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PDRLASGRHHLSREQVAANQKQRLFKALAAVMAEKGYSDTTVHDLTTAAGVSKATFYQHFTSKQDCFMSA YARMQQFVIDAIQAAPAAGTPMQRFAALLDRYLGFLALDPTTARLFLVEVNAAGPEAMRQRAQLQQEFVS GVAKVFKARSKADRFACQMLVAGISTLVTNALADADGDAVTALKTPILGFTERVMKVPAGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1169 | - | - | 100% (202) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5079 | - | 9e-10 | 27.27% (176) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0313 | - | 2e-09 | 28.78% (139) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3233 | - | 4e-08 | 22.60% (146) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5172 | - | 5e-71 | 65.99% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3208 | - | 4e-08 | 22.60% (146) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 8e-10 | 24.20% (157) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4541 | - | 2e-10 | 25.37% (134) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4832 | - | 5e-09 | 30.00% (110) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0586 | - | 2e-09 | 36.11% (72) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6480 | - | 1e-08 | 28.70% (108) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0083 | - | 9e-10 | 28.49% (186) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4775 | - | 4e-08 | 40.00% (65) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1169|M.vanbaalenii_PYR-1 -------------------MPDRLASGRHHLSREQVAANQKQRLFKALAA
Mflv_5172|M.gilvum_PYR-GCK -------------------MAERLAAGRHRLSRDEVAAHQKQRLFKALAV
MSMEG_6480|M.smegmatis_MC2_155 ---------------------MTTALTGTATAGGSGGDAFRSRLLDGLST
TH_0083|M.thermoresistible__bu ---------------------MTTAVQ-PADVG-AGDDAFRGRLLSGLAA
MUL_4775|M.ulcerans_Agy99 ---------------------MTAAASSPAALD---SDPFRQRLLEGLVA
Mb3233|M.bovis_AF2122/97 MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
Rv3208|M.tuberculosis_H37Rv MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MAV_0586|M.avium_104 --------------------------------MARWEPDARARLVAAALD
MAB_4541|M.abscessus_ATCC_1997 -------------------MTNLIPESETPNKRERAKADRRDQLLRAAAR
MMAR_4832|M.marinum_M ---------------------------------MRKIPAQISERLPAAAE
. .
Mvan_1169|M.vanbaalenii_PYR-1 VMAEKGYSDTTVHDLTTAAGVSKATFYQHFTSKQDCFMSAYARMQQFVID
Mflv_5172|M.gilvum_PYR-GCK VMGTRGYNKTSVDDLIKHAGVSRATFYELFDSKQDCFMAGFAGMQGHVID
MSMEG_6480|M.smegmatis_MC2_155 AIDDKGYRDSTVADIVRHARTSKRTFYDQFASKEACFIELLRANNAALVE
TH_0083|M.thermoresistible__bu SIAERGYRETTVADIVRHARTSKRTFYDQFGSKEECFQELLWANNIDMIG
MUL_4775|M.ulcerans_Agy99 SIGERGYHATTVADIVRHARTSKRTFYDRFESKEQCFLDLLRADNERLAK
Mb3233|M.bovis_AF2122/97 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
Rv3208|M.tuberculosis_H37Rv VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
