For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTNRRSGMLEDSTAAGLPRRGRHRRGRPRRLQPYAWLGAGAVGFGLGAAALTGAGSAHADESAADPSSSS ASSVSSSEDANESRAVSSGADPDDATEDRDPPESEAPESQADTDDSATAEAAVPEETATETDIVDGGGRR AHPGSDAESRAAAVEDLQDDDAATVDLPTDVGGSAAANTEPTAVLSWQSSPGWLTGRVTGRIRAADPDGD RLTYAGTATTGTVAVTSWGSFTYTPSAAARHAAAATDVTPVRATDTFDITVSDGWGGIVAVPVTVRIRPA NSAPAWLRSTVAAPDPATGQVTGRVTATDRDGDVFTYTAAAPSEGAVTVHADGSFTYHPSDAARRRAAST WYTDTDSFRVLLDDGHGATRAITVRVRIAPHNSAPVSGTPTYGPPDPSTGAIGGSVTATDPDGDRITYRL SAPPHRGALVVTGDGRFTYTPTPVARHAAATGRVDSTTDAATVEAGDSLGALTSIPLTFTILPANSVPTS LRATVGQPDSTTGVVTGAVTADDADGDPLTYSGSTVTVKGAVSVAAAGTFVYTPTANARQNAQAPDATAA DRADSFVVTVDDGHGGMATLPVTVAIGSVPVPDPPDPPPPPGALPAFPGAEGFGSLATGGRGGSVVYVTN TNAAGPGSLQWAIDQPGAKYILFKVSGVIDTQIHLTNGDVTIAGQTSPGGITIRGLVTDESPYQDQAVRA PADFAENWILQHIRIRPGLNGPSDDGLRIRYTRNAVLDHVSIGNATDEAVEISYSNNVTIQNSIIAETLG GHSFYGGVLMNYSNPAHGFGLDNIALHHNVINRIEGRLPEGSRESLAAAYSTMNLELSNNLYWDPRFFIA LGPNTNIVTDSSGNPYPIYWNLNAVNNYFRTGPQFPYGMFDDQILRVVGNTLYVSGNRMSSYPSRSDYEL FYCCNDFASVSNPDDSSHRAQKLSARHPFPAITYTPTEMLRAVLRDRAGAWPRDPMDIRLLESVAGDTIS PADPATNPAGDALLPPYTGAAPAAPPDTDGDGMPDAWEVGKGLNPLSANHNATTLSLLGYTDLEVYLHEL SASLVDPARALG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5913 | - | - | 100% (1063) | putative outer membrane adhesin like proteiin |
| M. vanbaalenii PYR-1 | Mvan_1720 | - | e-133 | 48.09% (549) | YVTN beta-propeller repeat-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3594 | - | 2e-81 | 43.50% (423) | YVTN beta-propeller repeat-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2913 | - | 1e-82 | 38.72% (532) | YVTN beta-propeller repeat-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1847 | - | 5e-08 | 22.76% (369) | PPE family protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4365 | - | 4e-08 | 27.60% (279) | hypothetical protein MSMEG_4365 |
| M. thermoresistible (build 8) | TH_3272 | - | 2e-05 | 30.86% (175) | PUTATIVE putative hypothetical protein MSMEG_1629 |
| M. ulcerans Agy99 | MUL_2096 | - | 7e-08 | 23.04% (369) | PPE family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1847|M.marinum_M --------------------------------------------------
MUL_2096|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5913|M.vanbaalenii_PYR-1 ---MVTNRRSGMLEDSTAAGLPRRGRHRRGRPRRLQPYAWLGAGAVGFGL
Mflv_2913|M.gilvum_PYR-GCK MRHSACIGRIGALAFALGVGIGLGATPAVALADETASSSASSEGGPSKPQ
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------MGRIGALAVALGI
MMAR_1847|M.marinum_M --------------------------------------------------
MUL_2096|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5913|M.vanbaalenii_PYR-1 GAAALTGAGSAHADESAADPSSSSASSVSSSEDANESRAVSSGADPDDAT
Mflv_2913|M.gilvum_PYR-GCK RPASESSG--AESDSSDTDTGASHDTNVDTDADAEDRAADADADADVTEV
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 GAALTTGTGVAWADDSGASGGSTSSSSSASDSSSSSAGGSSG--------
MMAR_1847|M.marinum_M --------------------------------------------------
MUL_2096|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5913|M.vanbaalenii_PYR-1 EDRDPPESEAPESQADTDDSATAEAAVPEETATETDIVDGGGRRAHPGSD
Mflv_2913|M.gilvum_PYR-GCK DPEDSTRATPISVQDEATEVDVAEEPEPADSAPALGVPTEAPSPAPEPTN
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1847|M.marinum_M -------------------------------------------MDYAALP
MUL_2096|M.ulcerans_Agy99 -------------------------------------------MDYAALP
Mvan_5913|M.vanbaalenii_PYR-1 AESRA-----AAVEDLQDDDAATVDLPTDVGGSAAANTEPTAVLSWQSSP
Mflv_2913|M.gilvum_PYR-GCK PQAEATVDIPAPPSEEQTPAPMPAPTAVTLSSILSSLLTPTDTPNTPAES
TH_3272|M.thermoresistible__bu ------------------------------------------VVSARRIG
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------SASGGADAAKPR
.
