For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RDVRVGLIALLSVMALGLVSTVVSVAAAAARTSVLIMGGSGDPLTTDQDGLPFIRDYTSKVVGNYVIPSA SRPGSGIPGGPYNAVAVITPAQFNSGEPGDTSLTFDDSVAAGAGKLATCIESGDECDINEDLGSDRPAPG DNLVVFGYSQSAAIATLEKARLAALYPYGEGPDVSFILTANGNRPNGGFLARGPKGVTIPLGTPGGGVTF NGSTPTDTQYSTIDVAIQYDGWADQPINPANLLAVANANAGQRLLHPHYADYSLGSPGIIDQGQYGDTRY LMIPTDTLPLLYELSQTPIVGSFLADVLDAPLRVLVESGYDRTSSPGEPKPWTLVPAKDPLKTAADFLVA IPTGWDNAIEDVNGTRPFGTVRPGPFGVGGPDVDYLDPDEDLTKEASKEASKGTELADDSSVKATLVSRL TDATEAEADAVTAKIGAVTEKTQAKVTTLTKPRPQAADEAGDEADAEPSEPSESSESEPSGSETPETSDT KKPMTVAKDSGSEDKAVTKPADAKPEPKEKSEDTSAGKRGRHSSGLTAKPSDKESAPKHRAPDSDTASAK PSREKNSAPKHAAAAKDDRQTKPRAAHGAAAKDAGARDKQHKQDKQDKQAASAAKK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4734 | - | - | 100% (617) | hypothetical protein MSMEG_4734 |
| M. smegmatis MC2 155 | MSMEG_5455 | - | 3e-50 | 31.51% (568) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_2737 | - | 2e-30 | 25.40% (626) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2640 | PPE42 | 4e-37 | 34.51% (368) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_1918 | - | 2e-64 | 37.21% (473) | hypothetical protein Mflv_1918 |
| M. tuberculosis H37Rv | Rv2608 | PPE42 | 5e-37 | 35.07% (365) | PPE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4141 | - | 6e-22 | 24.84% (483) | PE/PPE family protein |
| M. marinum M | MMAR_3427 | - | 3e-34 | 34.28% (353) | PE family protein |
| M. avium 104 | MAV_4817 | - | 2e-09 | 25.30% (253) | ferredoxin, 4Fe-4S |
| M. thermoresistible (build 8) | TH_4029 | - | 2e-59 | 32.80% (564) | PUTATIVE putative PE-PPE, C-terminal domain protein |
| M. ulcerans Agy99 | MUL_2440 | - | 7e-31 | 34.72% (337) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_4726 | - | 2e-70 | 35.87% (538) | hypothetical protein Mvan_4726 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2640|M.bovis_AF2122/97 --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3427|M.marinum_M --------------------------------------------------
MUL_2440|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4726|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1918|M.gilvum_PYR-GCK --------------------------------------------------
TH_4029|M.thermoresistible__bu --------------------------------------------------
MAB_4141|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4817|M.avium_104 MTTQMLIRLVVGMGMTLIVAALAARRVLWLFKLITSGKPAPGHTDDPGKR
Mb2640|M.bovis_AF2122/97 ---------------MNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGLA
Rv2608|M.tuberculosis_H37Rv ---------------MNFAVLPPEVNSARIFAGAGLGPMLAAASAWDGLA
