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M. vanbaalenii PYR-1 Mvan_5004 (-)

annotation: hypothetical protein Mvan_5004
coordinates: 5352121 - 5355240
length: 1039

GYAQFVGRVGALAVALGVGAATVALPGAAWAEPSDAASSSSADNTKAEDTAEDSTAADDARPDDAVDDEV
NSGEDHDEEAPQSEDGGDGSDEDGGQPEKKTRGSYGSNRSEGELTGEDADEARADREDTDTEADVDVVAP
EAEPTADEADDEADGGDPAEVAEPGVADDVAVEQPAEVSDDAPEPVESPISAPSSIVTALFAPKSWGDTA
PADPVESPLLWTLLAFARRQFGQPRTEIGDSGTPTGTTELVDPGAAAVPEPGEVTKGDPGIFTGTVRGQV
KATDPDGGWLTYSGSTSTEKGTVTVTPWGTFRYTPSATARHAAAADGASTEAKTDTFTVTVKDAAGNAVE
VPVTVDILARNADPFGARARADNPSLTTGTAIIRVSAYDFDRDPLDITGPLSTGKGELVDNGDGTFTYTP
TAAAREAASDPDAPDDARIDTLTFTISDGHGGIRTATVDVIVAAYAESSASTPGRAAGPVLVSSNGTIYQ
VTYDLDSTNNPIRTRVSILDEDGQVLKTTDVIPGYPVEQALPVVRPDGSLLVTTYKASSNTSTVSIVDGQ
GEVKTLGTVIGQPSAPMTVAPNGAVFFKTRQFASGSGDRLVRVSATGGLRVYQLGVAADSPSVAPDGSVY
IVSRSFGVTSVLAVGPGGNSRRVSLPLGADTVNDVVIGQDGRGYLTVERNVFGTKTTRVYTFTGTSNTVR
EIPGTPDGAKVITADGVYQYTYDESTGKSYISRITADTIETSDPIDGRVINPISVTPDGTVYVAVRNSAT
GTDSVAIISTSGEVTTVDIPGTIFPVLPSVSPAVTGDDANPNIGDNGYVAYQSGGVSYLAVVNPDGTIAR
TVTLPAGAVVATPVDFGPDGAAYQVIETRDEQGRVTSRAVLALSTDTVTPMLPGAPLQPNYPSIQFGPDG
SGVLITVETGQSPFEYHFLRFDQDGATIATADLSGFLQSAQQDYVFWQEGVVFGPDGTPYATLTGADQGV
WALTSTGPVKVLELDLGQGELVEPVKFGPDGTPYVTVSERVDGSYVTTVHTFTPVTML*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_5004--100% (1039)hypothetical protein Mvan_5004
M. vanbaalenii PYR-1Mvan_1720-5e-6327.82% (1071) YVTN beta-propeller repeat-containing protein
M. vanbaalenii PYR-1Mvan_1009-8e-5033.86% (505) putative outer membrane adhesin like proteiin

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0912-9e-0545.00% (60) hypothetical protein Mb0912
M. gilvum PYR-GCKMflv_1994-4e-8534.41% (741) hypothetical protein Mflv_1994
M. tuberculosis H37RvRv0888-9e-0545.00% (60) hypothetical protein Rv0888
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0628-3e-0623.85% (239) hypothetical protein MAB_0628
M. marinum MMMAR_3768rne1e-0729.75% (158) ribonuclease E Rne
M. avium 104MAV_3172-6e-0626.43% (140) prolipoprotein diacylglyceryl transferase
M. smegmatis MC2 155MSMEG_4365-3e-1725.71% (350) hypothetical protein MSMEG_4365
M. thermoresistible (build 8)TH_2316-7e-1035.09% (171) conserved hypothetical protein
M. ulcerans Agy99MUL_3715rne2e-0624.24% (165) ribonuclease E Rne

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_5004|M.vanbaalenii_PYR-1       ----------------------------MGYAQFVGRVGALAVALGVGAA
Mflv_1994|M.gilvum_PYR-GCK          ----------------------------MALDRYIGRVGALAVALGIGSA
Mb0912|M.bovis_AF2122/97            ----------------------------MDYAKRIGQVGALAVVLGVGAA
Rv0888|M.tuberculosis_H37Rv         ----------------------------MDYAKRIGQVGALAVVLGVGAA
MSMEG_4365|M.smegmatis_MC2_155      ----------------------------------MGRIGALAVALGIGAA
TH_2316|M.thermoresistible__bu      ----------------------------------VGRVGALAVALGVGVA
MMAR_3768|M.marinum_M               --------------MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTS
MUL_3715|M.ulcerans_Agy99           --------------MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTS
MAB_0628|M.abscessus_ATCC_1997      MPKQDRGAPPRPPWLPEEDEQRGFLRSLRRKKRNPDEGEPNDESLTHETE
MAV_3172|M.avium_104                ------------------------------MTKLLAYFPSPPQGVWHLGP
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       TVALPGAAWAEPSDAASSSSADNTKAEDTAEDSTAADDARPDDAVDDEVN
Mflv_1994|M.gilvum_PYR-GCK          VAAMPGQASAKPDADGGSG----------MSETSVSGPARAGSGTDATSR
Mb0912|M.bovis_AF2122/97            VTTHAIGSAAPTDPSSSST-----------DSPVDACSPLGGSASSLAAI
Rv0888|M.tuberculosis_H37Rv         VTTHAIGSAAPTDPSSSST-----------DSPVDACSPLGGSASSLAAI
MSMEG_4365|M.smegmatis_MC2_155      LTTG-TGVAWADDSGASGGSTS------SSSSASDS------SSSSAGGS
TH_2316|M.thermoresistible__bu      VATGGTAVAWAD-SGSTASSSS------SQDSSSKSNPAQTRSSAKSGIG
MMAR_3768|M.marinum_M               SRRVLDALSALDGRIRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEGQQA
MUL_3715|M.ulcerans_Agy99           SRRVLDALSALDGRIRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEDQQA
MAB_0628|M.abscessus_ATCC_1997      WPSAPKTAAQKPSAESVKLSGQGRPTLTSGDESADGDQPVSDLSKYYTPP
MAV_3172|M.avium_104                VPIRAYALFIIAGIVAALLIGD------RRWEARGGERGVIYDIALWTVP
                                                                   .                  

Mvan_5004|M.vanbaalenii_PYR-1       SGEDHD--------------------------------------------
Mflv_1994|M.gilvum_PYR-GCK          SGKPAQ--------------------------------------------
Mb0912|M.bovis_AF2122/97            PGASVP--------------------------------------------
Rv0888|M.tuberculosis_H37Rv         PGASVP--------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155      SGSASG--------------------------------------------
TH_2316|M.thermoresistible__bu      SGAGSGPGSRLDRPASRA-------------------------------P
MMAR_3768|M.marinum_M               PDAVAAEVPDAPGEPAEPDEPESRLMLETQETVQVVETWVERPHYMPLFV
MUL_3715|M.ulcerans_Agy99           PDAVAAEVPDAPGEPAEP---ESRLMLETQETVQVVETWVERPHYMPLFV
MAB_0628|M.abscessus_ATCC_1997      RRAEPADDSSSASEPIAVPG---------------------------PVA
MAV_3172|M.avium_104                FGLVGG--------------------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       -----EEAPQSEDGGDGSDEDGGQPEKKTRGSYGSNRSEGELTGEDADEA
Mflv_1994|M.gilvum_PYR-GCK          -----SERSAATKPSGGSDPPDRSPR------------------------
Mb0912|M.bovis_AF2122/97            -----QVGVRQVDPGSIPDD------------------------------
Rv0888|M.tuberculosis_H37Rv         -----QVGVRQVDPGSIPDD------------------------------
MSMEG_4365|M.smegmatis_MC2_155      ----GADAAKPRKPGVTKP------------RIQPTG-------------
TH_2316|M.thermoresistible__bu      LGGSGADSSATEQTGAVSSGTSAWRSAGMPAGTSLTG-------------
MMAR_3768|M.marinum_M               APQPISEPVAGDDADDESGDEGDDDEEQADRPANRRRRRGRRGRGRGRGE
MUL_3715|M.ulcerans_Agy99           APQPISEPVAGDDADDESGDEGDDDEEQADRPGNRRRRRGRRGRGRGRGE
MAB_0628|M.abscessus_ATCC_1997      ESDAQAPRIVRGPSADVAPEPQPTPQVEQLSSSVPVESSAMPEQEPEVPA
MAV_3172|M.avium_104                --------------------------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       RADREDTDTEADVDVVAPEAEPTADEADDEADGGDPAEVAEPGVADDVAV
Mflv_1994|M.gilvum_PYR-GCK          ---------EVAVTEETTSGETADDEAEPVEETRDTVEIVPP--------
