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M. marinum M MMAR_2416 (lgt)

annotation: prolipoprotein diacylglyceryl transferases Lgt
coordinates: 2914939 - 2917083
length: 714

MTATVLAYFPSPPRGVWHLGPLPIRAYAFFIIIGIVMGLMIGDRRFAARGGERGVIYDIALWMVPFGLIG
GRLYHLSTDWQTYFGEGGAGLGAALRIWDGGLGIWGAVTLGTVGAWIGCRRRGIPLPAFLDAVAPGVVMG
QAIGRLGNYFNQELYGRETTVPWGLEIFYRRDPSGFVDVHSLDGVSTGQVAVVVQPTFLYELIWNLLVFA
ALIYLDRRFTIGHGRLFASYVALYCVGRFCVELLRDDTATHIAGIRINSFTSTFVFIGAVVYIILAPKGR
EDPASVRGTAAAAEEVPEPEPAGEVATAAAPAGDTEGDEPTGLAETAKAAEVAEPETVGSAVAGDESTAD
TEASDAVESEVGEAAEAEAPEAEAEEAEVGEVEVAEAVEGEVEEAEEAEPGEVEVAEAVEGEVEAAAEAE
EAEEAEEAEEAEEAEEAEPGEIEVAEAVEGEVEAAAEAEEAEVGEVEAVDEAAEAEAPEVGEIEAAEAVE
GEVEVAAEAEEAEAGEDEPKEAEEVAEAEGSEAEDKTVQAIDGGQTGVDDAGEADAEPDDDSTAAEPEVV
VEQADIEEIEPQEPEAEAVAAAEATDADEGDGEPAEPASDDLDAVAAEDADVDVDATATEAEESGDESPE
PAADSEEPEADESAPEDSAEDTSSGESDTQSELEQSQTIEQGSDQTSAGDGEGPPPSAAVDGDTGPTRQG
WRGRLRNRMRRSGR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2416lgt-100% (714)prolipoprotein diacylglyceryl transferases Lgt
M. marinum MMMAR_5242-8e-1050.00% (88) hypothetical protein MMAR_5242
M. marinum MMMAR_3768rne8e-1023.27% (275) ribonuclease E Rne

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1640lgt1e-15362.44% (450) prolipoprotein diacylglyceryl transferase
M. gilvum PYR-GCKMflv_3597-1e-16547.17% (778) prolipoprotein diacylglyceryl transferase
M. tuberculosis H37RvRv1614lgt1e-15362.44% (450) prolipoprotein diacylglyceryl transferase
M. leprae Br4923MLBr_01274-1e-14676.51% (315) putative prolipoprotein diacylglyceryl transferase
M. abscessus ATCC 19977MAB_2642c-1e-13261.01% (377) prolipoprotein diacylglyceryl transferase
M. avium 104MAV_3172-1e-16567.20% (439) prolipoprotein diacylglyceryl transferase
M. smegmatis MC2 155MSMEG_3222-1e-15451.70% (617) prolipoprotein diacylglyceryl transferase
M. thermoresistible (build 8)TH_1073lgt1e-12768.10% (326) Possible prolipoprotein diacylglyceryl transferases Lgt
M. ulcerans Agy99MUL_3715rne4e-1026.98% (189) ribonuclease E Rne
M. vanbaalenii PYR-1Mvan_2819-1e-16950.69% (726) prolipoprotein diacylglyceryl transferase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2416|M.marinum_M               MTATVLAYFPSPPRGVWHLGPLPIRAYAFFIIIG----------------
MLBr_01274|M.leprae_Br4923          MTRMLPGYFPSPPRGVWHLGPLPIRAYALLIILG----------------
Mb1640|M.bovis_AF2122/97            -MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITG----------------
Rv1614|M.tuberculosis_H37Rv         -MRMLPSYIPSPPRGVWYLGPLPVRAYAVCVITG----------------
MAV_3172|M.avium_104                -MTKLLAYFPSPPQGVWHLGPVPIRAYALFIIAG----------------
MAB_2642c|M.abscessus_ATCC_199      MTVVNLAYIPSPPQGVWHLGPIPIRAYALCIIAG----------------
MSMEG_3222|M.smegmatis_MC2_155      MTTTVLAYLPSPSQGVWHLGPVPIRAYALCIIVG----------------
TH_1073|M.thermoresistible__bu      -VTTTLAYIPSPAQGVWQLGPIPIRAYALCIIAG----------------
Mflv_3597|M.gilvum_PYR-GCK          MTTTVLAYIPSPPQGVWYLGPFPLRAYALCIIVG----------------
Mvan_2819|M.vanbaalenii_PYR-1       MTTTVLAYIPSPSQGVWHLGPFPVRAYALFIIVG----------------
MUL_3715|M.ulcerans_Agy99           MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR
                                          .  *.         *  :*.::.    *                

