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M. vanbaalenii PYR-1 Mvan_1597 (-)

annotation: hypothetical protein Mvan_1597
coordinates: 1690814 - 1693510
length: 898

STDPPAEAPSQQPAWRLEYAEPGMLVYSIPGVELPKLPLVRSGGWVPGGAPSAEGLPDKHSALHYARYIG
RVGVLAAALGLGAVIAGTPGIARAEPEADSTTSSSTDSDASEASEAVTTDQEASETEEAPESEDVLESDT
GETAATEDDAEAEAEAEADAEAEAAAEAEADAEAEAEAEGGTADEDETARASGDAVEQPTATTEYTGGST
TEPAMLIPAPPDVQSPTDTEVTTGSPAVSAETDTTAPAEPTPQPAPTGAVRQALDTVLAPLAAPESPAVQ
RAETPVLWTVFAWTRRTFFNATPVVRYDDTTTSQLQNTITGRVTATDSDTPTLTLTASAPANGGTVLLRP
DGTFTYTVPTTMYAGGTDTFTVTASDADGPAHIHGLTGLLHLVSLGLVGHSGHSATATVTLDIAAVTAPI
LGTPAYQLDTAEHGTGAVPGALHVTGPEGLTYTLTGGPAEGEVTLDARTGAFIYTPTSVARHQASAEDAT
PDELADTFTITVTDNLGGTISVPVAVAIDPSNQSPTVTLVVSVPDSEGTVHVSVAVADPDNDATTYFVVH
DPAYGTLTATPDGYDYNPTAEAVRIGVRADTLTVTASDLHHGSDTETVTVPIGSDDAAPAGLLAATAYSS
TDIQLPAAATVITLRGRNYLGSLSPDRMDDHFGGMFAEDPYTMVKLTYPDSENSDAIDDAVAMLDAQLMS
TPGDIIVMGHSFGAQVCSRWMRVYARDPVRRAMADRLTFVLTGNPLRSDNGKVVGMLEIDAWIGLPTPTT
TPWQIIDVARRWDGWADWPDDSSNATAARNARAGQNYLHPNYDDVDLYDPQNTVWRNGNTTYVLTHEDDL
PMFRYWWGVPSDFESVVRAEVESAYNRPSADIPVPVRPVQSWWWQMVLRWLEIENPA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_1597--100% (898)hypothetical protein Mvan_1597
M. vanbaalenii PYR-1Mvan_5913-5e-4229.47% (621) putative outer membrane adhesin like proteiin
M. vanbaalenii PYR-1Mvan_5004-5e-4027.65% (622) hypothetical protein Mvan_5004

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1465PE161e-1128.74% (247) PE family protein
M. gilvum PYR-GCKMflv_4855-3e-3930.25% (605) YVTN beta-propeller repeat-containing protein
M. tuberculosis H37RvRv1430PE161e-1128.74% (247) PE family protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1963-6e-0623.44% (256) MmpS family protein
M. marinum MMMAR_2416lgt5e-1130.37% (191) prolipoprotein diacylglyceryl transferases Lgt
M. avium 104MAV_3172-5e-0936.21% (116) prolipoprotein diacylglyceryl transferase
M. smegmatis MC2 155MSMEG_4734-5e-1432.28% (189) hypothetical protein MSMEG_4734
M. thermoresistible (build 8)TH_3724-4e-1634.62% (208) PUTATIVE putative PE-PPE, C-terminal domain protein
M. ulcerans Agy99MUL_1034-2e-0622.22% (252) PE family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          MGYSKYVGRVGALALALGIGTAVATPAWAESPSTSESASSESKAPQKPSS
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          RRSTPATSGDSANGGDSAGKSGSDGSTASAGGNDNDSPVEDEADIEVAPE
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          PEAAEDAPPLVDEVVEESDAHDGNSASAAPEVDSPSTAVPSDATGVSEAE
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          APAHETLASLSPDQDPEPVDTEIADAPTPLGYALAVTAPPVEPAPAPLVR
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          QPRGPVGVILGGPAAMIDIAAKALQMLFNPGPTVPGDPPLLLGVLAFVRR
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          EIQRTFFNSSPTAVADTTSTSEGLPTRISVLDNDTDPNIDDVLTVTDFTQ
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          AANGVVELNADGSFTYTPTTGYSGTDTFTYTISDEASEWHGHVAGFVRGH
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          TSTATVSVTVLPPPVNESPSAAGDSATTAEDTPAVIDVKANDSDPNGDDI