Mb0912|M.bovis_AF2122/97            -------LLNALIDFLAAVRNGLVPIIENRTPVANPQQVSVP--------
Rv0888|M.tuberculosis_H37Rv         -------LLNALIDFLAAVRNGLVPIIENRTPVANPQQVSVP--------
MSMEG_4365|M.smegmatis_MC2_155      -------KIAESLKKTAKAVEGAVADAHKRAQQSAAQQAEKRAER-----
TH_2316|M.thermoresistible__bu      -------RLADSVRDAVKPWRPATTRSTDPTPVETPAEANPEAQP-----
MMAR_3768|M.marinum_M               QGANDGQDQPGDDGDEAPQKTGGNSTSSDDTEAQDGADSEESDNGDDDNG
MUL_3715|M.ulcerans_Agy99           QGANDGQDQPGDDGDEAPQKAGGNSTSSDDSEAQDGADSEESDNGDDDNG
MAB_0628|M.abscessus_ATCC_1997      SNPVVESALAVTGEPEPPLQAAATPEVTRPVVPRPEQPVTGPERVVVDSG
MAV_3172|M.avium_104                -------RLYHLATDWRTYWGPGGAGFGAAVRIWDGG-------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       EQPAEVSDDAPEPVESPISAPSSIVTALFAPKSWGDTAPADPVESPLLWT
Mflv_1994|M.gilvum_PYR-GCK          --------------TEPVTPASAVET---------EDEPDSPASSSLLWF
Mb0912|M.bovis_AF2122/97            -----------------------------------EGGTVGPVR------
Rv0888|M.tuberculosis_H37Rv         -----------------------------------EGGTVGPVR------
MSMEG_4365|M.smegmatis_MC2_155      -----------------------------------RAKLRAQIRPGKDTD
TH_2316|M.thermoresistible__bu      -----------------------------------DAHAGSPGESTAPET
MMAR_3768|M.marinum_M               SADG----------ANRRRRRRRRRKSGAGDDGDEGPAPDDPPNTVVHER
MUL_3715|M.ulcerans_Agy99           SADG----------ASRRRRRRRRRKSGAGDDGDEGPAPDDPPNTVVHER
MAB_0628|M.abscessus_ATCC_1997      SADPFSRFSLLEAQLRQMSLDESITDDELERHRRHSAPEAEPAAAPAAAL
MAV_3172|M.avium_104                --------------------------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       LLAFARRQFGQPRTEIGDSGTPTGTTELVDPGAAAVPEPGEVTKGDPGIF
Mflv_1994|M.gilvum_PYR-GCK          LGAAGRRQTDQQAGPDRDAASQTAAQAEAPIAATPVP-------------
Mb0912|M.bovis_AF2122/97            ----------------FDACDPDGNRMTFAVRERGAPG------------
Rv0888|M.tuberculosis_H37Rv         ----------------FDACDPDGNRMTFAVRERGAPG------------
MSMEG_4365|M.smegmatis_MC2_155      KQAPEKQ---------AGNEAKNAAQPATKTQRQLP--------------
TH_2316|M.thermoresistible__bu      QPAPSSRGIRSMTAVLPDTESTNTESTNTESTVQHDDS------------
MMAR_3768|M.marinum_M               APRSGGKSGNSDSGDDSGGNEIKGIDGSTRLEAKRQRRR-----------
MUL_3715|M.ulcerans_Agy99           APRSGDKSGNSDSGDDSGGNEIKGIDGSTRLEAKRQRRR-----------
MAB_0628|M.abscessus_ATCC_1997      SFTPPEVAASTPDGPTEALGEAQAAVESPSEEPAPTPTLG----------
MAV_3172|M.avium_104                ----------------------LGIWGAVALG------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       TGTVRGQVKATDPDGGWLTYSGSTSTEKGTVTVTPWGTFRYTPSATARHA
Mflv_1994|M.gilvum_PYR-GCK          --------------------------------------------------
Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155      --------------------------------------------------
TH_2316|M.thermoresistible__bu      --------------------------------------------------
MMAR_3768|M.marinum_M               --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           --------------------------------------------------