MMAR_2416|M.marinum_M               --------------IVMGLMIGDRRFAARGGERGVIYDIALWMVPFG---
MLBr_01274|M.leprae_Br4923          --------------IVAALVVGGRCWEARGGERDVTYDIALWAVPFG---
Mb1640|M.bovis_AF2122/97            --------------IIVALLIGDRRLTARGGERGMTYDIALWAVPFG---
Rv1614|M.tuberculosis_H37Rv         --------------IIVALLIGDRRLTARGGERGMTYDIALWAVPFG---
MAV_3172|M.avium_104                --------------IVAALLIGDRRWEARGGERGVIYDIALWTVPFG---
MAB_2642c|M.abscessus_ATCC_199      --------------IVAALIIGDRRWEQRGGERGVIYDIALWAVPFG---
MSMEG_3222|M.smegmatis_MC2_155      --------------IVAALVIGDRRWQARGGEPGVIYDIALWAVPFG---
TH_1073|M.thermoresistible__bu      --------------IVVALVLGDRRWAARGGERGVIYDIALWAVPFG---
Mflv_3597|M.gilvum_PYR-GCK          --------------IVAALVIGDRRWVARGGEPGVIYDIALWAVPFG---
Mvan_2819|M.vanbaalenii_PYR-1       --------------IIAALVIGDRRWVARGGESGVIYDIALWAVPFG---
MUL_3715|M.ulcerans_Agy99           IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEDQQAPDAVAAEVPDAPGE
                                                   :  *:        :. *     * .   ** .   

MMAR_2416|M.marinum_M               ---------LIGGRLYHLSTDWQT--------------------------
MLBr_01274|M.leprae_Br4923          ---------LVGGRLYHLATDWRT--------------------------
Mb1640|M.bovis_AF2122/97            ---------LIGGRLYHLATDWRT--------------------------
Rv1614|M.tuberculosis_H37Rv         ---------LIGGRLYHLATDWRT--------------------------
MAV_3172|M.avium_104                ---------LVGGRLYHLATDWRT--------------------------
MAB_2642c|M.abscessus_ATCC_199      ---------LVGGRLYHVMTDWQT--------------------------
MSMEG_3222|M.smegmatis_MC2_155      ---------LAGGRIYHVITDWKT--------------------------
TH_1073|M.thermoresistible__bu      ---------LIGGRVYHVLTDWRT--------------------------
Mflv_3597|M.gilvum_PYR-GCK          ---------LIGGRLYHVITDWPT--------------------------
Mvan_2819|M.vanbaalenii_PYR-1       ---------LIGGRLYHVITDWPT--------------------------
MUL_3715|M.ulcerans_Agy99           PAEPESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDADDE
                                             *   .  ::   *                            

