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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3724 | - | - | 100% (432) | putative PE-PPE, C-terminal domain protein |
| M. thermoresistible (build 8) | TH_4029 | - | 1e-33 | 37.50% (288) | PUTATIVE putative PE-PPE, C-terminal domain protein |
| M. thermoresistible (build 8) | TH_4159 | - | 2e-14 | 24.76% (517) | PUTATIVE PE-PPE, C-terminal domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1465 | PE16 | 8e-50 | 36.96% (349) | PE family protein |
| M. gilvum PYR-GCK | Mflv_1918 | - | 3e-45 | 34.65% (456) | hypothetical protein Mflv_1918 |
| M. tuberculosis H37Rv | Rv1430 | PE16 | 8e-50 | 36.96% (349) | PE family protein |
| M. leprae Br4923 | MLBr_01232 | - | 1e-15 | 30.29% (241) | hypothetical protein MLBr_01232 |
| M. abscessus ATCC 19977 | MAB_4141 | - | 2e-43 | 33.75% (397) | PE/PPE family protein |
| M. marinum M | MMAR_2235 | - | 3e-47 | 43.88% (237) | PE-PGRS family protein, PE16 |
| M. avium 104 | MAV_1760 | - | 2e-14 | 29.21% (267) | hypothetical protein MAV_1760 |
| M. smegmatis MC2 155 | MSMEG_5455 | - | 4e-47 | 39.22% (283) | PE family protein |
| M. ulcerans Agy99 | MUL_1034 | - | 8e-45 | 36.68% (319) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_4726 | - | 5e-50 | 33.48% (454) | hypothetical protein Mvan_4726 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1918|M.gilvum_PYR-GCK --------------------MGKGDFGLKASEFTGRSSTRFADSVRRRPG
MSMEG_5455|M.smegmatis_MC2_155 --------------------MGRLLHSLSTAFLVFVAVVVLCVSTS----
Mb1465|M.bovis_AF2122/97 MSFVFAVPEMVAATASDLASLGAALSEATAAAAIPTTQVLAAAADEVSAA
Rv1430|M.tuberculosis_H37Rv MSFVFAVPEMVAATASDLASLGAALSEATAAAAIPTTQVLAAAADEVSAA
MMAR_2235|M.marinum_M MSFVVTAPETVVAAASQLTGIGSAIEAANAAAAALTTRLLPAAADEVSAG
MUL_1034|M.ulcerans_Agy99 MSYVLTAPDLLASAATDVDGIAATLQVANSAAAALTSGLLAAAQDEVSAA
MLBr_01232|M.leprae_Br4923 --------------------MKRLLATTLAALTVGTVSGFGSTVASSEPG
MAV_1760|M.avium_104 --------------------MKQLLAGVTALLSVSTAGYFGIGTAAADGG
TH_3724|M.thermoresistible__bu ------------------------VVAVGALTWGGXGVASPAGQPER---
Mvan_4726|M.vanbaalenii_PYR-1 --------------------MRRRLRSAAWGLLSLVIAVLFAWGSVVT--
MAB_4141|M.abscessus_ATCC_1997 -------------------MAGQYSVPGKRHSLRRYVATITAVAATCT--
Mflv_1918|M.gilvum_PYR-GCK GATYGLYRHDGLGVGTWAWVFARSSRSFPRSRRCWRYPRGVPTPVAVLVA
