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VAPPRKHETDAILDAARALVLTEGPRAAGVAAIAKASGAPVGTLYHRFGNRDGILKATWLRGIERFQRRA MAADGATPVDVAVAMAGAVLQFARDEPEDARLLLSIRRADLLDGGPDADFDATLADMNAPVFERLHELAR GIFGRDDDRAMDAVMRAVADLPYATVRRHIDDGKWPVWLSEDLATSVRRLLSVDKIVSASREIAAPSDVI FELIADPAQQPRWDGNENLLRMASGGRVRGVGEVFTMEIKQGGFRDNHVIEFEEGRRIAWRPAVAGEQPL GHLWRWELQPAGEGRTLVTHTYDWTQLTDEKRFPKASATTADKLQESVDRLAAIVEG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0859 | - | - | 100% (337) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6556 | - | 2e-20 | 35.58% (163) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4744 | - | 4e-11 | 35.20% (125) | hypothetical protein MSMEG_4744 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0091 | - | 2e-08 | 30.83% (120) | hypothetical protein Mb0091 |
| M. gilvum PYR-GCK | Mflv_3232 | - | 2e-24 | 38.16% (152) | hypothetical protein Mflv_3232 |
| M. tuberculosis H37Rv | Rv0088 | - | 3e-08 | 30.83% (120) | hypothetical protein Rv0088 |
| M. leprae Br4923 | MLBr_02497 | - | 6e-10 | 32.28% (127) | hypothetical protein MLBr_02497 |
| M. abscessus ATCC 19977 | MAB_3395 | - | 7e-52 | 56.19% (194) | putative transcriptional regulator, TetR |
| M. marinum M | MMAR_0253 | - | 5e-46 | 58.74% (143) | hypothetical protein MMAR_0253 |
| M. avium 104 | MAV_4715 | - | 2e-61 | 67.22% (180) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4053 | - | 4e-09 | 28.89% (135) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4861 | - | 3e-46 | 58.74% (143) | hypothetical protein MUL_4861 |
| M. vanbaalenii PYR-1 | Mvan_1548 | - | 5e-19 | 34.09% (176) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3395|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4715|M.avium_104 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1548|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0253|M.marinum_M --------------------------------------------------
MUL_4861|M.ulcerans_Agy99 --------------------------------------------------
Mb0091|M.bovis_AF2122/97 MSVYKHAPSRVRLRQTRSTVVKGRSGSLSWRRVRTGDLGLAVWGGREEYR
Rv0088|M.tuberculosis_H37Rv MSVYKHAPSRVRLRQTRSTVVKGRSGSLSWRRVRTGDLGLAVWGGREEYR
Mflv_3232|M.gilvum_PYR-GCK --------------------------------------------------
TH_4053|M.thermoresistible__bu --------------------------------------------------
MLBr_02497|M.leprae_Br4923 --------------------------------------------------
MAB_3395|M.abscessus_ATCC_1997 --------MAPERKHASDAILDAARSLLLDGGPRAATIAAIAGASGAPPG
MAV_4715|M.avium_104 ------------------MILDAARALVLDGGPRTASVAAIATASGAPAG
MSMEG_0859|M.smegmatis_MC2_155 --------MAPPRKHETDAILDAARALVLTEGPRAAGVAAIAKASGAPVG
Mvan_1548|M.vanbaalenii_PYR-1 --------MPRPARYTTDVLLDAAAELLAAEGPAAVTMSAVARSTGAPSG
MMAR_0253|M.marinum_M MVDTDAP------------LPDRSERVVSATREIAAGAAQIFELIADP--
MUL_4861|M.ulcerans_Agy99 MVDTDAP------------LPDRSERVVSATREIAAGAAQIFELIADP--
Mb0091|M.bovis_AF2122/97 AVKPGTPGIQPKGDMMTVTVVDAGPGRVSRSVEVAAPAAELFAIVADP--
Rv0088|M.tuberculosis_H37Rv AVKPGTPGIQPKGDMMTVTVVDAGPGRVSRSVEVAAPAAELFAIVADP--
Mflv_3232|M.gilvum_PYR-GCK ---------------------MSDETKVTVERTITAPVDAIFDVLSNP--
TH_4053|M.thermoresistible__bu -----------------MSDIQTTGTSLAVHTTVNAPARTVFDVLADP--
MLBr_02497|M.leprae_Br4923 --------------------MFASRAALLGRVWLRAGYRFLKTQTALVDQ
: . : .
