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MPRPARYTTDVLLDAAAELLAAEGPAAVTMSAVARSTGAPSGSVYHRFPTRAALCGELWVRTEERFQGEL IEALSVDGDAQQRCVSGALRIVQWCRDNPVEAQVMLAGPTELGMGDWPEPVTSRRKRLQRKLRKALSDLS DDTARVNAAIVDVPAAIVRRHLRAGQTIPAVADAIVEECARALIAPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1548 | - | - | 100% (187) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5831 | - | 9e-15 | 28.65% (178) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5303 | - | 2e-11 | 27.08% (192) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4881 | - | 8e-81 | 75.38% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 1e-05 | 26.00% (100) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4625 | - | 2e-25 | 35.75% (193) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4335 | - | 8e-08 | 27.47% (182) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4715 | - | 3e-17 | 33.16% (187) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0859 | - | 2e-19 | 34.09% (176) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2228 | - | 1e-08 | 31.53% (111) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_0145 | - | 1e-07 | 37.50% (72) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1255c|M.tuberculosis_H37Rv -MAGTDWLSARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRA
TH_2228|M.thermoresistible__bu -MTG-NWLADRRTEVAAERILDAAHELFTRHDAATVGMRDIARAAGCSRA
Mvan_1548|M.vanbaalenii_PYR-1 --------MPRPARYTTDVLLDAAAELLAAEGPAAVTMSAVARSTGAPSG
Mflv_4881|M.gilvum_PYR-GCK --------MPRPARYTVDVLLDAAAELLAAEGPAAVTMSAVARSTGAPSG
MAV_4715|M.avium_104 ------------------MILDAARALVLDGGPRTASVAAIATASGAPAG
MSMEG_0859|M.smegmatis_MC2_155 --------MAPPRKHETDAILDAARALVLTEGPRAAGVAAIAKASGAPVG
MAB_4625|M.abscessus_ATCC_1997 --------MGRKPQYSADDILDAALGLVAAGGPSAATATAIGRVLGAPSG
MMAR_4335|M.marinum_M MSTDSHGRRWAKTDATQRRILDAATEVFATRGFNAATMAEVVASSGASIG
MUL_0145|M.ulcerans_Agy99 MSTDSHGRRWAKTDATQRRILDAATEVFATRGFNAATMAEVVASSGASIG
:**** :. . : : *.. .
Rv1255c|M.tuberculosis_H37Rv TLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEPAER---LLVSIT
TH_2228|M.thermoresistible__bu TLYRYFDSREALHTAYVHREARRLYRELGPRLAAIGDPQNR---LIEGIL
Mvan_1548|M.vanbaalenii_PYR-1 SVYHRFPTRAALCGELWVRTEERFQGELIEALSVDGDAQQR---CVSGAL
Mflv_4881|M.gilvum_PYR-GCK SVYHRFPTRAALCGELWVRTEERFQEELLEALSGDGDPQNR---CVAGAL
MAV_4715|M.avium_104 TLYHRFGNRDGILTAAWLRALERFQARALAADG-DTPEDTA---VAMAV-
MSMEG_0859|M.smegmatis_MC2_155 TLYHRFGNRDGILKATWLRGIERFQRRAMAADG-ATPVDVA---VAMAG-
MAB_4625|M.abscessus_ATCC_1997 SIYHRFPSRDELMARLWLRSIARYQDGVLTALA-LPDADDA---LAAAID
MMAR_4335|M.marinum_M SIYHHFGGKTELFLAIFEQMASAVEGKIEEALQQAGDETDRRRIFELGVR
MUL_0145|M.ulcerans_Agy99 SIYHHFGGKTELFLAIFEQMASAVEGKIEEALQQAGDETDRRRIFELGVR
::*: * : : : .