MSMEG_5455|M.smegmatis_MC2_155 ----------------------------------------MPTAAHLLLN
Mb1465|M.bovis_AF2122/97 IAELFGAHGQEFQALSAQASAFHDRFVRALSAAAGWYVDAEAANAALVD-
Rv1430|M.tuberculosis_H37Rv IAELFGAHGQEFQALSAQASAFHDRFVRALSAAAGWYVDAEAANAALVD-
MMAR_2235|M.marinum_M IAALMSTHAQEYQLLGGQLATYHDQLVQALDRTAGWYADAETGNAALLRN
MUL_1034|M.ulcerans_Agy99 IAKVFSAYGQEYQAAIAQASAFHTEFTRALAAAGAAYAQAEAANASLITA
MLBr_01232|M.leprae_Br4923 E------------------------------------PWLPPSPVPVREN
MAV_1760|M.avium_104 P------------------------------------IGGPPTPGAPGD-
TH_3724|M.thermoresistible__bu -----------------------------------------AAALRLTAT
Mvan_4726|M.vanbaalenii_PYR-1 -----------------------------------------STSA--GAG
MAB_4141|M.abscessus_ATCC_1997 ----------------------------------------VLAPLAMESR
Mflv_1918|M.gilvum_PYR-GCK -------------------------------------------NTTALVM
MSMEG_5455|M.smegmatis_MC2_155 -------------------------------------------HPHALVI
Mb1465|M.bovis_AF2122/97 -----------------------TAATGAS--------ELGSGGRTALIL
Rv1430|M.tuberculosis_H37Rv -----------------------TAATGAS--------ELGSGGRTALIL
MMAR_2235|M.marinum_M VQQELLTGLTAPGRAWS---GAGAASAGASGVDALMSSALLSGGRSVLVV
MUL_1034|M.ulcerans_Agy99 GVSDALTAITTPIQSLLGPAAIGTGGAGSAGALTAVSSTLMADPVVALIM
MLBr_01232|M.leprae_Br4923 -----------------------------------------SPAKIVYAL
MAV_1760|M.avium_104 --------------------------------------------QTAYAL
TH_3724|M.thermoresistible__bu --------------------------------------------ADAIIM
Mvan_4726|M.vanbaalenii_PYR-1 ---------------------------------------------TALVM
MAB_4141|M.abscessus_ATCC_1997 --------------------------------------------TIASTL
. :
Mflv_1918|M.gilvum_PYR-GCK GGTFHPLTGPRDSPEFVTAYLDNAVDNQISAAYGYAVTNAVAV-YTPEEF
MSMEG_5455|M.smegmatis_MC2_155 GGTGTPVP----PPEYVNGQTDNYIGAEFPGEYRYAVH-------TPQNF
Mb1465|M.bovis_AF2122/97 GSTGTPRP----PFDYMQQVYDRYIAPHYLGYAFSGLY-------TPAQF
Rv1430|M.tuberculosis_H37Rv GSTGTPRP----PFDYMQQVYDRYIAPHYLGYAFSGLY-------TPAQF
MMAR_2235|M.marinum_M GSTGTPRP----SYRFMREVYDLFVAPHYFGDSLFGVQ-------TPAQF
MUL_1034|M.ulcerans_Agy99 GGTSVPLP----GPGYVSDINNNYIQPLFSGAIPQALF-------TPEQF
MLBr_01232|M.leprae_Br4923 GGARPPTFD---WDYYTIRAGDEFFPDVNRKLIDYPARAPFR--YVPTFL
MAV_1760|M.avium_104 GGAHVLGIP---YDQYIRMEGADWFPGQQRQIVRYPAGQVQG--HVLERL
TH_3724|M.thermoresistible__bu PGTKIGYIP---SQDEFTAYATAVIGATAGAPGAVDYLG------VPGEF