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          SIASVGTAQHGAVAVLDGKITYTPESNFHGTDTFDYTITDGDLSDTATVT
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          VTVTPVNDAPVAVHDAITVAGSSVANVINVLGNDTDPDTEVTLTVAEVGA
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          PNHGGTVTIVDGNAIAYTPAAGFSGTETFSYTVSDGELTDTATVTVSVEQ
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          VVPSNIAPSAYDNVSYYTTNENTTLNVFANDGLIEWDAFDPDGDALTAGL
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          ATGPAHGTLDLNPDGSFTYTPDFGFIGDDSFRYTVTDGASSSNIATVGIS
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          VTPAGSSNTGNNRPPRAFDDFANIRENTTLTVPAGQGLLSTRSAHDADGD
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          SLTVDLVTATTNGHVSVDADGSYTYAPNDGYVGEDSFTYTISDGQATSSA
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          ATVTILVHAASEQTAPEAYGDDQIVVQDSSLTVSTENGLTSRFNAYDNEG
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          DALTAALATGPSNGQVTVNSDGSYTYTPNDGYIGEDSFTYTVSDGQLVSA
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          AATVYIDVQSNAYNMETGITIGPDGKVYVLHGTTRSNPDGTTGGSFHLAS
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          RNSDGSLTDLVQLSGASADSLPTGLAAGSDGRIYVADHLTGSITVYDRSG
Mvan_1597|M.vanbaalenii_PYR-1       -----------------------------------------MSTDPPAEA
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               ------------------------------------------------MT
MAV_3172|M.avium_104                -------------------------------------------------M
Mflv_4855|M.gilvum_PYR-GCK          GYSPTLIASIPAAAGIALDSKGRIYVTTVDYTDPDRAVGQLWILDSTGTQ
Mvan_1597|M.vanbaalenii_PYR-1       PSQQPAWRLEYAEPGMLVYSIPGVELPKLPLVRSGGWVPGGAPSAEGLPD
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --MSFVFAVPEMVAATASD----LASLGAALSEATAAAAIPTTQVLAAAA
Rv1430|M.tuberculosis_H37Rv         --MSFVFAVPEMVAATASD----LASLGAALSEATAAAAIPTTQVLAAAA
MUL_1034|M.ulcerans_Agy99           --MSYVLTAPDLLASAATD----VDGIAATLQVANSAAAALTSGLLAAAQ
MSMEG_4734|M.smegmatis_MC2_155      ------MRDVRVGLIALLS----VMALGLVSTVVSVAAAAARTSVLIMGG
TH_3724|M.thermoresistible__bu      --------------VVAVG----ALTWGGX-GVASPAGQPERAAALRLTA
MMAR_2416|M.marinum_M               ATVLAYFPSPPRGVWHLGP----LPIRAYAFFIIIGIVMGLMIGDRRFAA
MAV_3172|M.avium_104                TKLLAYFPSPPQGVWHLGP----VPIRAYALFIIAGIVAALLIGDRRWEA
Mflv_4855|M.gilvum_PYR-GCK          IGRPIDLAGPAAGVAVASNGDVYVAGLSGGLSVYSHRVLQTNITAEDLPG
Mvan_1597|M.vanbaalenii_PYR-1       KHSALHYARYIGRVGVLAAALGLGAVIAGTPGIARAEPEADSTTSSSTDS
MAB_1963|M.abscessus_ATCC_1997      ------------------------------MSGTDNPGSGNPGEVPDLDG
                                                                                      

Mb1465|M.bovis_AF2122/97            DEVSAAIAELFGAHGQEFQALSAQASAFHDRFVRALSAAAGWYVDAEAAN
Rv1430|M.tuberculosis_H37Rv         DEVSAAIAELFGAHGQEFQALSAQASAFHDRFVRALSAAAGWYVDAEAAN
MUL_1034|M.ulcerans_Agy99           DEVSAAIAKVFSAYGQEYQAAIAQASAFHTEFTRALAAAGAAYAQAEAAN
MSMEG_4734|M.smegmatis_MC2_155      SGDPLTTDQDGLPFIRDYTSKVVGNYVIPSASRPGSGIPGGPYNAVAVIT
