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MTATVLAYFPSPPRGVWHLGPLPIRAYAFFIIIGIVMGLMIGDRRFAARGGERGVIYDIALWMVPFGLIG GRLYHLSTDWQTYFGEGGAGLGAALRIWDGGLGIWGAVTLGTVGAWIGCRRRGIPLPAFLDAVAPGVVMG QAIGRLGNYFNQELYGRETTVPWGLEIFYRRDPSGFVDVHSLDGVSTGQVAVVVQPTFLYELIWNLLVFA ALIYLDRRFTIGHGRLFASYVALYCVGRFCVELLRDDTATHIAGIRINSFTSTFVFIGAVVYIILAPKGR EDPASVRGTAAAAEEVPEPEPAGEVATAAAPAGDTEGDEPTGLAETAKAAEVAEPETVGSAVAGDESTAD TEASDAVESEVGEAAEAEAPEAEAEEAEVGEVEVAEAVEGEVEEAEEAEPGEVEVAEAVEGEVEAAAEAE EAEEAEEAEEAEEAEEAEPGEIEVAEAVEGEVEAAAEAEEAEVGEVEAVDEAAEAEAPEVGEIEAAEAVE GEVEVAAEAEEAEAGEDEPKEAEEVAEAEGSEAEDKTVQAIDGGQTGVDDAGEADAEPDDDSTAAEPEVV VEQADIEEIEPQEPEAEAVAAAEATDADEGDGEPAEPASDDLDAVAAEDADVDVDATATEAEESGDESPE PAADSEEPEADESAPEDSAEDTSSGESDTQSELEQSQTIEQGSDQTSAGDGEGPPPSAAVDGDTGPTRQG WRGRLRNRMRRSGR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2416 | lgt | - | 100% (714) | prolipoprotein diacylglyceryl transferases Lgt |
M. marinum M | MMAR_5242 | - | 8e-10 | 50.00% (88) | hypothetical protein MMAR_5242 |
M. marinum M | MMAR_3768 | rne | 8e-10 | 23.27% (275) | ribonuclease E Rne |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1640 | lgt | 1e-153 | 62.44% (450) | prolipoprotein diacylglyceryl transferase |
M. gilvum PYR-GCK | Mflv_3597 | - | 1e-165 | 47.17% (778) | prolipoprotein diacylglyceryl transferase |
M. tuberculosis H37Rv | Rv1614 | lgt | 1e-153 | 62.44% (450) | prolipoprotein diacylglyceryl transferase |
M. leprae Br4923 | MLBr_01274 | - | 1e-146 | 76.51% (315) | putative prolipoprotein diacylglyceryl transferase |
M. abscessus ATCC 19977 | MAB_2642c | - | 1e-132 | 61.01% (377) | prolipoprotein diacylglyceryl transferase |
M. avium 104 | MAV_3172 | - | 1e-165 | 67.20% (439) | prolipoprotein diacylglyceryl transferase |
M. smegmatis MC2 155 | MSMEG_3222 | - | 1e-154 | 51.70% (617) | prolipoprotein diacylglyceryl transferase |
M. thermoresistible (build 8) | TH_1073 | lgt | 1e-127 | 68.10% (326) | Possible prolipoprotein diacylglyceryl transferases Lgt |
M. ulcerans Agy99 | MUL_3715 | rne | 4e-10 | 26.98% (189) | ribonuclease E Rne |
M. vanbaalenii PYR-1 | Mvan_2819 | - | 1e-169 | 50.69% (726) | prolipoprotein diacylglyceryl transferase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2416|M.marinum_M MTATVLAYFPSPPRGVWHLGPLPIRAYAFFIIIG---------------- MLBr_01274|M.leprae_Br4923 MTRMLPGYFPSPPRGVWHLGPLPIRAYALLIILG---------------- Mb1640|M.bovis_AF2122/97 -MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITG---------------- Rv1614|M.tuberculosis_H37Rv -MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITG---------------- MAV_3172|M.avium_104 -MTKLLAYFPSPPQGVWHLGPVPIRAYALFIIAG---------------- MAB_2642c|M.abscessus_ATCC_199 MTVVNLAYIPSPPQGVWHLGPIPIRAYALCIIAG---------------- MSMEG_3222|M.smegmatis_MC2_155 MTTTVLAYLPSPSQGVWHLGPVPIRAYALCIIVG---------------- TH_1073|M.thermoresistible__bu -VTTTLAYIPSPAQGVWQLGPIPIRAYALCIIAG---------------- Mflv_3597|M.gilvum_PYR-GCK MTTTVLAYIPSPPQGVWYLGPFPLRAYALCIIVG---------------- Mvan_2819|M.vanbaalenii_PYR-1 MTTTVLAYIPSPSQGVWHLGPFPVRAYALFIIVG---------------- MUL_3715|M.ulcerans_Agy99 MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR . *. * :*.::. * MMAR_2416|M.marinum_M --------------IVMGLMIGDRRFAARGGERGVIYDIALWMVPFG--- MLBr_01274|M.leprae_Br4923 --------------IVAALVVGGRCWEARGGERDVTYDIALWAVPFG--- Mb1640|M.bovis_AF2122/97 --------------IIVALLIGDRRLTARGGERGMTYDIALWAVPFG--- Rv1614|M.tuberculosis_H37Rv --------------IIVALLIGDRRLTARGGERGMTYDIALWAVPFG--- MAV_3172|M.avium_104 --------------IVAALLIGDRRWEARGGERGVIYDIALWTVPFG--- MAB_2642c|M.abscessus_ATCC_199 --------------IVAALIIGDRRWEQRGGERGVIYDIALWAVPFG--- MSMEG_3222|M.smegmatis_MC2_155 --------------IVAALVIGDRRWQARGGEPGVIYDIALWAVPFG--- TH_1073|M.thermoresistible__bu --------------IVVALVLGDRRWAARGGERGVIYDIALWAVPFG--- Mflv_3597|M.gilvum_PYR-GCK --------------IVAALVIGDRRWVARGGEPGVIYDIALWAVPFG--- Mvan_2819|M.vanbaalenii_PYR-1 --------------IIAALVIGDRRWVARGGESGVIYDIALWAVPFG--- MUL_3715|M.ulcerans_Agy99 IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEDQQAPDAVAAEVPDAPGE : *: :. * * . ** . MMAR_2416|M.marinum_M ---------LIGGRLYHLSTDWQT-------------------------- MLBr_01274|M.leprae_Br4923 ---------LVGGRLYHLATDWRT-------------------------- Mb1640|M.bovis_AF2122/97 ---------LIGGRLYHLATDWRT-------------------------- Rv1614|M.tuberculosis_H37Rv ---------LIGGRLYHLATDWRT-------------------------- MAV_3172|M.avium_104 ---------LVGGRLYHLATDWRT-------------------------- MAB_2642c|M.abscessus_ATCC_199 ---------LVGGRLYHVMTDWQT-------------------------- MSMEG_3222|M.smegmatis_MC2_155 ---------LAGGRIYHVITDWKT-------------------------- TH_1073|M.thermoresistible__bu ---------LIGGRVYHVLTDWRT-------------------------- Mflv_3597|M.gilvum_PYR-GCK ---------LIGGRLYHVITDWPT-------------------------- Mvan_2819|M.vanbaalenii_PYR-1 ---------LIGGRLYHVITDWPT-------------------------- MUL_3715|M.ulcerans_Agy99 PAEPESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDADDE * . :: * MMAR_2416|M.marinum_M --------------------YFGEGGAGLGAALRIWDGGLGIWG------ MLBr_01274|M.leprae_Br4923 --------------------YFGQNGAGLGAALRIWDGGLGIWG------ Mb1640|M.bovis_AF2122/97 --------------------YFGDGGAGLAAALRIWDGGLGIWG------ Rv1614|M.tuberculosis_H37Rv --------------------YFGDGGAGLAAALRIWDGGLGIWG------ MAV_3172|M.avium_104 --------------------YWGPGGAGFGAAVRIWDGGLGIWG------ MAB_2642c|M.abscessus_ATCC_199 --------------------YFGAHGKGIGKAIAVWEGGLGIWG------ MSMEG_3222|M.smegmatis_MC2_155 --------------------YFGPTGKGFGAALQIWEGGLGIWG------ TH_1073|M.thermoresistible__bu --------------------YFGPDGAGFVAALRIWDGGLGIWG------ Mflv_3597|M.gilvum_PYR-GCK --------------------YFGDGGAGPAAALRIWDGGLGIWG------ Mvan_2819|M.vanbaalenii_PYR-1 --------------------YFGEGGAGPAAALRIWDGGLGIWG------ MUL_3715|M.ulcerans_Agy99 SGDEGDDDEEQADRPGNRRRRRGRRGRGRGRGEQGANDGQDQPGDDGDEA * * * . :.