MMAR_3427|M.marinum_M --------------------------------------------------
MUL_2440|M.ulcerans_Agy99 --------------------------------------MLAAAAAWDGTG
MSMEG_4734|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4726|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1918|M.gilvum_PYR-GCK --------------------------------------------------
TH_4029|M.thermoresistible__bu --------------------------------------------------
MAB_4141|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4817|M.avium_104 VWAEVSEVFGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLFQDNF
Mb2640|M.bovis_AF2122/97 EELHAAAGSFASVTTGLAGDAWHGPASLAMTRAASPYVGWLNTAAGQAAQ
Rv2608|M.tuberculosis_H37Rv EELHAAAGSFASVTTGLAGDAWHGPASLAMTRAASPYVGWLNTAAGQAAQ
MMAR_3427|M.marinum_M -------------------MAFLVAEPQVMATVAG-QVEEIGSAIG----
MUL_2440|M.ulcerans_Agy99 QELAAAASAFSSLTSDLAGAAWQGPSAAAMASVATSYVRWLGSAASGAVQ
MSMEG_4734|M.smegmatis_MC2_155 ------------------------MRDVRVGLIALLSVMALGLVST----
Mvan_4726|M.vanbaalenii_PYR-1 --------------------MRRRLRSAAWGLLSLVIAVLFAWGSV----
Mflv_1918|M.gilvum_PYR-GCK -----------------MGKGDFGLKASEFTGRSSTRFADSVRRRP----
TH_4029|M.thermoresistible__bu ------------------------VRSAVLVGCVLTTVLALAWVSP----
MAB_4141|M.abscessus_ATCC_1997 -------------------MAGQYSVPGKRHSLRRYVATITAVAAT----
MAV_4817|M.avium_104 HIPIIGRWDALGFLQDFFATAVFLGIATFAVIRSMRSPREIGRSSRFYGS
Mb2640|M.bovis_AF2122/97 AAGQARLAASAFEATLAATVSPAMVAANRTRLASLVAANLLGQNAPAIAA
Rv2608|M.tuberculosis_H37Rv AAGQARLAASAFEATLAATVSPAMVAANRTRLASLVAANLLGQNAPAIAA
MMAR_3427|M.marinum_M -------------------VANEFAAGS----ISGVAAAAGDEVSAAIAS
MUL_2440|M.ulcerans_Agy99 TARQVATSAAVFEAARTATVPLELVAANRSALMSMVAANVFGLNAPAIAA
MSMEG_4734|M.smegmatis_MC2_155 ------------------VVSVAAAAARTSVLIMGGSGDPLTTDQ-----
Mvan_4726|M.vanbaalenii_PYR-1 ------------------VTSTSAGAG--TALVMGGNGHPLSVPQ-----
Mflv_1918|M.gilvum_PYR-GCK ------------------GGATYGLYR-HDGLGVGTWAWVFARSSRSFPR
TH_4029|M.thermoresistible__bu ------------------MPAMVQVLA-KTMLVIGGTGHPLVDPS-GPGR
MAB_4141|M.abscessus_ATCC_1997 ------------------CTVLAPLAMESRTIASTLASYVIGIGG-----
MAV_4817|M.avium_104 HTGGAWLVLFMIFNVIWTYVLVRGSAVNNGTLPYGKGAFLSQLFGAILRP
.
Mb2640|M.bovis_AF2122/97 AEAEYEQIWAQDVAAMFGYHSAASAVATQLAPIQEGLQQQLQNVLAQLAS
Rv2608|M.tuberculosis_H37Rv AEAEYEQIWAQDVAAMFGYHSAASAVATQLAPIQEGLQQQLQNVLAQLAS
MMAR_3427|M.marinum_M FFAAHGQAYQAVAGQVEAFHTEFQQALA-QAGNAYVQAEAAG--AAALAG
MUL_2440|M.ulcerans_Agy99 IEAQYEQMWAQNVGAMFGYHVGVSEALSGLAPWQEVLSGVSGRVASALEG
MSMEG_4734|M.smegmatis_MC2_155 ----------------------------------DGLPFIRDYTSKVVGN