TH_3724|M.thermoresistible__bu      TADAIIMPGTKIGYIPSQD-------EFTAYATAVIGATAGAPGAVDYLG
MMAR_2416|M.marinum_M               RGGERGVIYDIALWMVPFGLIGGRLYHLSTDWQTYFGEGGAGLGAALRIW
MAV_3172|M.avium_104                RGGERGVIYDIALWTVPFGLVGGRLYHLATDWRTYWGPGGAGFGAAVRIW
Mflv_4855|M.gilvum_PYR-GCK          FLHGLAIGPDGTAYIANWEAVSSSGELLDGAINIVNPADPTNIKQLPGVS
Mvan_1597|M.vanbaalenii_PYR-1       DASEASEAVTTDQEASETEEAPESEDVLESDTGETAATEDDAEAEAEAEA
MAB_1963|M.abscessus_ATCC_1997      PNEEAAAPDSSGADSAAFHSQAYSAPESEQFTSPYVPYDEYETQLVD---
                                                                                      

Mb1465|M.bovis_AF2122/97            AALVDTAAT--------------GASELGSGGR-----------------
Rv1430|M.tuberculosis_H37Rv         AALVDTAAT--------------GASELGSGGR-----------------
MUL_1034|M.ulcerans_Agy99           ASLITAGVSDALTAITTPIQSLLGPAAIGTGGAGSAGALTAVSSTLMADP
MSMEG_4734|M.smegmatis_MC2_155      PAQFNSGEP-----------------------------------------
TH_3724|M.thermoresistible__bu      VPGEFWPAT-----------------------------------------
MMAR_2416|M.marinum_M               DGG-----------------------------------------------
MAV_3172|M.avium_104                DGG-----------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          DPWGVVYANG-----LLYVTSTATQSVITLDPANATPFVNPNENAGGGAL
Mvan_1597|M.vanbaalenii_PYR-1       DAEAEAAAEA----------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            -TALILGSTGTPRPPFDYMQQVYDRYIAPHYLGYAFSGLYTPAQFQPWT-
Rv1430|M.tuberculosis_H37Rv         -TALILGSTGTPRPPFDYMQQVYDRYIAPHYLGYAFSGLYTPAQFQPWT-
MUL_1034|M.ulcerans_Agy99           VVALIMGGTSVPLPGPGYVSDINNNYIQPLFSGAIPQALFTPEQFWPVTP
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               -------------------------------------------------L
MAV_3172|M.avium_104                -------------------------------------------------L
Mflv_4855|M.gilvum_PYR-GCK          DPYTYDVKTGIALGPTGDTFVIRGSVTYSPADGSSESTFYLARQNEDGSF
Mvan_1597|M.vanbaalenii_PYR-1       ---------------------------------EADAEAEAEAEGGTADE
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            GIPSLTYDQSVAEGAGYLHTAIMQQVAAGN-------------DVVVLGF
Rv1430|M.tuberculosis_H37Rv         GIPSLTYDQSVAEGAGYLHTAIMQQVAAGN-------------DVVVLGF
MUL_1034|M.ulcerans_Agy99           GLGNLTFNQSVAQGVTLLNDAINTQLALGN-------------KVVAFGY
MSMEG_4734|M.smegmatis_MC2_155      GDTSLTFDDSVAAGAGKLATCIESGDECDINEDLGSDRPAPGDNLVVFGY
TH_3724|M.thermoresistible__bu      GLDSLTFDASVAXGQAMLTPMVDGAIESDT-------------PIVVFGH
MMAR_2416|M.marinum_M               GIWGAVTLGTVGAWIGCRRRGIPLPAFLDA---------------VAPGV
MAV_3172|M.avium_104                GIWGAVALGAVGAWIGCRRHGIPLPAFADA---------------LAPGI
Mflv_4855|M.gilvum_PYR-GCK          SDLAEIDGSPTSLAVGPDGRLFVTDNETGIVTMYDPSDGYSARAVAAIPN
Mvan_1597|M.vanbaalenii_PYR-1       DETARASGDAVEQPTATTEYTGGSTTEPAMLIPAPPDVQSPTDTEVTTGS
MAB_1963|M.abscessus_ATCC_1997      GEEPPPPRWPWVVGVAAIIAAITLVASVAL-------------------L
                                    .        .                                        

