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ILDAARALVLDGGPRTASVAAIATASGAPAGTLYHRFGNRDGILTAAWLRALERFQARALAADGDTPEDT AVAMAVAAVSFARALPDDARLLLTIRPGDLLDGEPDAAFRQTLAAMNAPLTQRLAQLARHLYGNARPRSV DAVARAVADLPYAVVRRHAHDDPMPSWLETDVAASARAVLRSFGERP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4715 | - | - | 100% (188) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1113 | - | 6e-17 | 30.89% (191) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_3923 | - | 1e-05 | 27.54% (167) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3277c | - | 7e-05 | 24.06% (187) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4881 | - | 6e-20 | 35.98% (189) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3249c | - | 8e-05 | 24.06% (187) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02497 | - | 2e-08 | 32.28% (127) | hypothetical protein MLBr_02497 |
| M. abscessus ATCC 19977 | MAB_3395 | - | 5e-47 | 54.35% (184) | putative transcriptional regulator, TetR |
| M. marinum M | MMAR_3144 | - | 9e-07 | 32.29% (96) | AcrR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0859 | - | 1e-61 | 67.22% (180) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2910 | - | 1e-06 | 29.71% (138) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4487 | - | 5e-06 | 29.41% (136) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5831 | - | 3e-18 | 33.33% (192) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4715|M.avium_104 ----------------------------------MILDAARALVLDGGPR
MSMEG_0859|M.smegmatis_MC2_155 ------------------------MAPPRKHETDAILDAARALVLTEGPR
MAB_3395|M.abscessus_ATCC_1997 ------------------------MAPERKHASDAILDAARSLLLDGGPR
MLBr_02497|M.leprae_Br4923 --------------------------------------------------
Mvan_5831|M.vanbaalenii_PYR-1 ---------MGPAITERALCYRCPVPRPRVIDLDHLMDAVEQLAADAGPR
Mb3277c|M.bovis_AF2122/97 --------MSTPSATVAPVKRIPYAEASRALLRDSVLDAMRDLLLTRDWS
Rv3249c|M.tuberculosis_H37Rv --------MSTPSATVAPVKRIPYAEASRALLRDSVLDAMRDLLLTRDWS
Mflv_4881|M.gilvum_PYR-GCK ------------------------MPRPARYTVDVLLDAAAELLAAEGPA
MUL_4487|M.ulcerans_Agy99 -----------------MGRTDWLAAHRSEVAADRILDAAERLYTEHDPA
TH_2910|M.thermoresistible__bu MAAVDPAEPSARGSDDAVDDDDVDVDPRKLRSRARLLDAATSLLTSGGVE
MMAR_3144|M.marinum_M -------------MSPARVYGGLSATQRDAQRRALLIDAAVALMGKQGAA
MAV_4715|M.avium_104 TASVAAIATASGAPAGTLYHRFGNRDGILTAAWLRALERFQAR-------
MSMEG_0859|M.smegmatis_MC2_155 AAGVAAIAKASGAPVGTLYHRFGNRDGILKATWLRGIERFQRR-------
MAB_3395|M.abscessus_ATCC_1997 AATIAAIAGASGAPPGTLNHRFGNRAAIMSATWLRAVERFHEH-------
MLBr_02497|M.leprae_Br4923 --------------------MFASRAALLGRVWLRAGYRFLKTQTALVDQ
Mvan_5831|M.vanbaalenii_PYR-1 AVTIRALSQRTAISNGAIYHAFGSRGGLLGQVWLRAARRFLSEQRSAVAR
Mb3277c|M.bovis_AF2122/97 AITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDN------V
Rv3249c|M.tuberculosis_H37Rv AITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDN------V
Mflv_4881|M.gilvum_PYR-GCK AVTMSAVARSTGAPSGSVYHRFPTRAALCGELWVRTEERFQEE-------
MUL_4487|M.ulcerans_Agy99 SIGMNEIARAAGCSRATLYRYFESREALRTAYVHRETLRLGRE-------
TH_2910|M.thermoresistible__bu AVTVDAVTRLSKVARTTLYRHFESTTHLLAEAFERLLPQVTSP-------
MMAR_3144|M.marinum_M ACTVTAVCTESGVTSRYFYQQFRDRDALLRAMFTKISTTFQAV------I
* : : .