Mvan_4726|M.vanbaalenii_PYR-1 ----------------------------------DTPDYINKYVTAADDA
Mflv_1918|M.gilvum_PYR-GCK SRRCWRYPRGVPTPVAVLVANTTALVMGGTFHPLTGPRDSPEFVTAYLDN
TH_4029|M.thermoresistible__bu PVDGWPYP---------------SRPLGEPGMATEGDGAPAGYVLLVHDN
MAB_4141|M.abscessus_ATCC_1997 -----------------------------------NNDGASANIPRKLGG
MAV_4817|M.avium_104 LGQPANEYIETAALLAHIAVMLAFLIIVLHSKHMHIFTAPINVIFKRLPN
Mb2640|M.bovis_AF2122/97 GN------------------LGSGNVGVGNIGNDNIGNANIGFGNRGDAN
Rv2608|M.tuberculosis_H37Rv GN------------------LGSGNVGVGNIGNDNIGNANIGFGNRGDAN
MMAR_3427|M.marinum_M --------------------------------------------------
MUL_2440|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4726|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1918|M.gilvum_PYR-GCK --------------------------------------------------
TH_4029|M.thermoresistible__bu --------------------------------------------------
MAB_4141|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4817|M.avium_104 GLGPLLPIEYDGKPIDFENPPDDAVFGRGKVEDFSWKAMLDFATCTECGR
Mb2640|M.bovis_AF2122/97 IGIGNIGDRNLGIGNTGNWNIGIGITGNGQIGFGKPANPDVLVVGNGGPG
Rv2608|M.tuberculosis_H37Rv IGIGNIGDRNLGIGNTGNWNIGIGITGNGQIGFGKPANPDVLVVGNGGPG
MMAR_3427|M.marinum_M ------------------------ALGVPATSAAAPAATIP----PFPAN
MUL_2440|M.ulcerans_Agy99 ------------------------TSAAAAAALGPTALTAAGSALPAAAT
MSMEG_4734|M.smegmatis_MC2_155 --------------------------------YVIPSASRPGSGIPGGPY
Mvan_4726|M.vanbaalenii_PYR-1 --------------------------------FIAP------SGLCGPQC
Mflv_1918|M.gilvum_PYR-GCK --------------------------------AVDN---QISAAYGYAVT
TH_4029|M.thermoresistible__bu --------------------------------FVVP---GGTDGHRYR--
MAB_4141|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4817|M.avium_104 CQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGDKQSPLESTPEGGV
Mb2640|M.bovis_AF2122/97 VTALVMGGTDSLLSLPNIPLLEYAARFITP----VHPGYTATFLETPSQF
Rv2608|M.tuberculosis_H37Rv VTALVMGGTDSLLPLPNIPLLEYAARFITP----VHPGYTATFLETPSQF
MMAR_3427|M.marinum_M LTTLVMGGTG--IPIPGPGFINLANELYVR------SANALLGLNTPEEL
MUL_2440|M.ulcerans_Agy99 DVTLVIGGSG--FPIPSQSYVDNVVNNFVTPNFPSFTVSNAISLFTPAES
MSMEG_4734|M.smegmatis_MC2_155 NAVAVITPAQFNSGEPGDTSLTFDDSVAAG-------------------A
Mvan_4726|M.vanbaalenii_PYR-1 SLVATYTPAQIRFVN-GIFDMTYDESVAVG-------------------Q
Mflv_1918|M.gilvum_PYR-GCK NAVAVYTPEEF---FPLGG-LTFDDSVAEG-------------------L
TH_4029|M.thermoresistible__bu -AVAVYTPQEF---FPVAGSRTFNDSVTDG-------------------F
MAB_4141|M.abscessus_ATCC_1997 -----------------AYSVDYHPVSYPG------------------AI