MMAR_2416|M.marinum_M               --------------------YFGEGGAGLGAALRIWDGGLGIWG------
MLBr_01274|M.leprae_Br4923          --------------------YFGQNGAGLGAALRIWDGGLGIWG------
Mb1640|M.bovis_AF2122/97            --------------------YFGDGGAGLAAALRIWDGGLGIWG------
Rv1614|M.tuberculosis_H37Rv         --------------------YFGDGGAGLAAALRIWDGGLGIWG------
MAV_3172|M.avium_104                --------------------YWGPGGAGFGAAVRIWDGGLGIWG------
MAB_2642c|M.abscessus_ATCC_199      --------------------YFGAHGKGIGKAIAVWEGGLGIWG------
MSMEG_3222|M.smegmatis_MC2_155      --------------------YFGPTGKGFGAALQIWEGGLGIWG------
TH_1073|M.thermoresistible__bu      --------------------YFGPDGAGFVAALRIWDGGLGIWG------
Mflv_3597|M.gilvum_PYR-GCK          --------------------YFGDGGAGPAAALRIWDGGLGIWG------
Mvan_2819|M.vanbaalenii_PYR-1       --------------------YFGEGGAGPAAALRIWDGGLGIWG------
MUL_3715|M.ulcerans_Agy99           SGDEGDDDEEQADRPGNRRRRRGRRGRGRGRGEQGANDGQDQPGDDGDEA
                                                          *  * *   .    :.* .  *      

MMAR_2416|M.marinum_M               -----------------------------AVTLGTVGAWIGCRRRGIPLP
MLBr_01274|M.leprae_Br4923          -----------------------------AVALGCVGAWLGCRRHRIPLP
Mb1640|M.bovis_AF2122/97            -----------------------------AVTLGVMGAWIGCRRCGIPLP
Rv1614|M.tuberculosis_H37Rv         -----------------------------AVTLGVMGAWIGCRRCGIPLP
MAV_3172|M.avium_104                -----------------------------AVALGAVGAWIGCRRHGIPLP
MAB_2642c|M.abscessus_ATCC_199      -----------------------------AVALGGVGAWIACRRRGIPLP
MSMEG_3222|M.smegmatis_MC2_155      -----------------------------AVAFGAVGAWIACRLRGIPLP
TH_1073|M.thermoresistible__bu      -----------------------------AVALGGVGAWIACRRHGIPLP
Mflv_3597|M.gilvum_PYR-GCK          -----------------------------AVALGAVGAWIACRRRGIPLP
Mvan_2819|M.vanbaalenii_PYR-1       -----------------------------AVALGGIGAWIACRRRGIPLP
MUL_3715|M.ulcerans_Agy99           PQKAGGNSTSSDDSEAQDGADSEESDNGDDDNGSADGASRRRRRRRRRKS
                                                                     .  **    *      .

MMAR_2416|M.marinum_M               AFLDAVAPG--------VVMGQAIGRLGNYFN----------QELYGRET
MLBr_01274|M.leprae_Br4923          AFGDALAPG--------IILAQAIGRLGNYFN----------QELYGRET
Mb1640|M.bovis_AF2122/97            VLLDAVAPG--------VVLAQAIGRLGNYFN----------QELYGRET
Rv1614|M.tuberculosis_H37Rv         VLLDAVAPG--------VVLAQAIGRLGNYFN----------QELYGRET
MAV_3172|M.avium_104                AFADALAPG--------IILAQAIGRLGNYFN----------QELYGRET
MAB_2642c|M.abscessus_ATCC_199      AFADAIAPG--------IVLAQAIGRLGNYFN----------QELTGGPT
MSMEG_3222|M.smegmatis_MC2_155      AFGDAIAPG--------IILAQGIGRLGNYFN----------QELYGRPT
TH_1073|M.thermoresistible__bu      AFGDAIAPG--------IVLAQAIGRLGNYFN----------QELYGRPT
Mflv_3597|M.gilvum_PYR-GCK          AFGDAIAPG--------IVLAQAIGRLGNYFN----------QELYGRET
Mvan_2819|M.vanbaalenii_PYR-1       AFGDAIAPG--------IVLAQAIGRLGNYFN----------QELFGRET
MUL_3715|M.ulcerans_Agy99           GAGDDGDEGPAPDDPPNTVVHERAPRSGDKSGNSDSGDDSGGNEIKGIDG
                                       *    *         :: :   * *:  .          :*: *   