MAB_0628|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       AAADGASTEAKTDTFTVTVKDAAGNAVEVPVTVDILARNADPFGARARAD
Mflv_1994|M.gilvum_PYR-GCK          --------------------------------------------------
Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155      --------------------------------------------------
TH_2316|M.thermoresistible__bu      --------------------------------------------------
MMAR_3768|M.marinum_M               --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           --------------------------------------------------
MAB_0628|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       NPSLTTGTAIIRVSAYDFDRDPLDITGPLSTGKGELVDNGDGTFTYTPTA
Mflv_1994|M.gilvum_PYR-GCK          --------------------------------------------------
Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155      --------------------------------------------------
TH_2316|M.thermoresistible__bu      --------------------------------------------------
MMAR_3768|M.marinum_M               --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           --------------------------------------------------
MAB_0628|M.abscessus_ATCC_1997      ---------------------------------------------FTAPE
MAV_3172|M.avium_104                --------------------------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       AAREAASDPDAPDDARIDTLTFTISDGHGGIRTATVDVIVAAYAESSAST
Mflv_1994|M.gilvum_PYR-GCK          --------------------------------------------------
Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155      --------------------------------------------------
TH_2316|M.thermoresistible__bu      ---------------------------------------------ERRSS
MMAR_3768|M.marinum_M               ---------DGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPH
MUL_3715|M.ulcerans_Agy99           ---------DGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPH
MAB_0628|M.abscessus_ATCC_1997      PEDDVPAVDQEAVGARGEQEAAVTAVPPIADRPEPNSAGNEPATDQTSDF
MAV_3172|M.avium_104                --------------------------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       PGRAAGPVLVSSNGTIYQVTYDLDSTNNPIRTRVSILDE---DGQVLKTT
Mflv_1994|M.gilvum_PYR-GCK          -GDASASPIIGVDGTVYQVTRTSSAGG--QFSTVTILDN---TGQIVSSG
Mb0912|M.bovis_AF2122/97            -GPQHGIVTVDQRTASFIYTADPGFVG---TDTFSVNVS---DDTSLHVH
Rv0888|M.tuberculosis_H37Rv         -GPQHGIVTVDQRTASFIYTADPGFVG---TDTFSVNVS---DDTSLHVH
MSMEG_4365|M.smegmatis_MC2_155      -AAPAVKVPDVITSVRARSDEVAREITTGVTGIRTAIEN---AAPRIALP
TH_2316|M.thermoresistible__bu      LRSTAASVPELSTPVRLADATAVRALAERLTERRSVTLE---SVR--AFT
MMAR_3768|M.marinum_M               PGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFV
MUL_3715|M.ulcerans_Agy99           PGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFV
MAB_0628|M.abscessus_ATCC_1997      SSPKPEESADSGDSLAPQPPAVEQPTAAEVVEPPESAPAAGGGDADARAA
MAV_3172|M.avium_104                --AVGAWIGCRRHGIPLPAFADALAPGIILAQAIGRLGN-------YFNQ
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       DVIPGYPVEQALPVVRPDGSLLVTTYKASSNTSTVSIVDGQGEVKTLGTV