Mvan_4726|M.vanbaalenii_PYR-1 GGNGHPLSVPQDTPDYINKYVTAADDAFIAPSGLCGPQCSLVATYTPAQI
MAB_4141|M.abscessus_ATCC_1997 ASYVIGIGG---NNDGASANIPRKLGGAYSVDYHPVSY--------PGAI
. :
Mflv_1918|M.gilvum_PYR-GCK FPLG------------G-LTFDDSVAEGLANLGRCLRAEPGCVFNADPAV
MSMEG_5455|M.smegmatis_MC2_155 WPVY------------GSMSFDESTVAGLAALQAEMAKEG----------
Mb1465|M.bovis_AF2122/97 QPWT----------GIPSLTYDQSVAEGAGYLHTAIMQQVAA--------
Rv1430|M.tuberculosis_H37Rv QPWT----------GIPSLTYDQSVAEGAGYLHTAIMQQVAA--------
MMAR_2235|M.marinum_M QPFT----------GIPNLTFDESAATGASYLHAAITQQLAD--------
MUL_1034|M.ulcerans_Agy99 WPVTP---------GLGNLTFNQSVAQGVTLLNDAINTQLAL--------
MLBr_01232|M.leprae_Br4923 VPGP-----------RDEVTIGEAIAVATKNLNQAIHRGTEP--------
MAV_1760|M.avium_104 FPGIGKLDESFPGLGMDGPSVGESVAEGIDNLDAAIRTTGRP--------
TH_3724|M.thermoresistible__bu WPATG----------LDSLTFDASVAXGQAMLTPMVDGAIES--------
Mvan_4726|M.vanbaalenii_PYR-1 RFVNG----------IFDMTYDESVAVGQANLNDCIQGSDCTATLAPYSE
MAB_4141|M.abscessus_ATCC_1997 WPVSG----------LTAPTFKTSVAQGRTNLNDEIVTAGNQ--------
: : . . * :
Mflv_1918|M.gilvum_PYR-GCK AARVGTVAPRHDDTFVVFGYSQSAAVASLLK---RQLIDAPGPEPAATTF
MSMEG_5455|M.smegmatis_MC2_155 ---------HFGSPLVILGYSSSTRILTADK---NRRIAD-GDYAVDINY
Mb1465|M.bovis_AF2122/97 -----------GNDVVVLGFSQGASVATLEMRHLASLPAGVAPSPDQLSF
Rv1430|M.tuberculosis_H37Rv -----------GNDVVVLGFSQGASVATLEMRHLASLPAGVAPSPDQLSF
MMAR_2235|M.marinum_M -----------GNRVVVAGFSQGASVATLEMRHLQSLPIDSRPSPEDLSF
MUL_1034|M.ulcerans_Agy99 -----------GNKVVAFGYSQSATIVNNEILALMAMGTG-APDPGDLSF
MLBr_01232|M.leprae_Br4923 --------------AAVVGLSQGSLALDTEQE--QLATDPTAPPPDQLTF
MAV_1760|M.avium_104 --------------GTAIGLSEGAFVVDGEQA--RLANDPTAPPPNTLNF
TH_3724|M.thermoresistible__bu -----------DTPIVVFGHSQSAVIATKEKQRLLAEYPDPDTAP-DVTF
Mvan_4726|M.vanbaalenii_PYR-1 TG----PHTVADSTYVIYAYSQSATVAANQK-----LQLIAHPVASTVSF
MAB_4141|M.abscessus_ATCC_1997 -------------PITIVGYSLGAVVVSKSHS---DLLQRYPGGNPNIQF
. . * .: :
Mflv_1918|M.gilvum_PYR-GCK MLAANPMRPNGGVLGRFPALTIPILGITFHGATPTAGVDG-AYRTVDVVR
MSMEG_5455|M.smegmatis_MC2_155 VLVSDVAKGNGGVMARFPGWHIPILGVTFDGATRTDSDGY-AFDTKSISF
Mb1465|M.bovis_AF2122/97 VLLGNPNNPNGGILARFPGLYLQSLGLTFNGATPDT-----DYATTIYTT
Rv1430|M.tuberculosis_H37Rv VLLGNPNNPNGGILARFPGLYLQSLGLTFNGATPDT-----DYATTIYTT
MMAR_2235|M.marinum_M VLLGNPNNPNGGILARFPGLYIQSVGLTFNGATPVT-----EYPTTVYTT