MMAR_2416|M.marinum_M               TVPWGLEIFYRRD--------PSGFVDVHSLDGVSTGQVAVVVQPTFLYE
MLBr_01274|M.leprae_Br4923          TMPWGLEVFYRRD--------PAGYMDPHSLDGVSTGQLAFVVQPTFLYE
Mb1640|M.bovis_AF2122/97            TMPWGLEIFYRRD--------PSGFDVPNSLDGVSTGQVAFVVQPTFLYE
Rv1614|M.tuberculosis_H37Rv         TMPWGLEIFYRRD--------PSGFDVPNSLDGVSTGQVAFVVQPTFLYE
MAV_3172|M.avium_104                TLPWGLEIFYRRD--------PSGYIDPHSLDGVSTGQVALVVQPTFLYE
MAB_2642c|M.abscessus_ATCC_199      TLPWGLELFYRRS--------ADGTVDVLNLNGVSTGEVAQVVHPTFLYE
MSMEG_3222|M.smegmatis_MC2_155      DVPWGLEIYERLN--------KFGQSD--QLNGVSTGQVTAVVHPTFLYE
TH_1073|M.thermoresistible__bu      TLPWGLEIYERRN--------ASGALD--PLNGTSTGELLAVVHPTFLYE
Mflv_3597|M.gilvum_PYR-GCK          TVPWGLEIYERRN--------SAGVLD--SLNGISTGELIGVVHPTFLYE
Mvan_2819|M.vanbaalenii_PYR-1       TVPWGLEIYERVN--------AAGVPD--SLNGVSTGELIQVVHPTFLYE
MUL_3715|M.ulcerans_Agy99           STRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTE
                                          :   * .                 *   .: :   **:  .  *

MMAR_2416|M.marinum_M               LIWNLLVFAALIYLDRRFTIGHGRLFASYVALYCVGRFCVELLR-DDTAT
MLBr_01274|M.leprae_Br4923          LIWNVLVFFALIYVDRWFTLGHGRLFATYVAAYCIGRFCVELLR-DDAAT
Mb1640|M.bovis_AF2122/97            LIWNVLVFVALIYIDRRFIIGHGRLFGFYVAFYCAGRFCVELLR-DDPAT
Rv1614|M.tuberculosis_H37Rv         LIWNVLVFVALIYIDRRFIIGHGRLFGFYVAFYCAGRFCVELLR-DDPAT
MAV_3172|M.avium_104                LLWNLLIFVALLYADRRLTLGHGRLFALYVAGYCVGRFCVELLR-DDTAT
MAB_2642c|M.abscessus_ATCC_199      LLWNVLVFVLLIVVDRRFKIGHGRLFAMYVAAYCVGRFCVELMR-VDPAT
MSMEG_3222|M.smegmatis_MC2_155      LIWNIAVFGFLIWVDRKFRIGHGRLFALYVASYCVGRFWVELMR-SDTAT
TH_1073|M.thermoresistible__bu      MLWNVLVFVVLIWADRRFRLGHGRLFALYVAGYCVGRFWVELLR-SDFAT
Mflv_3597|M.gilvum_PYR-GCK          LLWNLLVFAVLILVDRRFKIGHGRLFALYVAGYCAGRFWIELMR-SDTAT
Mvan_2819|M.vanbaalenii_PYR-1       LLWNLLVFAVLILVDRRFKIGHGRLFALYVAGYCVGRFWIELMR-SDTAT
MUL_3715|M.ulcerans_Agy99           PPHPGSRYTQIAVLEDGIVVEH--FVTSAASASLVGNIYLGIVQNVLPSM
                                           :  :   :  : : *  :.   .:    *.: : :::    : 