MMAR_1847|M.marinum_M -------------PEINSARMYSGPGSTSMQTAATAWDALATELYSAASC
MUL_2096|M.ulcerans_Agy99 -------------PEINSARMYAGPGSTSMQTAATAWDALATELYSAASC
Mvan_5913|M.vanbaalenii_PYR-1 GWLTGRVTGRIRAADPDGDRLTYAGTATTGTVAVTSWGSFTYTPSAAARH
Mflv_2913|M.gilvum_PYR-GCK PLWLVAAAALRRQIDPATTYQATANSTSLTAEQADAIRRLGEILLDGPPT
TH_3272|M.thermoresistible__bu --------------HLGGWAVAWVGALSLGLGLGAPGVAHADTGPDSRAT
MSMEG_4365|M.smegmatis_MC2_155 --------------KPGVTKPRIQPTGKIAESLKKTAKAVEGAVADAHKR
. . . .
MMAR_1847|M.marinum_M YSSITAG-------------LAGKWQGPAATAMAQAAAPY---AAWLSTT
MUL_2096|M.ulcerans_Agy99 YSSITAG-------------LAGKWQGPAATAMAQAAAPY---AAWLSTT
Mvan_5913|M.vanbaalenii_PYR-1 AAAATDVTPVRATD-TFDITVSDGWGGIVAVPVTVRIRPANSAPAWLRST
Mflv_2913|M.gilvum_PYR-GCK AMVATDTRAYLAHAGSKSITVIDTLKGAVLQTISLRYTPTNLAVTPSGNR
TH_3272|M.thermoresistible__bu EADSEAR------------AVDDGRSARGEVGTASVRRPQVTVGARVGGR
MSMEG_4365|M.smegmatis_MC2_155 AQQSAAQ-------------QAEKRAERRAKLRAQIRPGKDTDKQAPEKQ
:
MMAR_1847|M.marinum_M AAQAELASAQARAAVSAHAG---AFAATVPPPVIAANR------------
MUL_2096|M.ulcerans_Agy99 AAQAELASAQARAAVSAHAG---AFAATVPPPVIAANR------------
Mvan_5913|M.vanbaalenii_PYR-1 VAAPDPATGQVTGRVTATDRDGDVFTYTAAAPSEGAVT------------
Mflv_2913|M.gilvum_PYR-GCK LYISNGIAGTVSVLNTATESVIKTIRVGRTPTALAVNANGSRVYVVNSDD
TH_3272|M.thermoresistible__bu VDTVADSLADPLRKSLDRAR---ASTAPRLSPAAKPGA------------
MSMEG_4365|M.smegmatis_MC2_155 AGNEAKNAAQPATKTQRQLPAAPAVKVPDVITSVRARS------------
. . .
MMAR_1847|M.marinum_M ------AHLAALIATNLLGQNSPAIATTEANYEQMWAQDAAAMYGYAGAC
MUL_2096|M.ulcerans_Agy99 ------AHLAALIATNLLGQNSPAIATTEANYEQMWAQDAAAMYGYAGAC
Mvan_5913|M.vanbaalenii_PYR-1 ------VHADGSFTYHPSDAARRRAASTWYTDTDSFRVLLDDGHGATRAI
Mflv_2913|M.gilvum_PYR-GCK GTVSKISMLTNTVVGKVYGVAEGVSEITISPDGSTIYTLSSTTGQVSRFS
TH_3272|M.thermoresistible__bu ------AEFEAEQVDRLQKMLRPRKTAAVRSDEVTEPDRAAATTDLPPAP
MSMEG_4365|M.smegmatis_MC2_155 ------DEVAREITTGVTGIRTAIENAAPRIALPDLRPTTNLARPVTPVA
. : .
MMAR_1847|M.marinum_M ASATRLTPFTSPPPITDP--------VGLARQGVAATQSTG------ASA
MUL_2096|M.ulcerans_Agy99 ASATRLTPFTSPPPITDP--------VGLARQGVAATQSTG------ASA
Mvan_5913|M.vanbaalenii_PYR-1 TVRVRIAPHNSAPVSGTPTYGPPDPSTGAIGGSVTATDPDGDRITYRLSA
Mflv_2913|M.gilvum_PYR-GCK STALRAQQTVAVTPASQG------ITFSADGSRVFVADIAGSIRVLDAAT
TH_3272|M.thermoresistible__bu APMAIVEPDAVSERSGPD--------WSGPQWSPNPFRPDD-------PA
MSMEG_4365|M.smegmatis_MC2_155 LKAAQPVQVSPPRPTITG-------LVRGLLTAAAGFSPRAATAPVAPAP
..