MUL_1034|M.ulcerans_Agy99 IMVGAPNNPDGGLLARFPGFYIPFLDVSFNGATPAAN----PYPTSIFTA
MLBr_01232|M.leprae_Br4923 NTFGDPSGYHGFGKSVLASIFRPGDYIPLIDYTMPQRMDS-QYDSNRVVA
MAV_1760|M.avium_104 ATFGDPIGRHAFGQSFLTAMFGVGSVVPALDYTMPPPYES-QYDTNRFVA
TH_3724|M.thermoresistible__bu VMVANPNRPNGGLLARFPGLYIPILGVTFNGATPAPADG--PFDSYDVAR
Mvan_4726|M.vanbaalenii_PYR-1 LLVANPNRPDGGILERFVGAYIPLLGITFNGSTPTFSPQPRPLTTVDVAR
MAB_4141|M.abscessus_ATCC_1997 VLMGSANTPNGGIFARFPWLKIPLADIESNGAWEPD-----QFKTKVINT
. .. : : . :
Mflv_1918|M.gilvum_PYR-GCK QYDGLGGDFPVRPLNLLATVNALLGYGIMHG-ETVDVPFAQ-ARFQ----
MSMEG_5455|M.smegmatis_MC2_155 VHDGWS-DFPVYPLNVLALANAVAGIAVLHP-TYPELDRPD-LVPV----
Mb1465|M.bovis_AF2122/97 QYDGFA-DFPKYPLNILADVNALLGIYYSHS-LYYGLTPEQ-VASGIVLP
Rv1430|M.tuberculosis_H37Rv QYDGFA-DFPKYPLNILADVNALLGIYYSHS-LYYGLTPEQ-VASGIVLP
MMAR_2235|M.marinum_M QYDGFA-DFPQYPLNVVADVNALLGISYSHS-LYYGLTPDQ-VAAGVVLP
MUL_1034|M.ulcerans_Agy99 QYDGIA-HAPQYRLNILSDINAIMGYFYVHG-NYPDLMSGQ-AIQ---LP
MLBr_01232|M.leprae_Br4923 AYDGLS-EFPDRADNLLAQLNCFAGGAISHT-PSGFFNPED-VPPQNIRT
MAV_1760|M.avium_104 AYDSIA-DFPDRPDNMFALANTLMGLATGHT-AVAFTNPSM-VPPQNIRT
TH_3724|M.thermoresistible__bu EFDGWA-DFPRYPLNLVATANAILGIYYLHG-GYYELLTENPDILDDPER
Mvan_4726|M.vanbaalenii_PYR-1 QYDGWA-DFPTNPLNLLADLNAIMGTILLHP-NYSDAGTPQ---------
MAB_4141|M.abscessus_ATCC_1997 EYDTYG-DFPAY-FNPLALANSIAAIQYAHPDAYYDRIDPAALDDPDNPN
.* . . * * .: * . . *
Mflv_1918|M.gilvum_PYR-GCK ---GREGDTDYYLIGTDLLPLLQPLLLF----VPRPILSALDAPLRVLVE
MSMEG_5455|M.smegmatis_MC2_155 ---GSTGDTEYFVIGTDIMPLLMPLETIG---VPRPILLAVDEPLRVLVE
Mb1465|M.bovis_AF2122/97 VSSPDT-NTTYILLPNEDLPLLQPLRGI----VPEPLLDLIEPDLRAIIE
Rv1430|M.tuberculosis_H37Rv VSSPDT-NTTYILLPNEDLPLLQPLRGI----VPEPLLDLIEPDLRAIIE
MMAR_2235|M.marinum_M VSSPDV-NTTYILIPNEHLPLLQPLRGI----VPDSVLDGIEPGLRDVVE
MUL_1034|M.ulcerans_Agy99 TSPGYTGNTDYYMYLTQDLPLVQPIRDIPY--AGPPLADLIQPQLRVLVD
MLBr_01232|M.leprae_Br4923 TVNSRGAKTTTYLIPVNHLPLTLPLRYLG---WSDALVDQIDAVLQPKID
MAV_1760|M.avium_104 TINSRGAKDTTIMIPEKHLPLVMPLKYIG---IDENTLNKLDAILTPRVN
TH_3724|M.thermoresistible__bu TIVQQYGDTTYYLIRTEQLPLLRPLRDLG---VPEEFVDALEPYVRRIVD
Mvan_4726|M.vanbaalenii_PYR-1 -LQGQYQDSTYYLIPAPITPVLVPLTWVPI--VGKPLAIALDPAVRVLVE
MAB_4141|M.abscessus_ATCC_1997 VVKTVQGNTTYYLVRAEHLPLLQPLRDLTNPIGASFVLDAIEPTLRVFID
. : *: *: . :: : ::
Mflv_1918|M.gilvum_PYR-GCK DAYDRDAG----PGDPTTARWWPVKDFAGTAAKLIASVPVAVDNLTEGFG