MMAR_2416|M.marinum_M               HIAGIRINSFTSTFVFIGAVVYIILAP--KGREDPASVRGTAAAAEEVPE
MLBr_01274|M.leprae_Br4923          HIAGIRINSFTSTFVFIGAVVYIILAP--KGREEPENLCRAEYVAREIPE
Mb1640|M.bovis_AF2122/97            LIAGIRINSFTSTFVFIGAVVYIILAP--KGREAPGALRGSEYVVDEALE
Rv1614|M.tuberculosis_H37Rv         LIAGIRINSFTSTFVFIGAVVYIILAP--KGREAPGALRGSEYVVDEALE
MAV_3172|M.avium_104                HIAGIRINSFTSTFVFIGAVVYLMAAP--KGREDPESLRGNQYVEEEPAE
MAB_2642c|M.abscessus_ATCC_199      QFGGIRVNSFTSTLVFVGAVAYILLAP--KGREDPATLGG-TPSSADGGD
MSMEG_3222|M.smegmatis_MC2_155      EFAGIRVNTFTSTFVFIGAVVYIMLAP--KGREEPESLRGKAADETEEGD
TH_1073|M.thermoresistible__bu      HIAGIRINSFTASFVFIGAVVYIMVAP--KGREDPATLGG--PVQTDAGA
Mflv_3597|M.gilvum_PYR-GCK          LLAGIRVNTFTATFVFVAAVVYVIVAP--KGREAPESLRGNQDAESDVED
Mvan_2819|M.vanbaalenii_PYR-1       LLAGIRVNSFTSTFVFIGAVVYIMAAP--KGREDPSSLKGNQDAEARVED
MUL_3715|M.ulcerans_Agy99           EAAFVDIGRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYIVVQVSK
                                      . : :.     .:: . * :   .    .*:    :            

MMAR_2416|M.marinum_M               PEP-----------------AGEVATAAAPAGDTEGDEPTGLAETAKAAE
MLBr_01274|M.leprae_Br4923          PES-----------------ATERATVAS---------------------
Mb1640|M.bovis_AF2122/97            REP-----------------AELAAAAVAS--------------------
Rv1614|M.tuberculosis_H37Rv         REP-----------------AELAAAAVAS--------------------
MAV_3172|M.avium_104                PEP-----------------ATVAATTEAA--------------------
MAB_2642c|M.abscessus_ATCC_199      D----------------------TAETEAT--------------------
MSMEG_3222|M.smegmatis_MC2_155      EESLVDEAGKELVAAAAGTGVVAAATAAAR--------------------
TH_1073|M.thermoresistible__bu      DTG--------------------AAGADAE--------------------
Mflv_3597|M.gilvum_PYR-GCK          LAKDVALASAVG--------VVAAATVAGEDEKRDGG-------GSPPGG
Mvan_2819|M.vanbaalenii_PYR-1       LAKDVAVGSATG--------IVAAATVADEDE------------AMEPAD
MUL_3715|M.ulcerans_Agy99           DPVGHKGARLTTQVSLAGRYLVYVAGASSTGISRKLPDTERQRLKEILRE
                                                            * .                       

MMAR_2416|M.marinum_M               VAEPETVGSAVAGDEST-ADTEASDAVE--------SEVGEAAEAEAPEA
MLBr_01274|M.leprae_Br4923          -TYATTTAVPVSADEEF-AETN----------------------------
Mb1640|M.bovis_AF2122/97            ---AASAVGPVGPGEPN-QPDDVAEAVK--------AEVAEVTDEVAAES
Rv1614|M.tuberculosis_H37Rv         ---AASAVGPVGPGEPN-QPDDVAEAVK--------AEVAEVTDEVAAES
MAV_3172|M.avium_104                ---TEGVAAPADGAEAAGADATAQRPEE--------SAEPDVEKPESEET
MAB_2642c|M.abscessus_ATCC_199      -ADTEDTEDTED--GVTDAP--EAD--------------ATDKSVDESAD
MSMEG_3222|M.smegmatis_MC2_155      -EDTDDTDGTTDPAAASDEPGDEAEPETEAATAVLTADGAEAMSVDEQPD
TH_1073|M.thermoresistible__bu      -VDTEVDTEKEDVAAAVRGVAGAGAXX------------XRHIARRRGRR
Mflv_3597|M.gilvum_PYR-GCK          LGSVEGDEALEAAGGASAANESAVEGAADAADLVALLEASEDVEVADGAV
Mvan_2819|M.vanbaalenii_PYR-1       DDDAAEVEALVAELEASEP-ETEGLGSVEGDEVAEAVEVAP--EVHEAAV
MUL_3715|M.ulcerans_Agy99           VVPSDAGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKAVEIKQKAAGA
                                                                                      