* . * MMAR_2416|M.marinum_M -----------------------------AVTLGTVGAWIGCRRRGIPLP MLBr_01274|M.leprae_Br4923 -----------------------------AVALGCVGAWLGCRRHRIPLP Mb1640|M.bovis_AF2122/97 -----------------------------AVTLGVMGAWIGCRRCGIPLP Rv1614|M.tuberculosis_H37Rv -----------------------------AVTLGVMGAWIGCRRCGIPLP MAV_3172|M.avium_104 -----------------------------AVALGAVGAWIGCRRHGIPLP MAB_2642c|M.abscessus_ATCC_199 -----------------------------AVALGGVGAWIACRRRGIPLP MSMEG_3222|M.smegmatis_MC2_155 -----------------------------AVAFGAVGAWIACRLRGIPLP TH_1073|M.thermoresistible__bu -----------------------------AVALGGVGAWIACRRHGIPLP Mflv_3597|M.gilvum_PYR-GCK -----------------------------AVALGAVGAWIACRRRGIPLP Mvan_2819|M.vanbaalenii_PYR-1 -----------------------------AVALGGIGAWIACRRRGIPLP MUL_3715|M.ulcerans_Agy99 PQKAGGNSTSSDDSEAQDGADSEESDNGDDDNGSADGASRRRRRRRRRKS . ** * . MMAR_2416|M.marinum_M AFLDAVAPG--------VVMGQAIGRLGNYFN----------QELYGRET MLBr_01274|M.leprae_Br4923 AFGDALAPG--------IILAQAIGRLGNYFN----------QELYGRET Mb1640|M.bovis_AF2122/97 VLLDAVAPG--------VVLAQAIGRLGNYFN----------QELYGRET Rv1614|M.tuberculosis_H37Rv VLLDAVAPG--------VVLAQAIGRLGNYFN----------QELYGRET MAV_3172|M.avium_104 AFADALAPG--------IILAQAIGRLGNYFN----------QELYGRET MAB_2642c|M.abscessus_ATCC_199 AFADAIAPG--------IVLAQAIGRLGNYFN----------QELTGGPT MSMEG_3222|M.smegmatis_MC2_155 AFGDAIAPG--------IILAQGIGRLGNYFN----------QELYGRPT TH_1073|M.thermoresistible__bu AFGDAIAPG--------IVLAQAIGRLGNYFN----------QELYGRPT Mflv_3597|M.gilvum_PYR-GCK AFGDAIAPG--------IVLAQAIGRLGNYFN----------QELYGRET Mvan_2819|M.vanbaalenii_PYR-1 AFGDAIAPG--------IVLAQAIGRLGNYFN----------QELFGRET MUL_3715|M.ulcerans_Agy99 GAGDDGDEGPAPDDPPNTVVHERAPRSGDKSGNSDSGDDSGGNEIKGIDG * * :: : * *: . :*: * MMAR_2416|M.marinum_M TVPWGLEIFYRRD--------PSGFVDVHSLDGVSTGQVAVVVQPTFLYE MLBr_01274|M.leprae_Br4923 TMPWGLEVFYRRD--------PAGYMDPHSLDGVSTGQLAFVVQPTFLYE Mb1640|M.bovis_AF2122/97 TMPWGLEIFYRRD--------PSGFDVPNSLDGVSTGQVAFVVQPTFLYE Rv1614|M.tuberculosis_H37Rv TMPWGLEIFYRRD--------PSGFDVPNSLDGVSTGQVAFVVQPTFLYE MAV_3172|M.avium_104 TLPWGLEIFYRRD--------PSGYIDPHSLDGVSTGQVALVVQPTFLYE MAB_2642c|M.abscessus_ATCC_199 TLPWGLELFYRRS--------ADGTVDVLNLNGVSTGEVAQVVHPTFLYE MSMEG_3222|M.smegmatis_MC2_155 DVPWGLEIYERLN--------KFGQSD--QLNGVSTGQVTAVVHPTFLYE TH_1073|M.thermoresistible__bu TLPWGLEIYERRN--------ASGALD--PLNGTSTGELLAVVHPTFLYE Mflv_3597|M.gilvum_PYR-GCK TVPWGLEIYERRN--------SAGVLD--SLNGISTGELIGVVHPTFLYE Mvan_2819|M.vanbaalenii_PYR-1 TVPWGLEIYERVN--------AAGVPD--SLNGVSTGELIQVVHPTFLYE MUL_3715|M.ulcerans_Agy99 STRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTE : * . * .: : **: . * MMAR_2416|M.marinum_M LIWNLLVFAALIYLDRRFTIGHGRLFASYVALYCVGRFCVELLR-DDTAT MLBr_01274|M.leprae_Br4923 LIWNVLVFFALIYVDRWFTLGHGRLFATYVAAYCIGRFCVELLR-DDAAT Mb1640|M.bovis_AF2122/97 LIWNVLVFVALIYIDRRFIIGHGRLFGFYVAFYCAGRFCVELLR-DDPAT Rv1614|M.tuberculosis_H37Rv LIWNVLVFVALIYIDRRFIIGHGRLFGFYVAFYCAGRFCVELLR-DDPAT MAV_3172|M.avium_104 LLWNLLIFVALLYADRRLTLGHGRLFALYVAGYCVGRFCVELLR-DDTAT MAB_2642c|M.abscessus_ATCC_199 LLWNVLVFVLLIVVDRRFKIGHGRLFAMYVAAYCVGRFCVELMR-VDPAT MSMEG_3222|M.smegmatis_MC2_155 LIWNIAVFGFLIWVDRKFRIGHGRLFALYVASYCVGRFWVELMR-SDTAT TH_1073|M.thermoresistible__bu MLWNVLVFVVLIWADRRFRLGHGRLFALYVAGYCVGRFWVELLR-SDFAT Mflv_3597|M.gilvum_PYR-GCK LLWNLLVFAVLILVDRRFKIGHGRLFALYVAGYCAGRFWIELMR-SDTAT Mvan_2819|M.vanbaalenii_PYR-1 LLWNLLVFAVLILVDRRFKIGHGRLFALYVAGYCVGRFWIELMR-SDTAT MUL_3715|M.ulcerans_Agy99 PPHPGSRYTQIAVLEDGIVVEH--FVTSAASASLVGNIYLGIVQNVLPSM : : : : : * :. .: *.: : ::: : MMAR_2416|M.marinum_M HIAGIRINSFTSTFVFIGAVVYIILAP--KGREDPASVRGTAAAAEEVPE MLBr_01274|M.leprae_Br4923 HIAGIRINSFTSTFVFIGAVVYIILAP--KGREEPENLCRAEYVAREIPE Mb1640|M.bovis_AF2122/97 LIAGIRINSFTSTFVFIGAVVYIILAP--KGREAPGALRGSEYVVDEALE Rv1614|M.tuberculosis_H37Rv LIAGIRINSFTSTFVFIGAVVYIILAP--KGREAPGALRGSEYVVDEALE MAV_3172|M.avium_104 HIAGIRINSFTSTFVFIGAVVYLMAAP--KGREDPESLRGNQYVEEEPAE MAB_2642c|M.abscessus_ATCC_199 QFGGIRVNSFTSTLVFVGAVAYILLAP--KGREDPATLGG-TPSSADGGD MSMEG_3222|M.smegmatis_MC2_155 EFAGIRVNTFTSTFVFIGAVVYIMLAP--KGREEPESLRGKAADETEEGD TH_1073|M.thermoresistible__bu HIAGIRINSFTASFVFIGAVVYIMVAP--KGREDPATLGG--PVQTDAGA Mflv_3597|M.gilvum_PYR-GCK LLAGIRVNTFTATFVFVAAVVYVIVAP--KGREAPESLRGNQDAESDVED Mvan_2819|M.vanbaalenii_PYR-1 LLAGIRVNSFTSTFVFIGAVVYIMAAP--KGREDPSSLKGNQDAEARVED MUL_3715|M.ulcerans_Agy99 EAAFVDIGRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYIVVQVSK . : :. .:: . * : . .*: : MMAR_2416|M.marinum_M PEP-----------------AGEVATAAAPAGDTEGDEPTGLAETAKAAE MLBr_01274|M.leprae_Br4923 PES-----------------ATERATVAS--------------------- Mb1640|M.bovis_AF2122/97 REP-----------------AELAAAAVAS-------------------- Rv1614|M.tuberculosis_H37Rv REP-----------------AELAAAAVAS-------------------- MAV_3172|M.avium_104 PEP-----------------ATVAATTEAA-------------------- MAB_2642c|M.abscessus_ATCC_199 D----------------------TAETEAT-------------------- MSMEG_3222|M.smegmatis_MC2_155 EESLVDEAGKELVAAAAGTGVVAAATAAAR-------------------- TH_1073|M.thermoresistible__bu DTG--------------------AAGADAE-------------------- Mflv_3597|M.gilvum_PYR-GCK LAKDVALASAVG--------VVAAATVAGEDEKRDGG-------GSPPGG Mvan_2819|M.vanbaalenii_PYR-1 LAKDVAVGSATG--------IVAAATVADEDE------------AMEPAD MUL_3715|M.ulcerans_Agy99 DPVGHKGARLTTQVSLAGRYLVYVAGASSTGISRKLPDTERQRLKEILRE * . MMAR_2416|M.marinum_M VAEPETVGSAVAGDEST-ADTEASDAVE--------SEVGEAAEAEAPEA