MSMEG_5455|M.smegmatis_MC2_155 AGYRRDIA----PGAPTPARLIPIVNPITLTRNFIAAIPVGVDDAMEELG
Mb1465|M.bovis_AF2122/97 LGYDRTG----YADVPTPAALFPVHIDP----------------------
Rv1430|M.tuberculosis_H37Rv LGYDRTG----YADVPTPAALFPVHIDP----------------------
MMAR_2235|M.marinum_M LGYDRTG----YADVPTPASLFPANVNPNVVAGAFVEGAVRGIDNGLAGM
MUL_1034|M.ulcerans_Agy99 LGYSDYGPGLSYADVPTPAGLL----------------------------
MLBr_01232|M.leprae_Br4923 AAYAYNDN------------------------------------------
MAV_1760|M.avium_104 AGYSRNDD------------------------------------------
TH_3724|M.thermoresistible__bu LGYDRNTP----YGEPAPVRVLPP--------------------------
Mvan_4726|M.vanbaalenii_PYR-1 MGYDRTVN----PGQPTPARYLYVPNLIKAALNFAMAIPTGWDDAISYLT
MAB_4141|M.abscessus_ATCC_1997 MAYDRDTG----PGTTTQFSFFTPSKNIVDAFNKLPTAIAEGAHNVENGL
.*
Mflv_1918|M.gilvum_PYR-GCK ------------------------------LGRVLGTPVPGVFGVGG---
MSMEG_5455|M.smegmatis_MC2_155 ------------------------------HGRPLGTQPSGVFGVGGEDT
Mb1465|M.bovis_AF2122/97 ----------------------------------IAVPPQIGAAIGGP--
Rv1430|M.tuberculosis_H37Rv ----------------------------------IAVPPQIGAAIGGP--
MMAR_2235|M.marinum_M GLPPLPDLPAAPLLPEIWSNAPPIPGWPASVPSAIAVPPQLGGAIAGP--
MUL_1034|M.ulcerans_Agy99 -------------------------------------------SVPNP--
MLBr_01232|M.leprae_Br4923 -------------------------------------------PLNKP--
MAV_1760|M.avium_104 -------------------------------------------PATAP--
TH_3724|M.thermoresistible__bu -----------------------------------------LTPAPGP--
Mvan_4726|M.vanbaalenii_PYR-1 GDP--------------------------DCRPFHTTVPASPFGVGGPPV
MAB_4141|M.abscessus_ATCC_1997 AG--------------------------ATPKQSASPEKPASPPVPQPGP
Mflv_1918|M.gilvum_PYR-GCK ---------------PDLPDVDEGGAVTSDIDEDAVAQRDSASSTERSAP
MSMEG_5455|M.smegmatis_MC2_155 EL-KGLPAGVISLAKPTLPVSSHTTVVEKTERKDLAKPAAEPEPVVEDEP
Mb1465|M.bovis_AF2122/97 --------------LTALDGLLDTVINDQLNPVVTSGIYQAGAELSVAAA
Rv1430|M.tuberculosis_H37Rv --------------LTALDGLLDTVINDQLNPVVTSGIYQAGAELSVAAA
MMAR_2235|M.marinum_M --------------LDHLYRTLDSVINGQINPAITSGIYQYGADLSAEAA
MUL_1034|M.ulcerans_Agy99 --------------FAVSYYLLKGSLQAP---------YGAAVEIGVEAG
MLBr_01232|M.leprae_Br4923 ---------------------------------------ISVDPVNGMDP
MAV_1760|M.avium_104 ---------------------------------------VQVDPVHGFDP
TH_3724|M.thermoresistible__bu ---------------ATQHNAGQGITVASATSTPDKRTPVVEAPVEEPPV
