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MTTALTGTATAGGSGGDAFRSRLLDGLSTAIDDKGYRDSTVADIVRHARTSKRTFYDQFASKEACFIELL RANNAALVEHIRSAVSPEAEWQDQIDQAVGAYVEHIESAPSITLSWIRELPALGPAARPLQRDAMGALTD LLIDLSDSPGFRRAGLNGLSRQMAIILLGGLRELTALIVEDGHDIREIYEPAVAASRAILTASSAEHQAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6480 | - | - | 100% (210) | putative transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3425 | - | 5e-06 | 26.75% (157) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4847 | - | 1e-05 | 24.29% (140) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0140c | - | 8e-64 | 64.80% (196) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1103 | - | 7e-60 | 62.57% (179) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0135c | - | 8e-64 | 64.80% (196) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00815 | - | 9e-05 | 27.47% (91) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1149 | - | 3e-05 | 22.53% (182) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0345 | - | 2e-64 | 65.76% (184) | transcriptional regulatory protein |
| M. avium 104 | MAV_5161 | - | 4e-60 | 65.22% (184) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0083 | - | 3e-69 | 63.11% (206) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4775 | - | 3e-64 | 65.22% (184) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5713 | - | 8e-63 | 63.54% (181) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1103|M.gilvum_PYR-GCK ---------------------------------------MNDRLLDGLAS
Mvan_5713|M.vanbaalenii_PYR-1 --------------------MRTTPLAAGPHP------SVADRLLDGLAS
Mb0140c|M.bovis_AF2122/97 --------------------MTAVAAGALVVE----TDSFRLRLLDGLVA
Rv0135c|M.tuberculosis_H37Rv --------------------MTAVAAGALVVE----TDSFRLRLLDGLVA
MMAR_0345|M.marinum_M --------------------MTAAASSPAALD----SDPFRQRLLEGLVA
MUL_4775|M.ulcerans_Agy99 --------------------MTAAASSPAALD----SDPFRQRLLEGLVA
MAV_5161|M.avium_104 --------------------MTATDGEPDLGE----IDPFRLRLLDGLAT
MSMEG_6480|M.smegmatis_MC2_155 --------------------MTTALTGTATAGG-SGGDAFRSRLLDGLST
TH_0083|M.thermoresistible__bu --------------------MTTAVQ-PADVG--AGDDAFRGRLLSGLAA
MAB_1149|M.abscessus_ATCC_1997 ----------------MAVPSRPDVPGRTPRVR-MAGSERRRQLIDVARS
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
:*:
Mflv_1103|M.gilvum_PYR-GCK SIVERGYRETTVADIVRHAKTSKRAFYEQFASKEQCLIELLRNNNTDLIA
Mvan_5713|M.vanbaalenii_PYR-1 AITERGYRDSTVADVVRYARTSKRTFYEQFASKEECLIEMLRRNHSDLIA
Mb0140c|M.bovis_AF2122/97 SIGERGYRATTVSDIVRHARTSKRTFYDRFTSKEQCFLELLLADNETLGN
Rv0135c|M.tuberculosis_H37Rv SIGERGYRATTVSDIVRHARTSKRTFYDRFTSKEQCFLELLLADNETLGN
MMAR_0345|M.marinum_M SIGERGYHATTVADIVRHARTSKRTFYDRFESKEQCFLDLLRADNERLAK
MUL_4775|M.ulcerans_Agy99 SIGERGYHATTVADIVRHARTSKRTFYDRFESKEQCFLDLLRADNERLAK
MAV_5161|M.avium_104 SIGERGYRASTVADVVRCARTSKRTFYDHFAGKEECFLELLAVDIEKLGA