Mb1465|M.bovis_AF2122/97            SQGASVATLEMRHLASLPAGVAPSPDQLSFVLLGNPNNPNGGILARFPG-
Rv1430|M.tuberculosis_H37Rv         SQGASVATLEMRHLASLPAGVAPSPDQLSFVLLGNPNNPNGGILARFPG-
MUL_1034|M.ulcerans_Agy99           SQSATIVNNEILALMAMGTG-APDPGDLSFIMVGAPNNPDGGLLARFPG-
MSMEG_4734|M.smegmatis_MC2_155      SQSAAIATLEKARLAALYP-YGEGP-DVSFILTANGNRPNGGFLARGPKG
TH_3724|M.thermoresistible__bu      SQSAVIATKEKQRLLAEYPDPDTAP-DVTFVMVANPNRPNGGLLARFPG-
MMAR_2416|M.marinum_M               VMGQAIGRLGNYFNQELYGRETTVPWGLEIFYR---RDPSGFVDVHSLDG
MAV_3172|M.avium_104                ILAQAIGRLGNYFNQELYGRETTLPWGLEIFYR---RDPSGYIDPHSLDG
Mflv_4855|M.gilvum_PYR-GCK          AAGIAVDASGRIFVTTVTSDESGEPTGQLWILDATGSQIGQPVDLRLPSA
Mvan_1597|M.vanbaalenii_PYR-1       PAVSAETDTTAPAEPTPQPAPTGAVRQALDTVLAPLAAPESPAVQRAETP
MAB_1963|M.abscessus_ATCC_1997      VAGRSDETNGAAKSSTVIPTPSTTPWNEIITTTTPPPPPPPPPPTTEPPP
                                                                                      

Mb1465|M.bovis_AF2122/97            ----LYLQSLGLTFNG--ATPDTD-YATTIYTTQYDGFADFP--KYPLNI
Rv1430|M.tuberculosis_H37Rv         ----LYLQSLGLTFNG--ATPDTD-YATTIYTTQYDGFADFP--KYPLNI
MUL_1034|M.ulcerans_Agy99           ----FYIPFLDVSFNG--ATPAANPYPTSIFTAQYDGIAHAP--QYRLNI
MSMEG_4734|M.smegmatis_MC2_155      VTIPLGTPGGGVTFNGSTPT--DTQYSTIDVAIQYDGWADQP--INPANL
TH_3724|M.thermoresistible__bu      ----LYIPILGVTFNGATPAPADGPFDSYDVAREFDGWADFP--RYPLNL
MMAR_2416|M.marinum_M               ----VSTGQVAVVVQPTFLYELIWNLLVFAALIYLDRRFTIG--HGRLFA
MAV_3172|M.avium_104                ----VSTGQVALVVQPTFLYELLWNLLIFVALLYADRRLTLG--HGRLFA
Mflv_4855|M.gilvum_PYR-GCK          G---VAVASNGNVYAAG-LFGGLAIFDPATELLETISSTDLPGFLHGIAV
Mvan_1597|M.vanbaalenii_PYR-1       VLWTVFAWTRRTFFNATPVVRYDDTTTSQLQNTITGRVTATDSDTPTLTL
MAB_1963|M.abscessus_ATCC_1997      P---PPPPVVTETVTVEPPPPPPPPVTTHEAPPPVTTTTTPPP-PPPPTT
                                                                                      

Mb1465|M.bovis_AF2122/97            LADVNALLGIYYSHSLYYGLTP-EQVASGIVLPVSSPDT-----------
Rv1430|M.tuberculosis_H37Rv         LADVNALLGIYYSHSLYYGLTP-EQVASGIVLPVSSPDT-----------
MUL_1034|M.ulcerans_Agy99           LSDINAIMGYFYVHGNYPDLMS-GQAIQ---LPTSPGYTG----------
MSMEG_4734|M.smegmatis_MC2_155      LAVANANAGQRLLHPHYADYSLGSPGIIDQ------GQYG----------
TH_3724|M.thermoresistible__bu      VATANAILGIYYLHGGYYELLTENPDILDDPERTIVQQYG----------
MMAR_2416|M.marinum_M               SYVALYCVGRFCVELLRDDTATHIAGIRINSFTSTFVFIG----------
MAV_3172|M.avium_104                LYVAGYCVGRFCVELLRDDTATHIAGIRINSFTSTFVFIG----------
Mflv_4855|M.gilvum_PYR-GCK          GPDGTAYIGTWEGSNAYGDLLNGAIIIVKPGEPTTIKQVTGVSQPWGIAF
Mvan_1597|M.vanbaalenii_PYR-1       TASAPANGGTVLLRPDGTFTYTVPTTMYAGGTDTFTVTAS----------
MAB_1963|M.abscessus_ATCC_1997      TTPAGPRQITYSVTGSKAPLDRISITWTDGSGRTRVNPN-----------
                                                                                      

Mb1465|M.bovis_AF2122/97            ------------NTTYILLPNEDLPLLQPLRGI--VPEPLLDLIEPDLRA
Rv1430|M.tuberculosis_H37Rv         ------------NTTYILLPNEDLPLLQPLRGI--VPEPLLDLIEPDLRA