Mvan_4726|M.vanbaalenii_PYR-1 YTGAIDPYGEPTPYLAPPVETHGEAAPGSGSPAAHPAGTEPPETVTFSPT
MAB_4141|M.abscessus_ATCC_1997 TNPGSATTQIPAPEAPTPSVVSLSTAEPPAPPASAKAADPTAISVSTAGA
Mflv_1918|M.gilvum_PYR-GCK AEESRSAVGGADSDGRDDVVDPEPAAPEAETSEAETVT-----------E
MSMEG_5455|M.smegmatis_MC2_155 AVEDETPVADTKKASPKPLRPKVRGPISFDAPKLPTIR-----------K
Mb1465|M.bovis_AF2122/97 GYGAPAGVTNAIFIGQQVLPILVEGPGALVTADTHYLV-----------D
Rv1430|M.tuberculosis_H37Rv GYGAPAGVTNAIFIGQQVLPILVEGPGALVTADTHYLV-----------D
MMAR_2235|M.marinum_M RHGASSELLNAIYVGRQVLPILIEGPGVILTADTYYSI-----------N
MUL_1034|M.ulcerans_Agy99 ------------LLGPESFPDTYPWVPSLNPGLNFYLG-----------Q
MLBr_01232|M.leprae_Br4923 ----IAGIDAELR---DSILNVFAQLRSILPPPPG---------------
MAV_1760|M.avium_104 AEVTAPANQATFGGGADPLSQIMAGAMSVLSHGAGEAD-----------H
TH_3724|M.thermoresistible__bu QTGRSTLKREKPVSARHLVRNSLRAVPGLRRGEPAATP-----------T
Mvan_4726|M.vanbaalenii_PYR-1 TESTPSTLLPETPAESEDMPPDFVENDTPDSDEVSPTE-----------D
MAB_4141|M.abscessus_ATCC_1997 STARDQDFQPDTKPDPKSTPPPTKDSVGEADKSKNTLKPTLRLPKLPVAQ
.
Mflv_1918|M.gilvum_PYR-GCK TEADD---------ADDADDGADADDEDIDADGADADGEDTAGNTAEAA-
MSMEG_5455|M.smegmatis_MC2_155 ATGDRPLKRLLSALTPKRPKPASSHDAGPAAGNKDTDNADKPAARADDAA
Mb1465|M.bovis_AF2122/97 AIQDLAAGDLSGFNQNLQLIPATNIALLVFAAGIPAVAAVAILTGQDFPV
Rv1430|M.tuberculosis_H37Rv AIQDLAAGDLSGFNQNLQLIPATNIALLVFAAGIPAVAAVAILTGQDFPV
MMAR_2235|M.marinum_M AIKDLAAGNLSGFNQNLQLIPATNAMLLTFGATIPIAAGVSAYIGRDFP-
MUL_1034|M.ulcerans_Agy99 PSVTLLSLLSGGLGDIFHLIPPP-----VFP-------------------
MLBr_01232|M.leprae_Br4923 --------------------------------------------------
MAV_1760|M.avium_104 --------------------------------------------------
TH_3724|M.thermoresistible__bu PDVTPDVTPDAPAGQPEPAEPNESAAPPAAAEADDASE------------
Mvan_4726|M.vanbaalenii_PYR-1 DALKDTETINESQDGPTESASGVSGEDAADADSRSADADSLSADAGDSAP
MAB_4141|M.abscessus_ATCC_1997 PGTAPKSPKFPSLKNHLKSVPGLSEKKNPAADASSKHSQPANAPAHTSDK
Mflv_1918|M.gilvum_PYR-GCK -------------
MSMEG_5455|M.smegmatis_MC2_155 -------------
Mb1465|M.bovis_AF2122/97 -------------
Rv1430|M.tuberculosis_H37Rv -------------
MMAR_2235|M.marinum_M -------------
MUL_1034|M.ulcerans_Agy99 -------------
MLBr_01232|M.leprae_Br4923 -------------
MAV_1760|M.avium_104 -------------
TH_3724|M.thermoresistible__bu -------------
Mvan_4726|M.vanbaalenii_PYR-1 ADAAAADTAA---
MAB_4141|M.abscessus_ATCC_1997 TSDHASETGRGAA