Rv1255c|M.tuberculosis_H37Rv TTLRMVRDNPALAAWFTTTRP-------PIGGEMAGRSEVIAALAAAFLN
TH_2228|M.thermoresistible__bu AALDAVRENPALSSWFAAGHR-------PVGAELADRSEVIHGLVAGFLR
Mvan_1548|M.vanbaalenii_PYR-1 RIVQWCRDNPVEAQVMLAGPTELGMGDWPEP-VTSRRKRLQRKLRKALSD
Mflv_4881|M.gilvum_PYR-GCK RNMQWCRENPVEAHVLLAGPDQLDMGEWPDT-VAGRRKRLQRKLRKVLAE
MAV_4715|M.avium_104 AAVSFARALPDDARLLLTIRPGDLLDGEPDAAFRQTLAAMNAPLTQRLAQ
MSMEG_0859|M.smegmatis_MC2_155 AVLQFARDEPEDARLLLSIRRADLLDGGPDADFDATLADMNAPVFERLHE
MAB_4625|M.abscessus_ATCC_1997 HAFDWTASNHNEALLLLQYEKADLVAHWPDT-LATELKSLNSRVRKTLRE
MMAR_4335|M.marinum_M AYLDGLWEHRRVARLLASGDR-------PTDFGITRRDRMTSAFRSWMAV
MUL_0145|M.ulcerans_Agy99 AYLDGLWEHRRVARLLASGDR-------PTDFGITRRDRMTSAFRSWMAV
. : : * : . :
Rv1255c|M.tuberculosis_H37Rv SLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAEFVVPIVTPA
TH_2228|M.thermoresistible__bu SQGFDDD---GRRARWLVRVIVSLLLFPGRDEAEERALLEDFVVPAVAQA
Mvan_1548|M.vanbaalenii_PYR-1 LSD-DTARVN--------AAIVDVPAAIVRRHLRAGQTIPAVADAIVEEC
Mflv_4881|M.gilvum_PYR-GCK IAG-DHGRIDGRVDGRVAAAVMDVPAAIVRRHLRARQSIPAAADDIVADC
MAV_4715|M.avium_104 LARHLYGNARPRSVDAVARAVADLPYAVVRRHAHDDPMPS-WLETDVAAS
MSMEG_0859|M.smegmatis_MC2_155 LARGIFGRDDDRAMDAVMRAVADLPYATVRRHIDDGKWPV-WLSEDLATS
MAB_4625|M.abscessus_ATCC_1997 YTDRRYGKVTTERIDKVMFALIDMPYAAVRRHLPDKGEPAPWLREFVHTS
MMAR_4335|M.marinum_M LELDSSLHGQFLSRALLAIMEESSLMVAACEEPEQVKPVIDATIEWIGRL
MUL_0145|M.ulcerans_Agy99 LELDSSLHGQFLSRALLR--------------------------SWRSRH
Rv1255c|M.tuberculosis_H37Rv SAAARKAGHPGPE-------------------------------------
TH_2228|M.thermoresistible__bu TE------------------------------------------------
Mvan_1548|M.vanbaalenii_PYR-1 ARALIAPS------------------------------------------
Mflv_4881|M.gilvum_PYR-GCK ARALICPN------------------------------------------
MAV_4715|M.avium_104 ARAVLRS-------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 VRRLLSVDKIVSASREIAAPSDVIFELIADPAQQPRWDGNENLLRMASGG
MAB_4625|M.abscessus_ATCC_1997 AHALLAR-------------------------------------------
MMAR_4335|M.marinum_M TE------------------------------------------------
MUL_0145|M.ulcerans_Agy99 --------------------------------------------------
Rv1255c|M.tuberculosis_H37Rv --------------------------------------------------
TH_2228|M.thermoresistible__bu --------------------------------------------------
Mvan_1548|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4881|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4715|M.avium_104 --------------------------------------FGERP-------
MSMEG_0859|M.smegmatis_MC2_155 RVRGVGEVFTMEIKQGGFRDNHVIEFEEGRRIAWRPAVAGEQPLGHLWRW
MAB_4625|M.abscessus_ATCC_1997 -------------------------------------ACLNEP-------
MMAR_4335|M.marinum_M --------------------------------------------------
MUL_0145|M.ulcerans_Agy99 --------------------------------------------------
Rv1255c|M.tuberculosis_H37Rv --------------------------------------------------
TH_2228|M.thermoresistible__bu --------------------------------------------------
Mvan_1548|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4881|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4715|M.avium_104 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 ELQPAGEGRTLVTHTYDWTQLTDEKRFPKASATTADKLQESVDRLAAIVE
MAB_4625|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4335|M.marinum_M --------------------------------------------------
MUL_0145|M.ulcerans_Agy99 --------------------------------------------------
Rv1255c|M.tuberculosis_H37Rv -
TH_2228|M.thermoresistible__bu -
Mvan_1548|M.vanbaalenii_PYR-1 -
Mflv_4881|M.gilvum_PYR-GCK -
MAV_4715|M.avium_104 -
MSMEG_0859|M.smegmatis_MC2_155 G
MAB_4625|M.abscessus_ATCC_1997 -
MMAR_4335|M.marinum_M -
MUL_0145|M.ulcerans_Agy99 -