MAV_4817|M.avium_104 GEELSGEKHAEAHHVPESGFGRVMGSGPEQATRPLVGTEEQGGVIDPDVL
Mb2640|M.bovis_AF2122/97 FPFTGLNSLTYDVSVAQG-----VTNLHTAIMAQLAA-GNEVVVFG----
Rv2608|M.tuberculosis_H37Rv FPFTGLNSLTYDVSVAQG-----VTNLHTAIMAQLAA-GNEVVVFG----
MMAR_3427|M.marinum_M YPLTGTKSLTLDASVSEG-----LTILDNAIMEQLAIPGNTVTVFG----
MUL_2440|M.ulcerans_Agy99 YWITGIKTMTEDASWAEG-----LTILDTAIKAQLAA-GNNVVVQG----
MSMEG_4734|M.smegmatis_MC2_155 GKLATCIESGDECDINED-----LGSD--RPAPGDN-----LVVFG----
Mvan_4726|M.vanbaalenii_PYR-1 ANLNDCIQGSDCTATLAP-----YSETGPHTVADST-----YVIYA----
Mflv_1918|M.gilvum_PYR-GCK ANLGRCLRAEPGCVFNAD-----PAVAARVG-TVAPRHDDTFVVFG----
TH_4029|M.thermoresistible__bu ANTVNCAHSSAGCIAHIY-----PDTDVGLTDPVADDDGSGVVVVG----
MAB_4141|M.abscessus_ATCC_1997 WPVSGLTAPTFKTSVAQG-----RTNLNDEIVTAGNQ---PITIVG----
MAV_4817|M.avium_104 WSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEFPSELSVLFKNLET
.:
Mb2640|M.bovis_AF2122/97 ---------------------------------------TSQSATIATFE
Rv2608|M.tuberculosis_H37Rv ---------------------------------------TSQSATIATFE
MMAR_3427|M.marinum_M ---------------------------------------VSQSAVIASLE
MUL_2440|M.ulcerans_Agy99 ---------------------------------------YSQGAGIASLE
MSMEG_4734|M.smegmatis_MC2_155 ---------------------------------------YSQSAAIATLE
Mvan_4726|M.vanbaalenii_PYR-1 ---------------------------------------YSQSATVAANQ
Mflv_1918|M.gilvum_PYR-GCK ---------------------------------------YSQSAAVASLL
TH_4029|M.thermoresistible__bu ---------------------------------------YSQSAVIASLV
MAB_4141|M.abscessus_ATCC_1997 ---------------------------------------YSLGAVVVSKS
MAV_4817|M.avium_104 KANPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYEYLFWVGCAGAYDD
.. .
Mb2640|M.bovis_AF2122/97 MRYLQSLPAHLRPGLDELSFTLTGNPNRPDGGILTRFG------FSIPQL
Rv2608|M.tuberculosis_H37Rv MRYLQSLPAHLRPGLDELSFTLTGNPNRPDGGILTRFG------FSIPQL
MMAR_3427|M.marinum_M MQKLAALGP-AAPTASQLNFVLLGNEMNPNGGLLARFPD-----LSIPSL
MUL_2440|M.ulcerans_Agy99 MSNLKAAG---VPTGS-VSFSLIGNAMNPNGGLYERFAG-----LVSPSL
MSMEG_4734|M.smegmatis_MC2_155 KARLAALYPY--GEGPDVSFILTANGNRPNGGFLARGPKGVTIPLGTPGG
Mvan_4726|M.vanbaalenii_PYR-1 KLQLIAHP-----VASTVSFLLVANPNRPDGGILER-----FVGAYIPLL
Mflv_1918|M.gilvum_PYR-GCK KRQLIDAPG---PEPAATTFMLAANPMRPNGGVLGRFP-----ALTIPIL
TH_4029|M.thermoresistible__bu KQHLLDNPD---RAPG-TSFVLLGNPMRPNGGLLQRLPR----GMTIPIL
MAB_4141|M.abscessus_ATCC_1997 HSDLLQRYP---GGNPNIQFVLMGSANTPNGGIFARFP-----WLKIPLA
MAV_4817|M.avium_104 KAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSARRSGNEFLFQQLAAQA
: : . :*. * .