Mflv_1994|M.gilvum_PYR-GCK          EVRG----TVMDAVARPDGTLVVFSRRFIS--TTVSTVSSDGTVTPIANL
Mb0912|M.bovis_AF2122/97            GLAG-----------------------------YLGPFHGHDDVATVTVF
Rv0888|M.tuberculosis_H37Rv         GLAG-----------------------------YLGPFHGHDDVATVTVF
MSMEG_4365|M.smegmatis_MC2_155      DLRP----------------TTNL-------ARPVTPVALKAAQPVQ---
TH_2316|M.thermoresistible__bu      DVAA----------------TTALTSAASVAAATVEPVALITAAPEATPA
MMAR_3768|M.marinum_M               DIGRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYIVVQVSKDPVGH
MUL_3715|M.ulcerans_Agy99           DIGRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYIVVQVSKDPVGH
MAB_0628|M.abscessus_ATCC_1997      ALLQRIEARRAELDEELAAHDAADAQARAFEPEPAPFVPMVAPWASVPEP
MAV_3172|M.avium_104                ELYG--------------------------RETTLPWGLEIFYRRDPSGY
                                     :                                                

Mvan_5004|M.vanbaalenii_PYR-1       IGQPSAPMTVAPNGAVFFKTRQFASGSGDRLVRVSATGGLRVYQLG----
Mflv_1994|M.gilvum_PYR-GCK          LGTPLNPPRVGPDGALYFG-----AGLPDLLSPVGANVGYRTYRISPRNT
Mb0912|M.bovis_AF2122/97            VGNTPTDTISGDFSMLTYN----IAGLPFPLSSAILPRFFYTKEIG----
Rv0888|M.tuberculosis_H37Rv         VGNTPTDTISGDFSMLTYN----IAGLPFPLSSAILPRFFYTKEIG----
MSMEG_4365|M.smegmatis_MC2_155      VSPPRPTITGLVRGLLTAAAGFSPRAATAPVAPAPSPAAWALLAFARREF
TH_2316|M.thermoresistible__bu      VDAEQPAAPRLVTGLL-AAVGLAPFTANSPLAPTQSTPLLALLGWARRET
MMAR_3768|M.marinum_M               KGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSD
MUL_3715|M.ulcerans_Agy99           KGARLTTQVSLAGRYLVYVAGASSTGISRKLPDTERQRLKEILREVVPSD
MAB_0628|M.abscessus_ATCC_1997      VRSPAPEAAAPANDADETADTATSSSGAAELEGFAPLVDEDIVISAPAVY
MAV_3172|M.avium_104                IDPHSLDGVSTGQVALVVQPTFLYELLWNLLIFVALLYADRRLTLG----
                                                                  :                   

Mvan_5004|M.vanbaalenii_PYR-1       ----VAADSPSVAPDGSVYIVSRSFGVTSVLAVGPGGNSRRVSLPLGADT
Mflv_1994|M.gilvum_PYR-GCK          VRAFAFDTDVAIADDGTAYLVSRRYGISVLRVIPTAGLGRTTLLPLGTDP
Mb0912|M.bovis_AF2122/97            ----KRLNAYYVANVQEDFAYHQFLIKKSKMPSQTPPEPPTLLWPIGVPF
Rv0888|M.tuberculosis_H37Rv         ----KRLNAYYVANVQEDFAYHQFLIKKSKMPSQTPPEPPTLLWPIGVPF
MSMEG_4365|M.smegmatis_MC2_155      ERAFTPGAATALAAPAITTSAVTSAAVVNPLPGRLD--SVPVGWVTGVSN
TH_2316|M.thermoresistible__bu      DRAYTQQARSLVTA---RPAVVSTAAVVDPLPADLIGETERIGRITGPG-
MMAR_3768|M.marinum_M               AGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKAVEIKQKAAGAAVALY
MUL_3715|M.ulcerans_Agy99           AGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKAVEIKQKAAGAAVALY
MAB_0628|M.abscessus_ATCC_1997      EEAPADAGLDDVILESELPDEAEAPAARAVDPEPAGETADVAPESAAPES
MAV_3172|M.avium_104                -----HGRLFALYVAGYCVGRFCVELLRDDTATHIAGIRINSFTSTFVFI
                                               :                                      

Mvan_5004|M.vanbaalenii_PYR-1       VNDVVIGQDGRGYLTVERNVFGTKTTR--------VYTFTGTSNTVREIP
Mflv_1994|M.gilvum_PYR-GCK          S-APVLGPDGTAHVTAGVTWFGSPQTR--------VYTATGDSIAAHTVA
