For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TKLLAYFPSPPQGVWHLGPVPIRAYALFIIAGIVAALLIGDRRWEARGGERGVIYDIALWTVPFGLVGGR LYHLATDWRTYWGPGGAGFGAAVRIWDGGLGIWGAVALGAVGAWIGCRRHGIPLPAFADALAPGIILAQA IGRLGNYFNQELYGRETTLPWGLEIFYRRDPSGYIDPHSLDGVSTGQVALVVQPTFLYELLWNLLIFVAL LYADRRLTLGHGRLFALYVAGYCVGRFCVELLRDDTATHIAGIRINSFTSTFVFIGAVVYLMAAPKGRED PESLRGNQYVEEEPAEPEPATVAATTEAATEGVAAPADGAEAAGADATAQRPEESAEPDVEKPESEETEA EAAEEPESEETEAAEEPGEPEAEEPEEPEAEEPEEPETEEPEADSDEEPEEESGEAPEQPVAEEPEPAPQ QPETKRRWGARLRDRLSGR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_3172 | - | - | 100% (440) | prolipoprotein diacylglyceryl transferase |
M. avium 104 | MAV_4817 | - | 7e-08 | 30.86% (162) | ferredoxin, 4Fe-4S |
M. avium 104 | MAV_0048 | - | 7e-08 | 31.25% (160) | hypothetical protein MAV_0048 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1640 | lgt | 1e-152 | 60.13% (454) | prolipoprotein diacylglyceryl transferase |
M. gilvum PYR-GCK | Mflv_3597 | - | 1e-137 | 56.86% (459) | prolipoprotein diacylglyceryl transferase |
M. tuberculosis H37Rv | Rv1614 | lgt | 1e-152 | 60.13% (454) | prolipoprotein diacylglyceryl transferase |
M. leprae Br4923 | MLBr_01274 | - | 1e-152 | 78.95% (323) | putative prolipoprotein diacylglyceryl transferase |
M. abscessus ATCC 19977 | MAB_2642c | - | 1e-135 | 69.14% (337) | prolipoprotein diacylglyceryl transferase |
M. marinum M | MMAR_2416 | lgt | 1e-165 | 67.20% (439) | prolipoprotein diacylglyceryl transferases Lgt |
M. smegmatis MC2 155 | MSMEG_3222 | - | 1e-142 | 59.59% (443) | prolipoprotein diacylglyceryl transferase |
M. thermoresistible (build 8) | TH_1073 | lgt | 1e-139 | 72.64% (329) | Possible prolipoprotein diacylglyceryl transferases Lgt |
M. ulcerans Agy99 | MUL_3715 | rne | 2e-06 | 21.33% (150) | ribonuclease E Rne |
M. vanbaalenii PYR-1 | Mvan_2819 | - | 1e-146 | 61.11% (450) | prolipoprotein diacylglyceryl transferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb1640|M.bovis_AF2122/97 -MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITG---------------- Rv1614|M.tuberculosis_H37Rv -MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITG---------------- MLBr_01274|M.leprae_Br4923 MTRMLPGYFPSPPRGVWHLGPLPIRAYALLIILG---------------- MMAR_2416|M.marinum_M MTATVLAYFPSPPRGVWHLGPLPIRAYAFFIIIG---------------- MAV_3172|M.avium_104 -MTKLLAYFPSPPQGVWHLGPVPIRAYALFIIAG---------------- MAB_2642c|M.abscessus_ATCC_199 MTVVNLAYIPSPPQGVWHLGPIPIRAYALCIIAG---------------- MSMEG_3222|M.smegmatis_MC2_155 MTTTVLAYLPSPSQGVWHLGPVPIRAYALCIIVG---------------- TH_1073|M.thermoresistible__bu -VTTTLAYIPSPAQGVWQLGPIPIRAYALCIIAG---------------- Mflv_3597|M.gilvum_PYR-GCK