Mb2640|M.bovis_AF2122/97 GFTLSGATP-ADAYP--------TVDYAFQYDGVN-DFPKYPLNVFATAN
Rv2608|M.tuberculosis_H37Rv GFTLSGATP-ADAYP--------TVDYAFQYDGVN-DFPKYPLNVFATAN
MMAR_3427|M.marinum_M GLTFYGGTPSDTIYP--------TANYTLEYDGFA-DFPRYPLNFISDLN
MUL_2440|M.ulcerans_Agy99 GKTFWGATP-DNYYT--------TDVYTLEYDGFA-DFPRYPPNFVSDLN
MSMEG_4734|M.smegmatis_MC2_155 GVTFNGSTPTDT--------QYSTIDVAIQYDGWA-DQPINPANLLAVAN
Mvan_4726|M.vanbaalenii_PYR-1 GITFNGSTPTFSPQPR----PLTTVDVARQYDGWA-DFPTNPLNLLADLN
Mflv_1918|M.gilvum_PYR-GCK GITFHGATPTAGVDG-----AYRTVDVVRQYDGLGGDFPVRPLNLLATVN
TH_4029|M.thermoresistible__bu DVTAFGPTPTNSCDEQGENCAHPTLDVAVQHDALGGDFPIYPLHLPAVAN
MAB_4141|M.abscessus_ATCC_1997 DIESNGAWEPDQFKT---------KVINTEYDTYG-DFPAY-FNPLALAN
MAV_4817|M.avium_104 VETLDGVFEGVETVDR-----KIVVTCPHCFNTLGREYRQLGANYTVLHH
* .: : : :
Mb2640|M.bovis_AF2122/97 AIAGILFLHS-------GLIALPPDLASGVVQPVSSP--DVLTTYILLPS
Rv2608|M.tuberculosis_H37Rv AIAGILFLHS-------GLIALPPDLASGVVQPVSSP--DVLTTYILLPS
MMAR_3427|M.marinum_M AVMGIVYVHP-------TYLDLTQAQVDNAIPLATSPGYSGVTSYYILPT
MUL_2440|M.ulcerans_Agy99 AIMGIYYVHT-------QYPTLTAAQVATAFTLPTEG--ATMTTYHMIPT
MSMEG_4734|M.smegmatis_MC2_155 ANAGQRLLHP-------HYADYSLGSPGIIDQGQYGD-----TRYLMIPT
Mvan_4726|M.vanbaalenii_PYR-1 AIMGTILLHP-------NYSDAGTP----QLQGQYQD-----STYYLIPA
Mflv_1918|M.gilvum_PYR-GCK ALLGYGIMHG-------ETVDVPFAQ--ARFQGREGD-----TDYYLIGT
TH_4029|M.thermoresistible__bu SLLSYALLHG-------TMPEQHLDD--AVPQGVHGD-----TTYYLLPT
MAB_4141|M.abscessus_ATCC_1997 SIAAIQYAHPDAYYDRIDPAALDDPDNPNVVKTVQGN-----TTYYLVRA
MAV_4817|M.avium_104 TQLLNRLIRDNK-LVPVTPVSQDITYHDPCYLGRHNKVYEAPRELIGAAG
: :
Mb2640|M.bovis_AF2122/97 QDLPLLVPLRAI--PLLGNPLADLIQPDLRVLVELGYDR------TAHQD
Rv2608|M.tuberculosis_H37Rv QDLPLLVPLRAI--PLLGNPLADLIQPDLRVLVELGYDR------TAHQD
MMAR_3427|M.marinum_M ENLPLLEPLRAI--PVIGNPLANLIQPDLKVLVNLGYGDPAYGYSTSPAD
MUL_2440|M.ulcerans_Agy99 ENLPLLEPLRGV--PFIGNTLADLVQPDLKVLVNLGYGDPNYGYSTGPAN
MSMEG_4734|M.smegmatis_MC2_155 DTLPLLYELSQT--PIVGSFLADVLDAPLRVLVESGYDR------TSSPG
Mvan_4726|M.vanbaalenii_PYR-1 PITPVLVPLTWV--PIVGKPLAIALDPAVRVLVEMGYDR------TVNPG
Mflv_1918|M.gilvum_PYR-GCK DLLPLLQPLLL----FVPRPILSALDAPLRVLVEDAYDR------DAGPG
TH_4029|M.thermoresistible__bu DLVPLLMPFEG----VVPRPILVALDEPLRVLIEGGYRR------DISPG
MAB_4141|M.abscessus_ATCC_1997 EHLPLLQPLRDLTNPIGASFVLDAIEPTLRVFIDMAYDR------DTGPG
MAV_4817|M.avium_104 ANLTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEALATGAATVA
. : :: : ::
Mb2640|M.bovis_AF2122/97 VPSPFGLFP---------------DVDWAEVAADLQQGAVQGVNDALSGL
