M.leprae_Br4923 --------------------------------
MAV_2318|M.avium_104 --------------------------------
TH_2610|M.thermoresistible__bu --------------------------------
MAB_0034c|M.abscessus_ATCC_199 --------------------------------
MUL_4753|M.ulcerans_Agy99 --------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 --------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------