MMAR_1847|M.marinum_M AAPSLEAVLAASQVITTLPGTLAGLATAPIMTSLNSAFTSLSTSLSKLSS
MUL_2096|M.ulcerans_Agy99 AAPSLEAVLAASQVITTLPGTLAGLVTAPIMTSLNSAFTSLSTSLSKLSS
Mvan_5913|M.vanbaalenii_PYR-1 PPHRGALVVTGDGRFTYTPTPVARHAAATGRVDSTTDAATVEAGDSLGAL
Mflv_2913|M.gilvum_PYR-GCK GQQVDSIAVTAGVPFDIAASPDGTTLYVARSEDGKLSAYDIATKTELTSV
TH_3272|M.thermoresistible__bu PFSMPPLLHDTEKAFVALFPEIFQPFAREGFEAAYRGSQVVPWVNVVVPA
MSMEG_4365|M.smegmatis_MC2_155 SPAAWALLAFARREFERAFTPGAATALAAPAITTSAVTSAAVVNPLPGRL
:
MMAR_1847|M.marinum_M LAVPLNFAMYALNFLDKG---------------------------IGFTK
MUL_2096|M.ulcerans_Agy99 LAVPLNFAMYALNFLDKG---------------------------IGFTK
Mvan_5913|M.vanbaalenii_PYR-1 TSIPLTFTILPANSVPTS---------------------------LRATV
Mflv_2913|M.gilvum_PYR-GCK IANPYEVDGPPLISVSPDGTQLYWAEFGGTRVNVIALVPDNADPVAQAPV
TH_3272|M.thermoresistible__bu TEIVQHLPALLGGDDDAKR-------------------------AMQVVI
MSMEG_4365|M.smegmatis_MC2_155 DSVPVGWVTGVSNPSGNWP--------------------------QTNNT
MMAR_1847|M.marinum_M AATGSLTAAATGAVKAVESGAQSLGSVSLGITGSGAALSAAMG---RGMT
MUL_2096|M.ulcerans_Agy99 AATGSLTAAATGAVKAVESGAQSLGSVSLGITGSGAALSAPMG---RGMT
Mvan_5913|M.vanbaalenii_PYR-1 GQPDSTTGVVTGAVTADDADGDPLTYSGSTVTVKGAVSVAAAG---TFVY
Mflv_2913|M.gilvum_PYR-GCK VNAPNTSGEVTGSVTVTDPEGRPLTYEVITTDKGSVTVTRGADGAFAFTY
TH_3272|M.thermoresistible__bu NELLLTTQPVAVAYYGYDQIADLLNVEYPAQQAKEWFYTTAWD---TLDW
MSMEG_4365|M.smegmatis_MC2_155 AGFDIWGTDLGIMWDGGEWNGQRFVHTAFGDTFSGPNMSGWWRSNVLLIS
: . :
MMAR_1847|M.marinum_M VGALSVPHSWITAPATSAVAAN-----------------LPSSLSSVGTL
MUL_2096|M.ulcerans_Agy99 VGALSVPHSWITAPATSAVAAN-----------------LPSSFSSVGTL
Mvan_5913|M.vanbaalenii_PYR-1 TPTANARQNAQAPDATAADRADSFVVTVDDGHGGMATLPVTVAIGSVPVP
Mflv_2913|M.gilvum_PYR-GCK KATSAARHEAAADDAAPETKQDTFVLTFTDGQRGVVSVPITVTIPPANAA
TH_3272|M.thermoresistible__bu FELLHVRGESGLRDRVS---------------------------------
MSMEG_4365|M.smegmatis_MC2_155 TDNVLSDGLGLVQTGTAYQFIPASGRNLFGLFGGSEVTVIPTAGVQIDGT
..