MUL_1034|M.ulcerans_Agy99           ------------NTDYYMYLTQDLPLVQPIRDIPYAGPPLADLIQPQLRV
MSMEG_4734|M.smegmatis_MC2_155      ------------DTRYLMIPTDTLPLLYELSQTPIVGSFLADVLDAPLRV
TH_3724|M.thermoresistible__bu      ------------DTTYYLIRTEQLPLLRPLRDLGVP-EEFVDALEPYVRR
MMAR_2416|M.marinum_M               ------------AVVYIILAPKGREDPASVRGTAAAAEEVPEPEPAGEVA
MAV_3172|M.avium_104                ------------AVVYLMAAPKGREDPESLRGNQYVEEEPAEPEPATVAA
Mflv_4855|M.gilvum_PYR-GCK          ANGMILAVSADTQTVVTLNPADATTFIKPSSDNGSDGAGSAEFASASTAV
Mvan_1597|M.vanbaalenii_PYR-1       ----------DADGPAHIHGLTGLLHLVSLGLVGHSGHSATATVTLDIAA
MAB_1963|M.abscessus_ATCC_1997      ---------------VYIPWSITVTPISNSEIGSVSASSFLRLSQLNCTI
                                                     :                                

Mb1465|M.bovis_AF2122/97            IIELGYDRTG----YADVPTPAALFPVHIDPIAVP---------------
Rv1430|M.tuberculosis_H37Rv         IIELGYDRTG----YADVPTPAALFPVHIDPIAVP---------------
MUL_1034|M.ulcerans_Agy99           LVDLGYSDYGPGLSYADVPTPAGLLSVP-NPFAVS---------------
MSMEG_4734|M.smegmatis_MC2_155      LVESGYDRTS----SPGEPKPWTLVPAKDPLKTAADFLVA----------
TH_3724|M.thermoresistible__bu      IVDLGYDRNT----PYGEPAPVRVLPPLTPAP------------------
MMAR_2416|M.marinum_M               TAAAPAGDTE-GDEPTGLAETAKAAEVAEPETVGS---------------
MAV_3172|M.avium_104                TTEAAT---------EGVAAPADG--------------------------
Mflv_4855|M.gilvum_PYR-GCK          TMSATAAHTAAVSTSISVSTKTATTAPAMASTANTANSSYGTHVTIDLDG
Mvan_1597|M.vanbaalenii_PYR-1       VTAPILGTPAYQLDTAEHGTGAVPGALHVTGPEGLT--------------
MAB_1963|M.abscessus_ATCC_1997      TTSDGQVLSS----NNNNSAQATC--------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      -------------------------------------------IPTGWDN
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------AVAGDE
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          TPTNVTLSANGTRGYVVVGNQVKIIELGASAPVIVDSVNVGVNPNMVAVN
Mvan_1597|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------PQIGAAIGGPLTALDGLLDTVINDQLNPVVTSGIYQAGAELS
Rv1430|M.tuberculosis_H37Rv         --------PQIGAAIGGPLTALDGLLDTVINDQLNPVVTSGIYQAGAELS
MUL_1034|M.ulcerans_Agy99           --------YYL---LKGSLQAP--------------------YGAAVEIG
MSMEG_4734|M.smegmatis_MC2_155      AIEDVNGTRPFGTVRPGPFGVGGPDVDYLDPDEDLTKEASKEASKGTELA
TH_3724|M.thermoresistible__bu      -----------------------------------GPATQHNAGQGITVA
MMAR_2416|M.marinum_M               STADTEASDAVESEVGEAAEAEAPEAEAEEAEVGEVEVAEAVEGEVEEAE
MAV_3172|M.avium_104                ---------------AEAAGADATAQRPEESAEPDVEKPESEETEAEAAE
Mflv_4855|M.gilvum_PYR-GCK          SFGTVAYVTNSGDGTVSIIDKARPTPLTVTVGSNPTGIALSANGTRAYVS
Mvan_1597|M.vanbaalenii_PYR-1       --------YTLTGGPAEGEVTLDARTGAFIYTPTSVARHQASAEDATPDE
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            VAAAGYGAPAGVTNAIFIGQQVLPILVEGPGALVTADTHYLVD-------
Rv1430|M.tuberculosis_H37Rv         VAAAGYGAPAGVTNAIFIGQQVLPILVEGPGALVTADTHYLVD-------
MUL_1034|M.ulcerans_Agy99           VEAG------------LLGPESFPDTYPWVPSLNPGLNFYLGQ-------