MAB_3395|M.abscessus_ATCC_1997 TLNHRFGNRAAIMSATWLRAVERFHEHALRALHSAGDPVETA-VALSLSV
MAV_4715|M.avium_104 TLYHRFGNRDGILTAAWLRALERFQARALAADGDT--PEDTA-VAMAVAA
MSMEG_0859|M.smegmatis_MC2_155 TLYHRFGNRDGILKATWLRGIERFQRRAMAADGAT--PVDVA-VAMAGAV
Mvan_1548|M.vanbaalenii_PYR-1 SVYHRFPTRAALCGELWVRTEERFQGELIEALSVDGDAQQRC-VSGALRI
MMAR_0253|M.marinum_M SRQPDWDGNDNLAHCAAGQRVHRVGDVFRMTLTLGSVRENHIVEFTEARL
MUL_4861|M.ulcerans_Agy99 SRQPDWDGNDNLAHCAAGQRVHRVGDVFRMTLTLGSVRENHIVEFTEARL
Mb0091|M.bovis_AF2122/97 RRHRELDGSGTVRGNIKVPAKLVVGSKFSTKMKLFGLPYR-----ITSRV
Rv0088|M.tuberculosis_H37Rv RRHRELDGSGTVRGNIKVPAKLVVGSKFSTKMKLFGLPYR-----ITSRV
Mflv_3232|M.gilvum_PYR-GCK ERHQELDGSGFVRSVDHADRIQKVGEVFTMNMQGD-HMGGEY--KTDNHV
TH_4053|M.thermoresistible__bu TTHARIDGTGWVREPVDGARLTGAGQIFRMGMYHENHPHRHY--EIANRV
MLBr_02497|M.leprae_Br4923 ALSASVRRAGVEAVVAAADAPVVFAEQYPDSSRLLLTVRREE------LL
MAB_3395|M.abscessus_ATCC_1997 PAFARAYPEDARLLLSLRSADILGAEANS----TLDEMNAPLFTAM----
MAV_4715|M.avium_104 VSFARALPDDARLLLTIRPGDLLDGEPDAAFRQTLAAMNAPLTQRL----
MSMEG_0859|M.smegmatis_MC2_155 LQFARDEPEDARLLLSIRRADLLDGGPDADFDATLADMNAPVFERL----
Mvan_1548|M.vanbaalenii_PYR-1 VQWCRDNPVEAQVMLAG-PTELG-----------MGDWPEPVTSRR----
MMAR_0253|M.marinum_M IAWRPSELGKT--PPGHL-------------------WRWELTPIS----
MUL_4861|M.ulcerans_Agy99 IAWRPSELGKT--PPGHL-------------------WRWELTPIS----
Mb0091|M.bovis_AF2122/97 TALKPNELVEWSHPLGHR-------------------WRWEFESLS----
Rv0088|M.tuberculosis_H37Rv TALKPNELVEWSHPLGHR-------------------WRWEFESLS----
Mflv_3232|M.gilvum_PYR-GCK TGYAKDKLLAWQTAPAGTEPPG-------------WEWLWELESQ----G
TH_4053|M.thermoresistible__bu EVFDPPHAIAWQPGAEPRHIPGRGADATGPVEFGGWIWRYDLAPQHAPGA
MLBr_02497|M.leprae_Br4923 KSFLPNEIEIELRELDAL-----------------------LISLL----
.