MTTTVLAYIPSPPQGVWYLGPFPLRAYALCIIVG---------------- Mvan_2819|M.vanbaalenii_PYR-1 MTTTVLAYIPSPSQGVWHLGPFPVRAYALFIIVG---------------- MUL_3715|M.ulcerans_Agy99 MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR . *. * :*.::. * Mb1640|M.bovis_AF2122/97 --------------IIVALLIGDRRLTARGGERGMTYDIALWAVPFG--- Rv1614|M.tuberculosis_H37Rv --------------IIVALLIGDRRLTARGGERGMTYDIALWAVPFG--- MLBr_01274|M.leprae_Br4923 --------------IVAALVVGGRCWEARGGERDVTYDIALWAVPFG--- MMAR_2416|M.marinum_M --------------IVMGLMIGDRRFAARGGERGVIYDIALWMVPFG--- MAV_3172|M.avium_104 --------------IVAALLIGDRRWEARGGERGVIYDIALWTVPFG--- MAB_2642c|M.abscessus_ATCC_199 --------------IVAALIIGDRRWEQRGGERGVIYDIALWAVPFG--- MSMEG_3222|M.smegmatis_MC2_155 --------------IVAALVIGDRRWQARGGEPGVIYDIALWAVPFG--- TH_1073|M.thermoresistible__bu --------------IVVALVLGDRRWAARGGERGVIYDIALWAVPFG--- Mflv_3597|M.gilvum_PYR-GCK --------------IVAALVIGDRRWVARGGEPGVIYDIALWAVPFG--- Mvan_2819|M.vanbaalenii_PYR-1 --------------IIAALVIGDRRWVARGGESGVIYDIALWAVPFG--- MUL_3715|M.ulcerans_Agy99 IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEDQQAPDAVAAEVPDAPGE : *: :. * * . ** . Mb1640|M.bovis_AF2122/97 ---------LIGGRLYHLATDWRT-------------------------- Rv1614|M.tuberculosis_H37Rv ---------LIGGRLYHLATDWRT-------------------------- MLBr_01274|M.leprae_Br4923 ---------LVGGRLYHLATDWRT-------------------------- MMAR_2416|M.marinum_M ---------LIGGRLYHLSTDWQT-------------------------- MAV_3172|M.avium_104 ---------LVGGRLYHLATDWRT-------------------------- MAB_2642c|M.abscessus_ATCC_199 ---------LVGGRLYHVMTDWQT-------------------------- MSMEG_3222|M.smegmatis_MC2_155 ---------LAGGRIYHVITDWKT-------------------------- TH_1073|M.thermoresistible__bu ---------LIGGRVYHVLTDWRT-------------------------- Mflv_3597|M.gilvum_PYR-GCK ---------LIGGRLYHVITDWPT-------------------------- Mvan_2819|M.vanbaalenii_PYR-1 ---------LIGGRLYHVITDWPT-------------------------- MUL_3715|M.ulcerans_Agy99 PAEPESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDADDE * . :: * Mb1640|M.bovis_AF2122/97 --------------------YFGDGGAGLAAALRIWDGGLGIWG------ Rv1614|M.tuberculosis_H37Rv --------------------YFGDGGAGLAAALRIWDGGLGIWG------ MLBr_01274|M.leprae_Br4923 --------------------YFGQNGAGLGAALRIWDGGLGIWG------ MMAR_2416|M.marinum_M --------------------YFGEGGAGLGAALRIWDGGLGIWG------ MAV_3172|M.avium_104 --------------------YWGPGGAGFGAAVRIWDGGLGIWG------ MAB_2642c|M.abscessus_ATCC_199 --------------------YFGAHGKGIGKAIAVWEGGLGIWG------ MSMEG_3222|M.smegmatis_MC2_155 --------------------YFGPTGKGFGAALQIWEGGLGIWG------ TH_1073|M.thermoresistible__bu --------------------YFGPDGAGFVAALRIWDGGLGIWG------ Mflv_3597|M.gilvum_PYR-GCK --------------------YFGDGGAGPAAALRIWDGGLGIWG------ Mvan_2819|M.vanbaalenii_PYR-1 --------------------YFGEGGAGPAAALRIWDGGLGIWG------ MUL_3715|M.ulcerans_Agy99 SGDEGDDDEEQADRPGNRRRRRGRRGRGRGRGEQGANDGQDQPGDDGDEA * * * . :.