Mb0912|M.bovis_AF2122/97            SDGLNTLSEFKVQRLDRQTWYECTSDN--------CLTLKGFTYSQMRLP
Rv0888|M.tuberculosis_H37Rv         SDGLNTLSEFKVQRLDRQTWYECTSDN--------CLTLKGFTYSQMRLP
MSMEG_4365|M.smegmatis_MC2_155      PSGNWPQTNNTAGFDIWGTDLGIMWDGGEWNGQRFVHTAFGDTFSGPNMS
TH_2316|M.thermoresistible__bu      ------ITDGPNRLNIYGTDLGIMWDMGEWRGQRAVHVVFGDTFSGPNMS
MMAR_3768|M.marinum_M               EEPDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVSKLSKY
MUL_3715|M.ulcerans_Agy99           EEPDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVSKLSKY
MAB_0628|M.abscessus_ATCC_1997      PAQTPTADRQEESISVVAPEPGSAEPSPWQNRSAVEVAATGEPQATPAYY
MAV_3172|M.avium_104                GAVVYLMAAPKGREDPES--------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       GTPDGAKVITADGVYQYTYDE--S----TGKSYISRITADTIETSDPIDG
Mflv_1994|M.gilvum_PYR-GCK          GLPAGAVVG-ADGVYLATFVE--PGSEGPGTSYVSRLTAGGVGTSGLIEG
Mb0912|M.bovis_AF2122/97            GG------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         GG------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155      GWWRSNVLLISTDNVLSDGLG--LVQTGTAYQFIPASGRNLFGLFGGSEV
TH_2316|M.thermoresistible__bu      GDWISNAIMISTSRTLYENPAGFLEQTGPAFQFIP--GGQLLSWFFPAEV
MMAR_3768|M.marinum_M               EPAVGSEGQVGPDVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTV
MUL_3715|M.ulcerans_Agy99           EPAVGSEGQVGPDVFAVHRIDEHLAKAMDRKVWLPSGGTLVIDRTEAMTV
MAB_0628|M.abscessus_ATCC_1997      VPPAASPQPDTQAPPAQEPAAQVPPGWSPPQPYPGQWPQPAPAAPQPYGG
MAV_3172|M.avium_104                --------------------------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       RVINPISVTPDGTVYVAVRNSATGTDSVAIISTS----------------
Mflv_1994|M.gilvum_PYR-GCK          -RIAEFQVTAEGTVFAPIDG-AGAETPVAVIDRD----------------
Mb0912|M.bovis_AF2122/97            ---------DTVDVYNLHTNTGGGPTTNANLAQV----------------
Rv0888|M.tuberculosis_H37Rv         ---------DTVDVYNLHTNTGGGPTTNANLAQV----------------
MSMEG_4365|M.smegmatis_MC2_155      TVIPTAGVQIDGTQYVNYMSVRSWDTPGRWTTNF----------------
TH_2316|M.thermoresistible__bu      TVIPTAGVHANGTQYVNYMSVRQWGVPGSWTTNF----------------
MMAR_3768|M.marinum_M               VDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLRLRD------------
MUL_3715|M.ulcerans_Agy99           VDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLRLRD------------
MAB_0628|M.abscessus_ATCC_1997      QQFPSQPPPQPTSVQGQWQWVPQQPQGPQSAAQQEPPAGYPPPPQGGTPP
MAV_3172|M.avium_104                ---------LRGNQYVEEEPAEPEPATVAATTEA----------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       ------------GEVTTVDIPGTIFPVLPSVSPAV--TGDDANPNIGDNG
Mflv_1994|M.gilvum_PYR-GCK          ------------GTVHTVLLPGTLVVGRRAIR-------DGGTYNVEDVG
Mb0912|M.bovis_AF2122/97            ------------ANYIQQNSAGRAVIVTGDFN----------------AR
Rv0888|M.tuberculosis_H37Rv         ------------ANYIQQNSAGRAVIVTGDFN----------------AR
MSMEG_4365|M.smegmatis_MC2_155      ------------SAISVYDPSTDTWVLAPSTIRSAGWFRSSTLYVPGSQN
TH_2316|M.thermoresistible__bu      ------------SAISRYDQATDTWVTVPSSVRSAGWLRSSTPYRAGDQN
MMAR_3768|M.marinum_M               -----------IGGIVVIDFIDMVLESNRDLVLRRLTEALARDRTRHQVS