MSMEG_4734|M.smegmatis_MC2_155      DDSSVKATLVSRLTDATEAEADAVTAKIGAVTEKTQAKVTTLT-------
TH_3724|M.thermoresistible__bu      SATSTPD----KRTPVVEAPVEEPPVQTGRSTLKREKPVSARH-------
MMAR_2416|M.marinum_M               EAEPGEVEVAEAVEGEVEAAAEAEEAEEAEEAEEAEEAEEAEPGEIEVAE
MAV_3172|M.avium_104                EPE----------------------SEETEAAEEPGEPEAEEP-------
Mflv_4855|M.gilvum_PYR-GCK          NTNSNTVSIIDYGGGVLQLPKVVANVPVGSRPTSIAVNSTGTVAYVTNEG
Mvan_1597|M.vanbaalenii_PYR-1       LADTFTITVTDNLGGTISVPVAVAIDPSNQSPTVTLVVSVPDSE------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            ------------------------AIQDLAAGDLSG-------------F
Rv1430|M.tuberculosis_H37Rv         ------------------------AIQDLAAGDLSG-------------F
MUL_1034|M.ulcerans_Agy99           ------------------------PSVTLLSLLSGG-------------L
MSMEG_4734|M.smegmatis_MC2_155      ------------------------KPRPQAADEAGDEADAEPSE-----P
TH_3724|M.thermoresistible__bu      ------------------------LVRNSLRAVPG---------------
MMAR_2416|M.marinum_M               AVEGEVEAAAEAEEAEVGEVEAVDEAAEAEAPEVGEIEAAEAVEGEVEVA
MAV_3172|M.avium_104                ------------------------EEPEAEEPEE----------------
Mflv_4855|M.gilvum_PYR-GCK          GDTVSIIRYNGSGSPSVSTVNVSAQPQSVKTDDTGTKAIVYSRGGIVTII
Mvan_1597|M.vanbaalenii_PYR-1       -----------------GTVHVSVAVADPDNDATTYFVVHDPAYGTLTAT
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            NQNLQLIPATNIA-------------------------------------
Rv1430|M.tuberculosis_H37Rv         NQNLQLIPATNIA-------------------------------------
MUL_1034|M.ulcerans_Agy99           GDIFHLIPPP----------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      SESSESEPSGSET-------------------------------------
TH_3724|M.thermoresistible__bu      --LRRGEPAATPT-------------------------------------
MMAR_2416|M.marinum_M               AEAEEAEAGEDEPKEAEEVAEAE-----------------------GSEA
MAV_3172|M.avium_104                PETEEPEADSDE--------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          NGSGSVPTATTVPGRHFSYADYPGFVAISSDGRTAFVTEHDSPRRVTIID
Mvan_1597|M.vanbaalenii_PYR-1       PDGYDYNPTAEAVRIG----------------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------LLVFAAGIPAVAAVAILTGQDFPV------
Rv1430|M.tuberculosis_H37Rv         --------------------LLVFAAGIPAVAAVAILTGQDFPV------
MUL_1034|M.ulcerans_Agy99           ----------------------VFP-------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------PETSDTKKPMTVAKDSGSEDKAVTKPADAK
TH_3724|M.thermoresistible__bu      --------------------PDVTPDVTPDAPAG---------------Q
MMAR_2416|M.marinum_M               EDKTVQAIDGGQTGVDDAGEADAEPDDDSTAAEPEVVVEQADIEEIEPQE
MAV_3172|M.avium_104                -----------------------EPE------------------------
Mflv_4855|M.gilvum_PYR-GCK          TANPGVTPRFVDLPDYSHSIVSLPDGTRAFTVAHDALWVIESKTGQATPV
Mvan_1597|M.vanbaalenii_PYR-1       ----------VRADTLTVTASDLHHGSDTETVTVPIGSDDAAPAGLLAAT
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      PEPKEKSEDTSAGKRGRHSSGLTAKPSDKESAPKHRAPDSDTASAKPSRE
TH_3724|M.thermoresistible__bu      PEPAEPNE------------------------------------------