* . * Mb1640|M.bovis_AF2122/97 -----------------------------AVTLGVMGAWIGCRRCGIPLP Rv1614|M.tuberculosis_H37Rv -----------------------------AVTLGVMGAWIGCRRCGIPLP MLBr_01274|M.leprae_Br4923 -----------------------------AVALGCVGAWLGCRRHRIPLP MMAR_2416|M.marinum_M -----------------------------AVTLGTVGAWIGCRRRGIPLP MAV_3172|M.avium_104 -----------------------------AVALGAVGAWIGCRRHGIPLP MAB_2642c|M.abscessus_ATCC_199 -----------------------------AVALGGVGAWIACRRRGIPLP MSMEG_3222|M.smegmatis_MC2_155 -----------------------------AVAFGAVGAWIACRLRGIPLP TH_1073|M.thermoresistible__bu -----------------------------AVALGGVGAWIACRRHGIPLP Mflv_3597|M.gilvum_PYR-GCK -----------------------------AVALGAVGAWIACRRRGIPLP Mvan_2819|M.vanbaalenii_PYR-1 -----------------------------AVALGGIGAWIACRRRGIPLP MUL_3715|M.ulcerans_Agy99 PQKAGGNSTSSDDSEAQDGADSEESDNGDDDNGSADGASRRRRRRRRRKS . ** * . Mb1640|M.bovis_AF2122/97 VLLDAVAPG--------VVLAQAIGRLGNYFNQELYGRETTMPWGLEIFY Rv1614|M.tuberculosis_H37Rv VLLDAVAPG--------VVLAQAIGRLGNYFNQELYGRETTMPWGLEIFY MLBr_01274|M.leprae_Br4923 AFGDALAPG--------IILAQAIGRLGNYFNQELYGRETTMPWGLEVFY MMAR_2416|M.marinum_M AFLDAVAPG--------VVMGQAIGRLGNYFNQELYGRETTVPWGLEIFY MAV_3172|M.avium_104 AFADALAPG--------IILAQAIGRLGNYFNQELYGRETTLPWGLEIFY MAB_2642c|M.abscessus_ATCC_199 AFADAIAPG--------IVLAQAIGRLGNYFNQELTGGPTTLPWGLELFY MSMEG_3222|M.smegmatis_MC2_155 AFGDAIAPG--------IILAQGIGRLGNYFNQELYGRPTDVPWGLEIYE TH_1073|M.thermoresistible__bu AFGDAIAPG--------IVLAQAIGRLGNYFNQELYGRPTTLPWGLEIYE Mflv_3597|M.gilvum_PYR-GCK AFGDAIAPG--------IVLAQAIGRLGNYFNQELYGRETTVPWGLEIYE Mvan_2819|M.vanbaalenii_PYR-1 AFGDAIAPG--------IVLAQAIGRLGNYFNQELFGRETTVPWGLEIYE MUL_3715|M.ulcerans_Agy99 GAGDDGDEGPAPDDPPNTVVHERAPRSGDKSGNSDSGDDSGGNE-IKGID * * :: : * *: .:. * : :: Mb1640|M.bovis_AF2122/97 RRDPSGFDVPNSLDGVSTGQVAFVVQPTFLYELIWNVLVFVALIYIDRRF Rv1614|M.tuberculosis_H37Rv RRDPSGFDVPNSLDGVSTGQVAFVVQPTFLYELIWNVLVFVALIYIDRRF MLBr_01274|M.leprae_Br4923 RRDPAGYMDPHSLDGVSTGQLAFVVQPTFLYELIWNVLVFFALIYVDRWF MMAR_2416|M.marinum_M RRDPSGFVDVHSLDGVSTGQVAVVVQPTFLYELIWNLLVFAALIYLDRRF MAV_3172|M.avium_104 RRDPSGYIDPHSLDGVSTGQVALVVQPTFLYELLWNLLIFVALLYADRRL MAB_2642c|M.abscessus_ATCC_199 RRSADGTVDVLNLNGVSTGEVAQVVHPTFLYELLWNVLVFVLLIVVDRRF MSMEG_3222|M.smegmatis_MC2_155 RLNKFGQSD--QLNGVSTGQVTAVVHPTFLYELIWNIAVFGFLIWVDRKF