MAV_4715|M.avium_104 ALAADGDT--PEDTAVAMAVAAVSFARALPDDARLLLTIRPGDLLDG-EP
MSMEG_0859|M.smegmatis_MC2_155 AMAADGAT--PVDVAVAMAGAVLQFARDEPEDARLLLSIRRADLLDG-GP
MAB_3395|M.abscessus_ATCC_1997 ALRALHSAGDPVETAVALSLSVPAFARAYPEDARLLLSLRSADILG----
MLBr_02497|M.leprae_Br4923 ALSASVR-RAGVEAVVAAADAPVVFAEQYPDSSRLLLTVRREELLKS-FL
Mvan_5831|M.vanbaalenii_PYR-1 ALADGVTPETAVEAVVAAAQCPATFLDGHPATAMYLLALPRNELLGARDV
Mb3277c|M.bovis_AF2122/97 HASLDANVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPDLLQL---
Rv3249c|M.tuberculosis_H37Rv HASLDANVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPDLLQL---
Mflv_4881|M.gilvum_PYR-GCK LLEALSGDGDPQNRCVAGALRNMQWCRENPVEAHVLLAG--PDQLDMGEW
MUL_4487|M.ulcerans_Agy99 IMQQIGDIDDPRDQLITSITATLRMVRQRPALAAWFASTRPPIGGEL---
TH_2910|M.thermoresistible__bu -----PATGDLRDQLIELVHRQAALIDEAPLHLTALAWLALGPDPNS-DA
MMAR_3144|M.marinum_M TKAIPDDTVAPQELAYAPIKALVQMIENDPSMARILFVESGAEPLLR-QL
: * :
MAV_4715|M.avium_104 DAAFRQTLAAMNAPLTQRLAQLARHLYGNARPRSVDAVARAVADLPYAVV
MSMEG_0859|M.smegmatis_MC2_155 DADFDATLADMNAPVFERLHELARGIFGRDDDRAMDAVMRAVADLPYATV
MAB_3395|M.abscessus_ATCC_1997 -AEANSTLDEMNAPLFTAMRDLTRAIYQRGDARSRDRLLRAVVDLPYAAV
MLBr_02497|M.leprae_Br4923 PNEIEIELRELDALLISLLTRLAVVIWDRKDTGAIDTITTCLMDLPTAVL
Mvan_5831|M.vanbaalenii_PYR-1 SDELADDLRGLDGELAGLFIELAEHMWRRRDRHAVAAIRACVVDLPTALL
Mb3277c|M.bovis_AF2122/97 ---ITTDSAPIITRASARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYV
Rv3249c|M.tuberculosis_H37Rv ---ITTDSAPIITRASARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYV
Mflv_4881|M.gilvum_PYR-GCK PDTVAGRRKRLQRKLRKVLAEIAG-DHGRIDGRVDGRVAAAVMDVPAAIV
MUL_4487|M.ulcerans_Agy99 ---------AGQSEVIAGLAAAFLQSLGPEAPAAVERRARWTVRVIVSLL
TH_2910|M.thermoresistible__bu RQPLAGLSARVIEQYRQPFDELLAGAAARDELDDFDTTLAIIQLLGPIVF
MMAR_3144|M.marinum_M RSELMSEFAELVLREARLHLDIPSEVIQVADLAATYGVGGLFEILRRWID
:
MAV_4715|M.avium_104 RRHAHDDPMPSWLETDVAASARAVLRS-----------------------
MSMEG_0859|M.smegmatis_MC2_155 RRHIDDGKWPVWLSEDLATSVRRLLSVDKIVSASREIAAPSDVIFELIAD
MAB_3395|M.abscessus_ATCC_1997 RRHMP--TLPGWLEEDLAAAVRALLASR----------------------
MLBr_02497|M.leprae_Br4923 LHRDR--LGNKTARKHLHAAVRAVLEVGPPP-------------------
Mvan_5831|M.vanbaalenii_PYR-1 LRGQH--PPDPAARDRLTAAVRAVLALTPPTSRNTPAH------------
Mb3277c|M.bovis_AF2122/97 SMPPEADHDVAADLARLITPFAERHGVINVP-------------------
Rv3249c|M.tuberculosis_H37Rv SMPPEADHDVAADLARLITPFAERHGVINVP-------------------
Mflv_4881|M.gilvum_PYR-GCK RRHLRARQSIPAAADDIVADCARALICPN---------------------
MUL_4487|M.ulcerans_Agy99 MFPGQDEADERAMLEEFVAPVVTPFPTRR---------------------
TH_2910|M.thermoresistible__bu AKLTGMKTLTPADRVRIVDDFLVAHRPPTPETA-----------------
MMAR_3144|M.marinum_M GQLNLSTEVLIEHCAGFLGSLGLYTLGQKPDPAASHIQVDINSPAGHNR-
.
MAV_4715|M.avium_104 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 PAQQPRWDGNENLLRMASGGRVRGVGEVFTMEIKQGGFRDNHVIEFEEGR
MAB_3395|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02497|M.leprae_Br4923 --------------------------------------------------
Mvan_5831|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3277c|M.bovis_AF2122/97 --------------------------------------------------
Rv3249c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4881|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4487|M.ulcerans_Agy99 --------------------------------------------------
TH_2910|M.thermoresistible__bu --------------------------------------------------
MMAR_3144|M.marinum_M --------------------------------------------------
MAV_4715|M.avium_104 --------FGERP-------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 RIAWRPAVAGEQPLGHLWRWELQPAGEGRTLVTHTYDWTQLTDEKRFPKA
MAB_3395|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02497|M.leprae_Br4923 --------------------------------------------------
Mvan_5831|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3277c|M.bovis_AF2122/97 --------------------------------------------------
Rv3249c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4881|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4487|M.ulcerans_Agy99 --------------------------------------------------
TH_2910|M.thermoresistible__bu --------------------------------------------------
MMAR_3144|M.marinum_M --------------------------------------------------
MAV_4715|M.avium_104 ---------------------
MSMEG_0859|M.smegmatis_MC2_155 SATTADKLQESVDRLAAIVEG
MAB_3395|M.abscessus_ATCC_1997 ---------------------
MLBr_02497|M.leprae_Br4923 ---------------------
Mvan_5831|M.vanbaalenii_PYR-1 ---------------------
Mb3277c|M.bovis_AF2122/97 ---------------------
Rv3249c|M.tuberculosis_H37Rv ---------------------
Mflv_4881|M.gilvum_PYR-GCK ---------------------
MUL_4487|M.ulcerans_Agy99 ---------------------
TH_2910|M.thermoresistible__bu ---------------------
MMAR_3144|M.marinum_M ---------------------