MMAR_2416|M.marinum_M               EAEEAEVGEVEVAEAVEGEVEEAEEAEPGEVEVAEAVEGEVEAAAEAEEA
MLBr_01274|M.leprae_Br4923          --------------------------------------------------
Mb1640|M.bovis_AF2122/97            VVQVADR--------------------------------------DGEST
Rv1614|M.tuberculosis_H37Rv         VVQVADR--------------------------------------DGEST
MAV_3172|M.avium_104                EAEAAEE-------------------------------------PESEET
MAB_2642c|M.abscessus_ATCC_199      NSGIVEK-------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      DDEAVDEEAGQEAEEPADELVELADEPEGEPEPAAAEEAEPAETIEPDED
TH_1073|M.thermoresistible__bu      RGERIRRRR---------------------------------------RR
Mflv_3597|M.gilvum_PYR-GCK          EPQEVDAPPVPDEAGGLGAVEGEEAAEAAAGAGAARASVSDDAEASNDAD
Mvan_2819|M.vanbaalenii_PYR-1       EG-EAEAEELASDVEGAPEPEGVEAAEAEAESPVDGAEAESEVVEG-DVE
MUL_3715|M.ulcerans_Agy99           AVALYEEPDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVS
                                                                                      

MMAR_2416|M.marinum_M               EEAEEAEE-----AEEAEEAEPGEIEVAEAVEGEVEAAAEAEEAEVGEVE
MLBr_01274|M.leprae_Br4923          --------------------------------------------------
Mb1640|M.bovis_AF2122/97            PAVEETSE-----ADIERE-QPGDLAGQAPAAHQVDAEAASAAPEE----
Rv1614|M.tuberculosis_H37Rv         PAVEETSE-----ADIERE-QPGDLAGQAPAAHQVDAEAASAAPEE----
MAV_3172|M.avium_104                EAAEEPGE-----PEAEEPEEPEAEEPEEPETEEPEADSDEEPEEE----
MAB_2642c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      EIFDAELA-----EALAEAAEDFAVVPESAGSDEAEVAAAESAADAEDGP
TH_1073|M.thermoresistible__bu      QLVDRRRV-----QWLRRG-----IVHHIARGRAGQHLAAG---------
Mflv_3597|M.gilvum_PYR-GCK          AETEAAGLGSVDGDEVAAAVEDAPEVHEAAVEGEAEAEELAAEAEVEAVA
Mvan_2819|M.vanbaalenii_PYR-1       SVTESEGLGSVEGDEVAEAVEVAPEVHEVVVEGEAEAEALAADAEAEAEA
MUL_3715|M.ulcerans_Agy99           KLSKYEPAVGSEGQVGPDVFAVHRIDEHLAKAMDRKVWLPSGGTLVIDRT
                                                                                      

MMAR_2416|M.marinum_M               AVDEAAEAEAPEVGEIEAAEAVEGEVEVAAEAEEAEAGEDEPKEAEEV--
MLBr_01274|M.leprae_Br4923          --------------------------------------------------
Mb1640|M.bovis_AF2122/97            --------------------------------------------------
Rv1614|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
MAB_2642c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      SDAESAEVPAEAAADDAVVSEPAGTVDETEVAEEAAAEAADLEFESYD--
TH_1073|M.thermoresistible__bu      -------------------------------RPRPLALAGQHPLGDRD--
Mflv_3597|M.gilvum_PYR-GCK          AEVAEVDADALTGADDDVDAETEAAVEGEAEAEELAAEADAEAQVAAE-V
Mvan_2819|M.vanbaalenii_PYR-1       ----EAEAEDLA-ADVEAESPVDGAED-ESEAESEVVEGDVESVTESEGL
MUL_3715|M.ulcerans_Agy99           EAMTVVDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVI
                                                                                      