TH_1073|M.thermoresistible__bu RRNASGALD--PLNGTSTGELLAVVHPTFLYEMLWNVLVFVVLIWADRRF Mflv_3597|M.gilvum_PYR-GCK RRNSAGVLD--SLNGISTGELIGVVHPTFLYELLWNLLVFAVLILVDRRF Mvan_2819|M.vanbaalenii_PYR-1 RVNAAGVPD--SLNGVSTGELIQVVHPTFLYELLWNLLVFAVLILVDRRF MUL_3715|M.ulcerans_Agy99 GSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRT :* .:*. * . : : :: Mb1640|M.bovis_AF2122/97 IIGHGRLFGFYVAFYCAGRFCVELLRDDPATLIAG--------IRINSFT Rv1614|M.tuberculosis_H37Rv IIGHGRLFGFYVAFYCAGRFCVELLRDDPATLIAG--------IRINSFT MLBr_01274|M.leprae_Br4923 TLGHGRLFATYVAAYCIGRFCVELLRDDAATHIAG--------IRINSFT MMAR_2416|M.marinum_M TIGHGRLFASYVALYCVGRFCVELLRDDTATHIAG--------IRINSFT MAV_3172|M.avium_104 TLGHGRLFALYVAGYCVGRFCVELLRDDTATHIAG--------IRINSFT MAB_2642c|M.abscessus_ATCC_199 KIGHGRLFAMYVAAYCVGRFCVELMRVDPATQFGG--------IRVNSFT MSMEG_3222|M.smegmatis_MC2_155 RIGHGRLFALYVASYCVGRFWVELMRSDTATEFAG--------IRVNTFT TH_1073|M.thermoresistible__bu RLGHGRLFALYVAGYCVGRFWVELLRSDFATHIAG--------IRINSFT Mflv_3597|M.gilvum_PYR-GCK KIGHGRLFALYVAGYCAGRFWIELMRSDTATLLAG--------IRVNTFT Mvan_2819|M.vanbaalenii_PYR-1 KIGHGRLFALYVAGYCVGRFWIELMRSDTATLLAG--------IRVNSFT MUL_3715|M.ulcerans_Agy99 EPPHPGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLPSME * :* * . .:: :: : * : :: Mb1640|M.bovis_AF2122/97 STFVFIG-AVVYIILAPKGREAPGALRGSEYVVDEALEREPAELAAAAVA Rv1614|M.tuberculosis_H37Rv STFVFIG-AVVYIILAPKGREAPGALRGSEYVVDEALEREPAELAAAAVA MLBr_01274|M.leprae_Br4923 STFVFIG-AVVYIILAPKGREEPENLCRAEYVAREIPEPESATERATVAS MMAR_2416|M.marinum_M STFVFIG-AVVYIILAPKGREDPASVRGTAAAAEEVPEPEPAGEVATAAA MAV_3172|M.avium_104 STFVFIG-AVVYLMAAPKGREDPESLRGNQYVEEEPAEPEPATVAATTEA MAB_2642c|M.abscessus_ATCC_199 STLVFVG-AVAYILLAPKGREDPATLGG-TPSSADGGDD----------- MSMEG_3222|M.smegmatis_MC2_155 STFVFIG-AVVYIMLAPKGREEPESLRGKAADETEEGDEESLVDEAGKEL TH_1073|M.thermoresistible__bu ASFVFIG-AVVYIMVAPKGREDPATLGG--PVQTDAGADTG--------- Mflv_3597|M.gilvum_PYR-GCK ATFVFVA-AVVYVIVAPKGREAPESLRGNQDAESDVEDLAKDVALASAVG Mvan_2819|M.vanbaalenii_PYR-1 STFVFIG-AVVYIMAAPKGREDPSSLKGNQDAEARVEDLAKDVAVGSATG MUL_3715|M.ulcerans_Agy99 AAFVDIGRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYIVVQVSKD :::* :. . :: * : . . : Mb1640|M.bovis_AF2122/97 SAASAVG---------------PVGPGEPNQPDDVAEAVKAEVAEVTDEV Rv1614|M.tuberculosis_H37Rv SAASAVG---------------PVGPGEPNQPDDVAEAVKAEVAEVTDEV MLBr_01274|M.leprae_Br4923 -----------------------------------TYATTTAVPVSADEE MMAR_2416|M.marinum_M PAGDTEGD-------------EPTGLAETAKAAEVAEPETVGSAVAGDES MAV_3172|M.avium_104 -----------------------------------ATEGVAAPADGAEAA MAB_2642c|M.abscessus_ATCC_199 ------------------------TAETEATADTEDTEDTED--GVTDAP MSMEG_3222|M.smegmatis_MC2_155 