MMAR_2416|M.marinum_M               PEAEAVAAAEATDADEGDGEPAEPASDDLDAVAAEDADVDVDATATEAEE
MAV_3172|M.avium_104                ------------------------------------------------EE
Mflv_4855|M.gilvum_PYR-GCK          YVPADNNFSQHQRIAISSDGRRVIAADNFGSLTAFYLSGGGSVKPPNLDW
Mvan_1597|M.vanbaalenii_PYR-1       AYSSTDIQLPAAATVITLRGRNYLGSLSPDRMDDHFGGMFAEDPYTMVKL
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      KNSAPKHAAAAKDDRQTKPRAAHG--------------------------
TH_3724|M.thermoresistible__bu      -SAAPPAAAEADDASE----------------------------------
MMAR_2416|M.marinum_M               SGDESPEPAADSEEPEADESAPEDSAEDTSSGESDTQSELEQSQTIEQGS
MAV_3172|M.avium_104                SGEAPEQPVAE--EPEPAPQQPE---------------------------
Mflv_4855|M.gilvum_PYR-GCK          LRNSPTASSTAVTTDSLLTKIPTSTPDTIRIQKSTDGGTTRVVVYISGVK
Mvan_1597|M.vanbaalenii_PYR-1       TYPDSENSDAIDDAVAMLDAQLMSTPGDIIVMGHSFGAQVCSRWMRVYAR
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      ---------------AAAKDAGARDKQHKQDKQDKQAASAAKK-------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               DQTSAGDGEGPPPSAAVDGDTGPTRQGWRGRLRNRMRRSGR---------
MAV_3172|M.avium_104                -----------------------TKRRWGARLRDRL--SGR---------
Mflv_4855|M.gilvum_PYR-GCK          EPSLQAAGSYWAVLRAKQGITDENMRDTINKAISDIEKDGTTVSEIMLVG
Mvan_1597|M.vanbaalenii_PYR-1       DPVRRAMADRLTFVLTGNPLRSDNGKVVGMLEIDAWIGLPTPTTTPWQII
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          FSKGGMTAQNYASKRSFLGIDIYNETYGDKVKAVITFASPLVRKADEYGY
Mvan_1597|M.vanbaalenii_PYR-1       DVARRWDGWADWPDDSSNATAARNARAGQNYLHPNYDDVDLYDPQNTVWR
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          GVDVVHLAAQNDYLPRDEFFGGVLGWVDGQQVTQASNRGVRETFINERSD
Mvan_1597|M.vanbaalenii_PYR-1       NGNTTYVLTHEDDLPMFRYWWGVPSDFESVVRAEVESAYNRPSADIPVPV
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            --------------------------------------------------
Rv1430|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_1034|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155      --------------------------------------------------
TH_3724|M.thermoresistible__bu      --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
Mflv_4855|M.gilvum_PYR-GCK          WKTIYTYDTKSFSKDPITRHSVDNYHLVAKNYDANASRWIQSKLVTSAIT
Mvan_1597|M.vanbaalenii_PYR-1       RPVQSWWWQMVLRWLEIENPA-----------------------------
MAB_1963|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1465|M.bovis_AF2122/97            -----------------------
Rv1430|M.tuberculosis_H37Rv         -----------------------
MUL_1034|M.ulcerans_Agy99           -----------------------
MSMEG_4734|M.smegmatis_MC2_155      -----------------------
TH_3724|M.thermoresistible__bu      -----------------------
MMAR_2416|M.marinum_M               -----------------------
MAV_3172|M.avium_104                -----------------------
Mflv_4855|M.gilvum_PYR-GCK          RFFKGTINEIDLDPNSPKTTKTF
Mvan_1597|M.vanbaalenii_PYR-1       -----------------------
MAB_1963|M.abscessus_ATCC_1997      -----------------------