MMAR_2416|M.marinum_M               -------------------AEAEGSEAEDKTVQAIDGGQTGVDDAGEADA
MLBr_01274|M.leprae_Br4923          --------------------------------------------------
Mb1640|M.bovis_AF2122/97            -------------------PAALASEAHDET-------------------
Rv1614|M.tuberculosis_H37Rv         -------------------PAALASEAHDET-------------------
MAV_3172|M.avium_104                -----------------------SGEAPEQP-------------------
MAB_2642c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      -------------------AELAEALAEAAE-------------------
TH_1073|M.thermoresistible__bu      -------------------LLLLGGQVGVRR-------------------
Mflv_3597|M.gilvum_PYR-GCK          AEVDADALTGADDDVDAETEAEVEGEAEAEELAAEAD-AEAQVAAEVAEV
Mvan_2819|M.vanbaalenii_PYR-1       GSVEGDEVAEAVEVAPEVHEAAVEGEAEAEELASDVEGAPEPEGVEAAEA
MUL_3715|M.ulcerans_Agy99           DFIDMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLGLVQLTRKRLGTG
                                                                                      

MMAR_2416|M.marinum_M               EPDD---------------------------------DSTAAEPEVVVEQ
MLBr_01274|M.leprae_Br4923          --------------------------------------------------
Mb1640|M.bovis_AF2122/97            ------------------------------------------EPEVPEKA
Rv1614|M.tuberculosis_H37Rv         ------------------------------------------EPEVPEKA
MAV_3172|M.avium_104                ---------------------------------------------VAEEP
MAB_2642c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      --------------------------------------------DMAVVV
TH_1073|M.thermoresistible__bu      --------------------------------------------ELAAAV
Mflv_3597|M.gilvum_PYR-GCK          DAET-LTGADKDVDAEALT-DADAETEAAG-------LGSVDGDEVAAAV
Mvan_2819|M.vanbaalenii_PYR-1       EAESPVDGAEAEAESEVVEGDVESVTESEG-------LGSVEGDEVAEAV
MUL_3715|M.ulcerans_Agy99           LIEAFSTSCPHCSGRGILLHADPVDSAPTTGRKADSGGRRNRRSKKNRAE
                                                                                      

MMAR_2416|M.marinum_M               ADIEEIEPQEPEAEAVAAAEATDADEGDGEPAEPASDDLDAVAAEDADVD
MLBr_01274|M.leprae_Br4923          --------------------------------------------------
Mb1640|M.bovis_AF2122/97            APIP--DPAKPDELAVAG--------------------------------
Rv1614|M.tuberculosis_H37Rv         APIP--DPAKPDELAVAG--------------------------------
MAV_3172|M.avium_104                EPAP----QQPE--------------------------------------
MAB_2642c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      APAETAESDEAREPVETD--------------------------------
TH_1073|M.thermoresistible__bu      GPPGAGSELQAPVIAVTG--------------------------------
Mflv_3597|M.gilvum_PYR-GCK          EDAPEVHEAAVEGESEAEELAAEADAEALAEVAEIDAEAVNDADED----
Mvan_2819|M.vanbaalenii_PYR-1       EVAPEVHEVVVEGEAEAEALAADADADADAEAEDLAADVEAESPVDGAED
MUL_3715|M.ulcerans_Agy99           EPSEKEAVAKVPTYAPGEHPMFKAMAASSSSEAEHGDGEVEESGEELTAA
                                                                                      