Rv2608|M.tuberculosis_H37Rv VPSPFGLFP---------------DVDWAEVAADLQQGAVQGVNDALSGL
MMAR_3427|M.marinum_M ITTPFGLFP---------------DVPPHVIADALVAGTKQGISDFSADI
MUL_2440|M.ulcerans_Agy99 VPTPFGLFP---------------DVAPATVFDALVAGTQQGISDAAADI
MSMEG_4734|M.smegmatis_MC2_155 EPKPWTLVP---------------AKDPLKTAADFLVAIPTGWDNAIEDV
Mvan_4726|M.vanbaalenii_PYR-1 QPTPARYLY---------------VPNLIKAALNFAMAIPTGWDDAISYL
Mflv_1918|M.gilvum_PYR-GCK DPTTARWWP---------------VKDFAGTAAKLIASVPVAVDNLTEGF
TH_4029|M.thermoresistible__bu EPTPAYLIP---------------VINPVSLTVNLIRSVPVGLDNGIEEL
MAB_4141|M.abscessus_ATCC_1997 TTTQFSFFTP--------------SKNIVDAFNKLPTAIAEGAHNVENGL
MAV_4817|M.avium_104 TACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQILLGSLEYDKATLPEKG
. : .
Mb2640|M.bovis_AF2122/97 G-------------------------------------------------
Rv2608|M.tuberculosis_H37Rv G-------------------------------------------------
MMAR_3427|M.marinum_M --QQMFSQPATLPS------------------------------------
MUL_2440|M.ulcerans_Agy99 GAWQLPSLPDISLSGISNALGSDP--------------------------
MSMEG_4734|M.smegmatis_MC2_155 NG---TRPFGTVRPG-PFGVGGPDVDYLDPDEDLTKEASKEASKGTELAD
Mvan_4726|M.vanbaalenii_PYR-1 TGDPDCRPFHTTVPASPFGVGGP---------------------------
Mflv_1918|M.gilvum_PYR-GCK GL---GRVLGTPVPG-VFGVGG----------------------------
TH_4029|M.thermoresistible__bu TG---ERPLGTTDPG-PYGVGGDD--------------------------
MAB_4141|M.abscessus_ATCC_1997 AGATPKQSASPEKPASPPVPQPGPTN------------------------
MAV_4817|M.avium_104 TAAKEAEKRAAQAPKATATVEAPAKETTKEP-------------------
Mb2640|M.bovis_AF2122/97 -----------------LPPPWQPALPRLF--------------------
Rv2608|M.tuberculosis_H37Rv -----------------LPPPWQPALPRLF--------------------
MMAR_3427|M.marinum_M -----------------PPMLQAPDLMAALAAAPTP-VEVVNTLTKIVSD
MUL_2440|M.ulcerans_Agy99 ---------WSALSNATLPTLSVSTIENAIKGVQTATTDIANTISFDATT
MSMEG_4734|M.smegmatis_MC2_155 DSSVKATLVSRLTDATEAEADAVTAKIGAVTEKTQAKVTTLTKPRPQAAD
Mvan_4726|M.vanbaalenii_PYR-1 ---------PVYTGAIDPYGEPTPYLAPPVETHGEAAPGSGSPAAHPAGT
Mflv_1918|M.gilvum_PYR-GCK ---------PDLPDVDEGGAVTSDIDEDAVAQRDSASSTERSAPAEESRS
TH_4029|M.thermoresistible__bu ---------ADLRGLPAGLVPLGSTSPTPILPETAAPAAEKPAMRVDSGT
MAB_4141|M.abscessus_ATCC_1997 --------PGSATTQIPAPEAPTPSVVSLSTAEPPAPPASAKAADPTAIS
MAV_4817|M.avium_104 -------AEAAPKAEAAPAAPAAPVKGLGIAGGAKRPGAKKSAPAAEAKT
Mb2640|M.bovis_AF2122/97 --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3427|M.marinum_M DYATLLPLADIGTAFVITMPT------YDATLFVD---QLLQGN---LIN