MLBr_01274|M.leprae_Br4923 -TYATTTAVPVSADEEF-AETN---------------------------- Mb1640|M.bovis_AF2122/97 ---AASAVGPVGPGEPN-QPDDVAEAVK--------AEVAEVTDEVAAES Rv1614|M.tuberculosis_H37Rv ---AASAVGPVGPGEPN-QPDDVAEAVK--------AEVAEVTDEVAAES MAV_3172|M.avium_104 ---TEGVAAPADGAEAAGADATAQRPEE--------SAEPDVEKPESEET MAB_2642c|M.abscessus_ATCC_199 -ADTEDTEDTED--GVTDAP--EAD--------------ATDKSVDESAD MSMEG_3222|M.smegmatis_MC2_155 -EDTDDTDGTTDPAAASDEPGDEAEPETEAATAVLTADGAEAMSVDEQPD TH_1073|M.thermoresistible__bu -VDTEVDTEKEDVAAAVRGVAGAGAXX------------XRHIARRRGRR Mflv_3597|M.gilvum_PYR-GCK LGSVEGDEALEAAGGASAANESAVEGAADAADLVALLEASEDVEVADGAV Mvan_2819|M.vanbaalenii_PYR-1 DDDAAEVEALVAELEASEP-ETEGLGSVEGDEVAEAVEVAP--EVHEAAV MUL_3715|M.ulcerans_Agy99 VVPSDAGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKAVEIKQKAAGA MMAR_2416|M.marinum_M EAEEAEVGEVEVAEAVEGEVEEAEEAEPGEVEVAEAVEGEVEAAAEAEEA MLBr_01274|M.leprae_Br4923 -------------------------------------------------- Mb1640|M.bovis_AF2122/97 VVQVADR--------------------------------------DGEST Rv1614|M.tuberculosis_H37Rv VVQVADR--------------------------------------DGEST MAV_3172|M.avium_104 EAEAAEE-------------------------------------PESEET MAB_2642c|M.abscessus_ATCC_199 NSGIVEK------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 DDEAVDEEAGQEAEEPADELVELADEPEGEPEPAAAEEAEPAETIEPDED TH_1073|M.thermoresistible__bu RGERIRRRR---------------------------------------RR Mflv_3597|M.gilvum_PYR-GCK EPQEVDAPPVPDEAGGLGAVEGEEAAEAAAGAGAARASVSDDAEASNDAD Mvan_2819|M.vanbaalenii_PYR-1 EG-EAEAEELASDVEGAPEPEGVEAAEAEAESPVDGAEAESEVVEG-DVE MUL_3715|M.ulcerans_Agy99 AVALYEEPDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVS MMAR_2416|M.marinum_M EEAEEAEE-----AEEAEEAEPGEIEVAEAVEGEVEAAAEAEEAEVGEVE MLBr_01274|M.leprae_Br4923 -------------------------------------------------- Mb1640|M.bovis_AF2122/97 PAVEETSE-----ADIERE-QPGDLAGQAPAAHQVDAEAASAAPEE---- Rv1614|M.tuberculosis_H37Rv PAVEETSE-----ADIERE-QPGDLAGQAPAAHQVDAEAASAAPEE---- MAV_3172|M.avium_104 EAAEEPGE-----PEAEEPEEPEAEEPEEPETEEPEADSDEEPEEE---- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 EIFDAELA-----EALAEAAEDFAVVPESAGSDEAEVAAAESAADAEDGP TH_1073|M.thermoresistible__bu QLVDRRRV-----QWLRRG-----IVHHIARGRAGQHLAAG--------- Mflv_3597|M.gilvum_PYR-GCK AETEAAGLGSVDGDEVAAAVEDAPEVHEAAVEGEAEAEELAAEAEVEAVA Mvan_2819|M.vanbaalenii_PYR-1 SVTESEGLGSVEGDEVAEAVEVAPEVHEVVVEGEAEAEALAADAEAEAEA MUL_3715|M.ulcerans_Agy99 KLSKYEPAVGSEGQVGPDVFAVHRIDEHLAKAMDRKVWLPSGGTLVIDRT MMAR_2416|M.marinum_M AVDEAAEAEAPEVGEIEAAEAVEGEVEVAAEAEEAEAGEDEPKEAEEV-- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- Mb1640|M.bovis_AF2122/97 -------------------------------------------------- Rv1614|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 SDAESAEVPAEAAADDAVVSEPAGTVDETEVAEEAAAEAADLEFESYD-- TH_1073|M.thermoresistible__bu -------------------------------RPRPLALAGQHPLGDRD-- Mflv_3597|M.gilvum_PYR-GCK AEVAEVDADALTGADDDVDAETEAAVEGEAEAEELAAEADAEAQVAAE-V Mvan_2819|M.vanbaalenii_PYR-1 ----EAEAEDLA-ADVEAESPVDGAED-ESEAESEVVEGDVESVTESEGL MUL_3715|M.ulcerans_Agy99 EAMTVVDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVI MMAR_2416|M.marinum_M -------------------AEAEGSEAEDKTVQAIDGGQTGVDDAGEADA MLBr_01274|M.leprae_Br4923 -------------------------------------------------- Mb1640|M.bovis_AF2122/97 -------------------PAALASEAHDET------------------- Rv1614|M.tuberculosis_H37Rv -------------------PAALASEAHDET------------------- MAV_3172|M.avium_104 -----------------------SGEAPEQP------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------AELAEALAEAAE------------------- TH_1073|M.thermoresistible__bu -------------------LLLLGGQVGVRR------------------- Mflv_3597|M.gilvum_PYR-GCK AEVDADALTGADDDVDAETEAEVEGEAEAEELAAEAD-AEAQVAAEVAEV Mvan_2819|M.vanbaalenii_PYR-1 GSVEGDEVAEAVEVAPEVHEAAVEGEAEAEELASDVEGAPEPEGVEAAEA MUL_3715|M.ulcerans_Agy99 DFIDMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLGLVQLTRKRLGTG MMAR_2416|M.marinum_M EPDD---------------------------------DSTAAEPEVVVEQ MLBr_01274|M.leprae_Br4923 -------------------------------------------------- Mb1640|M.bovis_AF2122/97 ------------------------------------------EPEVPEKA Rv1614|M.tuberculosis_H37Rv ------------------------------------------EPEVPEKA MAV_3172|M.avium_104 ---------------------------------------------VAEEP MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 --------------------------------------------DMAVVV TH_1073|M.thermoresistible__bu --------------------------------------------ELAAAV Mflv_3597|M.gilvum_PYR-GCK DAET-LTGADKDVDAEALT-DADAETEAAG-------LGSVDGDEVAAAV Mvan_2819|M.vanbaalenii_PYR-1 EAESPVDGAEAEAESEVVEGDVESVTESEG-------LGSVEGDEVAEAV MUL_3715|M.ulcerans_Agy99 LIEAFSTSCPHCSGRGILLHADPVDSAPTTGRKADSGGRRNRRSKKNRAE MMAR_2416|M.marinum_M ADIEEIEPQEPEAEAVAAAEATDADEGDGEPAEPASDDLDAVAAEDADVD MLBr_01274|M.leprae_Br4923 -------------------------------------------------- Mb1640|M.bovis_AF2122/97 APIP--DPAKPDELAVAG-------------------------------- Rv1614|M.tuberculosis_H37Rv APIP--DPAKPDELAVAG-------------------------------- MAV_3172|M.avium_104 EPAP----QQPE-------------------------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 APAETAESDEAREPVETD-------------------------------- TH_1073|M.thermoresistible__bu GPPGAGSELQAPVIAVTG-------------------------------- Mflv_3597|M.gilvum_PYR-GCK EDAPEVHEAAVEGESEAEELAAEADAEALAEVAEIDAEAVNDADED---- Mvan_2819|M.vanbaalenii_PYR-1 EVAPEVHEVVVEGEAEAEALAADADADADAEAEDLAADVEAESPVDGAED MUL_3715|M.ulcerans_Agy99 EPSEKEAVAKVPTYAPGEHPMFKAMAASSSSEAEHGDGEVEESGEELTAA MMAR_2416|M.marinum_M VDATATEAEESGDESPEPAADSEEPEADESAPEDSAEDTSSGESDTQSEL MLBr_01274|M.leprae_Br4923 -------------------------------------------------- Mb1640|M.bovis_AF2122/97 -----------------PGDDPAEPDG----------------------- Rv1614|M.tuberculosis_H37Rv -----------------PGDDPAEPDG----------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 ---------ATESEEPSEPEEPDAPEA----------------------- TH_1073|M.thermoresistible__bu ---------VDGPVSARLATGDLIPFG----------------------- Mflv_3597|M.gilvum_PYR-GCK ----------VDAEAEAEAAGLGSVDGDEVAAAVEDAPEVREAVEG---- Mvan_2819|M.vanbaalenii_PYR-1 ESEAEPEAVEGDVESVTESEGLGSVEGDEAAEAEELVGEVEADVEAETGE MUL_3715|M.ulcerans_Agy99 VDDQTAVQVALDLGETEESEETDGTDETDDFDDDSDDSDDSDEDDDTDET MMAR_2416|M.marinum_M EQSQTIEQGSDQTSAGDG-------------------------------- MLBr_01274|M.leprae_Br4923 -------------------------------------------------- Mb1640|M.bovis_AF2122/97 -----IRRQDDFSS------------------------------------ Rv1614|M.tuberculosis_H37Rv -----IRRQDDFSS------------------------------------ MAV_3172|M.avium_104 -------------------------------------------------- MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 ------VEAPEALDENAD-------------------------------- TH_1073|M.thermoresistible__bu ------VGG----------------------------------------- Mflv_3597|M.gilvum_PYR-GCK -----VAEVDAEALTDAE-------------------------------- Mvan_2819|M.vanbaalenii_PYR-1 AAADEVAEVDAGAVTDTDDDAEGLGSVEGDEVAESAEDASEVHEAAVERE MUL_3715|M.ulcerans_Agy99 NDTDVDADEDEDTDDDSDE------------------------------- MMAR_2416|M.marinum_M ----------------------------EGPPPSAAVDGDTGPTRQGWRG MLBr_01274|M.leprae_Br4923 -------------------------------------------------- Mb1640|M.bovis_AF2122/97 ------------------------------------------RRRRWWRL Rv1614|M.tuberculosis_H37Rv ------------------------------------------RRRRWWRL MAV_3172|M.avium_104 -------------------------------------------TKRRWGA MAB_2642c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 ----------------------------ETRAEPAAPAAVATAPVEPEKG TH_1073|M.thermoresistible__bu ------------------------------RTGLTGHRQAATAEHSPGDS Mflv_3597|M.gilvum_PYR-GCK --PEESDAEGEPEGPALP------TSEHSPYTVVT--ESSSEPAQSGPAG Mvan_2819|M.vanbaalenii_PYR-1 EAAEERAAEAEADDASEPQPEEAADTEPAADGAVTRVESRSVATESQSGG MUL_3715|M.ulcerans_Agy99 --DEDTEDDDELDDDLDDELDDDDSDSDDEDSESELTEPAAGRPAALEVT MMAR_2416|M.marinum_M RLRNRMRRSGR------------ MLBr_01274|M.leprae_Br4923 ----------------------- Mb1640|M.bovis_AF2122/97 RRRRQ------------------ Rv1614|M.tuberculosis_H37Rv RRRRQ------------------ MAV_3172|M.avium_104 RLRDRLSGR-------------- MAB_2642c|M.abscessus_ATCC_199 ----------------------- MSMEG_3222|M.smegmatis_MC2_155 RLRRWLRRNR------------- TH_1073|M.thermoresistible__bu DFRDVYG---------------- Mflv_3597|M.gilvum_PYR-GCK LVRQWIRRRRNR----------- Mvan_2819|M.vanbaalenii_PYR-1 LLRRMLRRRRSR----------- MUL_3715|M.ulcerans_Agy99 TIAERPRRRRAAGRPAGPPIHLG