MAV_0586|M.avium_104 LFNERGYDQTTVAEIAERAGLTKSTFFRHFPDKRDVLAAGQDAIAQLLRE
MAB_4541|M.abscessus_ATCC_1997 LLAMRGYARVRLEDLGSAVGISGPAIYRHFPNKEALLVDLLTDVSRRLLE
MMAR_4832|M.marinum_M LFAERGLNDTKIEDVAATTGIAKATLYYYFAGKEEILAFLLEDVLQHVAD
: :* : :: . : .:: * .* :
Mvan_1169|M.vanbaalenii_PYR-1 AIQAAP-AAGTPMQRFAALLDRYLGFLALDPTTARLFLVEVNAAGPEAMR
Mflv_5172|M.gilvum_PYR-GCK AILAAP-AGATPLERFGVMLDRYLGFMALDPPTARLYLVEVYSAGPDAMH
MSMEG_6480|M.smegmatis_MC2_155 HIRSAVSPEAEWQDQIDQAVGAYVEHIESAPSITLSWIRELPALGPAARP
TH_0083|M.thermoresistible__bu AIRAAVDPEADWSEQIRQAVVAYVDHIESRPAITLAWIRELPAIGASVRP
MUL_4775|M.ulcerans_Agy99 RIRAAVDPEADWQAQIRQAVEAYLSHIESRLAVTLSWIREFPSLGPISYP
Mb3233|M.bovis_AF2122/97 GVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAA
Rv3208|M.tuberculosis_H37Rv GVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAA
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
MAV_0586|M.avium_104 GIAAAP-ADATPLALVCSGLKSAAAAFTPFNKELAPRLRAAIAASAELQE
MAB_4541|M.abscessus_ATCC_1997 GGMTVAAAASSPAEALDGLIDFHLDFALNESDLIRVQDRDLDSLPENARR
MMAR_4832|M.marinum_M EVTAIVEADGTAAQRLHTVINAQLRVMAQRPAVCRALIGELGRAARMP-A
. . :
Mvan_1169|M.vanbaalenii_PYR-1 QRAQLQQEFVSGVAKVFK----ARSKADRFACQMLVAGISTL-VTNALAD
Mflv_5172|M.gilvum_PYR-GCK RRAELQQQFVDGVAKIFK----ARSKADKFACKALVAAISAL-VTTALID
MSMEG_6480|M.smegmatis_MC2_155 LQRDAMGALTDLLIDLSDSPGFRRAGLNGLSRQMAIILLGGLRELTALIV
TH_0083|M.thermoresistible__bu IQRAMMHELTELLIELSRSPGFARAQMPPLTRQLAVFLLGGLRELTALFV
MUL_4775|M.ulcerans_Agy99 VQRHGMNLLTSLLVELSASPGFRRAGLPAVPGALAVILLGGLRELTALTV
Mb3233|M.bovis_AF2122/97 QVRVATESCIDAVFALIS----ADSGLDPHRARMIAVGLVGMSVDCARYW
Rv3208|M.tuberculosis_H37Rv QVRVATESCIDAVFALIS----ADSGLDPHRARMIAVGLVGMSVDCARYW
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALIS----ADSRLDPHRARMVAVGLVGISVDCARYW
MAV_0586|M.avium_104 RNALKQIGLALAVSEALQ------ARGVPEPAAALAAELGALAFKTAYAR
MAB_4541|M.abscessus_ATCC_1997 QVRQYQRRYVEAWVQVLCR---SQQGLDESDARIKAHAAFGLMNSTPYS-
MMAR_4832|M.marinum_M IADMITTAYFEPVETLLRAGAADGSLVALDKPRAAAIALFGAVTISALTY
.
Mvan_1169|M.vanbaalenii_PYR-1 ADGDAVTALKTPILGFTERVMKVPAGG-----
Mflv_5172|M.gilvum_PYR-GCK GDPAAILALKAPVLTFAERALRAGPS------
MSMEG_6480|M.smegmatis_MC2_155 EDGHDIREIYEPAVAASRAILTASSAEHQAR-
TH_0083|M.thermoresistible__bu EDGRDVRGLIAPAVSASKALLSAGASE-----
MUL_4775|M.ulcerans_Agy99 EDGRDIREIVEPAVDASIALVGPRH-------
Mb3233|M.bovis_AF2122/97 LDADKPISKSDAVEGTVQFAWGGLSHVPLTRS
Rv3208|M.tuberculosis_H37Rv LDADKPISKSDAVEGTVQFAWGGLSHVPLTRS
MLBr_00815|M.leprae_Br4923 LDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL
MAV_0586|M.avium_104 WAEPDESGDLGDMACQALRELHAAAADLG---
MAB_4541|M.abscessus_ATCC_1997 AGRSAPSQTRTVLRQMVVAALRS---------
MMAR_4832|M.marinum_M LITDDALNEELIARTIHDVAFIGLRPR-----