MSMEG_6480|M.smegmatis_MC2_155 AIDDKGYRDSTVADIVRHARTSKRTFYDQFASKEACFIELLRANNAALVE
TH_0083|M.thermoresistible__bu SIAERGYRETTVADIVRHARTSKRTFYDQFGSKEECFQELLWANNIDMIG
MAB_1149|M.abscessus_ATCC_1997 LFAERGYEATSIEEIAQRAGVSKPVVYEHFGGKEGLYAVVVDREMSVLLD
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
: ::**. : : ::. * .** ..*::* .* :: . :
Mflv_1103|M.gilvum_PYR-GCK HINAAVDPESDWREQIGQAVDAYIGHISARPAITLCWIREAPALGAVARP
Mvan_5713|M.vanbaalenii_PYR-1 GIGAAVEPEADWRLQIDKAVGAYIDHISARPAITLCWIREAPGLGAAARP
Mb0140c|M.bovis_AF2122/97 SIRAAVDPNADWHDQIRQAVEAYVTHIESRPAVTLSWIREFPSLGAAAYP
Rv0135c|M.tuberculosis_H37Rv SIRAAVDPNADWHDQIRQAVEAYVTHIESRPAVTLSWIREFPSLGAAAYP
MMAR_0345|M.marinum_M RIRAAVDPEADWQAQIRQAVEAYVSHIESRLAVTLSWIREFPSLGPISYP
MUL_4775|M.ulcerans_Agy99 RIRAAVDPEADWQAQIRQAVEAYLSHIESRLAVTLSWIREFPSLGPISYP
MAV_5161|M.avium_104 KIAASVDPEADWHVQIRQAVEAYVGYIEARPAITLSWIRELPSLGAAARP
MSMEG_6480|M.smegmatis_MC2_155 HIRSAVSPEAEWQDQIDQAVGAYVEHIESAPSITLSWIRELPALGPAARP
TH_0083|M.thermoresistible__bu AIRAAVDPEADWSEQIRQAVVAYVDHIESRPAITLAWIRELPAIGASVRP
MAB_1149|M.abscessus_ATCC_1997 GITSSLTS-YRSRVRLEQVALALLSYIEERTDGFRILIRDSP-PGVSSGT
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
: :: . :: .. * . .*. :.: .
Mflv_1103|M.gilvum_PYR-GCK LHRQVMRDLTEMLTALTGSSGFRRAGLQPIEPAIALILLGGLRELTALFV
Mvan_5713|M.vanbaalenii_PYR-1 LHRLVMGDLTDLLVSLTGNPGFRRAGLDPITAPVALILVGGLRELTALFV
Mb0140c|M.bovis_AF2122/97 VQRRGMEQLTSLLIELSASPGFRRANLPPLNVPLAVILLGGLRELTALTV
Rv0135c|M.tuberculosis_H37Rv VQRRGMEQLTSLLIELSASPGFRRANLPPLNVPLAVILLGGLRELTALTV
MMAR_0345|M.marinum_M VQRHGMNLLTSLLVELSASPGFRRAGLPAVPGALAVILLGGLRELTALTV
MUL_4775|M.ulcerans_Agy99 VQRHGMNLLTSLLVELSASPGFRRAGLPAVPGALAVILLGGLRELTALTV
MAV_5161|M.avium_104 VQRRGLQLLTSLLIDLSASPGFRRAQLPPLTAPLAVILLGGLRELTALAV
MSMEG_6480|M.smegmatis_MC2_155 LQRDAMGALTDLLIDLSDSPGFRRAGLNGLSRQMAIILLGGLRELTALIV
TH_0083|M.thermoresistible__bu IQRAMMHELTELLIELSRSPGFARAQMPPLTRQLAVFLLGGLRELTALFV
MAB_1149|M.abscessus_ATCC_1997 YSSLLNDAVSQVSSILAG--DFQRRGLDAEMAPLYAQALVGQVSMTAQWW
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALIS----ADSRLDPHRARMVAVGLVGISVDCARYW
. * : : : * *
Mflv_1103|M.gilvum_PYR-GCK EDG-RDMRGIAGPATAAAVALLGPH-----------
Mvan_5713|M.vanbaalenii_PYR-1 EDE-RDVHGIAAPAVAAATALVSAG-----------
Mb0140c|M.bovis_AF2122/97 EDG-QPIRNIVEPAVDASIALLGPRS----------
Rv0135c|M.tuberculosis_H37Rv EDG-QPIRNIVEPAVDASIALLGPRS----------
MMAR_0345|M.marinum_M EDG-RDIREIVEPAVDASIALVGPRH----------
MUL_4775|M.ulcerans_Agy99 EDG-RDIREIVEPAVDASIALVGPRH----------
MAV_5161|M.avium_104 EDG-KPVRGIVEPAVDASVALLGPRH----------
MSMEG_6480|M.smegmatis_MC2_155 EDG-HDIREIYEPAVAASRAILTASSAEHQAR----
TH_0083|M.thermoresistible__bu EDG-RDVRGLIAPAVSASKALLSAGASE--------
MAB_1149|M.abscessus_ATCC_1997 LDA-REPKKEVVAAHIVNLCWHGLKHLEADPQLHEE
MLBr_00815|M.leprae_Br4923 LDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL----
* : . .