MMAR_2416|M.marinum_M               VDATATEAEESGDESPEPAADSEEPEADESAPEDSAEDTSSGESDTQSEL
MLBr_01274|M.leprae_Br4923          --------------------------------------------------
Mb1640|M.bovis_AF2122/97            -----------------PGDDPAEPDG-----------------------
Rv1614|M.tuberculosis_H37Rv         -----------------PGDDPAEPDG-----------------------
MAV_3172|M.avium_104                --------------------------------------------------
MAB_2642c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      ---------ATESEEPSEPEEPDAPEA-----------------------
TH_1073|M.thermoresistible__bu      ---------VDGPVSARLATGDLIPFG-----------------------
Mflv_3597|M.gilvum_PYR-GCK          ----------VDAEAEAEAAGLGSVDGDEVAAAVEDAPEVREAVEG----
Mvan_2819|M.vanbaalenii_PYR-1       ESEAEPEAVEGDVESVTESEGLGSVEGDEAAEAEELVGEVEADVEAETGE
MUL_3715|M.ulcerans_Agy99           VDDQTAVQVALDLGETEESEETDGTDETDDFDDDSDDSDDSDEDDDTDET
                                                                                      

MMAR_2416|M.marinum_M               EQSQTIEQGSDQTSAGDG--------------------------------
MLBr_01274|M.leprae_Br4923          --------------------------------------------------
Mb1640|M.bovis_AF2122/97            -----IRRQDDFSS------------------------------------
Rv1614|M.tuberculosis_H37Rv         -----IRRQDDFSS------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
MAB_2642c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      ------VEAPEALDENAD--------------------------------
TH_1073|M.thermoresistible__bu      ------VGG-----------------------------------------
Mflv_3597|M.gilvum_PYR-GCK          -----VAEVDAEALTDAE--------------------------------
Mvan_2819|M.vanbaalenii_PYR-1       AAADEVAEVDAGAVTDTDDDAEGLGSVEGDEVAESAEDASEVHEAAVERE
MUL_3715|M.ulcerans_Agy99           NDTDVDADEDEDTDDDSDE-------------------------------
                                                                                      

MMAR_2416|M.marinum_M               ----------------------------EGPPPSAAVDGDTGPTRQGWRG
MLBr_01274|M.leprae_Br4923          --------------------------------------------------
Mb1640|M.bovis_AF2122/97            ------------------------------------------RRRRWWRL
Rv1614|M.tuberculosis_H37Rv         ------------------------------------------RRRRWWRL
MAV_3172|M.avium_104                -------------------------------------------TKRRWGA
MAB_2642c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      ----------------------------ETRAEPAAPAAVATAPVEPEKG
TH_1073|M.thermoresistible__bu      ------------------------------RTGLTGHRQAATAEHSPGDS
Mflv_3597|M.gilvum_PYR-GCK          --PEESDAEGEPEGPALP------TSEHSPYTVVT--ESSSEPAQSGPAG
Mvan_2819|M.vanbaalenii_PYR-1       EAAEERAAEAEADDASEPQPEEAADTEPAADGAVTRVESRSVATESQSGG
MUL_3715|M.ulcerans_Agy99           --DEDTEDDDELDDDLDDELDDDDSDSDDEDSESELTEPAAGRPAALEVT
                                                                                      

MMAR_2416|M.marinum_M               RLRNRMRRSGR------------
MLBr_01274|M.leprae_Br4923          -----------------------
Mb1640|M.bovis_AF2122/97            RRRRQ------------------
Rv1614|M.tuberculosis_H37Rv         RRRRQ------------------
MAV_3172|M.avium_104                RLRDRLSGR--------------
MAB_2642c|M.abscessus_ATCC_199      -----------------------
MSMEG_3222|M.smegmatis_MC2_155      RLRRWLRRNR-------------
TH_1073|M.thermoresistible__bu      DFRDVYG----------------
Mflv_3597|M.gilvum_PYR-GCK          LVRQWIRRRRNR-----------
Mvan_2819|M.vanbaalenii_PYR-1       LLRRMLRRRRSR-----------
MUL_3715|M.ulcerans_Agy99           TIAERPRRRRAAGRPAGPPIHLG