MUL_3715|M.ulcerans_Agy99           -----------IGGIVVIDFIDMVLESNRDLVLRRLTEALARDRTRHQVS
MAB_0628|M.abscessus_ATCC_1997      ANYRAPQAYRMPPSLDEAEVINRGRYAPRSGWRKAVHRSTGGRVNPGDSR
MAV_3172|M.avium_104                -------------ATEGVAAPADGAEAAG-----------------ADAT
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       YVAYQSGGVSYLAVVNPDGTIARTVTLPAGA------------------V
Mflv_1994|M.gilvum_PYR-GCK          YVNYATGGREYVAVLSADGTVARTIELPEGA------------------T
Mb0912|M.bovis_AF2122/97            YSDDQSALLQFAQVNGLTDAWVQVEHGPTTP------------------P
Rv0888|M.tuberculosis_H37Rv         YSDDQSALLQFAQVNGLTDAWVQVEHGPTTP------------------P
MSMEG_4365|M.smegmatis_MC2_155      FQQAAYVLQPEDQVGEDGIRYLYAFGTPSGR------------------A
TH_2316|M.thermoresistible__bu      FQQMAYVLQPVDQVGEDGVRYVYAFGTPSGR------------------Q
MMAR_3768|M.marinum_M               EVTSLGLVQLTRKRLGTGLVEAFSTSCPHCS------------------G
MUL_3715|M.ulcerans_Agy99           EVTSLGLVQLTRKRLGTGLIEAFSTSCPHCS------------------G
MAB_0628|M.abscessus_ATCC_1997      KDRERDLLLASIRQPILGDYRIAVLSIKGGVGKTTTTLGLGSAFATIRTD
MAV_3172|M.avium_104                AQRPEESAEPDVEKPESEETEAEAAEEPESE-------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       VATPVDFGPDGAAYQVIETRDEQGRVTSRAVLALSTDTVTPMLPGAPLQP
Mflv_1994|M.gilvum_PYR-GCK          GGS-VFYSPDGAAFEMLEYRDAQGQTTFRQILALASTTYTDKVPGGRFTY
Mb0912|M.bovis_AF2122/97            FAPTCMVGNECELLDKIFYRSGQG-------VTLQAVSYGNEAPKFFNSK
Rv0888|M.tuberculosis_H37Rv         FAPTCMVGNECELLDKIFYRSGQG-------VTLQAVSYGNEAPKFFNSK
MSMEG_4365|M.smegmatis_MC2_155      GSAYLSRVPEDAVTDLSKYEYWDGNRWVTGNAAVAAPVIGDSTRSTGLFG
TH_2316|M.thermoresistible__bu      GSVHLSRVPEEHITDVSKYEYWDGNAWVS-SAAHAAPIIGESTRSAGLFG
MMAR_3768|M.marinum_M               RGILLHADPVDSAPTTGRKADSGGRRNRRSKKNRAEEPSEKEAVAKVPTH
MUL_3715|M.ulcerans_Agy99           RGILLHADPVDSAPTTGRKADSGGRRNRRSKKNRAEEPSEKEAVAKVPTY
MAB_0628|M.abscessus_ATCC_1997      RIIAVDANPDRGTLAERVRDHSTQSTVRDLLNDQNIRSYADVRNHTRMAT
MAV_3172|M.avium_104                ---ETEAAEEPGEPEAEEPEEPEAEEPEEPETEEPEADSDEEPE------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       N---YPSIQFGPDGSGVLITVETGQSP---FEYHFLRFDQDGATIATADL
Mflv_1994|M.gilvum_PYR-GCK          V---RDTVVFGPDGVGYLLTGSVSTQIGASQDLDVLGFNAAGETVSRAGG
Mb0912|M.bovis_AF2122/97            G---EPLSDHSP---------------------AVVGFHYVADNVAVR--
Rv0888|M.tuberculosis_H37Rv         G---EPLSDHSP---------------------AVVGFHYVADNVAVR--
MSMEG_4365|M.smegmatis_MC2_155      F---IVDWANDP---------------------NVLGGYLGGLVGAKTGG
TH_2316|M.thermoresistible__bu      F---IIDWANDP---------------------NVFGGYLGGLFGAKTGG
MMAR_3768|M.marinum_M               APGEHPMFKAMAASSSSEAEHGDGEVEESGEELTAAVDDQTAVQVALDLG
MUL_3715|M.ulcerans_Agy99           APGEHPMFKAMAASSSSEAEHGDGEVEESGEELTAAVDDQTAVQVALDLG
MAB_0628|M.abscessus_ATCC_1997      SRLEVLASEQDPAVSEAFGEIDYRNTIDILQRYYNIILTDCGTGIMHSAM
MAV_3172|M.avium_104                --------------------------------------EESGEAPEQPVA
                                                                             .        