MUL_2440|M.ulcerans_Agy99 AYATLLPTADVVNAMVTTLPA------YNLKLFLDGILQVLDGDPAGLIY
MSMEG_4734|M.smegmatis_MC2_155 EAGDEADAEPSEPSESSESEPSGSETPETSDTKKPMTVAKDSGSEDKAVT
Mvan_4726|M.vanbaalenii_PYR-1 EPPETVTFSPTTESTPSTLLP---ETPAESEDMPPDFVENDTPDSDEVSP
Mflv_1918|M.gilvum_PYR-GCK AVGGADSDGRDDVVDPEPAAP-------EAETS-----------EAETVT
TH_4029|M.thermoresistible__bu PKPIIRTAAPSAPLLRTPRPP-------AGERLGERLGERLNQRRGPILD
MAB_4141|M.abscessus_ATCC_1997 VSTAGASTARDQDFQPDTKPDPKSTPPPTKDSVGEADKSKNTLKPTLRLP
MAV_4817|M.avium_104 EAPAEAKTEAPAAPAKGLGIAAGAKRPGAKKSAPAAQAPKTEAPKTEAPK
Mb2640|M.bovis_AF2122/97 --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3427|M.marinum_M AFGYPIAADVGLTAISGG-------------VVALVAIGTLQSNIKDLQS
MUL_2440|M.ulcerans_Agy99 ALGAPIAADTALVTLLAG-------------FNLYAYLYAFN---KILPG
MSMEG_4734|M.smegmatis_MC2_155 KPADAKPEPKEKSEDTSAGKRGRHSSGLTAKPSDKESAPKHRAPDSDTAS
Mvan_4726|M.vanbaalenii_PYR-1 TEDDALKDTETINESQDG-----PTESASGVSGEDAADADSRSADADSLS
Mflv_1918|M.gilvum_PYR-GCK ETEADDADDADDGADADD-------------EDIDADGADADGEDTAGNT
TH_4029|M.thermoresistible__bu ASRLLRPGRAAAGRGVTD-------------TGRPGPVDAAPNPESDTKS
MAB_4141|M.abscessus_ATCC_1997 KLPVAQPGTAPKSPKFPSLKNHLKSVPGLSEKKNPAADASSKHSQPANAP
MAV_4817|M.avium_104 TEAKTEAAGEAKTEAPAAPAAPVKGLGIAAGAKRPGAKKAAPKAEAPKAE
Mb2640|M.bovis_AF2122/97 --------------------------------------------------
Rv2608|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3427|M.marinum_M LFP-----------------------------------------------
MUL_2440|M.ulcerans_Agy99 VL------------------------------------------------
MSMEG_4734|M.smegmatis_MC2_155 AKPSREKNSAPKHAAAAKDDRQTKPRAAHGAAAKDAGARDKQHKQDKQDK
Mvan_4726|M.vanbaalenii_PYR-1 ADAG---DSAPADAAAADTAA-----------------------------
Mflv_1918|M.gilvum_PYR-GCK AEAA----------------------------------------------
TH_4029|M.thermoresistible__bu QEQP----------------------------------------------
MAB_4141|M.abscessus_ATCC_1997 AHTSDKTSDHASETGRGAA-------------------------------
MAV_4817|M.avium_104 AEAAKAEAPKPEAPKAEAESKPEPAKPSNGEGGSSKPSQPPVKGLGIARG
Mb2640|M.bovis_AF2122/97 --------
Rv2608|M.tuberculosis_H37Rv --------
MMAR_3427|M.marinum_M --------
MUL_2440|M.ulcerans_Agy99 --------
MSMEG_4734|M.smegmatis_MC2_155 QAASAAKK
Mvan_4726|M.vanbaalenii_PYR-1 --------
Mflv_1918|M.gilvum_PYR-GCK --------
TH_4029|M.thermoresistible__bu --------
MAB_4141|M.abscessus_ATCC_1997 --------
MAV_4817|M.avium_104 ARPPGKR-