VAAAAGTG-------------VVAAATAAAREDTDDTDGTTDPAAASDEP TH_1073|M.thermoresistible__bu ------------------------AAGADAEVDTEVDTEKEDVAAAVRGV Mflv_3597|M.gilvum_PYR-GCK VVAAATVAGEDEKRDG--GGSPPGGLGSVEGDEALEAAGGASAANESAVE Mvan_2819|M.vanbaalenii_PYR-1 IVAAATVADEDE-------AMEPADDDDAAEVEALVAELEASEP-ETEGL MUL_3715|M.ulcerans_Agy99 PVGHKGARLTTQVSLAGRYLVYVAGASSTGISRKLPDTERQRLKEILREV Mb1640|M.bovis_AF2122/97 AAESVVQV-------ADRDGESTPAVEETSEADIEREQPGD--------- Rv1614|M.tuberculosis_H37Rv AAESVVQV-------ADRDGESTPAVEETSEADIEREQPGD--------- MLBr_01274|M.leprae_Br4923 FAETN--------------------------------------------- MMAR_2416|M.marinum_M TADTEASD-------AVESEVGEAAEAEAPEAEAEEAEVGEV-------- MAV_3172|M.avium_104 GADATAQR-------PEESAEPDVEKPESEETEAEAAEEPE--------- MAB_2642c|M.abscessus_ATCC_199 --EAD--------------ATDKSVDESADNSGIVEK------------- MSMEG_3222|M.smegmatis_MC2_155 GDEAEPETEAATAVLTADGAEAMSVDEQPDDDEAVDEEAGQEAEEPADEL TH_1073|M.thermoresistible__bu AGAGAXX------------XRHIARRRGRRRGERIRRRR----------- Mflv_3597|M.gilvum_PYR-GCK GAADAADLVALLEASEDVEVADGAVEPQEVDAPPVPDEAGGLGAVEGEEA Mvan_2819|M.vanbaalenii_PYR-1 GSVEGDEVAEAVEVAP--EVHEAAVEG-EAEAEELASDVEGAPEPEGVEA MUL_3715|M.ulcerans_Agy99 VPSDAGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKAVEIKQKAAGAA Mb1640|M.bovis_AF2122/97 --------------------------------LAGQAPAAHQVDAEAASA Rv1614|M.tuberculosis_H37Rv --------------------------------LAGQAPAAHQVDAEAASA MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M ----------------EVAEAVEGEVEEAEEAEPGEVEVAEAVEGEVEAA MAV_3172|M.avium_104 ----------------------------------SEETEAAEEPGEPEAE MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 VELADEPEGEPEPAAAEEAEPAETIEPDEDEIFDAELAEALAEAAEDFAV TH_1073|M.thermoresistible__bu ----------------------------RRQLVDRRRVQWLRRG-----I Mflv_3597|M.gilvum_PYR-GCK AEAAAGAGAARASVSDDAEASNDADAETEAAGLGSVDGDEVAAAVEDAPE Mvan_2819|M.vanbaalenii_PYR-1 AEAEAESPVDGAEAESEVVEG-DVESVTESEGLGSVEGDEVAEAVEVAPE MUL_3715|M.ulcerans_Agy99 VALYEEPDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVSK Mb1640|M.bovis_AF2122/97 APEEPAALASEAHDETEP-------------------------------- Rv1614|M.tuberculosis_H37Rv APEEPAALASEAHDETEP-------------------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M AEAEEAEEAEEAEEAEEAEEAEPGEIEVAEAVEGEVEAAAEAEEAEVGEV MAV_3172|M.avium_104 EPEEPEAEEPEEPETEEP-------------------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 VPESAGSDEAEVAAAESAADAEDGPSDAESAEVPAEAAADDAVVSEPAGT TH_1073|M.thermoresistible__bu VHHIARGRAGQHLAAG---------------------------------- Mflv_3597|M.gilvum_PYR-GCK VHEAAVEGEAEAEELAAEAEVEAVAAEVAEVDADALTGADDDVDAETEAA