Mvan_5004|M.vanbaalenii_PYR-1       SGFLQSAQQDYVFWQEGVVFGPDGTPYATLTG--ADQGVW----ALTSTG
Mflv_1994|M.gilvum_PYR-GCK          LTNPVTTYENNPYRTV-LAFGRDGTAYVTLYFTPDDPGVY----AVTATG
Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155      NVSELSVQYNEYLGKYVVLYGDG-NNNIQMRIADRPEGPWSDPIELASSA
TH_2316|M.thermoresistible__bu      NVGEMSVQYNEYLGKYVILYGNGRTNNIEMRIADSPEGPWSDPIILATPQ
MMAR_3768|M.marinum_M               QTDETEETDETDETDETDDFDDDSDDSDDSDEDDDSDETNDTDVDAGEDE
MUL_3715|M.ulcerans_Agy99           ---ETEESEETDGTDETDDFDDDSDDSDDSDEDDDTDETNDTDVDADEDE
MAB_0628|M.abscessus_ATCC_1997      AGVLDLAHTIVLVSSPAMDSARSASATLDWLMQHGYSSLVREAHVVLSAS
MAV_3172|M.avium_104                EEPEPAPQQPETKRRWGARLRDRLSGR-----------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       PVKVLE-----------------------------------LDLGQGELV
Mflv_1994|M.gilvum_PYR-GCK          ARKVVD-----------------------------------LEYVQYRQG
Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155      DYPGLY-----------------------------------APMIHPWSG
TH_2316|M.thermoresistible__bu      QYPGLY-----------------------------------APMIHPWSG
MMAR_3768|M.marinum_M               DTDDDSDEDSDDDSDEDEDTEDDELDDDLDEDDLDDDLDEDDDDLDDELD
MUL_3715|M.ulcerans_Agy99           DTDDDS--------DEDEDTEDD---------------DELDDDLDDELD
MAB_0628|M.abscessus_ATCC_1997      RPGSAG-----------------------IKLDKVYEHFQARCRSIHMIP
MAV_3172|M.avium_104                --------------------------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       EPVKFGPDGTPYVTVSERVDG--SYVTTVHTFTPVTML------------
Mflv_1994|M.gilvum_PYR-GCK          FPPTFGLDGTGYVTSAELLSGDADGIALVTVFSPVTDL------------
Mb0912|M.bovis_AF2122/97            --------------------------------------------------
Rv0888|M.tuberculosis_H37Rv         --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155      TGMLEDDNGDPDVNNLYWNMSLWGDYNVVLMQTDLSGLKTVAV-------
TH_2316|M.thermoresistible__bu      TGYLLDENGDPDPESLYWNMSMWGPYNVYLMQTDLSSLVEV---------
MMAR_3768|M.marinum_M               DDDSDSDDEDGESELTEPAAGRPAALEVTTIAERPRRRRAAGRPAGPPIH
MUL_3715|M.ulcerans_Agy99           DDDSDSDDEDSESELTEPAAGRPAALEVTTIAERPRRRRAAGRPAGPPIH
MAB_0628|M.abscessus_ATCC_1997      FDPHLAEGADVDFNLLNADTNAAYLKLAGAISESFPRLRVRGDEQR----
MAV_3172|M.avium_104                --------------------------------------------------
                                                                                      

Mvan_5004|M.vanbaalenii_PYR-1       --
Mflv_1994|M.gilvum_PYR-GCK          --
Mb0912|M.bovis_AF2122/97            --
Rv0888|M.tuberculosis_H37Rv         --
MSMEG_4365|M.smegmatis_MC2_155      --
TH_2316|M.thermoresistible__bu      --
MMAR_3768|M.marinum_M               LG
MUL_3715|M.ulcerans_Agy99           LG
MAB_0628|M.abscessus_ATCC_1997      --
MAV_3172|M.avium_104                --