MMAR_1847|M.marinum_M DS--------------GTAGMPFMPLTGMAG-------RSANGPAASRFE
MUL_2096|M.ulcerans_Agy99 DS--------------GTAGMPFMPLTGMAG-------RSANGPAASRFE
Mvan_5913|M.vanbaalenii_PYR-1 DPPDPPPPPGALPAFPGAEGFGSLATGGRGGSVVYVTNTNAAGPGSLQWA
Mflv_2913|M.gilvum_PYR-GCK PTATVR----SSVSWLSAKVLGTITARDADRDTLTYLASPTAKGGTVTIG
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 QYVN---------------YMSVRSWDTPGRWTTNFSAISVYDPSTDTWV
MMAR_1847|M.marinum_M LRS-------------------------TVVPRSPAAG------------
MUL_2096|M.ulcerans_Agy99 LRS-------------------------TVVPRSPAAG------------
Mvan_5913|M.vanbaalenii_PYR-1 IDQPGAKYILFKVSGVIDTQIHLTNGDVTIAGQTSPGGITIRGLVTDESP
Mflv_2913|M.gilvum_PYR-GCK NDG-----------------------RFTYTPTAAARHAAANANATEADK
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 LAP-----------------------------STIRSAGWFRSSTLYVPG
MMAR_1847|M.marinum_M --------------------------------------------------
MUL_2096|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5913|M.vanbaalenii_PYR-1 YQDQAVRAPADFA-ENWILQHIRIRPGLNGPSDDGLRIRYTRNAVLDHVS
Mflv_2913|M.gilvum_PYR-GCK QDTFDVVINDGHGGLTTLTVTVTVKPGNDAPDARVRTTASWFGPEVYGTV
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 SQNFQQAAYVLQPEDQVGEDGIRYLYAFGTPSGRAGSAYLSRVPEDAVTD
MMAR_1847|M.marinum_M --------------------------------------------------
MUL_2096|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5913|M.vanbaalenii_PYR-1 IGNATDEAVEISYSNNVTIQNSIIAETLGGHSFYGGVLMNYSNPAHGFGL
Mflv_2913|M.gilvum_PYR-GCK VARDQDRDGLTFTASDTAKGGVIVMDSRGRFTYTPAEAARHAAAAAEATA
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 LSKYEYWDGNRWVTGNAAVAAPVIGDSTRSTGLFGFIVDWANDPNVLGGY
MMAR_1847|M.marinum_M --------------------------------------------------
MUL_2096|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5913|M.vanbaalenii_PYR-1 DN--IALHHNVINRIEGRLPEGSRESLAAAYSTMNLELSNNLYWDPRFFI
Mflv_2913|M.gilvum_PYR-GCK ADKQDTFDITVDDGHGGVTTVAVTVRIKPVNAAPRGASAAELFANPNSGL
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 LGGLVGAKTGGNVSELSVQYNEYLGKYVVLYGDGNNNIQMRIADRPEGPW
MMAR_1847|M.marinum_M --------------------------------------------------
MUL_2096|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5913|M.vanbaalenii_PYR-1 ALGPNTNIVTDSSGNPYPIYWNLNAVNNYFRTGPQFPYGMFDDQILRVVG
Mflv_2913|M.gilvum_PYR-GCK TTGKITAVDADGDSLTYRVSPSTGRGIVDVATDGTFTY--------RPTE
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 SDPIELASSADYPGLYAPMIHPWSGTG------------------MLEDD
MMAR_1847|M.marinum_M --------------------------------------------------
MUL_2096|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5913|M.vanbaalenii_PYR-1 NTLYVSGNRMSSYPSRSDYELFYCCNDFASVSNPDDSSHRAQKLSARHPF
Mflv_2913|M.gilvum_PYR-GCK AAREAASRPFAPSWVRTDRFRVTVDDGHGGTTTLTVRVPIAPTGYVNQAP
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 NGDPDVNNLYWNMSLWGDYNVVLMQTDLSGLKTVAV--------------
MMAR_1847|M.marinum_M --------------------------------------------------
MUL_2096|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5913|M.vanbaalenii_PYR-1 PAITYTPTEMLRAVLRDRAGAWPRDPMDIRLLESVAGDTISPADPATNPA
Mflv_2913|M.gilvum_PYR-GCK TDGKYTAGQPNPSSGKVSGTVTAADPERDDIYYLGSGQTAKGGTVVVERD
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1847|M.marinum_M --------------------------------------------------
MUL_2096|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5913|M.vanbaalenii_PYR-1 GDALLPPYTGA-APAAPPDTDGDGMPDAWEVGKGLNPLSANHNATTLSLL
Mflv_2913|M.gilvum_PYR-GCK GRFVYTPTDAARQQAASPDASDEDRQDSFVVTAIDQYAATLAVPVTVSIL
TH_3272|M.thermoresistible__bu --------------------------------------------------
MSMEG_4365|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1847|M.marinum_M ------------------------
MUL_2096|M.ulcerans_Agy99 ------------------------
Mvan_5913|M.vanbaalenii_PYR-1 GYTDLEVYLHELSASLVDPARALG
Mflv_2913|M.gilvum_PYR-GCK PWAASIAGLV--------------
TH_3272|M.thermoresistible__bu ------------------------
MSMEG_4365|M.smegmatis_MC2_155 ------------------------