MAB_3395|M.abscessus_ATCC_1997 --RDLTRAIYQRGDARSRD--RLLRAVVDLPYAAVRRHMP---TLPGWLE
MAV_4715|M.avium_104 --AQLARHLYGNARPRSVD--AVARAVADLPYAVVRRHAHD-DPMPSWLE
MSMEG_0859|M.smegmatis_MC2_155 --HELARGIFGRDDDRAMD--AVMRAVADLPYATVRRHIDD-GKWPVWLS
Mvan_1548|M.vanbaalenii_PYR-1 --KRLQRKLRKALSDLSDDTARVNAAIVDVPAAIVRRHLRAGQTIPAVAD
MMAR_0253|M.marinum_M GTRTLVTHTYDWTELSDPAR------FPRARATTTVQLRASLDRLAGHAE
MUL_4861|M.ulcerans_Agy99 GTRTLVTHTYDWTELSDPAR------FPRARATTTVQLRASLDRLAGHAE
Mb0091|M.bovis_AF2122/97 PTLTRVTETFDYHAAGAIKNGLKFYEMTGFAKSNAAGIEATLAKLSDQYA
Rv0088|M.tuberculosis_H37Rv PTLTRVTETFDYHAAGAIKNGLKFYEMTGFAKSNAAGIEATLAKLSDQYA
Mflv_3232|M.gilvum_PYR-GCK PGETLVRHTYDWSKVTDKKLL----EKVKFPLVSKDQLSDTLARLAAAVS
TH_4053|M.thermoresistible__bu PAGTRVTLTYDWSQVPAADR-----RAMRFPPFPPEHLVNSLRHLKELAE
MLBr_02497|M.leprae_Br4923 --TRLAVVIWDRKDTGAIDT--ITTCLMDLPTAVLLHRDRLGNKTARKHL
MAB_3395|M.abscessus_ATCC_1997 EDLAAAVRALLASR------------------------------------
MAV_4715|M.avium_104 TDVAASARAVLRSFGERP--------------------------------
MSMEG_0859|M.smegmatis_MC2_155 EDLATSVRRLLSVDKIVSASREIAAPSDVIFELIADPAQQPRWDGNENLL
Mvan_1548|M.vanbaalenii_PYR-1 AIVEECARALIAPS------------------------------------
MMAR_0253|M.marinum_M AAAAGD--------------------------------------------
MUL_4861|M.ulcerans_Agy99 AAAAGD--------------------------------------------
Mb0091|M.bovis_AF2122/97 RGRA----------------------------------------------
Rv0088|M.tuberculosis_H37Rv RGRA----------------------------------------------
Mflv_3232|M.gilvum_PYR-GCK S-------------------------------------------------
TH_4053|M.thermoresistible__bu RDVPR---------------------------------------------
MLBr_02497|M.leprae_Br4923 HAAVRAVLEVGPPP------------------------------------
MAB_3395|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4715|M.avium_104 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 RMASGGRVRGVGEVFTMEIKQGGFRDNHVIEFEEGRRIAWRPAVAGEQPL
Mvan_1548|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0253|M.marinum_M --------------------------------------------------
MUL_4861|M.ulcerans_Agy99 --------------------------------------------------
Mb0091|M.bovis_AF2122/97 --------------------------------------------------
Rv0088|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3232|M.gilvum_PYR-GCK --------------------------------------------------
TH_4053|M.thermoresistible__bu --------------------------------------------------
MLBr_02497|M.leprae_Br4923 --------------------------------------------------
MAB_3395|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4715|M.avium_104 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 GHLWRWELQPAGEGRTLVTHTYDWTQLTDEKRFPKASATTADKLQESVDR
Mvan_1548|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0253|M.marinum_M --------------------------------------------------
MUL_4861|M.ulcerans_Agy99 --------------------------------------------------
Mb0091|M.bovis_AF2122/97 --------------------------------------------------
Rv0088|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3232|M.gilvum_PYR-GCK --------------------------------------------------
TH_4053|M.thermoresistible__bu --------------------------------------------------
MLBr_02497|M.leprae_Br4923 --------------------------------------------------
MAB_3395|M.abscessus_ATCC_1997 -------
MAV_4715|M.avium_104 -------
MSMEG_0859|M.smegmatis_MC2_155 LAAIVEG
Mvan_1548|M.vanbaalenii_PYR-1 -------
MMAR_0253|M.marinum_M -------
MUL_4861|M.ulcerans_Agy99 -------
Mb0091|M.bovis_AF2122/97 -------
Rv0088|M.tuberculosis_H37Rv -------
Mflv_3232|M.gilvum_PYR-GCK -------
TH_4053|M.thermoresistible__bu -------
MLBr_02497|M.leprae_Br4923 -------