Mvan_2819|M.vanbaalenii_PYR-1 VHEVVVEGEAEAEALAADAEAEAEA----EAEAEDLA-ADVEAESPVDGA MUL_3715|M.ulcerans_Agy99 LSKYEPAVGSEGQVGPDVFAVHRIDEHLAKAMDRKVWLPSGGTLVIDRTE Mb1640|M.bovis_AF2122/97 ----EVPEKAAPIP------------------------------------ Rv1614|M.tuberculosis_H37Rv ----EVPEKAAPIP------------------------------------ MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M EAVDEAAEAEAPEVGEIEAAEAVEGEVEVAAEAEEAEAGEDEPKEAEEV- MAV_3172|M.avium_104 ----EADSDEEPEE------------------------------------ MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 VDETEVAEEAAAEAADLEFESYDAELAEA--------------------- TH_1073|M.thermoresistible__bu ------RPRPLALAGQHPLGDRDLLLLGG--------------------- Mflv_3597|M.gilvum_PYR-GCK VEGEAEAEELAAEADAEAQVAAE-VAEVDADALTGADDDVDAETEAEVEG Mvan_2819|M.vanbaalenii_PYR-1 ED-ESEAESEVVEGDVESVTESEGLGSVEGDEVAEAVEVAPEVHEAAVEG MUL_3715|M.ulcerans_Agy99 AMTVVDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVID Mb1640|M.bovis_AF2122/97 -------------------------------------------------- Rv1614|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M --------------AEAEGSEAEDKTVQAIDGGQTGVDDAGEADAEPDDD MAV_3172|M.avium_104 -------------------------------------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------------------- TH_1073|M.thermoresistible__bu -------------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK EAEAEELAAEAD-AEAQVAAEVAEVDAET-LTGADKDVDAEALT-DADAE Mvan_2819|M.vanbaalenii_PYR-1 EAEAEELASDVEGAPEPEGVEAAEAEAESPVDGAEAEAESEVVEGDVESV MUL_3715|M.ulcerans_Agy99 FIDMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGL Mb1640|M.bovis_AF2122/97 ------------------DPAKPDELAVAG-------------------- Rv1614|M.tuberculosis_H37Rv ------------------DPAKPDELAVAG-------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M STAAEPEVVVEQADIEEIEPQEPEAEAVAAAEATDADEGDGEPAEPASDD MAV_3172|M.avium_104 ------------------ESGEAPEQPVAE-------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 ----------------LAEAAEDMAVVVAPAETAESDEAR---------- TH_1073|M.thermoresistible__bu ----------------QVGVRRELAAAVGPPGAGSELQAP---------- Mflv_3597|M.gilvum_PYR-GCK TEAAGLGSVDGDEVAAAVEDAPEVHEAAVEGESEAEELAAEADAEALAEV Mvan_2819|M.vanbaalenii_PYR-1 TESEGLGSVEGDEVAEAVEVAPEVHEVVVEGEAEAEALAADADADADAEA MUL_3715|M.ulcerans_Agy99 IEAFSTSCPHCSGRGILLHADPVDSAPTTGRKADSGGRRNRRSKKNRAEE Mb1640|M.bovis_AF2122/97 -----------------------------PGDDPAEPDG----------- Rv1614|M.tuberculosis_H37Rv -----------------------------PGDDPAEPDG----------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M LDAVAAEDADVDVDATATEAEESGDESPEPAADSEEPEADESAPEDSAED MAV_3172|M.avium_104 ----------------------------EPEPAPQQPET----------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 ---------------------------EPVETDATESEEPSEPEEPDAPE TH_1073|M.thermoresistible__bu ---------------------------VIAVTGVDGPVSARLATGDLIPF Mflv_3597|M.gilvum_PYR-GCK AEIDAEAVNDADED--------------VDAEAEAEAAGLGSVDGDEVAA Mvan_2819|M.vanbaalenii_PYR-1 EDLAADVEAESPVDGAEDESEAEPEAVEGDVESVTESEGLGSVEGDEAAE MUL_3715|M.ulcerans_Agy99 PSEKEAVAKVPTYAPG--EHPMFKAMAASSSSEAEHGDGEVEESGEELTA Mb1640|M.bovis_AF2122/97 -------------------------------------------------- Rv1614|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M TSSGESDTQSELEQ------------------------------------ MAV_3172|M.avium_104 -------------------------------------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 AVEAPEALDENADE------------------------------------ TH_1073|M.thermoresistible__bu GVGG---------------------------------------------- Mflv_3597|M.gilvum_PYR-GCK AVEDAPEVREAVEG---------VAEVDAEALTDAE-------------- Mvan_2819|M.vanbaalenii_PYR-1 AEELVGEVEADVEAETGEAAADEVAEVDAGAVTDTDDDAEGLGSVEGDEV MUL_3715|M.ulcerans_Agy99 AVDDQTAVQVALDLGETEESEETDGTDETDDFDDDSDDSDDSDEDDDTDE Mb1640|M.bovis_AF2122/97 -------------------------IRRQDDFSS---------------- Rv1614|M.tuberculosis_H37Rv -------------------------IRRQDDFSS---------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- MMAR_2416|M.marinum_M ----------------------SQTIEQGSDQTSAG--------DGEGPP MAV_3172|M.avium_104 -------------------------------------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 ----------------------TRAEPAAPAAVAT--------------- TH_1073|M.thermoresistible__bu -----------------------RTGLTGHRQAAT--------------- Mflv_3597|M.gilvum_PYR-GCK --------------------PEESDAEGEPEGPALP------TSEHSPYT Mvan_2819|M.vanbaalenii_PYR-1 AESAEDASEVHEAAVEREEAAEERAAEAEADDASEPQPEEAADTEPAADG MUL_3715|M.ulcerans_Agy99 TNDTDVDADEDEDTDDDSDEDEDTEDDDELDDDLDDELDDDDSDSDDEDS Mb1640|M.bovis_AF2122/97 ----------RRRRWWRLRRRRQ------------------ Rv1614|M.tuberculosis_H37Rv ----------RRRRWWRLRRRRQ------------------ MLBr_01274|M.leprae_Br4923 ----------------------------------------- MMAR_2416|M.marinum_M PSAAVDGDTGPTRQGWRGRLRNRMRRSGR------------ MAV_3172|M.avium_104 ------------KRRWGARLRDRLSGR-------------- MAB_2642c|M.abscessus_ATCC_199 ----------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 ----------APVEPEKGRLRRWLRRNR------------- TH_1073|M.thermoresistible__bu ----------AEHSPGDSDFRDVYG---------------- Mflv_3597|M.gilvum_PYR-GCK VVT--ESSSEPAQSGPAGLVRQWIRRRRNR----------- Mvan_2819|M.vanbaalenii_PYR-1 AVTRVESRSVATESQSGGLLRRMLRRRRSR----------- MUL_3715|M.ulcerans_Agy99 ESELTEPAAGRPAALEVTTIAERPRRRRAAGRPAGPPIHLG